Mechanism of action of d-tubocurarine is
Depolarizing MR - Succinylcholine | - Shoest acting MR - C/I in nerve and muscle injury because it can cause | K+ - Hypehermia can occur. - It causes fasciculations responsible for post-operative muscle pain. Non - Depolarizing or competitive MR d- Tubocurarine - It releases lot of histamine that leads to vasodilation and bronchoconstriction. It competitively inhibit the Nm receptor.
Competitive, nondepolarizing block at the Nm cholinergic receptor
Non - competitive, nondepolarizing block at the Nm cholinergic receptor
Competitive, depolarizing block at the Nm cholinergic receptor
Noncompetitive, depolarizing block at the Nm cholinergic receptor
Miscellaneous