All are true statements regarding Lemborexant except :
Lemborexant FDA approved drug for the treatment of insomnia which got its approval after two Phase III clinical trials namely SUNRISE I and SUNRISE II. Useful in insomnia ,characterized by difficulties with sleep onset and/or sleep maintenance. Orexin neuropeptide signaling system plays a role in wakefulness. Blocking the binding of wake-promoting neuropeptides orexin A and orexin B to orexin receptors OX1R and OX2R is thought to suppress wake drive. Lemborexant binds to orexin receptors OX1R and OX2R and acts as a competitive antagonist with stronger inhibition effect to OX2R most common adverse effect is somnolence
It is used in the treatment of Insomnia
It is an orexin receptor agonist
It is useful in patients with difficulties with sleep onset/maintenance
The most common adverse effect is somnolence
Sedative-Hypnotics and Parkinsonism