Most common mutation in haemophilia is:
Genetic abnormalities in haemophilia : Inversions: Intron 22 inversion, Intron 1 inversion Point mutations: Missense mutation, nonsense mutation, frameshift mutation Deletion of pa or whole of gene Inseion of repetitive sequences Splicing errors affecting production of mRNA Hemophilia A(factor 8 deficiency) -x linked recessive trait, affects mainly males and homozygous females Hemophilia B - x linked disorder caused by mutations in coagulation Factor 9
Intron 1 inversion
Intron 22
619 bp deletion
3.7 bp deletion
Blood disorder