Features seen in hemolytic anemia are all except:
Answer is A (Tear drop cells are Burr cells) Tear drop cells and Burr cells are not characteristic of hemolytic anemias. Decreased levels of haptagobin, Reticulocytosis and haemoglobinuria are characteristic features of hemolytic anemia. Burr cells and Tear Drop cells- 'Pathology of Bone marrow and Blood cells (2004)' Burr Cells may be seen in cases of microangiopathic hemolytic anemia but the presence of burr cells alone is not characteristic of a hemolytic anemias. Burr cells (Echnocyte) Burr cells are an acquired RBC membrane abnormality with sho evenly spaced spicules. They may be seen in Renal failure (Uremia) - Characteristic feature Liver disease Burns Pyruvate kinase deficiency Gastric ulcers Cancer Microangiopathic Hemolytic Anemias Tear drop cells are drop shaped cells characteristic of marrow fibrosis. They are not a characteristic feature of hemolytic anemias. Tear Drop cells (Dacrocytes) Tear Drop cells are drop/ tear shaped RBC's characteristically seen in conditions associated with marrow fibrosis or extramedullary hemotopaesis They may be seen in Myelofibrosis Myelodysplastic syndrome Sideroblastic anemia Metastatic marrow infiltration These may also be seen in thalassemia, pernicious anemia and iron deficiency anemia Note Fragmented Erythrocytes seen in microangiopathic hemolytic anemia Helmet cellse Burr cells SchistocytesQ Taken from Heptinstall's pathology of the kidney 6th/703.
Tear drop and Burr cells
Haptoglobin
Reticulocytosis
Hemoglobinuria