Isoniazide is metabolized by -
Ans. is 'a' i.e., Acetylation o Isoniazid is extensively metabolized in liver most important pathway being N - acetylation by NAT 2. The acetylated metabolite is excreted in urine.Drugs metabolized bv acetylationo Sulfonamides (including dapson)o INHo Procainamideo Hydralazineo PASo Clonazepam {given in 6th/e)
Acetylation
Oxidation
Reduction
Hydrolysis
Pharmacokinetics