A 15 year old child has developed dystonia and poor school grades. Slit examination is shown below. Which is the initial investigation recommended for the patient ?
KF Ring can be seen in the image which is seen in Wilson disease Screening test:- 24 hours urinary copper Conformational:- Biopsy. Rx: Trientine- copper chelator Penicillamine- also chelator but less used due to nephrotic side effect. Zinc- is competitive inhibitor of copper in absorption of gut. Zinc acetateisDOCfor Wilson disease.
Serum ceruloplasmin
Serum copper
24 hour urinary copper
Liver biopsy
Liver