Most impoant cause of interstitial nepliritis is -
Acute Interstitial nephritis is far more often encountered as an allergic reaction to drug. Drugs causing AIN - Antibiotics (sulfonamides, vancomycin, erythromycin, rifampin, ethambutol, acyclovir) NSAIDS Diuretics (rarely thiazides, loop diuretics, triamterene) Anticonvulsants(phenytoin,valproate,carbamazapine,phenobarbitol PPI'S Ref:Harrison 20 th edition pg no 2157
Drugs
Infection
Malignancy
Dehydration
Kidney