Which of the following diuretics acts on nephron through interstitium
Ans. is 'd' i.e., Spironolactone(Ref: KDT Vh/e p. 587)Spironolactone is mineralocoicoid (aldosterone) antagonist. It opposes the action of Aldosterone without requiring access to the tubular lumen.Spirinolactone (as well as aldosterone) act from the interstitial side.
Thiazide
Furosemide
Acetazolamide
Spironolactone