Free nerve endings carrying nociceptive fibers are seen in:
Ans. d. MesenteryFree nerve endings carrying nociceptive fibers are seen in mesentery.`Visceral nociceptors are thought to be free nerve endings which occur in the walls of most hollow viscera and mesenteries.'-Applied Basic Science for Basic Surgical training by Andrew T Puffery (2008)/211`The afferent innervations of serosa and mesentery are provided by spinal afferent fibres which are mostly bare nerve endings. By contrast most nerve fibre endings in the muscle layer of the gut comprise two specialized endings -- IGLEs and Intramuscular arrays (IMA) with only a small population of free nerve endings repoed in the intestines. '- Physiology of the Gastrointestinal Tract by Kim E. Barrett, Fayez K. Ghishan, Juanita L. Merchant, Hamid M. Said, Jackie D. Wood p690'Physiologic determinants of pain (nociception) include the nature of the stimulus, the type of receptor involved, the organization of the neural pathways from the site of injury to the central nervous system, and a complex interaction of moding influences on the transmission, interpretation, and reaction to pain messages. Sensory neuroreceptors in abdominal organs are located in the mucosa and muscularis of hollow viscera, on serosal structures such as the peritoneum, and within the mesentery. Visceral pain is transmitted by C fibers that are found in muscle, periosteum, mesentery, peritoneum, and viscera. '- Feldman: Sleisenger and Fordtran's Gastrointestinal and Liver Disease, 9/e
Intestine
Spleen
Liver
Mesentery