Which amino acid undergoes hepatic deamination?
Ans: B (Glutamate) Ref: Harper's Illustrated Biochemistry, 26th edition. Pg 244.Explanation:"Since alanine is also a substrate for glutamate aminotransferase, all the amino nitrogen from amino acids that undergo transamination can be concentrated in glutamate. This is important because L- glutamate is the only amino acid that undergoes oxidative deamination at an appreciable rate in liver & kidney. " (Ref: Harper)BIOSYNTHESIS OF UREAUrea biosynthesis occurs in four stages:TransaminationOxidative deamination of glutamateAmmonia transportReactions of the urea cycle
Alanine
Glutamate
Aspartate
Glycine