In the fasting state, which one of the following is utilized by the liver for gluconeogenesis?
Carbons from lactate, propionate (from odd-chain fatty acids and certain amino acids), glycerol (from fat stores), and amino acids (from muscle) can be used for gluconeogenesis. Fatty acids and ketone bodies are directly utilized for energy and are not used for gluconeogenesis. The end product of even-chain fatty acid oxidation is acetylCoA, which cannot be used as a precursor for net glucose production. Liver glycogen produces glucose through glycogenolysis.
Glycerol
Even-chain fatty acids
Liver glycogen
Ketone bodies
Nutrition & Digestion