Duration of action of flumazenil is:
Flumazenil is absorbed orally ;oral bioavailability is ~16% but its not used orally .On I.v .injection ,action of flumazenil stas in seconds &last for 1-2 hours ;elimination t1/2 is 1 hour due to rapid metabolism. REF: KD Tripathi 8th ed.
5 minute
10 minute
20 minute
1-2 hours
Central Nervous system