A 5-yr-old boy presents with pubic hair development. He is tall and has increased pigmentation of his genitalia and phallic enlargement. Blood pressure is 130/90 mm Hg. Measurement of which of the following hormones would be most likely to be diagnostic?
Presence of Precocious pubey in a male child and hypeension (BP of 130/80 in a 5 year old child is considered hypeension) suggests a diagnosis of congenital adrenal hyperplasia due to 17a- Hydroxylase deficiency. In this condition there is decreased synthesis of both coisol and sex steroids with a resultant increase in secretion of mineralocoicoid (Deoxycoisol).
Increase 17a-Hydroxyprogesterone
Increase Coisol
Increase aldosterone
Increase 11 deoxycoisol