How does metalloproteins prevent the development of jaundice?
Metalloproteins like Tin (Sn) and zinc (Zn) porphyrins and mesoporphyrins are under investigation for clinical use. These compounds inhibit the activity of heme oxygenase and thus decrease the formation of bilirubin, therby preventing the development of jaundice. Ref: Essential of PediatricsBy O P Ghai, 6th Edition, Page 173; Oxidative Stress and Free Radical Damage in Neurology By Natan Gadoth, Page 70.
Decreasing RBC lysis
Inhibiting heme oxygenase
Increasing Y and Z receptors
Increasing glucoronyl transferase activity