Heat-labile instruments for use in surgical procedures can be best sterilized by -
“Ethylene oxide used mainly by industry for the sterilization of plastic and other thermolabile material that cannot withstand heating" - Greenwood 16th /ep. 74.

Other methods for sterilization of heat labile instruments

- Ionizing radiation
- Formaldehyde in combination with subatmospheric steam.
Absolute alcohol
Ultraviolet rays
Chlorine releasing compounds
Ethylene oxide gas