Which of the following drug does not cross the blood-placental barrier?
Ref:KD Tripathi pharmacology 7th edition (page.no: 19,116) Placental membranes are lipoidal and allow free passage of lipophilic drugs while restricting hydrophilic drugs. Glycopyrrolate is a quaternary ammonium compound. So it can't cross placenta and brain(BBB). Other drugs can cross the placenta
Atropine
Glycopyrolate
Physostigmine
Hyoscine hydro bromide
Autonomic nervous system