In parathyroid carcinoma
In Parathyroid carcinoma there is excess release of parathormone which results in increased blood calcium levels and decreased bone calcium level. Cytolologic details are unreliable in its diagnosis whereas invasion of surrounding tissue and metastasis are only reliable. Ref: Robbins and cotrans 9e Pg 1102
5-10% incidence
Increased parathromone, decreased calcium in bone
Cytology is diagnostic
Metastasis is essential
Endocrinology