Force not acting in an enzyme substrate complex :
Vander Walls' forces are too weak, to actively paicipate in formation of enzyme- substrate complex. Forces contribute in binding are:- Hydrogen bondingQ- Ionic (electrostatic) bonding- Hydrophobic interactionEnzymes function to decrease the activation energy so that reactions can occur at normal body temperature. The substrate form a covalent bond with the enzymes active site, & accelerates the reaction.
Electrostatic
Covalent
Van der waals
Hydrogen