Which of the following is NOT a cause of congenital hypercoagulability aEUR'
Antiphospholipid antibody syndrome Congenital Factor V Leiden (5% of the population are heterozygous for FVL). Prothrombin mutation (G20210A, 5'UTR). High homocysteine levels due to MTHFR mutation Sickle-cell disease (only small risk) Antithrombin III deficiency. Protein C deficiency. Protein S deficiency. Plasminogen and fibrinolysis disorders (very rare) Acquired Antiphospholipid antibodies - Anti-cardiolipin antibodies and/or - Lupus anticoagulants Heparin-induced thrombocytopenia Paroxysmal nocturnal hemoglobinuria Nephrotic syndrome Hyperestrogenemia Estrogen-containing honnonal contraceptives Tobacco smoking Hyperhomocysteinemia due to vitamin B12 and folic acid deficiency
Protein C deficiency
Protein S deficiency
Antiphospholipid antibody syndrome
MTHFR gene mutations