True about Cryptococcus neoformans is A/E:
Cryptococcal gelatinous capsule stains bright pink with mucicarmine stain and discriminates the organism from histoplasma and blastomycosis. India ink stain paicles are extruded by the gelatinous capsule and hence only the background is stained. In cryptococcal meningitis, CSF examination reveals evidence of chronic meningitis with mononuclear cell pleocytosis and increased protein levels. Cryptococcal antigen (CRAg) detection in CSF and blood is based on serologic detection of cryptococcal polysaccharide and is both sensitive and specific. Cryptococcus neoformans :Common in immunocompromised patient
Capsule excludes India ink paicles
Common in immunocompromised patient
Anti-capsular antibody prevents recurrence
Strongly positive Mucicarmine stain of the organism in tissue is useful
fungal infection