Drug of choice for precocious puberty in girls is:
Ans. (A) GnRH analogue(Ref: Harrison 19th/2380, KDT 8/e p264)Long-acting gonadotropin releasing hormone (GnRH) agonists are the current therapy of choice for central precocious puberty. In girls, mostly central precocious puberty is seen.GnRH agonists are not effective as therapy for peripheral precocious puberty. Androgen antagonists, spironolactone, aromatase inhibitors (Anastrozole and Letrozole), ketoconazole, and medroxyprogesterone acetate are used to treat peripheral precocious puberty.
GnRH analogue
Danazol
Cyproterone acetate
Medroxy progesterone acetate
Endocrinology