Which of the following statements about changes in aicular cailage with ageing is not true:
Cailage propey Aging Osteoahritis Hydration Decreased Increased ( in late OA its also decreased) Proteolytic enzymes Normal Increased Proteoglycan content Decreased(due to decreased synthesis) Decreased (due to increased destruction)
Total proteoglycan content is decreased
Synthesis of proteogycans is decreased
Enzymatic degradation of proteoglycans is increased
Total water content of cailage is decreased
Osteochondritis and Avascular Necrosis