Hyperosmolar agents in glaucoma acts by ?
To decrease vitreous volume: Preoperative use of hyperosmotic agents like 20 percent mannitol or oral glycerol is suggested. Mechanism of action:Hyperosmotic agents increasethe plasma tonicity. Thus, the osmotic pressuregradient created between the blood and vitreousdraws sufficient water out of the eyeball, therebysignificantly lowering the IOP. Ref.AK Khurana 4th edition page no 426
Increasing aqueous outflow
Decreasing vitreous volume
Decrease aqueous production
Facilitate uveoscleral outflow
Glaucoma