A small amount of atropine is added to diphenoxylate in order to:
Atropine is intentionally added to diphenoxylate in fixed dose combinations to intentionally produce the adverse effects. - If the person takes diphenoxylate in large doses to get the euphoria, atropine will produce adverse effects and the person will not abuse the drug.
Suppress associated vomiting of gastroenteritis
Augment the anti-motility action of diphenoxylate
Block side effects of diphenoxylate
Discourage overdose and abuse of diphenoxylate
Gastro-Intestinal Tract