Regarding the lipid or liposomal formulation of amphotericin B which of the following statements is accurate
Ref-KDT 6/e p758 Newer liposomal preparations of amphotericin B have the following features: Less chances of nephrotoxicity and infusion related reactions Lesser uptake in the tissues like kidney More expensive Similar in efficacy and antifungal spectrum as conventional preparations
They are expensive to use than conventional amphotericin B
There are more effective in fungal infections than conventional preparations because they increase tissue uptake of amphotericin B
They may decrease the niprotoxicity of amphotericin B
They have wider spectrum of antifungal activity than conventional formulation of amphotericin B
Other topics and Adverse effects