Absence of Corpus callosum leads to-
Ans. is 'd' i.e., No neurological manifestations o Agenesis of corpus callosum is a rare birth defect (congenital disorder) in which there is complete or partial absence of corpus callosum.o Corpus callosum is a band of tissue connecting the two hemispheres of the brain. Fibres of corpus callosum arise from the superficial layers of the cerebral cortex and they project to the homotypic regions of the contralateral cortex by passing through the corpus collosum while crossing the midline.Clinical features of Agenesis of corpus callosum:-o Signs and symptoms of agenesis of corpus callosum vary greatly among individuals.o "Patients usually do not have any neurological manifestations".o However, some features common in agenesis of corpus callosum are# Vision impairment# Low muscle tone (hypotonia)# Poor motor coordination# Delay in motor milestones such as sitting and walking.# Low perception of pain# Delayed toilet training# Chewing and swallowing dijficulties# Early speech and language delays# Social difficultieso Other characteristics sometimes associated with callosal disorders are# Seizures# Spasticity# Early feeding difficulties and or gastric reflux# Hearing impairments# Abnormal head and facial features# Mental retardationInvestigationo CT and MRI reveals "Bat wing" deformity of the ventricles.Treatmento There are currently no specific medical treatments for callosal disorders.
Hemiparesis
Hemisensory loss
Astereognosis
No neurological manifestations
Miscellaneous (C.N.S.)