Drug contraindicated in head injury patients -
Ans. is 'c' i.e., Morphine Precautions and contraindications of Morphine1. Head injury: morphine is contraindicated in patients with head injury (KDT). Reasons are -a) By retaining CO2 it increases intracranial tension which will add to that caused by head injury itself.b) Even therapeutic doses can cause marked respiratory depression in these patients.c) Vomiting, miosis, and altered mentation produce by morphine interfere with assessment of progress in head injury cases.2. Branchial asthma: Morphine can precipitate an attack by its histamine releasing action.3. Hypothyroidism, liver and kidney disease patients are more sensitive to morphine4. Infants and elderly are more susceptible to the respiratory depressant action of morphine.5. It is dangerous in patients with respiratory insufficiency (Emphysema, pulmonary fibrosis, corpulmonale), sudden deaths have occurred.6. Hypotensive states and hypovolemia exagerate fall in BP due to morphine.7. Undiagnosed acute abdominal pain - morphine can aggravate certain conditions e.g., diverticulitis, biliary colic, pancreatitis.8. Elderly male - chances of urinary retention are high.9. Unstable personalities are liable to continue its use and become addicted.
Codeine
Pethidine
Morphine
Mannitol
C.N.S