An elderly female presents to the emergency department and was found to have a transmural myocardial infarction. Based on her ECG, she was started on thrombolytic therapy with streptokinase. On further examination, which of the following findings would indicate that the thrombolytic therapy is risky and should be stopped?
Pericardial friction rub
Mobitz Type II block
Significant pericardial effusion on echocardiography
Lower limb vein thrombosis