IVP of polycystic kidney disease shows:
Ans: D (Spider leg deformity) The calyces are enlarged & stretched over the cysts, which look like legs of a spider; hence called spider leg deformity"- Textbook of Surgery by 5 Das 5th/1155Autosomal Dominant Polycystic Kidney DiseaseMorphologyThe disease is universally B/L & the both kidneys are grossly enlarged , with multiple cyst studding the surface of the kidney.The cyst are spherical, vary in size from a few imltimeters to centimeters, & are distributed evenly throughout the cortex & medulla. Only 1 to 5% nephron will develop cysts.The cyst contain straw coloured fluid that may become haemorrhagic.Genetic ConsiderationOver 90% of cases are inherited as an AD-trait , with the remainder likely representing spontaneous mutations. Two form of ADPKD has been identified.ADPKD-1 accounts for 85% of cases & the gene has been mapped to chromosome 16p13.3. ADPKD-2 accounts for remainder cases & the gene has been mapped to chromosome 4q 21-23.ADPKD-2 appear to have a later age of onset of symptoms & renal failure than ADPKD-1.Radiological Feature Rim / Cresent Sign HydronephrosisSoap Bubble appearanceHydronephrosisSpider leg appearancePolycystic kidneyFlower vase appearance of ureterHorse shoe kidneyDrooping flower appearanceEctopic ureterCobra head appearanceUreterocoeThimble biadderTubercular cystic (chronic)Sandy patchesSchistosomiasis of bladderFish hook bladderBPH
Cobra head
Dropping lilly
Flower base appearance
Spider leg deformity'
Urography