Which investigation should be done for diagnosis of idiopathic membranous glomerulopathy?
Membranous Glomerulopathy associate with Malignancy The anti-PLA2R antibody (Anti-phospholipase A2 Receptor antibody) attaches to the phospholipase A2 receptor (the antigen). The phospholipase A2 receptor is a protein found in the kidney filter (glomerulus), specifically within a cell called the podocyte which makes up pa of this filter Diagnosed by- protein in the urine and kidney biopsy
Antibody to PLA2R on podocytes
Kidney biopsy with immunofluorescent staining
C3, C4 and CH50 levels
c-ANCA titers
Nephrotic and Nephritic syndrome