A7 year old presents with fever, weight loss. On examination he was pale and had significant lymphadenopathy. Bone marrow histology is as given below. What is the most probable diagnosis?
Ans. (a) ALL(Ref: R 9/611)The picture is that of a lymphoblast. Lymphoblasts will be 3-4x larger than a mature RBC, High nuclear to cytoplasmic ratio, Round Nucleus with immature chromatin (not clumped), Prominent nucleoli, Cytoplasm is scant, light blue and lacks granules
ALL
AML
Aplastic anaemia
juvenile myelomonocyticleukemia
Misc. (W.B.C)