A person is HBsAg positive, but anti-HBsAg negative, what should be the next step
HBsAg indicates a current infection.Anti-HBs is generally interpreted as indicating recovery and immunity from hepatitis B virus infection. Anti-HBs also develops in a person who has been successfully vaccinated against hepatitis B.HBeAg is a hepatitis B viral protein. It is an indicator of active viral replication.HBcAg (core antigen) is a hepatitis B viral protein. It is an indicator of active viral replication.*replicative phase is characterized by the presence in the serum of HBeAg and HBV DNA levels well in excess of 10^3-10^4 IU/mL** chronic HBV infection can occur in the presence or absence of serum hepatitis B e antigen (HBeAg), the level of HBV DNA correlates with the level of liver injury and risk of progression.
Repeat test after 6months
Check if HBeAg is positive
Check HBV DNA load
Reassure the patient
G.I.T