Which drugs action needs insulin presence to produce its therapeutic action?
Metformin and glitazones require insulin for their action as they are just insulin sensitizers not releasers. They sensitize the tissue to insulin hence require insulin for their action. Ref: KD Tripathi 8th ed.
Glibenclamide
Nateglinide
Pioglitazone
Empagliflozin
Endocrinology