The target antigen in dermolytic variant of epidermolysis bullosa is:
Epidermolysis bullosa is classified into 4 types depending on the level of cleavage: 1. Epidermolytic variant : Keratin 5 & 14 (most common antigen) 2. Lamina lucida lytic : Laminin 5 (most common antigen) 3. Dermolytic variant : Type 7 collagen (most common antigen) 4. Mixed variant : Kindlin-1 (most common antigen) Ref: Rook's Textbook of Dermatology, 8th Edition, Page 39.2.
Laminin 5
Keratin 5 and 14
Collagen 7
Kindlin-1