PPV23 is not recommended in?
Polysaccharide non-conjugate vaccine (PPV 23) contains capsular antigens of 23 serotypes. Dose: 0.5 ml , route: I/M preferred, can be given S/C also Children under 2 years of age & immunocompromised individuals do not respond well to the vaccine. Pneumococcal conjugate vaccine (PCV7)- for use in children 23 months and younger. PCV 23 recommended for selected groups like: Children above 2 yrs of age and adults. Post-splenectomy Sickle-cell disease pts. Chronic diseases of hea, lung, liver or kidney. Diabetes mellitus Alcoholics Generalized malignancies, organ transplants etc.
Pts with Sickle cell disease
Immunocompromised patients
Post-splenectomy
Pts with Diabetes mellitus
Contraindications, AEFIs