Thiopentone is contraindicated in ?
Ans. is 'a' i.e., Acute intermittant porphyria Thiopentone It is an ultrasho acting barbiturate. It has sho duration of action due to rapid redistribution. It causes fall in BP due to vasodilatation - Cardiovascular collapse may occur if hypovolemia, shock or sepsis are present. It can cause respiratory depression. It has anticonvulsant action - agent of choice for neurosurgical procedures. It is the agent of choice for cerebral protection. because it decreases ICT, and cerebral metabolic rate. Miller 6th/e - 330, 332 .o It is poor analgesic -f painful procedure should not be done.It produces hyperalgesia. It has poor muscle relaxant propey. Extravasation of the solution or inadverent intraerial injection produces intense pain - thrombosis and vasoconstriction can cause necrosis and gangrene. Treatment of this condition includes. Leaving needle insitu Brachial block Heparin injection to - prevent thrombosis Dilution of thiopentol t by injection of saline into the aery. Papaverine injection - to relieve spasm. Urokinase, streptokinase, vasodilators, steroid and lignocaine can also be used. Contraindications Acute intermittant porphyria Cardiovascular instability or shock. Respiratory obstruction No availibility of airway equipments. Status asthmaticus
Acute intermittant porphyria
Electro convulsive therapy
Sarcoidosis
Diabetic patients