A patient with autoimmune thyroditis present with hypothyroidism. Which of the following is true
The major cause of hypothyroidism in adults is Hashimoto thyroiditis, autoimmune-mediated destruction of thyrocytes. The disorder predominates in women Presence of TSH-blocking antibodies, such as thyroid peroxidase antibodies, can be detected The onset, thyroid status and the type of goitre vary profoundly from case to case. The onset may be insidious and asymptomatic, or so sudden and painful that it resembles the acute form of granulomatous thyroiditis. Papillary carcinoma and malignant lymphoma are occasionally associated with autoimmune thyroiditis Source Sabiston 20 th edition Pg : 891 Bailey and Love Pg : 770
Thyroid peroxidase antibodies
Painless enlargement of thyroid
Common in men
No malignant risk
Endocrinology and breast