True about CF-
A positive sweat chloride test indicates that it is likely that the infant or person tested has cystic fibrosis (CF). Positive sweat chloride tests are typically repeated for verification. The results may also be confirmed by CF gene mutation panel testing. Ref Harrison20th edition pg 288
Incidence is 1:2000
Positive Sweat test
Mutation in CFTR gene
May presents as meconium ileus
Kidney