True about estrogen:
All C18 steroids, including estrone, estradiol, and estriol, are commonly referred to as estrogens. Estriol is a weak estrogen; it is an oxidative product derived from both estradiol and estrone, with the conversion occurring mainly in the liver. The estrogenic potency of b-estradiol is 12 times that of estrone and 80 times that of estriol Estradiol-17b is also one of the most potent regulators of osteoblast and osteoclast function. Estrogen promotes survival of osteoblasts and apoptosis of osteoclasts, thereby oring bone formation over resorption.
Inhibits osteoblast
Decreases expression of LDL receptors
C19 steroid
Estradiol is most potent among estradiol, estratriol and estrone
Female Reproductive System