C-3 nephritic factor is associated with which of the following conditions?
Dense-Deposit Disease (type II MPGN) Resulting in excessive activation of the alternative complement pathway. Normally, this C3 convease is labile, but more than 70% of patients with dense-deposit disease have a circulating autoantibody termed C3 nephritic factor (C3NeF) that binds the alternative pathway C3 convease and protects it from inactivation.
MPGN Type 1
MPGN Type 2
Membranous nephropathy
Minimal change disease
Membranous Glomerulopathy and Membranoproliferative Glomerulopathy