Autosplenectomy is seen in?
ANSWER: (C) Sickle cell anemiaREF: Harrisons Internal Medicine 17th edition Chapter 60. Enlargement of Lymph Nodes and Spleen, CMDT 2009 chapter 13 Blood Disorders > AnemiasPatients with sickle cell disease often suffer from autosplenectomy as a result of splenic destruction by the numerous infarcts associated with sickle cell crises during childhood.Indeed, the presence of a palpable spleen in a patient with sickle cell disease after age 5 suggests a coexisting hemoglobinopathy, e.g., thalassemia or hemoglobin C
Hereditary spherocytosis
G6 PD deficiency
Sickle cell anemia
Thalassemia major
Blood