Which will the patient with following peripheral smear and X-ray spine present with?
Ref: Harsh Mohan, Textbook of Pathology, 7th ed. pg. 294-96The X-ray spine shows fish shaped vertebra with peripheral smear showing sickle shaped RBCs. The presence of sickling crisis lead to Hand-Foot syndrome is characterized by painful infarcts of the digits and dactylitis.
Hand Foot syndrome
Black urine
Elevated haptoglobin
Splenomegaly with gall stones
Blood