Which of the following statement is true regarding Atazanavir:-
Atazanavir is effective against both against HIV 1 and HIV 2 but NNI are effective only against HIV 1. They do not decrease cholesterol and triglyceride levels. Combination with ritonavir have an advantage due to the phenomenon of Ritonavir boosting. The resistance is due to mutation in codon 50 isoleucine to valine substitution.
Effective against only HIV-1
Resistance is due to mutation in codon 50 isoleucine to valine substitution
Decrease cholesterol and triglyceride levels
Combination with ritonavir do not have any advantage
Anti-HIV Drugs