Treatment with herceptin in breast cancer is indicated for
Treatment with herceptin in breast cancer is indicated for Tumours with over-expressed C-erb B-2 protein it is a inhibitor of C-erb B-2 protein, which is a growth factor receptor also known as Transtuzumab it is currently approved by FDA for use only in metastatic disease ref ;(page no;551) 5th edition of SRB&;S Manual of SURGERY
ER receptor +ve tumours
PR receptor +ve tumours
K : 67 stain +ve tumours
Tumours with over-expressed C-erb B-2 protein
Endocrinology and breast