Which of the following statement about phenytoin is true
Zero-order elimination kinetics: Elimination of a constant quantity per time unit of the drug quantity First order elimination kinetics: Elimination of a constant fraction per time unit of the drug quantity Phenytoin is metabolized in the liver by hydroxylation and glucuronide conjugation. The kinetics of metabolism is capacity limited; changes from first order to zero order over the therapeutic range ref: KD Tripathhi 8thh ed.
It follows zero order kinetics
It is not teratogenic
It is excreted unchanged in urine
It does not induce microsomal enzymes
Central Nervous system