A young man presented with hyper parathyroidism. Which of the following radionuclide scan is done for parathyroid adenoma?
The localization ability of Technetium 99m sestamibi scintigraphy is based on its preferential uptake by parathyroid cells, due to their high mitochondrial activity. Delayed images taken 2 to 3 h after injection are sensitive in up to 90% of single adenoma cases, with over 90% specificity. Sestamibi imaging is also effective in cases of double adenoma. However, it has significantly reduced accuracy in cases of four-gland hyperplasia. Ref: Singer M.C., Terris D.J. (2012). Chapter 43. Parathyroid Disorders. In A.K. Lalwani (Ed), CURRENT Diagnosis & Treatment in Otolaryngology--Head & Neck Surgery, 3e.
Sesta MIBI scan
Iodine-123 scan
99mTc-sulphur colloid
Gallium scan