All are true regarding Hodgkin&;s lymphoma, except -
<p>Hodgkin lymphoma arise in a single lymph node or a chain of lymph nodes & typically spread in a stepwise fashion to anatomically contiguous nodes. Extranodal involvement is uncommon.</p><p>Reference : Robbins basic pathology 9th edition pg no 440</p>
CNS is the commonest site of involvement
Characteristic cell is a Reed Sternberg cell (AI2K)
Mediastinal involvement is common in nodularsclerosis type
Eosinophils, plasma cells and neutrophils increase
Haematology