At any given point during the pregnancy, AFP levels are highest in:
Alpha Fetoprotein in the fetal serum is the highest. It is 1000 times more than maternal serum. AFP levels are increased in omphalocele, gastroschisis, NTDs, Anencephaly. AFP are low in trisomy, trophoblastic diseases, maternal obesity, overestimated gestational age, intrauterine death
Fetal serum
Placenta
Amniotic fluid
Maternal serum
Physiological Changes of Pregnancy