Which of the following statement are not related to pathogenesis of idiopathic pulmonary fibrosis?
Idiopathic pulmonary fibrosis aka Cryptogenic fibrosing alveolitis It is characterized by recurrent alveolar epithelial injury. SMOKING is one of the most impoant etiological factor. Seen in patient more than 50 years It is also associated with altered activity of surfactant. Histopathological Hallmark -Usual interstitial Pneumonia Rx-Lung transplant
Smoking
Age less than 20 years
Loss of function mutation in TE and TERC gene
Mutations in genes encoding components of surfactant
Interstitial lung diseases