Which of the following drugs when combined erythromycin may cause ventricular arrhythmias?
- Erythromycin causes inhibition of CYP3A4 enzyme. - As a result of this, level of Cisapride rises in blood - High blood levels of Cisapride causes QT prolongation and leads to Torsades-de-pointes (ventricular arrythmia) so, the combination is avoided.
Tetracycline
Streptomycin
Ebastine
Cisapride
Gastro-Intestinal Tract