Steroid resistant nephritic syndrome is caused by mutation in which of the following?
A mutation in the Nephrin (NPHS1) gene causes a hereditary form of congenital nephrotic syndrome with minimal change glomerular morphology whereas mutations in NPHS2 encoding for podocin results in steroid resistant nephrotic syndrome. Ref: Robbins 7Th Ed Page 981, 983.
Nephrin
Alpha-actinin-4
Podocin
Transient Receptor Potential 6