The basis of combining Ritonavir with Lopinavir
Refer Katzung 10/e p810 Ritonavir is a microsomal enzyme inhibitor paicularly of CYP3A4 .it decreases the metabolism of other drugs and thus lower dose of Lopinavir can be used in treatment of HIV when combined with Ritonavir
Pharmaceutical compatability
CYP3A4 inhibiton NY Ritonavir
Long elimination half life of Ritonavir
Ability to counteract side effects of Lopinavir
General anatomy