Type IV hypersensitivity reaction is mediated by which of following?
Ans. b (Active T cells). (Ref. Textbook of Microbiology by Anantanarayan, 6th/l 55)HYPERSENSITIVITY REACTIONSHypersensitivity Reaction typePrototypeImmune MechanismsImmediate (type I)AllergiesAnaphylaxisBronchial asthmaCasoni's test (JK'09)Production of IgE antibodyAntibody mediated/ CYTOTOXIC (type II)Autoimmune hemolytic anemia; GBSProduction of IgG, IgM absImmune complex mediated (type III)Autoimmune diseases (SLE, RA, etc),Some bacterial, viral and parasitic infections (e.g. PSGN, Hepatitis B, malaria, etc), Disseminated malignancies,Serum sickness, Arthus reaction(Necrotizing vasculitis).Deposition of ag-ab complexes and complement activationCell-mediated (type IV)Contact dermatitisMultiple sclerosisType-1 DM,TB,Transplant rejectionActivated T-Lymphocytes Macrophage activation T-cell mediated cytotoxicity.Type VGrave's diseaseLATS
B cells
Active T cells
NK cells
Plasma cells
Immunity