All have high hepatic clearance EXCEPT
(D) Paracetamol HEPATIC CLEARANCE OF DRUGSLOWHepatic ClearanceINTERMEDIATEHepatic ClearanceHIGHHepatic Clearance* Carbamazepine* Caffeine* Lignocaine* Diazepam* Fluoxetine* Morphine* Ibuprofen* Midazolam* Pethidine* Phenytoin* Omeprazole* Propranolol* Warfarin* Paracetamol* Zidovudine> Low Hepatic Clearance does not mean that the drug is then cleared by the kidneys; it indicates that the capacity of the hepatic enzymes involved in the metabolism of the drug is low.
Labetalol
Simvastatin
Morphine
Paracetamol
Miscellaneous (Pharmacology)