Enzyme inhibited by insulin is
3. Hypoglycemic Effect of INSULINE - i. Insulin lowers the blood glucose level by promoting utilization and storage. ii. Gluconeogenesis is inhibited by insulin by repressing the key enzymes, pyruvate carboxylase (PC) phosphoenol pyruvate carboxykinase (PEPCK) and glucose-6- phosphatase. iii. Insulin inhibits glycogenolysis by oring the inactivation of glycogen phosphorylase and inhibiting glucose-6-phosphatase. The net effect of all these three mechanisms, blood glucose level is lowered. REF: DM VASUDEVAN TEXTBOOK OF BIOCHEMISTRY, EIGHTH EDITION,PG.NO.,167.
Glucokinase
PFK-1
Glycogen phosphorylase
Glycogen synthase
Metabolism of carbohydrate