True about Alpha1 antitrypsin deficiency is?
(255) All of the above REF: Robbin's 7th ed p. 913 Alpha 1 antitrypsin deficiency: Due to protease inhibitor deficiency Increased neutrophill elastase Neonatal cholestasis may occur, Hepatocellular carcinoma may also develop Pulmonary disease may occur in form of emphysema Gene located on chromosome 14
Deficiency of protease inhibitor
Autosomal recessive
May cause cholestatic jaundice
All of the above