Fluroquinolone mechanism of action in gram positive organism is by ?
Ans. is 'd' i.e., Topoisomerase IV Fluroquinolones Fluoroquinolones (including ciprofloxacin) inhibit DNA gyrase and topoisomerase IV. For gram negative bacteria, the primary target is DNA gyrase, while topoisomerase IV is inhibited in gram positive bacteria.
DNA gyrase
Topoisomerase II
Topoisomerase III
Topoisomerase IV