Alteplase differs from streptokinase as it
Refer KDT 6/e p606 Fibrinolytics are the drugs which activate plasminogen to form plasmin and thus helps in lysis of thrombus These drugs can cause bleeding as the major adverse effect due to lysis of physiological thrombi as well as due to excessive amount of plasma generated in the circulation
Is longer acting
Is derived from human kidney
Is cheap
Activates plasminogen bound to fibrin
Hematology