Diagnosis of X linked agammaglobuliflem should be suspected if-
X-linked disorders Males have only one X chromosome; consequently, a daughter always inherits her father's X chromosome in addition to one of her mother's two X chromosomes. A son inherits the Y chromosome from his father and one maternal X chromosome. Thus, the characteristic features of X-linked inheritance are (1) the absence of father-to-son transmission, and (2) the fact that all daughters of an affected male are obligate carriers of the mutant allele
Absent tonsils and no palpable lymph nodes on physical examination
Female Sex
High Isohemagglutinins titers
Low CD 3
Immune system