Which of the following intravenous anaesthetic agent pharmacokinetic does not change on renal and hepatic dysfunction -
Propofol is metabolized by liver and kidney mainly. but its metabolism exceeds hepatic blood flow, thus having extrahepatic and renal route as well. in liver and kidney dysfuction its metabolism is not delayed making its use safe.
Propofol
Thiopentone
Etomidate
Ketamine
Intravenous Anesthetic Agents