Most common dose limiting adverse effect of colchicine is:
Colchicine is the most effective drug for acute attack of gout. However, it is used for patients not responding to NSAIDs because of its adverse effects. Diarrhea and myopathy are major adverse effects.
Sedation
Kidney damage
Diarrhea
Muscle paralysis
NSAIDs, Gout and Rheumatoid Ahritis