Mechanism of action of Ezetimibe
Refer kDT 7/e p 641 Ezetimibe is a medication used to treat high blood cholesterol and ceain other lipid abnormalities. Generally it is used together with dietary changes and a statin. Alone, it is less preferred than a statin. It is taken by mouth. It is also available in the combination ezetimibe/simvastatin
Interfere with absorption of bile acids
Interfere CETP
Interfere with the absorption of cholesterol by inhibiting NPCIL1
Inhibitor of PPAR alpha
Cardiovascular system