Patient has been given pencilling 48hrs ago, with no history of drug allergy. Now he develops wheeze hemolysis.antibody for pencilline is positive .type of hypersensitivity is which of the following
Ref Robbins 9/e p205 Administration of pencilline causing no symptoms in 48 hours with no previous history of allergy rules out type 1 hypersensitivity The patient presented with haemolysis which can be because of antibody formation against red cells the formation of autoantibody is a feature associated with type 2 hypersensitivity Thus clinically Transfusion reaction in which cells from an incompetent donar ract with and are opsonized by performed antibody in the host Hemolytic disease of the newborn : antigen difference between mother and foetus Autoimmune hemolytic anaemia ,agranulocytosis .and thrombocytopenia ,in which individual produce antibodies to their own blood cells ,which are then destroyed
Type 1
Type2
Type3
Type4
General anatomy