Which of the following (in maternal serum) indicate open neural tube defect: March 2011
Ans. B: increased Alpha fetoprotein levels MSAFP level is elevated in 1) wrong gestational age, 2) open neural tube defect (NTD's), 3) multiple pregnancies, Rh isoimmunisation 4) IUFD, 5) anterior abdominal wall defects and 6) renal anomalies Risk factors for NTD: Family history of neural tube defects Maternal diabetes insufficient folic acid intake during pregnance Maternal intake of anti-epileptics
Increased folic acid levels
Increased Alpha fetoprotein levels
Decreased Alpha fetoprotein levels
Decreased beta-HCG