Primary component of nonadrenergic noncholinergic nerve transmission in gut is:
Vasoactive intestinal peptide (VIP) It is usually produced by neurons It is a potent vasodilator, cause smooth muscle relaxation, increases blood flow and epithelial cell secretion It is the primary component of nonadrenergic noncholinergic neurotransmission in gut along with nitric oxide (NO). Lack of VIP innervations plays a role in achalasia and Hirschsprung disease. Ref: Sleisenger and Fordtran's, Edition-9, Page-7.
VIP and NO
VIP and CCK
VIP and Motilin
VIP and substance