dihydroerigotamine differs from ergotamine in the following respect
hydrogenation of ergot alkaloids decrease their vasoconstrictor action and increase the Alpha blocking activity Ref-KDT 6/e p168
It is more potent oxytocic
it has antimetic propey
it has high oral bioavailability
it is more potent alpha adrenergic blocker and less potent vasoconstrictor
Other topics and Adverse effects