Mannitol decreases the intraocular pressure by ?
Ans. is 'a' i.e., Withdrawing water from vitreous By osmotic action mannitol encourages movement of water from aqueous humour --> decrease. Mannitol is used in angle closure (narrow angle, acute congestive) glaucoma. Treatment of acute congestive glaucoma o Definitive therapy is surgery (laser iridotomy) Drugs are used to decrease the i.o.t. during an acute attack. o Approch is : Sta i.v. mannitol or i.v. acetazolamide When i.o.t. stas falling, sta topical pilocarpine or b -blocker (timolol). Apraclonidine/latanoprost may be added. Once i.o.t. is reduced, surgery is done.
Withdrawing water from vitreous
Increasing uveoscleral outflow
Increasing aqueous through trabecular meshwork
Inhibiting the enzyme carbonic anhydrase in the ciliary body