Breast conservation surgery is contraindicated in
.Contraindications * Tumour > 4 cm * Positive axillary nodes > N1 * Tumour margin is not free of tumour after breast conservative surgery needs MRM * Poorly differentiated tumour * Multicentric tumour * Tumour/breast size ratio is more (centeral tumour) * Tumour beneath the nipple * Extensive intraductal carcinoma Ref; (page no;553 ) 5th edition of SRB&;S manual of Surgery
Tumor > 4 cm
Multicentric tumor
Axillary LN involvement
All of the above
Endocrinology and breast