Biopsy from parathyroid gland from a 55-year old male who presented to nephrology department of AIIMS has been shown below. He is a known case of chronic kidney disease with hypertension and type II diabetes. He has recently developed bone pain, lesions in skin and recurrent stones in kidney
Ans. (a) Water clear cells in parathyroid hyperplasia.*The given histology shows abundant optically clear cells of variable size (hyperplasia and hypertrophy), with spherical clear vacuoles surrounded by thin eosinophilic material; basal nuclei, compact or alveolar patterns.
Water clear cells in parathyroid hyperplasia
Water clear cells in parathyroid Ca
TB parathyroid
Parathyroid Necrosis
Endocrine