Best time to give Rh anti-D prophylaxis is:
Ans. (B) 28 weeks of pregnancy(Ref: Williams Obstetrics 24th/e p312)Anti-D immune globulin is given prophylactically to all Rh D-negative, unsensitized women at approximately 28 weeks, and a second dose is given after delivery if the infant is Rh D-positive Following delivery, anti-D immune globulin should be given within 72 hours.If immune globulin is inadvertently not administered following delivery, it should be given as soon as the omission is recognized, because there may be some protection up to 28 days postpartum.Anti-D immune globulin is also administered after pregnancy-related events that could result in fetomaternal hemorrhage.
12 weeks of pregnancy
28 weeks of pregnancy
36 weeks of pregnancy
After delivery
Immunomodulatory: DMARDS, Monoclonal Antibodies