NOT True about Gout
C. i.e. (Not found in woman after menopause) (2165 - H17th) (69 - Apley 8th) (714-CMDT 09)GOUT* Purine metabolic disease affecting middle aged to elderly men and post menopausal women*** Deposition of monosodium urate (MSU) crystals** in the joints and connective tissue tophi* Much commoner in Caucasian than in black African people* Late changes include cartilage degeneration, renal dysfunctions and uric acid urolithiasis* Precipitating factors - minor trauma, operation, intercurrent illness, unaccustomed exercise or alcohol* Commonest site are the metatarsophaangeal joint of the big toe**, the ankle and finger joints and olecranon bursae* Definitive diagnosis - characteristic negatively birefringent urate crystal in the synovial fluid*** Hyperuricemia is not diagnostic and is often seen in normal middle age men* Uric acid kidney stones are present in 5 - 10% of patients with gouty arthritis* Patients with gout are anecdotally thought to have an increased incidence of hypertension, renal disease (eg nephrosclerosis, interstitial nephritis pyelonephritis) DM, hypertriglyceridemia and atherosclerosis
Uncommon in vegetarian
Uncommon in tallotellers
Not found in women after menopause
Not common renal disorders
Immunology and Rheumatology