Hereditary retinoblastoma develop as a result of which of the following chromosomal deletion?
Hereditary retinoblastomas develop from the deletion of Rb gene, located on chromosome 13q14. Retinoblastoma gene is a tumor suppressor gene, which serves as a break on the advancement of cells from the G1 to S phase of cell cycle.Ref: Robbins Pathologic Basis of Disease, 7th Edition, Pages 287, 289, 1372.
13q 14
13p 14
14p 13
14q 13