Which subtype of Hodgkin lymphoma is associated with maximum incidence of "B" symptoms?
Mixed Cellularity type: Maximum incidence of B - Symptoms i.e. Fever, Weight loss, Night sweats Bimodal distribution - young & older than 55 years of age B Symptoms are d/t cytokines released by the inflammatory cells Maximum inflammatory cells are seen in Mixed cellularity subtype of HL- More secretion of cytokines- more B symptoms. Overall prognosis is very good.
Nodular sclerosis type
Mixed cellularity type
Lymphocyte predominant type
Lymphocyte rich type
Hodgkin's Lymphoma