A patient of depression is getting chlorpromazine, but his auditory hallucination are not controlled. The next drug is given
B i.e. Clozapine Clozapine is an antipsychotic drug with least extrapyramidal side effectsQ, i.e. it has least chances of producing muscular dystonia, akathisia, malignant neuroleptic syndrome, & tardive dyskinesiaQ. The patient who has depression & auditory hallucinations & is being treated with CPZ i.e. the patient is a case of schizophrenia. The patient is a case of resistant schizophrenia as the auditory hallucinations are not responding to treatment. As you must know - Auditory hallucinations are first symptom to go with treatment & also 1st symptom to reappear after drug resistanceQ.
Haloperidol
Clozapine
Suipride
Tianeptin