Amiloride can cause hyperkalemia due to its action on:
Ans. B. Sodium channelAmiloride and triamterene are K+ sparing diuretic, they act by inhibiting epithelial Na+ channel. When they inhibit the sodium channel, there is no generation of electrical gradient and thus potassium and hydrogen are not excreted. They may be responsible for hyperkalemia.
Potassium channel
Sodium channel
Na+ Cl- symporter
H+K+ATP ase
Diuretic