Anisocoria increase in bright light, can be due to
(C) both sympathetic and parasympathetic lesions# Anisocoria or a difference in pupil size, is a common condition. A variety of potential causes for anisocoria exist, ranging from trivial or normal variation to life threatening.> Pathophysiology: Anisocoria may result from any of several pathophysiologies; however, it is useful to keep in mind the basic anatomy when evaluating such patients. The iris, parasympathetic pupillary constrictors, and sympathetic pupillary dilators comprise the basic pupil control system.> Causes: Homer syndrome results from sympathetic dysfunction of the eye, producing the classic combination of miosis, anhydrosis (depending on lesion location) & ptosis. Causes vary from benign to life threatening & pathophysiology often predicts the presentation> Oculomotor nerve palsy (third nerve, CN III) may affect the pupil and ocular motility. The pupil in CN III palsy appears larger and poorly reactive compared to its fellow pupil, and anisocoria is most apparent in light.> Tonic pupil: An Adie pupil is the prototype tonic pupil. Classically, the affected pupil is larger than the fellow eye, and it is poorly reactive to light.
Sympathetic lesion
Parasympathetic lesion
Both sympathetic and parasympathetic lesions
None of the above
Miscellaneous