A 30-year-old female complaints of fatigue and is unable to gain weight. On examination, her body felt warm. Which of the following investigation can be helpful in reaching the diagnosis?
On the basis of above clinical scenario patient is suffering fromprimary Hypehyroidism. Primary Hypehyroidism CLINICAL FEATURES: Sympathomimetic stimulation : Palpitations - beta1 activation Fine Tremors - beta 2 activation Sweat on palms/soles Hypeension - alpha1 activation 2. BMR | -Weight loss 3. Calorigenesis | - Heat intolerance 4. Females - Oligomenorrhea / Infeility 5. Proptosis - Blinking action is inadequate - Drying of cornea - Exposure Keratitis - Grittiness / sand like sensation in eye. Work-UP: Thyroid Function Tests - Total T4 & T3- |, Free T4, T3 -| TSH: - If low - Primary hypehyroidism Fuher investigations are: LATS titre Thyroid scan USG Abdomen - If high - Secondary hypehyroidism - pituitary adenoma - Dx MRI head
High TSH with normal T3, T4
Low TSH with high T3, T4
High TSH with euthyroid status
Increased uptake of T3, decreased level of T4
NEET Jan 2020