What is true about Histoplasmosis -
Chronic cavitary histoplasmosis is seen in smokers who have structural lung disease (e.g. bullous emphysema) is characterized upper-lobe infiltrates, cavitation, and pleural thickening- mimics cavitary tuberculosis.
Isolation of fungi by culture and demonstration of dimorphism is diagnostic.
Reservoir of infection: Soil
Microconidia (spores) are the infective form and mode of infection is inhalation.
Person to person or animal to man transmission in not known so far for Histoplasmosis.
In early stage it is indistinguishable from TB
Culture is not diagnostic
Mycelial forms are infectious form
Person to person spread occurs by droplet infection