Laudanosine is a metabolite of:
Ans. (A) Atracurium(Ref: Miller 7th/e p880)Both atracurium and cis-atracurium are eliminated by Hoffman's elimination. Atracurium is also metabolized by liver to some extent and result in production of a metabolite, laudanosine that can cause CNS toxicity including seizures. On the other hand cis-atracurium is almost completely eliminated by Hoffman's elimination and produce negligible laudanosine.
Atracurium
Cis-atracurium
Pancuronium
Vecuronium
Anaesthesia