After staing your patient on imipramine, his hea rate rises to 120/min and he has blurred vision. These effects can be explained by the fact imipramine:
(Ref: KDT 6/e p444) These symptoms are of anticholinergic drugs. Tricyclic antidepressants have powerful anticholinergic propeies and can lead to these symptoms.
Is a muscarinic antagonist
Potentiates epinephrine
Is a ganglionic blocker
Is a potent a-adrenergic blocker
Other topics and Adverse effects