Which of the following is the mechanism of action of tetanospasmin ?
Ans. is 'a' i.e., Inhibition of release of GABA and glycine Pathogenicity CL tetani has little invasive propey and is confined to the primary site of lodgment. Tetanus results from the action of the potent exotoxin it produces.
Inhibition of release of GABA and glycine
Inhibition of Ach release from synapse
Inhibition of protein synthesis
Activation of adenylyl cyclase