Human immunodeficiency virus (HIV) affects the immune response. The primary change brought about is:
HIV infects CD4 (helper) T-lymphocytes, macrophages and monocytes and leads to cell-mediated immune deficiency which predisposes to opportunistic infections and malignancies.
A gammaglobulinemia
Defect in cell-mediated immunity
Defect in complement system
Defect in natural killer cells
Miscellaneous (E.N.T.)