Oxidative or Respiratory burst phenomenon?
Activation of NADPH oxidase is associated with a sharp increase in O2 uptake and metabolism in the neutrophil (the respiratory burst) and generation of O2- by the following reaction: NADPH + H++ 2O2+ - NADP++ 2H++ 2O2- Reference: Ganong's Review of Medical Physiology; 25th edition; Page no: 68
Due to antimicrobial proteins called defensins
Occurs during diapedesis
Activation of NADPH oxidase associated with increase in oxygen uptake and metabolism in neutrophils
Production of HOCl, HOBr from Cl-, Br- respectively by the action of myeloperoxidase
General physiology