The anti-inflammatory mediator is?
IL-4 has mainly anti-inflammatory property with some proinflammatory action. Proinflammatory cytokines
i) Major:- IL-1, TNF- alpha, IL-6
ii) Other:- IL-2, IL-4, IL-5, IL-6, IL-8, IL-11, IL-12, IL-15, IL-21, IL-23, IFN-gamma, GM-CSF 
Anti-inflammatory cytokines
i) IL-4, IL-10, IL-13, and transforming growth factor β (TGF-β)
Interleukin 4
Interleukin 1
Interleukin 6
TNF- Alpha