On increasing vagal tone following occurs in pacemaker
When the cholinergic vagal fibers to nodal tissue are stimulated, the membrane becomes hyperpolarizedThe slope of the prepotentials is decreased because the acetylcholine released at the nerve endings increases the K+ conductance of nodal tissue.Which cause rapid efflux of K+Ref: Ganong's Review of Medical Physiology Twenty-Third Edition Page No: 491
Increased K+ increased slop
Decreased K+ decreased slop
Increased K+ decreased slop
Decreased K+ increased slop
Cardiovascular system