Not a feature of Minimal change disease:
Minimal Change Disease M/c cause of development of nephrotic syndrome in child (2-6 yrs) Primary cause (idiopathic, most common) Secondary cause (NSAIDS/Hodgkin's lymphoma/ atopy) Selective proteinuria C/F Excessive frothiness of urine Facial edema No role of immune complexes Good response to steroids
Good response to steroids
Effacement of podocytes on electron microscope, normal on light microscope
Nil deposit disease
NSAIDS is the primary cause
Systemic Pathology