Axicabtagene ciloleucel is used in:
CAR T-cell therapy:- A type of treatment in which a patients T cell are changed in laboratory so they will bind to cancer cells and kill them.Blood from a vein in Patient's arm flow through a tube to an apheresis machine, which removes the T cell and sends rest of blood back to the patient. CAR T cell are grown in the lab. The CAR T cell are able to bind to antigen on cancer cell and kill them. There are 2 FDA approved CAR T cell therapies:- Axicabtagene ciloleucel- Tisagenlecleucel Axicabtagene ciloleucel is use for diffuse large B cell lymphoma
Relapsed myeloma
T cell lymphoma
Diffuse large B cell lymphoma
Small cell lung Ca
JIPMER 2018