A night shift worker complains of profuse Rhinorrhea and Sneezing for the past few days . Which among the following drug can be given to him ?
1st generation anti histamines 2nd generation anti histamines 1. Chlorphenaramine 2. Promethazine 3. Diphenhydramine 4. Cyclizine 5. Meclizine 6. phenaramine 1. Terfenadine 2. Fexofenadine 3. levocetrizine 4. Loratidine Note : All the 1st generation drugs can cross BBB and produce CNS actions so all 1st generation antihistamines can cause sedation. so 2nd generation antihistamines are given in this patients.
Promethazine
Fexofenadine
Chlorpheniramine
Pheniramine
Histamine, 5-HT and PGs