Which of the following statements regarding drugs used in Leprosy is false
Ref-KDT 6/e p752,753 Acedapsone is a repository form of dapsone. Single i.m. injection of acedapsone keep on releasing the drug for 3 months. Rifampicin is used once in a month (supervised dose) for the treatment of leprosy. It prevents the emergence of resistance to dapsone. Clofazimine can result in skin pigmentation, discolouration ofsecretions and dryness of skin (icthyosis). Clofazimine has no cross-allergenicity with dapsone.
Single intramuscular injections of acedapsone maintain inhibitory levels of dapsone in tissues for up to 3 months
Monthly doses of rifampicin delay the emergency of resistance to dapsone
Clofazimine should not be given to patients who are intolerant to dapsone or who fail to improve during treatment with dapsone
Clofazimine may cause changes in skin colour
Other topics and Adverse effects