Which of the following drugs should not be administered concomitantly with warfarin as it decreases the effect of oral anticoagulants
Oral contraceptives Estrogen increases the synthesis of various clotting factors and produce a hypercoagulable state. Thus OCP containing estrogen decrease the effectiveness of warfarin and other oral anticoagulants.
Broad spectrum antibiotic
Cimetidine
Aspirin
Oral contraceptive