In the Clarke's level of tumor invasion of malignant melanoma level 3 refers to:
Clark's level ( on the basis of depth of invasion): EPIRS 1. Melanoma restricting to epidermis & appendages 2. Invading Papillary dermis without filling it 3. Reach Interface of papillary & reticular dermis 4. Invading reticular dermis 5. Invading subcutaneous tissue.
All tumor cells above basement membrane
Invasion into reticular dermis
Invasion into loose connective tissue of papillary dermis
Tumors cell at junction of papillary and reticular dermis
Plastic Surgery and Skin Lesions