Which causes raised angiotensin in blood?
A polypeptide in the blood that causes vasoconstriction, increased blood pressure, and the release of aldosterone from the adrenal coex. Angiotensin is formed by the action of renin on angiotensinogen, an alpha-2-glycoprotein that is produced in the liver and that constantly circulates in the blood. Renin, stimulated by juxtaglomerular cells in the kidney in response to decreased blood volume and serum sodium levels, acts as an enzyme in the conversion of angiotensinogen to angiotensin I, which is rapidly hydrolyzed to form the active compound, angiotensin II. The vasoconstrictive action of angiotensin II decreases the glomerular filtration rate, and the concomitant action of aldosterone promotes sodium retention, with the result that blood volume and sodium reabsorption increase. Ref: Ganong&;s Review of Medical Physiology, 23rd edition, page no: 670
Increased blood volume
Raised cardiac output
Decreased blood pressure
Increased sympathetic tone
Renal physiology