Hemoglobin H disease is caused by deletion
Ans. (c) Three a globin chains(Ref: Robbins 9th/pg 638)Classification of a-thalassemia:Normally 4 a-genes synthesize: 2 a chains -> a, a / a, aMost common cause of a -thalassemia is a -gene deletion (frame-shift mutation)9
Single a globin chain
Two a globin chains
Three a globin chains
All a globin chain
Misc. (R.B.C)