A 60-year-old man with no significant past medical history is scheduled for elective cholecystectomy. He has been taking aspirin daily. Preoperative recommendations should include which of the following?
Discontinuation of aspirin at least 1 week before surgery. Aspirin inactivates platelet cyclo-oxygenase and thus inhibits platelet aggregation. The effect of aspirin is irreversible and lasts for the entire life span of the platelets. Therefore, aspirin should be discontinued for at least 1 week before surgery.
Determination of prothrombin time (PT)
Estimation of platelet count
Discontinuation of aspirin 2 days before surgery
Discontinuation of aspirin at least 1 week before surgery
Miscellaneous