Achalasia cardia due to:
Ans. (b) Degeneration and absence of ganglion cells in auerbach plexusRef: Bailey and Love 26th edition, Page 1014* Achalasia cardia is due to loss of ganglion cells in myenteric plexus.* Histology shows loss of inhibitory neurons with a variable degree of chronic inflammation.Important point of difference from Hirschsprung disease:* Dilated segment of Achalasia shows such loss of ganglion cells, whereas dilated Colon in Hirschsprung disease shows normal ganglion cells in dilated part.
Degeneration of myenteric plexus due to toxin
Degeneration and absence of ganglion cells in auerbach' Plexus
Excess of Ganglion cells in auerbach Plexus
Degeneration of meissner's Plexus
Oesophagus