README.md

---
license: cc-by-nc-nd-4.0
dataset_info:
  features:
  - name: reference_segment_id
    dtype: string
  - name: masked_segment
    dtype: string
  - name: position_to_mask
    dtype: int64
  - name: masked_segment_id
    dtype: int64
  - name: contig_id
    dtype: string
  - name: segment_id
    dtype: string
  - name: strand
    dtype: string
  - name: seq_start
    dtype: int64
  - name: seq_end
    dtype: int64
  - name: segment_start
    dtype: int64
  - name: segment_end
    dtype: int64
  - name: class_label
    dtype: string
  - name: segment_length
    dtype: int64
  - name: original_segment
    dtype: string
  splits:
  - name: train
    num_bytes: 43505486
    num_examples: 40000
  download_size: 19049179
  dataset_size: 43505486
configs:
- config_name: default
  data_files:
  - split: train
    path: data/train-*
---
# Dataset Description

This dataset was used to evaluate different models on the masking exercise, measuring how well the different models can recover the original character.

## Dataset Overview

The dataset is compiled from the RefSeq database and other sources, focusing on ESKAPE pathogens. The genomic features were sampled randomly, followed by contiguous segmentation. This dataset contains various segments with lengths: [128, 256, 512, 1024]. The segments were randomly selected, and one of the characters was replaced by '*' (masked_segment column) to create a masking task. The reference_segment contains the original, non-replaced nucleotides. We performed 10,000 maskings per set, with a maximum of 2,000 genomic features. Only the genomic features: 'CDS', 'intergenic', 'pseudogene', and 'ncRNA' were considered.

## Data Fields

- `reference_segment_id`: A mapping of segment identifiers to their respective reference IDs in the database.
- `masked_segment`: The DNA sequence of the segment with certain positions masked (marked with '*') for prediction or testing purposes.
- `position_to_mask`: The specific position(s) in the sequence that have been masked, indicated by index numbers.
- `masked_segment_id`: Unique identifiers assigned to the masked segments. (unique only with respect to length)
- `contig_id`: Identifier of the contig to which the segment belongs.
- `segment_id`: Unique identifier for each genomic segment (same as reference segment id).
- `strand`: The DNA strand of the segment, indicated as '+' (positive) or '-' (negative).
- `seq_start`: Starting position of the segment within the contig.
- `seq_end`: Ending position of the segment within the contig.
- `segment_start`: Starting position of the genomic segment in the sequence.
- `segment_end`: Ending position of the genomic segment in the sequence.
- `label`: Category label for the genomic segment (e.g., 'CDS', 'intergenic').
- `segment_length`: The length of the genomic segment.
- `original_segment`: The original genomic sequence without any masking.

## Usage

This dataset is intended for academic and research purposes. Users are encouraged to use this dataset in the development and evaluation of bioinformatics models, especially those related to genomic studies.

## Contact Information

For any questions, feedback, or contributions regarding the datasets or ProkBERT, please feel free to reach out:

- **Name**: Balázs Ligeti
- **Email**: [email protected]

We welcome your input and collaboration to improve our resources and research.



## Citation

```bibtex
@Article{ProkBERT2024,
  author  = {Ligeti, Balázs et al.},
  journal = {Frontiers in Microbiology},
  title   = {{ProkBERT} family: genomic language models},
  year    = {2024},
  volume  = {14},
  URL     = {https://www.frontiersin.org/articles/10.3389/fmicb.2023.1331233},
  DOI     = {10.3389/fmicb.2023.1331233}
}