FALSE statement regarding Hirschprung disease is
Ans. (d) No passage of stools after per rectal examination style="font-size: 1.04761904761905em; font-family: Times New Roman, Times, serif">(Ref: )Most cases of Hirschsprung disease are diagnosed in the newborn period. Hirschsprung disease should be considered in any newborn that fails to pass meconium within 24-48 hours of birth-option b trueDistal intestinal segment that lacks both the Meissner submucosal and the Auerbach myenteric plexus. - option a is trueProximal to aganglionic segment, colon undergoes progressive dilationRectal examination may demonstrate a tight anal sphincter and explosive discharge of stool and gas - option d is falseA rectal suction biopsy can detect hypertrophic nerve trunks and the absence of ganglion cells in the colonic submucosa, confirming the diagnosis.- option c is trueDown syndrome (trisomy 21) is the most common chromosomal abnormality associated with the disease, accounting for approximately 10 percent of patients
Aganglionosis always involves distal rectum
Non passage of meconium in first 24 hours is a cardinal feature
Diagnosis is established by Suction rectal biopsy
No passage of stools after per rectal examination
G.I.T.