Hypospadias in the baby is caused by maternal use of which of the following drug?
Clomiphene is antiestrogens. It can cause hypospadias in the baby- in which the opening of the urethra is on the underside of the penis instead of at the tip Clomiphene, a drug used to induce ovulation, is chemically related to diethylstilbestrol (DES). DES is associated with vaginal adenocarcinoma among daughters and with hypospadias among second-generation male offspring. (REF. Essentials of medical pharmacology K D TRIPATHI 6 Edition, Page No 312)
Diethylstilbestrol
Tolbutamide
Clomiphene
Clobazam
Endocrinology