Which of the following is not a ourable prognostic marker in pediatric acute lymphoblastic leukemia (ALL)?
Favourable prognostic markers in pediatric ALL include age between 2 and 10 years a low white cell count hyperdiploidy trisomy of chromosomes 4, 7, and 10 the presence of a t(12;21) Several factors are associated with a worse prognosis: age younger than 2 years, largely because of the strong association of infantile ALL with translocations involving the MLL gene presentation in adolescence or adulthood peripheral blood blast counts greater than 100,000, which probably reflects a high tumor burden.
Hypodiploidy
2-10 years of age
Low WBC count
t(12;21)
Non Hodgkin Iymphoma