The given below histology is an example of:
Ans. b. FibroadenomaBENIGN TUMORS OF BREASTFibroadenomaMost common in women <35 years old.Small, well-defined, mobile mass.Fig. 3: Mobile massIt causes a palpable, round, movable, rubbery mass, which on cross-section shows small, cleft-like spaces.Microscopically, the mass shows proliferation of benign stroma, ducts, and lobules.Increases the size and tenderness with the increasing of estrogen level (eg, pregnancy, prior to menstruation).Risk of cancer is usually not increased.Intraductal PapillomaIntraductal papilloma commonly presents as a bloody nipple discharge.Small papillary tumor within lactiferous ducts, typically beneath areola; the myoepithelial layer is preserved.Slight (1.5-2x) increases risk for cancer.Phyllodes tumor (cystosarcoma phyllodes)It usually involves an older patient population (age 50s) and can be benign or malignant.Local recurrence is common but the incidence of metastasis is low.Large mass of connective tissue and cysts with "leaf-like" lobulations.Fig. 4: Large massFig. 5: "Leaf-like" lobulationsMicroscopically, the mass shows increased stromal cellularity, clefts lined by epithelium, stromal overgrowth, and irregular margins.Some may become malignant.
Phyllodes tumor
Fibroadenoma
Intraductal papilloma
Rhabdomyosarcoma
Breast