True about Nephrogenic diabetes insipidus is?
ANSWER: (A) Renal tubule unresponsiveness to ADHREF: Harrisons medicine 17th ed 2219In Nephrogenic diabetes insipidus the tubules are unresponsive to the ADH and it could be due to acquired, genetic, drugsParametersPsychogenicpolydipsiaDiabetesinsipidusNephrogenic DIOsmotic diuresisSerum NaN or decIncreaseIncreaseN or incPlasma osmN or decIncreaseIncreaseN or incUrine osmDecdecreasedecreaseIncreasePlasma ADHDecdecreaseIncreaseIncreaseUrine osm after ADHIncreaseincreasenilSlight increase
Renal tubule unresponsive ness to ADH
There is central decrease in secretion of ADH
Serum Na is low
The urine osmolarity is increased after ADH administration
Renal Tubular Disease