Anti-double stranded DNA is highly specific for :
Ans. is 'b' SLE (Ref: Chandrasoma Taylor, 3/e, p 985, Harrison 17/e p 2079 & 16/e, p 1971).Anti-double stranded DNA is specific for SLE, anti-single stranded DNA is not specific.Also remember Anti-Smith (Anti Sm) is also specific* for SLE and is found in 30% cases of SLE.Anti-histone antibody* is specific for drug induced SLE*.
Systemic sclerosis
S.L.E.
Polymyositis
Rheumatic sclerosis
SLE