Gene for Wilson's disease is ?
Ans is 'a' i.e. ATPB7 o Wilson's disease is an autosomal recessive disorder of copper metabolism caused by mutation of ATP7 B gene on the long arm of chromosome 13. ATP7 B gene encodes 'p-type' ATP responsible for copper excretion and incorporation into ceruloplasmin in the liver. The defect in ATP7 B gene results in copper accumulation in the liver (primarily) and other organs like eye and CNS.
ATP7B
B
C
D