Which of the following condition is associated with Osmotic diarrhoea?
Clinical causes of osmotic diarrhea that causes an osmolar gap greater than 50 includes lactase deficiency, sorbitol foods, saline cathaics and antacids. Osmotic diarrhea occur when water soluble molecules are poorly absorbed, remain in the intestinal lumen and retain water in the intestine. It usually follows ingestion of osmotically active substances. In this, Stool volume is less than 1 litre /day Diarrhea stops with fasting Stool has an osmolar gap (normal stool osmolar gap is less than 50) Ref: Mayo Clinic Internal Medicine Review, Eighth Edition edited by M. Habermann Thomas, page 262.
Lactase deficiency
Ulcerative sprue
Surreptitious ingestion of laxatives
Endocrine tumors