False about Barret's Esophagus is:
Answer is D (None): All statements about Barret's Esophagus are true Stricture in Barret's esophagus may present in high oesophagus Barret's oesophagus can also lead to chronic peptic ulcers of the esophagus with high and long strictures. Barret's esophagus is premalignant Barret's esophagus can progress to adenocarcinoma Diagnosis can be suggested by Endoscopy Endoscopy shows a 'salmon pink' epithelium above the gastroesophageal junction which replaces the whitish squamous epithelium. Diagnosis is confirmed by biopsy Diagnosis is confirmed by pathological examination and requires the identification of columnar (intestinal) type epithelium characterized by the presence of goblet cells. Barret's Esophagus Metaplasia of esophageal squamous epithelium into columnar in distal oesophagus Most common type of columnar epithelium is intestinal epithelium (intestinal metaplasia)U Metaplasia characteristically affects the distal (lower) oesophagus It is consequence of severe reflex esophagitisU More common in menu (Males > Females) More common in whites (Whites > Blacks) More common with increasing age (incidence increases with age) Considered a premalignant condition Type of cancer associated in an adenocarcinoma Columnar metaplasia that carries maximum risk of adenocarcinoma is intestinal metaplasia (intestinal epithelium)U Can lead to chronic peptic ulceration of esophagus (Barret ulcer) Can lead to high (midoesophageal) and long strictures
Premalignant conditions
Can be diagnosed by seeing under endoscope
Biopsy is necessary to confirm diagnosis
None