Mebendazole used in all EXCEPT
i.e. (Borrellia Recurrentis): (509-KDT 6th)Indication of Mebendazole use are* Round worm-Ascaris - lumbricoides* Hook worm-Ancylostoma duodenale, Necator americanus* Whip worm-Trichuris trichura* Thread worm-Enterobius vermicularis* Trichinella spiralis-Less effective than albondazole* Hydatid disease-Less effective than albendazole MebendazoleParasitic infections - Ascariasis, Capillariasis, eosinophilic enterocolitis, enterobiasis, hook worm, trichinellosis, trichostrongliasis, trichoriasis, visceral larva migrans (1272-H17th)Metronidazole: IndicationsMetronidazole is the drug of choice for sympathetic intestinal and extraintestinal amebiasis as well as infections with Trichomonas vaginalis and Giardia lambia. It is quickly and reliably effective against Gardnerella vaginosis.Anaeobic infections (e.g. cerebral abscesses, intra-abdominal abscesses, gynecological infections of the pelvic organs, soft tissue infections, osteomyelitis) are well documented indications. Metronidazole also has an advantageous effect on parodontopathy. Anaerobic infections of the lower respiratory tract respond better to penicillin or clindamycin. Metronidazole is sometimes more efficient than sulfasalazine for Crohn's disease, however, the tolerance of long-term administration is not established.Applied topically, metronidazole has proven effective against rosacea, acne, and foul-smelling skin lesions (tumours, decubitus ulcer).Borrelia recurrentis - causes louse-borne (epidemic) relapsing fever (1052-H17th)Treatment - Doxycycline (or another tetracycline) erythromycin or chloramphenicol highly effectiveFor children <8 years of age and for pregnant women erythromycin or Penicillin G may be preffered given the potential adverse effects of tetracyclinesTreatment of Giardiasis (*Gierdia lamblia) 1313-H17th* Drug of choice - Metronidazole, other Tinidazole, Nitazoxanide (alternative)* Drug of choice for pregnant women - Paromycin
Borrellia recurrentis
Giardia lamblia
Treponema vincetti
Gardenella infections
Anti Microbial