In hereditary spherocytosis, an inherited abnormality is seen in which of the following red blood cell component?
Hereditary spherocytosis (HS) is caused by diverse mutations that lead to an insufficiency of membrane skeletal components. The pathogenic mutations most commonly affect ankyrin, band 3, spectrin, or band 4.2.
a-globin chain
b-globin chain
Phosphatidyl inositol glycan A
Spectrin
Hemoglobinopathies: Sickle cell anemia