The most frequently implicated antibiotic among the causes of drug induced liver injury is:
Amoxicillin-clavulanic acid : The most frequently implicated antibiotic among cases of drug-induced liver injury. Reference: Harrisons Principles of Internal Medicine, 18th Edition, Page 2560
Tetracycline
Amoxicillin-clavulanic acid
Erythromycin
Nalidixic acid