Clonus is due to?
Ans. A Upper motor neuron damageRef: Ganong, 25th ed. pg. 233Clonus is characterized by repeated rhythmic contractions of muscle subjected to sudden maintained stretch.It is Caused by* Increased Gamma motor neuron discharge* Spinal cord injury causing damage to Renshaw cell which is an inhibitory inter-neuron.Conditions in Which Clonus is seen:1. Amyotrophic lateral sclerosis2. Stroke3. Multiple sclerosis4. Spinal cord damage5. Hepatic encephalopathyClonazepam and botulinum toxin is useful in management of clonus.
Upper motor neuron damage
Lower motor neuron damage
Extrapyramidal damage
Cerebellar damage
Nervous System