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No. 24; Updated March 2011
Click here to download and print a PDF version of this document.
Parents are usually the first to recognize that their child has a problem with emotions or behavior. Still, the decision to seek professional help can be difficult and painful for a parent. The first step is to gently try to talk to the child. An honest open talk about feelings can often help. Parents may choose to consult with the child's physicians, teachers, members of the clergy, or other adults who know the child well. These steps may resolve the problems for the child and family.
Following are a few signs which may indicate that a child and adolescent psychiatric evaluation will be useful.
- Marked fall in school performance
- Poor grades in school despite trying very hard
- Severe worry or anxiety, as shown by regular refusal to go to school, go to sleep or take part in activities that are normal for the child's age
- Frequent physical complaints
- Hyperactivity; fidgeting; constant movement beyond regular playing with or without difficulty paying attention
- Persistent nightmares
- Persistent disobedience or aggression (longer than 6 months) and provocative opposition to authority figures
- Frequent, unexplainable temper tantrums
- Threatens to harm or kill oneself
- Marked decline in school performance
- Inability to cope with problems and daily activities
- Marked changes in sleeping and/or eating habits
- Extreme difficulties in concentrating that get in the way at school or at home
- Sexual acting out
- Depression shown by sustained, prolonged negative mood and attitude, often accompanied by poor appetite, difficulty sleeping or thoughts of death
- Severe mood swings
- Strong worries or anxieties that get in the way of daily life, such as at school or socializing
- Repeated use of alcohol and/or drugs
- Intense fear of becoming obese with no relationship to actual body weight, excessive dieting, throwing up or using laxatives to loose weight
- Persistent nightmares
- Threats of self-harm or harm to others
- Self-injury or self destructive behavior
- Frequent outbursts of anger, aggression
- Repeated threats to run away
- Aggressive or non-aggressive consistent violation of rights of others; opposition to authority, truancy, thefts, or vandalism
- Strange thoughts, beliefs, feelings, or unusual behaviors
See other Facts for Families:
#25 Where to Seek Help for Your Child
#52 Comprehensive Psychiatric Evaluation
#57 Normal Adolescent Development, Middle School, and Early High School Years
#58 Normal Adolescent Development, Late High School Year and Beyond
#00 Definition of a Child and Adolescent Psychiatrist
The American Academy of Child and Adolescent Psychiatry (AACAP) represents over 8,500 child and adolescent psychiatrists who are physicians with at least five years of additional training beyond medical school in general (adult) and child and adolescent psychiatry.
Facts for Families© information sheets are developed, owned and distributed by AACAP. Hard copies of Facts sheets may be reproduced for personal or educational use without written permission, but cannot be included in material presented for sale or profit. All Facts can be viewed and printed from the AACAP website (www.aacap.org). Facts sheets may not be reproduced, duplicated or posted on any other website without written consent from AACAP. Organizations are permitted to create links to AACAP's website and specific Facts sheets. For all questions please contact the AACAP Communications & Marketing Coordinator, ext. 154.
If you need immediate assistance, please dial 911.
Copyright © 2012 by the American Academy of Child and Adolescent Psychiatry. | 3.364741 |
adopt many methods to determine whether the unborn baby is a boy or a
girl. The Chinese
pregnancy calendar is an often used
method to know about the
gender of the new life in the mothers womb.
is an ancient way for
predicting the gender of
the unborn baby
It is also known as a Chinese
conception chart, or
the Chinese Conception Calendar. It is believed that this ancient
method is highly accurate, although no clinical studies verify these
chart is an
ancient Chinese secret
A Chinese scientist developed this calendar,
700 years ago. According to a legend, the Chinese
is capable of
predicting the baby gender based
on two variables: the baby month of conception and the mothers age.
chart was kept in a royal tomb, near the city of Peking in China in
ancient times. Now this original Chinese chart is on display at the
Beijing Institute of Science. Many people, especially the Chinese,
believe that the original Chinese pregnancy
calendar is almost 100%
According to studies, the
Chinese pregnancy calendar
has been found to be
97% effective in
predicting a baby gender. This accuracy is credited to the use of
Chinese lunar calendar
pregnancy calendar is dependent on the
lunar calendar. It is
based on the month a baby is conceived and not the birth month. The
second factor is the mothers age at the time of conception, adding 9
months to her age to adjust the lunar calendar.
conceived month from January to December is listed on the top row of
the Chinese chart,
and the left column of
age during the conception. You need to follow the steps given below to
get the most accurate result from the Chinese
Pregnancy by the boy approaches more often , than pregnancy an girl. On
statistical given beside young and sound parents more often birth boys,
but beside of parents of more senior age on the contrary.
1. Note down your age
at the time of conception.
2. Add 9 months to the age to
adjust to the lunar calendar.
3. Also note down the month
when the baby was conceived.
4. Now simply search for the
conceived month across the top portion of the chart and the age on the
left side of the chart.
5. Lastly, follow these two
coordinates to the spot where they intersect, and that will show you
either a box containing B
boy, or G
comparison to the Chinese pregnancy calendar,
the ultrasound during
the 7th or 8th month of
is a more reliable method to
know the gender of the
child. In fact an ultrasound is use to monitor the
week by week
development right from
conception till child birth.
it is a
boy or a girl, what does it matter? What matters is that you have fun
guessing the gender of your unborn baby using the Chinese pregnancy
All along use a
journal to record your
development week by week.
More radio frequency to conceive aihe male sex is connected with
that Spermatozoidum, carrying male Y-chromosome, several more
movable, than carrying X-chromosome, and has more chances earlier to
reach ovules. But healled Spermatozoidum with X-chromosome more viable
and can more long to survive in wombs of pipe, and wait a period of
One of the ways of planning of conceiving boy or girl is based on such
abilities an Spermatozoidum.
In the first place it is necessary exactly
to define a date of ovulations. So, if beside you menstruations
regular, the day of ovulations constant and possible produce an
uncomplicated calculation. If you want conceive boy or girl, You must
adjust last sexual contact before a data of ovulations. If You to
planned conceive of boy or girl
Study has shown that method
efficient in 80% events aproximately.
Used and other ways of planning conceive boy or girl, based on
calculations "biological rhythms", astrological forecasts and etc. But
from medical standpoints these methods not motivated.
a sex of aihe during pregnancy.
By means of the ultrasound during of pregnancy possible to
define a sex of future child. This better and easier to realize at late
terms of pregnancy, after 22-26 weeks. Then results will more | 3.133232 |
Average life span in the wild: 12 years
Size: 21 in (50 cm)
Weight: 14.4 oz (408 g)
Did you know? Chameleons don't change colors to match their surroundings. Each species displays distinct color patterns to indicate specific reactions or emotions.
The Meller's chameleon is the largest of the chameleons not native to Madagascar. Their stout bodies can grow to be up to two feet (two-thirds of a meter) long and weigh more than a pound (one-half kilogram).
Meller's distinguish themselves from their universally bizarre-looking cousins with a single small horn protruding from the front of their snouts. This and their size earn them the common name "giant one-horned chameleon."
They are fairly common in the savanna of East Africa, including Malawi, northern Mozambique, and Tanzania. Almost one-half of the world’s chameleons live on the island of Madagascar.
As with all chameleons, Meller's will change colors in response to stress and to communicate with other chameleons. Their normal appearance is deep green with yellow stripes and random black spots. Females are slightly smaller, but are otherwise indistinguishable from males.
They subsist on insects and small birds, using their camouflage and a lightning-fast, catapulting tongue, which can be up to 20 inches (50 centimeters) long, to ambush prey.
Exotic pet enthusiasts often attempt to keep Meller's chameleons as pets. However, they are highly susceptible to even the slightest level of stress and are very difficult to care for in captivity. In the wild, they can live as long as 12 years. | 3.399523 |
Nuclear Energy in France
Nuclear energy is the cornerstone of french energy policy. In the ‘70s France chose to develop nuclear as its base load electricity source as a response to the oil crisis and assure its energy independence.
Nuclear Electricity Production: France currently counts 58 commercial nuclear reactors in operation responsible for producing 80% of French domestic electricity. As a comparison, the 104 US reactors produces 20% of US electricity.Despite scarce natural resources, France has reached an energy independence of 50% thanks to its strategic choice for nuclear energy.
Environment: As well as providing safe and reliable energy, nuclear helps to reduce French greenhouse gas emissions by avoiding the release of 31 billions tones of carbon dioxide (contrary to coal or gas generation) and making France the less carbon emitting country within the OECD. As a leader in nuclear energy, France has developed clean technology for radioactive waste disposal. Reprocessing currently allows France to recover valuable elements from spent fuels and permit a significant reduction of high level waste and lead to safer and optimized containment, for final radioactive waste disposition. French nuclear power plants produces only 10 g/year/inhabitant of highly radioactive waste.
International Cooperation and research: France is one of the forerunner in nuclear research and participates in numerous international cooperation programs alongside the United States such as the development of the next generation of nuclear power plants (Gen IV) and the International Thermonuclear Experimental Reactor (ITER) that will be built in Cadarache, South of France.
The French Atomic Energy Commission (CEA)
The French Atomic Energy Commission is a public body established in October 1945 by General de Gaulle. It constitutes a power of expertise and proposition for the authorities. A leader in research, development and innovation, the CEA is involved in three main fields:
It develops and acquires the technological building blocks necessary to the development of the nuclear reactors of the future (Contribution to Generation IV and GNEP research),
It contributes to reducing greenhouse gas emission with its research on hydrogen, fuel cells, biomass, energy storage…,
It supports the nuclear utilities in France by optimizing the nuclear power plants of the French nuclear fleet and by optimizing the fuel cycle,
It offers safe and economically viable technical solutions for managing nuclear waste,
It conducts fundamental research in climate and environmental sciences, high energy physics, astrophysics, fusion, nanosciences…
Information and Health technologies:
It tackles micro and nano-technologies for telecommunication and nuclear medicine for radiotherapy and medical imaging,
It researches programs on biotechnology, molecular labelling, biomolecular engineering and structural biology,
It shares its knowledge and know-how through education and training through the National Institute for Nuclear Sciences and Technologies (INSTN),
It manages over 300 priority patents and is active in the creation of clusters.
Defense and National Security:
It conceives, builds, maintains then dismantles the nuclear warhead of the French deterrence force,
It helps to fight against nuclear, biological and chemical weapons (NRBC program).
The missions of the CEA are similar to the Department of Energy in the United States. The CEA has a network of counselor or representatives in French Embassies around the world (see joint map).
The French Nuclear Safety Authority (ASN)
Created in 2006, from the former DSIN (Directorate for the Safety of Nuclear Facilities), the French Nuclear Safety Authority is an independent administrative authority which is tasked with regulating nuclear safety and radiation protection in order to protect workers, patients, the public and the environment from the risks involved in nuclear activities. It also contributes to informing the public. Like the Nuclear Regulatory Commission in the United States, it carries out inspections and may pronounce sanctions, up to and including suspension of operation of an installation.
French Institute for Radioprotection and Nuclear Safety (IRSN)
Created in 2001 by merging the Protection and Nuclear Safety Institute (IPSN) and the Ionizing radiations Protection Office (OPRI), the Institute for Radioprotection and Nuclear Safety is a public establishment of an industrial and commercial nature placed under the joint authority of the Ministries of the Environment, Health, Industry, Research and Defense. It is the expert in safety research and specialized assessments into nuclear and radiological risk serving public authorities whose work is complementary to the ASN.
Its scope of activities includes:
environment and response,
human radiological protection,
research on the prevention of major accidents,
power reactor safety,
fuel cycle facility safety,
research installation safety,
waste management safety;
nuclear defense expertise.
National radioactive Waste Management Agency (ANDRA)
Created in 1991, the French National Agency for Radioactive Waste Management is a public industrial and commercial organization that operates independently of waste producers. It is responsible for the long-term management of radioactive waste produced in France under the supervision of the French Ministries for Energy, Research and the Environment. It can be compared to a certain extent to the Office for Nuclear Waste of the Department of Energy in the United States.
Andra also pursues industrial, research, and information activities as it designs and implements disposal solutions suited to each category of radioactive waste:
the collection, conditioning, disposal of radioactive waste from small producers (hospitals, research centers, industry),
specification of waste packages for disposal,
disposal in suited sites,
monitoring of closed disposal facilities,
research programs for long-lived and high level activity waste, especially through the operation of an underground research laboratory in a deep clay formation…
General Directorate for Energy and Climate (DGEC)
The General Directorate for Energy and Climate represents the government and is part of the Office of the Department for Ecology and Sustainable Development. It defines the French nuclear policy. The DGEC takes care of the energy supply, the security of supply, oil refining and logistics, nuclear industry, and coal and mines.
Consequently, its activities include:
the design and implement energy and raw material supply policy,
to ensure opening of electricity and gas markets,
track key energy and raw material sectors,
to oversee enterprises and public institutions in energy sector,
to ensure compliance with rules and regulations governing energy sector,
to participate in European and international energy projects and working groups,
to provide economic, environmental, and fiscal expertise on energy matters.
The Rise of Nuclear Power Generation in France. | 3.116173 |
Mexican America - Introduction
"Mexican America" is a sampling of objects from the collections of the National Museum of American History. The stories behind these objects reflect the history of the Mexican presence in the United States. They illustrate a fundamentally American story about the centuries-old encounter between distinct (yet sometimes overlapping) communities that have coexisted but also clashed over land, culture, and livelihood.
Who, where, and what is Mexico? Over time, the definitions and boundaries of Mexico have changed. The Aztec Empire and the area where Náhautl was spoken—today the region surrounding modern Mexico City—was known as Mexico. For 300 years, the Spanish colonizers renamed it New Spain.
When Mexico was reborn in 1821 as a sovereign nation, its borders stretched from California to Guatemala. It was a huge and ancient land of ethnically, linguistically, and economically diverse regions that struggled for national unity. Texas, (then part of the Mexican state of Coahuila y Tejas) was a frontier region far from the dense cities and fertile valleys of central Mexico, a place where immigrants were recruited from the United States. The immigrants in turn declared the Mexican territory an independent republic in 1836 (later a U.S. state), making the state the first cauldron of Mexican American culture. By 1853, the government of Mexico, the weaker neighbor of an expansionist United States, had lost what are today the states of California, Nevada, Utah, Arizona, New Mexico, Texas, and parts of Colorado and Wyoming. In spite of the imposition of a new border, the historical and living presence of Spaniards, Mexicans, indigenous peoples, and their mixed descendants remained a defining force in the creation of the American West.
“La América Mexicana” es una muestra conformada por objetos provenientes de las distintas colecciones del Museo Nacional de Historia Americana. Estos objetos reflejan la historia de la presencia mexicana en los Estados Unidos e ilustran una crónica fundamentalmente americana acerca del encuentro centenario entre comunidades diferentes que han coexistido, pero que también se han enfrentado, en la pugna por la tierra, la cultura y el sustento.
¿Quién, dónde y qué es México? Con el transcurso del tiempo, las definiciones y los límites de México han ido cambiando. Se conocía como México al Imperio Azteca y toda el área donde se hablaba náhuatl —actualmente la región circundante a la ciudad de México. Durante 300 años los colonizadores españoles se refirieron a ella como Nueva España. Cuando en 1821 México resurgió como una nación soberana, sus fronteras se extendían desde California a Guatemala. En ese entonces era un antiguo e inmenso territorio conformado por regiones étnica, lingüística y económicamente diversas que luchaban por adquirir unidad nacional. Texas (en ese entonces parte de los estados mexicanos de Coahuila y Tejas) era una región fronteriza lejos de las densas urbes y de los fértiles valles de México central, donde se reclutaban inmigrantes de los Estados Unidos. En el año 1836 este territorio mexicano se declaró como república independiente (y más tarde, estado de EE.UU.), convirtiéndose en el primer calderón de la cultura mexicoamericana. Hacia 1853, el gobierno de México, el vecino débil de un Estados Unidos en expansión, había perdido el territorio de los actuales estados de California, Nevada, Utah, Arizona, Nuevo México, Texas y partes de Colorado y Wyoming. A pesar de la imposición de un nuevo límite fronterizo, la presencia histórica y ocupacional de los españoles, mexicanos y pueblos indígenas, junto a sus descendientes mestizos, constituiría a lo largo del tiempo una influencia determinante para el desarrollo del Oeste Americano.
"Mexican America - Introduction" showing 1 items.
- This print depicts American forces attacking the fortress palace of Chapultepec on Sept. 13th, 1847. General Winfield Scott, in the lower left on a white horse, led the southern division of the U.S. Army that successfully captured Mexico City during the Mexican American War. The outcome of American victory was the loss of Mexico's northern territories, from California to New Mexico, by the terms set in the Treaty of Guadalupe Hidalgo. It should be noted that the two countries ratified different versions of the same peace treaty, with the United States ultimately eliminating provisions for honoring the land titles of its newly absorbed Mexican citizens. Despite notable opposition to the war from Americans like Abraham Lincoln, John Quincy Adams, and Henry David Thoreau, the Mexican-American War proved hugely popular. The United States' victory boosted American patriotism and the country's belief in Manifest Destiny.
- This large chromolithograph was first distributed in 1848 by Nathaniel Currier of Currier and Ives, who served as the "sole agent." The lithographers, Sarony & Major of New York (1846-1857) copied it from a painting by "Walker." Unfortunately, the current location of original painting is unknown, however, when the print was made the original painting was owned by a Captain B. S. Roberts of the Mounted Rifles. The original artist has previously been attributed to William Aiken Walker as well as to Henry A. Walke. William Aiken Walker (ca 1838-1921) of Charleston did indeed do work for Currier and Ives, though not until the 1880's and he would have only have been only 10 years old when this print was copyrighted. Henry Walke (1808/9-1896) was a naval combat artist during the Mexican American War who also worked with Sarony & Major and is best known for his Naval Portfolio.
- Most likely the original painting was done by James Walker (1819-1889) who created the "Battle of Chapultepec" 1857-1862 for the U.S. Capitol. This image differs from the painting commissioned for the U. S. Capitol by depicting the troops in regimented battle lines with General Scott in a more prominent position in the foreground. James Walker was living in Mexico City at the outbreak of the Mexican War and joined the American forces as an interpreter. He was attached to General Worth's staff and was present at the battles of Contreras, Churubusco, and Chapultepec. The original painting's owner, Captain Roberts was assigned General Winfield Scott to assist Walker with recreating the details of the battle of Chapultepec. When the painting was complete, Roberts purchased the painting. By 1848, James Walker had returned to New York and had a studio in New York City in the same neighborhood as the print's distributor Nathaniel Currier as well as the lithographer's Napoleon Sarony and Henry B. Major.
- This popular lithograph was one of several published to visually document the war while engaging the imagination of the public. Created prior to photography, these prints were meant to inform the public, while generally eliminating the portrayal of the more gory details. Historians have been able to use at least some prints of the Mexican War for study and to corroborate with the traditional literary forms of documentation. As an eyewitness, Walker could claim accuracy of detail within the narrative in his painting. The battle is presented in the grand, historic, heroic style with the brutality of war not portrayed. The print depiction is quite large for a chromo of the period. In creating the chromolithographic interpretation of the painting, Sarony & Major used at least four large stones to produce the print "in colours," making the most of their use of color. They also defined each figure with precision by outlining each in black. This print was considered by expert/collector Harry T. Peters as one of the finest ever produced by Sarony & Major.
- Currently not on view
- Date made
- associated date
- Currier, Nathaniel
- Scott, Winfield
- Sarony & Major
- Walker, James
- ID Number
- catalog number
- accession number
- Data Source
- National Museum of American History, Kenneth E. Behring Center | 4.078639 |
Octodon degus is generally considered endemic to west central Chile, where it inhabits the lower slopes of the Andes. Although some have argued that its range may extend north into Peru, this is not well supported. It is common in the international pet trade, however, and is often used in laboratory studies outside of its native range. (Contreras, et al., 1987; Woods and Boraker, 1975)
Octodon degus inhabits a mediterranean-type semi-arid shrubland ecosystem called "matorral", which is found on the western slopes of the Andes between 28 and 35 degrees south latitude. Further north the climate becomes too arid to support this plant community, and further south it is too wet. Degus appear to be limited to elevations below 1200 meters, both by the distribution of their habitat and by their intolerance of low oxygen partial pressure. Degus are well able to inhabit lands influenced by cattle grazing, and are agricultural pests in some areas. (Contreras, et al., 1987; Fulk, 1976)
Octodon degus superficially resembles a gerbil, but is much larger. Degus typically weigh between 170 and 300 g, and measure between 325 and 440 mm in length, including the tail. The fur is yellow-brown on the back and head, and the underparts and feet are cream colored. There is a pale band around the eye and, in some individuals, the neck. The tail is moderately long and conspicuously tufted. The ears are large and darkly pigmented. The fifth digit is reduced, and on the forefeet it has a nail instead of a claw. The cheekteeth are hypsodont and their biting surfaces resemble a figure of eight. Sexes are difficult to distinguish, but males tend to be about 10% larger than females. Pups are born furred and able to see, and begin exploring within hours of birth. Octodon degus can be distinguished from the two other members of the genus Octodon by slight differences in dental morphology. It is also smaller than its relatives and its tail is said to be more noticeably tufted. (Fulk, 1976; Lee, 2004)
During the annual breeding season, male-male aggression temporarily increases. Males exclude other males from their burrow and monopolize the females (usually 2 to 4) who live there. Dustbathing and urine marking may be used in the defense of territory by both sexes, but these behaviors particularly increase in the male during the breeding season. Courting males often engage in mutual grooming with females, and frequently perform a courtship ritual which involves wagging of the tail and trembling of the body. The male then raises a hind leg and sprays urine onto the female. This may serve to familiarize her with his scent and perhaps make her more receptive to his advances in the future. Receptive females may sometimes enurinate males in a similar fashion. Related female degus may nurse each other's young. (Ebensperger and Caiozzi, 2002; Fulk, 1976; Kleiman, 1974; Soto-Gamboa, 2005)
In the wild degus tend to breed once per year. The breeding season usually begins in late May (autumn in Chile), and the young are conceived in late winter to early spring (September to October). In wet years, degus may produce second litters. It has been suggested that degus may be induced ovulators, but this has not been established for certain. There is also some evidence that male reproductive organs may be sensitive to changes in photoperiod. The gestation period is 90 days, and litter size is typically 4-6 pups. The young are precocial. They are born with fur and teeth; their eyes are open and they are able to move about the nest on their own. Pups are weaned at 4 to 5 weeks, and become sexually mature between 12 and 16 weeks of age. Degus do not reach adult size until about 6 months of age, however, and they generally live in same-sex social groups until they are about 9 months old and their first breeding season occurs. It has been reported that pups raised in isolation in the laboratory experience severe neural and behavioral abnormalities. (Ebensperger and Hurtado, 2005; Lee, 2004; Woods and Boraker, 1975)
Before conception can occur, the male degu must invest considerable energy in the defense of his territory and harem from other males. The female subsequently expends considerable energy in gestation and lactation. The pregnancy is relatively long for a rodent, and the young are born well developed. After birth, both parents protect and provision the pups. Degus nest communally, and groups of related females nurse one another's young. In the laboratory, the female remains close to the pups until two weeks after birth, and males have been observed to huddle with the young during this period without instances of infanticide. In the wild, male degus may spend as much time feeding and huddling with the young as females do. Pups begin to eat solid food at about two weeks of age, and venture out of the burrow at three weeks. Upon weaning at four to six weeks, the pups are able to live independently of the parents and form same-sex social groups until their first breeding season. (Ebensperger and Hurtado, 2005; Fulk, 1976; Lee, 2004; Woods and Boraker, 1975)
In laboratory conditions, degus typically live five to eight years.
Degus are social and tend to live in groups of one to two males and two to five related females. Females participate in rearing on another's young. Groups maintain territories throughout much of the year. Degus are semi-fossorial, digging extensive communal burrow systems. These burrows are often shared by Bennett's chinchilla rat (Abrocoma bennettii). Degus feed exclusively above ground, however, and have been observed climbing into the low branches of shrubs while foraging. Dustbathing is an important social behavior among degus. Groups repeatedly mark favorite wallows with urine and anal gland secretions. This may help the group identify each other by scent as well as delineating territorial boundaries. Degus are mainly diurnal, and are most active during the morning and evening. (Ebensperger, et al., 2004; Fulk, 1976; Woods and Boraker, 1975)
Fulk (1976) estimated that social groups of degus occupy home areas of roughly 200 square meters, and that their density is about 75 degus per hectare. This may be an underestimate, however, due to the trapping methods used. (Fulk, 1976)
Degus have well-developed sight, smell, and hearing. They are highly vocal and use various calls to communicate with one another, including alarm calls, mating calls, and communication between parents and young. Vision is very important in avoidance of predators and in foraging. It has been shown that degus are able to see ultraviolet wavelengths, and that their urine reflects in the UV range when fresh. It has therefore been suggested that degus' urine scent marks are also visual cues. These scent marks are also used as dust wallows, allowing members of a social group to identify each other by scent. (Chavez, et al., 2003; Fulk, 1976; Woods and Boraker, 1975)
Degus are generalist herbivores. They feed on the leaves, bark, and seeds of shrubs and forbs. Among their favorite foods are the bark of Cestrum palqui and Mimosa cavenia, leaves and bark of Proustia cuneifolia, Atriplex repunda, and Acacia caven, annuals such as Erodium cicutarum when in season, green grasses, and thistle seeds. Degus choose food items that reduce fiber and increase nitrogen and moisture in the diet, and thus prefer young leaves and avoid woodier shrubs. Degus rely on microbial fermentation in their enlarged cecum (they are "hindgut fermenters") to digest their food. They reingest a large percentage of their feces, usually during the night. This allows them to maximize their digestion. Degus store food in the winter, and it has been reported that they occasionally eat meat in old age. (Gutierrez and Bozinovic, 1998; Kenagy, et al., 1999; Veloso and Kenagy, 2005; Woods and Boraker, 1975)
Octodon degus is subject to predation by larger mammals such as culpeo foxes (Lycalopex culpaeus), and from the air by raptors such as barn owls (Tyto alba), short-eared owls (Asio flammeus), and black-chested buzzard eagles (Geranoaetus melanoleucus). Degus use vigilance and cover to avoid predators. Their pelage is also counter-shaded and matches the soil color, which reduces visibility to predators. Degus live socially and use alarm calls to warn others of danger. When a predator is spotted, they take cover in shrubby areas and may retreat to the communal burrow. (Ebensperger and Wallem, 2002; Woods and Boraker, 1975)
Octodon degus affects the plant community in its habitat by selective browsing. Degus behaviorally reduce the fiber content of their diet, preferrentially eating shrubs such as Adesmia bedwellii, Baccharis paniculata, and Chenopodium petioare, which are less fibrous and less thorny than others. These species have been shown to increase their foliage area upon exclusion of degus. As degus are very common, they are themselves an important food source for their predators. (Gutierrez and Bozinovic, 1998)
Degus often live in association with Bennett's chinchilla rats (Abrocoma bennettii). The two species are known to share burrow systems and have even been observed in the same chamber within a burrow. This is believed to be a mutualistic relationship, but it is not well understood. (Fulk, 1976; Woods and Boraker, 1975)
Degus are frequently kept as pets, and are used extensively in laboratory research. Because they are largely diurnal, they are useful in research on circadian rhythms, and their intolerance of sugars makes them ideal models for diabetes research. (Lee, 2004)
Degus are significant agricultural pests in some areas. They take advantage of cultivated prickly pear cactus, wheat, vineyards, and orchards as abundant food sources, and can do considerable damage. They are also known to host three species of parasites that can infect humans. (Fulk, 1976)
Tanya Dewey (editor), Animal Diversity Web.
Mary Hejna (author), University of Michigan-Ann Arbor, Phil Myers (editor, instructor), Museum of Zoology, University of Michigan-Ann Arbor.
living in the southern part of the New World. In other words, Central and South America.
uses sound to communicate
living in landscapes dominated by human agriculture.
having body symmetry such that the animal can be divided in one plane into two mirror-image halves. Animals with bilateral symmetry have dorsal and ventral sides, as well as anterior and posterior ends. Synapomorphy of the Bilateria.
Found in coastal areas between 30 and 40 degrees latitude, in areas with a Mediterranean climate. Vegetation is dominated by stands of dense, spiny shrubs with tough (hard or waxy) evergreen leaves. May be maintained by periodic fire. In South America it includes the scrub ecotone between forest and paramo.
uses smells or other chemicals to communicate
helpers provide assistance in raising young that are not their own
an animal that mainly eats the dung of other animals
active at dawn and dusk
having markings, coloration, shapes, or other features that cause an animal to be camouflaged in its natural environment; being difficult to see or otherwise detect.
animals that use metabolically generated heat to regulate body temperature independently of ambient temperature. Endothermy is a synapomorphy of the Mammalia, although it may have arisen in a (now extinct) synapsid ancestor; the fossil record does not distinguish these possibilities. Convergent in birds.
an animal that mainly eats leaves.
Referring to a burrowing life-style or behavior, specialized for digging or burrowing.
an animal that mainly eats seeds
An animal that eats mainly plants or parts of plants.
offspring are produced in more than one group (litters, clutches, etc.) and across multiple seasons (or other periods hospitable to reproduction). Iteroparous animals must, by definition, survive over multiple seasons (or periodic condition changes).
having the capacity to move from one place to another.
the area in which the animal is naturally found, the region in which it is endemic.
the business of buying and selling animals for people to keep in their homes as pets.
having more than one female as a mate at one time
specialized for leaping or bounding locomotion; jumps or hops.
communicates by producing scents from special gland(s) and placing them on a surface whether others can smell or taste them
breeding is confined to a particular season
remains in the same area
reproduction that includes combining the genetic contribution of two individuals, a male and a female
associates with others of its species; forms social groups.
places a food item in a special place to be eaten later. Also called "hoarding"
uses touch to communicate
that region of the Earth between 23.5 degrees North and 60 degrees North (between the Tropic of Cancer and the Arctic Circle) and between 23.5 degrees South and 60 degrees South (between the Tropic of Capricorn and the Antarctic Circle).
Living on the ground.
defends an area within the home range, occupied by a single animals or group of animals of the same species and held through overt defense, display, or advertisement
uses sight to communicate
reproduction in which fertilization and development take place within the female body and the developing embryo derives nourishment from the female.
young are relatively well-developed when born
Chavez, A., F. Bozinovic, L. Peichl, A. Palacios. 2003. Retinal spectral sensitivity, fur coloration, and urine reflectance in the genus Octodon (Rodentia): implications for visual ecology. Investigative Opthalmology & Visual Science, 44/5: 2290-2296.
Contreras, L., J. Torres-Mura, J. Yanez. 1987. Biogeography of Octodontid rodents: An eco-evolutionary hypothesis. Fieldiana: Zoology, New Series, 39: 401-411.
Ebensperger, L., F. Bozinovic. 2000. Energetics and burrowing behaviour in the semifossorial degu Octadon degus (Rodentia: Octodontidae). Journal of Zoology, 252: 179-186.
Ebensperger, L., A. Caiozzi. 2002. Male degus, Octodon degus, modify their dustbathing behavior in response to social familiarity of previous dustbathing marks. Revista Chilena de Historia Natural, 75: 157-163.
Ebensperger, L., M. Hurtado. 2005. On the relationship between herbaceous cover and vigilance activity of degus (Octodon degus). Ethology, 111/6: 593-608.
Ebensperger, L., M. Hurtado. 2005. Seasonal changes in the time budget of degus, Octadon degus.. Behaviour, 142: 91-112.
Ebensperger, L., M. Hurtado, M. Soto-Gamboa, E. Lacey, A. Chang. 2004. Communal nesting and kinship in degus (Octodon degus). Naturwissenschaften, 91: 391-395.
Ebensperger, L., P. Wallem. 2002. Grouping increases the ability of the social rodent, Octodon degus, to detect predators when using exposed microhabitats. Oikos, 98: 491-497.
Fulk, G. 1976. Notes on the activity, reproduction, and social behavior of Octodon degus. Journal of Mammalogy, 57/3: 495-505.
Gutierrez, J., F. Bozinovic. 1998. Diet selection in captivity by a generalist herbivorous rodent (Octodon degus) from the Chilean coastal desert. Journal of Arid Environments, 39: 601-607.
Kenagy, G., R. Nespolo, R. Vasquez, F. Bozinovic. 2002. Daily and seasonal limits of time and temperature to activity of degus. Revista Chilena de Historia Natural, 75: 567-581.
Kenagy, G., C. Veloso, F. Bozinovic. 1999. Daily rhythms of food intake and feces reingestion in the degu, an herbivorous Chilean rodent: optimizing digestion through coprophagy. Physiological and Biochemical Zoology, 72/1: 78-86.
Kleiman, D. 1974. Patterns of behaviour in hystricomorph rodents. Symposium of the Zoological Society (London), 34: 171-209.
Lee, T. 2004. Octodon degus: A diurnal, social, and long-lived rodent. ILAR Journal, 45/1: 14-24.
Soto-Gamboa, M., M. Villalon, F. Bozinovic. 2005. Social cues and hormone levels in male Octadon degus (Rodentia): a field test of the Challange Hypothesis. Hormones and Behavior, 47/3: 311-318.
Soto-Gamboa, M. 2005. Free and total testosterone levels in field males of Octodon degus (Rodentia, Octodontidae): accuracy of the hormonal regulation of behavior. Revista Chilena de Historia Natural, 78/2: 229-238.
Tokimoto, N., K. Okanoya. 2004. Spontaneous construction of "Chines boxes" by Degus (Octodon degus): A rudiment of recursive intelligence?. Japanese Psychological Research, 46/3: 255-261.
Veloso, C., G. Kenagy. 2005. Temporal dynamics of milk composition of the precocial caviomorph Octodon degus (Rodentia : Octodontidae). Revista Chilena de Historia Natural, 78/2: 247-252.
Woods, C., D. Boraker. 1975. Octodon degus. Mammalian Species, 67: 1-5. | 3.060866 |
Details of Glycemic Index (GI)
The GI Scale
The glycemic index uses a scale from 1 to 100, which indicates the rate at which 50 grams of carbohydrate in a particular food is absorbed into the bloodstream as blood-sugar. The main reference food (rated 100) is glucose.
GI Rating Categories
The glycemic index divides carbohydrate
foods into three categories:
GI Food Testing is Ongoing
Not all foods have been given a GI value, although most food-types are covered. However, due to the way GI is measured using volunteer subjects, results can vary, so GI values for some specific foods are not yet uniformly established.
GI - Diabetes and Weight Control
Although the glycemic index was first designed to assist diabetes patients manage their blood-sugar levels, dietitians and weight experts now use it as a tool to help treat obesity, food cravings and appetite swings, and improve eating habits.
Both the type AND quantity of carbohydrate in our food influence the rise in blood glucose. But the glycemic index only rates a standard 50 gram serving size of digestible carbohydrate in a particular food, which may not be appropriate for all foods. For example, foods whose serving size contains only a small amount of carbohydrate may in practice be better for blood sugar control than foods whose normal serving size contains a large amount of carbs. Therefore, to provide a more meaningful GI-rating system, researchers at Harvard University invented the term Glycemic Load, which applies the glycemic index to normal food serving sizes.
OBESITY, OVERWEIGHT and | 3.740911 |
- published: 19 Mar 2013
- views: 42
- author: T.A. B
possibly testing on weans, that worries me http://www.bbc.co.uk/news/world-us-canada-21849808.
A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe, its toxins or one of its surface proteins. The agent stimulates the body's immune system to recognize the agent as foreign, destroy it, and "remember" it, so that the immune system can more easily recognize and destroy any of these microorganisms that it later encounters.
Vaccines can be prophylactic (example: to prevent or ameliorate the effects of a future infection by any natural or "wild" pathogen), or therapeutic (e.g. vaccines against cancer are also being investigated; see cancer vaccine).
The term vaccine derives from Edward Jenner's 1796 use of cow pox (Latin variola vaccinia, adapted from the Latin vaccīn-us, from vacca, cow), to inoculate humans, providing them protection against smallpox.
Vaccines do not guarantee complete protection from a disease. Sometimes, this is because the host's immune system simply does not respond adequately or at all. This may be due to a lowered immunity in general (diabetes, steroid use, HIV infection, age) or because the host's immune system does not have a B cell capable of generating antibodies to that antigen.
Even if the host develops antibodies, the human immune system is not perfect and in any case the immune system might still not be able to defeat the infection immediately. In this case, the infection will be less severe and heal faster.
Adjuvants are typically used to boost immune response. Most often aluminium adjuvants are used, but adjuvants like squalene are also used in some vaccines and more vaccines with squalene and phosphate adjuvants are being tested. Larger doses are used in some cases for older people (50–75 years and up), whose immune response to a given vaccine is not as strong.
The efficacy or performance of the vaccine is dependent on a number of factors:
When a vaccinated individual does develop the disease vaccinated against, the disease is likely to be milder than without vaccination.
The following are important considerations in the effectiveness of a vaccination program:
In 1958 there were 763,094 cases of measles and 552 deaths in the United States. With the help of new vaccines, the number of cases dropped to fewer than 150 per year (median of 56). In early 2008, there were 64 suspected cases of measles. 54 out of 64 infections were associated with importation from another country, although only 13% were actually acquired outside of the United States; 63 of these 64 individuals either had never been vaccinated against measles, or were uncertain whether they had been vaccinated.
Vaccines are dead or inactivated organisms or purified products derived from them.
There are several types of vaccines in use. These represent different strategies used to try to reduce risk of illness, while retaining the ability to induce a beneficial immune response.
Some vaccines contain killed, but previously virulent, micro-organisms that have been destroyed with chemicals, heat, radioactivity or antibiotics. Examples are the influenza vaccine, cholera vaccine, bubonic plague vaccine, polio vaccine, hepatitis A vaccine, and rabies vaccine.
Some vaccines contain live, attenuated microorganisms. Many of these are live viruses that have been cultivated under conditions that disable their virulent properties, or which use closely related but less dangerous organisms to produce a broad immune response. Although most attenuated vaccines are viral, some are bacterial in nature. They typically provoke more durable immunological responses and are the preferred type for healthy adults. Examples include the viral diseases yellow fever, measles, rubella, and mumps and the bacterial disease typhoid. The live Mycobacterium tuberculosis vaccine developed by Calmette and Guérin is not made of a contagious strain, but contains a virulently modified strain called "BCG" used to elicit an immune response to the vaccine. The live attenuated vaccine containing strain Yersinia pestis EV is used for plague immunization. Attenuated vaccines have some advantages and disadvantages. They have the capacity of transient growth so they give prolonged protection, and no booster dose is required. But they may get reverted to the virulent form and cause the disease.
Toxoid vaccines are made from inactivated toxic compounds that cause illness rather than the micro-organism. Examples of toxoid-based vaccines include tetanus and diphtheria. Toxoid vaccines are known for their efficacy. Not all toxoids are for micro-organisms; for example, Crotalus atrox toxoid is used to vaccinate dogs against rattlesnake bites.
Protein subunit – rather than introducing an inactivated or attenuated micro-organism to an immune system (which would constitute a "whole-agent" vaccine), a fragment of it can create an immune response. Examples include the subunit vaccine against Hepatitis B virus that is composed of only the surface proteins of the virus (previously extracted from the blood serum of chronically infected patients, but now produced by recombination of the viral genes into yeast), the virus-like particle (VLP) vaccine against human papillomavirus (HPV) that is composed of the viral major capsid protein, and the hemagglutinin and neuraminidase subunits of the influenza virus. Subunit vaccine is being used for plague immunization.
Conjugate – certain bacteria have polysaccharide outer coats that are poorly immunogenic. By linking these outer coats to proteins (e.g. toxins), the immune system can be led to recognize the polysaccharide as if it were a protein antigen. This approach is used in the Haemophilus influenzae type B vaccine.
A number of innovative vaccines are also in development and in use:
While most vaccines are created using inactivated or attenuated compounds from micro-organisms, synthetic vaccines are composed mainly or wholly of synthetic peptides, carbohydrates or antigens.
Vaccines may be monovalent (also called univalent) or multivalent (also called polyvalent). A monovalent vaccine is designed to immunize against a single antigen or single microorganism. A multivalent or polyvalent vaccine is designed to immunize against two or more strains of the same microorganism, or against two or more microorganisms. In certain cases a monovalent vaccine may be preferable for rapidly developing a strong immune response.
The immune system recognizes vaccine agents as foreign, destroys them, and "remembers" them. When the virulent version of an agent comes along the body recognizes the protein coat on the virus, and thus is prepared to respond, by (1) neutralizing the target agent before it can enter cells, and (2) by recognizing and destroying infected cells before that agent can multiply to vast numbers.
When two or more vaccines are mixed together in the same formulation, the two vaccines can interfere. This most frequently occurs with live attenuated vaccines, where one of the vaccine components is more robust than the others and suppresses the growth and immune response to the other components. This phenomenon was first noted in the trivalent Sabin polio vaccine, where the amount of serotype 2 virus in the vaccine had to be reduced to stop it from interfering with the "take" of the serotype 1 and 3 viruses in the vaccine. This phenomenon has also been found to be a problem with the dengue vaccines currently being researched,[when?] where the DEN-3 serotype was found to predominate and suppress the response to DEN-1, -2 and -4 serotypes.
Vaccines have contributed to the eradication of smallpox, one of the most contagious and deadly diseases known to man. Other diseases such as rubella, polio, measles, mumps, chickenpox, and typhoid are nowhere near as common as they were a hundred years ago. As long as the vast majority of people are vaccinated, it is much more difficult for an outbreak of disease to occur, let alone spread. This effect is called herd immunity. Polio, which is transmitted only between humans, is targeted by an extensive eradication campaign that has seen endemic polio restricted to only parts of four countries (Afghanistan, India, Nigeria and Pakistan). The difficulty of reaching all children as well as cultural misunderstandings, however, have caused the anticipated eradication date to be missed several times.
In order to provide best protection, children are recommended to receive vaccinations as soon as their immune systems are sufficiently developed to respond to particular vaccines, with additional "booster" shots often required to achieve "full immunity". This has led to the development of complex vaccination schedules. In the United States, the Advisory Committee on Immunization Practices, which recommends schedule additions for the Centers for Disease Control and Prevention, recommends routine vaccination of children against: hepatitis A, hepatitis B, polio, mumps, measles, rubella, diphtheria, pertussis, tetanus, HiB, chickenpox, rotavirus, influenza, meningococcal disease and pneumonia. The large number of vaccines and boosters recommended (up to 24 injections by age two) has led to problems with achieving full compliance. In order to combat declining compliance rates, various notification systems have been instituted and a number of combination injections are now marketed (e.g., Pneumococcal conjugate vaccine and MMRV vaccine), which provide protection against multiple diseases.
Besides recommendations for infant vaccinations and boosters, many specific vaccines are recommended at other ages or for repeated injections throughout life—most commonly for measles, tetanus, influenza, and pneumonia. Pregnant women are often screened for continued resistance to rubella. The human papillomavirus vaccine is recommended in the U.S. (as of 2011) and UK (as of 2009). Vaccine recommendations for the elderly concentrate on pneumonia and influenza, which are more deadly to that group. In 2006, a vaccine was introduced against shingles, a disease caused by the chickenpox virus, which usually affects the elderly.
Sometime during the 1770s Edward Jenner heard a milkmaid boast that she would never have the often-fatal or disfiguring disease smallpox, because she had already had cowpox, which has a very mild effect in humans. In 1796, Jenner took pus from the hand of a milkmaid with cowpox, inoculated an 8-year-old boy with it, and six weeks later variolated the boy's arm with smallpox, afterwards observing that the boy did not catch smallpox. Further experimentation demonstrated the efficacy of the procedure on an infant. Since vaccination with cowpox was much safer than smallpox inoculation, the latter, though still widely practiced in England, was banned in 1840. Louis Pasteur generalized Jenner's idea by developing what he called a rabies vaccine, and in the nineteenth century vaccines were considered a matter of national prestige, and compulsory vaccination laws were passed.
The twentieth century saw the introduction of several successful vaccines, including those against diphtheria, measles, mumps, and rubella. Major achievements included the development of the polio vaccine in the 1950s and the eradication of smallpox during the 1960s and 1970s. Maurice Hilleman was the most prolific of the developers of the vaccines in the twentieth century. As vaccines became more common, many people began taking them for granted. However, vaccines remain elusive for many important diseases, including malaria and HIV.
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Opposition to vaccination, from a wide array of vaccine critics, has existed since the earliest vaccination campaigns. Although the benefits of preventing suffering and death from serious infectious diseases greatly outweigh the risks of rare adverse effects following immunization, disputes have arisen over the morality, ethics, effectiveness, and safety of vaccination. Some vaccination critics say that vaccines are ineffective against disease or that vaccine safety studies are inadequate. Some religious groups do not allow vaccination, and some political groups oppose mandatory vaccination on the grounds of individual liberty. In response, concern has been raised that spreading unfounded information about the medical risks of vaccines increases rates of life-threatening infections, not only in the children whose parents refused vaccinations, but also in other children, perhaps too young for vaccines, who could contract infections from unvaccinated carriers (see herd immunity).
One challenge in vaccine development is economic: many of the diseases most demanding a vaccine, including HIV, malaria and tuberculosis, exist principally in poor countries. Pharmaceutical firms and biotechnology companies have little incentive to develop vaccines for these diseases, because there is little revenue potential. Even in more affluent countries, financial returns are usually minimal and the financial and other risks are great.
Most vaccine development to date has relied on "push" funding by government, universities and non-profit organizations. Many vaccines have been highly cost effective and beneficial for public health. The number of vaccines actually administered has risen dramatically in recent decades.[when?] This increase, particularly in the number of different vaccines administered to children before entry into schools may be due to government mandates and support, rather than economic incentive.
The filing of patents on vaccine development processes can also be viewed as an obstacle to the development of new vaccines. Because of the weak protection offered through a patent on the final product, the protection of the innovation regarding vaccines is often made through the patent of processes used on the development of new vaccines as well as the protection of secrecy.
Vaccine production has several stages. First, the antigen itself is generated. Viruses are grown either on primary cells such as chicken eggs (e.g., for influenza), or on continuous cell lines such as cultured human cells (e.g., for hepatitis A). Bacteria are grown in bioreactors (e.g., Haemophilus influenzae type b). Alternatively, a recombinant protein derived from the viruses or bacteria can be generated in yeast, bacteria, or cell cultures. After the antigen is generated, it is isolated from the cells used to generate it. A virus may need to be inactivated, possibly with no further purification required. Recombinant proteins need many operations involving ultrafiltration and column chromatography. Finally, the vaccine is formulated by adding adjuvant, stabilizers, and preservatives as needed. The adjuvant enhances the immune response of the antigen, stabilizers increase the storage life, and preservatives allow the use of multidose vials. Combination vaccines are harder to develop and produce, because of potential incompatibilities and interactions among the antigens and other ingredients involved.
Vaccine production techniques are evolving. Cultured mammalian cells are expected to become increasingly important, compared to conventional options such as chicken eggs, due to greater productivity and low incidence of problems with contamination. Recombination technology that produces genetically detoxified vaccine is expected to grow in popularity for the production of bacterial vaccines that use toxoids. Combination vaccines are expected to reduce the quantities of antigens they contain, and thereby decrease undesirable interactions, by using pathogen-associated molecular patterns.
In 2010, India produced 60 percent of world's vaccine worth about $900 million.
Many vaccines need preservatives to prevent serious adverse effects such as Staphylococcus infection that, in one 1928 incident, killed 12 of 21 children inoculated with a diphtheria vaccine that lacked a preservative. Several preservatives are available, including thiomersal, phenoxyethanol, and formaldehyde. Thiomersal is more effective against bacteria, has better shelf life, and improves vaccine stability, potency, and safety, but in the U.S., the European Union, and a few other affluent countries, it is no longer used as a preservative in childhood vaccines, as a precautionary measure due to its mercury content. Although controversial claims have been made that thiomersal contributes to autism, no convincing scientific evidence supports these claims.
There are several new delivery systems in development[when?] that will hopefully make vaccines more efficient to deliver. Possible methods include liposomes and ISCOM (immune stimulating complex).
The latest developments[when?] in vaccine delivery technologies have resulted in oral vaccines. A polio vaccine was developed and tested by volunteer vaccinations with no formal training; the results were positive in that the ease of the vaccines increased. With an oral vaccine, there is no risk of blood contamination. Oral vaccines are likely to be solid which have proven to be more stable and less likely to freeze; this stability reduces the need for a "cold chain": the resources required to keep vaccines within a restricted temperature range from the manufacturing stage to the point of administration, which, in turn, may decrease costs of vaccines. A microneedle approach, which is still in stages of development, uses "pointed projections fabricated into arrays that can create vaccine delivery pathways through the skin".
A nanopatch is a needle free vaccine delivery system which is under development. A stamp-sized patch similar to an adhesive bandage contains about 20,000 microscopic projections per square inch. When worn on the skin, it will deliver vaccine directly to the skin, which has a higher concentration of immune cells than that in the muscles, where needles and syringes deliver. It thus increases the effectiveness of the vaccination using a lower amount of vaccine used in traditional syringe delivery system.
The use of plasmids has been validated in preclinical studies as a protective vaccine strategy for cancer and infectious diseases. However, in human studies this approach has failed to provide clinically relevant benefit. The overall efficacy of plasmid DNA immunization depends on increasing the plasmid's immunogenicity while also correcting for factors involved in the specific activation of immune effector cells.
Vaccinations of animals are used both to prevent their contracting diseases and to prevent transmission of disease to humans. Both animals kept as pets and animals raised as livestock are routinely vaccinated. In some instances, wild populations may be vaccinated. This is sometimes accomplished with vaccine-laced food spread in a disease-prone area and has been used to attempt to control rabies in raccoons.
Where rabies occurs, rabies vaccination of dogs may be required by law. Other canine vaccines include canine distemper, canine parvovirus, infectious canine hepatitis, adenovirus-2, leptospirosis, bordatella, canine parainfluenza virus, and Lyme disease among others.
Vaccine development has several trends:
Principles that govern the immune response can now be used in tailor-made vaccines against many noninfectious human diseases, such as cancers and autoimmune disorders. For example, the experimental vaccine CYT006-AngQb has been investigated as a possible treatment for high blood pressure. Factors that have impact on the trends of vaccine development include progress in translatory medicine, demographics, regulatory science, political, cultural, and social responses.
|Modern Vaccine and Adjuvant Production and Characterization, Genetic Engineering & Biotechnology News|
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"Helplessness" and "confusion" are words that easily come to mind when the issue of sick building syndrome is mentioned. It is a problem that does not have a regulatory solution, and is bound with engineering, medicine and emotions that will challenge the best of school administrators.
A careful management style and knowledgeable use of technologies in medicine, toxicology and property maintenance are a school administrator's best allies in preparing to deal with or prevent this new generation of health and safety challenges.
Defining sick building syndrome There is no regulatory definition for sick building syndrome. Although it often relates to indoor-air-quality problems, it simply means that the environment of a building is inspiring complaints of discomfort and/or disease.
Fundamentally, the causes of sick buildings relate to architecture and engineering patterns institutionalized in school construction following World War II. Schools of glass, rock and wood, with high ceilings, cross-ventilation via a transom over the door, and windows and radiators that could be adjusted by teachers no longer were built. These schools were being replaced with new, factory-like buildings featuring a temperamental, eccentric system of master controls for indoor environment. Buildings were constructed with no regard to the environment around them or to people within the property. Today, allowing for the ambiguity in defining sick buildings, somewhere between 1-in-5 and 1-in-15 school facilities are in a situation where discomfort and disease can be attributed to operations of the building.
Health symptoms in a sick building are highly variable, but generally split into three categories:
-Radical reaction--a number of people clearly and suddenly ill. This usually involves limited air exchange combined with a "smoking gun," which can include a new chemical cleaner, misbatched chlorine in a pool area, a weather inversion preventing a kiln from venting properly or a failure of a mechanical air-exchange system.
-Unhealthy atmosphere--many people experiencing ongoing subtle illness or discomfort. The most common symptoms involve the dehydration of sensitive tissue, including sore eyes, throat or nasal membranes; a feeling of lethargy; a higher incidence of upper-respiratory infection; asthmatic reactions; low-grade headaches; and a continuum of muscle pain and general discomfort among building occupants. Much of this relates to oxygen deprivation typically caused by oxygen being displaced by other compounds, and occasionally by infestation of microbes as a result of excessive moisture remaining within the property.
-Hypersensitive reaction or multiple chemical sensitivity reaction--one or two individuals extremely ill. This can result if even tiny exposures occur to anyone that has a highly sensitive reaction to certain chemicals. Typically, these complaints should be viewed as warnings that some low-level toxin is in the area.
Although sick building syndrome usually relates to the general nature of the building itself, there are some specifics that account for most indoor-air problems:
*Combustibles; any possible introduction of carbon monoxide. *Moisture as it may relate to mold (look for growths on drywall). *Moisture as it may relate to airborne infectious agents (standing water and consequent growths). *Volatile organic compounds (VOCs), usually cleaning agents or building materials, which may give off unpleasant, sometimes toxic gases. *Formaldehydes in new carpet, pressed wood or other building products. *Any new or newly exposed particleboard. *Applied poisons (pesticides, insecticides, rodenticides, herbicides).
A proactive approach Administrators are dealing with a generation of post-World War II properties prone to indoor-air-quality problems, particularly buildings constructed or remodeled during the 1970s energy crisis. A school district should take several steps before a problem strikes. First, initiate patterns for preventing air-quality problems. Second, establish baseline information that will profile the building to facilitate an efficient, inexpensive and confidence-inspiring response. Building occupants and the community need to see a clear and confident administrative approach should a problem arise in the future.
The proactive investigation of the building should involve a limited amount of basic testing, particularly a professional review of the microbial matrix within the building--the number of colony-forming units or what kinds of microbes presently are nesting in the building. Understanding what is living in the ambient air can help administrators understand if there is a problem or, more importantly, can help to quickly isolate the exact nature of a problem.
Similarly, administrators should consider hiring an outside contractor to review how air-handling and mechanical-engineering systems are managed. A knowledgeable person should walk the area and observe the mechanical systems to see how the filtering system, the air-dispersion system and the air-dilution patterns of the building are operating. Finally, a reliable epidemiological profile of comparative absenteeism should be archived.
Administrators also need to be ready to implement a smooth, confidence-building reporting system for occupants regarding air-quality or sick-building concerns. How fast and capably the district responds can be the key to getting the issue under control. The costs for responding to indoor-air problems decrease dramatically if there is baseline data and a plan in place. | 3.409944 |
"GOT NOTHING BUT BLUE SKIES"
It is September 19,1783. The place, Lyons, France. Preparations are being made for a journey. A journey that will eventually take man from his secure environment of terra firma, and place him in a hostile environment called the atmosphere. The vehicle to be used is a hot air balloon. The brainchild behind this trek is a wealthy paper maker named Joseph Montgolfier. There has been much speculation over just how Montgolfier made the discovery of the hot air balloon. The most commonly-believed story is that his wife was standing too close to a fire and that the smoke caused her skirt to be inflated and lifted above her knees. This caused Montgolfier to wonder-if this smoke, and its magical lifting powers, could be captured in a very large container, it might rise and lift a passenger along with it.
So, Montgolfier went about building the first hot air balloon. In 1783,
not much was known about the atmosphere and its effects on human beings.
Upon examination of the occupants for any ill effects caused by this lofty height, it was discovered that the duck had a broken wing. Could this have been an effect of exposure to altitude? Actually, several observers noted that as the balloon left the ground, the sheep had an anxiety attack and kicked the duck. Montgolfier reasoned that it would be safe for humans to ascend to altitude. So on November 21, 1783, Jean Francois Pilatre de Rozier (a surgeon) became the first aeronaut and flight surgeon. Over 200 years have passed since that first flight. Technology has allowed us to ascend through the atmosphere and into space, but the hazards of high altitude flight (hypoxia, altitude-induced decompression sickness, and trapped gases) will always be present. That is because humans are best suited to live in what is known as the "physiological efficient zone". This zone extends from sea level to 12,000 feet. When humans are exposed to altitudes above this zone, they are subjected to physiological hazards beyond their natural ability to adapt.
One thing to keep in mind is that everything that occupies space and exerts weight is considered to be matter. All matter is made up of atoms and molecules in varying densities. These particles within the matter are kinetic and in constant motion. The slower the motion of the particles, the more dense the matter becomes. Also, as the particles are pushed closer together, the matter also becomes more dense. The best way to slow down kinetic molecules is to cool the matter. The best way to get them to move closer together is to add pressure to the matter. Inversely, when you remove the pressure or heat any material, the molecules within the material moves faster and further apart, thus making the material less dense.
The least dense form of matter is, of course, gas. If a gas is cooled and compressed, at some point it will become a liquid. If that liquid is then cooled further, then at some point it will become a solid. Also, when you take the pressure off any gas or liquid, that material will grow less dense and expand. This is essentially what happens to the gaseous molecules of our atmosphere.
Our atmosphere contains approximately 79% nitrogen and 21% oxygen, a constant ratio until you reach an altitude of about 270,000 feet. So the question that always comes up is; "If I have 21% oxygen at sea level and 21% at 40,000 feet, why do I succumb to the effects of hypoxia within 20 seconds at that altitude?"
The answer is, ATMOSPHERIC PRESSURE! If you could picture all the gaseous nitrogen and oxygen molecules in the atmosphere, they would stack up from the surface of the earth to the fringe of space. All these molecules stacking on top each other create a great deal of weight, or pressure. At sea level, one square-inch of any surface has about 15 pounds of air sitting on top of it. At 18,000 feet, that same square inch has only 7.5 pounds per square-inch (psi) exerted on it. What has caused this atmospheric pressure drop? The answer is simple: There is more air stacked up at sea level than above 18,000 feet, and therefore, more weight.
As you recall, when molecules are subjected to this pressure, they are going to move closer together. This will make the air more dense with oxygen and nitrogen molecules. For example, if at sea level you take in a breath of air that has an atmospheric pressure of 15 psi, then that air may contain 500 billion molecules of oxygen (this a fictitious number to be used only as an example); if you go to 18,000 feet and take the same breath where atmospheric pressure is 7.5 psi, then you will pull in only 250 billion molecules of oxygen. But, you require 500 billion per breath to function normally, and you're getting only half of what you need. That's HYPOXIA!
Not only do gaseous molecules in the atmosphere expand with reduced total pressure, gases in the human body are also subject to the same expansion. There are several areas in the body- ears, sinuses, lungs, gastro-intestinal tract, and teeth - where these gases can expand and cause a variety of problems. As long as the gas can expand and escape, there will be no problem. But if the gas becomes trapped, then pain will be the usual result.
As we have discussed earlier, the air we breathe contains about 79% nitrogen. Nitrogen is inhaled into the lungs and distributed and stored throughout the body. According to gas laws, gases of higher pressure always exert force towards areas of low pressure. When you inhale nitrogen, it will be stored at a pressure of about 12 psi (79% nitrogen) of 15 psi (total atmospheric pressure), equal to about 12 psi).
When you ascend to altitude and the pressure around your body begins to drop, this creates a pressure gradient (higher nitrogen in the body than outside the body) and the nitrogen will try to equalize and escape outside the body. Sometimes this nitrogen can leave so quickly and in such quantify that it may form a bubble. If this bubble forms at a body joint, the pain it causes is know as "the bends."
These are just a few of the problems that can occur when the human body is exposed to high altitude conditions. These problems will always be there for aviation. But through education and knowledge of the mechanisms that cause these problems, we can take steps toward protection and prevention so that your BLUE SKIES won't give you a case of the blues.
by J.R. Brown
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Here to There: A History of Mapping
From the 16th to 18th centuries, many European mapmakers were convinced that California was an island — an Edenic paradise populated by black Amazons. The error persisted for over a hundred years after expeditions had proven that California was, in fact, firmly attached to the mainland. The idea of California as a fierce paradise appealed to Europeans, who were reluctant to let the mundane reality interfere with their vision of the world.
So in that spirit, we’re devoting this episode of BackStory to maps — asking what they show us about who we are and and where we want to go. How do maps shape the way we see our communities and our world? What do they tell us about the kind of information we value? And what do they distort, or ignore?
Please help us shape this show! Share your questions, ideas and stories below. Have opinions on New York vs. D.C. subway maps? On the merits or shortcomings of Google Maps? And do you even still use old-fashioned, ink-and-paper maps? Leave us a comment! | 3.386781 |
The Convention adjourned from July 26th to August 6th to allow the Committee of Detail – composed of John Rutledge of South Carolina, Edmund Randolph of Virginia, Nathaniel Gorham of Massachusetts, Oliver Ellsworth of Connecticut, and James Wilson of Pennsylvania – to prepare a rough draft of a constitution, based on the series of resolutions the delegates had debated, amended, and debated again. When the Convention re-convened, the Committee of Detail presented its report, made up of twenty-three articles. The Convention spent the remainder of August reviewing and further revising these articles.
We the People of…
Delegates quickly agreed to accept the Committee of Detail’s preamble and Articles I and II, affirming the new government would be called the Unites States of America and consist of Legislative, Executive, and Judicial branches. This agreement masked the critical issue that the Convention had debated throughout – was this to be a union of states or of people? The Committee of Detail’s constitution began, “We the people of the States (emphasis added) of New Hampshire, Massachusetts, Rhode-Island and Providence Plantations, Connecticut, New-York, New-Jersey, Pennsylvania, Delaware, Maryland, Virginia, North-Carolina, South-Carolina, and Georgia, do ordain, declare, and establish the following Constitution for the Government of Ourselves and our Posterity.” The Convention would not end with that language in the preamble.
Representation: Who, What, and How Many?
Discussion of the Committee of Detail report continued to include the structure and powers of the legislative branch. Some of the key questions included: Who can elect representatives? How many representatives will there be? What will be their qualifications?
Delegates debated whether to allow non-land owners to the right to vote for House members, or reserve the franchise to property owners. Gouverneur Morris wanted to restrict voting to those with property, considering them more educated and better able to choose wise leaders. “The ignorant and dependant,” Morris stated, “can be… little trusted with the public interest.” Colonel Mason countered arguments of this kind, saying all citizens should have equal voting rights and privileges. Doctor Franklin sided with Colonel Mason believing that restricting the right to vote to land owners would cause contention among the people. In the end Morris’s proposal to restrict the franchise to property owners was defeated soundly (7-1-1).
Just as the Convention rejected a plan to restrict voting to property owners, they also rejected a proposal to restrict elective office to property owners. South Carolina’s Charles Pinckney moved that “the President of the U.S., the Judges, and members of the Legislature should be required to swear that they were respectively possessed of a cleared unencumbered Estate” – in an amount to be agreed upon by members of the Convention. This proposal went nowhere. Benjamin Franklin expressed his “dislike of every thing that tended to debase the spirit of the common people,” and observed that “some of the greatest rogues he was ever acquainted with, were the richest rogues.” Madison reports that Pinckney’s motion “was rejected by so general a no, that the States were not called.”
The Convention did have a sentiment in favor of strong citizenship requirements for legislators. The Committee of Detail’s report required members of the House be U.S. citizens for three years prior to election, and members of the Senate for four years. Some, including George Mason and Morris, agreed that a lengthy citizenship requirement would protect the legislature from foreign intrigue. Others, including Madison and Franklin, pointed to the number of foreign friends who had helped the states during the war for independence. Delegates sided with Mason and Morris, agreeing to requirements that members of the House be citizens for seven years and members of the Senate for nine years prior to election.
On the question of how many representatives would make up the national legislature, Article IV of the Committee of Detail Report stated that the House of Representatives would initially consist of sixty-five members, and that in the future, members of the House would be added “at the rate of one for every forty thousand.” Madison, expecting the Union to grow rapidly, thought that rate would quickly lead the House to grow too large. Others thought that time would make this issue irrelevant. Mr. Nathaniel Gorham from Massachusetts asked, “Can it be supposed that this vast country including the Western territory will 150 years hence remain one nation? Mr. Oliver Ellsworth observed that “If the government should continue so long, alterations may be made in the Constitution” through the amendment process. Delegates agreed to add the language “not exceeding” to the one representative for 40,000 citizen ratio, making that a ceiling and not a floor. Controversy over this provision would re-emerge before the end of the Convention, however.
The Specter of Slavery
Likewise, controversy would emerge about slavery. Consideration of the apportionment of representatives raised the question of whether slaves would be included within that ratio. Morris rose on August 8 and gave a withering criticism of the institution. Moving to specify that this ratio would include only “free” inhabitants, Morris called slavery “a nefarious institution,” and “the curse of heaven”. Comparing free with slave states, Morris noted, on the one hand, “a rich and noble cultivation [which] marks the prosperity and happiness of the people,” and on the other “the misery and poverty which overspread the barren wastes of Virginia, Maryland, and the other states having slaves.” Morris’s motion was defeated 10-1, but the issue of how slavery would be addressed by the new union was by no means resolved.
For more detailed information on the Constitutional Convention, please visit Prof. Gordon Lloyd’s web companion to the Philadelphia Convention.
Posted in Countdown to the Constitution | 3.089209 |
With the development of science and technology, computer has become more and more popular in our daily life, which is intended to be a part of our life. But at the same time it also brings the safety problem, because increasing number of bad people would like to break into computer systems to steal the secret information. It seems that computer safety has been a serious problem by now. Maybe you could learn something about the safety terms in Microsoft so that you could adopt the different methods according to different cases.
What is malware? In fact malware, short for “malicious software”, is any kind of software which is installed without your complete permission and is not in need at all.The famous malware areviruses, worms, and Trojan horses, which are almost known to us all. Even though you are not familiar with them, you must have heard of it at ordinary times. If you want to protect your computer from the malware, you could make sure that the automatic updating is turned on all the time to get the latest updates.
2 antispyware software
Antispyware software helps protect your computer, and prevent the pop-ups, slow performance, and security threats caused by spyware and other adverse software. Every computer user must keep antispyware software up to date in order to keep in touch with the latest spyware. Aimed at protecting our computer, we could use Microsoft Security Essentials, free download software, to be against spyware and other malicious software.
A firewall is used to help screen out hackers, viruses, and worms that try to attack your computer through the Internet.In fact, if you are the one who use the computer at home, the most efficient and important step is to enable firewall when you start your computer. A virus will slip through and infect you; the only effective way by protecting yourself is using a firewall. A firewall monitors your Internet connections and allows you to specify which programs are allowed to connect and which are not.
4 antivirus software
Antivirus software is a kind of computer program which can be used to test, defend, and take actions to remove or delete malicious software program. As we all know, computer virus is some programs, which can specially disturb computer operation. So we should update antivirus software in regular time to prevent against the latest virus.
5 Windows password
Besides the above mentioned software, you could have an alternative at the same time, namely Windows password. With a password like this, you can prevent your privacy from being let out or being viewed. Of course you should set up a Windows password reset disk to set the password reset in case that you forget it.
As a computer user, you should have a general knowledge of these safety terms so that you can protect your computer better. And with these terms, your computer can be protected better than that without them. In a word, please have a brief understanding of them in the first place, and then you could know how important they are. | 3.1705 |
Just as there are many variants and forms of electronic malware and Internet-based threats around the globe, so there are many forms of protection against these threats. Signature-based detection is one of the multifarious forms of defense that have been developed in order to keep us safe from malicious content.
Although signature-based detection can be argued to have been overshadowed by more sophisticated methods of protection in some environments, it remains as a core ‘technique’ featuring in the anti-virus controls of packages and suites that work to protect a user’s system today.
How does signature-based detection work?
Signature-based detection works by scanning the contents of computer files and cross-referencing their contents with the “code signatures” belonging to known viruses. A library of known code signatures is updated and refreshed constantly by the anti-virus software vendor.
If a viral signature is detected, the software acts to protect the user’s system from damage. Suspected files are typically quarantined and/or encrypted in order to render them inoperable and useless.
Clearly there will always be new and emerging viruses with their own unique code signatures. So once again, the anti-virus software vendor works constantly to assess and assimilate new signature-based detection data as it becomes available, often in real time so that updates can be pushed out to users immediately and zero-day vulnerabilities can be avoided.
Next-generation signature-based detection
New variants of computer virus are of course developed every day and security companies now work to also protect users from malware that attempts to disguise itself from traditional signature-based detection. Virus authors have tried to avoid their malicious code being detected by writing “oligomorphic“, “polymorphic” and more recently “metamorphic” viruses with signatures that are either disguised or changed from those that might be held in a signature directory.
Despite these developments, the Internet at large does of course still function on a daily basis. Populated as it is by users who not only have up to date security software installed, but also by those who have educated themselves as to the type of risks discussed here. | 3.014808 |
By Jason Kohn, Contributing Columnist
Like many of us, scientific researchers tend to be creatures of habit. This includes research teams working for the National Oceanic and Atmospheric Administration (NOAA), the U.S. government agency charged with measuring the behavior of oceans, atmosphere, and weather.
Many of these climate scientists work with massive amounts of data – for example, the National Weather Service collecting up-to-the-minute temperature, humidity, and barometric readings from thousands of sites across the United States to help forecast weather. Research teams then rely on some the largest, most powerful high-performance computing (HPC) systems in the world to run models, forecasts, and other research computations.
Given the reliance on HPC resources, NOAA climate researchers have traditionally worked onsite at major supercomputing facilities, such as Oak Ridge National Laboratory in Tennessee, where access to supercomputers are just steps away. As researchers crate ever more sophisticated models of ocean and atmospheric behavior, however, the HPC requirements have become truly staggering.
Now, NOAA is using a super-high-speed network called “n-wave” to connect research sites across the United States with the computing resources they need. The network has been operating for several years, and today transports enough data to fill a 10-Gbps network to full capacity, all day, every day. NOAA is now upgrading this network to allow even more data traffic, with the goal of ultimately supporting 100-Gbps data rates.
“Our scientists were really used to having a computer in their basement,” says Jerry Janssen, manager, n-wave Network, NOAA, in a video about the project. “When that computer moved a couple thousand miles away, we had to give them a lot of assurances that, one, the data would actually move at the speed they needed it to move, but also that they could rely on it to be there. The amount of data that will be generated under this model will exceed 80-100 Terabits per day.”
The n-wave project means much more than just a massive new data pipe. It represents a fundamental shift in the way that scientists can conduct their research, allowing them to perform hugely demanding supercomputer runs of their data from dozens of remote locations. As a result, it gives NOAA climate scientists much more flexibility in where and how they work.
“For the first time, NOAA scientists and engineers in completely separate parts of the country, all the way to places like Alaska and Hawaii and Puerto Rico, will have the bandwidth they need, without restriction,” says Janssen. “NOAA will now be able to do things it never thought it could do before.”
In addition to providing fast, stable access to HPC resources, n-wave is also allowing NOAA climate scientists to share resources much more easily with scientists in the U.S. Department of Energy and other government agencies. Ideally, this level of collaboration and access to supercomputing resources will help climate scientists continue to develop more effective climate models, improve weather forecasts, and allow us to better understand our climate.
Powering Vital Climate Research
The high-speed nationwide HPC connectivity capability provided by n-wave is now enabling a broad range of NOAA basic science and research activities. Examples include:
- Basic data dissemination, allowing research teams to collect up-to-the-minute data on ocean, atmosphere, and weather from across the country, and make that data available to other research teams and agencies nationwide.
- Ensemble forecasting, where researchers run multiple HPC simulations using different initial conditions and modeling techniques, in order to refine their atmospheric forecasts and minimize errors.
- Severe weather modeling, where scientists draw on HPC simulations, real-time atmospheric data, and archived storm data to better understand and predict the behavior of storms.
- Advancing understanding of the environment to be able to better predict short-term and long-term environmental changes, mitigate threats, and provide the most accurate data to inform policy decisions.
All of this work is important, and will help advance our understanding of Earth’s climate. And it is all a testament to the amazing networking technologies and infrastructure that scientists now have at their disposal, which puts the most powerful supercomputing resources in the world at their fingertips – even when they are thousands of miles away. | 3.304265 |
The bacterium Micavibrio aeruginosavorus (yellow), leeching
on a Pseudomonas aeruginosa bacterium (purple).
What’s the news: If bacteria had blood, the predatory microbe Micavibrio aeruginosavorus would essentially be a vampire: it subsists by hunting down other bugs, attaching to them, and sucking their life out. For the first time, researchers have sequenced the genome of this strange microorganism, which was first identified decades ago in sewage water. The sequence will help better understand the unique bacterium, which has potential to be used as a “living antibiotic” due to its ability to attack drug-resistant biofilms and its apparent fondness for dining on pathogens.
Anatomy of a Vampire:
- The bacterium has an interesting multi-stage life history. During its migratory phase it sprouts a single flagellum and goes hunting for prey. Once it find a delectable morsel of bacterium, it attacks and irreversibly attaches to the surface, and sucks out all of the good stuff: carbohydrates, amino acids, proteins, DNA, etc.
- Sated, the cell divides in two via binary fission, and the now-depleted host is left for dead.
Hungry for Pathogens:
- M. aeruginosavorus cannot be grown by itself; it must be cultured along with another bacteria to feed upon. A 2006 study found that it only grew upon three bacterial species, all of which can cause pneumonia-like disease in humans. A more recent study showed that it can prey upon a wider variety of microbes, most of them potentially pathogenic, like E. coli.
- These studies also found that M. aeruginosavorus has a knack for disrupting biofilms, the dense collection of bacteria that cause harmful plaques on teeth and medical implants alike, and can be up to 1,000 more resistant to antibiotics than free-swimming bugs.
- The bacteria can also swim through viscous fluids like mucous and kills Pseudomonas aeruginosa, the bacterium that can colonize lungs of cystic fibrosis patients and form a glue-like film.
- These qualities have caught the eye of researchers who think it could be used as a living antibiotic to treat biofilms and various types of drug-resistant bacteria, which are a growing problem in medicine. Sequencing the organism’s genome is an important step in understanding its biochemistry and how it preys on other microbes.
Clues From the Vampire Code:
- The new study found that each phase of life involves the use (or expression) of different sets of genes. The migratory/hunting phase involves many segments that code for flagellum formation and genes involved in quorum sensing. The attachment phase involves a wide variety of secreted chemicals and enzymes that facilitate the flow of materials from the host.
- Micavibrio aeruginosavorus possesses no genes for amino acid transporters, a rather rare trait only seen in a few other bacterial species that depend heavily upon their host to help them shuttle these vital protein building-blocks. This absence helps explain the bacterium’s dependence on a narrow range of prey, from which it directly steals amino acids. Although it remains unclear exactly how the microbe attaches to and infiltrates other cells.
The Future Holds:
- The range of microbes upon which Micavibrio aeruginosavorus can survive is expanding; after being kept in laboratory conditions for years it has apparently evolved a more diverse diet. If this expansion continues, that could be a real problem for its use as an antibiotic; it could begin to eat beneficial gut bacteria, for example.
- Researchers claim it is harmless to friendly gut microbes, but it hasn’t been tested on all the varieties of bacteria present in humans.
- Several important steps must be taken before testing in people, like learning more about what traits makes another bacteria tasty to Micavibrio aeruginosavorus. Researchers speculate the bacterium may need to be genetically altered in order to go after specific pathogens, or to reduce the risk of it causing unforeseen complications.
Reference: Zhang Wang, Daniel E Kadouri, Martin Wu. Genomic insights into an obligate epibiotic bacterial predator: Micavibrio aeruginosavorus ARL-13. BMC Genomics, 2011; 12 (1): 453 DOI: 10.1186/1471-2164-12-453
Image credit: University of Virginia | 3.920127 |
Correctly identifying what is causing a problem is the most important step in pest control. We do our best here to help you do that. Sometimes we can identify the cause accurately enough from your phone or e-mail description of what is happening and what you see. Sometimes we can do this from photographs you submit, either electronically or printed on paper. But sometimes word descriptions and photographs aren't quite good enough, and we ask you to submit a specimen of an arthropod you have found, or the damage it has caused.
The information we give you is only as good as the information you give to us. I can't identify specimens that look like the one in the photograph above. Here are some hints that will help all of us:
1. Make sure any photographs are CLEAR and take several, from very close up to farther away. Make sure you have sufficient light, or that you compensate with your camera to make sure we can clearly see what you are trying to show us. Learn how to use the close up mode on your digital camera.
2. You have 20,000 of something flying around? Please give us at least - oh maybe - six of them. If it's something unusual, we need at least one full, intact set of key characteristics. If there are big individuals and little ones, try to submit a few of each size. Maybe they're different, maybe they're not, but we won't know for sure unless we see them.
3. Label your material. Where and when was it found? What does it seem to be doing?
4. You had 20,000 last week, but you can't find even one now? Maybe you don't have the problem anymore. Keep an eye on the situation and try not to worry.
5. That doesn't go for termites. If you think you had a termite swarm, worry! Keep a close eye on it, try to find a least one, even if it's only a wing, and submit it for identification.
6. You can kill most small pests by putting them in the freezer or by dropping them into alcohol. Any sort of alcohol will do. The alcohol not only kills them, it also preserves them. Never submit arthropod specimens in water (unless they are living aquatic animals). Moths and butterflies are easier to identify if they are not preserved in alcohol, so just freeze them and bring them in dry. We can also take live specimens.
7. Some insects and mites are most easily submitted on or in a piece of the plant they are living on. It's best if the sample is as fresh as possible. Don't bake it in a hot car.
8. A few creatures can't be identified from the sample you submit. Ants are most easily identified from the workers (the ones without the wings). Some spiders can only be identified to species if you have adults of both sexes. Small larvae, nymphs and eggs can be extremely difficult to identify. That's just the way it is.
9. Entomologists specialize. Sometimes we have to send things off. If they only have to go to the university, turn-around time can be quick. If they have to go further, it may be a long time before you hear back. This doesn't happen that often, though. | 3.213423 |
died Aug. 28, 1818, St. Charles, Mo., U.S.
black pioneer trader and founder of the settlement that later became the city of Chicago.
Du Sable, whose French father had moved to Haiti and married a black woman there, is believed to have been a freeborn. At some time in the 1770s he went to the Great Lakes area of North America, settling on the shore of Lake Michigan at the mouth of the Chicago River, with his Potawatomi wife, Kittihawa (Catherine). His loyalty to the French and the Americans led to his arrest in 1779 by the British, who took him to Fort Mackinac. From 1780 to 1783 or 1784 he managed for his captors a trading post called the Pinery on the St. Clair River in present-day Michigan, after which he returned to the site of Chicago. By 1790 Du Sable's establishment there had become an important link in the region's fur and grain trade.
In 1800 he sold out and moved to Missouri, where he continued as a farmer and trader until his death. But his 20-year residence on the shores of Lake Michigan had established his title as Father of Chicago. | 3.657313 |
Common Core Catholic Identity Initiative
A national working group has begun the Common Core Catholic Identity Initiative (CCCII) to develop and disseminate resources and guidelines to assist Catholic elementary and secondary schools in integrating elements of Catholic identity (Catholic values, Scripture, Church social teachings, encyclicals, etc.) into curriculum and instruction based on the Common Core State Standards.
The initial phase of CCCII focuses on K-8 English/Language Arts/ Literacy. Resources for other subjects and for 9-12 curriculum will be developed in later phases.
Forty-six states have agreed to adopt the Common Core State Standards, a set of high quality K-12 learning standards that includes rigorous content and application of knowledge using higher-order thinking skills, leading students to college and career readiness. Currently, Catholic schools are assessing what the implications of the standards and accompanying assessments may be for them.
While Catholic schools have their own local or diocesan standards, their ability to continue to provide high-quality education for their students is compelling them to consider adoption of the common core standards. Catholic schools will be impacted as curriculum resources and professional development opportunities become aligned with Common Core State Standards by producers of instructional materials, college teacher preparation programs, or regulations for participation in the federal programs that currently benefit their students and teachers. Within this environment, maintaining the uniqueness and integrity of the Catholic school will require integrating the demands of their mission and the academic expectations of their constituents and the wider education community.
To assist Catholic schools with enhancing Catholic identity integrated into the curriculum, the Common Core Catholic Identity Initiative (CCCII) has been launched as a collaborative project involving Catholic universities, corporations and sponsors invested in Catholic education, and the National Catholic Educational Association (NCEA).
The Common Core Catholic Identity Initiative has two goals:
- to empower Catholic schools and dioceses to design and direct the implementation of the Common Core standards within the culture and context of a Catholic school curriculum
- to infuse the Common Core standards with the faith/principles/values/social justice themes inherent in the mission and Catholic identity of the school.
The CCCII project aims to accomplish its goals by creating a process and a product:
Phase 1: Gather approximately 35 practitioners and curriculum and catechetics experts to pilot a CCCII ELA Unit development process to be shared with the larger Catholic educational community. (June 2012)
Phase 2: Revise and refine the unit development process so that it can be replicated in dioceses around the country.
Phase 3: Invite participation in development of additional CCCII ELA Units by Catholic educators around the country.
Phase 1: Utilize the expertise and strength of experienced and innovative teachers to develop complete units/exemplars that join Catholic identify with the Common Core curriculum standards. Utilize the expertise of CCCII leaders to develop supporting resources and guidelines. (June 2012)
Phase 2: Post exemplar units, guidelines, and resources developed in for the June 2012 launch for open access by Catholic educators on the Catholic School Standards Project Website www.catholicschoolsstandards.org) . (July 2012)
Phase 3: Expand exemplar units and Catholic Identity resources available for use by local Catholic schools.
Tailor the CCCII Unit development process for Catholic secondary schools.
Expand CCCII to include additional subject areas.
Meet the CCCII Leadership and Planning Teams | 3.366555 |
Instructors: Andrea Dykstra, Curt Van Dam, Kelli Ten Haken and Tami De Jong
1. Students will gain interest in the Unit on Alaska.
2. Students will be introduced to Alaska and the Iditarod race that takes place
in Alaska every year.
3. Students will be able to appreciate the beauty of Godís creation in Alaska.
4. Students will be able to see Godís majesty and power in their personal experiences.
In this lesson, the students will discuss what they know about Alaska. They will watch
a movie and then discuss how God shows His power and majesty through creation. Next,
they will be introduced to the Iditarod race by reading a story and then the teachers will
explain the game the students will play about the Iditarod through the unit. At the end of
class, students will have a chance to start work on their maps of Alaska and then the
teachers will end in closing prayer.
- Psalm 19:1-
The Heavens declare the glory of God; the skies proclaim the work of His hands.
- Other Scripture references that can be used through out the unit:
The Creation story in Gen. 1 and 2
Alaska: Spirit of the Wild
2. DVD player
5. Learning center and trade books
6. Example of the Iditarod Game
7. Book: Iditarod Dream by Ted Wood
8. Overhead projector, overhead and pen
9. Construction paper
10. Markers, crayons, colored pencils
1. On the first day of this unit, teachers should enter the room dressed in parkas,
snowshoes, scarves, mittens; anything that looks like what people in Alaska would
wear. Motion for the student to sit down. Once they are quiet, ask them where
they think the teachers are from and how they came to this conclusion. We would
expect conclusions such as the Artic, Antarctica, and possibly Alaska.
2. Have students take out a sheet of paper and write five things down that come to
their minds when they think of Alaska. Have them get into groups of three and
share what they wrote with their group. The students will be encouraged to share
the combined ideas from their group with the whole class. The teacher will write
down these ideas on the overhead.
3. Explain to the students that they are going to be learning about all of these of
these things and even more about Alaska in the upcoming unit.
4. Have each student write down one or two things about Alaska they would like
to know more about. Suggest ideas such as: What sports do they play in Alaska?
How many people live there? Is it really cold and snowy year round? Take these
ideas into consideration when planning the rest of the unit.
1. Put in the DVD Alaska: Sprit of the Wild. Students will watch the movie. It is forty
minutes long. Before they watch it, share with them the beauty that can be found in
Alaska. Tell them to look specifically for how they can see God in the things that are
shown on the film.
2. After the movie, discuss with the students what they thought of the movie. Ask them
questions such as what surprised you about this film? What did you learn about Alaska
that you didnít know before? What can we discover about God by watching this movie?
How can we get to know God better by studying Alaska?
3. Read Psalm 19:1 aloud. Read it again, this time have the students say it after you. Ask
them how this verse relates to Alaska. Hopefully they will make the connection that
creation shouts Godís praise. Alaska is so beautiful; this reflects on Godís majesty,
creativity and mercy. God loves us enough to give us beautiful creation simply so we
can enjoy it. We can see his fingerprints in Alaska.
4. Read Psalm 8 aloud. Again, ask them how this verse relates to Alaska. They will probably
have similar responses as above in step three. Share a personal experience of how he/
she has seen Godís power and majesty in His creation.
- For example, this is my own experience; you could share something similar to it:
One time I climbed the highpoint of Colorado with my dad. We started hiking
before the sun was up. As we were walking along the ridge of the mountain, the
sun began to rise; the colors were brilliant! We kept on hiking and hiking. I was
getting tired and hungry but soon we came close to the top. As I climbed up the
last little peak and the top of the mountain, I looked out and the view was
breathtaking!!! I had never seen so many snow capped mountains before. Sitting
up there on the mountaintop, I felt such a joy and peace. What a great God I
serve! He created all of this; His creation alone is enough to tell of His majesty.
5. Ask the students if any of them have had an experience like this; encourage them to
share if they would like.
6. Encourage them to find other verses that could relate to our study of Alaska and bring
them to class tomorrow to share.
1. Introduce the Iditarod race the studentís will be learning about by reading the book
Iditarod Dream by Ted Wood. As you are reading, stop periodically through out the
book and ask them to jot down a few of their thoughts. At the end of the book ask
them to share a few thoughts they wrote down about the book.
2. Introduce the game the students will be playing throughout the unit. Tell the students
they will be having their own Iditarod race in the classroom. Each student will make a
map of Alaska on construction paper. On this map, they will draw the trail of the
Iditarod race. They will have to map out the different checkpoints of the race on their
trails. It is their job to find out how many miles are between each checkpoint and how
many miles they can travel in one day.
3. Each day the students will move their markers on their maps how ever many miles we
decide as a class they can travel in one day. Every morning the students will receive
a ďracerís fateĒ card. These cards will say various things such as, ďyour dog has broken
a leg, move back twenty milesĒ, or ď you have found an extra bundle of food on the trail,
move ahead twelve milesĒ. The students will have to keep track of where they are on
the trail on their own maps and on a large map on the classroom bulletin board.
4. Each afternoon, students will have an opportunity to receive another card if they got
their homework done on time that day. This card could be good or bad, but the students
get to decide if they want to take it.
5. This activity will be incorporated into language arts. The students will be keeping a
race journal. As they play this game they can write their feelings about the race in the
journal as if they were an actual racer.
6. This game will also be incorporated into math. Students will need to do calculations to
play the game correctly. They will also discover how to find median, mean and
using the game.
1. The students will begin making their maps of Alaska for the Iditarod game. The
outline of the map of Alaska will be projected on the overhead so the students have
something to follow when they draw. Copies of the outline of this map will be available
for students to trace if they do not want to draw the map freehand.
2. The students can use crayons or colored pencils to make their maps on.
3. The trail outline and check points will be labeled on the overhead map, but the students
will need to research how many miles are in between each check point in a later class
1. Read Psalm 8 one more time and end in prayer, thanking God for His creativity that
is evident in all of creation, especially as it has been seen in Alaska today.
1. Students can do more research about the real Iditarod race on the Internet.
2. Students can read one of the many books about Alaska set up in the learning center.
3. Students can complete any activity set up in the learning center, including: math
story problems, language arts writing activities, and social studies and science
1. Observe how much students participate in the lesson. Have one teacher walk
around with a checklist and put checks by the names of the students who are
on task and participating by sharing, asking questions, diligently listening.
2. Observe how diligently students work on their maps. Check the next day to see
if they have completed them. Give them a check if they are finished and are done
Lesson Plans Unit Outline Home Page
Trade Books Learning Center | 3.683004 |
Tornadoes are the most intense storms on the planet, and they’re never discussed without at least some mention of the term wind shear. Many of us sitting at home, though, have no idea what wind shear is, or if we do, how it affects tornado production.
What is Wind Shear
Wind shear, although it might sound complex, is a simple concept. Wind shear is merely the change in wind with height, in terms of wind direction and speed. I think that we all understand that the wind is generally stronger in the atmosphere over our heads than it is here on the ground, and if we think of the atmosphere in terms of the three dimensions that it has, it should not be surprising that the wind above us might also be blowing from a different direction than the wind at the ground. When that happens–the wind speed and direction vary with height–wind shear is occurring.
Wind Shear and Supercell Thunderstorms
This wind shear is an important part of the process in the development of a supercell thunderstorm, from which the vast majority of strong tornadoes form.
All thunderstorms are produced by a powerful updraft–a surge of air that rises from the ground into the upper levels of the atmosphere, and when this updraft forms in an area where wind shear is present, the updraft is influence by this speed and different direction of the wind above, pushing the column of air in the updraft into a more vertical alignment.
Rain’s Influence on Tornado Production
Needless to say, thunderstorms typically produce very heavy rain, and rain-cooled air is much heavier than the warm air of the updraft, so the rain-cooled air, produces a compensating downdraft (what comes up, must come down). This downdraft pushes the part of the rotating air that was forced in its direction by the stronger wind aloft downward, and the result is a horizontal column of rotating air.
That’s Not a Tornado!
I know what you’re thinking that you’ve seen enough TLC or Discovery Channel shows to know that a horizontal column of air is NOT a tornado; you need a vertical column of air.
This Can Be a Tornado
You’re right, but remember the updraft that is driving the thunderstorm is still working, and it’s able to pull the horizontal, spinning column of air into the thunderstorm, resulting in a vertical column of spinning air.
(NOAA image showing vertical column of air in a supercell thunderstorm)
The result is a rotating thunderstorm capable of producing a tornado, and it would not be possible without wind shear.
(NOAA image showing tornado formation in supercell thunderstorm) | 4.149361 |
Reversal of fortune
To unlock the vast, untapped potential of the world’s drylands, we must learn from the people who live in them, says Dr Jonathan Davies.
Drylands are a major global biome, home to a great diversity of species and some of our most treasured natural heritage. They are also home to over 2 billion people and in the developing world in particular they are associated with poverty and social inequity. Global development and environment goals are not being met in the drylands: by 2015 many dryland regions are set to fail to achieve the Millennium Development Goals, whilst progress towards the goals and objectives of the UN environmental conventions (the Convention to Combat Desertification and the Convention on Biological Diversity in particular) is generally poor.
Recent experiences in the drylands of emerging countries, such as China and India, illustrate that economic development in drylands can outpace that in areas that are usually considered “high potential”. Although development is often associated with degradation, experiences in Sub Saharan Africa illustrate that economic development can be greatly enhanced through protection of biodiversity as a source of income. By taking an even broader, global view of drylands and examining industrialised dryland countries, it becomes clear that for every seemingly-insurmountable challenge we are able to find evidence of a viable solution somewhere in the world.
To address the challenges of the drylands, we need to understand their unique features and how these have to be managed. Perhaps the most important of these is climate unpredictability: the amount of precipitation varies enormously between areas, between seasons and between years. The sheer magnitude of this uncertainty is hard to grasp, but in many drylands the normal range of rainfall, drought-years aside, can be plus or minus 50% of the average. Yet development in many water-deficit areas continues to favour agricultural practices that expose farmers to huge risks whilst simultaneously degrading the natural resource base on which they depend.
Climate change is a cause for concern in dryland areas, but also an opportunity for new approaches and new learning that illustrate the value of dryland areas. Dryland ecosystems and people are highly adaptable and can survive in their uncertain climate.. Whether drylands become wetter or drier as a result of climate change, they will almost invariably become more unpredictable and their adaptive capacity will be vital to their future. Drylands more than any other ecosystem have the capacity to deal with that unpredictability and we have a great deal to learn from them.
Contrary to popular perception, drylands are not necessarily poverty traps. Dryland ecosystems and their goods and services already contribute significantly to national and international economies. The vibrant tourism sector in Eastern and Southern Africa relies heavily on the biodiversity of drylands. Globally-important dryland commodities include grain, meat and milk and dryland goods like Gum Arabic, Henna, Aloe, and Frankincense. Recent years have seen the commercial development of natural medicines from drylands, and untold numbers of medicinal plants remain un-researched, known only to the dryland inhabitants who have used and conserved them for centuries.
Local knowledge of the drylands is rich and is a powerful resource to be harnessed. There has been a tendency to dismiss this knowledge, because local dryland practices have been portrayed as backward or inappropriate and in need of replacing. The current emergency in the Horn of Africa graphically illustrates the outcome of this attitude: populations are exposed to insupportable risk as a result of losing their traditional strategies and being pushed into new ways of life that simply don’t work. Where people are driven towards catastrophe it is almost guaranteed that the environment will face similar consequences. Customs and cultures that are intimately connected to biodiversity become contorted into a system of pure survival where respect for the environment becomes an unaffordable luxury.
The scientific explanation of the rationale behind traditional strategies has been known for long enough to develop innovative new approaches to sustainable drylands management. Development support has to enable management of the extreme climatic uncertainty of drylands and needs to be built on understanding of the drivers of continuous change in dryland ecosystems. These are dynamic ecosystems in which adaptation and flexibility are pre-requisites for survival. We need to learn from past failures and successes and ensure that development and humanitarian interventions recognize dryland characteristics and build on local knowledge and capacity to turn the existing opportunities into equitable and sustainable wealth creation. In particular we need to generate greater awareness of the tremendous opportunities for strengthening biodiversity-based livelihoods to diversify dryland economies and strengthen resilience.
IUCN’s vision 2020 emphasizes the need to strengthen the Union’s work on conserving the diversity of life while also connecting nature conservation to wider societal objectives such as security and poverty reduction. This vision cannot be reached if we fail to understand and address the unique challenges of the drylands. IUCN, with its great diversity of members and commission members, has a vital role to play in securing effective global action to address dryland issues and in enabling dryland communities to develop their nature-based solutions to risk management and sustainable development.
Dr Jonathan Davies is Coordinator of IUCN’s Global Drylands Initiative. | 3.258151 |
Is this bone a Neanderthal flute?
Cave Bear femur fragment from Slovenia, 43+kya
DOUBTS AIRED OVER NEANDERTHAL BONE 'FLUTE'
(AND REPLY BY MUSICOLOGIST BOB FINK)
Science News 153 (April 4, 1998): 215.
By B. Bower
Amid much media fanfare, a research team in 1996 trumpeted an ancient, hollowed out bear bone pierced on one side with four complete or partial holes as the earliest known musical instrument. The perforated bone, found in an Eastern European cave, represents a flute made and played by Neandertals at least 43,000 ye us ago, the scientists contended.
Now it's time to stop the music, say two archaeologists who examined the purported flute last spring. On closer inspection, the bone appears to have been punctured and gnawed by the teeth of an animal -- perhaps a wolf -- as it stripped the limb of meat and marrow report, April Nowell and Philip G. Chase, both of the University of Pennsylvania in Philadelphia. "The bone was heavily chewed by one or more carnivores, creating holes that became more rounded due to natural processes after burial," Nowell says. "It provides very weak evidence for the origins of [Stone Age] music." Nowell presented the new analysis at the annual meeting of the Paleoanthropology Society in Seattle last week.
Nowell and Chase examined the bone with the permission of its discoverer, Ivan Turk of the Slovenian Academy of Sciences in Ljubljana (S.N.: 11/23/96, p. 328). Turk knows of their conclusion but still views the specimen as a flute.
Both open ends of the thighbone contain clear signs of gnawing by carnivores, Nowell asserts. Wolves and other animals typically bite off nutrient-rich tissue at the ends of limb bones and extract available marrow. If Neandertals had hollowed out the bone and fashioned holes in it, animals would not have bothered to gnaw it, she says.
Complete and partial holes on the bone's shaft were also made by carnivores, says Nowell. Carnivores typically break open bones with their scissor like cheek teeth. Uneven bone thickness and signs of wear along the borders of the holes, products of extended burial in the soil, indicate that openings made by cheek teeth were at first less rounded and slightly smaller, the researchers hold.
Moreover, the simultaneous pressure of an upper and lower tooth produced a set of opposing holes, one partial and one complete, they maintain.
Prehistoric, carnivore-chewed bear bones in two Spanish caves display circular punctures aligned in much the same way as those on the Slovenian find. In the March Antiquity, Francesco d'Errico of the Institute of Quaternary Prehistory and Geology in Talence, France, and his colleagues describe the Spanish bones.
In a different twist, Bob Fink, an independent musicologist in Canada, has reported
on the Internet
(http://www.webster.sk.ca/greenwich/fl-compl.htm) that the spacing of the two complete and two partial holes on the back of the Slovenian bone conforms to musical notes on the diatonic (do, re, mi. . .) scale.
The bone is too short to incorporate the diatonic scale's seven notes, counter Nowell and Chase. Working with Pennsylvania musicologist Robert Judd, they estimate that the find's 5.7-inch length is less than half that needed to cover the diatonic spectrum. The recent meeting presentation is "a most convincing analysis," comments J. Desmond Clark of the University of California, Berkeley, although it's possible that Neandertals blew single notes through carnivore-chewed holes in the bone.
"We can't exclude that possibility," Nowell responds. "But it's a big leap of faith to conclude that this was an intentionally constructed flute."
TO THE EDITOR, SCIENCE NEWS (REPLY BY BOB FINK, May 1998)
(See an update of this discussion on Bob Fink's web site, November 2000)
The doubts raised by Nowell and Chase (April 4th, DOUBTS AIRED OVER NEANDERTHAL BONE 'FLUTE') saying the Neanderthal Bone is not a flute have these weaknesses:
The alignment of the holes -- all in a row, and all of equivalent diameter, appear to be contrary to most teeth marks, unless some holes were made independently by several animals. The latter case boggles the odds for the holes ending up being in line. It also would be strange that animals homed in on this one bone in a cave full of bones, where no reports of similarly chewed bones have been made.
This claim is harder to believe when it is calculated that chances for holes to
be arranged, by chance, in a pattern that matches the spacings of 4 notes of a
diatonic flute, are only one in hundreds to occur .
The analysis I made on the Internet (http://www.webster.sk.ca/greenwich/fl-compl.htm) regarding the bone being capable of matching 4 notes of the do, re, mi (diatonic) scale included the possibility that the bone was extended with another bone "mouthpiece" sufficiently long to make the notes sound fairly in tune. While Nowell says "it's a big leap of faith to conclude that this was an intentionally constructed flute," it's a bigger leap of faith to accept the immense coincidence that animals blindly created a hole-spacing pattern with holes all in line (in what clearly looks like so many other known bone flutes which are made to play notes in a step-wise scale) and blindly create a pattern that also could play a known acoustic scale if the bone was extended. That's too much coincidence for me to accept. It is more likely that it is an intentionally made flute, although admittedly with only the barest of clues regarding its original condition.
The 5.7 inch figure your article quoted appears erroneous, as the centimeter scale provided by its discoverer, Ivan Turk, indicates the artifact is about 4.3 inches long. However, the unbroken femur would originally have been about 8.5 inches, and the possibility of an additional hole or two exists, to complete a full scale, perhaps aided by the possible thumbhole. However, the full diatonic spectrum is not required as indicated by Nowell and Chase: It could also have been a simpler (but still diatonic) 4 or 5 note scale. Such short-scale flutes are plentiful in homo sapiens history.
Finally, a worn-out or broken flute bone can serve as a scoop for manipulation of food, explaining why animals might chew on its ends later. It is also well-known that dogs chase and maul even sticks, despite their non-nutritional nature. What appears "weak" is not the case for a flute, but the case against it by Nowell and Chase.
Letter to the Editor: Antiquity Journal:
"A Bone to Pick"
By Bob Fink
I have a bone to pick with Francesco d'Errico's viewpoint in the March issue of Antiquity (article too long to reproduce here) regarding the Neanderthal flute found in Slovenia by Ivan Turk. D'Errico argues the bone artifact is not a flute.
D'Errico omits dealing with the best evidence that this bone find is a flute.
Regarding the most important evidence, that of the holes being lined up, neither d'Errico nor Turk make mention of this.
This line-up is remarkable especially if they were made by more than one carnivore, which apparently they'd have to be, based on Turk's analysis of the center-spans of the holes precluding their being made by a single carnivore or bite (Turk,* pp.171-175). To account for this possible difficulty, some doubters do mention "one or more" carnivores (Chase & Nowell, Science News 4/4/98).
My arguments over the past year pointed out the mathematical odds of the lining up of the holes occurring by chance-chewing are too difficult to believe.
The Appendix in my essay ("Neanderthal Flute --A Musicological Analysis") proves that the number of ways a set of 4 random holes could be differently spaced (to produce an audibly different set of tones) are 680 ways. The chances a random set would match the existing fragment's spacing [which also could produce a match to four diatonic notes of the scale] are therefore only one in hundreds. If, in calculating the odds, you also allowed the holes to be out of line, or to be less than 4 holes as well, then the chance of a line-up match is only one from many tens of thousands.
And yet randomness and animal bites still are acceptable to account for holes being in line that could also play some notes of the scale? This is too much coincidence for me to believe occurred by chance.
D'Errico mentions my essay in his article and what he thought it was about, but he overstates my case into being a less believable one. My case simply was that if the bone was long enough (or a shorter bone extended by a mouthpiece insert) then the 4 holes would be consistent and in tune with the sounds of Do, Re, Mi, Fa (or flat Mi, Fa, Sol, and flat La in a minor scale).
In the 5 points I list below, extracted from Turk's monograph in support of this being a flute, d'Errico omits dealing with much of the first, and all of the second, fourth and sixth points.
Turk & Co's monograph shows the presence on site of boring tools, and includes experiments made by Turk's colleague Guiliano Bastiani who successfully produced similar holes in fresh bone using tools of the type found at the site (pp. 176-78 Turk).
They also wrote (pp. 171-75) that:
1. The center-to-center distances of the holes in the artifact are smaller than that of the tooth spans of most carnivores. The smallest tooth spans they found were 45mm, and the holes on the bone are 35mm (or less) apart;
2. Holes bitten are usually at the ends of bones rather than in the center of them;
3. There is an absence of dents, scratches and other signs of gnawing and counter-bites on the artifact;
4. The center-to-center distances do not correspond to the spans of carnivores which could pierce the bone;
5. The diameters of the holes are greater than that producible by a wolf exerting the greatest jaw pressure it had available -- it's doubtful that a wolf's jaws would be strong enough (like a hyena's) to have made the holes, especially in the thickest part of the wall of the artifact.
6. If you accept one or more carnivores, then why did they over-target one bone, when there were so many other bones in the cave site? Only about 4.5% of the juvenile bones were chewed or had holes, according to Turk (p. 117).
* Turk, Ivan (ed.) (1997). Mousterian Bone Flute. Znanstvenoraziskovalni
Center Sazu, Ljubljana, Slovenia.
Maintained by Francis F. Steen, Communication Studies, University of California Los Angeles | 3.708007 |
My passion is studying early man, specifically how we became who we are. Is our violence an aberration or part and parcel of survival? No other mammal kills their own, but maybe–as the alpha on the planet–our greatest threat to our survival is our own species, so we’re forced to destroy each other.
What was lacking in H. Habilis that led to their extinction, to be replaced by the big-brained, scrawny Homo erectus? Habilis was preyed upon by species with bigger claws, sharper teeth and thicker skin. Habilis (and my friend Lyta) scavenged their left-overs, in between hiding from the imposing mammals that dominated the Plio-Pleistocene African savanna. But, eventually hiding wasn’t enough and H. erectus took over (we don’t know if they fought with each other or if habilis left ‘with a whimper’).
H. erectus, with his longer lower limbs for running and walking efficiency, his bigger brain especially in the areas for planning and forethought (and speech depending upon whose research you’re reading) was tall, thin, and barrel-chested, hardly daunting in a world of sabertooth cats, mammoth and giant sloths. Yet , it is he who spread from Africa to China, India, the Middle East, Java. It is he–not predator cats or alligators–who developed a highly adaptable culture allowing him to survive a wide range of climates and habitats.
That is the first of their firsts. Want more?
- first appearance of systematic hunting.
- first use of fire (though arguably no control of it)
- first indication of extended childhood (thanks to the helplessness of their infants)
- first indication of the ability to lead a more complex life (their Acheulian tools were sophisticated, their hunting was planned)
- first to wear clothing (how else to survive Georgia and China)
- first to create complex tools and weapons
Their faces were short but wide and the nose projected forward, hinting at the typical human external nose. They had a pronounced brow ridge. Their cranium was long and low and somewhat flattened at the front and back. The cranial bone was thicker than earlier hominids. Remnants show damage from being hit in the head by something like clubs or heavy rocks. Their arms and legs were also robust, with thicker bones and clear evidence of being heavily muscled. The suspicion is they were a more violent species than habilis. Is that why habilis disappeared? The tougher group survived and bred offspring with their thicker, more protective skulls.
You probably remember my friend Lyta is a Homo habilis (see her page). I’ve lived her life through Otto‘s ability to ‘see’ into the past. Where other primates rest when they have enough to eat, she thinks and shares information with her band. Where most mammals sleep when they aren’t hunting, playing or resting, Lyta worked–knapped tools, collected food for a cache, planned. I have come to believe that her survival depended not so much on her physique (which was sorely lacking in that physical time) as what was inside of her: her courage, ability to plan ahead, strength of her convictions, what we call ‘morals’. These are very human traits that can’t be preserved in bones and teeth. I wouldn’t know they existed if not for Otto. I’ve posted an excerpt from that research on Scribd.com (Born in a Treacherous Time).
My next project is to determine how man migrated throughout the world. Where did he get the courage? Was he forced out because he couldn’t defend his territory? Or was it wanderlust? Was he a seeker, wanting more for his life? Did he get bored and need to challenge his constantly-growing brain? | 3.038001 |
Xantusiidae is a clade of viviparous (live bearing) lizards that ranges from southwestern North America and Baja California (Xantusia) into Central America (Lepidophyma) and Cuba (Cricosaura). Xantusia magdalena occurs in Baja California. Xantusiidae is a relatively small clade, with 3 genera and approximately 30 living species. Lepidophyma is the most speciose (~17 species), whereas Cricosaura is monotypic. Xantusiids have a reasonably good fossil record extending from the mid-Paleocene onward in western North America.
Xantusiids are fascinating lizards for several reasons. First, although they are almost uniformly diminuitive (Xantusia magdalena measures less than 4 cm snout-vent length, and the largest xantusiid species measure about 10 cm snout-vent length), xantusiids generally take several years to reach sexual maturity, and several species give birth to just 1 or 2 offspring. It is a more usual reproductive strategy for small lizards to mature quickly and produce large numbers of offspring, to increase their chances of survival. Despite this low reproductive potential, xantusiid neonates actually have a high life expectancy; this can be attributed at least in part to their secretive lifestyle, which leads to the second reason why xantusiids are particularly interesting -- microhabitat specialization.
Microhabitat specialization is an ecological hallmark of Xantusiidae. Many populations are narrowly restricted to specific niches -- crevices (e.g., Xantusia henshawi in exfoliating granitic cap rocks), interstices in agaves and yuccas in dry climates (e.g., X. magdalena), decaying logs in wet climates (e.g., Lepidophyma flavimaculatum) -- and individuals may be found under the same patch of cover throughout their lives!
These microhabitat restrictions result in extremely disjunct geographical distributions, and also may be responsible for some morphological convergence within the group (e.g., flattened skulls for crevice dwelling). Xantusiidae also includes two insular endemics: the Cuban Cricosaura typica is the only xantusiid found in the West Indies and is interpreted as one of the Caribbean's few ancient endemic vertebrate lineages; and Xantusia riversiana (formerly Klauberina riversiana) is limited to three of the Channel Islands off the coast of California.
The phylogenetic relationships of Xantusiidae are problematic. Morphology and molecules produce different topologies within the clade: morphology recovers a Cricosaura + Lepidophyma clade, while mitochondrial genes recover a Lepidophyma + Xantusia clade. Lack of resolution of relationships within Xantusiidae has hindered the placement of this clade within the squamate tree. Xantusiidae is a "tree-changing" taxon: it causes homoplasy wherever it is placed, and its placement can tip the balance between the two primary competing hypotheses of scleroglossan relationships. Xantusiidae is traditionally placed within Scincomorpha, but some analyses have placed it near Gekkota. Thus, Xantusiidae is either a highly derived, or extremely basal, scleroglossan clade. Previous analyses of squamate phylogeny have almost certainly suffered in relying on species of the readily available -- but relatively derived -- genus Xantusia as exemplars for Xantusiidae. Cricosaura or a species of Lepidophyma would be more appropriate, but both are exceedingly rare in collections; indeed, some species of Lepidophyma are known from only 1 or 2 specimens.
Whatever the placement of Xantusiidae within squamates, there is no doubt that xantusiids are monophyletic. The following are some of the hypothesized synapomorphies of the lineage (from Estes et al., 1988), most of which can be seen in the skull reconstructions above: supratemporal fenestra closed primarily by postorbital; parietals paired well into postembryonic ontogeny; parietal table extensive posteriorly, largely obscuring braincase in dorsal view, supratemporal process short; vomers fused; ectopterygoid contacts palatine anterolaterally, excluding maxilla from suborbital fenestra; ectopterygoid enlarged medially, restricting suborbital fenestra.
About the Species
This specimen was collected in Baja California Sur, Mexico. It was made available to the University of Texas High-Resolution X-ray CT Facility for scanning by Dr. Jessie Maisano of The University of Texas and Dr. Jacques Gauthier of Yale University. Funding for scanning was provided by an NSF grant (DEB-0132227) to Dr. Jack Sites of Brigham Young University. Funding for image processing was provided by a National Science Foundation Digital Libraries Initiative grant to Dr. Timothy Rowe of The University of Texas at Austin.
About this Specimen
The specimen was scanned by Matthew Colbert on 18 May 2005 along the coronal axis for a total of 615 1024x1024 pixel slices. Each slice is 0.0152 mm thick, with an interslice spacing of 0.0152 mm and a field of reconstruction of 7 mm.
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. Proceedings of the California Academy of Sciences (Series 2) 5:523-534.
Zweifel, R. G., and C. H. Lowe. 1966. The ecology of a population of Xantusia vigilis
, the desert night lizard. American Museum Novitates 2247:1-57.
Xantusiidae page on the EMBL Reptile Database
Three-dimensional volumetric renderings of the skull with the scleral ossicles, hyoid and jaw removed, and of the isolated left mandible. All are 2mb or less. | 3.436857 |
Creator: Gust, Iris
Description: The brochure promotes urban transportation policy to increase the use of renewable energy to 100%. Seen globally, transport is one of the main sources of greenhouse gas emissions. Yet fossil fuels are becoming scarce, will become increasingly expensive and will eventually stop being viable as transport fuels. Before this happens, climate change will have begun to have a serious impact on human lives. The authors believe that it is crucial to replace fossil fuels with renewable energy as soon as possible, especially in the transport sector. Making urban transport independent of fossil fuel is a great challenge, but the authors cite growing evidence that it can be achieved.
Contributing Partner: UNT Libraries | 3.333023 |
In some people, macular degeneration advances so slowly that it has little effect on their vision. But in others, the disease progresses faster and may lead to vision loss. Sometimes only one eye is affected, while the other eye remains free of problems for many years. People with dry macular degeneration in one eye often do not notice any changes in their vision. With one eye seeing clearly, they can still drive, read, and see fine details. Some people may notice changes in their vision only if macular degeneration affects both of their eyes. Both dry and wet macular degeneration cause no pain.
Symptoms of macular degeneration include:
Blurred vision —This is an early sign. An example of early findings is that you may need more light for reading and other tasks.
Difficulty seeing details in front of you —You may have a difficult time seeing words in a book or faces.
Blind spot —A small, growing blind spot will appear in the middle of your field of vision. This spot occurs because a group of cells in the macula have stopped working properly. Over time, the blurred spot may get bigger and darker, taking more of your central vision.
Crooked lines —An early symptom of wet macular degeneration is straight lines that will appear crooked or wavy. This happens because the newly formed blood vessels leak fluid under the macula. The fluid raises the macula from its normal place at the back of the eye and distorts your vision.
Lighting —Images appear more gray in color and colors are not as bright
Contact your ophthalmologist immediately for an eye exam if you notice:
- Visual distortions
- Sudden decrease in central vision
- A central blind spot
- Any other visual problems
- Reviewer: Christopher Cheyer, MD
- Update Date: 09/01/2011 - | 3.314843 |
Although uncommon, an entirely different group of factors plays a role when an athlete suffers a stroke.
Head and neck trauma are often factors in stroke during athletic competitions. Direct head trauma can result in leakage from blood vessels, depriving large regions of the brain of necessary nutrients.
Violent forward and backward movement of the head can result in tearing the inner lining of vital arteries responsible for directing blood to the brain. This condition, known as arterial dissection, can form a clot within the affected blood vessel or become a source of small clots. These smaller clots often move toward the brain as emboli and block other arteries.
Treatment for arterial dissection involves the use of blood thinning medications and avoiding violent collision sports.
Another common risk factor for stroke in athletes is the existence of a patent foramen ovale (PFO). A PFO is a hole between the upper chambers of the heart, the right and left atria. The foramen ovale forms in the fourth week of embryonic development and should close in the first three months after birth. When it does not close, it is considered patent or open.
This abnormal channel allows direct passage of blood clots to the brain. These clots often originate in the legs and may result from immobilized lower extremities.
PFOs can be treated with equal success by surgical closure or blood thinning medications. Athletes appear to do better with surgical closure and usually make a full recovery to return to sports.
While considered rare, strokes do occur in athletes and treatment requires a different approach. | 3.445416 |
A 2012 survey conducted by the Association for Pet Obesity Prevention found 52.5 percent of dogs and 58.3 percent of cats to be overweight or obese by their veterinarian. This translates to nearly 80 million dogs and cats in America with a weight problem. Dr. George Banta, chair of the Veterinary Technology department at Brown Mackie College - Akron and Dr. Mary Jo Wagner, attending veterinarian at Argosy University, Twin Cities, offer useful information for pet owners.
How can you tell if your pet is overweight? “It’s not the number of pounds, it’s how the animal carries the weight,” says Banta. “The number on the Body Condition Score is more important than pounds.” The Body Condition Score offers a way to assess the condition of an animal, usually on a scale from one to five, taking into account height, weight, and relative proportions of muscle and fat.
With a little knowledge, you can use sight and touch to figure your pet’s general condition. “When looking down on a dog or cat from above,” says Banta, “the body should slim to a discernable waist. An animal is too thin if you can see the spine or ribs; however, you should be able to feel them beneath the fur.” An animal of ideal weight will also display a pelvic tuck when viewed from the side.
“Just like humans, when animals overeat, they face increased risk for health problems like diabetes, heart disease, gastrointestinal problems and cancer,” continues Banta. In fact, these risks also include a shortened life expectancy.
Many owners feed pets according to the manufacturer’s suggested amounts; however, this instruction may not be right for your pet. “These guidelines are meant to cover all animals of a certain weight range,” says Wagner. “An owner must consider the age and activity level of each pet. The more active they are, the more calories they will burn in a day.”
Metabolism rates vary in animals the same way they do in people. Metabolism is the body process in which food is broken down for energy; another factor that affects the amount of food a pet needs. Wagner advises owners to keep an eye on body condition to judge whether a pet is eating properly. “If your pet shows signs of being overweight, simply cut back the amount of food given at each meal. Then weigh the pet in two or three weeks to see if it has made a difference,” she says.
Choosing the right food for your pet is important as well. Different brands of pet food contain varying amounts of protein, fat, carbohydrates and calories. “As a general rule, young, active dogs need high protein food,” says Wagner. “Older dogs need higher fiber to keep the gastrointestinal (GI) tract moving.” Ingredients listed on the package appear in descending order of volume; the first item on the list is most abundant in the food.
Most of us love to give treats, but many of us don’t realize how many we offer each day. “A 40-pound dog is one quarter the size of a 160-pound person,” Wagner says. “They have smaller stomachs. Look at calories in everything your pet eats. After that, it’s simple math.”
“Table scraps are a definite no. Zip, zilch, nada,” says Banta. “They are not good for two reasons. First, foods like chocolate, caffeine, grapes and raisins can be toxic to dogs. Second, the high fat content associated with table scraps, especially holiday trimmings, can lead to the onset of acute pancreatitis, which can be fatal.”
He recommends offering a kibble of food or a carrot instead of a cookie. If you must give cookies, try breaking them in half. “Pets do enjoy treats as a reward; however, attention from you is also a reward. It’s important to praise animals. In some ways, spending time with them is better than a treat,” Wagner says. | 3.283053 |
On this day in 1951, more than six years after the end of World War II in Europe, President Harry S. Truman signed a proclamation officially ending U.S. hostilities with Germany.
The official end to the war came nine years, 10 months and 13 days after Congress had declared war on Nazi Germany. The lawmakers had responded to a declaration of war issued by the Third Reich in the aftermath of the Dec. 7, 1941, Japanese attack on Pearl Harbor and other U.S. bases in the Pacific.
The president explained why he had waited so long after the fighting had ended to act: It had always been America’s hope, Truman wrote, to create a treaty of peace with the government of a united and free Germany, but the postwar policies pursued by the Soviet Union “made it impossible.”
After the war, the United States, Britain, France and the Soviet Union divided Germany into four zones of occupation. Berlin, while located wholly within the Soviet zone, was jointly occupied by the wartime allies and also subdivided into four sectors because of its symbolic importance as the nation’s historic capital and seat of the former Nazi government.
The three western zones were merged to form the Federal Republic of Germany in May 1949, and the Soviets followed suit in October 1949 with the establishment of the German Democratic Republic.
The East German regime began to falter in May 1989, when the removal of Hungary’s border fences punched a hole in the Iron Curtain, allowing tens of thousands of East Germans to flee to the West. Despite the grants of general sovereignty to both German states in 1955, neither of the two German governments held unrestricted sovereignty under international law until after they were reunified in October 1990. | 4.351849 |
Fewer rare sea turtles will die on the swordfish industry's longlines in Hawaii under an agreement between environmental groups and the government. The agreement settles a lawsuit challenging the federal government's plans that would have dramatically increase the number of turtles that could be killed. The Turtle Island Restoration Network, Center for Biological Diversity and KAHEA sued the National Marine Fisheries Service for allowing 46 imperiled Pacific loggerhead turtles to be hooked last year. The new court-ordered settlement caps the number at 17 per year. Meanwhile the National Marine Fisheries Service is weighing whether loggerheads need more protection under the Endangered Species Act.
"It made absolutely no sense to have one arm of the National Marine Fisheries Service increasing the lethal capture of loggerheads, while the other arm is in the process of determining whether loggerheads should be uplisted from threatened to endangered," said Todd Steiner, biologist and executive director of Turtle Island Restoration Network. "With extinction looming, these animals need more protection, not less."
"With this decision, Hawaii's public-trust ocean resources can be better managed for our collective best interest, and not just the interests of this commercial fishery," said KAHEA program director Marti Townsend. "This is a victory not just for the turtles, but for Hawaii's people who rely on a healthy, functioning ocean ecosystem."
Conservation groups represented by Earthjustice filed a federal lawsuit challenging a 2009 rule allowing the swordfish fleet to catch nearly three times as many loggerhead sea turtles as previously permitted. This settlement freezes the number at the previous cap of 17 while the government conducts additional environmental studies and decides whether or not to classify the loggerhead as endangered, rather than its current, less-protective status of threatened. For leatherback turtles, the bycatch limit remains at 16 per year. In 2010, eight Pacific leatherbacks and seven loggerheads were caught in the longline fishery, according to the National Marine Fisheries Service. There have already been 4 loggerheads captured in 2011, which has sea turtle conservationists concerned.
"Sea turtles have been swimming the oceans since the time of dinosaurs. But without a change in management, they won't survive our voracious quest for swordfish and tuna," said Miyoko Sakashita, oceans director at the Center for Biological Diversity. "If loggerheads are going to survive in the North Pacific, we need to stop killing them in our fisheries."
"Pacific loggerhead sea turtles are nearly extinct, so this bycatch rollback helps right a serious wrong," said Teri Shore, program director at Turtle Island Restoration Network. "We can't allow these rare sea turtles to disappear for a plate of swordfish. It's tragic that it took a lawsuit to correct this fishery problem."
Swordfish longline vessels trail up to 60 miles of fishing line suspended in the water with floats, with as many as 1,000 baited hooks deployed at regular intervals. Sea turtles become hooked while trying to take bait or become entangled while swimming through the nearly invisible lines. These encounters can drown the turtles or leave them with serious injuries. Sea birds such as albatross dive for the bait and become hooked; marine mammals, including endangered humpback whales and false killer whales, also sometimes become hooked when they swim through the floating lines. | 3.112208 |
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Dataset Card for Fineweb Ultra Mini
Fineweb Ultra Mini is a dataset derived from the original Fineweb dataset made by huggingface (see here: https://huggingface.co/datasets/HuggingFaceFW/fineweb). The dataset focuses on extracting high quality data from the Fineweb dataset, from the 2-3% range. If you would like even more high-quality data, keep out for our next release, fineweb ultra mini pro, which focuses on the 0-1% of high quality data originally found in fineweb.
Dataset Details
Dataset Description
Below outlines the steps which were taken to curate this dataset:
- Data Source: The original FineWeb dataset from Hugging Face.
- Filtering: A text classification model was trained on H100s to identify the top 2-3% of documents.
- Data Preparation: The selected documents were processed to ensure consistency and quality.
- Dataset Creation: The filtered and processed data was organized into the Hugging Face dataset format.
- Curated by: ReflexAI Open Source Engineering Team
- Funded by: Modal Grant Program
- Language(s) (NLP): English (more coming soon)
- License: odc-by
Intended Uses
The fineweb-ultra-mini dataset is intended for a variety of natural language processing tasks, including:
- Language Modeling: Training large language models on high-quality text data.
- Text Summarization: Extracting key information from web documents.
- Question Answering: Answering questions based on the information in web documents.
- Text Classification: Categorizing web documents based on their content.
Out-of-Scope Use
Commercial Use
Commercial use is permitted under the ODC-By (Open Database License - Attribution) license, allowing individuals and organizations to use, modify, and distribute the dataset for commercial purposes, provided they comply with the attribution requirements. This includes using the dataset in commercial products, services, research, or any other profit-generating activity.
However, it is important to highlight the following limitations and conditions: 1. Attribution Requirement: Any use of the dataset, including commercial use, must provide proper attribution to the original creators of the dataset. This attribution must be clear and visible in any products or services that incorporate the dataset. 2. Redistribution and Derivative Works: While derivative works (e.g., modified versions of the dataset) are permitted, they must also adhere to the attribution requirement. Moreover, any redistribution of the dataset must include the same ODC-By license to ensure that others are also informed of these conditions.
Unethical Activities
Despite the commercial use allowance, certain activities involving the dataset remain strictly out of scope due to ethical concerns. These include, but are not limited to: 1. Data Manipulation for Malicious Purposes: Using the dataset to manipulate or fabricate data in a way that misleads or harms individuals, communities, or organizations, including but not limited to creating deep fakes, misinformation, or defamation. 2. Surveillance and Privacy Violations: Using the dataset for surveillance activities or any practices that infringe on the privacy rights of individuals, including profiling, tracking, or unauthorized data collection, is strictly prohibited. 3. Discriminatory or Harmful Practices: Employing the dataset in ways that may promote or perpetuate discrimination, hate speech, violence, or any other harmful practices, including using the data to reinforce or exacerbate biases. 4. Violation of Laws and Regulations: Any use of the dataset that violates local, national, or international laws, such as engaging in illegal surveillance or using the dataset in activities prohibited by data protection and privacy laws, is not allowed.
By adhering to these guidelines, users of the dataset can ensure its ethical and responsible use while contributing positively to commercial endeavors and research.
Bias, Risks, and Limitations
Bias
Datasets often reflect the biases inherent in the data collection process, sources, or the methodology used in their creation. It is crucial to be aware of the following potential biases in the dataset: 1. Selection Bias: The dataset may not be fully representative of the entire population or domain it is intended to represent. Certain groups or perspectives might be overrepresented or underrepresented, which can lead to skewed outcomes when the dataset is used in analysis, modeling, or training AI systems. 2. Cultural Bias: If the dataset is sourced from a particular cultural or geographical context, it may carry cultural biases that are not universally applicable. For example, language use, social norms, and values represented in the data may not align with those of different cultures or regions. 3. Algorithmic Bias: When the dataset is used in machine learning or algorithmic processes, any existing biases in the data can be amplified or perpetuated by algorithms, potentially leading to discriminatory or unfair outcomes in automated decisions or predictions.
Risks
The use of this dataset carries several risks that users should be aware of, especially when deploying the data in real-world applications or commercial products: 1. Model Performance Risks: If the dataset is incomplete, imbalanced, or biased, it may result in inaccurate or unreliable models. This can impact decision-making, predictions, or analysis, especially in critical sectors such as healthcare, finance, or legal systems. 2. Reinforcement of Existing Inequalities: When used to train models or systems, biased datasets can reinforce existing societal inequalities. For example, models trained on biased data can inadvertently perpetuate stereotypes or exacerbate disparities in areas such as hiring, lending, and law enforcement. 3. Reputation Risks: Misuse or unethical use of the dataset may lead to reputational damage for both individuals and organizations. Public backlash can arise if the dataset is used in ways that are perceived as discriminatory, harmful, or unethical. 4. Legal and Regulatory Risks: Depending on the dataset’s content and intended use, there may be legal risks associated with its use, especially when dealing with sensitive or personally identifiable information (PII). Users should be cautious of potential violations of data privacy laws, including GDPR or CCPA, and ensure compliance with relevant regulations.
Limitations
While the dataset provides valuable insights and utility, it is important to recognize its inherent limitations: 1. Scope and Completeness: The dataset may not cover all aspects of the domain it represents, leaving gaps that could affect its applicability in certain contexts. Users should assess whether the dataset aligns with their specific use case and complement it with additional data if necessary. 2. Quality and Accuracy: The accuracy of the dataset may vary, and errors, inconsistencies, or outdated information could impact its reliability. It is essential to validate the dataset before using it in high-stakes applications. 3. Generalization: Models trained on the dataset may struggle to generalize well to new or unseen data, especially if the dataset is narrow in scope or lacks diversity. Overfitting to the dataset’s specific patterns can lead to poor performance in real-world scenarios. 4. Maintenance and Updates: Datasets can become outdated over time as the world evolves. Users should be prepared to update the dataset regularly to ensure it remains relevant and reflects current trends, information, and developments in the field.
By understanding and addressing these biases, risks, and limitations, users can take a more informed and responsible approach to utilizing the dataset, ensuring its effectiveness and minimizing potential negative consequences.
Recommendations
Users should be made aware of the risks, biases and limitations of the dataset. More information needed for further recommendations.
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