Regarding alpha feto-protein true statement is :
Ans. is a i.e. Major source in fetal life is yolk sac As discussed earlier : "AFP is synthesized early in gestation by the fetal yolk sac and later by the fetal GITand liver." No where it is given that major source is yolk sac so this statement (option "a") is paially correct. AFP levies are not increased in wilms tumour (i.e. option "b" is incorrect). Maximum level of AFP in : -- Fetal serum is at - 13 weeks -- Amniotic fluid is at 13 weeks. Maternal serum is at 28-32 weeks.
Major source in fetal life is yolk sac
Commonly incrased in wilms tumour
Maximum level at 20th week
Half life 5-7 days