With respect to ticlopidine, clopidogrei:
(Ref: KDT 6/e p610) Ticlopidine and clopidogrel are ADP antagonists and are used as antiplatelet drugs. Antiplatelet action, chances of bleeding and formation of antibodies is similar with these two agents. Clopidogrel is better tolerated because it is less likely to cause severe neutropenia and thrombocy topenia as compared to ticlopidine.
Is more likely to cause formation of antiplatelet antibodies
15 less likely to cause neutropenia
Is more likely to cause severe bleeding
Has a greater antiplatelet effect
Other topics and Adverse effects