What enzyme is inhibited by etoposide ?
Ans. is 'b' i.e., Topoisomerase(Ref: KDT 7h/e p. 8661)EtoposideSemisynthetic derivative of podophyllotoxin, a plant glycoside'Not a mitotic inhibitor, but arrests cells in the G2 phase and causes DNA breaks by affecting DNA topoisomerase-2 function.
Topoisomerase I
Topoismerase II
Dihydrofolate reductase
Dihydro orotate oxidase