Longest acting drug among the following drugs for over reactive bladder:
Solefenacin is the longest acting drug from this group.
Gastro-intestinal tract

Anticholinergic drugs decrease the motility, tone and secretions in the gastrointestinal tract.

— Pirenzepine and telenzepine are selective M1 blockers useful in peptic ulcer disease.
— Hyoscine, dicyclomine, propantheline, oxyphenonium and clidinium are useful as anti-spasmodic agents for the treatment of intestinal colic.
— Darifenacin and solefenacin are selective M3 blockers useful for irritable bowel syndrome and overactive bladder.
Oxybutynin is shortest acting and solefenacin is longest acting drug from this group.
Mirabegron is a newer drug approved for overactive bladder. It acts by stimulating β3 receptors.
Oxybutynin
Trospium
Solifenacin
Flavoxate