Which of these organs are not affected in autoimmune polyglandular syndrome type 2?
Ans. (c) Adrenal(Ref: Robbins 9th/pg 1130; 8th/pg 1155-1156, Harrison 18th/ chapter 318)Autoimmune polyglandular syndromeDiseaseGeneCharacteristicsAPS-1AIRE (Chr 21q)Autoimmune Poly Endocrinopathy, Candidiasis, and Ectodermal Dystrophy Q (APECED),Hypoparathyroidism, rarely lymphomasAPS-2HLA DR3,CTLA-4Hypothyroidism, hyperthyroidism, premature ovarian failure, vitiligo, type 1 diabetes mellitus, pernicious anemia
Parathyroid
Thyroid
Adrenal
Pancreas
Endocrine