Primary role of antacids in peptic ulcer is?
Ulcer healing REF: Lippincott 5th edition page 478, Goodman Gillman page 638, Fundamental pharmacology for pharmacy technicians by jahangir moin page 262 However many authors believe that major role of antacid is pain relief I have a different opinion due to these direct quotation from Lippincott. "The rationale for the use of antacids in peptic ulcer disease lies in the assumption that buffering of H+ in the stomach permits healing. The use of both low and high doses of antacids is effective in healing peptic ulcers as compared with placebo" ALSO KNOW: Antacids are recommended only for the patient with mild, infrequent episodes of heaburn. Combinations of Mg2+ (rapidly reacting) and A13+ (slowly reacting) hydroxides provide a relatively balanced and sustained neutralizing capacity and are preferred by most expes. Simethicone, a surfactant that may decrease foaming and hence esophageal reflux, is included in many antacid preparations. For uncomplicated ulcers, antacids are given orally 1 and 3 hours after meals and at bedtime.
Pain relief
Ulcer healing
H Pylori eradication
All