All of the following are Indications for CSF examination in adults with all stages of Syphilis Except
Indications for Cerebrospinal Fluid Examination in Adults with All Stages of SyphilisAll PatientsAdditional Indications in HIV-Infected Persons1. Signs or symptoms of nervous system involvement (e.g., meningitis, hearing loss, cranial nerve dysfunction, altered mental status, ophthalmic disease , ataxia, loss of vibration sense), or2. RPR or VDRL titer >=1:32, or3. Active teiary syphilis, or4. Suspected treatment failure11. CD4+ T cell count <=350/mL, or2. All HIV-infected persons (recommended by some expes)Reference: Harrison&;s Principles of Internal Medicine; 19th edition; Chapter 206; Syphilis
RPR titer >= 1:32
VDRL titer < 1:32
Active teiary syphilis
Suspected treatment failure
Bacteriology