True about Alphal antitrypsin deficiency is?
ANSWER: (D) All of the aboveREF: Robbins 7th ed p. 913Alpha 1 antitrypsin deficiency:Due to protease inhibitor deficiencyIncreased neutrophill elastaseNeonatal cholestasis may occur,Hepatocellular carcinoma may also developPulmonary disease may occur in form of emphysemaGene located on chromosome 14
Deficiency of protease inhibitor
Autosomal recessive
May cause cholestatic jaundice
All of the above
Stomach and Intestines