Which of the following is the most characteristic ultrastructural feature of paraganglioma on electron microscopy?
Electron microscopy examination of paragangliomas show membrane bound electron dense neurosecretory granules in the cytoplasm of tumor cells. Ref: Head and Neck Surgical Pathology By Ben Z. Pilch, Page 68; Dail and Hammar's Pulmonary Pathology: Neoplastic Lung Disease By Joseph F. Tomashefski, Page 533; Salivary Gland Diseases: Surgical and Medical Management By Robe Lee Witt.
Shrunken mitochondria
Large Golgi apparatus
Frequent mitoses
Dense core neuroendocrine granules