Anti inflamatory action of coicosteroids is due to blocking of
Breakdown of phospholipids cause the release of phospholipase A2 from the cell membrane Coicosteroid helps in induction of lipocoins in macrophages. Lipocoins inhibits phospholipase A2. This lead to decreased production of prostaglandins, Leukotriens.Thus pro inflammatory mediators are reduced. (REF.Essential of medical pharmacology K D TRIPATHI 6 Edition, Page No - 279)
15 lipoxygenase
Prostaglandin synthetase
Thromboxane synthetase
Breakdown of phospholipids
Endocrinology