Which of the following statements about Rheumatoid Factor is true ?
In rheumatoid ahritis it is suspected that antibodies plays a role in the disease. About80% of patients have serun IgM autoantibodies that bind to fc poion of their own self IgG. These antibodies are called rheumatoid factor. Ref :Robbins basic pathology 9th edition page no 784,green box=Pathogenesis
It is an IgM antibody directed against IgG
It is an IgG antibody directed against 1gM
It is more specific than Anti-CCP antibodies
It is positive in all cases of Juvenile Rheumatoid Ahritis
Breast