Mechanism of resistance of tetracyclines is due to?
Mechanism of Resistance Examples Enzymatic breakdown A: Aminoglycosides B: Beta lactams C: Chloramphenicol Decreased permeability Aminoglycosides Efflux pumps Tetracyclines Altered metabolic pathway Sulfonamides Altered target MRSA Vancomycin, Fluoroquinolones
Drug efflux mechanism
Development of inactivating enzymes
DNA methylation
Cell wall alteration
JIPMER 2019