Dr. Shweta decided to add a progestin for 10-12 days each month to estrogen replacement therapy in menopausal women in the gynaecology OPD. Addition of progestin is recommended because the progestin:
Use of estrogen for the treatment or prevention of post-menopausal osteoporosis --> increase risk of breast and endometrial carcinoma. Progesterone is used to decrease the risk of endometrial carcinoma.
Blocks the increased risk of myocardial infarction due to estrogen
Blocks the increased risk of endometrial carcinoma due to estrogen
Reverses vulval atrophy occurring in post menopausal women
Enhances the metabolic benefits of estrogen treatment
Osteoporosis, Sex Hormones and OCPs