Sickle cell disease is present with which mutation:
Ans. (d) Base pair substitutionRef: Harper's Biochemistry, 30th ed. pg. 416-17A partial missense mutation (type of base pair substitution) glutamic acid, the normal amino acid in position 6 of the b chain, has been replaced by valine.
Cross-linked defect
Base pair defect
Mismatch defect
Base pair substitution
Proteins and Amino Acids