A 30 year old male was dignosed with Hodgkin's lymphoma and was staed on Bleomycin . Which of the following is false regarding Bleomycin?
Most Anticancer drugs cause bone marrow suppression. However, these drugs are marrow sparing: Vincristine Bleomycin Asparaginase Bleomycin is metabolized by bleomycin hydrolase. Later is deficient in skin and lungs. Therefore these organs are at high risk of toxicity (flagellated skin pigmentation and pulmonary fibrosis)
It can cause pulmonary fibrosis
It can cause flagellated pigmentation of skin
It is metabolized by hydrolase enzyme
It has high risk of causing bone marrow suppression
Cytotoxic Anticancer Drugs