A patient is taking ketoconazole for fungal infection develops cold for which he is prescribed terfenadine. Possible interaction between terfenadine and ketoconazole is
(A) Ketoconazole decreases metabolism of terfenadine# Large amounts of Terfenadine reach systemic circulation if erythromycin, ketoconazole, clarithromycin are concurrently administered, as these drugs are P450 enzyme inhibitors.> Azithromycin, fluconazole have no effect & found to be safe.
Ketoconazole decreases metabolism of terfenadine
Terfenadine increases levels of ketoconazole
Ketoconazole decreases levels of terfenadine
No interaction
Miscellaneous (Pharmacology)