Area of brain resistant to neurofibrillary tangles in Alzheimer's disease:
Histopathological studies have shown that neurofibrillary tangles are rarely present in lateral geniculate bodies Neurofibrillary tangles : These are intracellular deposits made up of Tau proteins Amount & distribution of NFTs correlates with severity , distribution of Alzheimer NFTs are found commonly in following areas: Coical neurons (esp entorhinal coex) Hippocampus Amygdala Basal forebrain Raphe nuclei
Visual association area
Entorhinal coex
Lateral geniculate body
Cuneal gyrus area VI/temporal lobe
Organic Mental Disorders