True about Cinacalcet
The extracellular calcium-sensing receptor (CaR) on the parathyroid cell surface negatively regulates the secretion of PTH. Activation of the receptor decreases secretion of PTH, thereby decreasing bone turnover. Calcimimetics, such as cinacalcet, amplify the sensitivity of the CaR to extracellular calcium, altering the set point and thereby decreasing PTH production.Used in secondary hyperparathyroidismRef: Bailey and Love 27e pg: 831
Calcimimmetic
Calciuric
Decreases calcium absorption
Calcitonin
Endocrinology and breast