Patient diagnosed as squamous cell intraepithelial lesion which of the following has the highest risk for progression to carcinoma:
Ans. is b, i.e. High grade squamous intraepithelial neoplasiaRef: Shaw 15th/ed, p402; Williams Gynae 1st/ed, p629There are various nomenclatures/classification systems for reporting of Pap smear.The one which is classically used is by WHO, which uses the terms CIN-I, CIN-II and CIN-IIIAnother system as discussed earlier is Bethesda which classified the disease as LSIL=low grade squamous intraepithelial lesion and HSIL high grade squamous intraepithelial lesion and chances of progressing to cancer are maximum with HSIL which includes CIN11, CIN111 and ca in situ.
Low grade squamous intraepithelial neoplasia
High grade squamous intraepithelial neoplasia
Squamous intraepithelial associated with HPV 16
Squamous intraepithelial neoplasia associated with HIV
Carcinoma Cervix