Acetaminophen poisoning causes which of the following changes in the liver?
Acetaminophen poisoning typically causes centrilobular necrosis in liver. Ref: Harrison's Principles of Internal Medicine, 18th Edition, Page 2560, see Table: 305-1.
Centrilobular necrosis in liver
Microvesicular fatty infiltration in hepatocytes
Cholestasis
Peripoal inflammation