AML with worst prognosis:
PROGNOSIS OF AML: Good prognostic factors: t(8;21) inv16 t(15;17) CEBPA mutation NPM mutation Down syndrome Bad prognostic factors: Monosomy 7 5q deletion FLT3 - internal tandom duplication
8/21 translocation
Inversion 16
Normal cytogenetics
Monosomy 7
Neoplastic disorders of WBCs