All are true about Shigella except:
Ans. is 'a' i.e. Large dose is required for infection. * Shigella is highly communicable .The infective dose for shigella is less. It can be as low as 10 -100 bacilli because they survive gastric acidity better than other enterobacteriae.I had a hard time confirming the choice D.After going through Paniker Page 264 6th/e, Jawetz Page 224 22nd/e, Harrison Page 97615th/e I came to the conclusion that -r<r essential process in the pathogenesis is invasion of the mucosal epithelial cells by the organism through phagocytosis. The production of toxin is also of importance for virulence but main factor is invasion of the Epithelial cells of gut by the organism "REMEMBER: "Non toxigenic mutants can still cause dysentery but not noninvasive one"
Large dose is required for infection
Associated with hemolytic uremic Syndrome
Causes bloody diarrhea with mucus
Gut pathology is due to toxin.
Bacteria