Prostaglandins are used in all except -
Ans. is 'd' i.e., Palliative treatment of PDA Prostaglandin and PDAo Prostaglandins mantain the patency of ductus arteriosus.o Therefore, prostaglandins are used to maintain the patency of ductus arteriosus for some CHD like transposition of great vessels.o For treatment of PDA to close this tract, NSAIDs like indomethacin are use as they inhibit the synthesis of prostaglandins and counteract their effect on ductus arteriosus. Important uses of PGs PGI2 (epoprostenal)PGE1 (Alprastadil)PGE2 (Dinoprostone)PGF2a (Carboprost)o For extracorporeal circulation in dialysis and cardiopulmonary bypasso To treat erectile dysfunctiono Intravaginally for induction of mid-trimester abortiono To control post partum hemorrhageo Intramniotic injection for inducing midtrimester abortiono To maintain the PDAo Primary pulmonary hypertensiono Misoprost - NSAIDS induced peptic ulcero For cerv ical ripening during labouro Lanatoprost increases the uveoscle- ral flow - used in glaucomao To maintain the patency of ductus arteriosus (PDA) o Misoprost - For induction of labour in first few weeks of pregnancy medical termination ofpregnancyo For storage of platelets for transfusion
Cervical ripening
PPH
Erectile dysfunction
Palliative treatment of PDA
Prostaglandins