The following statements are true for the therapy with lithium except:
Ans. (D) Sodium ion is an specific antidote for lithium clearance(Ref: KDT 8/e p476-477)There is no specific antidote for lithium.Lithium is the drug of choice for the treatment of bipolar disorder and prophylaxis of acute mania.It is a narrow therapeutic index drug and requires therapeutic drug monitoring.Amiloride is the drug of choice for lithium induced diabetes insipidus.
It is used in bipolar disorder
Amiloride is useful in treating lithium induced diabetes insipidus
Regular measurements of blood concentration of lithium is necessary
Sodium ion is a specific antidote for lithium clearance
C.N.S