Catecholamine hormones are synthesized in the:
Ans. A. Chromaffin cells of adrenal medullaCatecholamines are synthesized by tyrosine. DOPA forms Dopamine in the cytosol which by Dopamine oxidase (Cu containing) forms Nor-epinephrine in the Chromaffin granules of pheochromocyte. This reaction requires copper and Vitamin C. Nor-epinephrine then enters cytoplasm and undergoes methylation by methionine to form Epinephrine. Both after synthesis enters in the chromaffin granules for storage.
Chromaffin cells of adrenal medulla
Zona glomerulosa of adrenal cortex
Zona fasciculate of adrenal cortex
Zona reticularis of adrenal cortex
Endocrinology