In deciding on a treatment for a 60 years old patient, Golu, who has chronic hea disease and rheumatoid ahritis, you wish to give him procainamide. He is already taking digoxin, hydrochlohiazide and potassium supplementation. Which of the following is a relevant statement?
(Ref: KDT 6/e p512) Hyperkalemia increases the toxicity of class Ia antiarrhythmics.
A possible drug interaction with digoxin suggests that digoxin blood levels should be obtained before and after staing procainamide.
Hyperkalemia should be avoided to reduce the likelihood of procainamide toxicity
Procainamide cannot be used if the patient has asthma because it has a beta blocking effect
Procainamide is not active by the oral route
Other topics and Adverse effects