All of the following are major criteria for diagnosing Myeloma except?
Major criteria for diagnosing myeloma includes presence of plasmacytoma on tissue biopsy, bone marrow plasmacytosis (more than 30%), and serum electrophoresis showing monoclonal immunoglobulin spike. Presence of lytic bone lesions is a minor criteria for diagnosing myeloma. Ref: The Washingtom Manual Of Surgical Pathology: Depament Of Pathology , By Peter A Humphrey, Loius P.Dehner, Ohn D. Pfeifer, Page 565.
Tissue biopsy suggestive of myeloma
Bone marrow plasma cells > 30 %
IgG level > 35 g/l
Lytic bone lesions in X-ray