Enzyme deficiency in Hurler syndrome?
Disease name Abbretion Enzyme Defective GaG(s) affected Symptoms Hurler syndrome MPS I a-l-Iduronidase Dermatan sulfate, Heparan sulfate Mental retardation, coarse facial features, hepatosplenomegaly, cloudy cornea Reference: Harper; 30th edition; Page no:639; Table: 50-8
Iduronate sulfatase
a-l-Iduronidase
b-Galactosidase
Galactosamine 6-sulfatase
Metabolism of carbohydrate