Each of the following is true about the idiopathic primary pulmonary hypeension except
Idiopathic pulmonary aerial hypeension can be sporadic or familial with autosomal dominant inheritance.Heterozygous germ-line mutations involving the gene that code for type ll bone morphogenetic protein receptor(BMPR ll),a member of the transforming growth factor beta superfamily,appear to account for most cases of familial IPAH. There is a female predominance,with most patients presenting in the fouh and fifth decades.The disease typically is diagnosed late in its course.Before current therapies,a mean survival of 2-3 years from the time of diagnosis was repoed. Ref:Harrison' s medicine-18th edition,page no:2077,2078.
It is usually associated with coronary aery disease
It is more common in females
It is usually asymptomatic to begin with
It is characterized by autosomal dominant inheritance
Respiratory system