Poorest prognosis in AML is seen in which cyiogcnetic abnormality-
Monosomy 7 or paial deletion of the long arm of chromosome 7 (7q-) is a frequent cytogenetic finding in the bone marrow of patients with myelodysplasia (MDS) and acute myelogenous leukemia (AML) Ref Davidson 23rd edition pg 789
Monosomy 7
No cytogenetic abnormality
t(l5,i7)
inv, 16
Haematology