All are true regarding agammaglobulinemia except -
In agammaglobulinemia all classes of immunoglobulins are grossly depleted in the serum. Tonsils & Adenoids are atrophic. Lymph node biopsy reveals depletion of cepls of bursa dependent areas. Plasma cells and germinal centres are absent even after antigenic stimulation. There is marked decrease in the poion of B cells in circulation. Ref: Ananthanarayan & Panikers textbook of microbiology 9th edition pg.no. : 171,172
Loss of germinal centre in lymph node
Normal coical lymphocytes
Normal coical lymphocytes in paracoex and medulla
Decreased red pulp in spleen
Immunology