A patient suspected of both gonococcal and non gonococcal urethritis. Drug of choice in such patient?
Ans. b. Azithromycin 2 gm statMonotherapy with 2 g oral azithromycin has been proven to be effective in patients with noncomplicated gonorrheal infections, but this is no longer recommended because of concerns of resistance to macrolides and documented treatment failures.Given the growing resistance patterns of gonorrhea, dual antibiotic therapy is recommended for treatment. First line recommendations for uncomplicated gonococcal infection of the vagina, cervix or rectum are "ceftriaxone 250 mg IM once plus azithromycin 1 g orally once". In cases of gonococcal conjunctivitis or disseminated gonococcal infections, the dose of ceftriaxone should be increased to 1 g IM single dose plus 1 g oral azithromycin once. A single 2 g oral dose of extended-release azithromycin for treatment of gonococcal urethritis.Ref. Journal of Antimicrobial Chemotherapy, Volume 69, Issue 11, 1 November 2014. Pages 3116-3118.
Cefixime 400 mg stat
Azithromycin 2 gm stat
Ceftriaxone 250 mg stat
Doxycycline 100 BD
S.T.D.