Which drug has ceiling effect -
Ans. is 'd' i.e., Buprenorphine Ceiling effects o A paicular effect of drug increases with increasing the dose of drug. However, with some opioids (paicularly agonist-antagonist) when the ceiling (roof) is reached fuher increment in dose not result in increase in effect. Ceiling effect is paicularly seen on respiratory depression, i.e., higher doses do not produce fuher respiratory depression.
Morphine
Pethidine
Fentanyl
Buprenorphine