All of the following hormonal observations in PCOD are true, except -
Ans-C High levels of prolactin. PCOD 1. It is characterized by amenorrhoea or oligomenorrhea, obesity, hirsutism and often infertility. 2. The classical Stein Leventhal triad: a. anovulation, b. hyperandrogenism and c. obesity. 3. Both the ovaries are enlarged and covered with a thick, smooth fibrotic pearly white capsule. 4. Long term complications are: a. Hyperplasia of endometrium, b. Cardiovascular disease and c. NIDDM. 5. Lab: a. LH levels are raised, b. LH/FSH ratio is high (3:1), c. Estrogen may be high or normal, and d. Androgens are increased e. Progesterone is absent. 6. Rx: a. Clomiphene is drug of choice b. Estrogen break through bleeding occurs when estrogen stimulation of the endometrium is continuous and is not interrupted by cyclic progesterone withdrawal, as can occur in polycystic ovarian disease (PCOD c. Those who desire pregnancy can be induced to ovulate with clomiphene citrate or FSH and LH (Pergonal), and folliculogenesis can be monitored by USG. For hirsutism in polycystic ovary syndrome, GnRH analogues can be trieD.
High LH/FSH
High Androgens
High Prolactin
High LH