The peripheral blood smear of a patient shows features of thalasemia, also presented with anaemia. Family history is also +ve. The investigation done to establish the diagnosis is :
Ans. is 'd' i.e. Hb- electrophoresisElectrophoretic techniques are used for routine hemoglobin analysis. It helps in quantification and identification of various hemoglobins.As we all are aware that thalassemia is a quantitative defect in Hb characterized by lack of certain types of hemoglobin and compensatory increase in other hemoglobin, therefore electrophoresis proves to be a reliable method for screening in thalassemia.
ESR estimation
Blood spherocyte estimation
Bone marrow aspiration
Hb-electrophoresis
Blood