XDR-TB is defined as: March 2012
Ans: D i.e. Resistance to atleast INH and rifampicin + any quinolones + atleast 1 injectable 2nd line drug Terminology related to drug therapy of TB MDR/ Multi Drug Resistant TB is defined by resistance to at least rifampicin and isoniazid, with or without other drug resistance Drug resistant TB is defined by the presence of resistance to any first line agent Extensively drug resistant (XDR) TB is defined by resistance to at least rifampicin and isoniazind, in addition to any quinolone and at least one injectable second line agent
Resistance to at least INH and rifampicin +/- other drugs
Resistance to any of the 3 first line drugs
Resistance to all 1st line drugs and any 3 second line injectable drugs
Resistance to at least INH and rifampicin + any quinolones + at least 1 injectable 2nd line drug