Which is most commonly mutated gene in Surfactant Dysfunction Disorders:
ATP-binding cassette protein member 3 (ABCA3) is the most frequently mutated gene in sufactant dysfunction disorders. It is an autosomal recessive disorder and usually presents in the first few months of life with rapidly progressive respiratory failure followed by death.
Surfactant protein B
Surfactant protein C
GM-CSF
ATP-binding cassette protein member 3 (ABCA3)
Respiratory Distress Syndrome