Niemann-Pick disease occurs due to a defect in
DiseaseEnzyme DeficiencyClinical SymptomsNiemann-Pick diseaseSphingomyelinaseEnlarged liver and spleen, mental retardation;fatal in early lifeRef: Harper&;s Biochemistry; 30th edition; Chapter 24 Metabolism of Acylglycerols & Sphingolipids
Ceramidase
Sphinogomyelinase
Phospholipase C
b - galactosidase
Metabolism of lipid