A drug effect that is produced by therapeutic doses of both timolol and amiodarone is blockade of:
Amiodarone has wide spectrum of antiarrhythmic actions. It acts by all the four mechanisms: blockade of Na+ channels blockade of b receptors blockade of K+ channels blockade of Ca2+channels. Timolol is a b blocker. Therefore, common action of these two drugs is inhibition of b-receptors.
Cardiac Na+ channels
Cardiac K+ channels
Beta adrenoceptors
Alpha-adrenoceptors
Hypeension, Arrhythmias, Dyslipidemia