Breslow thickness is used in
In melanoma, the probability of metastasis correlates with the depth of invasion, which by convention is the distance from the superficial epidermal granular cell layer to the deepest intradermal tumour cells; this measurement is known as the Breslow thickness.The probability of metastatic spread and prognosis, to predict an outcome is based on the following variables:(1) tumour depth (the Breslow thickness); (2) number of mitoses; (3) evidence of tumour regression (presumably due to the host immune response); (4) ulceration of overlying skin; (5) the presence and number of tumour infiltrating lymphocytes; (6) gender; and (7) location (central body or extremity)Since most melanomas initially metastasize to regional lymph nodes, additional prognostic information may be obtained by performing a sentinel lymph node biopsyRobbins Pathology 9e pg: 1150
Melanoma
Squamous cell carcinoma
Basal cell carcinoma
Actinic keratosis
dermatology and infectious disease