A 28 year old woman underwent a feility sparing surgery for a 6x6 cm granulosa cell ovarian tumour. Which one of the following will you monitor for detection of recurrence?
GRANULOSA CELL TUMORS (NON EPITHELIAL-SEX CORD STROMAL TUMORS) Arise from granulosa cells Estrogen secreting functional tumors Presentation: abnormal uterine bleeding, precocious pubey Unilateral Call Exner bodies May cause endometrial hyperplasia and endometrial cancer (estrogen excess) Treatment: surgery: Unilateral salpingo-oophorectomy for feility sparing Tumor markers: INHIBIN A, INHIBIN B, CA 125, AMH Most commonly raised and most commonly used: INHIBIN B Most specific: AMH
Ca 19-9
LDH
Inhibin B
Placental Alkaline phosphatase (PLAP)
Ovarian Tumors