Lesions of which of the hypothalamic nuclei cause diabetes insipidus:
b. Supraoptic and paraventricular nuclei(Ref: Nelson's 20/e p 348-349, Ghai 8/e p 511)Vasopressin, a 9-amino-acid peptide, has both antidiuretic and vascular pressor activity and is synthesized in the paraventricular and supraoptic nuclei of the hypothalamus.Deficiency of Vasopressin is responsible for Diabetes insipidus.
Dorsomedial nuclei
Supraoptic and paraventricular nuclei
Median preoptic nuclei
Ventromedial nuclei
Endocrinology