In depression, there is deficiency of
The Karolinska Institute in Sweden first noted that low concentrations of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA) in the lumbar cerebrospinal fluid (CSF) were associated with suicidal behavior. CSF, neurochemical, and receptor studies suppo the hypothesis that reduced central serotonin is associated with suicide. Reference: Synopsis of Psychiatry, pages 766,767.
5-HT
Acetylcholine
Dopamine
GABA
Mood disorders