In pregnancy with increased MSAFP which of the following should be done:
MSAFP is a screening test. If it is raised, it should be followed by a diagnostic test, i.e. either USG or amniocentesis as discussed earlier, these days for diagnosis of NTD, USG has replaced amniocentesis, hence answer is USG.
Repeat measurement of MSAFP at later date
USG
Amniocentesis
Termination of pregnancy