Local anaesthesia causing methemoglobineinia -
O-toludine metabolites of prilocaine accumulate after large dose of drug conve hemoglobin to methemoglobin lead to methemoglobulinemia, dose depndent(range of 10mg/kg) Treatment of methemoglobinemia is IV methylene blue Benzocaine also cause methemoglobinemia
Procaine
Prilocaine
Etodicaine
Ropivacaine
Regional anaesthesia