What is the treatment of Choice for Idiopathic Thrombocytopenic Purpura?
Ans. (a) SteroidsRef: Surgery Sixer 3rd Edition page 724Medical Treatment of ITP* The treatment of choice is medical- oral prednisolone 1mg/kgproduces dramatic response in 50-70% cases.* Intravenous immunoglobin is indicated for internal bleeding.Refractory ITP* Failure of initial therapy mentioned above.* Rituximab given IV* Thromboplastin Receptor antagonists - Eltrombopag and RomiplostimSplenectomy* Most common indication for elective splenectomy* For patients with low platelet count should have platelets available at surgery but should be infused only after ligating the pedicle.* Should not be given preoperatively
Blood transfusion
Steroids
IV immunoglobin
Splenectomy
Spleen