Caseous granuloma is seen in
ref Robbins 8/e p718 from tuberculous lesions often contain caseous , , other , and contain epithelioid cells, a few lymphocytes, and occasional multinucleated giant cells. No necrosis is seen. Granulomas following are noncaseous and characterized by epithelioid cell reaction with giant cells and , and the is based on finding organisms or and mononuclear macrophages when examined under polarized light. The crystals are composed of hydrous Fungal infections Most Histoplasma capsulatum. The granulomas are often isolated or small and scattered, thereby resembling miliary granulomas. The organism can be identified histologically. They are intracellular organisms, with 1-5 mm, round to oval yeast-like bodies, with a small, central round nucleus. Periodic acid-Schiff (PAS) and methenamine-silver (Meth-Ag) stains highlight these organisms. Other fungi that may cause granulomas are Cryptococcus neoformans (Fig. 21.4A), Blastomyces Fig. 21.4B), Mucorales, causing Fig. 21.4C), and Coccidioides immitis.13Some of these organisms are associated with definite geographical regions. Because of the ease of travel, however, diseases do not necessarily present in a Fungal infections Most Histoplasma capsulatum. The granulomas are often isolated or small and scattered, thereby resembling miliary granulomas. The organism can be identified histologically. They are intracellular organisms, with 1-5 mm, round to oval yeast-like bodies, with a small, central round nucleus. Periodic acid-Schiff (PAS) and methenamine-silver (Meth-Ag) stains highlight these organisms. Other fungi that may cause granulomas are Cryptococcus neoformans (Fig. 21.4A), Blastomyces (Fig. 21.4B), Mucorales, causing Fig. 21.4C), and Coccidioides immitis.13Some of these organisms are associated with definite geographical regions. Because of the ease of travel, however, diseases do not necessarily present in a <a style="box-sizing: border-box; margin: 0px; padding: 0px; background-color: transparent; overflow-x: auto; color: ; transition: color 0.3s ease 0s, border-bottom-color 0.3s ease 0s; text-decoration-line: none;" title="Learn more about Geographic Distribution from ScienceDirect's AI-generated Topic Pages" href=" distribution</a>
Histoplasmosis
Silicosis
Sarcoidosis
Foreign body
General anatomy