Lesions of which of the hypothalamic nuclei cause diabetes insipidus?
- Vasopressin, a 9-amino-acid peptide, has both anti-diuretic and vascular pressor activity - It is synthesized in the paraventricular & supraoptic nuclei of the hypothalamus. - Deficiency of Vasopressin causes Diabetes insipidus. - DI results in Polyuria & polydipsia Satiety center Ventromedial nuclei (VMN) Reward centre Medial forebrain bundle Circadian rhythm Suprachiasmatic nucleus Oxytocin Paraventricular nucleus
Dorsomedial nuclei
Supraoptic and paraventricular nuclei
Median preoptic nuclei
Ventromedial nuclei
Disorders of Pituitary Gland