Massive transfusion in healthy adult male can cause hemorrhage due to: March 2011
Ans. B: Dilutional thrombocytopenia Massive blood transfusion causes dilutional coagulopathies especially dilutional thrombocytopenia (stored blood has no platelets and concentration of other clotting factors is also very less)
Increased tPA
Dilutional thrombocytopenia
Vitamin K deficiency
Decreased fibrinogen