Which of the following is the ratelimiting enzyme in the biosynthesis of catecholamines?
Tyrosine hydroxylase is the rate-limiting enzyme in the biosynthesis of catecholamines. Tyrosine is first hydroxylated to form 3,4- dihydroxyphenylalanine (DOPA) by the enzyme tyrosine hydroxylase. This enzyme is abundant in the central nervous system, the sympathetic ganglia, and the adrenal medulla Reference: Harpers illustrated biochemistry 30th edition
Dopamine hydroxylase
Tyrosinase
DOPA decarboxylase
Tyrosine hydroxylase
Metabolism of protein and amino acid