All of the following statements about trientine use in Wilson's disease are true except:
*Penicillamine is the most potent chelating agent useful in Wilson's disease. *Trientine is not as potent as penicillamine and was used in patients unable to tolerate penicillamine.However,now a days, trientine is preferred because of severe adverse effects of penicillamine. *Trientine cause fewer adverse effects other than mild anemia due to iron deficiency in few patients. Ref: KATZUNG 14TH ED.
It is more potent than penicillamine.
It is used as an alternative to penicillamine in non-tolerant patients
It should not be administered with in two hours of iron supplementation
It can cause iron def anemia which is reversible by oral iron supplements
Central Nervous system