Which of the following drug used in gout act by conveing uric acid into allantoin ?
Ans: D. RasburicaseDrugs increasing metabolism of uric acid:Urate oxidase metabolizes insoluble uric acid to soluble allantoin in the birds'.This enzyme is absent in humans.Rasburicase (a recombinant urate oxidase) is used for this Purpose.PEGylateil uricase (pegloticase) is another similar drug.
Colchicine
Allopurinol
Probenacid
Rasburicase