Which of the following syndrome is associated with mental retardation?
Disease name Abbretion Enzyme Defective GaG(s) affected Symptoms Hurler syndrome MPS I a-l-Iduronidase Dermatan sulfate, Heparan sulfate Mental retardation, coarse facial features, hepatosplenomegaly, cloudy cornea Hunter syndrome MPS II Iduronate sulfatase Dermatan sulfate, Heparan sulfate Mental retardation Reference: Harper; 30th edition; Page no:639; Table: 50-8
Hunter syndrome
Morquio syndrome B
Sly syndrome
Natowicz syndrome
Metabolism of carbohydrate