A 56 year old Chronic smoker, mass in bronchus resected. Most useful immunohistochemical marker to make a proper diagnosis would be ?
o Mass in bronchus in a old chronic smoker suggest bronchogenic carcinoma. The marker of carcinoma, on immunohistochemistry, is cytokeratin.o Other epithelial markers for carcinoma are :-Epithelial membrane antigen (EMA) :- Breast, lung and Kidney's adenocarcinoma.Carcino-embryonic antigen :- Carcinomas of GIT, pancreas, lung, breast, uterus and ovary.
Cytokeratin
Vimentin
Epithelial membrane cadherin
Leucocyte common antigen