Increase in suicidal behaviour is due to
Karolinska Institute in Sweden first noted that low concentrations of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA) in the lumbar cerebrospinal fluid (CSF) were associated with suicidal behavior. This finding has been replicated many times and in different diagnostic groups.CSF, neurochemical, and receptor studies suppo the hypothesis that reduced central serotonin is associated with suicide. Reference: Synopsis of Psychiatry, page 766, 767.
Increase in serotonin
Decrease in serotonin
Increase in noradrenaline
Reactive depression
Mood disorders