Which of the following statements about Atherosclerosis is true:
Answer is A (Intake of Unsaturated Fatty Acids is associated with decreased risk) The maximal benefit is observed with Omega 3 Poly-unsaturated Fatty Acids, however Mono-unsaturated Fatty Acids also have consistent anti-atherosclerotic benefits and both Poly-unsaturated Fatty Acids (PUFA) and Monounsaturated Fatty Acids (MUFA) are considered Cardioprotective Fatty Acids. Hypercholestoremia alone may increase the risk of Atherosclerosis `Hyperlipidemia and more specifically hypercholesterolemia is a major risk factor lb,. atherosclerosis. Even in the absence of other factors, hypercholesterolemia is sufficient to stimulate lesion development'. - Robbins 8th/497 Extent of Athrosclerosis is more severe in aeries than in veins Atherosclerosis is always severe in areas where pressure and velocity are high (as in aeries) in contrast to areas where pressure and velocity are low (as in veins). 'Overall atherosclerosis is more severe in high-pressure aeries than in pulmonary aeries with lower blood pressure. It is least severe in veins where pressure and velocity are lowest' - 'Pan - Vascular Medicine' by Topol (2002)/90 Abdominal Aoa is more commonly involved than Thoracic Aoa `Abdominal Aoa is more commonly involved than Thoracic Aoa. Within the abdominal aoa lesions tend to be more prominent around the ostia' - `Med Essentials' (Kaplan Publishing) 2007/249 `In the systemic circulation severity is accentuated in the abdominal aoa and large aeries of the lower limb where pulse wave reflection and summation effect elevate the pulse and systolic pressures. The disease is more severe in large rather than small vessels indicating the impoance of mural tension and Reynolds number both of which are propoional to radius increasing the likelihood and severity of effects of blood flow disturbance at aerial forks, junctions and curvatures'.- 'Pan Vascular Medicine'
Intake of Unsaturated Fatty Acids is associated with decreased risk
Extent of lesions in veins is similar as that in aeries
Thoracic Aoa is more commonly involved than abdominal aoa
Hypercholesterolemia alone does not increase the risk of atherosclerosis per se