True about sickle anemia is -
Answer- B. Decreased ESRInvestigations in sickle cell anemia-Peripheral smear shows sickle cells, target cell and Howell - Jolly bodies.ESR is decreasedPositive sickling testHb electrophoresis shows two bands in heterozygous state/sickle cell trait.Bone changes on X-ray show:-A. Fish mouth veebraeB. Crew hair cut (hair on end) appearance of skull.('Hair on end appearance' is also seen in thalassemia, hereditaty spherocytosis and G6PD deficiency.)Gamma Gandy bodies
Leucopenia
Decreased ESR
Microcardia
Ringed sideroblast