Relative to filgrastim (G-CSF), sargramostim (GM-CSF)
Stimulates production of a wider variety of hematopoietic stem cells GM-CSF has wider biologic activity than G-CSF; it stimulates early myeloid stem cells in addition to cells destined become neutrophils.
Has greater oral bioavailability
Is more likely to cause thrombocytopenia
Is more likely to elicit an allergic reaction
Stimulates production of a wider variety of hematopoietic stem cells