Which is true about type II hypersensitivity reaction?
Type II or Cytotoxic Hypersensitivity depends on the abnormal production of IgG or IgM directed against tissue antigens or a normal reaction to foreign antigens expressed on host cells. There are three main mechanisms of injury in Type II reactions:* Activation of complement followed by complement mediated lysis or phagocytosis and removal by leukocytes* Antibody dependent cellular cytotoxicity* Inactivation of a biologically active molecule
Immune complex mediated
Antigen - antibody mediated
Arthus phenomenon
Granulomatous reaction
Immunity