Which of the following is true for tracheobronchial luminal neuroendocrine cells?
Ans. a. Contain serotonin (Ref: Ganong 24/e p638: Ganong 22/e p482-483)'Cells that manufacture amines in addition to polypeptide are sometimes called APUD cells (Amine Precursor Uptake and Decarboxylase) or neuroendocrine cells and are found in lungs and other organs in addition to the GIT. They are the cells that form carcinoid tumors.'- Ganong 22/e p482-483Biologically Active Substances Metabolized by the LungsSynthesized and used in lungs:* SurfactantSynthesized or stored and released into the blood:* Prostaglandins* Histamine* KallikreinPartially removed from the blood:* Prostaglandins* Bradykinin* Adenine nucleotides* Serotonin* Noeepinephrine* AcetylcholineActivated in the lungs:* Angiotensin I to angiotensin II
Contain serotonin
Contain catecholamines
Respond to decrease in pO2
Have only cholinergic nerve supply
Functional Anatomy - Respiratory System