True about acetazolamide
Ref: Katzung's, 11th ed. pg. 416* Acetazolamide is a carbonic anhydrase inhibitor which acts on the proximal tubule of nephron.* In kidney, it inhibits H+ secretion and HCO3 reabsorption, which inturn reduces sodium reabsorption.* In eye, it reduces the aqueous formation by limiting generation of bicarbonate ion in ciliary epithelium.
Increase sodium reabsorption and potassium secretion
Carbonic anhydrase inhibitor
Acts at ascending limb of loop of Henle
Increase aqueous outflow mainly
G.I.T