'Hand and Foot' syndrome can be caused by:
CAPECITABINE is a PYRAMIDINE ANTAGONIST. It is an orally active prodrug of 5-FU.A combined regimen of capecitabine and oxaliplatin is frequently used in metastatic colorectal cancer. HAND-FOOT syndrome and diarrhoea are the prominent adverse effects,but bone marrow depression and mucositis are less marked. ESSENTIALS OF MEDICAL PHARMACOLOGY K.D.TRIPATHI SEVENTH EDITION PAGE NO:864
Cisplatin
Vincristine
Capecitabine
Mitomycin-C
Chemotherapy