Most sensitive investigation for preoperative localization of abnormal parathyroid glands is:
Neck ultrasound locates glands in approximately 75% of cases. (99mTc) labeled Sestamibi isotope scans identify approximately 80% of abnormal parathyroid glands.
CT & MRI is not indicated prior to first time neck exploration.
Neck ultrasound
(99mTc) labelled Sestamibi isotope scan
CT scan
MRI