Regarding leprosy true is
(D) Sensitive to INH and Rifampicin # LEPROSY, is a nonfatal ] chronic infectious disease caused by Mycobacterium leprae: the clinical manifestations of which are largely confined to the skinL peripheral nervous system 3 upper respiratory tract, eyes, and testis.> M. leprae remains one of the few bacterial species that still has not been cultivated on artificial medium or tissue culture.The multiplication of M. leprae in mouse footpads.> AFB are generally absent or few in number in tuberculoid leprosy.> WHO recommends that pauci bacillary adults be treated with 100 mg of dapsone daily and 600 mg of rifampin monthly (supervised) for 6 months.> Multibacillary adults should be treated with 100 mg of dapsone plus 50 mg of clofazimine daily (unsupervised) and with 600 mg of rifampin plus 300 mg of clofazimine monthly (supervised).> WHO recommended that lepromatous patients be treated for 2 years or until smears became negative (generally in -5 years); subsequently the acceptable course was reduced to 1 year.
Lives in parts of body where temperature is <37 degrees
Can grow in cell free culture media
Can be seen in biopsies in tuberculoid leprosy
Sensitive to INH and Rifampicin
Miscellaneous