A female presents with history of progressive breathlessness. Histology shows heterogenous patchy fibrosis with several fibroblastic foci. The most likely diagnosis is:
Histologic hallmark of UIP is a heterogeneous appearance at low magnification with alternating areas of normal lung, interstitial inflammation, foci of proliferating fibroblasts, dense collagen fibrosis and honeycomb changes. Ref: Harrison's Principles of Internal Medicine, 16th Edition, Page 1557.
Cryptogenic Organizing Pneumonia
Non Specific Interstitial pneumonia
Usual Interstitial Pneumonia
Desquamative Interstitial Pneumonia