Dextran is a good plasma expanders, but it has disadvantage of:
Essentials of medical pharmacology, seventh edition, page no 645, Answer is option 1, intere with blood group matching It may interfere with blood grouping and cross matching. It can also interfere with coagulation and platelet function.
Interference with blood group matching
Causes thrombocytopenia
Decreases microcirculation
Promote roleaux formation
Hematology