A 20 year old female is diagnosed to have molar pregnancy. All of the following are features of paial mole, EXCEPT:
In a case of paial mole there is only 1-5% risk of development of persistent trophoblastic disease. There is a 15-20% risk for developing this in cases of complete mole. Features of paial mole are: Karyotype is usually 69,XXX or 69,XXY Fetus, amnion and fetal red blood cells are often present Villous edema could be focal or diffuse Trophoblastic proliferation could be variable 1-5% risk of developing persistent trophoblastic disease Ref: Cunningham F.G., Leveno K.J., Bloom S.L., Hauth J.C., Rouse D.J., Spong C.Y. (2010). Chapter 11. Gestational Trophoblastic Disease.
Fetus is present
Amnion is present
Karyotype is usually 69 XXY
Greater risk of persistent trophoblastic disease