In acute exacerbations of COPD, noninvasive positive pressure ventilation (NIPPV) is initiated when
In acute exacerbations of COPD, noninvasive positive pressure ventilation (NIPPV) is initiated in patients with respiratory failure, which is defined as Paco2 > 45 mmHg, This results in a significant reduction in moality rate, need for intubation, complications of therapy, and hospital length of stay.Ref: Harrison 19e pg: 1707
Paco2 >45 mmHg
PaO2 <80 mmHg
FEV1 <30
FEV1/FVC <0.7
Respiratory system