HER-2/ neu receptor play a role in:
Ans. is 'a' i.e., Predicting therapeutic response o Overexpression of HER-2/neu in breast cancer patients is associated with poor prognosis and increases disease recurrence. o Overexpression HER-2/neu also predicts good response to transtuzumab (Herceptin), a drug approved for HER-2/ neu overexpressing breast cancer. o Because of its prognostic role as well its ability to predict response to transtuzumab (Herceptin), breast cancers are routinely checked for overexpression of HER-2/neu.
Predicting therapeutic response
Determining treatment for recurrence of tumor
Diagnosis of breast Ca
Screening of breast Ca