Paralysis of 3rd, 4th, 6th nerves with involvement of Ophthalmic division of 5th nerve, localizes the lesion to-
*Paralysis of 3rd, 4th, 6th nerve and involvement of Ophthalmic division of 5th nerve -> cavernous sinus thrombosis. *Paralysis of 3rd, 4th, 6th nerve, Ophthalmic division of 5th nerve plus optic nerve signs -> orbital apex syndrome. Ref: Khurana 7th/e p.428
Cavernous sinus
Apex of orbit
Brainstem
Base of skull
Diseases of orbit, Lids and lacrimal apparatus