Which is the most active single chemotherapeutic agent in the treatment of leiomyosarcoma?
Ans. (A) Adriamycin(Ref: KDT 8th/e p926)Doxorubicin (adriamycin) and daunorubicin are anthracycline derivatives.Daunorubicin is mainly used for hematological malignancies (acute leukemia) whereas doxorubicin is used for solid tumors and soft tissue sarcomas.
Adriamycin
Daunorubicin
Methotrexate
Cisplatin
Chemotherapy: General Principles