A 23-year-old female underwent kidney transplantation. After 8 days, she suffered from acute humoral rejection. She was successfully managed with tacrolimus and one more drug that suppressed B and T lymphocytes. Drug which target both B and T lymphocytes inhibiting de novo synthesis of purines is?
Mycophenolic acid is formed from mycophenolate mofetil. It inhibits inosine monophosphate dehydrogenase, the rate limiting enzyme in the de novo pathway of purine synthesis. This action suppresses both B and T-lymphocytes.
Cyclophosphamide
Mycophenolate mofetil
Methotrexate
Prednisone
Targeted Anticancer Drugs and Immunosuppressants