Hybridoma cell line is a product of fusion
The B cells are mixed with mouse myeloma cells and exposed to polyethylene glycol, which causes cell fusion. The product of this fusion is a permanentcell line called a hybridoma capable of providing a continuous supply of monoclonal antibodies.Ref: Harper&;s biochemistry; 30th edition; Chapter 52; 52 Plasma Proteins & Immunoglobulins
B cells with mouse myeloma cells
T cells with mouse myeloma cella
B cells with Guinea pig myeloma cells
T cells with guinea pig myeloma cells
miscellaneous