Principal Actions of prostacyclin in Inflammation is
Principal Actions of Arachidonic Acid Metabolites in InflammationActionEicosanoidVasodilationProstaglandins PGI2 (prostacyclin), PGE1, PGE2, PGD2VasoconstrictionThromboxane A2, leukotrienes C4, D4, E4Increased vascular permeabilityLeukotrienes C4, D4, E4Chemotaxis, leukocyte adhesionLeukotrienes B4, HETERef: Robbins and Cotran Pathologic Basis of Disease; 9th edition; Chapter 3; Inflammation and Repair; Page no: 84; Table 3-5
Vasodilation
Vasoconstriction
Increased vascular permeability
Chemotaxis, leukocyte adhesion
General pathology