What is the line of treatment for intractable Sydenham chorea?
Ans. b. ValproateRef: Inflammatory and Autoimmune Disorders of the Nervous System in Children by Russell; Page No- 130Sydenham chorea remains the most common cause of acute chorea in children world-wide.It has been firmly established that Sydenham chorea is a complex neuropsychiatric condition, encompassing motor, sensory, and behavioural abnormalities.Although Sydenham chorea is an immune-mediated complication of streptococcus infection, details of its pathogenesis remain to beelucidated.Treatment with Valproic acid, neuroleptics, or, in selected cases, corticosteroids, is effective in the majority cases.
Haloperidol
Valproate
Warfarin
Risperidone
C.N.S.