The daily production of hydrogen ions from CO2 is primarily buffered by which of the following?
Aerobic metabolism produces 13,000 to 24,000 mmol CO2 per day. This yields close to that amount of H+ ions produced per day the reaction: CO2 + H2O - H2CO3 - H+ + HCO3-At the tissues, CO2 diffuses into the red blood cells, where the enzyme carbonic anhydrase accelerates the above reaction.The H+ produced is buffered mainly by a large amount of hemoglobin in the red blood cells.Bicarbonate is not an effective buffer of volatile acid (from CO2).
Extracellular bicarbonate
Red blood cell bicarbonate
Red blood cell hemoglobin
Plasma proteins
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