Which is not a feature of Kallman syndrome?
Kallman Syndrome occurs due to defective synthesis of GnRH (Gonadotropin releasing hormone). KAL gene is X linked. During fetal life, the GnRH neurons originate in Olfactory Placode and then migrate along fetal olfactory neuron. They eventually wend their way to the hypothalamus. Presenting features Associated with Males: delayed pubey and micro-penis. Females: Primary amenorrhea and failure of development of secondary sexual characteristics Anosmia Colour blindness, optic atrophy SN deafness Mirror movements of hands (synkinesia) Cleft palate Renal abnormalities Mirror movements
Micropenis
Primary amenorrhea
Mirror movements of hands
Mental retardation
Disorders of pituitary gland