Commonest of female cause pseudohermaphrodism ?
Ans. is 'a' i.e., CAH Female pseudohermaphroditism. Gentotype is XX Gonads are ovaries External genitalia are virilized (male differentiation). As there is no mullarian inhibiting factor, mullarian duct develops into uterus tubes and ovary. But due to presence of androgen external genitalia are virilized. Causes are: Congenital adrenal hyperplasia(most common) 21 hydroxylase deficiency 11 beta hydroxylase deficiency Maternal virilizing tumor Arrhenoblastoma Maternal medications with androgen.
CAH
Maternal ovarian tumor
Maternal drug intake
Chromosomal abnormalites