Contraction of endothelial cytoskeleton in acute inflammation leads to
Increased vascular permeability is the hallmark of acute inflammation.

Remember

Early transient increase is due to = Endothelial cell contraction
Delayed transient increase in permeability is due to = Direct endothelial injury
Delayed permanent increase Endothelial cell retraction is due to = endothelial cell damage
Delayed transient increase in permeability
Early transient increase in permeability
Delayed permanent increase in permeability
Early permanent increase in permeability