Drugs of the choice for central diabetes insipidus is
*Desmopressin is treatment of choice for central diabetes insipidus. *It acts selectively at V2 receptors to increase urine concentration and decrease urine flow in a dosedependent Manner. *It is also more resistant to degradation than AVP and has a three- to fourfold longer duration of action. *Desmopressin can be given by IV or SC injection,nasal inhalation,or oral tablet.
Desmopressin
Leuprolide
Thiazide diuretics
Insulin
Endocrinology