All are false about tigecycline, except:
Ans. d. Not preferred in UTIRef: Goodman Gilman 12th e/P 1523Tigecycline, doxycycline and minocycline are safe in renal failure.Tigecycline is active against gram negatives with the exception of pseudomonas, providencia, morganella and proteus.Tigecycline has poor bioavailability and hence is given only by parenteral route.Tigecycline is poorly concentrated in urine and hence should be avoided in treatment of urinary tract infection.
Dose reduction in renal failure
90% pseudomonas strains are sensitive
Oral and parenteral bioavailability is same
Not preferred in UTI
Anti Microbial