All of the following statements is/are true about post streptococcal glomerulonephritis except -
Only ceain strains of group A Beta-hemolytic streptococci are nephritogenic, more than 90% of cases been traced to types 12,4 & 1, which can be identified by typing of M protein of cell wall. Electron microscopy shows deposited immune complexes arrayed as subendothelial, intramembranous, or most often, subepithelial 'humps' nestled against the GBM. Ref: Pathologic basis of disease ROBBINS 8th edition, pg no:917 & ROBBINS basic pathology 9th edition, pg no:529
Early treatment of streptococcal pharyngitis prevents glomerulonephritis
All cases of streptococcal infection lead to glomerulonephritis
Hump sign may be present
Immune complex deposits are seen
Urinary tract