True statement about clonidine are all except-
Ans-D Clonidine is an alpha-2 agonist that acts by decreasing the central sympathetic outflow.Sedation, dry mouth and rebound hypertension are the principal adverse effects associated with clonidine. Prazosin is an a1 selective blocker, therefore it is not able to block alpha-2 mediated actions.
Increases parasympathetic outflow
Decreases sympathetic outflow by blocking central alpha receptor
Used in Hypertension
Prazosin is used to antagonize side effects of clonidine