A 60-year-old woman presents with generalized edema, skin ulceration and hypeension. Urine examination shows subnephrotic proteinuria
Answer is B > C (Essential mixed cryoglobulinemia): The presence of skin ulceration on clinical examination in a female patient around the 6th decade ors a diagnosis of Essential Mixed Cryoglobulinemia over MPGN. Neveheless if Essential Mixed Cryoglobulinemia were not amongst the options MPGN would be the single best answer of choice. Membranoproliferative glomerulonephritis is a responsible for 80% of all renal lesions in essential mixed cryoglobulinemia.
Post-streptococcal Glomerulonephritis
Essential Mixed Cryoglobulinemia
Membranoproliferative Glomerulonephritis (MPGN)
Focal SegmentalGlomerulosclerosis (FSGS)