All of the following statements are true regarding ondansetron except:-
ONDANSETRON Main mechanism of action of ondansetron is 5HT3 antagonism. It has minor 5HT 4 agonist action which is clinically insignificant. It does not block dopaminergic receptors. It is drug of choice for chemotherapy induced vomiting, radiation induced vomiting and post-operative vomiting. No clinically significant drug interactions have been noted with ondansetron
It is antiemetic of choice for chemotherapy induced vomiting
It is a 5-HT3 receptor antagonist
It has significant drug interactions
It may possess 5-HT4 agonism
Histamine, 5-HT and PGs