Regarding scoline apnoea all are true except
C i.e. Deficiency of cholinesterase Scoline apnoea is prolonged residual paraysis after administration of succinyl choline (suxamethonium) 1/t apnoea. It can be seen in patients with hereditary (inherited) atypical pseudochdinesterase enzyme (homozygous >>> heterozygous)Q and phase II (non depolerizing) blockQ. Decreased level of normal pseudocholinestrerase (not choline esterase) enzymeQ would usually not result in prolonged apnea unless the surgery was very sho. In other words, in contrast to doubling or tripling of blockade duration seen in patients with heterozygous atypical enzyme or patients with low (normal/typical) enzyme levels, patients with homozygous atypical enzyme will have a very prolonged blockade (4-8 hrs) following Sch administration. Prolonged paralysis (apnoea) should be treated with continued mechanical ventilation until muscle function returns to normal which has reduced moality to very low levelsQ.
Caused by suxamethonium
Cab be inherited
Deficiency of cholinesterase
Moality is very low in recent times with proper management