Which is not a 2nd generation anti-histamine agents
Anti histamines are classified into first generation and second generation compounds on the basis of CNS penetration and anti cholinergic propeies. First generation anti-histamine can penetrate blood brain barrier and possess additional anti cholinergic propeies which are lacking in second generation drugs. Cyclizine is a first generation where as cetrizine, loratidine and fexofenadine are second generation drugs Refer Goodman & Gilman 12/e p921
Cetirizine
Cyclizine
Loratidine
Fexofenadine
Autacoids