A 40 year old male developed persistant oral ulcers followed by multiple flaccid bullae on trunk and extremities. Direct immunofluorescence examination of a skin biopsy showed intercellular IgG deposits in the epidermis. The most probable diagnosis is:
It is an autoimmune intraepidermal blistering disease due to antibodies against desmoglein 3. It begins as painful oral erosions followed by flaccid blisters on the trunk, face, scalp. Ref: Current Literature Dermatology By Pasricha, Pages 197, 202; Rook's Textbook of Dermatology, 8th Edition.
Pemphigus vulgaris
Bullous Pemphigoid
Bullous Lupus erythematosus
Epidermolysis bullosa acquisita