"Onion skin" fibrosis of bile duct is seen in -
Ans (b) Primary sclerosing cholangitisRef: Robbings pathology 9th ed. I860PRIMARY SCLEROSING CHOLANGITIS* Leads to obstructive jaundice leading to elevation of serum transaminases, gamma glutamyl transferase and alkaline phosphatase* Typical onion skin fibrosis of bile ducts* Per-cutaneous transhepatic cholangiography demonstrates irregularity and beading of the hepatic and common bile ducts in three patients.# Onion skin appearance in kidney seen in hyperplastic arteriosclerosis# Onion skin like lesions due to arteritis seen in Lymes and SLE# Onion skin fibrosis around bile ducts seen in PSC# Onion skin pattern of deposition of reactive bone in ewing s sarcoma# Onion bulb appearance in sural nerves seen in CIDP due to recurrent demyelination and remyelination
Primary biliary cirrhosis
Primary sclerosing cholangitis
Extrahepatic biliary fibrosis
Congenital hepatic fibrosis
Disorders of Gallbladder and Extrahepatic Biliary Tract