A 2 years old child without fever develps bone pain, vomiting and features of increased intracranial pressure following excessive medication. The drug most likely to be responsible for this is?
Ans. is 'a' i.e., Vitamin A Hvpervitaminosis A o Excess of vitamin A can lead to rupture of lysosomal membrane. o Acute manifestations --> Signs and symptoms are due to raised intracranial tension (pseudotumor cerebri) --> headache, nausea, vomiting, drowsiness, bulging fontanelles, diplopia, papilledema and cranial nerve palsies. o Chronic intoxication --> Anorexia, weight loss, painful extremities, dry itchy desquamating skin, alopecia, coarsening of hair, hepatosplenomegaly, bone abnormalities and bony swelling.
Vitamin A
Phenothiazine
Phenytoin
'Vitamin D