A common intermediate in the conversion of glycerol and lactate to glucose is which one of the following?
The only intermediate included in the list that the pathway of gluconeogenesis from glycerol has in common with the pathway of gluconeogenesis from lactate is glucose-6-phosphate. Glycerol enters gluconeogenesis as DHAP. Therefore, it bypasses the other compounds (pyruvate, oxaloacetate, malate, and PEP) through which the carbons of lactate must pass on its pathway to glucose synthesis.
Pyruvate
Oxaloacetate
Malate
Glucose-6-phosphate
Carbohydrates