Oxaloacetate + Acetyl CoA → Citrate + CoASH. This reaction is
There are two irreversible steps : (i) Oxaloacetate to citrate, catalyzed by citrate synthase, and (ii) α - ketoglutarate to succinyl CoA, catalyzed by α - ketoglutarate dehydrogenase.
Reversible
Irreversible
Can be reversed by catalase
Competitive