The major source of estrogen after menopause is?
Androgen production from the ovary continues beyond menopausal transition caused by sparing of ovarian stroma and theca cells. However due to loss of granulosa cell function, ovary does not contribute to estrogen production by aromatization of androgens. The most impoant source of estrogen is peripheral conversion of androgens produced by ovary and adrenals, principally occurring in adipose tissue.
Aromatization of androgens in theca cells of ovary
Aromatization of androgens in granulosa cells of the ovary
Aromatization of androgens in adipose tissue
Adrenal production of estrogens
Normal Menstruation, Abnormal Menstruation, Menopausal Physiology and forsight of conception