Raju, a 10 yr old boy is having difficulty in learning at school. He has sho lapses of awareness with eyelid fluttering that occur every 5-10 minutes. EEG studies reveal brief 3 Hz spike and wave discharges appearing synchronously in all the leads. Which of the following drugs would be effective but has the disadvantage that it causes sedation and tolerance?
Diagnosis of the patient is petit mal epilepsy (absence seizures). Drugs effective against absence seizures are: Ethosuximide Valproate Clonazepam Lamotrigine Clonazepam is a benzodiazepine that can cause sedation and tolerance. Thedrug of choicefor childhood absence seizures (in India) issodium valproate.
Diazepam
Ethosuximide
Clonazepam
Valproic acid
CNS