Which of the following disease modifying anti- rheumatoid drugs is a prodrug?
- Sulfasalazine is a pro-drug. - It dissociates in the colon to produce 5-ASA (MESELAMINE) and sulfapyridine. - 5-ASA is the active moiety in treatment of ulcerative colitis whereas sulfapyridine is used to treat rheumatoid ahritis.
Etanercept
Nimesulide
Sulfasalazine
Colchicine
NSAIDs, Gout and Rheumatoid Ahritis