Mitochondrial DNA (mt- DN(A) is known for all except -
Ans. is 'd' i.e., Nemaline myopathy results due to mutations in mt- DNA o Nemaline myopathy is not a mitochondria] disorder. o Mitochondrial DNA is always maternally inherited. o Heteroplasmy is the presence of mixture of more than one type of an organelle genome (mt- DNA) within a cell or individual. It is a factor for the severity of mitochondrial disease, since every eukaryotic cell contains many hundreds of copies of mt- DNA; it is possible and indeed very frequent for mutations to affect only some of the copies, while the remaining ones are unaffected.
Maternal inheritance
Heteroplasmy
Leber hereditary optic neuropathy is the prototype
Nemaline myopathy results due to mutations in mt- DNA