Which of the following is responsible for non-shivering thermogenesis in adults?
Brown adipose tissue is involved in metabolism, paicularly at times when heat generation is necessary. Thus, the tissue is extremely active in some species, in animals exposed to cold (nonshivering thermogenesis), and in heat production in the newborn. Though not a prominent tissue in humans, it is present in normal individuals, where it could be responsible for "diet-induced thermogenesis." It is reduced or absent in obese persons. The tissue is characterized by a well-developed blood supply and a high content of mitochondria and cytochromes, but low activity of ATP synthase. Metabolic emphasis is placed on oxidation of both glucose and fatty acids. Ref: Botham K.M., Mayes P.A. (2011). Chapter 25. Lipid Transpo & Storage. In D.A. Bender, K.M. Botham, P.A. Weil, P.J. Kennelly, R.K. Murray, V.W. Rodwell (Eds), Harper's Illustrated Biochemistry, 29e.
Thyroid hormone
Brown fat between the shoulders
Noradrenaline
Muscle metabolism