Which is not a feature of neoplastic cell?
Ans: d (Nuclear cytoplasmic ratio 1:4)The hallmark of malignant transformation is anaplasia.The morphological changes in anaplasia are:-1) Pleomorphism: by both cell & nuclei2) Abnormal nuclear morphology: HyperchromasiaNuclear cytoplasmic ratio approaches 1:1 (normal is 1:4 or 1:6)Large nucleoli3) Large no of mitoses4) Loss of polarity5) Other changes: tumour giant cells
Hyperchromasia
Pleomorphism
Atypical mitoses
Nuclear cytoplasmic ratio 1:4
Neoplasia