Fixed drug combination have all advantages except ?
Ans. is 'c' i.e., No dose adjustment in combination preparation. FDCs offer simple dosage schedule which improves patient compliance and therefore improves treatment outcomes. Impoant in elderly patients or patients suffering from multiple disorders. More economic than single ingredient drugs. Such reduced "pill burden" can greatly enhance the overall treatment outcome.
Increased compliance
Decreased incidence of drug resistance
No dose adjustment in combination preparations
Synergistic effect of some drug combinations