Hypervitaminosis of which of the following will cause bony abnormalities?
HYPERVITAMINOSIS A: Chronic hypervitaminosis A results from excessive ingestion of preformed vitamin A (retinol or retinyl ester), generally for several weeks or months. Toxicity can be induced in adults and children with chronic daily intakes of 15,000 mg and 6,000 mg, respectively. Signs of subacute or chronic toxicity can include a headache; vomiting; anorexia; dry, itchy desquamating skin; seborrheic cutaneous lesions; fissuring at the corners of the mouth; alopecia and/or coarsening of the hair; bone abnormalities; swelling of the bones; enlargement of the liver and spleen; diplopia; increased intracranial pressure; irritability; stupor; limited motion; and dryness of the mucous membranes; desquamation of the palms and the soles of the feet. Radiographs may show hyperostosis affecting several long bones, especially in the middle of the shafts. As there is no antidote for hypervitaminosis A, the prevention of this condition is most impoant. Ref: Nelson textbook of pediatrics; 20th edition; Chapter 48 Vitamin A Deficiencies and Excess
Vit A
Vit D
Vit C
Vit E
Nutrition