Anti-diabetic effect of sulfonylureas is by reducing:
Ans. (A) Glucagon production(Ref: KDT 8/e p294)Sulfonylureas act byIncreasing insulin release from pancreas (not by decreasing insulin secretion), so 'option b' ruled out.A minor action reducing glucagon and increasing somatostatin release has been demonstrated.
Glucagon production
Insulin secretion
Tissue sensitivity to insulin
Tissue sensitivity to glycogen
Endocrinology