Causes of Type 2 renal tubular acidosis are all except:
Ref: Nelson's Textbook of Pediatrics 18th edition: page no.2197Explanation:Renal tubular acidosis (RTA)It is a disease state characterized by a normal anion gap metabolic acidosis resulting from either impaired bicarbonate reabsorption or impaired urinary acid (hydrogen ion) excretion.There are 3 main forms of RTA:Proximal (type II) RTADistal (type I) RTA. andHyperkalemic (type IV) RTA.Mixed lesions (those with elements of type I and II RTA), which occur primarily in patients with inherited carbonic anhydrase deficiency, are designated as type III RTA by some authors. Causes of HvponatremiaHYPOVOLEMICHYPONATREMIAEUVOLEMC HYPONATREMIAHYPERVOLEMICHYPONATREMIAExtrarenal losses* Gastrointestinal (emesis, darrhea)* Skin (sweating or bums)* Third space losses* SIADH* Glucocorticoid deficiency* Hypothyroidism* Water intoxication* CHF* Orthosis* Nephrotic syndrome* Renal failure* Capillary leak due to sepsis* Hypoaibuminemia due to gastrointestinal disease (protein-losing enteropathy)Renal losses* Thiazide or loop diuretics* Juvenile nepbronophthisis* Tubulointerstitial nephritis* Obstructive uropathy* Cerebral salt wasting* Proximal (type II) renal tubular acidosis* Lack of aldosterone effect (high serum potassium)Proximal RTA usually occurs as a component of global proximal tubular dysfunction or Fanconi syndrome, which is characterized by low molecular weight proteinuria, glycosuria, phosphaturia, aminoaciduria, and proximal RTA (See the following table)
Cystinosis
Lowe syndrome
Essential fructosuria
Gaiatosemia
Renal Tubular Disease