True about leukemia in Down's syndrome is
In this group of patients, the repoed event-free survival rates have ranged from 80 to 100%. On the other hand, the outcome of Down syndrome children with acute lymphoblasticleukemia (ALL) has been historically considered worse than the outcome of ALL patients withoutDown syndrom Ref ganong's review of medical physiology 25e
Acute leukemia less common than gen population
AML more common than ALL
Prog in AML is better than gen population
If diagnosed with ALL, should be given higher doses of methotrexate
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