Which of the following inhalational agents has the minimum blood gas solubility coefficient?
C i.e. Desflurane Pungent volatile anesthetic agents are desflurane, isoflurane, enflurane and etherQ. (Mn-"DIE') Volatile Anesthetic Agent Physical propey Blood/ Gas paition coefficient Xenon Colourless, odourless, nonirritating (i.e. non pungent) 0.115 Low B/G Coeffiecient = Low solubitity in blood i.e. fast induction & rapid recoveryQ Desflurane Pungent (irritating / unpleasant to inhale) 0.42 Nitrous oxide (N20) Colourless, sweet smelling, non irritant (i.e. non pungent) 0.47 Sevoflurane Colourless, non pungent 0.69 Isoflurane Pungent ethereal odor (i e. moderately irritating) 1.4 Mn-"Xena- Dislikes No Save" "IE HEAT" Enflurane Pungent 1.9 Halothane Colourless, non irritating (non pungent/pleasant) odor 2.5 High B/G coefficient = High solubility in blood i.e. Slow induction & slow recoveryQ Ether Extremely irritating (pungent) 12 * Because of lack of chlorine / bromine ions; sevoflurane & desflurane have no effect on ozone layer. Pungent = Unpleasant= Causing Cough = Irritant
Isoflurane
Sevoflurane
Desflurane
Nitrous oxide