Best method to diagnose typhoid in the first week is ?
Blood, intestinal secretions (vomitus or duodenal aspirate), and stool culture results are positive for S typhi in approximately 85%-90% of patients with typhoid fever who present within the first week of onset. They decline to 20%-30% later in the disease course Ref Harrison20th edition pg 1079
Blood cultrue
Bone marrow cultrue
Urine culture
Stool culture
Infection