A patient receives a toxic dose of lignocaine i.v., the patient is likely to exhibit:
(Ref: KDT 6/e p356) lf LA reaches the blood stream, most prominent adverse effects are related to CNS and CVS. ln CNS, stimulation (convulsions) followed by depression (coma) is seen. Initial stimulation is due to inhibition of the inhibitory neurons.
Excessive salivation
Mydriasis and diarrhea
Respiratory paralysis
Seizures and coma
Other topics and Adverse effects