Regan isoenzyme is increased in
The Regan isoenzyme is a placental-type alkaline phosphatase that is expressed in a number of human tumors, paicularly in gonadal and urologic cancers. Evidence now points to seminoma as a consistent producer of Regan isoenzyme although much more work will be required to establish its clinical utility. Ref:
Seminoma
Paget's disease
Osteoporosis
Cholestasis
Enzymes