The first virological marker following acute infection with HBV is :
Answer is A (H Bs Ag): The earliest marker appearing in serum in acute Hepatitis B infection is HBs Ag. After infection the first virological marker detectable in serum is -- HBsAgQ - it precedes elevation of serum aminotransferases as well as clinical symptoms. Q - it remains elevated during the entire icteric or symptomatic phase of acute hepatitis B & beyond. Q Anti Hbs Ag appears only after Hbs Ag has disappeared (occasionally after a gap of several weeks). IgM Anti 14BcAg is demonstrable in serum beginning within 1-2 weeks after the appearance of HBsAg. e HBcAg is sequestrated and not detectable routinely in the serum. Q Anti I-IBe Ag appears sholy before disappearance of Hbs Ag. HBeAg appear concurrently or sholy after HBsAg Q.This too is detectable during the acute phase.
HBs Ag
Anti HBs Ag
IgM anti FIBc Ag
Anti HBe Ag