Nitroglycerine is effective when administered sublingually because it is:
Ans. (A) Non ionized and lipid soluble(Ref: KDT 8th/e p28)Nitroglycerin is effective when retained sublingually because it is non-ionized and has very high lipid solubility. Thus, the drug is absorbed very rapidly.
Non ionized and lipid soluble
Ionized and lipid soluble
Non ionized and Water insoluble
Ionized and water insoluble
General Pharmacology