All are true about ramelteon except
All are true for ramelteon except the statement that it has high addiction liability, in clinical trials on chronic insomnia patients, continuous nightly treatment with ramelteon maintained its effect to shoen sleep latency & was found to be free of rebound phenomenon on stoppage .No dependence producing potential has been noted so far. Ref KD Tripathi 8th ed.
Agonist at MT1 and MT2 receptors
Is a substrate of CYP1A2
Has high addiction liability
Approved for treatment of insomnia
Central Nervous system