Which of the following induction agent may cause adrenal coex suppression?
Etomidate is an induction anaesthetic which cause suppression of production of steroids from adrenals. It is therefore not suitable for continuous intravenous use. It has brief duration of action (5-10min) and produce little cardiovascular and respiratory depression. It produce prominent motor restlessness and rigidity. Use of etomidate should be restricted to clinical situations in which its hemodynamic stability offers a distinctive advantage over the other available induction drugs (e.g. elderly outpatients with clinically significant coronary aery or cerebrovascular disease). Ref: Essentials of Medical Pharmacology By K D Tripathi, 5th Edition, Pages 342-4
Propofol
Ketamine
Etomidate
Thiopentione