A 69-year-old man has lost a friend to prostate cancer, and would like to be evaluated for the disease. He has no urinary symptoms. Which of the following tests is most likely indicated to screen him for prostate cancer?
Although an elevated PSA (> 4) has the best positive predictive value, combining it with DRE is probably the most effective screening process.
prostate ultrasound
digital rectal examination (DRE)
DRE and prostate specific antigen (PSA)
PSA
Oncology