Which disaccharides are not broken down in git?
LactuloseComposition: O-a-d-galactopyranosyl-(1-4)-b-d-fructofuranoseSource: Heated milk (small amounts), mainly syntheticClinical Significance: Not hydrolyzed by intestinal enzymes, but fermented by intestinal bacteria; used as a mild osmotic laxativeFermentation of lactulose results in acidification of the gut contents so that ammonia produced by intestinal bacteria is trapped as ammonium that cannot diffuse into the bloodstream.Fermentation of lactulose results in an eightfold increase in the osmolality of the gut contents so that there is more water for ammonia and ammonium to dissolve in so that less is absorbed into the bloodstream.Ref: Harper&;s Biochemistry, 30th edition, page no: 170, table 15-4
Lactulose
Maltose
Sucrose
Lactose
Metabolism of carbohydrate