Cause of repeated 2nd trimester foetal loss:
Common known causes of abortion:
First trimester: defective germ plasm, hormonal deficiency, trauma, acute infection.
Mid trimester: Cervical incompetence, uterine malformations, uterine fibroid, low implantation of placenta, twins and hydramnios
Chromosomal anomaly
Intrauterine infection
Abnormality of cervix and uterus
Hormonal imbalance