Which of the following infection is associated with the presence of Clue cells?
Clue cells are vaginal epithelial cells that are covered with bacteria giving them granular appearance and indistinct borders. It is a result of altered vaginal bacterial flora which occur in Bacterial vaginosis. Microscopic examination for clue cells is performed with a wet mount or a stained preparation using Papinicolaou or gram stain. Diagnosis of bacterial vaginosis requires the presence of 3 out of 4 clinical abnormalities: Objective signs of increased white homogeneous vaginal discharge. Vaginal discharge with pH of > 4.5. Positive Whiff's test or Amines test (addition of 10%KOH to vaginal discharge produces fishy odour, this is attributable to volatile amines such as trimethylamine). Microscopic demonstration of Clue cells.
Bacterial vaginosis
HSV 2 infection
Syphilis
Trichomoniasis