Which of the following is the mechanism of action of IOP reduction of carbonic anhydrase inhibitors?
CA inhibitor: MOA- Inhibition of carbonic anhydrase isozymes present in ciliary processes of the eye with the consequent reduction of bicarbonate and aqueous humor secretion. Acetazolamide- (oral), Dorzolamide & Brinzolamide(topical). Mechanism of action: Decrease Aqueous Humor production. Oral CA inhibitors are Rapidly acting drug, can be used to terminate acute attack. S/E: Kidney stone, hypokalemia, acidosis, adrenal gland, renal failure . is an emergency drug & should not be answered as DOC for any type of glaucoma.
Increase uveoscleral outflow
Increase trabecular meshwork outflow
Decrease aqueous production
All of the above
Glaucoma