Hypothalamic amenorrhoea is seen in :
Ans. is c i.e. Kallman Syndrome Lets see all options one by one. Asherman's syndrome Is caused by endometrial synechiae most common after an over zealous curettage. The defect lies in the endometrium (Compament I) Stein Leventhal syndrome The polycystic ovarian disease involves the ovaries (Compament II) Sheehan's syndrome This syndrome results from ischaemic necrosis of the Anterior Pituitary (Compament Ill) Kaltman syndrome This syndrome results from defective Hypothalamic GnRH synthesis and is associated with anosmia or hyposmia due to olfactory bulb agenesis or hypoplasia. (i.e. Kaltman syndrome involves hypothalamus or Compament IV). Also know : Kaltman syndrome may be associated with : Optic atrophydeg * Color blindnessdeg Nerve deafness * Cleft palate Renal anomalies * Cryptorchidismdeg Neurologic abnormalities Males with Kaltman syndrome present with : Delayed pubey I Due to low LH, FSH and testosterone levels Micropenis Anosmia Females present with : - Primary amenorrheadeg Failure of secondary sexual developmentdeg - Anosmia. Management : Cyclical estrogen / progestin therapy or gonadotropins. Extra Edge Other congenital hypothalamic syndromes leading to Amenorrhea are : Prader willi syndromedeg * Laurence Moon Biedl syndromedeg Septo-optic dysplasiadeg * Frohlich's syndrome.deg
Asherman syndrome
Stein leventhal syndrome
Kallman syndrome
Sheehan's syndrome