Which of the following anti TB drugs acts on extracellular organisms and is bactericidal drug?
Streptomycin is the only anti-TB drug which acts on extracellular organisms and is bactericidal. All first line antitubercular drugs are bactericidal except ethambutol which is bacteriostatic. Impoant points about first line ATT: Drug Action Hepatotoxic Bacteria Inhibited Isoniazid CIDAL Yes Both Rifampicin CIDAL Yes Both Pyrazinamide CIDAL Yes Intracellular Ethambutol STATIC No Both Streptomycin CIDAL No Extracellular
Isoniazid
Streptomycin
Rifampicin
Ethambutol
Mycobacterial Diseases (TB, Leprosy and MAC)