True statement about cyclooxygenase-2 is
Ref-KDT 6/e p185 COX-1 is a house-keeping enzvme that is responsible for the generation of gastroprotective PGs. COX-2 is an inducible enzyme whose production is markedly increased at inflammatory sites. Indomethacin is a non-selective inhibitor of both isoforms of COX.
It Is not inhibited by indomethacin
It I'd inducible
It generate cytoprotective prostaglandins in gastric mucosa
It is found only in fatal tissues
Other topics and Adverse effects