The action of non-competitive muscle blockers is affected by -
Ans. is 'a' i.e., Hypocalcemia Hypocalcemia has following effects It decreases vesicular ACh release at neuromuscular junction. It causes uncoupling of excitation and contraction. o By action 1. it will enhance the effect of both competitive as well as noncompetitive blockers due to unavailibility of ACh. o By action 2. it will enhance the effect of directly acting muscle relaxant (dantroline).
Hypocalcemia
Hyponatremia
Hypehermia
All of the above