True statement about pulmonary embolism
Unfractionated Heparin UFH anticoagulates by binding to and accelerating the activity of antithrombin, thus preventing additional thrombus formation. UFH is dosed to achieve a target activated paial thromboplastin time (aPTT) of 60-80 s. The two principal indications for inseion of an IVC filter are (1) active bleeding that precludes anticoagulation and (2) recurrent venous thrombosis despite intensive anticoagulation. Ref Davidson edition23rd pg 620
Prompt heparin therapy will dissolve thrombi
Known risk factors include gastric cancer, AIDS
Most patients manifest dyspnea, pain, hemoptysis
Free floating iliofemoral thrombi are an indication for a caval filter
Respiratory system