True about adrenal pheochromocytoma is
Refernce Robbins page no 1134 The "10 percent rule" forpheochromocytoma/paraganglioma--10% familial, 10% malignant, 10% extra-adrenal--is therefore no longer tenable. Current roles of pathology are limited to diagnosing primary or metastatic tumors and identifying features suggestive of malignant potential or hereditary disease.
Chromaffin negative
Mostly malignant
Bilateral in 10 percnt cases
Unilateral in 10 percnt cases
Endocrinology