Norepinephrine to epinephrine conversion requires which enzyme:
Ans:A.)Phenylethanolamine-N-methyltransferaseMethylation of norepinephrine by S-adenosyl-methionine gives epinephrine, reaction being catalysed by phenylethanolamine N-methyltransferase Phenylethanolamine N-methyltransferase (PNMT)It is an enzyme found in the adrenal medulla that conves Norepinephrine (Noradrenaline) to Epinephrine (Adrenaline).PNMT is positively influenced by coisol, which is produced in the adrenal coex.S-adenosyl-L-methionine ('SAM') is a required cofactor.
Phenylethanolamine-N-methyltransferase
Transaldolase
Tyrosine hydroxylase
Alpha ketoglutarate