Histological finding of solitary rectal ulcer syndrome is:
Mucosal prolapse syndrome/ solitary rectal ulcer syndrome d/t chronic mechanical stimulation Recognized in prolapsing colostomies, inflammatory polyps, solitary ulcer or prolapsing hemorrhoid at the site of rectum - Microscopically, there is Intercryptal erosion, hyperplasia of crypts (some have peculiar diamond shape). Obliteration of lamina propria by fibroblasts, elastin & smooth muscle cells from muscularis mucosae Reduction in number of lymphocytes & plasma cells Thickening of the muscularis mucosa with splaying of its fibers.
Thick collagen band under endothelial layer
Intraepithelial collection of lymphocytes
Crypt hypoplasia
Increased muscle layer proliferation
Intestinal Polyps, Colon & Anal Cancer