In Kidney which of the following is true?
Ans. is'd'i.e., Osmolarity of medullary interstitium is more than plasma(Ref: Guyton 12/e p. 334)The renal medulla shows an increasing osmotic pressure with increasing depth.Staing, with an osmolarity of 300 mOsm/L in the coex, the osmolarity reaches a level of 1200-1400 mosm/L at the pelvic tip of the medulla, i.e., The inner pa of medulla has highest osmotic gradient.That means that the renal medullary interstitium has accumulated solute in greater excess of water.
Osmolarity of tubular fluid in PCT gradually increases
Osmolarity of fluid in DCT is more than in Bowmann's capsule
Fluid coming out of descending limb of loop of Henle is hypotonic
Osmolarity of medullary interstitium is more than plasma