Renal artery stenosis is associated with -
Ans. is 'a' i.e., High renin Hypertension o The association of High aldosterone and High Renin levels in a hypertensive patient with hypokalemia suggests a diagnosis of Secondary' Hyperaldosteronism offrom Renal Artery Stenosis. Hypertension and hypokalemia |Plasma renin activity (PRA)Plasma aidoesterone concentration (PAC)|||| PRA| PACPAC-PRA ratio = 10| PRA| PACPAC-PRA ratio 5 20andPac >15 ng/dL (> 416 pmol/L)| PRA| PAC|||Investigate for causesof secondary hyperaldosteronismInvestigate forInvestigate for ||| Primary aldosteronismCongenital adrenal hyperplasia Exogenous mineralcorticoid DOC-producing tumor Cushing's syndrome 11 -beta-HSD deficiency Altered aldosterone metabolism Liddle's syndrome Glucocorticoid resistanceRenovascular hypertension Diuretic useRenin-secreting tumor Malignant hypertension Coarctation of the aorta DiseasesAldosteroneCortisolReninPrimary' Aldosteronism (Conn syndrome)HighNormalLowSecondary' Aldosteronism (e.g. Renal Artery Stenosis)HighNormalHighAdrenal insufficiency (Addison disease)LowLowHighCashing syndromeLow (may be normal)HighLow
High renin Hypertension
Normal renin hypertension
Low renin hypertension
Fibrinoid necrosis of vessels
Kidney