Tricyclic antidepressant are contraindicated in:
Due to anticholinergic action, TCAs should be avoided in glaucoma These agents block muscarinic acetylcholine receptors, resulting in anticholinergic effects (e.g., dry mouth, blurred vision, urine retention, constipation); they are contraindicated in patients with glaucoma.
Glaucoma
Brain tumor
Bronchial asthma
Hypeension
Mood Disorders