Which one of the following statements about mechanism of action of Metformin is true?
Metformin decrease blood glucose by activating AMPK (Adenosine Mono Phosphate-activated protein Kinase) that helps in Decreasing production by - Inhibiting gluconeogenesis - inhibiting glycogenolysis Increasing utilization by -Stimulation of glycolysis -Uptake of glucose by muscles and fat.
Stimulate glycogenolysis
Stimulate hepatic gluconeogenesis
Enhance glucose uptake by skeletal muscle
Release insulin from beta cells of pancreas
Pancreas