Why carpopedal spasm seen in hyperventilation:
Hyperventilation | Alkalosis | increase in plasma protein binding to Ca++ | Overall decrease in serum Ca++ | Carpopedal spasm. At plasma calcium ion concentrations about 50 percent below normal, the peripheral nerve fibers become so excitable that they begin to discharge spontaneously, initiating trains of nerve impulses that pass to the peripheral skeletal muscles to elicit tetanic muscle
Increased sequestration of Ca in SER
Increased plasma protein binding of Ca
Ca utilized in bones
Increased excretion of calcium in urine
Cell Membrane and transpo protiens