Necrotizing aerioritis with fibrionoid necrosis is-
Type III hypersensitivity occurs when there is accumulation of immune complexes (antigen-antibody complexes) that have not been adequately cleared by innate immune cells, giving rise to an inflammatory response and attraction of leukocytes. Such reactions progressing to the point of disease produce immune complex diseases.Disease Target antigen Main effects Systemic lupus erythematosus Nuclear antigens Nephritis Skin lesions Ahritis Rheumatoid Ahritis Antibody complexes: specifically IgM to IgG Ahritis Post-streptococcal glomerulonephritis Streptococcal cell wall antigens Nephritis Polyaeritis nodosa Hepatitis B virus surface antigen Systemic vasculitis Reactive ahritis Several bacterial antigens Acute ahritis Serum sickness Various Ahritis Vasculitis Nephritis Ahus reaction Various Cutaneous vasculitis Farmer's Lung Inhaled antigens (often mould or hay dust) Alveolar inflammation Henoch-Schonlein purpura Unknown, likely respiratory pathogen Purpura Glomerulonephritis Ref Robbins 9/e p125
Immediate hypersensitivity
Cell mediated* unity
Antigen-antibody complex mediated
Cytotoxic cell mediated
General pathology