Hepatitis with cholestatic jaundice occurs most frequently as an adverse reaction to the following preparation of erythromycin:
Erythromycin estolate is responsible for cholestatic jaundice. It stas after 2-3 weeks of staing treatment. Symptoms include nausea, vomiting and cramping pain in abdomen. Risk of this adverse effect increases significantly in pregnancy. Therefore, erythromycin estolate is contra-indicated in pregnancy.
Erythromycin base
Erythromycin stearate
Erythromycin estolate
Erythromycin ethyl succinate
Protein Synthesis Inhibitors