Infant with carnitine deficiency form hypoglycemia due to what reason?
Carnitine deficiency can occur paicularly in the newborn-- and especially in preterm infants--owing to inadequate biosynthesis or renal leakage. Losses can also occur in hemodialysis.This suggests a vitamin-like dietary requirement for carnitine in some individualsSymptoms of deficiency include hypoglycemia, which is a consequence of impaired fatty acid oxidation and lipid accumulation with muscular weakness.Treatment is by oral supplementation with carnitineReference: Harper biochemistry, 30th edition, page no 231
Decreased glycosis
Decreased gluconeogenesis
Increased utilization of glucose
Reduced fatty acid oxidation and ketogenesis
miscellaneous