In Down's syndrome, 2nd trimester quadruple test includes all EXCEPT:
Ans. (d) PAPP* The triple test measures the following three levels in the maternal serum: (sensitivity 71%)# Alpha-fetoprotein (AFP)# Human chorionic gonadotropin (hCG)# Unconjugated estriol (UE3)* Quadruple test include: triple test + Inhibin A: increases sensitivity upto 80%The levels may indicate increased risk for certain conditions: hCGAssociated conditionsLowLowHighDown's syndromeLowLowLowTrisomy 18 (Edward's syndrome)High--NTD, omphalocoele, gastrochisis
Alpha fetoprotein
HCG
Inhibin A
PAPP
Choriocarcinoma