All are true of Dupuytren's contracture except -
Often both hands are affected (Bilateral disease), one more than the other.
The earliest sign is a small thickened nodule in the mid-palm opposite the base of ring finger.
Gradually this extends distally to involve the ring or little finger.
There is a rare, curious association with fibrosis of the corpus Cavernosum.
Usually 4th finger is involved
Bilateral disease is rare
Surgical release is useful
May be associated with Pyronie disease