All of the following factor increase the risk of amino glycoside renal toxicity except -
Ans. is 'c' i.e., Simultaneous use with penicillin Nephrotoxicitv of aminoglycosides is potentiated by Advanced age, liver disease, diabetes mellitus, septic shock. Drugs - Amphotericin B, cyclosporine, vancomycin, ACE inhibitors, cisplatin. Longer course of therapy. Furosemide potentiates nephrotoxicity by causing volume depletion and hypokalemia.
Elderly person
Hypokalemia
Simultaneous use with penicillin
Aminoglycoside administration in recent past