A patient is diagnosed with carcinoma of the breast. The most important prognostic factor in the treatment of this disease is
Recognition of the high risk associated with axillary metastases for early death and poor 5-year survival has led to the use of postsurgical adjuvant chemotherapy in these patients. Patients who have estrogen- or progesterone-receptive tumors (i.e., receptor present or receptor-positive) are particular candidates for this adjuvant therapy, as 60% of estrogen-positive tumors will respond to hormonal therapy. Age and size of the tumor are certainly factors of importance, but they are secondary to the presence or absence of axillary metastases.
Age at diagnosis
Size of tumor
Axillary metastases
Estrogen receptors on the tumor
Fetal Skull and Maternal Pelvis