After binding of complement and antibody on the surface of encapsulated bacteria, the process of phagocytosis by polymorphonuclear leukocytes/macrophages is enhanced by all of the following opsonins, except?
The efficiency of phagocytosis is greatly enhanced when microbes are coated with opsonins for which the phagocytes express high-affinity receptors. The major opsonins are immunoglobulin G (IgG) antibodies, the C3b breakdown product of complement, and ceain plasma lectins, notably mannose-binding lectin and collectins, all of which are recognized by specific receptors on leukocytes. CD11b/CD18 (MAC-1) is macrophage integrin which help in binding of microbes to macrophages, and are not opsonins.
C3b complement protein
IgG antibody
Mannose binding lectin (MBL)
CD11b/CD18
Extravascular Changes