Ivabradine is used for management of ?
Ans. is 'a' i.e., Stable angina(Ref: KDT Vh/e p. 554; Cardiac drug development guide by Micheal Pugsley p. 381)IvabradineIt is an investigational inhibitor ofsino-atrial node.It is a relatively selective If(funny current) Sodium channel blocker of early pa of slow diastolic depolarization (phase 4) that reduces hea rate by inhibiting the hyperpolarization-activated sodium channel in SA node.Hea rate is a major determinant of angina in coronary disease.Therefore, lowering the hea rate is an impoant therapeutic approach in the treatment of stable angina.
Stable angina
Pre renal azotemia
Alzheimers disease
Anti smoking agent