Mechanism of action of Aspirin
Ans. (b) Inhibit TXA2 formationRef KDT 6th ed. / 609; Katzung 9th ed. / 446Thromboxane helps in platelet aggregation.* TXA2 formation is suppressed at very low doses of aspirin.* Aspirin blocks thromboxane formation by inhibiting COX activity by enzyme COX1 and TX- synthase irreversibly.
Inhibit PGI2 formation
Inhibit TXA2 formation
Stimulate TXA2 formation
Stimulate platelet aggregation
Antiplatelets and Fibrinolytics