Manganese deficiency leads to?
Ans. (b) Impaired skeletal growthRef: Harrison /96e-9* Manganese deficiency leads to impaired growth and skeletal development whereas toxicity leads to parkinsonism like features. Impaired glucose tolerance is seen with chromium deficiency.Deficiencies and Toxicides of MetalsElementDeficiencyToxicityManganeseImpaired growth and skeletal development, reproduction, lipid and carbohydrate metabolism; upper body rashParkinsonism like symptomsEncephalitis-like syndromeCalciumReduced bone mass, osteoporosisRenal insufficiency (milk-alkali syndrome), nephrolithiasisCopperAnemia, growth retardation, defective keratinisation and pigmentation of hair, degenerative changes in aortic elastin, osteopeniaVomiting, diarrhea, hepatic failure, tremor, mental deterioration, haemolytic anemia, renal dysfunctionChromiumImpaired glucose toleranceOccupational: Renal failure, dermatitis,FluorideT Dental cariesDental and skeletal fluorosis, osteosclerosisIodineThyroid enlargement, nF T4, cretinismThyroid dysfunction, acne-like eruptionsSeleniumCardiomyopathy, heart failure, striated muscle degenerationAlopecia, nausea, vomiting, abnormal nails, emotional lability, peripheral neuropathy, lassitude, garlic odor to breath, dermatitisOccupational: Lung and nasal carcinomasZincGrowth retardation, >1 taste and smell, alopecia, dermatitis, diarrhea, immune dysfunction, failure to thrive, congenital malformationsReduced copper absorption, gastritis, sweating, fever, nausea, vomiting
Parkinsonism
Impaired skeletal growth
Impaired glucose tolerance
Anaemia
Environment & Nutritional Pathology