True in alcoholic liver disease
Gynaecomastia is a marker of liver cell failure (not portal hypertension). 
 
The AST/ALT ratio is >2 in alcoholism as the ALT levels do not rise as much as AST due to pyridoxyl deficiency in alcohol abuse.  
 
HCV potentiates alcohol related liver damage. 
 
The CAGE questionnaire is used to diagnose alcohol related problems. 
 
Fagenstrom’s questionnaire is used to quantify addiction to nicotine in smokers.
Gynaecomastia is a marker of development of portal hypertension
ALT:AST ratio >2 is typical of alcoholic liver disease
Concomitant HCV infection accelerates development of Cirrhosis
Fagenstrom questionnaire is used to diagnose alcohol related problems in a patient