Concomitant administration of this drug with organic nitrates is contraindicated due to marked potentiation of vasodilatory action leading to profund hypotension. This drug is:
(Ref: KDT 6/e p525) Nitrates release No, that acts by increasing cGMP. Phosphodiesterase inhibitors like sildenafil inhibits the breakdown of cGMP. Concomitant use of these two drugs may result in profound hypotension.
Propanolol
Fluoxetine
Hydrochlorothiazide
Sildenafil
Other topics and Adverse effects