True about oncogene is
Ref ananthanaraya 7/580 -581, Robbins 7)e p293,302 Viral oncogene which commonly known as cancer gene which encodes protein triggering transformation of Norma cells to cancer cells Proto oncogene are the normal cellular genes that promote normal growth and differentiation Oncogene isolated from cancer cells are called cellular oncogenes Proto oncogenes are conveed to oncogenes and cause cancer by: Transduction of oncogenes by the virus is through recombination of DNA of a host cell that had been infected by the virus,.thus they are host cell origin. The virus acts as tranducting agent, carrying oncogene from one cell to another
Present in normal' cell
They are of viral origin
They arevtranduced from virus infected cells
P53 is most common oncogene mutation causing malignancy
General anatomy