Trivalent oral polio vaccine contains* type 3 virus -
Ans. is 'c' i.e., 300,000 TC1D 50 Oral (sabin) polio vaccineo It contains live attenuated vimss (type 1, 2 and 3) grown in primary' monkey kidney or human diploid cell culture,o The vaccine containsOver 300.000 TCID 50 of type / poliovirusOver 100,000 TCID 50 of type 2 poliovirusOver 300,000 TCID 50 of type 3 polioviruso Dose - 2 drop (0.1 ml)o Schedule in National Immunization Programme of India.DoseAgeOPV-O (Zero dose)At birthOPV-1OPV-26 weeks10 weeksOPV-314 weeksOPV-B (Booster dose)16-24 monthso Development of immunity - OPV induces local intestinal immunity by production of secretory- IgA as well humoral immunity by inducing production of serum antibodies (IgG). So, it gives protection from paralysis and also prevents infection of the gut by wild viruses.
100,000 TCID 50
200,000 TCID 50
300,000 TCID 50
400,000 TCID 50
Communicable Diseases