Gene for folate carrier protein is located on chromosome
Folate cofactors are one-carbon donors essential for the biosynthesis of purines and thymidylate. Mammalian cells are devoidof folate biosynthesis and are therefore folate auxotrophs that take up folate vitamins primarily via the reduced folate carrier (RFC). The gene for RFC is located on chromosome 21.
Chromosome 21
Chromosome 5
Chromosome 10
Chromosome 9