Non-immune hydrops fetalis is caused by all except
Immune hydrops fetalis is caused by red blood cell alloimmunisation haemolytic disease. All other causes are described as non-immune hydrops fetalis (NIHF). Hydrops is a symptom of a wide range of conditions which have resulted in an imbalance in fetal fluid between the vascular and interstitial space.Diagnostic criteria are fluid in at least two body cavities (pleural space, pericardial space, peritoneal space, skin or placental enlargement). The prognosis depends on associated prematurity, the underlying cause, the severity of any associated pulmonary hypoplasia and the severity of the ongoing post-natal fluid accumulation. Reference: GHAI Essential pediatrics, 8th edition
Parvo B19 virus
Chromosomal abnormalities
alpha-thalassemia
ABO incompatibility
Genetic and genetic disorders