The most common prescription medication for sialorrhea
Traditional medications for the treatment of drooling target the reduction of saliva production using anticholin- ergic mechanisms. While they will reduce salivary output, they do not treat the underlying neuromuscular problems, so some patients may find the anticholinergic side effects out - weigh the benefit of the drug. Additionally, the drying effect these medications have can lead to xerostomia, especially if the patient has a constant open mouth. Glycopyrrolate is the most common prescription medication for sialorrhea and drooling , with atropine sulfate, scopolamine, amitriptyline, and benztropine also being reported in the literature. OnabotulinumtoxinA (Botox ) injections into salivary glands with ultrasonic guidance have shown to be of some benefit in patients who have failed or are intolerant to anticholinergics
Glycopyrrolate
Atropine sulphate
Scopolamine
Amitriptyline