The level of circula ng 1,25- dihydroxycholecalciferol is significantly reduced in patients with chronic liver disease because
A healthy liver conves vitamin D (cholecalciferol) to form 25-hydroxycholecalciferol, but a diseased liver has a reduced capacity to do so. The kidney, not the liver, is responsible for the conversion of 25 hydroxycholecalciferol to 1,25-dihydroxycholecalciferol. Vitamin D, not 1,25-hydroxycholecalciferol, is absorbed by the small intestine.
The liver can no longer efficiently conve 25-hydroxycholecalciferol to 1,25-dihydroxycholecalciferol
The liver can no longer efficiently conve vitamin D to cholecalciferol
The liver can no longer efficiently conve vitamin D to 25- hydroxycholecalciferol
The liver can no longer efficiently conve cholecalciferol to 1,25-dihydroxycholecalciferol
All India exam