A drug is more likely to cause toxicity in elderly patients due to all of the following reasons EXCEPT:
Ans. is 'd' ie decreased volume of distribution Volume of distribution is increased with aging. This leads to decreased elimination of the drug and hence increased toxicity.Other changes seen with aging which lead to increased toxicity of drugsincreased sensitivity of the target organs*decreased renal excretion of drugs *decreased hepatic metabolism of drugs*body mass is decreased*
decreased renal excretion of drugs
decreased hepatic metabolism
increased receptor sensitivity
decreased volume of distribution
Pharmacodynamics