Tophi in gout found in all regions except -a)  Joint capsuleb)  Skinc)  Muscled)  Articular cartilagee)  Synovial membrane
Tophi are pathognomic of gout. They are formed by large aggregations of urate crystals. The urate crystals are surrounded by -


Macrophages
Lymphocytes
Large foreign body giant cells


They are seen in the-


Articular cartilages of joints
Periarticular ligaments
Tendons and soft tissues
Achilles tendon
Ear lobes


Less common sites of involvement are -

a) Kidney
b) Nasal cartilage
c)  Skin of the finger tips, palms or soles.
ae
b
ab
ad