Following liver transplantation, recurrence of primary disease in the liver most likely occurs in -
Ans. is 'b' i.e., Autoimmune hepatitis In the question, recurrence is suspected in the following three options -Autoimmune hepatitisPrimary sclerosing cholangitisPrimary biliary cirrhosis Autoimmune hepatitisAutoimmune hepatitis recurs in 1/3 of patients Sclerosing cholangitis "Whether autoimmune hepatitis and sclerosing cholangitis recur after liver transplantation is controversial, datas supporting recurrent autoimmune hepatitis are more convincing than those supporting sclerosing cholangitis".Primary biliary cirrhosis "Results of liver transplantation for PBC are excellent, survival exceeding that for patients receiving transplantation for most other forms of end stage liver disease. Recurrence of PBC after liver transplantation has been reported but is uncommon and the recurrent disease is only slowly progressive"More on liver transplantationWilson's disease and a antitrypsin deficiency do not recur after transplantation.Most common cause of recurrence after liver transplantation is - chronic hepatitis C.
Wilson's disease
Autoimmune hepatitis
Alpha-1 antitrypsin deficiency
Primary biliary cirrhosis
G.I.T.