An elderly woman underwent a radical mastectomy with radiation to the axilla 20 years ago. For 25 years, she has had an open wound that has never healed. It is not a recurrence of breast cancer. It is most likely:
First described by Marjolin in 1828 and known as Marjolin's ulcers, malignant degeneration arising in a chronic wound is nearly always squamous cell carcinoma. These lesions are most commonly seen in burn scars but have been associated with osteomyelitis, radiation therapy, hidradenitis suppurativa, and diabetic ulcers.
Basal cell carcinoma
Squamous cell carcinoma
Hypertrophic granulation tissue
Malignant melanoma
Miscellaneous