All true about sodium Thiopentone except -
Thiopentone is ultrasho acting barbiturate. Thiopentone does not produce analgesia and may even produce antianalgesia by reducing the pain threshold. Thiopentone has rapid onset of action (within 30 s) due to high lipid solubility and high non ionized fraction (60%). And ultra-sho duration of action (within 20 mins) due to rapid redistribution. Thiopentone does not completely suppress airway responses to laryngoscopy and intubation and may lead to bronchospasm in asthmatics. Thiopentone is cerebro protective: It reduces CSF volume by facilitating its absorption. It decreases CBF and cerebral blood volume, thus lowering intracranial pressure. It also has anticonvulsant propey which is advantageous in neurosurgical patients who are at increased risk of seizures.
It is intermediate acting barbiturates
It is cerebroprotective
It is agent of choice for narcoanalysis
It is contraindicated in acute intermittent porphyria
Intravenous Anesthetic Agents