Ketosis is caused by -
Ans. is 'b' i.e., Over production of acetyl-CoA o Ketogenesis occurs when there is high rate of fatty acid oxidation in liver which provides excessine acetyl-CoA.o Normally, rates of ketone body synthesis and their utilization (oxidation) are balanced so that their serum concentration is maintained to very low level (normal is < 0.2 mmol/L or< 1 mg/d1) and urinary excretion is negligible (< 1 mg/ 24 hours).o However, when rate of ketogenesis exceeds their utilization, their concentration in blood rises, and the condition is known as ketonemia (hyperketonemia).o Excess ketone bodies are eliminated in urine, this is known as kenonuria.o The overall condition is called Ketosis.o Ketogenesis is usually associated with excessive fatty acid oxidation^ which occurs most notably in starvation and diabetes (type 1 DM).
Excessine utilization of glucose
Over production of acetyl-CoA
Excessine secretion of insulin
Excessine intake of carbohydrates
Oxidation of Fatty acids: Ketogenesis