Which of the following plasminogen activator (fibrinolytic) can be given as bolus dose in patients with acute myocardial infarction:
Essentials of medical pharmacology, seventh edition, page no =627 Answer is option3, reteplase It is a modified form of -PA that is longer acting, but somewhat less specific for fibrin bound plasminogen. The longer duration of action enables bolus dose administration, 10mg over 10 minutes repeated after 30minutes.
Urokinase
Alteplase
Reteplase
None
Hematology