A woman develops chickenpox at a period of gestation of 8 weeks.What is the best method to exclude foetal varicella syndrome?
Ans. is b, i.e. Perform an ultrasound scan at 20 weeks.A detailed ultrasound examination carried out 5 weeks after infection, or at 16-20 weeks is the best method to exclude fetal varicella syndrome.Amniocentesis is not routinely advised because the risk of congenital varicella syndrome is low, even when amniotic fluid is positive for VZV DNA because amniocentesis has a strong negative productive value than a positive predictive valve.
Perform amniocentesis at 15 weeks and test for VZV DNA in the amniotic fluid
Perform an ultrasound scan at 20 weeks
Perform an ultrasound scan immediately
Perform chorionic villous sampling and test for VZV DNA
Medical & Surgical Illness Complication Pregnancy