Hypercoagulability due to defective factor V gene is called
• Mutation in factor V gene is caused by the substitution of glutamine for the normal arginine residue at position 506. It is known as Leiden mutation and it is the most common inherited cause of hypercoagulability.
Note: Lisbon mutation is associated with a mutation in thyroid peroxidase gene.
Lisbon mutation
Antiphospholipid syndrome
Leiden mutation
Inducible thrombocytopenia syndrome