A 35 yr old female, mother of 3 children is observed to have CIN grade III on colposcopic biopsy. Best treatment will be:
Loop electrosurgical excision procedure (LEEP), also known as large loop excision of the transformation zone (LLETZ), uses electric current to generate waveforms through a metal electrode that either cuts or coagulates cervical tissues. LEEP is frequently used for treating CIN II and CIN III because of its ease of use, low cost, and provision of additional tissue for histologic evaluation. LEEP uses a small, fine, wire loop attached to an electrosurgical generator to excise the tissue of interest. Ref: Holschneider C.H. (2013). Chapter 48. Premalignant & Malignant Disorders of the Uterine Cervix. In A.H. DeCherney, L. Nathan, N. Laufer, A.S. Roman (Eds), CURRENT Diagnosis & Treatment: Obstetrics & Gynecology, 11e.
Cryosurgery
Conization
LEEP
Hysterectomy