Insulin-like Growth factor II plays an impoant role in
The insulin-like growth factor II (IGF-II) internal ribosome entry site IRES is found in the 5&; UTR of IGF-II leader 2 mRNA. This RNA element allows cap-independent translation of the mRNA and it is thought that this family may facilitate a continuous IGF-II production in rapidly dividing cells during development.Ref: Ganong&;s review of medical physiology; 24th edition
Control of metablism
Skeletal growth
Cailage growth
Devolopment of foetus
Endocrinology