Cataract in diabetic patients is because of the accumulation of sorbitol in the lens. The enzyme responsible for this is –
NADPH+ dependent aldolase reductase reduces excessive glucose to sorbitol and intracellular accumulation of sorbitol causes osmotic changes resulting in cataract development.
Hexokinase
NADPH+ dependant aldolase reductase
Glucokinase
Phosphofructo isomerase