All are actions of coisol on the skin and connective tissue except
It is antiproliferative for fibroblasts and keratinocytes. Glucocoicoids in excess inhibit fibroblasts, lead to loss of collagen and connective tissue, and thus result in thinning of the skin, easy bruising, stria formation, and poor wound healing. Hyperpigmentation is a direct effect of ACTH on melanocoin 1 receptors.
Antiproliferative for fibroblasts
Antiproliferative for keratinocytes
Loss of collagen
Hyperpigmentation
Endocrinology