Notch effect in embryogenesis is an example of which type of signalling?
One cell type produces the ligand, which then acts on adjacent target cells that express the appropriate receptor. The responding cells are in close proximity to the ligand-producing cell and are generally of a different type. Paracrine stimulation is common in connective tissue repair of healing wounds, in which a factor produced by one cell type (e.g., a macrophage) has a growth effect on adjacent cells (e.g., a fibroblast). It is also necessary for hepatocyte replication during liver regeneration and for Notch effects in embryonic development, wound healing, and renewing tissues. Ref: Robbins 8th edition, Chapter 3
Autocrine
Paracrine
Endocrine
None of the above