Alkalinization of urine is required to treat toxicity of all except:
Changes in urinary pH affect tubular reabsorption of drugs that are paially ionized - * Weak bases are ionize more and are less reabsorbed in acidic urine.* Weak acids ionize more and are less reabsorbed in alkaline urine. Urine is alkalinized in barbiturate, methotrexate and salicylate poisoning.
Salicylates
Barbiturates
Amphetamine
Methotrexate
Sympathetic System