gordons syndrome is charecterized by by al except ?
* Type II pseudohypoaldosteronism in adults with HT( Gordon&;s syndrome ) .primary defect may be related to "enhanced Cl reabsorption in early distal tubule".../imit Na delivery to more distal tubule, decreased lumen negativity, impaired K secretion due to voltage-shunt effect -- Increased NaC1 reabsorption expand ECF volume...HT and suppress RAAS -- Hyper K contributes to inhibition of renin secretion -- PA..normal or suppressed depending upon balance between inhibitory effect of volume expansion and stimulatory effect of hyperkalemia harrisons 21st ed
hyperkalemia
metabolic acidosis
low rennin and low aldosterone
hypotension
All India exam