Synol fluids of normal joints are usually devoid of collagen. Patients with rheumatoid diseases have various types of collagen in their synol fluid, depending on the tissue being damaged. If a patient has type II collagen in the synol joint, which of the following tissues is being eroded?
Type II collagen is present only in Hyaline and Elastic Cailages. Finding of type II collagen in the synol fluid of a joint indicates erosion of the aicular cailage. TYPE LOCATION Type I Dermis, tendon, ligaments and bone Type II Cailage, vitreous body, nucleus pulposus Type III Skin, vessel wall, reticular fibre of most tissues (lungs, liver, spleen...) Type IV Basement membrane
Vascular Endothelium
Compact Bone
Vascular Smooth Muscle
Aicular Cailage
Glands & Connective tissue