“Smudge cells” in the peripheral smear are characteristic of:
In CLL, the peripheral blood contains increased numbers of small, round lymphocytes with scant cytoplasm. These cells are fragile and are frequently disrupted in the process of making smears, producing so-called smudge cells.
Chronic myelogenous leukemia
Chronic lymphocytic leukemia
Acute myelogenous leukemia
Acute lymphoblastic leukemia