Mechanism of action of vincristine in the treatment of all is
Ref-KDT 6/e 824,825 Vincristine is a chemotherapy drug that belongs to a group of drugs called vinca alkaloids. Vincristine works by stopping the cancer cells from separating into 2 new cells. So, it stops the growth of the cancer by polymerization
Inhibition of topoisomerse II to cause breaks in DNA standards
Alkylation and cross linking DNA standards
Inhibition of DNA mediated RNA synthesis
Inhibition of polymerization of tubulin to form microtubes
Other topics and Adverse effects