True regarding cholangiocarcinoma
Based on macroscopic growth pattern cholangiocarcinoma divided into Sclerosing MC type Causes intense desmoplastic reaction Seen as diffuse thickening of the ducts without defined mass. This form is most diffucult to treat. Nodular Result in mass lesion Usually intrahepatic. Papillary Rare Low grade adenocarcinoma. Represented by polypoid mass filling the lumen of bile duct Minimal invasion and no desmoplastic reaction. More common in distal CBD. Associated with ourable outcome Ref: Sabiston 20th edition Pgno :1514-1518
Sclerosing variety is most common
Multifocal in 40%
Jaundice typically precedes pruritus
Adjuvant therapy improves survival
G.I.T