Contraindication for the triptans is which of the following?
Ans. is 'd' i.e., All of the above Triptans* These are 5-HT1D/1B receptor agonists.* Sumatriptan is the 1st triptan to be developed. It is the drug of choice for aborting an acute attack of migraine.* Other triptans in clinical use are Almotriptan, eletriptan,frovatriptan, rizatriptan, eletriptan, naratriptan, and zolmitriptan.* All triptans can cause coronary vasospasm and are contraindiated in IHD. Other contraindications are hypertension, epilepsy, hepatic or renal impairment and during pregnancy.* The most important adverse effects are feeling of chest pressure, tightness and pain which may he accompanied by arrhythmia and MI and appear to be due to coronary vasospasm.
Ischemic heart disease
Epilepsy
Hepatic failure
All of the above
Miscellaneous (Pharmacology)