Pathological changes of diabetic nephropathy are all except:
Diabetes may cause nodular and diffuse glomerulosclerosis but not focal glomerular sclerosis. Diabetes Mellitus - |ed glucose - non enzymatic glycosylation - Advanced glycation end products - efferent aeriole - |ed filtration injury - Nodular glomerulosclerosis ( most characteristic) : Kimmelstein Wilson lesion - diffused glomerulosclerosis ( |GFR )
Fibrin caps and capsular drops
Kimmelstein-Wilson lesion
Basement membrane thickening
Focal glomerular sclerosis
Systemic Disorders affecting Glomerulus