Inhibition of 5-lipooxygenase is useful in:
Ans. (B) Bronchial asthma(Ref: KDT 8th/e p248, 249)Leukotrienes are potent bronchoconstricting agents. These agents play a major role in the pathogenesis of bronchial asthma. The drugs acting by inhibiting their synthesis (i.e. lipoxygenase inhibitors) or action (Cys-LT receptor antagonists), are useful in the prophylaxis of bronchial asthma.
Cardiac failure
Bronchial asthma
Hepatic failure
Arthritis
Asthma