Which of the following is an increased risk of breast cancer?
Ans is b i.e. Atypical hyperplasia A history of breast biopsy for benign breast disease have an increased risk of breast cancer. The degree of increase in risk depends on the specific epithelial abnormality. The table below shows the relative associated risks for patients with benign histologic findings. American Board of Pathology Histologic Classiflairli of Benign Disease Histopathology Approximate Relative Risk No added risk Nonproliferative Cysts Duct ectasia Calcification Fibroadenoma Milk ductal epithelial hyperplasia Sclerosing adenosis No added risk Papillomatosis Slight added risk Radial scars Complex sclerosing lesions ? Moderate or florid hyperplasia 1.5:1 to 2:1 Atypical hyperplasia (ductal and lobular) 4:1 Extensive ductal involvement of atypical hyperplasia 7:1 Lobular carcinoma in situ 10:1 Ductal carcinoma in situ 10:1
Sclerosing adenosis
Atypical hyperplasia
Fibroadenoma
Florid hyperplasia