Which of the following is not an established antimicrobial drug synergism at clinical level?
Combination of a bacteriostatic and a bactericidal drug in most cases is antagonistic. Bactericidal drugs act on fast multiplying organisms whereas bacteriostatic drugs inhibit the growth. Here, penicillins are bactericidal whereas tetracyclines are bacteriostatic.
Amphotericin B and flucytosine in cryptococcal meningitis
Carbenicillin and gentamicin in pseudomonal infections
Penicillin and tetracycline in bacterial meningitis
Trimethoprim and sulfamethoxazole in coliform infections
Cell Wall Synthesis Inhibitors