Theophylline Overdose causes:
Theophylline has a narrow margin of safety. Adverse effects are primarily to the g.i.t., CNS and CVS. Children are able to develop CNS toxicity. Adverse effects include Dyspepsia, headache, nervousness, insomnia Restlessness, tremors, vomiting, palpitation, diuresis Agitation, tachypnoea, flushing, hypotension Death Convulsions, shock, arrhythmias Delirium, Increased muscle lone, extrasystoles, flashes of light seen. ESSENTIALS OF MEDICAL PHARMACOLOGY 6TH EDITION KD TRIPATHI Page No :221
Bradycardia
Seizures
Drowsiness
Bronchospasm
Respiratory system