E- cadherin mutation is seen in which type of carcinoma:
Loss of E cadherin can contribute to malignant phenotype by allowing easy disintegration of cell which can then invade locally and metastasize. Reduced cell surface expression of E cadherin has been noted in many carcinomas : Stomach carcinoma Breast carcinoma Prostate carcinoma Ovarian carcinoma
IDC
Lobular carcinoma
Metabplastic carcinoma
Metastasis
DNB 2018