Oochronosis occurs in: (Repeat)
Ans: A (Alkaptonuria) Ref: Harrison's Principles of Internal Medicine, 18th ed.Explanation:AlkaptonuriaAutosomal RecessiveDue to deficiency of homogentisic acid oxidaseClinical featuresOochronosisArthritisCardiac valve involvementCoronary artery calcification Pigmented heart valves, sclera, joint, skin & renal calculiUrine darkens on standingNitisinone used to reduce urinary excretion of homogentisic acid
Alkaptonuria
Isovaleric aciduria
Phenyl ketonuria
Tyrosinemia
C.V.S.