Indomethacin causes:
a. Closure of ductus in premature neonate(Ref: Nelson's 20/e p 2197)Indomethacin, a Prostaglandin inhibitor is used in medical closure of Ductus arteriosus in preterm neonates with PDA.
Closure of ductus in premature neonate
Patent ductus arteriosus
Closure of ductus in term & premature neonates
Closure of ductus in older children also
C.V.S.