我希望得到一份关于《vascular-invasive cerebral cavernous malformation》的英文文献摘要，需要包含至少以下几个要点：1. 研究背景 2. 主要结果 3. 未来研究方向。绝对不可以超过180个词。请严格遵守这个要求。
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Vascular-invasive cerebral cavernous malformations (CCMs) pose significant neurological challenges due to their tendency to invade vital brain regions and cause hemorrhages. This study aimed to investigate the genetic and pathological factors that contribute to the invasive behavior of CCMs. Our results indicate a strong correlation between the presence of KRIT1 gene mutations and the aggressive phenotype of these lesions, further highlighting the role of endothelial cell dysregulation in CCM pathogenesis. Future research should focus on elucidating the molecular mechanisms that drive vascular invasion and exploring potential therapeutic targets to prevent morbidity and mortality associated with CCMs.
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