Syncytium formation is the typical CPE produced by:-
Syncytium formation is the typical CPE produced by Measles Virus. 1. Cytopathic effect (CPE): It is defined as the morphological change produced by the virus in the cell line detected by light microscope. 2. Types of Cytopathic Effects (CPE): Rapid crenation and degeneration of the entire cell sheet - Enteroviruses. Syncytium or multinucleated giant cell formation - Measles, RSV, HSV. Diffuse roundening and ballooning of the cell line - HSV. Cytoplasmic vacuolations - SV 40 (Simian vacuolating virus-40). Large granular clumps resembling bunches of grapes - Adenovirus. 3. Syncytia is formed by fusion of an infected cells with neighboring cells leading to the formation of multi-nucleated enlarged cells. This event is induced by surface expression of viral fusion protein that are fusogenic directly at the host cell membrane.
BK virus
JC virus
SV 40 virus
Measles virus
Virology (General Propeies, DNA Viruses)