Carboxypenicillins true is all except -
Ans. is 'a' l.e., Nephrotoxic Carboxvpeniciilins - Carbenicillin:o It is active against pseudomonas and indole positive proteus.o Klebsiella and gram positive cocci are unaffected by ito It is neither penicillinase resistant nor acid resistant,o It is inactive orally and is rapily excreted in urine in 1 hr.o At high doses it can cause bleeding by interfering with platelet function due to perturbation of agonists receptors on platelet surface.# Carbenicillin indanyl is an orally active ester of carbenicillin, used for treatment of UTI caused by pseudomonas and proteus.
Nephrotoxic
Sensitive to penicillinase
Effective against pseudomonas
Platelet aggregation affected
Penicillin & Cephalosporin