In the investigation of a patient with suspected essential thrombocythaemia, in which of the following genes may you find abnormalities?
All of these mutated genes are associated with haematological conditions : BCR with chronic myeloid leukaemia (CML), c-MYC and BCL-2 with lymphoma, and MYH-9 with congenital thrombocytopathy. Only CAL-R, calreticulin, is associated with the myeloproliferative neoplasm essential thrombocythaemia.
BCL-2
BCR
c-MYC
CAL-R