Orphan annie eye nuclei appearance is characteristic of-
Orphan Annie eye nuclei is a feature of papillary carcinoma of thyroid. The nuclei of cells in papillary carcinoma thyroid has finely dispersed chromatin . Thus it is optically clear and shows ground glass or Orphan Annie eye nuclei. Ref: Robbins and cotrans 9e Pg 1095
Papillary carcinoma thyroid
Carcinoma pituitary
Paraganglioma
Meningioma
Endocrinology