All the following are features of Alzheimer's disease except:
In Alzheimer's, the disease process usually spares cerebellum. Especially neurofibrillary tangles are never seen in cerebellum. Alzheimer's D/s (Dementia of Alzheimer type) Pathophysiological Findings: Diffuse atrophy, Flattened Coical Sulci & Dilated Cerebral ventricles Primarily involve Parietal and temporal Lobes Atrophy stas In Medical Temporal Lobe (Entorhinal/Perirhinal Coex & Hippocampus) and spreads to Lateral & Medial parietal Lobes, Lateral Temporal Lobes & Lateral Frontal Coex
Cerebellar atrophy
Common in 5th and 6th decade
Atrophied gyri widened sulci
Progressive dementia
Organic Mental Disorders