In a patient suspected to be diagnosed with Rabies, a sample of corneal smear was taken. Which of the following investigations can be done from the specimen?
Ans. (b) Immunofluorescence test style="font-size: 1.04761904761905em; font-family: Times New Roman, Times, serif">(Ref: )Lab diagnosis of rabies*RT-PCR: detecting the viral nucleic acid especially on biological fluids (saliva, cerebrospinal fluid, tears) and skin biopsy (ante mortem) and brain samples (post mortem)*Serum and spinal fluid are tested for antibodies to rabies virus*Skin biopsy specimens are examined for rabies antigen in the cutaneous nerves at the base of hair follicles*Immunofluorescent antibody staining of the epithelial cells on the corneal impression test (FAT)
RT PCR
Immunofluorescence test
Negri body visualization
Virus isolation
Central Nervous System