Which of the following mutation is seen in Cowden syndrome?
Mutation in PTEN gene: Breast tumors Endometrial tumors Skin appendage tumors Thyroid tumors Cowden syndrome: Dysplastic gangliogliocytoma of the cerebellum (Lhermitte Duclos disease), caused by mutations in PTEN resulting in PI3K/AKT signaling pathway PTEN
STK 11 mutation
SMAD 4 mutation
PTEN mutation
PTCH mutation
Tumors