Pathology in keratomalacia:
Breakdown of collagen fibres in corneal stroma occur in keratomalacia. VitA deficiency leads to keratomalacia in which cornea becomes dull and insensitive, hazy and yellow infiltrates form until finally the whole tissue undergoes necrosis and seems to melt away (keratomalacia) within a few hours. A characteristic feature is the absence of inflammatory reaction.
Accumulation of desquamated debris
Absence of mucus
Breakdown of collagen fibers in corneal stroma
Infection with corynebacterium xerosis
JIPMER 2017