Which of the following is true about felty&;s syndrome?
Felty's syndrome defined by the clinical triad of neutropenia, splenomegaly, and nodular RA and is seen in less than 1% of patients. It typically occurs in the late stages of severe RA and is more common in whites than other racial groups. T cell large granular lymphocyte leukemia (T-LGL) may have a similar clinical presentation and often occurs in association with RA. Ref: Harrison&;s Principles of Internal Medicine; 20th edition; Chapter 380 Rheumatoid Ahritis; Page no: 2138
More common in males
Occurs in early phase of disease
RA, lymphopenia, splenomegaly
Associated with high titres of RF
Immune system