A lady with secondary amenorrhea is negative for progesterone challenge test but positive for combined estrogen and progesterone challenge test. What is the probable cause:-
PCOS has plenty estrogens but no progesterones, hence Progesterone therapy will elicit a withdrawal bleeding Asherman Syndrome is Endometrial Fibrosis, hence no estrogen or progesterone will show any effect In Pregnancy , if Estrogen and progesterones are given, it will not cause a withdrawal since the patient herself is making adequate amount of those hormones. Only ovarian failure or an Hypothalamic failure will be positive for combined estrogen and progesterone challenge test.
Ovarian failure
PCOD
Asherman syndrome
Pregnancy
Normal Menstruation, Abnormal Menstruation, Menopausal Physiology and forsight of conception