Which of the following is not a major criteria for diagnosis of multiple myeloma ?
In the NCCN guidelines, active multiple myeloma is no longer diagnosed using the CRAB criteria (hyperCalcemia, Renal failure, Anemia, Bone lesions) for end-organ damage. The current diagnostic criteria are as follows : Bone marrow clonal plasma cells >=10% or bony or extramedullary plasmacytoma (confirmed by biopsy)
Lytic bone lesions
Plasmacytoma on tissue biopsy
Bone marrow plasmacytosis > 30%
`M' spike > 3g% for 1g G, > 2g% for IgA
Haematology