Amsterdam criteria includes all except :
Revised Amsterdam Criteria : The revised Amsterdam criteria are used to select at-risk patients (all criteria must apply) Criteria: Three or more relatives who are diagnosed with an HNPCC-associated cancer (Colorectal, endometrium, small bowel, ureter or renal pelvis) in which one affected person is a first degree relative or the other two Atleast two successive generations are affected One or more cases of cancer are diagnosed before age 50 years FAP had been excluded, and tumors have undergone pathology review The Bethesda guidelines are established to direct patient selection for MSI testing Ref: Sabiston 20th edition Pgno : 1370
Atleast three relatives should be affected
All the three should be first degree relative
Two successive generations affected
FAP excluded
G.I.T