In-situ DNA nick end labeling can quantitate:
In situ DNA nick end - labeling In-situ method for detecting areas of DNA which are nicked during apoptosis. Terminal deoxynucleotidyl transferase mediated dUTP-biotin nick end labeling (TUNEL) is a method for detecting apoptotic cells that exhibit DNA fragmentation.
Fraction of cells in apoptotic pathways
Fraction of cells in S phase
p53 gene product
bcr/abl gene
Introduction