Captopril can cause all Except:
Captopril is an ACE inhibitor- lowers BP. Reflex (postural) changes in plasma aldosterone are abolished and basal levels are decreased as a consequence of loss of its regulation by A-II. However, physiologically sufficient mineralocoicoid is still secreted under the influence of ACTH and plasma K+. Hyperkalaemia is more likely in patients with impaired renal function and in those taking K+ sparing diuretics, NSAIDs. *(REF.ESSENTIALS OF MEDICAL PHARMACOLOGY K.D TRIPATHI-6th EDITION.Page No-483,484)
Decrease in K+ concentration
Decrease in after load
Proteinuria
Blood dyscrasia
Cardiovascular system