Epitope spreading refers to
Ref Robbins 9/e p217 It is a phenomenon in which an immune response against one self antigens causes tissues damage releasing other antigens .and resulting in the activation of lymphocytes by these newly encountered epitope
A type of mechanism of spread of malignant tumor
One type of mechanism of HIV dissemination
A mechanism for the persistence and evolution of autoimmune disease
One of the mechanism of apoptosis
General anatomy