18 year old female presents with an ovarian mass, her serum LDH & placental alkaline phosphate are found to be elevated. What is the treatment of choice in this condition?
The given scenario suggests the diagnosis of Dysgerminoma Most common germ cell malignancy High risk: dysgenetic gonads, testicular feminisation syndrome Tumour markers: LDH, PLAP, (hcg may be raised in some but AFP is normal) In Dysgerminoma, conservative surgery (U/L Salphingo-Oophorectomy) recommended as most patient are Young girls Post operative Chemotherapy gives 90% success NOTE: bilateral salpingo-oophorectomy is not done here in order to conserve ovarian function and feility unless mentioned that the presentation is bilateral.
B/L oophorectomy & post op radiotherapy
Oophorectomy on the involved side
Only chemotherapy
Hysterectomy with bilateral salpingopherectomy
Ovarian Tumors and Vulvar cancer