A hospital nurse is taking Imipramine for a phobic anxiety disorder, and her patient is being treated with chlorpromazine for a psychotic disorder. Which of the following adverse effect is likely to occur in both of them?
Imipramine belongs to Tricyclic antidepressants which have these side effects, such as ohostatic hypotension, drowsiness, cardiac conduction delay, memory impairment, constipation, and urinary retention.Chlorpromazine belongs to Dopamine receptor antagonists, which is more sedating and anticholinergic and more likely to cause ohostatic hypotension.They both have alpha-blocking activity which results in ohostatic hypotension.Reference: Harrison&;s Principles of Internal Medicine; 19th edition; Chapter 466; Mental disorders
Excessive salivation
Pupillary constriction
Ohostatic hypotension
Seizure
Central Nervous system