The conjugation of bilirubin to glucuronic acid in the liver;
Ans. is 'b' i.e. converts a hydrophobic compound to a hydrophilic one.Ref: Harrison 16th/e p 239 (15th/e p 255)Bilirubin is produced in the reticuloendothelial cells of spleen and liver. This unconjugated bilirubin is not soluble in water so is bound to albumin for its transfer in plasma.Liver uptakes this unconjugated bilirubin and conjugates it with glucuronic acid generating bilirubin glucuronide which is water soluble.For more on this topic see Question no. 12 Nov. 1999
Converts a hydrophilic compound to a hydrophobic one
Converts a hydrophobic compound to a hydrophilic one
Enables the bilirubin molecule to cross the cell membrane
Is increased during neonatal jaundice
Proteins and Amino Acids