Alpha-methyldopa is primarily used for
They act on central alpha 2a receptors to decrease efferent sympathetic activity. It decreases t.p.r more than H.R or C.O It is infrequently used now. (Ref: Essentials of medical pharmacology, K.D Tripathi, 7th edition, page 566)
Pregnancy induced hypeension
Renovascular hypeension
First line agent in hypeension
Refractory hypeension
Cardiovascular system