Rate limiting step in cholinergic transmission ?
Ans. is'b'i.e., Active uptake of choline in axonsAcetylcholine synthesis and releaseCholine is actively taken up by the axonal membrane by Na*; choline cotranspoer. (Rate limiting step). This step is blocked by Hemicholinium.
Synthesis of acetylcholine from choline
Active uptake of choline in axons
Active uptake of acetylcholine by synaptic vesicle
Release of acetylcholine from synaptic vesicle