All are TRUE about the clinical features of polycythemia rubra vera, EXCEPT:
Polycythemia rubra vera clinical features: Splenomegaly may be the initial presenting sign Aquagenic pruritus Hyperviscosity leads to veigo, tinnitus, headache, visual disturbances, and transient ischemic attacks (TIAs). Systolic hypeension is due to red cell mass elevation. Venous or aerial thrombosis may be the presenting manifestation of PV. Erythromelalgia, is a complication of the thrombocytosis Hyperuricemia with secondary gout, uric acid stones, and symptoms due to hypermetabolism can also complicate the disorder. Ref: Harrison, E-18, P-899
Hepatomegaly is the initial presenting sign
Aquagenic pruritus present
Veigo, tinnitus, headache and visual disturbances are due to hyperviscosity
Systolic hypeension is a feature of increased red cell mass