Precursor of all steroid hormones ?
All steroid hormones originate from cholesterol.Steps involved in biosynthesis of various steroid hormones are as follows :?i) Cholesterol is first acted upon by desmolase to form a 21-carbon product pregnenolone, which is the biosynthetic precursor of all steroid hormones.ii) Pregnenolone is conveed to progesterone by dehydrogenase.iii) Progesterone is fuher conveed to glucocoicoids and mineralcoicoids by hydroxylations. These reactions are affected by monooxygenases which require cytochrome P-450 as an intermediate electrone carrier. These monooxygenases are -a) 17-hydroxylase and 21-hydroxylase Microsomalb) 11-hydroxyalse --> Mitochondrial
Pregnenolone
Deoxycoisol
Androstenedi one
Dehydroepiandrosterone