Which of the following is required to bring about gluconeogenesis from pyruvate?
Pyruvate in the cytoplasm enters the mitochondria. Then, carboxylation of pyruvate to oxaloacetate is catalysed by a mitochondrial enzyme, pyruvate carboxylase (Fig. 9.24). It needs the co-enzymes biotin and ATP.Ref: DM Vasudevan, 7th edition, page no: 118
Pyruvate dehydrogenase
Biotin
Alpha ketoglutarate dehydrogenase
Fructose-6 phosphate
Metabolism of carbohydrate