All the following statements are true, except?
Side effects of clozapine- Agranulocytosis (dose independent)- Seizures (dose dependent)- Sedation (m/c)- Myocarditis * Clopidogrel & ticlopidine both are prodrugs (inactive)* Activated by CYP 2C19* Omeprazole inhibits CYP2C19* Reversible P2Y12 inhibitors - cangrelor, ticagrelor SNRI (|5H & |NA), DOC for severe depression- Venlafaxine- Duloxetine- Milanacipran- Des venlafaxine- Levo milanacipran. Coronary steel phenomena shown by- Hydralazine- Isoflurane- Dipyridamole- Enflurane
Dipyridamole shows coronary steel phenomena
Omeprazole inhibit CYP 2C19
SNRI are drug of choice for severe depression
Agranulocytosis is the most common side effect of clozapine
Psychiatric Illness