True about methicillin-resistant Staphylococcus aureus (MRSA) is
Penicillin resistance may also be due to alterations in penicillin-binding protein PBP2a and changes in bacterial surface receptors, reducing binding of beta-lactam antibiotics to cells. This resistance also extend to cover beta lactamase resistant penicillin such as methicillin and cloxacillin(MRSA)
Some of these strains may show resistance to other antibiotics like erythromycin, tetracyclines, aminoglycosides and heavy metals.
Isoxazolyl penicillin is highly effective
All MRSA are multidrug resistance
Vancomycin is effective
MRSA are more virulent than sensitive strains