All are true about sulphonyl ureas except?
Sulphonyl ureas are mainly used in Type 2 DM because Type 1 DM is characterized by autoimmune destruction of β - cells of pancreas and atleast 30% of β - cells should be present for sulphonyl ureas to be effective.
It blocks ATP sensitive K+ channels and increase insulin release
They have higher risk of causing hypoglycemia than meglitinides
They are used mainly in type 1 DM
Chlorpropamide can cause dilutional  hyponatremia