The role of adjuvant in a DPT vaccine is :-
Aluminum hydroxide / phosphate is used as Adjuvant/adsorbent in DPT vaccine ; Binds three components (D,P,T) together Increases immunogenicity / Antigenicity - Thiomersal is added to DPT vaccine as a preservative. - Magnesium chloride is added to OPV vaccine: Provides stability.
Decrease hypersensitivity
Decrease absorption of vaccine
Increase antigenicity
Increase the shelf life of a vaccine
Impoant facts in Immunization, Newer Vaccines