DOC in Wilson disease with Neurologic/Psychiatric manifestation is:
Wilson disease treatment: Condition DOC Hepatitis or cirrhosis without decompensation: Zinc Cirrhosis with decompensation: Trientine and Zinc Mild - Trientine and Zinc Moderate - Hepatic transplantation Severe - Hepatic transplantation ALSO NOTE: In patients with neurologic and psychiatric illness due to wilson the initial treatment of choice is Tetrathiomolybdatec and zinc Ref: Harrison, E-18, P-3190.
Trientine and Zinc
Zinc alone
Tetrathiomolybdate and zinc
d-Penicillamine alone