True statement about gall stones are All/EXCEPT:
Ans. is 'd' ie. More common in males between 30-40 yrs. of age Ref. Bailey & love, 25/e pll20 (24/e p. 1103, 23/e, p 974)Though Cholelithiasis can occur in both sexes from childhood to the centenarian (people in their 100), it is more common in females. A fat, fertile, flatulent, female of fifty' is the clinical sufferer from symptomatic gallstones.Lithogenic bile : is required for the formation of mixed stone and cholesterol stones.Bile contain cholesterol, insoluble in water and held in solution by detergent action of bile salts & phospholipids. When there is excess of cholesterol relative to bile salts & phospholipids, cholesterol gets precipitated to form gall stones. Such a bile is termed supersaturated or lithogenic." Diabetes mellitus can cause increased incidence of cholesterol gallstones, probably related to increased cholestrol level in bile." - Chandrasoma Taylor, 3/e, p 666.Gall stones are associated with Ca gall bladder. In over 90% cases gall stones are found associated with Ca G.B.
Lithogenic bile is required for stone formation
May be associated with carcinoma gall bladder
Associated with diabetes mellitus
More common in males between 30 - 40 years of age
Gallstone Disease