All of the following are known to cause Lupus like syndrome, except
Answer is B (Penicillin): Penicillin is not associated with drug induced Lupus. Drugs repoed to induce Lupus-Like disease and associated autoantibodies: Agent Risk Agent Risk Antiarrhythmics Anticonvulsants Procainamide (Pronestyl) High Carbamazepine (Tegretol) Low Quinidine (Quinaglute) Moderate Phenytoin (Dilantin) Very low Disopyramide (Norpace) Very low Trimethadone (Tridone) Very low Propafenone (Rythmol) Very low Primidone (Mysoline) Very low Amiodarone (Cordarone) Very low Ethosuxamide (Zarontin) Very low Anti hypeensives Antithyroidals Hydralazine (Apresoline) High Propylthiouracil (Propylthyracil) Low Methyldopa (Aldomet) Low Anti-inflammatories Captopril (Capoten) Low D-Penicillamine (Cuprimine) Low Acebutolol (Sectral) Low Sulfasalazine (Arunfidine) Low Enalapril (Vasotec) Very low Phenylbutazone (Butazolidin) Very low Clonidine (Catapres) Very low TNF-a inhibitors (Remicade) Very low Atenolol (Tenonnin) Very low Mesalamine (Asacol) Very low Labetalol (Normodyne) Very low Zafirlukast (Accolate) Very low Pindolol (Visken) Very low Diuretics Minoxidil (Loniten) Very low Chlohalidone (Hygroton) Very low Prazosin (Minipress) Very low Hydrochlorothiazide (DiuchlorH) Very low Lisinopril Very low Antihyperlipidemics Antipsychotics Lovastatin (Mevacor) Very low Chlorpromazine (Thorazine) Low Simvastatin (Zocar) Very low Phenelzine (Nardil) Very low Atorvastatin (Lipitor) Very low Chlorprothixene (Taractan) Very low Miscellaneous Lithium carbonate (Eskalith) Very low Aminoglutethimide (Cytadren) Very low Perphanazine (Trilafon) Very low Interferon --a (Wellferon) - b - g Very low Antibiotics Timolol eye drops (Timoptic) Very low Isoniazid (INH) Low Ticlopidine (Ticlid) Very low Minocycline (Minocin) Low Nitroturantoin (Macrodantin) Very low
INH
Penicillin
Penicillin
Sulphonamide