A lung biopsy of a HIV patient showed intra nuclear basophilic inclusion bodies with perinuclearhalo.The patient's CD4 was les then 100 at the time of diagnosis. What is the probable cause?
Cytomegalovirus (CMV) is a double-stranded DNA virus in the herpes virus family that can cause disseminated or localized end-organ disease in HIV-infected patients with advanced immunosuppression. Retinitis is the most common clinical manifestation of CMV end-organ disease in HIV-infected patients. Laboratory tests will be done on a sample of tissue taken from your stomach or intestine. The tests, such as a gastric or intestinal ,lungtissue culture or biopsy, determine if the virus is in the tissue. A CMV serology test is done to look for antibodies to the CMV virus in your blood Ref Harrison20th edition pg 987
CMV
MAC
Pneumocystis
TB
Infection