All of the following are minor criteria for multiple Myeloma, Except
Answer is C (Plasmacytoma on tissue biopsy) Plasmacytoma or tissue biopsy is a major criterion for diagnosis of multiple myeloma (and not a minor criterion)
Plasmacytosis 20%
Multiple lytic lesions
Plasmacytoma on tissue biopsy
Monoclonal Ig spike < 2g/dl for IgA and < 3.5 for IgG