Increased risk factor for carcinoma breast is
Risk factors of breast carcinoma Mutation of tumour suppressor genes BRCA1/BRCA2 is thought to be involved with high-risk of breast carcinoma Diet low with phytoestrogens and high alcohol intake have high-risk of breast cancer. Vitamin C reduces the risk. It is more common in nulliparous woman. Attaining early menarche and late menopause have high-risk of breast malignancy. Early child-bearing and breastfeeding reduces the chances of malignancy. Early 1st child bih reduces the risk; late first child bih after 35 years increases the risk. It is more common in obese individuals Ref; (page no;530 ) 5th edition of SRB&;S manual of Surgery.
BRCA1 mutation
Breast feeding
Multiparity
Smoking
Endocrinology and breast