To rule out rheumatoid arthrirtis, most important among the followings is?
Ans. is 'b' i.e., HLA-DR4 o DR4 is strongly associated with RA(also with Type 1 DM Pemphigus vulgaris).Other optionso HLA-B27 is associated with seronegative spondyloartropathies (ankylosing spondylitis, Psoriatic arthritis, Reiter's syndrome, reactive arthritis) and acute anterior uveitis o HLA DR8 is associated with Type 1 DM.o HLA DQ1 is associated with pemphigus vulgaris.
HLA DR8
HLA DR4
HLA DQ1
HLA B27
Autoimmune Diseases