Failure of the choroid fissure to close results in
Failure of the choroid (optic) fissure to close results in a cleft of the iris--called coloboma iridis (mostly in inferonasal position). This defect may extend into the ciliary body, choroid, optic nerve, or retina. Congenital aphakia--absence of the lens--may result from defective development of the lens placode.
Congenital detached retina
Congenital aniridia
Congenital aphakia
Coloboma iridis
Eye, Nose and Ear