A diabetic female on INH and Rifamipicin for TB developed DVT. She was staed on warfarin, PT is not raised, and next step should be
Refer KDT Anticoagulant effect of warfarin is assessed by the measurement of prothrombin time Failure of elevation of PT indicates the decreased effect of warfarin Rifamipicin is the most effective drug for tuberculosis Acenococumarin is also an oral anticoagulant Effect of warfarin stas in 4-5days However heparin needs to be given by injection
Increase the dose of warfarin
Replace warfarin with Acenococumarin
Switch Ethambutol for Rifampicin
Use LMV heparin
Respiratory system