A 15 year old boy with paial seizure who develops secondary generalization with tonic clonic seizures should be given
Carbamazepine or Oxcarbamazepine are the drug of choice for paial seizures with or without secondary generalization. Choice of AED according to the epileptic syndromes: No Epilepsy syndrome First line AED Second line AED 1 Juvenile Myoclonic Epilepsy VPA PB, CZP 2 Progressive Myoclonic Epilepsy VPA CZP 3 Lennox Gastaut Syndrome VPA, LTG, TPM CZP, LEV 4 Infantile Spasm ACTH, VGB VPA, CLB 5 Benign Rolandic Epilepsy CBZ, VPA, LTG PHT, LEV 6 Sever Myoclonic Epilepsy of Infancy CLB,CZP, VPA LEV, Stiripentol 7 Landau Kleffner Syndrome VPA, LTG, STEROIDS LEV, TPM 8 Myoclonic Astatic Epilepsy CZP, ZLB, VPZ LEV, LTG
Oxycarbamzepine
Zonisamide
Lacosamide
Gabapentin
JIPMER 2019