In an established case of coronary aery disease post MI which of the following drug will not prolong life expectancy?
After STEMI post-MI the LV undergoes changes in size, shape, and thickness called ventricular remodeling. This is reduced by ACE inhibitors, ARBs Statins administered at dose of Atorvastatin 80 mg provides long-term moality benefits Aspirin used daily reduces the incidences of clinical events and improve survival Other antiplatelet agents like clopidogrel, abciximab, tirofiban, and eptifibatide also improve survival No evidence that nitrates improve survival in myocardial infarction Trials Showing Improvement in Moality in Post Ml ACE inhibitors SMILE, GISSI and ISIS4 trial ARB VALIANT Spironolactone RALES
ACE inhibitors
Statin
Aspirin
Nitrate
Acute coronary syndrome