Which of the following is the leading cause of GHRH mediated acromegaly?
The leading cause of GHRH mediated acromegaly is chest or abdominal carcinoid tumour. It will present with elevated GH levels and pituitary enlargement on MRI leading to high probability of misdiagnosis as pituitary adenoma. GHRH levels can be used to differentiate a pituitary vs extra pituitary aetiology.
Hypothalamic Hamaoma
Choristoma
Carcinoid tumour
Pluri-hormonal adenoma
Disorders of pituitary gland