All of the following are known risk factors for the development of ovarian carcinoma except :
Ans. is b i.e. Use of oral pills Oral pills decrease risk of developing ovarian carcinoma. Risk factor for ovarian cancer : Factors related to ovary Personal Factors Genetic disease PCOD Ovulation inducing drugs Exogenous estrogens Family history High dietry intake of saturated fat Nulliparity Turner syndrome - increases risk of dysgerminoma and gonadoblastoma Breast ovarian cancer syndrome - related to mutation in BRCA-1 & BRCA-2 HNPCC syndrome = Lynch II syndrome - associated with colon cancer, Facto. ....t.;;Aeasing ovarian cancer : Oral contraceptive pills (decrease risk by 50% for user of 5 years or longer) Pregnancy - (Risk reduction of 13 to 19% per pregnancy) Breast feeding - Chronic anovulation - Multiparity Tubal ligation, hysterectomy. Remember :A simple "Funda" Repeated ovulation increases the risk of ovarian cancer. So, anovulation, pregnancy, multiparity and breast feeding are protective against ovarian cancer.
Family history of ovarian carcinoma
Use of oral pills
Use of Clomiphene
BRCA - 1 positive individual