Cachectin is produced by-
Cachectin (Tumour necrosis factor - α) is produced by -

Macrophages
Monocytes
N.K. Cells

Biological effects of TNF-α

Tumor cytotoxicity
Induction of acute phase proteins
Lipolysis
Endotoxic shock
Fever
Antiviral and antiparasitic effect
Cachexia
Phagocytic cell activation
Neutrophils
Eosinophils
Macrophages
Basophils