Causative factor acne are following except:
Acne is a chronic inflammatory disease of the pilosebaceous units, skin structures consisting of a hair follicle and its associated sebaceous gland Major factors are involved in the pathogenesis: - Hormonal factors (| androgens, Insulin resistance, Insulin growth factor-1(IGF-1) - | IL-1a activity - | Lenoleic acid - Increased sebum production k/a Seborrhea, - Hypercornification of the pilosebaceous duct, - Abnormality of the microbial flora especially colonization of the duct with Cutibacterium acnes. - The activity of bacteria (C.acnes) within the comedones releases free fatty acids from sebum, causes inflammation within the cyst, and results in rupture of the cyst.
Androgen
Oily food
Bacterial proliferation
Hypercornification of duct
Acne and chemical peeling