How does staph aureus become resistant to methicillin:
Ans. (c) TranspeptidaseRef: Microbiology by Ananthanarayan and Paniker 8th ed. /197, 201-202Resistance develops due to alteration in transpeptidase (penicillin binding protein) on which all beta lactam antibiotics act- so MRSA is resistant to all b-lactam antibiotics.
Heat shock protein
Protein A
Transpeptidase
Protein C
Staphylococci