Regarding severe combined immunodeficiency, which is true?
Severe combined immunodeficiency Constellation of genetically distinct syndromes Defects in both humoral & cell-mediated immune response MC form - XLR - so more in males; mutation in g chain subunit of cytokine receptors Remaining - AR; deficiency of enzyme ADA
Adenosine deaminase deficiency
Decreased circulating lymphocytes
NADPH oxidase deficiency
C1 esterase deficiency
General pathology