In renal disease albumin is first to appear in urine because
Ans. (b) Has molecular weight slightly greater than the molecules normally getting filtered(Ref: Ganong, 25th ed/p.677)Glomerular membrane permits neutral substances up to 4 nm in diameter. Substances greater than 8nm diameter are totally excludedAlbumin size is 7 nm. So, it has molecular weight slightly greater than the molecules normally getting filtered
Of its high concentration in plasma
Has molecular weight slightly greater than the molecules normally getting filtered
High albumin : globulin ratio
Tubular epithelial cells are sensitive to albumin
Kidneys and Body Fluids