Which is the most common gene mutation responsible for the following thyroid cancer?
The image shows Orphan Annie appearance of cells lining thyroid follicles. This is diagnostic of papillary cancer of thyroid. BRAF V600E mutations are the most common genetic alterations in papillary cancer of thyroid.. P53 is related to anaplastic cancer. Ret is related to medullary cancer of thyroid in patients of MEN type 2. Ras is related to follicular cancer of thyroid> papillary cancer of thyroid.
Ret
Ras
P53
BRAF
Diseases of Thyroid