Which of the following drug is implicated in the causation of osteomalacia of the bone?
Phenytoin inhibit the hepatic production of 25 hydroxy vitamin D and also directly inhibit bone mineralization and thus may result in osteomalacia. Steroids and heparin result in osteoporosis not osteomalacia. Impoant drugs causing osteomalacia are: Phenytoi Carbamazepine Valproate Phenobarbitone Bisphosphonates
Phenytoin
Steroids
Heparin
Estrogen
Osteoporosis, Sex Hormones and OCPs