A 50-year-old paddy farmer presented to the ER in shock. Attendants claim that he had sudden onset of fever with difficulty in breathing about 2 days ago and subsequently also developed haemoptysis. Sputum sample was collected, and Wayson staining was done. The organism isolated was indole, MR and VP positive and fermented glucose, mannitol and maltose. It also did not hydrolyse urea. Stalactite growth was seen in the ghee broth. What is the drug of choice of the above condition and which vector transmits the above What is the drug of choice of the above condition and which vector transmits the above disease: - 1. 2. 3. 4.
This is a case of pneumonic plague caused due to yersinia pestis which is transmitted by (vector 3 in the images shown above) rat flea (Xenopsylla cheopis) and its drug of choice is streptomycin. Sho incubation period, from a few hours to 2-3 days Acute onset of the symptoms Progression from segmental pneumonitis to lobar pneumonia to B/L lung involvement. X-ray chest shows B/L alveolar infiltrates Diffuse interstitial pneumonitis MICROBIOLOGY Yersinia pestis Gram-negative coccobacilli. Bipolar staining Pleomorphic on Wayson/ Wright-Giemsa staining Small, delicate, transparent colonies on nutrient agar Colourless colonies on MacConkey agar. Stalactite growth is seen in ghee broth. Biochemicals: - Indole+, catalase+, VP+, MR+, esculin+
VECTOR = 1 / DRUG OF CHOICE = Streptomycin
VECTOR = 3 / DRUG OF CHOICE = Ampicillin
VECTOR = 2 / DRUG OF CHOICE = Gentamycin
VECTOR = 3 / DRUG OF CHOICE = Streptomycin
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