A farmer with long history depression on antidepressants, consumed unknown substance and presented with bradycardia, hypersalivation, small pupils. What is the most probable diagnosis?
Ans: A (OP poisoning) Ref: Harrison's Principles of internal Medicine. 18th edn.Explanation:MiosisMydriasisCholinergicsAnticholinergicsAntipsychoticsSympathomimeticsCarbamatesSSRIsOrganophosphatesSedative - hypnotics withdrawalOpioidsAlcohol Withdrawal syndromeClonidine Sedative - Hyponotics Clinical Features of Orqanophosphate PoisoningMuscarinic effectsCVS: Bradycardia , HypotensionResp: Rhinorrhea. Bronchorrhea,BronchospasmGIT: Hypersalivatioa Nausea and Vomiting, Abdominal pain. Diarrhea,Fecal incontinence. Urinary incontinenceOcular: Miosis, Blurred vision Glands: Increased lacrimation, DiaphoresisNioctinic effectsMuscle fasciculationsCrampingWeaknessDiaphragmatic paralysis Autonomic nicotinic effects(Mild): Tachycardia, Hypertension, Mydriasis and pallorCNS effectsAnxietyEmotional labilityRestlessnessConfusionAtaxiaT remorsSeizuresComa
OP poisoning
Atropine
TCA
Paracetamol poisoning
Toxicology