During unwinding of DNA, relief of supercoil is made possible by
During unwinding of DNA, relief of supercoil is made possible by Topoisomerase DNA helicase unwinds the DNA without cutting but using energy from hydrolysis of ATP. Gyrase is a bacterial type II topoisomerase which acts on closed circular DNA (bacteria have circular DNA).
Topoisomerase
Gyrase
Helicase
Polymerase
Replication