Gemfibrozil is:-
Gemfibrozil: MOA: Activation of the nuclear transcription receptor "peroxisome proliferator - activated receptor alpha" (PPAR-a). Major effects are to increase plasma HDL and to decrease plasma TG. Myopathy risk highest when used with statins Statins: Inhibit HMG COA reductase Inhibit cholesterol synthesis. EZETIMIBE- Inhibit intestinal cholesterol absorption.
HMG CoA inhibitor
PPAR-a activator
Inhibit cholesterol synthesis
Inhibit cholesterol absorption
Hypeension, Arrhythmias, Dyslipidemia