Acetyl CoA cannot be conveed to:
Acetyl CoA is a staing material for Fatty Acid Synthesis, Cholesterol Synthesis & Ketone Body Synthesis (option a, c & d). But Acetyl CoA is never a substrate for Gluconeogenesis i.e. it can never form glucose (option b). Because Acetyl CoA can never be conveed back to Pyruvate as Link reaction or Pyruvate Dehydrogenase is irreversible. However, acetyl-CoA can stimulate gluconeogenesis by activating pyruvate carboxylase (see fig) Extra Edge: Acetyl CoA is NOT:- Not The intermediate of TCA. The first substrate of TCA. The carrier of TCA .
Fatty Acids
Glucose
Ketone Bodies
Cholesterol
Fat and Carbohydrate interconversion