Ductus arteriosus closes in response to:
b. Indomethacin therapy(Ref: Nelson's 20/e p 2197, Ghai 8/e p 417)Indomethacin, a Prostaglandin inhibitor is used in medical closure of Ductus arteriosus.
Decrease in peripheral oxygen saturation
Indomethacin therapy
Prostaglandin E1
Increase in pulmonary vascular resistance
C.V.S.