Primary hyperaldosteronism what is seen
The clinical hallmark of mineralocoicoid excess is hypokalemic hypeension Due to excess mineralocoicoid action lead to potassium and H+ depletion sodiu retention Serum sodium tends to normal due to concurrent fluid retention Because of h+ depletion lead to metabolic alkalosis Clinical features: 1) hypokalemia 2) hypeension at young age generally <40 3) metabolic alkalosis 4)muscle cramps in severe case tetany due to metabolic alkalosis
Hyperkalemia
Hyponatremia
Maetabolic alkolosis
Fall in aldosterone with sodium loading
Endocrinology