An AIDS patient complains of headaches and disorientation. A clinical diagnosis of Toxoplasma encephalitis is made and Toxoplasma cysts were observed in a brain section. Which one of the following antibody results would be most likely in this patient?
(B) IgM nonreactive, IgG reactive (low titre) # One of the leading causes of death among AIDS patients is central nervous system Toxoplasmosis.> Toxoplasma infection is a result of reactivation of old or preexisting toxoplasmosis.> Occasionally; the infection may be acquired by needle sharing.> Because the disease is a reactivation of old or preexisting toxoplasmosis, routine quantitative tests for IgM antibody are usually negative and IgG titers are low (<1:256, IFA).> More sophisticated methods, such as IgM capture or IgG avidity, may reveal an acute response.
IgM nonreactive, IgG nonreactive
IgM nonreactive, IgG reactive (low titre)
IgM reactive (low titer), IgG reactive (high titer)
IgM reactive (high titer), IgG reactive (high titer)
Misc.