Which of the following is characterstic sign of diabetic retinopathy?
The pathogenesis of Diabetic retinopathy is microangiopathy which occurs due to microvascular occlusion & leakage. There is degeneration and loss of pericytes in capillaries--> microvascular proliferation of endothelial cells -->thickening of basement membrane-->narrowed lumen of vessels.
Increase in pericytes
Thinned out capillary basement membrane
Lipohyaline deposits
Proliferation of endothelial cells
Retina