Positive feedback action of estrogen for inducing luteininzing hormone surge is associated with which of the following steroid hormone ratios in peripheral circulation:
A i.e. High estrogen, low progesteroneL H surge causes ovulationQ. For ovulation to occur the hormone picture should be high estrogen & low progesteronQEstrogenAt the time of ovulation, ova in the Graffian follicle needs to be well developed, which is accomplished by ' high estrogenQLH secretion is held in check by negative feedback effect of rising plasma estrogen.At 36-48 hours before ovulation estrogen feed back effect becomes positive & initiates a burst of LH secretion (LH surge)QProgesteronProgesteron is secreted by the corpus luteum, which is the remnant of graffian follicles after the ova has been released. Thus progesterone would rise only after ovulationQ.Large doses of progesterone inhibit LH secretion & potentiate the inhibitory effect of estrogen, preventing ovulation
High estrogen : low progesterone
Low esterogen : high progesterone
Low esterogen : low progesterone
High esterogen : high progesterone