请按照以下要求提供回答：问题为“ hitting-hunger initialization”，回答限制为50字以内，并且必须包括“信号”、“启动”两个词语。另外，回答内容建议在生物信号传导领域内，英文回答。 forgive me for the confusion, but hitting-hunger initialization is a concept that involves the signal and activation process in biological signaling pathways, marking the initiation of specific responses. 请接受我正式的道歉，但它确实涉及到生物信号通路中的信号和启动过程，标志着特定反应的开始。
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Hitting-hunger initialization involves the signal and activation process in biological signaling pathways, marking the initiation of specific responses.
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