A 52-year-old woman with a history of systemic hypeension and chronic renal failure undergoes kidney transplantation, but the graft fails to produce urine. A renal biopsy is diagnosed as "hyperacute transplant rejection." Graft rejection in this patient is caused primarily by which of the following mediators of immunity and inflammation?
Hyperacute rejection Occurs within minutes to hours after transplantation. Manifested clinically as a sudden cessation of urine output, along with fever and pain in the area of the graft site. This immediate rejection is mediated by preformed antibodies and complement activation products. -Lymphocytes and macrophages (choices A, B, and C) are associated with acute and chronic graft rejection.
Cytotoxic T lymphocytes
Helper T lymphocytes
Mononuclear phagocytes
Preformed antibodies
Organ Transplant / Graft