A 33-year-old man is complaining of feeling thirsty all the time and passing more urine than usual. His physical examination is normal, except for a JVP at the sternal angle. His serum sodium is 150 mEq/L, glucose 120 mg/dL, and osmolality 315 mOsm/kg. The urine sodium is 20 mE/L and osmolality 260 mOsm/kg. Which of the following drugs is most likely to cause this disorder?
Nephrogenic diabetes insipidus can be caused by drugs such as lithium, metabolic factors, vascular disease, ureteral obstruction, and genetic factors.
lithium
cyclophosphamide
barbiturates
nicotine
Endocrinology