All of the following statements about paneth cells are true, except -
Foamy appearance or frothy cytoplasm is a feature associated with the presence of lipid/mucinous material in the cell cytoplasm. It is seen in mucous secreting goblet cells or lipid phagocytizing macrophage eg Touton giant cell (but not in paneth cells).
Paneth (zymogen) cells are rich in zinc, rough endoplasmic reticulum (RER) and secretory granules containing lysozyme, defensins or cryptidins such as TNF-a. It exceptionally migrate towards the base of the crypt of Lieberkuhn instead of going towards the tip of villi.
Rich in Rough Endoplasmic reticulum
Rich in zinc
Contain Lysozyme
Foamy appearance