Which of the following conditions is associated with Coomb's positive hemolytic anaemia:
Answer is C (systemic lupus erythematosis) Coomb's positive hemolytic anemia is a feature of autoimmune vascular disease and may also be seen in SLE and other Collagen Vascular diseases including PAN and Systemic sclerosis. However amongst the options provided coombs positive hemolytic anemia is most commonly associated with SLE which is the single best answer of exclusion. Autoimmune hemoletic anemias are associated with 'collagen vascular diseases especially systemic lupus Erythematosis'- Harrisons Autoimmune hemolytic anemia are associated with 'autoimmune diseases paicularly Systemic Lupus Erythematosis' -Hoffman.
Thrombotic thrombocytopenic purpura
Progressive systemic sclerosis
Systemic lupus erythematosus
Polyaeritis nodosa