Which of the following dopamine agonists used in treatment of parkinsonism is available as a transdermal patch but not oral formulation?
Both ropinirole and pramipexole are available as orally administered immediate (tid) and extended-release (qd) formulations. Rotigotine is administered as a once-daily transdermal patch, and may be useful in managing surgical patients who are NPO. Apomorphine is a dopamine agonist with efficacy comparable to levodopa, but it must be administered parenterally as it is rapidly and extensively metabolized if taken orally. Ref harrison 20th edition page 3127
Apomorphine
Ropinirole
Rotigotine
Pramipexole
C.N.S