In inflammatory carcinoma breast with metastasis to axilla, treatment of choice:
Hallmark of inflammatory breast Ca is diffuse tumour involvement of dermal lymphatic channel breast & overlying skin, often without an underlying tumour mass. Presents with inflammatory changes like erythema, edema (peau de orange) warmth as a result of lymphatic obstruction. At least 33% skin over breast involved. History of rapid onset & progression. Inflammatory breast Ca is a clinical diagnosis & can occur with tumour of ductal or lobular histology Inflammatory breast Ca = stage T4d, corresponds to stage IIIB i.e. locally advanced breast Ca. Rx: NACT + MRM + .
NACT + MRM + Radiotherapy
Radical mastectomy plus chemotherapy
Radical mastectomy plus radiotherapy
Chemotherapy followed by hormone therapy
Breast