Which of the following condition is related with antibodies against phenolic glycolipid (PGL-1)?
The bacterium's complex cell wall contains large amounts of an M. leprae-specific phenolic glycolipid (PGL-1), which is detected in serologic tests. The unique trisaccharide of M. leprae binds to the basal lamina of Schwann cells; this interaction is probably relevant to the fact that M. leprae is the only bacterium to invade peripheral nerves. IgM antibodies to PGL-1 are found in 95% of patients with untreated lepromatous leprosy. Ref: Gelber R.H. (2012). Chapter 166. Leprosy. In D.L. Longo, A.S. Fauci, D.L. Kasper, S.L. Hauser, J.L. Jameson, J. Loscalzo (Eds), Harrison's Principles of Internal Medicine, 18e.
M. leprae
M. tuberculosis
Borrelia
Brucella