Which of these is the characteristic feature of membranoproliferative glomerulonephritis-
Ans. is 'c' > 'd' ie splitting of glomerular basement membrane > sub endothelial deposits Both the features mentioned in the options d & c are present in membranoproliferative glomerulonephritis.Membranoproliferative glomerulonephritis is of 2 typesTYPE I characterized byDeposition of subendothelial* immune on complexes in the glomerular capillarySplit basement membrane (Double contour or tram track appearance)Type II Characterized by:Dense intramembranous* deposits electron microscopyRemember the only other condition where subendothelial deposits are seen is - SLE.Glomerular depositsSub epithelialDiffuse proliferative glomerulonephritis*Membranous glomerulopathy*.IntramembranousMembranoproliferative glomerulonephritis type II *Mesangial Focal segmental glomerulonephritis*Henoch Schonlein purpura *
Sub epithelial deposits
Foamy cells
Splitting of glomerular basement membrane
Sub endothelial deposits.
Glomerular Diseases