Which of the following drugs has covalent interaction with its target
Aspirin is Acetylsalicylic acid conves to salicylic acid in the body, responsible for the action. It acts irreversibly by binding to cox enzyme through covalent- strong bonds ESSENTIALS OF MEDICAL PHARMACOLOGY;7TH EDITION; KD TRIPATHI;PAGE NO 195
Aspirin
Penicillin
Nitric oxide
Bosentan
Autacoids