Rate limiting enzyme in the synthesis of cholesterol is-
Ans. is 'a' i.e., HMG CoA reductase Cycle / PathwayRate limiting enzymeGlycolysisPhosphofructokinase IGlycogen synthesis (glycogenesis)Glycogen synthaseGlycogenolysisGlycogen phosphorylaseTCA cycleIsocitrate dehydrogenaseFatty acid synthesisAcetyl CoA carboxylaseCholesterol synthesisHMG CoA reductaseKetone body synthesisHMG CoA synthetaseBile acid synthesis7-a-hydroxylaseCatecholamine synthesisTyrosine hydroxylaseUrea synthesisCarbamoyl transferaseNote: Only one important rate limiting enzyme has been mentioned here. Some cycle/ pathways may have more than one rate limiting enzymes, e.g., TCA cycle and glycolysis have three rate limiting enzymes (will be discussed in respective chapter).
HMG CoA reductase
HMG CoA synthetase
Acetyl CoA synthetase
Acetyl CoA carboxylase
Lipid Oxidation and Synthesis