Which of the following is not a minor diagnostic criteria for multiple myeloma?
Ans. (c) Plasmacytoma on biopsy(Ref: Wintrobes 12th/pg2377)Durie and Salmon criteria for diagnosis of Multiple myeloma.A minimum of 1 major and 1 minor criterion needed, although (1) + (a) is not sufficient, or 3 minor criteria that must include (a) and (b).However, International myeloma working group 2011 has revised the criteria as mentioned in pretexts.
Lytic bone lesions
Plasmacytosis greater than 20%
Plasmacytoma on biopsy
Monoclonal globulin spike on serum electrophoresis of > 2.5 g/dl for IgG, >1.5 g/dl for IgA
Misc. (W.B.C)