All true about - cocaine except-
It is ester local anesthetics Cocaine was the first local Anesthetic to be used clinically. It is only natural local anesthetic. Koller introduced this in the field of ophthalmology. It is the only local anesthetic with vasoconstrictor action. It is sympathomimetic and inhibits metabolism of catecholamine.
It is amide local anesthetics
It can produce sympathetic stimulation
It is metabolized by liver
It blocks the presynaptic uptake of norepinephrine and dopamine
Regional Anesthesia