Anion gap is increased by all except
Ans. d (Iron). (Ref. Harrison's Medicine 18th/ Chapter 47. Acidosis and Alkalosis; Table 47-4).Anion gap: (represent unmeasured anions in plasmaXCauses of increased anion gap metabolic acidosis# Ketoacidosis (DM, starvation, acidosis)# Lactic acidosis# Methanol, ethylene glycol, Salicylate toxicity# Renal failureAG = (Na+ + K+) - (Cl + HCO3); Normal AG = 10-12 mmol/L. (AI'2005)# The unmeasured anions include anionic proteins, phosphates, sulphates and organic anions.# An increased anion gap is often due to increase in unmeasured cations (Ca^, Mg+, K+)
Ethylene glycol
Methanol
Salicylates
Iron
Fluid & Electrolyte