Morphine when used for cancer palliative therapy least likely to cause:
Ans: c (Dry month)Ref: Tripathi 6th ed., Pg. 456Dry mouth has not been mentioned as an adverse effect of morphine. Other three choices are obvious.MorphineIt is a full agonist of mu receptors.Adverse effectsSedationLethargyVomitingConstipationRespiratory depressionAllergyWithdrawal features:1) Intense craving2) Restlessness and insomnia3) Pain in muscle and joints4) Running nose and eyes5) Abdominal cramps, vomiting, diarrhoeab) Piloerection, sweating, dilated pupils, tachycardia7) Disturbance of temperature control Antidote for morphine poisoning - naloxone
Nausea & vomiting
Constipation
Dry mouth
Respiratory depression
C.N.S