Which one of the following statements regarding pre-post clinical trials is most appropriate -
They use the patient as his or her own control. Pre-post clinical trial does not have a true control group. Each patient has a pre test score followed by a post test. Reference: Handbook of drug abuse prevention by Slobada & Bukoski; pg no.534-35.
They can not be randomized
They are useful in studies involving moality
They use the patient as his or her own control
They are usually easier to interpret than the comparable parallel clinical trial
Epidemiology