All of the following statements about vinristine are true EXCEPT:
(Ref: KDT 6/e p824, 825) Vincristine is a vinca alkaloid. It acts in M-phase of cell cycle by inhibiting the formation of spindle. It is a marrow sparing drug and causes peripheral neuropathy as a prominent adverse effect. It is used for the treatment of hematological malignancies like Hodgkin's lymphoma and leukemias. It is ineffective against solid tumors.
It acts by inhibiting mitosis
Its prominent adverse effect is peripheral neuropathy
It does not suppress bone marrow
It is a drug of choice for solid tumors.
Other topics and Adverse effects