Botulism causes
Clostridium botulinum produces Type A toxin. It acts by blocking the production or release of acetylcholine at the synapses and neuromuscular junction. Thus block neuromuscular transmission. Onset is marked by diplopia, dysphagia, and dysahria due to cranial nerve involvement. Symmetric descending flaccid paralysis is a characteristic pattern, ending in death by respiratory paralysis. Reference: Textbook of Microbiology; Anathanarayan and paniker's; 10th edition; Page no: 269
Descending flaccid paralysis
Descending spastic paralysis
Ascending paralysis
Ascending spastic paralysis
Bacteriology