In cholecystectomy, fresh frozen plasma should be given -
The question is incomplete. It should be “A cirrhotic patient with abnormal coagulation needs cholecystectomy, FFP should be given:”
• Transfusions with FFP are given to replenish clotting factors.
• The effectiveness of the transfusion in maintaining hemostasis is dependent on the quantity of each factor delivered and its half-life.
• The half-life on the most stable clotting factor, factor VII, is 4 to 6 hours.
• A reasonable transfusion scheme would be to give FFP on call to the operating room.
• This way the transfusion is complete prior to the incision, with circulating factors to cover the operative and immediate postoperative period.
Just before operation
At the time of operation
6 hours before operation
12 hours after operation