The treatment of choice for squamous cell anal cancer?
Squamous cell anal cancer is rare but associated with Human papilloma virus infection (HPV), Anal intra-epithelial neoplasia (AIN) and immunosuppression. The current treatment of anal canal carcinoma is chemoradiotherapy (combined modality therapy). Chemotherapy include a combination of 5-FU with mitomycin C or Cisplatin. Ref: Bailey and Love Sho Practice of Surgery, 25th Edition, Page 1269; The MD Anderson Manual of Medical Oncology, 2nd Edition, Chapter 22.
Laser fulgaration
Chemoradiotherapy
Abdominoperennial resection
Platinum-based chemotherapy