The risk of developing infective endocarditis is the least in patient with -
Ans. is 'd' i.e., Large ASD Pathogenesis of infective endocarditis (IE) Infective endocarditis may develop on previously normal valve, but a variety of cardiac and vascular abnormalities predispose to infective endocarditis. o Two most common cardiac abnormalities that predispose to infective endocarditis are - 1.Rheumatic carditis o Rheumatic carditis causes damage to hea valve. o Damaged pa of hea may be covered with platelets and fibrin, upon which bacteria can take hold. 2. Congenital hea diseases (CHDs) o IE occurs in CHDs where blood flow occurs due to high pressure gradient, e.g. VSD or AS. o The high pressure of jet of blood hits the endocardium and damages it. o Infection generally stas at this lesion. High Risk Moderate Risk Low Risk Prosthetic hea valve MVP + M. R. Mitral valve prolapse without mitral Regurgitation. Tetralogy of fallot T.S. ASD PDA AR P.S. AS M.S. Coarctation of Aoa VSD MR
Small VSD
Severe aoic regurgitation
Severe mitral regurgitation
Large ASD