All of the following are features of Hyper-IgE syndrome, except:
Hyper-IgE syndrome is autosomal dominant and is a complex disorder that combines skin infections, inflammation, and susceptibility to bacterial and fungal infections of skin and lungs, with characteristic syndromic signs such as facial dysmorphy, hyperextensibility, scoliosis, and osteoporosis. Elevated serum IgE levels are typical of hyper-IgE syndrome. Ref: Harrisons Principles of Internal Medicine, 18th Edition, Page 482.
X-linked recessive inheritance
R/c infections of skin and lung
Hyperextensibility of joints
Facial dysmorphy