True about Type I diabetes melitus is ?
Type 1 DM results from T cell mediated auto-immune destruction of the insulin secreting beta cells in the pancreatic islets and insulin deficiency. This autoimmune process is thought to be triggered by an infectious or environmental stimulus in genetically susceptible individuals. It can develop at any age, develops most commonly before 20 years of age. Thus it is insulin dependant and insulin improves the symptoms. Reference : page 803 Davidson's Principles and practice of Medicine 22nd edition and page 2403 Harrison's Principles of Internal Medicine 19th edition
Autoimmune disorder
Insulin non-dependent
Insulin does not improve the symptoms
Late age of onset
Endocrinology