Cross-resistance can be one way or two way, one-way resistance can be seen in:
Organisms that develop resistance to an antimicrobial agent may also show resistance to other  chemically related AMAs. The cross-resistance among AMAs could either be one-way or two-way.  Cross-resistance among tetracyclines and sulphonamides is usually ‘two-way’.
Neomycin and streptomycin
Tetracycline and doxycycline
Sulphadiazine and sulphadoxine
None of the above