A 50 year old man presents with paresthesia. Hb = 6.8 gms/dl. Peripheral smear shows macrocytes and neutrophis with hypersegmented nuclei. Endoscopy reveals atroghic gastritis. Which of the following deficiency is more likely?
above clinical features point towards Vit B12 deficiency due to Pernicious anemia. Pernicious anemia -Type II Hypersensitivityin which ABs are formedagainst intrinsic factorthus inhibits the binding of IF+B12. Intrinsic factor deficiency-Malabsorption of vitamin B12 - Megaloblastic anemia /Pernicious anemia
Fotate deficiency
Vitamin B12 deficiency
Riboliavan deficiency
Fotate deficiency
NEET Jan 2020