Worldwide accepted minimum dose of Benzathine penicillin in Teiary syphilis?
Recommendations for the Treatment of Syphilis Stage of Syphilis Patients without Penicillin Allergy Patients with Confirmed Penicillin Allergy Primary, secondary, or early latent Penicillin G benzathine (single dose of 2.4 MU IM) Tetracycline hydrochloride (500 mg PO QID) or Doxycycline (100 mg PO BID) for 2 weeks Late latent (or latent of unceain duration), cardiovascular, or benign teiary Lumbar puncture CSF normal: Penicillin G benzathine 2.4 MU IM weekly for 3 weeks(total of 7.2 MU) CSF abnormal: Treat as neurosyphilis Lumbar puncture CSF normal and patient not infected with HIV: Tetracycline hydrochloride (500 mg PO QID) or Doxycycline (100 mg PO BID) for 4 weeks CSF normal and patient infected with HIV: Desensitization and treatment with penicillin if compliance cannot be ensured CSF abnormal: Treat as neurosyphilis Neurosyphilis (asymptomatic or symptomatic) Aqueous penicillin G (18- 24 MU/d IV, given as 3-4 MU 4h or continuous infusion) for 10-14 days or Aqueous penicillin G procaine (2.4 MU/d IM) plus oral probenecid (500 mg QID), both for 10-14 days Desensitization and treatment with penicillin Syphilis in pregnancy According to stage Desensitization and treatment with penicillin
4.8 Milion IU
6 Million IU
7.2 Million IU
10 Million IU
Sexually Transmitted Infections