The lymphocytic and histiocytic variant of Reed Sternberg cell is seen in
Lymphocyte Predominance Type: This uncommon "nonclassical" variant of HL accounts for about 5% of cases. Involved nodes are effaced by a nodular infiltrate of small lymphocytes admixed with variable numbers of macrophages. "Classical" Reed-Sternberg cells are usually difficult to find. Instead, this tumor contains so-called L&H (lymphocytic and histiocytic) variants, which have a multilobed nucleus resembling a popcorn kernel ("popcorn cell"). Eosinophils and plasma cells are usually scant or absent. L&H variants express B-cell markers typical of germinal-center B cells, such as CD20 and BCL6, and are usually negative for CD15 and CD30. Reference: Robbins and Cotran Pathologic Basis of Disease; 9th edition; Chapter 13; Diseases of White Blood Cells, Lymph Nodes, Spleen, and Thymus
Follicular center lymphoma
Lymphocyte depleted Hodgkins lymphoma
Nodular sclerosis Hodgkins lymphoma
Lymphocyte predominant Hodgkins diseases
Haematology