What function do vitamin B12 and folic acid perform that is critical to hematopoiesis?
Cell proliferation requires DNA replication, which requires an adequate supply of thymidine triphosphate. Both vitamin B12 and folate are needed to make thymidine triphosphate.
Suppo porphyrin production
Serve as cofactors for iron uptake
Suppo terminal differentiation of erythroid and myeloid cells
Suppo production of thymidine triphosphate
Blood Physiology