Biotin is used in the treatment of:
Multiple carboxylase/biotinidase deficiency:- autosomal recessive disorder due to defect in holocarboxylase synthase or biotinidase deficiency. Clinical features:- -Metabolic ketoacidosis -Diffuse rash -Alopecia -Seizures -Intellectual disability
Multiple carboxylase deficiency
Keto acid dehydrogenase deficiency
Transketolase deficiency
Multiple dehydrogenase deficiency
Vitamins and Minerals