A patient treated for infeility with clomiphene citrate presents with sudden onset of abdominal pain and distension with ascites. Most probable diagnosis is:
Ovarian hyperstimulation syndrome (OHSS) is a clinical symptom complex associated with ovarian enlargement resulting from exogenous gonadotropin therapy. Symptoms may include abdominal pain and distension, ascites, gastrointestinal problems, respiratory compromise, oliguria, hemoconcentration, and thromboembolism. Predisposing factors for OHSS include, Multifollicular ovaries such as with PCOS Young age High estradiol levels during ovulation induction Pregnancy Ref: Hoffman B.L., Schorge J.O., Schaffer J.I., Halvorson L.M., Bradshaw K.D.,Cunningham F.G., Calver L.E. (2012). Chapter 20. Treatment of the Infeile Couple. In B.L. Hoffman, J.O. Schorge, J.I. Schaffer, L.M. Halvorson, K.D. Bradshaw, F.G. Cunningham, L.E. Calver (Eds), Williams Gynecology, 2e.
Uterine rupture
Ectopic pregnancy rupture
Multifetal pregnancy
Hyperstimulation syndrome