Infeility in Kaagener syndrome is due to?
Asthenospermia or poor sperm motility is due to missing dynein arms, which is the basic defect of Kaagener's syndrome. It is a ciliopathic, autosomal recessive genetic disorder. Around 90% of individuals with kaagener's have ultrastructural defects affecting protein(s) in the outer and/or innerdynein arms. Triad consist of:- - situs inversus - chronic sinusitis - bronchiectasis.
Oligospermia
Blockage of epididymis
Asthenospermia
Undescended testis
Bronchiectasis