The following statement is false regarding Grave's
Grave&;s Disease (Diffuse Toxic Goiter)M/C cause of hypehyroidism, caused by stimulatory autoantibodies to TSH-RMore common in females with peak incidence between 40-60 yrsClinical FeaturesHypehyroid symptoms- heat intolerance, increased sweating and thirst, weight loss despite adequate caloric intake.Symptoms of adrenergic stimulation- palpitations, nervousness, fatigue, emotional lability, hyperkinesis, and tremorOlder patients present with CVS complications (CVF and CHF)In Grave's disease- Cardiac toxicity is less and CNS toxicity is more. In secondary thyrotoxicosis cardiac toxicity is more common.(Refer: Schwaz's Principles of surgery, 9th edition, pg no: 1353-1354)
Hyperophy/hyperplasia is due to TSH-RAbs
Cardiac failure is common
Goiter is diffuse and vascular
Remissions and exacerbations are not infrequent
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