Non specific esterase is positive in all the categories of AML except
Non specific esterase on cytochemistry is strongly positive in M5(acute monocytic leukemia- Schilling type) and M4(acute myelomonocytic leukemia -Naegeli type) which have monocytic component.It is also positive in M3(acute promyelocytic leukemia).But non specific esterase is negative in M6(acute erythroleukemia-Di Guglielmo's syndrome),which shows positive for Periodic acid-Schiff. Reference:Textbook of pathology-Harsh Mohan,6th edition,page no:362.
M3
M4
M5
M6
Childhood tumors