True statement regarding development of drug resistance in MRSA is ?
Methicillin resistance occurs due to altered PBPS, thus no penicillin, (Infact no beta-lactam antibiotic) is useful against methicillin-resistant Staphylococcus aureus (MRSA) infections.
Results due to penicillinase enzyme production
Occurs due to change in penicillin binding proteins
Chromosome mediated
Treated with amoxicillin + clavulanic acid