Dobutamine causes -
Ans. is 'a' i.e., Increased cardiac output o Only prominent action of dobutamine is in increase in force of cardiac contraction and cardiac output without significant change in hea rate, peripheral resistance and BP. o In comparison to dopamine, dobutamine :? i) Does not cause renal or mesentric vasodilation. ii) Does not cause coronary vasoconstriction (no effect on alpha receptors). iii) Does not cause release of endogenous norepinephrine and does not precipitate arrythmia. If has an effect on peripheral resistance , always decreases it (Dopamine can increase or decrease peripheral resistance depending on the dose).
Increased cardiac output
Marked increase in hea rate
Increased total peripheral resistance
Marked increase in BP