Thrombomodulin-thrombin complex produces its anticoagulant effect by-
Thrombomodulin Present on the endothelial cells and binds to thrombin and activates protein C, which inhibits clotting by proteolysis of factor Va and VIIIa. Ref: RAM DAS NAYAK 2nd Ed. Pg 89
Inactivating factor V and VIII
Inactivating protein C
Inactivating protein S
Inactivating factor VIII
miscellaneous