A 45 year old diabetic patient has immunosuppressed with uncontrolled diabetes mellitus. The lesions are locally destructive and have eroded into the eye, palate, and central nervous system, often from an initial site in the sinuses. The organism can be difficult to culture. The appropriate treatment is:
Intravenous amphotericin but surgical debridement should also be strongly considered
Is intravenous amphotericin only
Surgical debridement only
Watchful observation
Intravenous amphotericin but surgical debridement should also be strongly considered