Premature baby at 34wk was delivered & had bullous lesion on body. X ray shows periostitis next investigation is
The above mentioned history is suggestive of Congenital Syphilis.So we will do VDRL of both mother and baby to confirm. Early Congenital syphilis Late Congenital syphilis appearing 2-6 weeks after bih untreated after 2 years of age Rhinitis, or "snuffles" Mucocutaneous lesions Bone changes :Osteochondritis, osteitis, and periostitis detectable by x-ray Long bones Hepatosplenomegaly, lymphadenopathy , Anemia, jaundice , Thrombocytopenia; and leukocytosis. Interstitial keratitis (occurs at 5-25 years of age), Eighth-nerve deafness, Recurrent ahropathy. B/L knee effusions - Clutton's joints. Gummatous periostitis occurs at 5-20 years of age. Classic stigmata -Hutchinson's teeth, "Mulberry" molars , Saddle nose and Saber shins.
ELISA for HIV
PCR for TB
VDRL for mother & baby
HbsAg for mother
Preterm Labour