Tricyclic antidepressants have all of the following actions except ?
Ans- B. MAO inhibitionTricyclic antidepressants (TCAS) are either NA + 5HT reuptake inhibitors (e.g. - Imipramine,Amitriptyline) or predominantly NA reuptake inhibitors (e.g. Desipramine, noriptyline).TCAs are not MAO inhibitors.Adverse effects of TCFs are : anticholinergic side effects, sedatior, mental confusion, weakness, increase appetite & weight gain, sweating & fine tremor, postural hypotension and cardiac arrhythmia.
Anticholinergic action
MAO inhibition
Block 5-HT or NE reuptake
Causes sedation