Which of the following statements about warfarin group of oral anticoagulants is FALSE?
Activation of factor II, VII, IX and X are inhibited by warfarin group of oral anticoagulants in presence of vitamin K These anticoagulants do not affect the synthesis of these factors.
They interfere with an early step in the synthesis of clotting factors
Irrespective of the dose administered, their anticoagulant effect has a latency of onset of 1-3 days
Their dose is adjusted by repeated measurement of prothrombin time
They are contraindicated during pregnancy
Hematology