In essential lhypeension the drug prescribed with least cardiovascular effect
Aldosterone Antagonists Spironolactone is a nonselective aldosterone antagonist that may be used alone or in combination with a thiazide diuretic. It may be a paicularly effective agent in patients with low-renin essential hypeension, resistant hypeension, and primary aldosteronism. ref:Harrison&;s principles of internal medicine,ed 18,pg no 3079
Clonidine
Alpha blocker
Beta blocker
ACE inhibitor
C.V.S