Most common tumor suppressor gene involved in cancer genesis is?
Ans. is 'b' i.e., p53 * p53 is a tumor suppressor gene. p53 gene is located on chromosome 17. p53 acts as molecular policeman that prevents the propagation of genetically damage cell.* p-53 is the most common target for genetic alteration in human tumors; A little over 50% of human tumors contain mutation in this gene.Note - Amongst oncogene RAS is involved most commonly
Rb
p53
p16
p73
Neoplasia