Dose of tetracycline which coloration as well as hypoplasia of enamel:
Many clinical studies revealed that average dose consumption of 20-35 mg/kg body weight / day during tooth formation results in -discoloration. Doses > 35 mg/kg/ day results in both discoloration and hypoplasia of enamel.
5 mg/kg body weight
15 mg/kg body weight
20 mg/kg body weight
50 mg/kg body weight