In a chronic smoker a highly malignant aggressive and metastatic lung carcinoma is
Cigarette smoking is most strongly associated with squamous cell carcinoma and small cell carcinoma. Small cell carcinoma variant is more malignant and metasizes Ref Harrison 19th edition pg 1702
Small cell carcinoma
Squamous cell carcinoma
Large cell carcinoma
Adenocarcinoma
Respiratory system