The most distinctive feature of pathogenic E. histolytica on fresh stool examination is:
The trophozoites from acute dysentric stools often contain phagocytosed erythrocytes. This feature is diagnostic and distinctive as phagocytosed red cells are not found in any other commensal intestinal amoebae.
Presence of active pseudopodia
Erythrophagocytosis
Presence of intracytoplasmic vacuole
Presence of two nucleoli
Parasitology Pa 1 (Protozoology)