The pathognomonic feature of classic alpo syndrome is:
The diagnosis of classic alpo syndrome is based on X-linked inheritance of hematuria, sensorineural hearing loss, and lenticonus. The lenticonus together with hematuria is pathognomonic of classic Alpo syndrome. Reference: Harrisons Principles of Internal Medicine, 18th Edition, Pages 3213-14
Lenticonus and hematuria
Hematuria and sensorineural hearing loss
Sensorineural hearing loss and lenticonus
Hematuria and hyperextensibility of joints