A 57-year-old patient, living at home, has severe pain due to a metastatic Carcinoma that is being managed with Fentanyl, delivered transdermally from a patch. He should also be taking, or at least have on hand
Constipation caused by Fentanyl could be treated by a laxative like docusate. As Fentanyl has equivalent effects like Morphine, an addition of Morphine might cause toxicity. Fentanyl causes vomiting so the addition of an emetic like Apomorphine would be counterproductive. Naloxone is an antagonist to opioid analgesics
Apomorphine
Docusate
Morphine
Naloxone
Gastrointestinal tract