The complementarity-determining regions are-
In the variable region of the H and L domains, maximum sequence variation is concentrated in a few discrete regions called hyperevariable regions ( HV) . HV regions form the antigen binding site of the antibody molecule which is complementary to the structure of the epitope and are called Complementary Determining Regions (CDRs)
Restricted to light chains
Are in the constant pa of the Ig molecule
Binds to Fc receptor
Are concerned in antigen recognition
Immunology Pa 1 (Immune Response, Antigen-Antibody Reactions, Hypersensitivity, Structure of Immune System, Immunodeficiency Disorders)