Guthrie's bacterial inhibition test detects:
Guthrie's bacterial inhibition test:- Screening test for phenylketonuria (PKU) Used to detect the abnormal presence of phenylalanine metabolites in blood i.e. Phenyl pyruvate Phenyl alanine Phenyl lactate. Procedure: A small amount of blood sample is taken from heel of the infant and placed in a medium with a strain of Bacillus subtilis, a bacteria that cannot grow without phenylalanine. If phenylalanine metabolites are present, then these bacteria reproduce, and the test result is positive, indicating that patient has PKU.
Phenyl pyruvate
Phenyl alanine
Phenyl lactate
All of the above
Phenylalanine and Tyrosine metabolism Detail