All are true regarding hyper IgE syndrome except
Ref Robbins 9/e p242 , Harrison 17/e p384;2061;2056;381 Hyper IgE Syndrome (HIES) is a rare primary immunodeficiency disease characterized by eczema, recurrent staphylococcal skin abscesses, recurrent lung infections, eosinophilia (a high number of eosinophils in the blood) and high serum levels of IgE But normal IgG ,IgM,IgA
Inheritance is as a single locus autosomal dominant trait with variable Expression
Coarse facial features
Recurrent staphylococcus abscess involving skin ,lungs
High IgE with low IgG ,IgA,and IgM
General anatomy