Side effects of clomiphene citrate include all, EXCEPT:
There is no evidence of teratogenicity observed in humans when the drug used to induce ovulation. Clomiphene increases gonadotropin secretion and stimulates ovulation. It increases the amplitude of LH and FSH pulses without changing pulse frequency. It acts largely at the pituitary level to block inhibitory actions of estrogen on gonadotropin release from the gland and causing the hypothalamus to release larger amounts of GnRH per pulse. Side effects of clomiphene include; Multiple gestation Ovarian hyperstimulation syndrome (OHSS) Ovarian cysts Hot flashes Blurred vision Risk of ovarian cancer Ref: Levin E.R., Hammes S.R. (2011). Chapter 40. Estrogens and Progestins. In L.L. Brunton, B.A. Chabner, B.C. Knollmann (Eds), Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e.
Multiple pregnancy
Increase risk of ovarian ca
Multiple polycystic ovary
Teratogenic effect on offsprings