All of the following are true statements about Down syndrome, except:
ANTENATAL SCREENING FOR DOWN SYNDROME: TRIPLE TEST b-hCG || Maternal Serum Alpha fetoprotein (MSAFP) || Unconjugated Estriol (uE3) || QUADRUPLE TEST b-hCG || Maternal Serum Alpha fetoprotein (MSAFP) || Unconjugated Estriol (uE3) || Dimeric Inhibin-A || OTHER OPTIONS Down syndrome is most common inheritable cause of mental retardation- true Most common cause of Down syndrome is meiotic non-disjunction, followed by Robesonian translocation- true
Most common inheritable cause of mental retardation
In quadruple test, Inhibin-A level is reduced
Most common cause is meiotic non-disjunction
In triple test (AFP |, estriol |, hcG |)
Specific Cytogenetic Disorders