True about membranous GN are following except
Ans. is 'b' i.e., Deposition between endothelium and B.M.Membranous glomerulonephritis o Membranous glomerulonephritis, also known as membranous nephropathy, is a slowly progressive disease of the kidney affecting mostly patients between ages of 30 and 50 years.o Membranous glomerulonephritis is classifiedPrimary (idiopathic) - 85%Secondary - 15% Drugs --> Penicillamine, captopril, gold, NSAIDS Malignant tumors --> Lung, colon, melanoma Auto immune conditions --> SLE, thyroiditis Infections HBC, HCV, syphilis, schistosomiasis, malariaMembranous glomerulonephritis is characterized by ?o Diffuse thickening of glomerular capillary wall.o Accumulation of electron - dense, immunoglobulin containing deposits along subepithelial side (between epithelium and GBM).o Membranous glomerulonephritis is the most common cause of nephrotic syndrome in adults.
Thickening of B.M
Deposition between endothelium and B.M.
Most common cause of nephrotic syndrome in adults
Seen in SLE, tumors, drugs