Alkanization of urine is done for:
Elimination of some drugs is by altering the pH Eg; alkalinization for weak acidic drugs, e.g. Barbiturates acidification of weak alkaline drugs or weak bases weak acids or weak bases- unionized forms- difficult to get eliminated strong acids and strong bases- ionized forms- could be eliminated easily Ref: KD Tripathi pharmacology 7th edition (page.no: 81)
Weak acid drugs
Weak basics drugs
Strong acidic drugs
Strong basic drugs
General pharmacology