Choriocarcinoma is differentiated from invasive mole (chorio-adenoma destruens) by:
Choriocarcinoma is characterised by absence of villi
High titre of urinary chorionic gonadotrophin and cannon ball shadow in the X-ray lungs are found in both choriocarcinoma and invasive mole.
Presence of high titre of urinary chorionic gonadotrophin
Presence of cannon ball shadow in the lungs
Absence of villi structure on histological examination of the lesion
All of the above