Therpeutic drug monitoring is particularly useful for which of the following drug/s?
Ans. is 'd' i.e., All the above Therapeutic drug monitoring is particularly useful in following situations:1. Drugs with low safety margin -a) Digoxinb) Anticonvulsantsc) Antiarrythmicsd) Theophyllinee) Aminoglycoside antibioticsf) Lithiumg) Tricyclic antidepressants2. If individual variations are large -> Antidepressants, Lithium3. Potentially toxic drugs used in presence of renal failure -> Aminoglycoside antibiotic vancomycin, cyclosporine4. In case of poisoning5. In case of failure of response without any apparent reason -> antimicrobials6. To check patient compliance ->> psycho-pharmacological agents.* Drugs whose response is easily measurable eg. hypoglycaemics (metformin), antihypertensive, diuretics, oral anticoagulants and general anaesthetics, monitoring of plasma cone, is of no value.
Lithium
Aminoglycoside antibiotics
Anticonvulsants
All the above
General Pharmacology