OCP's are contraindicated in women receiving which of the following drug ?
OCPs are contraindicated in patient on enzyme-inducing drugs like rifampicin, and antiepileptic except sodium valproate. Rifampicin induces cytochrome 450 ,increasing the hepatic hydroxlation of estrogen by which there is a fourfold increase in its metabolism. This causes clearance and deceased effect of estrogen. Reference: Shaw's textbook of Gynaecology 17th edition,page 265.
Rifampicin
Ethambutol
Streptomycin
Pyrazinamide
Contraception