Which of the following drug can be used for closure of patent ductus aeriosus?
PGE2 and PGI2 keeps ductus aeriosus patent. If ductus aeriosus fails to close (patent ductus aeriosus) at bih, NSAIDs like aspirin and indomethacin are given to close it. In some congenital hea diseases (like transposition of great vessels), it becomes essential to keep ductus aeriosus patent before surgery. For this indication, alprostadil (PGE1) and epoprostenol (PGI2) can be given intravenously.
Paracetamol
Alprostadil
Indomethacin
Celecoxib
NSAIDs, Gout and Rheumatoid Ahritis