A patient presented with oral mucosal lesions and flaccid blisters Over skin. It detects what and which pattern under microscopic examination?
In pemphigus vulgaris skin involvement stas in the form of flaccid blisters. Cutaneous lesions are usually preceded by blisters and erosions of oral mucosa In Direct immunofluorescence intercellular IgG -fishnet pattern throughout the epidermis is seen in pemphigus vulgaris. page no.280,287 Reference IADVL's concise textbook of dermatology
Fishnet pattern IgG in epidermis
IgG at Dermo-epiderrnal juction
IgA at Dermo-epidermal junction
IgG in dermis
Vestibulobullous disorders