Blistering of skin is common in the presence of abnormal:
Intermediate Filaments are a pa of of cytoskeleton. They form a flexible scaffolding for cell which helps cell to resist external pressure. So in their absence cells rupture easily. Ref: Ganong's Review of Medical Physiology, 21st Edition, Page 13
Intermediate filaments
Centrosomes
Microfilaments
Microtubules