All the following statements are true for rabies virus except:
Rabies vaccine is a killed vaccine. Option 1 Both active and passive immunization is recommended for grade III exposure to prevent infection. Option 2 The animal reservoir differs from country to country, in India it is dog. Rabies is a zoonotic disease. Other animal reservoirs include silver-haired bats, eastern pipistrelle, raccoons, skunks, foxes, or cats, ferrets, cattle, opossums, fowl, etc. Foxes are more infectious than dogs and other animals. Option 3 Direct fluorescent antibody test of corneal impression smear or hair follicle of nape of neck is the ideal method of antemoem diagnosis of rabies. Option 4 Rabies Vaccine: 1. Neural Vaccines: They are poorly immunogenic and encephalitogenic; hence not used. Semple vaccine: Derived from infected sheep brain BPL: Beta propiolactone derived vaccine (Prepared in Coonoor) Infant mouse brain derived vaccine 2. Non-neural Vaccines: Cell line derived, they are the recommended killed vaccine currently: Purified chick embryo cell (PCEC) Purified Vero cell (PVC) Human diploid cell (HDC).
Infection may be prevented by active and passive immunization
The animal reservoir differs from country to country
Diagnosed by DFA
Rabies vaccine is a live attenuated vaccine
Virology Pa-2 (RNA Virus Pa-1,2 & Miscellaneous Viruses)