Which of the following chemotherapeutic agents is associated with secondary leukemia
Alkylating agents bind to DNA and has the potential to introduce mutations. Therefore, these agents can cause sec­ondary leukemias. Procarbazine is most important drug implicated in causation of secondary leukemias.
Cisplatin acts by similar mechanism and can cause leukemia.
Vinblastine
Paclitaxel
Cisplatin
Bleomycin