The drug used in Alzheimer's disease is
Tacrine was not discontinued due to hepatotoxicity Donepezil, gallatamine, rivastigmine can be used which are lipid soluble and can cross BBB easily Pyridostigmine and neostigmine are quaernary amines which do not cross BBB hence not used in Alzheimers Ref: KDT 6th ed pg 104
Tacrine
Rivastigmine
Pyridostigmine
Neostigmine
Autonomic nervous system