Which finding on electron microscopy indicates irreversible cell injury-
Ans. is 'c' i.e., Flocculent densities in mitochondria Mechanism of irreversible cell injury :? Membrane damage is the central factor in the pathogensis of irreversible cell injury. Note : o Earliest change of reversible cell injury is cellular swelling. o Myelin figures (laminated structure) derived from damaged membrane of organelles and plasma membrane, first appear during reversible injury, but become more pronounced in irreversible injury.
Dilatation of endoplasmic reticulum
Dissociation of ribosomes from rough endoplasmic reticulum
Flocculent amorphous densities in the mitochondria
Myelin figures