Pneumocystis carinii is a fungus because ?
Ans. is 'a' i.e., rRNA, Mitochondrial protein gene sequence & presence thymidylate synthase; `b' i.e., Cell wall contains glucans; 'c' i.e., Antifungals are effective against p. carinii . The taxonomic classification of Pneumocystis as a fungus is based on factors: 1. Analysis of gene sequence for ribosomal RNA, mitochondria! proteins and major enzymes. 2. Presence of b-1, 3 glucan in the cell wall. 3. The efficacy of antifungal drugs that inhibit b-glucan synthesis. . In contrast to most fungi. 1. Pneumocystis lacks ergosterol 2. Not susceptible to antifungal drugs that inhibit ergosterol synthesis.
rRNA, mitochondrial protein gene sequence & presence of thymidylate synthase
Cell wall contains glucans
Angifungals are effective against P. carini
All