All are true regarding folliculogenesis and ovulation except
Ovulation The LH surge initiates the continuation of meiosis in the oocyte, luteinization of the granulosa, and synthesis of progesterone and prostaglandins within the follicle Progesterone enhances the activity of proteolytic enzymes responsible, together with prostaglandins, for digestion and rupture of the follicular wall The progesterone influenced midcycle rise in FSH serves to free the oocyte from follicular attachments, to conve plasminogen to the proteolytic enzyme, plasmin, and to ensure that sufficient LH receptors are present to allow an adequate normal luteal phase The onset of the LH surge appears to be the most reliable indicator of impending ovulation, occurring 34-36 hours prior to follicle rupture A reasonable and accurate estimate places ovulation approximately 10-12 hours after the LH peak and 24-36 hours after peak estradiol levels are attained Reference: Clinical Endocrinologic Gynecology and Infeility, Eighth edition; Chapter 6
Follicular development and differentiation takes about 85 days
AMH suppos monofollicular development
First phase of follicular growth is gonadotropin insensitive
Elevated and static level of estradiol is essential for ovulation
Reproductive physiology and hormones in females