A 40-year-old female presented to B/L parotid gland enlargement with complaints of dry eyes, dry mouth, chronic non-productive cough and shoness of breath. On examination, hepatosplenomegaly was noted. CT scan of chest Ceain tests were conducted. A biopsy from the affected salivary gland was also taken. Which of the following interleukins is involved in the pathogenesis of the above disease: -
This is a case of Sjogren's syndrome. 1st image shows picture of ILD (honeycombing). 2nd image shows the Schirmer's test being conducted. 3rd image shows the lymphocytic infiltrate - suggestive of Sjogren syndrome. Presents with a triad of: - Dry eyes Dry mouth B/L parotid enlargement Also, there is Hepatosplenomegaly ILD Vasculitis Anemia of chronic disease Pathogenesis Presence of IL-18 positive macrophages Predominance of T-cells. Low levels of C4 complement.
IL-17
IL-18
IL-15
IL-10
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