What is the best time to give oral psoralen with UVA -
Ans is 'b' i.e. 1 hour before UVA Oral PUVAo In oral PUVA, 8-MOP is administered orally (0.6 -0.8 mg/kg body weight) 1 -3 hours before exposureo For 5-MOP the usual dose is 1.2-1.8 mg/kg body weight.Topical PUVAo A lotion containing 0.1-1 % 8-MOP is applied on the affected area and is exposed to UVA either immediately or after 1 - 2 hours.o Alternatively, a vanishing cream containing 0.01% TMP is applied 10-20 minutes before exposure.
Half hour before UVA
1 hour before UVA
Half n hour after UVA
1 hour after UVA