Within the RBC, hypoxia stimulates glycolysis by which of the following regulatory mechanism?
Insulin sensitive (dependent) glucose transporter, GLUT- 4 that are found in adipose tissue and skeletal muscle are reduced in fasting state.
When the insulin levels are low,
Hypoxia stimulates pyruvate dehydrogenase by increased 2,3 DPG
Hypoxia inhibits hexokinase
Hypoxia stimulates release of all glycolytic enzymes from band 3 or RBC membranes
Activation of regulatory enzymes by high pH