What is the mechanism of action of levetiracetam?
Levetiracetam is an anti-epileptic drug that works by binding to SV2A, a ubiquitous synaptic vesicle integral membrane protein, which functions as a positive effector of synaptic vesicle exocytosis. Binding to SV2A in the vesicle reduces the release of the excitatory neurotransmitter glutamate. It is used for treatment of focal seizures GTCS, JME
Antagonist of GABAA receptor
Bind to synaptic vesicular protein SV2A
Inhibit voltage gated Ca+ channel
Inhibit Na+ channel
Epilepsy