Shaswat, A67-year-old male comes to the physician's office complaining of severe pain in the right foot with paleness of right toe. The patient had a history of receiving unfractionated heparin 7 days back. The hemogram of the patient is as shown below: Hb 13.2 g/dL WBC 10000/mm3 Platelet 50000/mm3 Which of the following should be used to treat this condition?
(Ref: Katzung 11/e p592) It is a case of heparin induced thrombocytopenia (HIT). Four 'T' are used to suspect the diagnosis of HIT: Hrombocytopenia Timing of heparin administration (5-14 days) before developing thrombocytopenia Thrombosis OTher causes of thrombocytopenia not evident. DOC for HIT is direct thrombin inhibitors like argaroban.
High dose of Heparin
Platelet infusions
Argatroban
Warfarin
Other topics and Adverse effects