Ceruloderma is characterised by-
Ceruloderma- Due to defect in migration of melanocyte. Melanocyte derived from neural crest and migrate to stratum basale (epidermis) Defect in migration of melanocytes due to which they remain in dermis Eg. Of Ceruloderma - 1. Mongolian spot 2. Nevus of OTA3. Nevus of ITO Clinical features - Dermis- Blue lesion - Don't become dark under wood's lamp . Blue d/t - Tyndall effect/optical effect i.e. paial scattering of light Most of light reflected back is blue in colour.
Excess melanin in dermis , pigmentation not accentuated under Wood's lamp
Excess melanin in basal and suprabasal layers, pigmentation accentuated under Wood's lamp
Increased epidermal and dermal melanin
Excess melanin in basal and suprabasal layers, pigmentation not accentuated under Wood's lamp
Hyper Pigmented Disorders