Which gene is involved in pathogenesis of Type 1 Diabetes mellitus?
Polymorphism in promoter region of insulin gene, CTLA-4 contributes to susceptibility to type 1 Diabetes mellitus. The most common cause of type 1 diabetes mellitus is autoimmunity. Most patients have DR3 and/ or DR4 haplotype.
CTLA-4
ABCD1
HNF-1 Alpha
HNF-4 Alpha
Diabetes Mellitus