Local anaesthetics acts by inhibiting: March 2012
Ans: A i.e. Sodium channels Local anaesthetics act by inhibiting sodium channels from inside Local anesthetics Generally blocks: Sodium channels Potency of LA depends on: Lipid solubility Susceptibility of fibres to LA: Type B > type C > type A Amide linked LA: - Lidocaine, - Bupivacaine etc. Ester linked LA: - Cocaine,
Sodium channels
Potassium channels
Calcium channels
Magnesium channels