Losaan is similar to enalapril in all of the following features except:
Losaan belongs to the class of ARB'sEnalapril belongs to the class of ACEI ARB's differs from ACE inhibitors in: They do not interfere with degradation of bradykinin: no rise in level of bradykinin, substance P occurs. ARB does not produce cough. With Losaan no significant effect on plasma lipid profile, carbohydrate tolerance or insulin sensitivity has been noted. A mild probenecid- like uricosuric action is produced.
Anti-hypeensive efficacy
Potential to reverse left ventricular hyperophy
Lack of effect on carbohydrate tolerance
Potential to induce cough in susceptible individuals
CHF, Angina Pectoris and Myocardial Infarction