A commonest side effect of Dapsone is :
Hemolysis develops in almost every individual treated with 200-300 mg dapsone per day. Doses of less than 100 mg in healthy persons and less than 50 mg per day in persons with G-6PD deficiency do not cause hemolysis. Methemoglobinemia is also very common.
Hemolytic anemia
Thrombocytopenia
Cyanosis
Bone marrow depression