30 yrs old farmer treated initially with chloroquine for uncomplicated malaria now has an episode of relapse, what could be the reason for relapse?
Both Plasmodium ovale and Plasmodium vivax may have resting liver forms, which are very slow to develop into schizonts with merozoites and proceed onto the chloroquine-sensitive erythrocytic stages after treatment is over.
P. vivax has a significant level of chloroquine resistance.
P. vivax has a persistent exoerythrocytic stage (hypnozoite).
P. vivax has a persistent erythrocytic stage.
Chloroquine is not one of the drugs of choice.
Parasitology Pa 1 (Protozoology)