Perivascular lymphocytic and microglial nodules are seen in
HIV encephalitis Chronic inflammatory reaction characterized by widely distributed microglial nodules, often containing macrophage-derived multinucleated giant cells; foci of tissue necrosis . Reactive gliosis are sometimes seen together with these lesions. Microglial nodules found near small blood vessels, show abnormally prominent endothelial cells and perivascular foamy or pigment-laden macrophages.
Multiple sclerosis
HIV encephalitis
Bacterial meningitis
CMV encephalitis
Immunodeficiency Disorders