A 35-year-old male patient presented with a history of jaundice for 15 days. The onset was preceded by a prodromal illness. His serum tested positive for HBsAg. A clinical diagnosis of acute Hepatitis B was made. What should be the next best confirmatory investigation -
Antii-HBeAg antibody
HBe antigen
Anti-HBe IgM antibody
HBV DNA by PCR