Each of the following is a physiological uncoupler EXCEPT:
Ans. A. 2,4 dinitrophenol* Compounds that can uncouple or delink the ETC from oxidative phosphorylation, such compounds are known as uncouplers* As a result ATP synthesis doesn't occur.* 2,4 Dinitrophenol is an example of chemical uncoupler.Chemical uncouplers* Chemical uncouplers* Physiological uncouplers# 2, 4 dinitrophenol (has been extensively studied)# Thyroid hormones# Dinitrocresol# Long chain fatty acids# Pentachlorophenol# Unconjugated bilirubin# Tri fluoro carbonyl cyanide phenyl hydra zone (FCCP)* These act as uncouplers only at high concentration# Aspirin (high doses)
2,4 dinitrophenol
Thyroid hormone
Unconjugated bilirubin
Long chain fatty acid
Proteins and Amino Acids