A 50 yr. old male presented with chronic breathlessness and intermittent jaundice. He denies smoking and alcohol abuse. Lung and liver specimens revealed the following findings respectively What is the most probable diagnosis?
The lung specimen reveals diffusive panacinar emphysema. The liver biopsy shows PAS positive diastase resistant deposits. Both the above clues point towards option C. - Option A hemochromatosis would show pearls stain on liver biopsy. - Cystic fibrosis would show bronchiectasis.
Hemochromatosis
Cystic fibrosis
Alpha 1 antitrypsin deficiency
Wilsons disease
Integrated QBank