Naltrexone is used in opioid dependene to
Prevent relapse Naltrexone is a pure opioid antagonist It is a competitive antagonist at all opioid receptors. It can be used orally, to assist in the rehabilitation of ex-opioid abusers who are fully withdrawn (otherwise it will induce an acute withdraw! syndrome). A patient who then takes an opioid, fails to experience the kick or euphoria because of the opioid antagonistic actions of the Naltrexone.
Prevent respiratory depression
Treat withdrawal symptoms
Prevent relapse
Treatment of opioid overdose