Miss folded proteins might be produced due to defect of:
Rough endoplasmic reticulum is associated with protein synthesis, protein folding and miss folded protein degradation. Ref:Guyton and Hall textbook of medical physiology 12th edition,page number:10,11,12
Cholesterol
Mitochondrial
Rough endoplasmic reticulum
Smooth endoplasmic reticulum
General anatomy