Calculate the loading dose of a drug whose systemic bioavailability will be 20%, Vd-200L and target concentration is 5gm/L
In pharmacokinetics, a loading dose is an initial higher dose of a drug that may be given at the beginning of a course of treatment before dropping down to a lower maintenance dose Loading dose-= 1000/20=5 Ref: KD tripathi 8th ed
1g
5g
12.5g
25g
General pharmacology