In sickle cell crisis bone pain is due to:-
- Abnormal shape of RBC - Occlusion of small vessels of bone - bone infarction - resulting in pain If bones of hand & feet are involved - Hand foot syndrome Long bones - Avascular necrosis of femur veebral column - 'H' shaped veebra/ cod fish veebra/ fish mouth veebra -X ray skull - crew cut appearance (Hair on end appearance)
Bone infarction
Osteroporosis
Osteomalacia
Periosteal reaction
Hemoglobinopathies: Sickle cell anemia