Which one of the following is an absolute contraindication to the use of thrombolytic agent in the setting of an acute anterior wall myocardial infarction-
Ref: R. Alagappan Manual for Medicine 4th Edition pg no:188-189 Contraindications for Thrombolytic Therapy Absolute contraindications: Active bleeding Defective haemostasis Recent major trauma Surgical procedures < 10 days Invasive procedures < 10 days Neurosurgical procedure < 2 months GI/genito-urinary bleeding < 6 months Stroke/TIA < 12 months Prolonged CPR > 10 minutes H/O CNS tumour, aneurysm, AV malformation Active peptic ulcer Aoic dissection Acute pericarditis Active inflammatory bowel disease Active cavitary lung disease Pregnancy Relative contraindications: Systolic BP > 180 mm Hg Diastolic BP >110 mm Hg Bacterial endocarditis Haemorrhagic diabetic retinopathy H/O intraocular bleeding Chronic warfarin therapy Severe renal or liver disease Severe menstrual bleeding
History of CVA with hemiparesis one month ago
Diabetic retinopathy
Patient's age more than 70 years
Patients is on warfarin for A.F with INR ration 1:8
C.V.S