The elongation of fatty acids occurs in which of the diagrammatic structures shown in the Illustration?
Ans. C. Structure Ca. Fatty acid synthesis in the cytosol terminates at palmitate, a C16 saturated fatty acid. Elongation of acyl groups can occur from palmitate as well as from other dietary saturated and unsaturated fatty acids of lengths C10 and greater.b. Longer-chain elongation of fatty acids occurs in the endoplasmic reticulum (structure C) using malonyl CoA as the acetyl donor and NADPH as the reductant. Very-long-chain and long-chain fatty acids are preferentially catabolized in peroxisomes (structure J).c. Other structures diagrammed in the figure are the plasma membrane (A), mitochondrion (B), nucleoplasm (D), nucleolus (E), Golgi apparatus (F), secretory vesicles (G), caveolae such as those taking up low-density lipoprotein from its receptor (H), and lysosomes (I).
Structure A
Structure B
Structure C
Structure D
Structure & Function of Protein