A 25-year-old man is discovered to have colon cancer. It is noted that several members of his family also developed colon cancer at relatively young ages. Which of the following genes is most likely to be involved
Hereditary nonpolyposis colorectal carcinoma, also known as Lynch syndrome, presents as an autosomal dominant disorder characterized by the formation of colon cancer, usually early in life. The disorder is associated with the hereditary nonpolyposis colorectal cancer gene and with the formation of multiple colonic polyps, although fewer than seen in the family adenomatous polyposis syndrome. Ref:- Harsh mohan
p53 gene
K-ras oncogene
Mismatch repair gene
Hereditary nonpolyposis colorectal cancer gene
G.I.T