Loading dose is given for which of the following drug
Chloroquine is a drug having maximum Volume of Distribution (Vd >1300 L). This means it is mostly distributed in the tissues whereas the main site of its pharmacological action is RBCs. Therefore, it is given as a loading dose to attain steady state plasma concentration quickly. Chloroquine is a synthetic 4-aminoquinoline that has been the mainstay of antimalarial therapy, is the drug of choice in the treatment of erythrocytic P. falciparum malaria, except in resistant strains.
Diazepam
Propranolol
Chloroquine
Aspirin
Anti-Malaria Drugs