Amino acid which is usehil in Neutrophil extracellular traps (NETs) as to causes lysis of chromatin is?
Ans. (a) Arginine(Ref: R 9th/pg 81)NETs contain a framework of nuclear chromatin with embedded granule proteins, such as antimicrobial peptides and enzymes. The nuclear chromatin in the NETs, includes histones and associated DNA. Histone modification by peptidylarginine deiminase 4 (PAD4) is necessary for NET release.
Arginine
Alanine
Phenyl alanine
Valine
Inflammation & Repair