Defect in phenylketonuria
In this condition phenylalanine can&;t be conveed to tyrosine, so phenylalanine accumulates and it&;s level in blood is elevated.Ref: DM Vasudevan - Textbook of Biochemistry, 7th edition, page no: 236, fig 18.1
Phenylanine hydroxylase
Homogentisate oxidase
Pyruvate hydroxylase
Fumarylacetoacetate hydroxylase
Metabolism of protein and amino acid