Which of the following enzyme deficiency is the most common cause of pseudohermaphroditism in a female child?
Most common cause of female pseudohermaphroditism is congenital adrenal hyperplasia mostly caused by deficiency of the enzyme 21 hydroxylase. Due to this enzyme deficiency, there is deficient production of adrenal coisol and aldosterone and overproduction of adrenal androgens.
3 - hydroxylase deficiency
11 - hydroxylase deficiency
17 - hydroxylase deficiency
21- hydroxylase deficiency