Sildenafil acts by inhibiting?
Sidenafil, verdenafil, tadalafil acts by inhibiting PDE5 they increase NO- increases blood supply to the penis making it erect But they can produce ceain cardiac events They are also used in Pul HTN Ref: KD tripathi 8th ed
PDE 2
PDE 5
Adenyl cyclase
Gaunyl cyclase
Cardiovascular system