All are true regarding GnRh analogues except
GnRH Pulsatile GnRH analogues used for delayed pubey Continuous administration is DOC for precocious pubey GnRH analogues may be used for Controlled Ovarian Hyperstimulation in IVF cycles. When used in pulsatile manner, it causes oocyte recruitement. When used in continuous manner, causes controlled hyperstimulation by pituitary suppression. Side effects: Hyperstimulation syndrome Multiple pregnancy is the same as in the general population Aboion rate may be slightly increased Hypoestrogenic state Menopausal symptoms Osteoporosis ( prolonged use more than 6 months ) First line management of Menorrhagia - NSAIDs & Tranexamic acid
Drug of choice for precocious pubey
Side effect is Osteoporosis
Can be used for Controlled Ovarian Hyperstimulation for IVF
First line management of menorraghia
Normal Menstruation, Abnormal Menstruation, Menopausal Physiology and forsight of conception