Which of the following statements about Cushing's disease is true?
Cushing's syndrome is due to increased adrenal coisol production, regardless of aetiology.Cushing's disease usually is caused by a pituitary microadenoma producing high adrenocoicotropin (ACTH) levels.In most patients, coisol levels would be suppressed as a result of the high-dose dexamethasone suppression test.Transsphenoidal microsurgical removal of the microadenoma is the treatment of choice in most centres.
Serum adrenocoicotropin (ACTH) levels usually are low
Pituitary microadenoma usually is present
There is a high incidence of nonendocrine tumors
Nonsuppression of coisol production by the high-dose dexamethasone suppression test is a characteristic finding
All India exam