Which of the following is the least common cause of ambiguous genitalia in a female child-
Ans is 'a' i.e., Fetal placental steroid sulfatase deficiency o Placental steroid sufatase deficiency is an X-linked disorder (affects only males) that does not lead to ambiguous genitalia in a female child. o 'Placental steroid sullatase deficiency is a rare X-linked disorder and all affected fetuses are males' William's 22'd/8I o Congenital adrenal hyperplasia is the most common cause of ambiguous genitalia in female child. o Fetal placental aromatase deficiency and WNT-4 gene mutation cause ambiguous genitalia in female child.
Fetal placental steroid sulfatase deficiency
Fetal placental aromatase deficiency
Congenital adrenal hyperplasia
WNT-4 gene mutation