Which among the following is NOT a coenzyme of pyruvate dehydrogenase during the decarboxylation of pyruvate?
Pyruvate is oxidatively decarboxylated by pyruvate dehydrogenase (PDH) complex, producing acetyl CoA, which is the major fuel for the tricarboxylic acid cycle. This multienzyme complex requires five coenzymes: Thiamine pyrophosphate Lipoic acid FAD NAD+ Coenzyme A Pyruvate dehydrogenase is inhibited by its products, acetyl-CoA, and NADH Ref: Biochemistry By Richard A. Harvey (Ph. D.), Richard A. Harvey, Denise R. Ferrier, 2011, Page 114.
FAD
NAD
Folic acid
Lipoate