Mechanism of hypokalemia in Gitelman syndrome is:
Hypokalemia is a feature of Gitelman's syndrome Mechanism: Mineralocoicoid excess Similar mechanism seen with Primary and secondary hyperaldosteronism Malignant hypeension Renin secreting tumors Renal aery stenosis Hypovolemia Bater's syndrome Apparent mineralocoicoid excess leads to hypokalemia in Liddle's syndrome 11 beta dehydrogenase-2 deficiency Ref: Harrison, Edition-18, page-352.
Mineralocoicoid excess
Apparent mineralocoicoid excess
Distal delivery of non reabsorbed anions
Magnesium deficiency