Concerning the central chemoreceptors, True is:
The central chemoreceptors are located near the ventral surface of the medulla; They do not respond to the PO2 of blood; for a given rise in PCO2 , The CSF pH falls more than that of blood because the CSF has less buffering. The bicarbonate concentration of the CSF can affect the output of the Central Chemoreceptors by buffering the changes in pH.
They are located near the dorsal surface of the medulla
They respond to both the PCO2 and the PO2 of the blood
They are activated by changes in the pH of the surrounding extracellular fluid
For a given rise in PCO2, the pH of cerebrospinal fluid falls less than that of blood
Respiratory System Pa 3