Cisapride was withdrawn from market due to?
ANSWER: (A) QT ProlongationREF: Lippincott's 4th ed ch: 17See previous question for list of drugs causing QT prolongationInhibition of potassium channels widens the action potential, leading to a prolonged QT interval on the electrocardiogram. Such an effect is associated with increased risk of developing life-threatening ventricular tachyarrhythmias (torsades de pointes). The most common cause of QT prolongation is drug-induced, although it may also be genetic.
QT Prolongation
Increased PR interval
Teratogenicity
Myocardial damage
Anti-Emetic