Aldose reductase inhibitor drugs are useful in
Ans. is 'b' i.e., Diabetes mellitus Aldose reductase catalyzes the NADPH-dependent conversion of glucose to sorbitol, the first step in polyol pathway of glucose metabolism. Aldose reductase inhibitors are a class of drugs being studied as a way to prevent eye and nerve damage in people with diabetes mellitus. Examples of aldose reductase inhibitors include: Tolrestat (withdrawn from market) Apalrestat Ranirestat Fidarestat
Cataract
Diabetes mellitus
Hereditary fructose intolerance
Essential fructosuria