Toxicity of ethanol is due to:
Ans. A. Increased NADH/NAD+ ratioHigh concentration of NADH leads to high NADH/NAD+ ratio. This is the basic cause of all metabolic alteration in alcoholism.
Increased NADH/NAD+ ratio
Decreased lactate/pyruvate ratio
Inhibition of gluconeogenesis
Stimulation of fatty acid oxidation
Nutrition & Digestion