Lafora's disease presents with?
Lafora's disease - It is a progressive myoclonic epilepsy with AR inheritance. -Onset: 6-19 years -Death within 10 years -Brain degeneration a/w polyglucosan intracellular inclusion bodies in numerous organs. - IOC: DNA sequencing which shows abnormality in EPM2A and EPM2B gene. -Demonstration of Lafora bodies within the apocrine sweat gland of the skin is seen by an axillary skin biopsy examination. -Rx: Zonisamide
G.T.C.S
Myoclonic epilepsy
Petit mal epilepsy
Paial seizures
Epilepsy and EEG