Sentinel lymph node biopsy is useful for the following cancer-
Ans. is 'b' i.e., Vulva * The sentinel lymph node is the hypothetical first lymph node or group of nodes reached by metastasizing cancer cells from a primary tumor.* Sentinel node biopsy technique is used in the staging of certain types of cancer to see if they have spread to any lymph nodes. It is done using lymphoscintigraphy with technetium-99m labeled nanocolloid or isosulfan blue dye to identify a sentinel node that would predict the presence or absence of regional nodal metastasis.* The main advantage of this procedure is that it decreases unnecessary lymph node dissections, where it is not necessary, thereby reducing the risk of lymphedema and other complications. The main uses are in breast cancer and malignant melanoma surgery, although it has been used in other tumor types with a degree of success.* Vulvar cancer was the first and most promising gynecological site for the sentinel lymph node biopsy strategy. As it involves a cutaneous tumor, peritumoral injections are easy and the sentinel lymph node is always located in the groin. This is another factor making the vulva an ideal site for sentinel lymph node biopsy. Preliminary studies indicate that a sentinel node can be identified in most of the patients of Ca vulva. Trials are on to determine the accuracy of negative predictive value of a uninvolved sentinel node. As of now complete inguinal-femoral lymphadenectomy is indicated in all stages of Ca vulva except stage la.
Cervix
Vulva
Vagina
Endometrial
Miscellaneous (Gynae)