Drug of choice in lithium induced polyuria is?
Amiloride REF: Goodman & Gillman's 11th edition page 494, 505 "Lithium-induced polyuria is usually reversible. Amiloride is useful for lithium-induced nephrogenic diabetes insipidus because it blocks Li+ transpo into the cells of the collecting tubules" "Paradoxically, thiazide diuretics reduce the polyuria of patients with DI and often are used to treat non-lithium-induced nephrogenic DI" "While case repos describe the effectiveness of indomethacin in the treatment of nephrogenic DI, other cyclooxygenase inhibitors (e.g., ibuprofen) appear to be less effective"
Amiloride
Demeclocycline
Thiazide diuretics
Indomethacin