Which of the following condition is associated with the detection of clue cells on microscopy?
Clue cells are squamous epithelial cells with a fine granular epithelium and has indistinct border due to coccobacilli. They are the most reliable indicator of bacterial vaginosis. Clue cells are seen in more than 95% of patients with bacterial vaginosis. Amsel criteria for diagnosis of bacterial vaginosis: Presence of objective signs of increased white homogeneous vaginal discharge Vaginal discharge with pH of >4.5 Liberation of a distinct fishy odor due to trimethylamine, immediately after vaginal secretions are mixed with a 10% solution of KOH Microscopic demonstration of clue cells. Ref: Marrazzo J.M., Holmes K.K. (2012). Chapter 130. Sexually Transmitted Infections: Overview and Clinical Approach. In D.L. Longo, A.S. Fauci, D.L. Kasper, S.L. Hauser, J.L. Jameson, J. Loscalzo (Eds), Harrison's Principles of Internal Medicine, 18e.
Candidial vaginosis
Bacterial vaginosis
Trichomoniasis
Chlamydial infection