Why quinine is unsafe in pregnancy?
Ans. is 'a' i.e., It causes hemolysis Quinine occasionally causes hemolysis, especially in pregnant women and in patients with falciparum malaria resulting in hemogloginuria and kidney damage. Also if used in pregnancy special care should be taken to prevent hypoglycemia. Ouinine It is levo rotatory alkaloid obtained from cinchona bark. Its d-isomer quinidine is used as an antiarrhythmic. Quinine is an erythrocytic schizontocide for all species of plasmodium. Quinine has no effect on pre and exoerythrocytic stage. Mechanism of action is similar to chloroquine.
It causes hemolysis
It causes hypokalemia
It causes hyponatremia
It causes smooth muscle contraction