Etanercept is a biological disease-modifying agent used in the management of rheumatoid arthritis. Its mechanism of action is:
Ans. (A) TNF alpha blockade(Ref: KDT 8th/e p943)TNF alpha blocking drugs are used in rheumatoid arthritis and Crohn disease. These include*Adalimumab*Certolizumab*Etanercept*Infliximab*Golimumab
TNF alpha blockade
COX-2 inhibition
IL-6 inhibition
Stabilization of mast cells
Immunomodulator