What is the dose of Isoniazid to be safely used in children?
Dose of Isoniazid in children is 10-20mg/kg when given daily. Maximum dose is 300mg/d. When given twice or thrice, weekly dose is 20-40mg/kg maximum of 900mg. Dose of rifampicin in children: 10-20mg/kg (max 600mg) Dose of pyrazinamide: 15 - 30mg/kg (max 2g) Dose of ethambutol: 15 - 25mg/kg (max 1.5g) Dose of streptomycin: 20 - 40mg/kg (max 1g) Ref: Oxford Textbook of Medicine: Infection edited by David Warrell, page 441
5 mg/kg
10-20 mg/kg
15-25 mg/kg
20-40 mg/kg