Endothelium-Derived Relaxing Factor (EDRF) induced vasodilatation is mediated by
Endothelium-derived relaxing factor (EDRF) is produced and released by the endothelium to promote smooth muscle relaxation. The best-characterized is nitric oxide (NO). Some sources equate EDRF and nitric oxide. Although there is strong evidence that nitric oxide elicits vasodilation, there is some evidence tying this effect to neuronal rather than endothelial reactions.Ref: Ganong&;s review of medical physiology; 24th edition; page no: 116
Increased intracellular CGMP
Decreased intracellular CGMP
Increased extracellular cyclic Amp
Decreased intracellular cyclic Amp
Endocrinology