PRPP (Phospho Ribosyl Pyro Phosphate) is used in :
Phosphoribosyl Pyrophosphate(PRPP) is used in the synthesis of : 1. Purine 2. Pyrimidine 3. Histidine 4. Niacin synthesis from Tryptophan. NOTE: Phosphoribosyl pyrophosphate (PRPP) paicipates in pyrimidine biosynthesis only subsequent to assembly of the pyrimidine ring. PRPP serves as a scaffold for assembly of the purine ring in purine biosynthesis. The first intermediate formed in the de novo pathway for purine biosynthesisis 5-phosphoribosyl 1-pyrophosphate (PRPP).
Purine synthesis & Pyrimidine synthesis
Histidine synthesis
Niacin synthesis
All
Nucleotides