A premature infant is more likely than a full-term infant to –
The liver of premature (preterm) neonate is functionally immature that leads to hypoglycemia, hyperbilirubinemia (jaundice) and poor detoxification of drugs.

Problems of preterm Premature babies

Birth asphyxia                                           
Hypothermia                                                                                           
Feeding difficulties                                             
Infections                                                                    
Respiratory distress      
ARDS (Hyaline membrane dis)     
Hyperbilirubinemia     
Apenia   
Intraventricular haemorrhage    
Hypocalcemia 
Necrotising enterocolitis  
Metabolic acidosis
Hypoglycemia
Hypoproteinemia

Note - Problems of preterm small for date babies include problems of both i.e. problems of preterm and problems of small for date.
Suffer from jaundice of hepatic origin
Maintain in normal body temperature in a cold environment
Excrete urine with a uniform specific gravity
Suffer from anaemia