A pediatric patient with progressively developing degenerative neurologic disease/disorder has an elevated CSF antibody titer to measles virus. You should suspect which of the following?
SSPE is thought to be caused by a measles-related virus present in the central nervous system. Most SSPE patients show elevated measles virus antibodies in serum and CSF. In patients with MS, lower CSF antibody titers have been observed, suggesting a possible etiologic role for measles virus in MS.
Acute Lyme disease
Fifth disease
Possible hepatitis B infection
Possible subacute sclerosing panencephalitis (SSPE)
Immunology