A parent noted an abdominal mass in it. the side of her 6 mth. old child. Which showed calcification near the left kidney. what will be the cause
Neuroblastoma is the most common solid tumor of infancy and childhood* and 3/4 of pt present with an abdominal mass. Plain x-ray shows fine, stippled calcification in 50 percent of the cases. More about Neuroblastoma Neuroblastoma is a malignant tumor of neural crest origin*, arising from the sympathetic nervous tissue from the orbit to the pelvis. Age - It occurs chiefly in very young children median age is 2 years. It is the most common solid tumor of infancy and most common tumor in newborn. * MC intrabdominal tumor in children. M.C. site is----- Adrenal medulla* 90% of pts. have increased catecholamine * secretion which can be identified by increased urinary levels of metanephrine and vanillylmandelic acid. Clinical evidence of catecholamine excess is however rare. Excessive VIP secretion presents with Hypokalemic watery diarrhoea * syndrome. Hematogenous metastasis occurs very early. Orbital metastasis* may present with proptosis, periorbital ecchymosis. Ref : Bailey & Love 25/e p814
Neuroblastoma
Leukemia
Renal cell carcinoma
Lymphoma
Endocrinology and breast