Mechanism of action of cholera toxin is through:
Cholera enterotoxin Light toxin: binds with ganglioside in epithelial cell membrane Heavy toxin: activates adenyl cyclase in epithelial cell wall which increase cAMP, leading to outpouring of isotonic fluid in lumen of intestine
Gangliosides
Adenyl cyclase
Gangliosides + adenyl cyclase
Exotoxin
Systemic Bacteriology (Haemophilus, Yersinia, Spirochaetes, Ricketssia, Chlamydia, Mycoplasma and Miscellaneous Bacteria)