Thyroxine binding globulin (TBG) is increased in:
TBG concentration increases in (conditions of high estrogen levels) such as: pregnancy oral contraceptives. TBG concentration is decreased by: Hormones ( androgens, glucocoicoids;) Malnutrition nephrotic syndrome cancer chemotherapy. Drugs, such as phenytoin, salicylates.
Glucocoicoid therapy
Nephrotic syndrome
Pregnancy
Cancer chemotherapy
Endocrine System