In a case of vesicular mole, all of following are high risk factors for the development of choriocarcinoma, EXCEPT:
High risk factors which indicates the development of choriocarcinoma at the time of diagnosis of a hydatidiform mole are: Maternal age more than 40 years Excessive uterine enlargement Serum hCG levels more than 100,000mIU/ml Theca lutein cysts greater than 6 cm in diameter Toxemia, hypehyroidism and coagulopathy Trophoblastic embolization Previously treated choriocarcinoma Ref: A Practical Approach to Gynecologic Oncology By Basu page 142.
Serum HCG levels>1,00,000 mIu/ml
Uterus size larger than 16 week
Features of thyrotoxicosis
Presence of bilateral theca lutein cysts of ovary