HMG-Co-A Reductase is associated with
(B) Familial Hypercholesterolemia # HMG-CoA reductase (or 3-hydroxy-3-methyl-glutaryl-CoA reductase or HMGR) is the first enzyme of the HMG-CoA reductase pathway, the metabolic pathway that produces cholesterol and various other biomolecules.> HMG-CoA reductase is a polytopic, transmembrane protein that catalyzes a key step in the mevalonate pathway which is involved in the synthesis of sterols, isoprenoids and other lipids.> HMG-CoA reductase is the rate-limiting step in cholesterol synthesis and represents the sole major drug target for contemporary cholesterol-lowering drugs.
Type 2 Diabetes
Familial Hypercholesterolemia
Gaucher's disease
Abetalipoproteinemia
Miscellaneous (Bio-Chemistry)