What does the term "bioavailability" mean?
Bioavailability is defined as the fraction of unchanged drug reaching the systemic circulation following administration by any routeBasic and clinical pharmacology Katzung 13th edition pg 47
Plasma protein binding degree of substance
Permeability through the brain-blood barrier
Fraction of an uncharged drug reaching the systemic circulation following any route administration
Amount of a substance in urine relative to the initial doze
General pharmacology