Characteristic skin lesion in Peutz -Jeghers syndrome is
Peutz Jegher syndrome. Peutz-Jeghers syndrome- Autosomal dominant - Lentigens (increased melanocytes leading to hyperpigmented macules) - Site of lentigen - Perioral(lips),Buccal mucosa - Associated with GI polyp. (MC : Jejunal hamaoma)Freckles /ephelides* It is increased localized melanogenesis.* Normally seen in fairer skin colour (Skin type I,II)* Become dark on sun exposure Adenoma Sebaceum is seen in Tuberous sclerosis aka epiloia Cafe au lait macules is seen in Neurofibromatosis (dark color lesion over lighter skin).
Freckles
Lentigens
Adenoma sebaceum
Cafe -au- lait macules
Cells of epidermis