Best marker of SLE?
Ans. (b) Anti-ds DNA antibodies(Ref: Harrison 18th/chapter 319)Anti dsDNA is specific for SLE, only in high titers;But still, anti ds DNA is the best marker for SLE because its prevalence in SLE is 70%;Whereas, Anti Sm antibody, which is specific for SLE, but is seen in only 25% patients with SLE
Anti Sm antibodies
Anti-ds DNA antibodies
Anti-Histone antibodies
Anti Ro (SS-A) antibodies
Immunity