Transfusing blood after prolonged storage could lead to:
Prolonged storage of blood can lead to hyperkalemia due to lysis of RBC. Citrate intoxication, circulatory overload & haemorrhagic diathesis results from massive blood trasfusion. Citrate intoxication - Hypocalcemia, manifested by circumoral numbness and/or tingling sensation of the fingers and toes. Circulatory overload - Transfusion-associated circulatory overload (TACO). Dyspnea, bilateral infiltrates on CXR with systolic hypeension and elevated levels of Brain natriuretic peptide (BNP). Haemorrhagic diathesis - Dilutional thrombocytopenia
Citrate intoxication
Potassium toxicity
Circulatory overload
Haemorrhagic diathesis
Blood Bank & Transfusion Therapy