Concerning fibroids:
Option a: Incorrect as regrowth of myoma occurs after 3 months of GnRH therapy
Option b: Is also incorrect as pregnancy rate following myomectomy is 50–60% and not 30%.
Option c: Recurrence rate is 1%, 10% and not 30% hence it is also incorrect.
Option d: “Epidermal growth factor (EGF), insulin like growth factor (IGF 1), transforming growth factor (TGF), stimulate the growth of the leiomyoma either directly on via estrogen” Dutta Gynae 6th/ed p 272. Hence option d is correct.
Use of GnRH analogues cause permanent reduction in size
Pregnancy following myomectomy is about 80%
Recurrence rate following myomectomy is about 30%
Growth factors (IGF-1, EGF) stimulates myoma to grow