Regarding efficacy and potency of a drug, all are true EXCEPT:
Ans. C. ED50 of the drug corresponds to the efficacyED5 corresponds to the potency of the drugED50 is the dose required to produce desired effect in 50% of individuals. Dose is related to potency not efficacyLD50 is the dose required to produce death in 50% of individualsTherapeutic index (TI): =ED50 LD50 It is a measure of safety of a drug.
In a clinical setup, efficacy is more important than potency
In the log dose response curve, the height of the curve corresponds with efficacy
ED50 of the drug corresponds to the efficacy
Drugs that produce a similar pharmacological effect can have different levels of efficacy
General Pharmacology