One of your staff nurse had a deep prick from the needle used to inject an HIV positive individual. What is the treatment regime that should be staed in her/him? Note that drug resistance was suspected in the HIV patient. \r\n
In this scenario ARVs should be initiated as soon as possible and no later than 72 hours. It should include 2 NI drugs. If drug resistance is suspected a protease inhibitor should also be added. The duration of treatment is 28 days. If the blood sample drawn from the exposed person is HIV negative at the time of exposure, the test should be repeated at 3 and 6 months. Ref: Park, Edition 21, Page - 328
2 NIs for 3 months
1 NI and 1 NtI for 28 days
2 NIs + 1 protease inhibitor for 28 days
2 protease inhibitor + 2 NtIs for 3 months