All of the following statements about vincristine are true except
Vincristine is a vinca allkaloid. It acts in M-phase of cell cycle by inhibiting the formation of spindle. It is a marrow sparing drug and causes peripheral neuropathy as a prominent adverse effect. It is used for the treatment of hematological malignancies like Hodgkin's lymphoma and leukemias.It is ineffective against solid tumors. Ref-KDT 6/e p824,825
It acts by inhibiting mitosis
It prominent adverse effects is peripheral neuropathy
It does not suppression bone marrow
It is a drug of choice for solid tumors
Other topics and Adverse effects