Drug kept as a last reso in the management of primary open angle glaucoma is -
Acetazolamide and methazolamide are not recommended for long term use because of their side effects. However, acetazolamide 250 mg Tds may be added to control IOP for sho term Ref :Ophthalmology A K Khurana 6th edition chapter-10 page no :237
Latanoprost
Topical beta blocker
Brimonidine
Oral acetazolamide
Glaucoma