Most common cytogenetic abnormality in Multiple myeloma is
Multiple myeloma/solitary plasmacytoma: Genotype: Diverse rearrangements involving IgH; 13q deletionsSalient Features: older adults with lytic bone lesions, pathologic fractures, hypercalcemia, and renal failure; moderately aggressive Plasmacytoma: isolated plasma cell masses in bone or soft tissue; indolent Reference: Robbins and Cotran Pathologic Basis of Disease; 9th edition; Chapter 13; Disorders of white cells
Deletion 13q
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Haematology