Which is true about gallstones
Recently bacterial infection has been shown to play the role in pathogenesis of gallstone, this adds to the growing pool of studies finding an infectious nidus in these gallstones Brown stones are related to bile statsis and infection Gram negative bacteria (E.coli and Klebsiella) secretes beta-glucuronidase, which deconjugate soluble conjugated bilirubin Free unconjugated bilirubin precipitates and combines with calcium and bile to form brown pigment stones. Stones from whenever static foreign bodies are present in the bole duct (stents or parasites such as clonorchis sinensis and Ascaris lumbricoides Ref: Sabiston 20th edition Pgno : 1492
Pigment gallstones are most common
Bacterial nidus of infection may be seen
Even if asymptomatic gallbladder should be removed
They are mostly solitary
G.I.T