All of the following statement about pralidoxime in organophosphate poising are true except
- Oximes are given for the reactivation of the inhibited Acetylcholinesterase in OPC poisoning - Two oximes which are used : * PAM (Pralidoxime) : does not cross blood brain barrier * DAM (Diacetyl mono-oxime) : crosses blood brain barrier, both central and peripheral action - Oximes should be staed as soon as possible after atropine is given , if we take long time then enzyme aging may occur (enzyme cannot work)
It is given Intravenously
It should be staed after 24 hrs. of poisoning
Does not cross blood brain barrier
Reactivates AchE enzyme
Parasympathetic System & Glaucoma