Recent oral direct thrombin inhibitor which can be used for prevention of stroke is
Refer Katzung 11/e p 594 Ximelagatran was the first viral direct thrombin inhibitor approved, however it was later withdrawn because of hepatotoxicity. Recently a new direct thrombin inhibitor Dabigatrin had been approved for the prophylaxis of stroke and systemic embolism in nonvalvular atrial fibrillation
Dabigatrin
Ximelagatran
Lepirudin
Saxagliptin
Respiratory system