The histology of Lobular carcinoma of breast reveals-
Invasive lobular carcinoma consists of cells morphologically identical to the cells of LCIS. Two thirds of the cases are associated with adjacent LCIS. The cells invade individually into stroma and are often aligned in "single-file" strands or chains. This growth pattern correlates with the presence of mutations that abrogate the function of E-cadherin, a surface protein that contributes to the cohesion of normal breast epithelial cells. ref : Robbins Basic Pathology, 9E,page-711 REF of IMG :
Single file pattern
Pleomorphic cells in sheets
Clustersl/lslands of cells with mucous lakes
Solid syncytium like sheets
Breast