Enzyme deficiency in McArdle syndrome
Glycogen storage disorderTypeNameEnzyme DeficiencyClinical FeaturesType VMyophosphorylase deficiency,McArdle syndromeMuscle phosphorylasePoor exercise tolerance; muscle glycogen abnormally high(2.5%-4%); blood lactate very low after exerciseRef: Harper&;s Biochemistry; 30th edition; Table 18-2; Chapter 18; Metabolism of Glycogen
Muscle phosphorylase
Liver phosphorylase
Liver debranching enzyme
Glycogen synthase
Metabolism of carbohydrate