The reaction catalyzed by phosphofructokinase:
Ans. C. Is the rate-limiting reaction of glycolytic PathwayPhosphofructokinase is the key enzyme of glycolysis. It phosphorylates Fructose-6- phosphate to form Fructose 1,6- bisphosphate. It is inhibited by ATP and Citrate ions and allosterically modified by AMP. PFK has two activities. PFK1 forms Fructose 1,6- bisphosphate and PFK2 forms Fructose 2,6-bisphosphate. The former reaction is irreversible and the latter reversible. Fructose 2,6-bisphosphate depicts the energy status of the body.
Is activated by high concentrations of ATP and citrate
Uses fructose-l-phosphate as substrate
Is the rate-limiting reaction of glycolytic Pathway?
Is inhibited by fructose 2, 6-bisphosphate
Carbohydrates