Ram Devi presented with generalized edema sweating and
The symptoms of the patient are d/t hypersensitivity type I reaction Type I is mediated by IgE and it flairs up within minutes.
The symptoms range from rashes to anaphylactic shock with vasodilatory hypotension and bronchiolar spasm.
Examples of type I
Eczema*
Hay fever*
Asthma*
Anaphylactic shock*
Urticaria*
A cute dermatitis *
Theobald Smith reaction *
Other hypersensitivity reactions
Type II
is characterized by an antigen-antibody reaction on the surface of a host cell*.
Mediated by IgG or IgM.
Examples
1. Blood transfusion reactions *
2. Transplant rejection *
3. Autoimmune hemolytic anaemia*
4. Autoimmune thrombocytopenic purpura *
5. Diabetes disease*
6. Good pasture’s syndrome *
7. Grave's disease*
8. Myasthenia gravis*
9. Pemphigus
0. Pernicious anaemia*
1. Rheumatic fever*
Type HI reactions
Mediated by antigen/antibody complex*.
Examples
1. PAN*
2. Post streptococcal glomerulonephritis*
3. Rheumatoid arthritis*
4. Systemic lupus erythematosus*
5. Acute viral hepatitis*
6. Penicillamine toxicity*
7. Serum sickness*
8. Arthus reaction*
Type IV reaction
Cell-mediated reaction (delayed hypersensitivity)*.
Examples
1. Tuberculosis*
2. Sarcoidosis*
3. Temporal arteritis
4. Contact dermatitis* (not that acute dermatitis in type I)
5. Lepromin test*
6. Patch test*
7. PPD*
T cell mediated cytotoxicity
IgG mediated reaction
IgE mediated reaction
IgA mediated hypersensitivity reaction