All of the following statements except one are true of medications in the same class as diclofenac:
Diclofenac is a topical ocular NSAID. Other medications in this class include flurbiprofen, ketorolac, nepafenac, and bromfenac. Topical NSAIDs are indicated for the treatment of postoperative inflammation. These medications have been associated with corneal complications, including corneal melt and perforation. The mechanism of action of NSAIDs is by blocking the cyclooxygenase pathway, which eliminates the production of prostaglandins, prostacyclin, and thromboxane.
can be associated with corneal complications, including corneal melt and perforation
can be used for treatment of postoperative ocular inflammation
result in the increased production of thromboxane
result in decreased synthesis of prostaglandins
Miscellaneous