A five year old boy presents with precocious pubey and a Blood pressure of 130/80 mm Hg. Estimation of which of the following will help in diagnosis
Determining the type of precocious pubey Your child&;s doctor will also need to find out which type of precocious pubey your child has. To do so, he or she will perform a test called a gonadotropin-releasing hormone (GnRH) stimulation test. In this test, the doctor will take a blood sample, and then give your child a shot containing the GnRH hormone. More blood samples are then taken over a ceain period of time to check how hormones in your child&;s body react. In children with central precocious pubey, the GnRH hormone will cause other hormone levels to rise. In children with peripheral precocious pubey, other hormone levels stay the same. Additional testing for central precocious pubey Magnetic resonance imaging (MRI). A brain MRI is usually done for children who have central precocious pubey to see if any brain abnormalities are causing the early sta of pubey. Thyroid testing. The doctor may also test your child&;s thyroid if he or she shows any signs of slow thyroid function (hypothyroidism), such as fatigue, sluggishness, increased sensitivity to cold, constipation, a drop in school performance or pale, dry skin. Additional testing for peripheral precocious pubey Other tests also are necessary for children with peripheral precocious pubey to find the cause of their condition. For example, the doctor may run additional blood tests to check other hormone levels or, in girls, he or she may do an ultrasound to check for an ovarian cyst or tumor. Reference: GHAI Essential pediatrics, 8th edition
17 hydroxy - progesterone
Coisol
Aldosterone
11 deoxycoisol
Endocrinology