Furosemide acts to inhibit Na + reabsorption in which of the following locations
HIGH CEILING (LOOP) DIURETICS (Inhibitors of Na+ K+ 2Cl- Cotranspo) Furosemide (Frusemide):- The major site of action is the thick AscLH (therefore called loop diuretics) where furosemide inhibits Na+- K+-2Cl- cotranspo. A minor component of action on PT has also been indicated. It is secreted in PT by organic anion transpo and reaches AscLH where it acts from lluminal side of the membrane. Ref:- kd tripathi; pg num:-579
Descending limb of the loop of Henle
Distal convoluted tubule
Collecting duct
Ascending limb of the loop of Henle
Kidney