Conn's syndrome is most commonly associated with:
Answer is A (Coical adenoma): Conn's syndrome by defination refers to primary aldosteronism secondary to an aldosterone producing adrenal adenoma. The most common aldosterone producing adrenal tumor is a unilateral adrenal adenoma. Adrenal carcinoma is a rare cause of primary aldosteronism. Primary Aldosteronism secondary to bilateral coical hyperplasia is not defined as Conn's syndrome. Primary Aldosteronism Associated Adrenal Tumor Adrenal Adenoma (Conn's syndrome) Adrenal carcinoma (Rare cause) According to Harrisons 17th edition the most common cause of Conn's syndrome is an aldosterone producing adrenal adenoma. Most cases are unilateral() with a smallQ adenoma which may occur on either side. Without Associated Adrenal tumor Bilateral Coical Hyperplasia (Idiopathic Hyperoldosteronism)/Nodular hyperplasia) According to Harrisons I7th edition the most common cause for primary Hyperaldosteronism is Bilateral coical Hyperplasia. `These patients constitute 80% of patients with Primary Hyperaldosteronism' (Harrison)
Coical adenoma
Coical hyperplasia
Coical carcinoma
Pheochromocytoma