In primary immune deficiency, the following plasma protein fraction is reduced -
Hypogammaglobulinemia is characterized by a decrease in the g component. It is seen in congenital immune deficiency syndromes or in association with diseases such as nephrotic syndrome, chronic lymphocytic leukemia, and coicosteroid treatment . Ref - Davidson 23rd edition pg 1063b
alpha-1 globulin
Alpha 2 globulin
Beta globulin
Gamma-globulin
Immune system