Which of the following drug is a 5HT2c agonist approved for treatment of obesity and causes Serotonin Syndrome as an adverse effect?
Lorcaserin: 5HT2c agonist Causes weight loss S/E: Serotonin syndrome Sibutramine: Serotonin and nor-adrenaline reuptake inhibitor Discontinued due to increased risk of stroke Modafinil: used in treatment of Narcolepsy Rimonabant: Inverse agonist of cannabinoid receptor - 1 Causes weight loss Prevents craving of alcohol S/E: psychological problems (withdrawn)
Lorcaserin
Sibutramine
Modafinil
Rimonabant
Histamine, 5-HT and PGs