Following are the side effects of apradonidine except-
Apraclonidine (0.5%, 1%). It is also alpha-2 adrenergic agonist like brimonidine. It is an extremelypotent ocular hypotensive drug and is commonly usedprophylactically for prevention of IOP elevationfollowing laser trabeculoplasty, YAG laser iridotomyand posterior capsulotomy. It is of limited use forlong-term administration because of the high rate ofocular side-effects. Ref comprehensive ophthalamology AK Khurana 4th edition page no:425
Lid dermatitis
Follicular conjunctivitis
Eye lid retraction
Watering of mouth
Glaucoma