Which of the following is the mechanism of action of new drug Rhopressa for glaucoma treatment
Increased trabecular meshwork outflow is the mechanism of action of new drug Rhopressa (rho- kinase inhibitors) New Drugs in Glaucoma Anecorvate - Angiostatic steroid. Ethacrynic acid latrunculins - cellular cytoskeletal modulators. Alter TM shape. Olmesean, lomerizine, nivaldipine - improves vascular perfusion. Neurotropic- FGF ,increase ganglion cell life. Memantine : NMDA antagonist. Rho kinase inhibitors increase TM outflow.
Increased uveoscleral outflow
Increased trabecular meshwork outflow
Increased aqueous production
Decreased aqueous production
Glaucoma