Moderate to high titres of anti-DNA and anti-Smith antibodies are almost pathognomonic of:
Laboratory Findings
Antinuclear antibodies are frequently found in patients with SLE and can be used to indicate a systemic involvement, but patients with other rheumatologic diseases, such as Sjögren’s syndrome and rheumatoid arthritis, may be positive as well. Moderate to high titers of anti-DNA and anti-Smith antibodies are almost pathognomonic of SLE.
SLE
EM
Lichen planus
All of the above