A cell cycle specific anticancer drug that acts mainly in the M phase of the cycle is:
Vinca alkaloids (Vincristine, Vinblastine and Vinorelbine) and taxanes (Paclitaxel and Docetaxel) act on M-phase of the cell cycle.
Vinca alkaloids inhibit the formation whereas taxanes inhibit the breakdown of the mitotic spindles.
Cisplatin
Etoposide
Methotrexate
Paclitaxel