The receptor involved in chemotheraphy induced vomiting is:
Ondansetron:- It is the prototype of the new class of selective 5-HT3 antagonists that have shown efficacy in controlling nausea and vomiting following administration of highly emetic anticancer drugs and radiotherapy. Ref:- kd tripathi; pg num:-175 Ondansetron is the DOC for early vomiting and nausea due to chemotheraphy and radiotherapy.
Histamine H1 receptor
Serotonin 5-HT3 receptor
Dopamine D2 receptor
Opioid m receptor
Autacoids