A one-year-old boy presented with hepatosplenomegaly and delayed milestones. The liver biopsy and bone marrow biopsy revealed presence of histiocytes with PAS positive cytoplasm. Electron microscopic examination of these histiocytes is most likely to reveal the presence of:
Given scenario suggests Gaucher disease, in which glucocerebroside in lysosomes seen. Birbeck granules in the cytoplasm- seen in histiocytosis X
Birbeck granules in the cytoplasm
Myelin figures in the cytoplasm
Parallel rays of tubular structures in lysosomes
Electron dense deposit in the mitochondria
Lysosomal Storage Diseases