All are poor prognostic for multiple myeloma except
A - Commonest mutation associated with multiple myeloma is 13q deletion. Poor prognostic factor associated with multiple myeloma are: 1. t (14 16) 2. 1q gain 3. 3.t (4 14) Risk Stratification in Myeloma CHROMOSOMAL ABNORMALITIES Method Standard Risk (80%) (Expected Survival 6-7+ Years) High Risk (20%)(Expected Survival 2-3 Years) Karyotype No chromosomal aberration Any abnormality on conventional karyotype Fish t (11:14) t(6:14) Del(13) Del (17p) t(4:14) t(14:16) t(14:20 amp 1q34
t (11 14)
t (14 16)
1q gain
t (4 14)
JIPMER 2018