21 year old female presents with history of mild bilater ptosis, proximal muscle weakness and easy fatiguability which among the following is best in diagnosis this condition
* For diagnosis inject edrophonium 2mg i.v Improvement- myasthenic crisis No improvement or worsening - cholinergic crisis. The Tensilon test uses the drug Tensilon (edrophonium) to help your doctor diagnose myasthenia gravis. Tensilon prevents the breakdown of the chemical acetylcholine, a neurotransmitter that nerve cells release to stimulate your muscles. This prevents muscles from being stimulated and makes muscles easy to tire Ref Harrison20th edition pg 2345
Muscle biopsy
Edrophonium test
Repetitive nerve stimulation
Electro myography
C.N.S