Mechanism of action of Silodosin:
MEDICAL THERAPY IN BPH * Alpha-blockers: (Prazosin, terazosin, doxazosin, tamsulosin, alfuzosin, silodosin) Relaxes smooth muscle & decreases urethral resistance. Side effects: ohostatic hypotension, dizziness, tiredness, retrograde ejaculation, rhinitis & headache. * 5-Alpha-reductase Inhibitors: (Finasteride, dutasteride, triptorelin pamoate)
Alpha antagonist
Beta antagonist
Anticholinergic
PDE5 inhibitor
Prostate and seminal vesicles