Mucositis is caused by:
Flurouracil is used mainly for solid malignancies,i.e colon, rectum, pancreas, liver, urinary bladder, head, and neck. Genetic deficiency of dihydropyridine dehydrogenase(DPD) leads to Fluorouracil toxicity. Major toxicity is myelosuppression, mucositis, diarrhea, nausea, vomiting, peripheral neuropathy (hand-foot syndrome)also occurs. Other given drugs are anti-cancerous drugs without mucositis. ESSENTIALS OF MEDICAL PHARMACOLOGY-SEVENTH EDITION-K.D TRIPATHI Page; 864
5-Fluorouracil
Methotrexate
Paclitaxel
Cisplatin
Other topics and Adverse effects