Increased permeability in acute inflammation is due to?
Ans. is 'a' i.e., Histamine Formation of endothelial gaps in venules, i.e. immediate transient response is the most common mechanism causing increased vascular permeability in acute inflammation. Mediators involved in this mechanism are :- Immediate (more impoant) : Histamine, bradykinin, leukotrienes, neuropeptide substance P. Somewhat delayed: IL-1, TNF, IFN-y
Histamine
IL-2
TGF-(3
FGF