Osmotic damage is operative in all of the following complications of diabetes mellitus EXCEPT
Osmotic damage is inoperative in insulin- receptor deficiency. Insulin-receptor deficiency is the result of an increase in adipose, which down regulates receptor synthesis, and chronic elevation of glucose (glucose toxicity), which renders the receptors less receptive to insulin.
The formation of cataracts
Insulin receptor deficiency
Microaneurysms in retinal vessels
Peripheral neuropathy