Tamsulosin, a adrenoceptor antagonist has affinity for which of the following receptors?
Ans. A. AlaVarious types a blockers of and their advantages in BPHa. Prazosin over Phenoxybenzamineb. Prazosin (selective a1 blocker) have better tolerability (less tachycardia and hypotension) over nonselective blockers.c. Doxazosin and Terazosin over Prazosind. Terazosin and doxazosin are long-acting drugs that need once a day dosing. But they need dose titration to minimize first dose hypotensione. Tamsulosin over Doxazosinf. Tamsulosin has minimal hypotension due to a1A selective blockade. But it causes increased ejaculatory dysfunction.g. Alfuzosin over all othersh. Therefore, there was a need for a long-acting selective a1 blocker that did not require dose titration, had minimal side effects on BP and ejaculatory function. This was provided by Alfuzosin
a I A
a I D
None of the above
Both (A) and (B)
A.N.S.