Naltrexone is used in opioid dependence to -
Naltrexone is a pure opioid antagonist. It is competitive antagonist at all opioid receptors. It can be used orally, to assist in the rehabilitation of ex-opioid abusers who are fully withdrawn (otherwise it will induce an acute withdrawal syndrome). A patient who then takes an opioid, fails to experience the kick or euphoria because of the opioid antagonistic actions of the Naltrexone.
Prevent respiratory depression
Treat withdrawal symptoms
Prevent relapse
Treatment of opioid overdose