All the following are features of Pick's disease except:(2004)
Ans: d (Hirano bodies)Ref: Robbin's, 7thed, p. 1390 & 6th ed, p. 1333Pick's disease-* Asymmetric atrophy of frontal and temporal lobes with conspicuous sparing of posterior two thirds of temporal lobe.* The atrophy can be severe, reducing the gyri to a thin wafer (Knife edge appearance)* Ballooning degeneration of neurons (Harsh mohan, 5th ed, p. 911)* Presence of pick bodies in neurons.* Absence of plaques and neurofibrillary tangles.
Knife blade atrophy
Walnut brain
Ballooning degeneration
Hirano bodies
Central Nervous System