Therapeutic drug monitoring of plasma concentration of antihypeensive drugs is not practiced because
Ref-KDT 6/e p34 TDM is done for drugs (with narrow therapeutic index) whose response cannot be monitored by clinical examination. Antihypeensive effect can be easily measured, therefore TDM is not required
Determination of plasma level of these drugs is quite tedious and long process
It is easier to measure the effect of these drugs
Antihypeensive effect do not increases linearly with the dose
All Antihypeensive drugs are prodrugs
Other topics and Adverse effects