Integrin connects actin to which macromolecule in ECM?
Ans. C. Fibronectin > LamininIntegrins localized in the plasma membrane are the major adhesion receptor connecting cells with components of the extracellular matrix. Integrins interact directly with laminin and mainly fibronectin present in the basal lamina and intracellularly contact actin through intermediate proteins, such as alpha-actinin, vinculin, and talin. Integrins are calcium-independent adhesion molecules.
Vitronectin
Laminin
Fibronectin
Collagen
Inflammation & Repair