Saroj, a 32-year-old female, from rural background presented with a h/o chronic tobacco chewing since 14 years of age. Now she has difficulty in opening her mouth. On oral examination, no ulcers are seen - Most probable diagnosis is -
" Submucous oral fibrosis is a progressive ds. in which fibrous bands form beneath the oral mucosa. These bands progressively contract so that ultimately mouth opening is severely limited. Tongue movements may also be limited. 
This condition is almost entirely confined to Asians. Histological it is characterized by juxtaepithelial fibrosis with atrophy or hyperplasia of the overlying epithelium which also shows areas of epithelial dysplasias. The etiology is obscure. Hypersensitivity to chilli; betel nut, tobacco and vitamin deficiencies have been implicated.
The scar bands of submucous fibrosis, which result in difficulty in opening can be treated either by intralesional injection of steroids or by surgical excision and grafting, but this has little effect in preventing the onset of squamous cell Ca in the generally atrophic oral mucosa (Submucous oral fibrosis is a precancerous condition for squamous cell Ca)." - Bailey & Love
Submucous oral fibrosis
Carcinoma of buccal mucosa
TM joint arthritis
Trigeminal nerve paralysis