Familial hypercholesterolemia is associated with
A positive correlation exists between the incidence of atherosclerosis and the plasma concentration of LDL cholesterol. The LDL (apoB-100, E) receptor is defective in familial hypercholesterolemia, a genetic condition which blood LDL cholesterol levels are increased, causing premature atherosclerosis.Ref: Harper&;s Biochemistry; 30th edition; Chapter 25; Lipid Transpo & Storage
Liver cirrhosis
Premature atherosclerosis
Nephrotic syndrome
Pancreatitis
Structure and function of protein