Interleukin secreted by macrophages, stimulating lymphocytes is -
Interleukin -I o Also known as leucocyte activating factor (LAF) or B cell activating factor (BAF). Mainly secreted by macrophages and monocytes; and epithelial cells. Other sources are B-lymphocytes, fibroblasts and Endothelial cells. o Immunological effects of IL-1 Activation of T cells for the production of IL - 2. B cell proliferation and antibody synthesis Neutrophil chemotaxis and increased PMN release from bone marrow. Increases body temperature (impoant endogenous pyrogen). Bone marrow cell proliferation Induction of acute phase protein.
INF alpha
TNF alpha
IL-1
IL-6