Weil-Felix reaction with OXK antigen indicates infection with
Weil-Felix reaction:
Serological diagnosis of Rickessial infection. Weil-Felix reaction is a Heterophile agglutination test. Antigens used are Nonmotile strains of Proteus vulgaris (OX 19, OX 2), Proteus mirabilis (OX K).
Mechanism: Proteus and Rickessiae will share alkali stable carbohydrate antigen will be basis of the Weil-Felix reaction. Weil-Felix is a tube agglutination test. It is a simple and useful test for the diagnosis. The Antibody rises in 2nd week of illness and reaches the peak and get decline rapidly during the course of convalescence.
R. tsustsugamushi
R. mooseri
R. quintana
R. akari