A child presented with edema, massive proteinuria and hyperlipidemia. True statement about this condition is:
Glomerular barrier function depends on the molecular size (the larger, the less permeable) and charge (the more cationic, the more permeable) is done. The anionic moieties present within the capillary wall including the acidic proteoglycans of the GBM and the sialoglycoproteins of epithelial and endothelial cells are responsible for the viually complete exclusion of albumin (also having anionic charge) from the filtrate.
Type of focal segmental GN
IgA deposition on basement membrane
Foot process of glomerular membrane normal
Glomerular function is lost due to loss of polyanionic charge on both sites of glomerular foot process
Kidney disorders