Decrease in contributing factor in chronic hypeension is associated with
Twofold increase in plasma TNF-alpha levels in pregnant rats resulted in a significant increase in aerial pressure (97 +/- 3.6 v 116 +/- 2.1 mm Hg, pregnant versus TNF-alpha pregnant, respectively, P < .05), but no significant change in urinary nitrite/nitrate excretion (22.0 +/- 1.9 v 20.8 +/- 2.5 micromol/24 h, pregnant versus TNF-alpha pregnant, respectively), a measure of whole-body NO production.
Aldosterone
Angiotensin II
Nitric oxide
Reduced sympathetic nerve
Cardiovascular system