All is true about ropivacaine except:
Ropivacaine is a long-acting amide local anaesthetic agent and first produced as a pure enantiomer. It produces effects similar to other local anaesthetics reversible inhibition of sodium ion influx in nerve fibres. Ropivacaine is less lipophilic than bupivacaine and is less likely to penetrate large myelinated motor fibres, resulting in a relatively reduced motor blockade. Thus, ropivacaine has a greater degree of motor sensory differentiation, which could be useful when motor blockade is undesirable. The reduced lipophilicity is also associated with decreased potential for central nervous system toxicity and cardiotoxicity. The drug displays linear and dose propoional pharmacokinetics (up to 80 mg administered intravenously). It is metabolised extensively in the liver and excreted in urine.
It is enantiomer of Bupivacaine
Can be safely used in labour analgesia in lower concentrations
It is less potent and less lipid soluble than Bupivacaine
Cardiotoxicity is similar to as that of Bupivacaine
Regional Anesthesia