Patient with HNPCC (hereditary nonpolyposis colon cancer) has genes with microsatellite instability. This is due to failure of which repair mechanism of DNA
Mismatch repair: It is one of the repair mechanisms in DNA replication. It operates when there is mismatched base paining. For eg: when A pairs with C. This repair mechanism is defective in HNPCC.
Mismatch repair
Base excision repair
Homologous end joining repair
Non homologous end joining repair