Trisomy of which chromosome is associated with uterine fibroids?
Fibroids are monoclonal and about 40% have chromosomal abnormalities that include translocations between chromosomes 12 and 14, deletions of chromosome 7, and trisomy of chromosome 12.Cellular, atypical, and large fibroids are most likely to show chromosomal abnormalities.Ref: Berek and Novak&;s Gynecology; 15th edition; Chapter 15
Trisomy 10
Trisomy 11
Trisomy 12
Trisomy 14
Uterine fibroid