Which of the following karyotype is seen in a nineteen year old female with sho stature, wide spread nipples and primary amenorrhoea?
Patient described in the question is most likely a case of Turner's syndrome as indicated by the clinical features. Turner's syndrome results from complete or paial loss of one X chromosome resulting in the karyotype 45X. It is primarily characterized by hypogonadism in phenotypic females. Ref: Robbins Pathologic Basis of Disease, 6th Edition, Page 174-5.
47, XX+18
46, XXY
47, XXY
45 X