Which of the following represent the mechanism of action of tetracycline?
Tetracyclines are bacteriostatic antibiotics. It inhibits protein synthesis by binding to 30S ribosomal subunit, and prevents the attachment of aminoacyl tRNA to the mRNA - ribosome complex. As a result peptide chain fails to grow. Ref: Essentials of Medical Pharmacology, 5th Edition, Page 668-73
Inhibits peptidyl transferase
Causes misreading of mRNA
Causes termination of peptide chain elongation
Binds to A site and inhibits attachment of tRNA