True about first order kinetics of elimination -
Ans. C. Clearance remains constantFirst order kinetics:Rate of elimination is directly propoional to Plasma Concentration.Clearance remains constant -Due to increasing plasma concentration, increases the rate of elimination propoionately.(CL = rate of elimination / Plasma Conc).Half life remains constant -Due to time required to reduce plasma concentration to half is same (rate of eliminationchange propoionately with plasma concentration).
Constant amount of drug is eliminated
Rate of elimination is not related to plasma concentration
Clearance remains constant
Half life decreases with decreased concentration