Which one of the following is NOT true about chemical mediators:
Leukotrienes are formed by Lipo-oxygenase , Whereas, prostaglandins are formed by cyclo-oxygenase. PGs causes vasodilation.
Leukotrienes are formed by lipo-oxygenase pathway
Histamine is a preformed chemical mediator
Prostaglandin causes vasoconstriction at the site of inflammation
Thromboxane A2 is associated with platelet aggregation
Inflammation