Tropical Splenomegaly is characterized by all the following, except ________
Tropical splenomegaly "Big spleen disease"found in adults in ceain hyper endemic malarial areas has been shown to be related to an abnormal immune response to plasmodial antigen features hepatomegaly anemia leucopenia massive splenomegaly increased serum IgM concentrations. continuous malaria chemoprophylaxis over many months cause a gradual reduction in the spleen size and clinical improvement Ref : PARASITOLOGY, K.D.CHATTERJEE,13 TH edition, Pg no:117
Persistent high grade fever
Moderate to massive splenomegaly
Residence in areas endemic for Malaria
Clinical response to antimalarials
Gastrointestinal tract