True statement is -
Ans. is 'd' Cyproterone acetate in a potent antiandrogen Reference see below.Clomiphene citrate is an antiestrogen It induces gonadotropin secretion in women by blocking estrogenic feed back inhibition of pituitary . It has no effect on hypothalamus Danazol - It has mild androgenic, anabolic and progestational activity. However the most prominent action is suppression of Gonadotropin secretion i.e. FSH and LH secretion Cyproterone acetate - It is a potent anti-androgen. It compete with dihydrotestosterone for the intracellular androgen receptor and inhibits its binding.Methimazole - Methimazole is an antithyroid drug which prevents the synthesis of thyroid hormones*
Clomiphene acts as antiestrogen both on pitatary and hypothalamus
Danazol increases FSH and LH both
Methimazole inhibits thyroxine release from thyroid
Cyproterone is a potent antiandrogen
Endocrinology