Which of the following is true about alpha 1 antitrypsin?
Alpha 1 antitrypsin : anti elastase protein coded by gene PiMM gene. Any mutation in this gene lead to abnormal formation of alpha 1 antitrypsin protein which leads to Storage of this abnormal enzyme inside hepatocyte instead of it's secretion resulting in manifestation of micronodular cirrhosis of liver and Pan acinar emphysema in basal pa of lung.
Inhibits elastase
Inhibits trypsinogen activation in pancreas
Inhibits trypsin activating protease
Inhibits chymotrypsin
NEET 2019