Which of the following is the most common gene delivery system for 'In-vivo' gene therapy?
Adenovirus in gene therapy: ds DNA virus Replication deficient Used in In Vivo approach gene therapy As vaccines, For cancer therapy Advantages: Remain as an episome (extrachromosomal DNA) So doesn't integrate into the genome. (no chance of inseional mutagenesis) The maximum size of the inse by the adenoviral vector is 36 kb.
Micro injection
Lipofection
Adeno viral vectors
Electroporation
Techniques in molecular biology