What is the principle behind radiotherapy in malignancy?
Radiotherapy is the treatment of cancer with ionizing radiation. It works by damaging the DNA within the tumor cells, making them unable to divide and grow. The goal of radiation therapy is to maximize the dose to tumor cells while minimizing exposure to normal, healthy cells. Ref: Emami B et al. 1991
Ionisation of DNA
Dehydration of DNA
Charring the nucleus
Ultrasonic effect