Gluten sensitive enteropathy is strongly associated with:
Gluten enteropathy/Celiac Sprue It is associated with HLA -DQ2 Due to auto Ab against brush border epithelium which is present in the gut mucosa Clinical Feature-Osmotic diarrhoea Auto ab: Anti tissue transglutaminase Ab - Screening test Small intestinal mucosal Biopsy - Confirmatory test Treatment: No 'BROW'(Barley, Rye, Oats, Wheat) Only maize is allowed
Blood group B
HLA-DQ3
HLA-DR4
HLA-DQ2
Malabsorbtion Syndrome