<img alt="" src=" />MIC-2 is a marker of
Study repos on the specific expression of the MIC2 gene, a pseudoautosomal gene located on the sho arms of the X and Y chromosomes, on Ewing&;s sarcoma (ES) and peripheral primitive neuroectodermal tumor (pPNET) cells. The gene product, a cell membrane protein, is recognized by the newly established monoclonal antibody (MoAb) HBA-71 and the previously described MoAb 12E7 and RFB-1. Fuhermore, the reaction pattern of the MIC2 antibodies, especially HBA-71, with normal tissues and a great number of benign and malignant tumors (70 different tumors, 199 tumor samples), as well as the correlation between the specific chromosomal aberrations.
Ewing's sarcoma
Osteosarcoma
Dermatofibrous protruberns
Alveolar cell sarcoma
Breast