Acquired nasolacrimal duct obstruction is caused by:
Drugs such as epinephrine, echothiopate and pilocarpine can produce lacrimal duct obstruction. Secondary causes of nasolacrimal duct obstruction includes: Traumatic nasal injury with bony fractures, iatrogenic causes such as complications from sinus surgery or orbital decompression, migration of punctual and lacrimal plugs, Sarcoidosis, Wegners granulomatosis, Steven Johnson syndrome and severe nasal polyposis.
Brimonidine
Dorzolamide
Timolol
Pilocarpine