Which of the following drug inhibits plasminogen activation : March 2009
Ans.B: Tranexaemic Acid Tranexaemic acid is an antifibrinolytic that competitively inhibits the activation of plasminogen to plasmin, a molecule responsible for the degradation of fibrin. It has roughly 7 times the antifibrinolytic activity of an older analogue, Epsilon-amino-caproic acid (EACA). Main side-effects are nausea and diarrhea.headache, giddiness and thrombophlebitis of injected vein are other adverse effects.
Aspirin
Tranexaemic acid
Alteplase
Streptokinase