Arrange the following drugs according to their half life in increasing order1. Amiodarone2. Adenosine3. Esmolol4. Omeprazole
Ans. AExplanation:* Amiodarone is longest acting anti-arrhythmic drug. Its half life is more than 3 weeks.* Adenosine is shortest acting anti-arrhythmic drug having half life less than 10 seconds.* Esmolol is an ultra short acting beta blocker. It is metabolized by pseudocholinesterase and thus has half life less than 5 minutes.* Omeprazole has half life of 1 -2 hours but works for 24 hours due to irreversible inhibition of proton pump.* Thus, the sequence isAdenosine < Esmolol < Omeprazole < Amiodarone
2, 3, 4, 1
2, 3, 1, 4
3, 2, 4, 1
2, 4, 2, 1
Miscellaneous (Pharmacology)