Pyruvate Dehydrogenase complex has all enzyme components EXCEPT:
PDH complex has 3 enzyme components: 1. E1: Pyruvate Dehydrogenase 2. E2: Dihydrolipoyl Transacetylase 3. E3: Dihydrolipoyl Dehydrogenase REGULATION OF PDH End Product Inhibition Covalent Modification Acetyl CoA (in fasting) NADH Active in dephosphorylated state Done by Insulin
Pyruvate Dehydrogenase
Dihydrolipoyl Transacetylase
Dihydrolipoyl Dehydrogenase
Pyruvate Decarboxylase
Link reaction