All are true about cystic fibrosis except?
Ans. (c) Fasting hyperglycemia is a feature of early disease(Ref: Refer Ans 7 & 10; Nelson 19th/pg 1996; Robbins 9th/pg 466-470; 8th/pg 465-470)Cystic fibrosis-related diabetes (CFRD)No diabetes is seen in CF patients younger than 10 yr while 40-50% show diabetes at >=20yr age;So diabetes is a late feature of CF, seen only in individuals who survive to adolescence & beyond.Patients with CFRD have features of both T1DM and T2DM.There is pancreatic damage leading to slowly progressive insulin deficiency, along with insulin resistance
Recurrent respiratory infections
Majority of males are infertile
Fasting hyperglycemia is a feature of early disease
Sweat chloride is >70 meq/1
Disease of Infancy & Childhood