Endothelium derived relaxing factor (EDRF) induced vasodilatation is mediated by:
Endothelial cells produce endothelium ­derived relaxing factor (EDRF), a substance that is now known to be nitric oxide (NO).
NO and ANP hormone act via increasing intracellular cGMP.
Increased intracellular cGMP
Decreased intracellular cGMP
Increased extracellular cyclic AMP
Decreased intracellular cyclic AMP