Which of the following statements about 21 alpha hydroxylase deficiency is false?
Hyperkalemia is seen in this case.Deficiency of 21 hydroxylase results in manifestations of aldosterone deficiency (salt wasting), loss of sodium (hyponatremia), increase in potassium (hyperkalemia). Ref: OP Ghai 6th Edition, Page 490;Harrison 17th Edition, Page 2267; Nelson 18th Edition, Page 2360- 2365
Most common cause of Congenital Adrenal Hyperplasia (CAH) in children
Affected females present with ambiguous genitalia
Affected males present with precocious pubey
Hypokalemic alkalosis is seen