Which among the following is a feature of denervation of smooth muscle?
ANSWER: (C) Increased sensitivity to chemical mediatorsREF: Ganong physiology 22nd edition page 111"When the motor Nerve supply to a smooth muscle is cut, the muscle does not atrophy (this is in contrast to skeletal muscle which atrophies on denervation), It becomes hyper responsive to the chemical mediators that normally activate it"
Atrophy of the muscle.
Decrease in no of receptors for neurotransmitters
Increased sensitivity to chemical mediators
Decreased neurotransmitter release At NMJ
Smooth Muscle: Contraction and Excitation