Which of the following drugs is most likely to precipitate angina?
Vasodilators and peripherally acting CCBs (Dihydropyridines) can cause tachycardia and thus may precipitate acute attack of angina. Risk of tachycardia is more with sho acting drugs like nifedipine than with long acting agents like amlodipine. Diltiazem & Verapamil --> decreases HR and also cause vasodilation.
Amlodipine
Nifedipine
Diltiazem
Verapamil
CHF, Angina Pectoris and Myocardial Infarction