Specific test for gout is:
B i.e. Raised uric acid in synol fluid of joint - Gout is a metabolic disorder of purine catabolismQ, and characterized by high level of uric acid in the blood . Uric acid is end product of purine catabolismQ - Pyrimidine nucleotide unlike purine rings can be opened & degraded to highly water soluble structure like, p- alanine, /3? amino isobutyrate, NH3 & CO2. Excess meabolism of pyrimidine therefore does not give rise to clinical manifestationQ Human catabolizes purine (Adenine & Guamine) to uric acid, which is relatively insoluble acid.
Raised serum uric acid level
Raised uric acid in synol fluid of joint
Raised urea level
Raised urease enzyme level