Coagulative necrosis is seen ill
Ans. is ' a' i.e., Gangrene > Tuberculosis "Gangrene (Dry) occurs as a result of ischaemic coagulative necrosis of tissues due to aerial obstruction". "Caseous necrosis (occuring in TB) is a distinctive forms of coagulative necrosis but unlike a coagulative necrosis the tissue architecture is completely obliterated". - Robbins illustrated (basis), 6/e, p17. o Thus both gangrene and tuberculosis are variants of coagulative necrosis. You may choose your answer. Gangrenous necrosis o Gangrenous necrosis is of two types:? Dry gangrene Wet gangrene Dry gangrene It is a clinically distinct variant of coagulative necrosis. It occurs most commonly in the soft tissue of lower limbs (Leg, foot, toes) as a result of ischemia due to aerial occlusion, that leads to coagulative necrosis. Then, why is it called gangrenous necrosis not coagulative necrosis ? Lets see. Since the extent of vascular occlusion is frequently global in the lower limbs, which impedes or prevents the migration of leukocytes in to the area of coagulative necrosis, it is called gangrenous necrosis because the dead tissue is not digested and removed but remains mummified. Wet gangrene o When overlying skin of dry gangrenous tissue is devitalized, bacterial infection is superimposed and the coagulative necrosis is modified by liquifactive necrosis. So, o Dry gangrene --> Variant of Coagulative necrosis. Wet gangrene --> Liquifactive necrosis is superimposed on coagulative necrosis.
T.B.
Sarcoidosis
Cryptococcal infection
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