A 45 year old lady with normal PT and increased aPTT. About 2 year back, she was operated for cholecystectomy & did not have any bleeding episode.What is next investigation for clinical diagnosis ?
Answer- B. Dilute russel viper venom assayDilute Russel viper venom test is one of the test to detect lupus anticoagulant.Lupus anticoagulant is associated with prolongation in PTT and thrombosis (no bleeding)
Factor VIII assay
Dilute russel viper venom assay
Platelet aggregation test
Ristocetin cofactor assay