Which of the following is not true about the poisoning caused by seeds shown below?
The seeds in the given picture are of 'kuchila' or 'Nux vomica' the seeds are highly fatal. Even one crushed seed is fatal. It contains 3 active toxins Principle :- strychnine which (acts on anterior HORN cells of spinal cord) inhibits glycine--> preventing the inhibitory effects of glycine on the post synaptic neuron Neurotransmitter nux vomica poisoning resembles 'tetanus' since it causes muscle convulsion. 3 features are seen:- 1. Opisthotonus (most common) 2. Pleurosthotonus 3. Emprosthotonus After death ' postmoem caloricity' phenomenon occurs i.e initially after death, the patient remains warm for few hours.
Pleurosthotonus
Post moem caloricity
Uncrushed seeds will not lead to poisoning
Toxin potentiates neurotransmitter glycine effect at pre-synaptic receptor
FMT Q Bank