Nifedipine and beta-blocker are given together -
Ans. is 'b' i.e., To overcome increased sympathetic activity of Nifedipine b-Blocker is given along with Nifedipine because a) Reflex tachycardia (Increased sympathetic activity) caused due to Nifedipine, is prevented by b-blocker. b) b-blockers cause dilatation of coronary aeries by unopposed a-mediated vasoconstriction. Nifedipine causes coronary vasodilatation and opposes the spasm caused by b-blockers. The tendency of b-blocker to cause ventricular dilatation is counteracted by Nifedipine.
To decrease pedal edema due to nifedipine
To overcome increased sympathetic activity of nifedipine
Anti CHF action of propranolol
Antiarrhythmic effect of nifedipine