Immunoglobulin isotype class switching is determined by -
Antibody genes also re-organize in a process called class switching that changes the one type of heavy chain Fc fragment to another, creating a different isotype of the antibody that retains the antigen specific variable region Ref: Ananthanarayan & Parkers textbook of microbiology 9th edition pg: 96
Constant region of light chain
Constant region of heavy chain
Variable region of light chain
Variable region of heavy chain
Immunology