Which one of the following is true of hyaline membrane disease of the newborn -
Ans. is 'c' i.e., Phosphatidyl glycerol estimation is a reliable method of diagnosis o In HMD surfactant is reduced and its measurement can be used for diagnosis e.g. in shake test. o Constituent of surfactant are - dipalmitoyl phosphatidylcholine (lecithin), phosphatidylglycerol, apoproteins (surfactant proteins ----> SPA, SPB, SPC, SPD) and cholesterol.
Prematurity provides relative protection of the occurrence
Maternal steroid exposure increase severity of the disease
Phosphatidyl glycerol estimation is a reliable method of diagnosis
Surfactant increases the surface tension of a lveoli