Early stage of trauma is characterized by
Injury Phase (Phase of catabolism):-- Begins at the time of injury and lasts for 2-5 days-- Phase of hypermetabolism-- Stress hormones (coisol, catecholamines and glucagon) and volume control hormones (renin-angiotensin, aldosterone and ADH) are increased. This leads to proteolysis, lipolysis, hyperglycemia and wound healing despite of negative nitrogen balance.* Turning Point:-- Transient period marked physiologically by turning off of the neuroendocrine response and clinically by the appearance of getting well. * Early Anabolic Phase:-- Marked by gain in muscular strength or positive nitrogen balance.* Late Anabolic Phase:-- Marked by gain in weight and body fat or positive caloric balance
Catabolism
Anabolism
Glycogenesis
Lipolysis
Trauma