Urea is synthesized in all except
The ammonia from all over the body thus reaches liver.It is then detoxified to urea by liver cells, and then excreted thougth kidneys. Urea is the end product of protein metabolism. Since mammals including humanbeings excrete amino nitrogen mainly as urea , they are referred to as ureotolic.Although , ammonia is toxic and has to be immediately detoxified, in kidney cells, ammonia generated on purposefrom glutamine with the help of glutaminase. REF:DM VASUDEVAN TEXTBOOK ;7th EDITION ;Page no:203
Liver
Kidney
Brain
Spleen
Metabolism of nucleic acids