Renal aery stenosis may occur in all of the following, except :
Answer is D (Polyaeritis nodosa) Amongst the options provided renal aery stenosis is least likely to be seen in association with Polyaeritis nodosa. Atherosclerosis and Fibromuscular disease - Renal aery stenosis is produced predominantly by atherosclerotic occlusive disease (80% to 90% of patients) or tibromuscular dysplasia (10-15% of patients).- CMDT'06 p 460 - he common cause of renal aery stenosis in the middle aged and elderly is an atheromatous plaque at origin of renal aery. Harrison - In younger women stenosis is due to intrinsic structural abnormalities of the aerial wall caused by a heterogenous group of lesions called 'fibromuscular dysplasia'. - Harrison 16`" /1707 PAN or Takayasu aeritis ? CMDT do not mention PAN or Takayasu aeritis as a cause for renal aery stenosis. However, Takayasu aeritis is ceainly a more common cause of renal aery stenosis than PAN. Takayasu aeritis (Aoo-aeritis) is beleiveds to be the most common of renovascular hypeension in India and China. - Diseases of Kidney and Urinary Tract 8th/1279 A number of research publications, however show Takayasu aeritis as a cause for renal aery stenosis. PAN Although renal involvement is seen in upto 60% of patients with PAN its pathology does not involve renal aery stenosis. The pathology involves aeritis without glomerulonephritis and is characterised by aneurysms of small and medium sized aeries. Stenosis of main renal aery is an unusual association'. Causes of Renal aery stenosis : Atherosclerosis Fibromuscular dysplasia Non specific Aoo aeritis Takayasu aeritis and giant cell aeritis (Takayasu > Giant cell) Antiphospholipid syndrome Transplant renal aery stenosis Renal aery embolism Dissecting aneurysm of aoa Radiation aeritis
Atherosclerosis
Fibromuscular dysplasia
Takayasu's aeritis
Polyaeritis nodosa