A 25 year old male presnents with weakness, occasional vomiting hypotension, skin and mucous membrane pigmentgation. The diagnosis can be best established by -
after administration of ACTH , coisol level increases. This can be used as an index of the functional reserve of adrenal gland for production of coisol ( Harrison 17 pg 2252)
Metyrapone test
Basal plasma Coisol levle
24-hour urinary 17-Ketosteroid
ACTH stimulation test
Endocrinology