Infection /multipilcation of HBsAg is best/commonly diagnosed by -
HBeAg appears in blood concurrently with HBsAg or soon afterwards. Circulating HBeAg is an indicator of active intrahepatic viral multiplication, and the presence in blood of DNA polymerase ,HBV DNA and virions ,reflecting high infectivity. REF:ANANTHANARAYAN AND PANIKER'S TEXTBOOK OF MICROBIOLOGY 9TH EDITION PAGE NO-547
HBeAg
HBsAg
HBV DNA
Anti HBs Ag
Virology