Following are the advantages of sustained release preparation over the conventional preparations except ?
Ans. is 'd' i.e., Drugs with half life > 4 hours are suitable Acts for a longer period. Frequency of administration is reduced -more convenient. Improved patient compliance - a single morning dose is less likely to be forgotten/omitted than a 6 or 8 hourly regimen; a monthly or quaerly administered contraceptive over one that has to be taken daily. Large fluctuations in plasma concentration are avoided. Side effects related to high peak plama level just after a dose (e.g. nifedipine) would be minimized. Better round-the-clock control of blood sugar, etc. Drug effect could be maintained overnight without disturbing sleep, e.g. antiasthmatics, anticonvulsants, etc.
Decreased frequency of administration
Improved compliance
Less incidence of high peak side effects
Drugs with half life > 4 hours are suitable