True statements about P53. gene are all except -
Robbins and Cotran pathologic basis of disease South Asia edition. P53 gene located on sho arm of chromosome 17 is also termed TP53 because of molecular weight of 53kd for the protein. P53 inhibits the cyclins and CDKs and prevent the cell to enter G1 phase transiently. .
Arrest cell cycle at G1 Phase
Product is 53 KD protein
Located on chromose 17
Wild\/non-mutated form is associated with in-creased risk of child-hood tumors
General pathology