A 6-year-old boy is admitted to the ward with drowsiness, dull deep tendon reflexes and seizures. On examination the child has a line on gums and there is a history of constipation. Which will be most appropriate drug that should be used for this child?
A child with drowsiness, decreased deep tendon reflexes, seizures and grey line on gums suggests a diagnosis of Lead Poisoning, which can be treated with chelating agents like EDTA. Ref: Harrison's Principles of Internal Medicine - 16th Edition, Page 2404; Ghai Essential Pediatrics - 6th Edition, Page 133; KD Tripathy Pharmacology 5th Edition, Page 812-815; Nelson 17th Edition, Page 2360,2361.
EDTA
DMSA
BAL
Pencillamine