Denosumab is used in:-
Denosumab is a monoclonal antibody against RANK - ligand which inhibits binding to RANK receptor and inhibits the activation of osteoclasts and inhibits bone resorption so it is used in treatment of Osteoporosis.
Osteomalacia
Osteoahritis
Osteoporosis
Osteosarcoma
NSAIDs, Gout and Rheumatoid Ahritis