Most common eye pathology in toxoplasma infection is: March 2009
Ans. B: Retinochoroiditis Intraocular features of toxoplasmosis infections are: Macular scarring Retinochoroiditis Vitritis When human retinal pigment epithelium (RPE) cells are infected with Toxoplasma gondii, there is an increased production of several cytokines including interleukin 1beta (IL-18), interleukin 6 (IL-6), granulocyte-macrophage colony-stimulating factor (GM-CSF), and intercellular adhesion molecule (ICAM). Patients with acquired toxoplasmic retinochoroiditis exhibit higher levels of IL-1 than asymptomatic patients. IL-10 polymorphisms associated with a low production of IL-10 also appear to be associated with the occurrence of toxoplasmic retinochoroiditis. Toxoplasma parasites are rarely identified in aqueous humor samples from patients with active ocular toxoplasmosis.
Corneal ulcer
Retinochoroiditis
Uveitis
Cataract