The following feature is common to both cytotoxic T - cells and NK cells -
Ans. is 'c' i.e., Effective against virus infected cells Natural killer cells o are first line of defense against virus laden cells and neoplastic cells o cytotoxity is not MHC restricted Cytotoxic T cells o they are antigen specific T cells whose function is to produce antigen specific lysis of target cells by direct cell-to-cell contact. o are usually CD, + class I MHC restricted T cells. o are impoant in defense against viral infections of tissues. Thus the feature common to both cytotoxic T-cells and NK cells is effectivity against virus infected cells. Cytotoxicity of different cells o Natural killar cells o Cytotoxic T-cells o Antibody dependent cytotoxic T-cells (ADCC) (a type of null cell) Not antibody dependent Not MHC restricted Class I MHC restricted Not antibody dependent Antibody dependent Not MHC restricted
Synthesize antibody
Require antibodies to be present for action
Effective against virus infected cells
Recognize antigen in association with HLA class II markers