Mechanism of aspirin action is
Aspirin inhibits the synthesis of thromboxane A2 by irreversible acetylation of the enzyme cyclooxygenase.Other salicylates and nonsteroidal anti-inflammatory drugs also inhibit cyclooxygenase but have a shoer duration of inhibitory action because they cannot acetylate cyclooxygenase; that is, their action is reversible.Katzung 13e pg: 595
Conves inactive plasminogen into active plasmin
Inhibits COX and thus thromboxane synthesis
Enhances the interaction between antitrombin III and both thrombin and the factors involved in the intrinsic clotting cascade
Inhibits the glycoprotein IIb/IIIa complex
Endocrinology