Which of the following is the most common form of persistent trophoblastic disease that follows a non molar pregnancy?
Gestational trophoblastic neoplasia (GTN) Invasive mole: Develops after molar pregnancy only. Very rarely follows other gestations PSTT (Placental Site Trophoblastic Tumor): may follow any type of gestation Choriocarcinoma: 2/3rd cases after normal delivery, 1/3rd cases after molar pregnancy Epitheloid Trophoblastic tumor: remote antecedant pregnancy NOTE: After a nonmolar pregnancy, persistent GTN always has the histologic pattern of choriocarcinoma. Histologic characterization of choriocarcinoma depends on sheets of anaplastic syncytiotrophoblast and cytotrophoblast without chorionic villi. The choriocarcinoma is classically a soft, fleshy, yellow-white tumour with a marked tendency to form large pale areas of ischemic necrosis, foci of cystic softening, and extensive haemorrhage.
Choriocarcinoma
Invasive mole
Placental site trophoblastic tumor
Paial mole
Twin Pregnancy, Molar Pregnancy, Gestational Trophoblastic disease and contraception in special situations (Sour Grapes!)