Malignant hypehermia is caused due to which of the following mechanism?
The mechanism involves a sudden rise in intracellular calcium due to release of stored calcium in sarcoplasmic reticulum, stimulating contraction, rhabdomyolysis and a hypermetabolic state.(Refer: stoelting's pharmacology and physiology in anaesthetic practice, 5th edition, pg no.823)
Increased intracellular NA
Decreased intracellular chlorine
Increased intracellular Ca
Increased serum K
All India exam