Beta-glucosidase is defective in which disease?
Ans. a (Gaucher's disease). (Ref: Harper, Biochemistry, 25th ed., 267)Sphingolipidoses DiseaseInheritanceEnzymeCNS involvementVisceral involvement1FabryXLRAlpha-galactosidase-+2Krabbe'sARBeta-galactosidase+(bilateral thalami)+3FarberARCeramidase+/--4GaucherARBeta-Glucosidase+/-+5MetachromaticleukodystrophyARAryl sulfatase+ (Diffuse White matter)-6Niemann-PickARSphigomyelinase++7Tay-SachsARHexosaminidase A+-8SandhoffARHexosaminidase A, B++
Gaucher's disease
Tay-Sachs disease
Galactosaemia
DM
Carbohydrates