In Gaucher&;s disease, there is a deficiency of
Due to deficiency of glucocerebrosidase, causes glucosylceramide accumulation in macrophages called Gaucher&;s cells.DiseaseEnzyme DeficiencyClinical SymptomsGaucher diseaseb-GlucosidaseEnlarged liver and spleen, erosion of long bones,mental retardation in infantsRef: Harper&;s biochemistry; 30th edition; Chapter 24 Metabolism of Acylglycerols & Sphingolipids
Glucocerebrosides
glucokinase
Sphingomyelinase
G-6PD
Structure and function of protein