A 48 year of woman was admitted with a history of weakness for two months. On examination cervical lymph nodes were found enlarged and spleen was palpable 2 cm below the costal margin. Her hemoglobin was 10.5 g/dl. platelet count 237 x 109/L, and total leukocyte count 40 x 109/L, which include 80% mature lymphoid cell with coarse clumped chromatin. Bone marrow revealed a nodular lymphoid infiltrate. The peripheral blood lymphoid cells were positive for CD19, CD5, CD20 and were negative for CD79B and FMC(-7). Which one of the following statements in not true about this disease?
Trisomy 12 correlates an aggressive clinical course
Abnormalities of 13q 14 are associated with long term survival
Case with 11q22-23 deletions have excessive lymphadenopathy
t (11;14) translocation is present in most of the cases