Which of the following antidiabetic drugs can cause vitamin B12 deficiency?
Lactic acidosis (more with phenformin) and megaloblastic anemia (more with metformin) due to vitamin B12 defi­ciency are the major adverse effects of these drugs. Lactic acidosis is more likely to occur in the presence of hepatic and renal impairment or alcohol ingestion.
Glipizide
Acarbose
Metformin
Pioglitazone