Which of the following could inhibit the initiation of labor?
Antagonism of progesterone's effects, dilation of the cervix and oxytocin all increase uterine smooth muscle excitability and facilitate contractions and the onset of labor. LH would have no effect. Prostaglandin E2 strongly stimulates uterine smooth muscle contraction and is formed at an increasing rate by the placenta late in gestation.
Administration of an antagonist of the actions of progesterone
Administration of LH
Administration of an antagonist of PGE2 effects
Mechanically dilating and stimulating the cervix
Endocrine System