ATP yield in Beta oxidation of palmitic acid ?
Energetics of Beta Oxidation (ATP Yield) - Palmitic acid (16 C) needs 7 cycles of beta oxidation. So, it gives rise to 8 molecules of acetyl CoA. Every molecule of acetyl CoA when oxidised in the TCA cycle gives 10 molecules of ATP. Each molecule of FADH2 produces 1.5 molecules of ATP and each NADH generates 2.5 molecules of ATP, when oxidised in the electron transpo chain. Hence, the energy yield from one molecule of palmitate may be calculated as: 8 acetyl CoA x 10 = 80 ATP 7 FADH2 x 1.5 = 10.5 ATP 7 NADH x 2.5 = 17.5 ATP Gross total = 108 ATP Net yield = 108-2 = 106 ATP. Ref: DM VASUDEVAN TEXTBOOK OF BIOCHEMISTRY, EIGHTH EDITION,PG.NO.,196.
106 ATP
102 ATP
120 ATP
110 ATP
Metabolism of carbohydrate