Isolated rise in aPTT is seen in?
Isolated rise of APTT are seen in APTT measures the activity of the intrinsic and common pathways of coagulation CAUSES Lupus anti-coagulant (anti-phospholipid syndrome) Heparin exposure Haemophilia A and B (Factor VIII and IX deficiency respectively) Factor XII deficiency Factor XI deficiency Contact factor deficiency e.g. pre-kallikrein (not clinically impoant) Aefactual (incorrect amount of blood in the tube) Ref Robbins 9/e pg 54
Von Willibrand's disease
Factor 7 deficiency
Vitamin K deficiency
Anti phospholipid antibodies
Haematology