A 40-year-old immunocompromised patient presented with complaints of dysphagia. Upper GI endoscopy showed multiple serpiginous ulcers in the distal esophagus. Biopsy from the esophagus showed the following. What is the diagnosis?
Ans. b. CMVRef: Robbins and Cotran Pathologic Basis of Disease 9th Ed; Page No-359VirusRoute of transmissionClinical significance| NotesCMVCongenital transfusion, sexual contact, saliva, urine, transplantMononucleosis ([?] Monospot) inImmunocompetent patients; infection in immunocompromised, especially pneumoniain transplant patients; esophagitis; AIDS retinitis ("cytomegalovirus"): hemorrhage, cotton-wool exudates, vision loss Congenital CMVInfected cells have characteristic "Owl eye" inclusionsLatent in mononuclear cellsExtra MileViral CytopathogenesisInclusion bodiesVirusIntracytoplasmic (Negri bodies)RabiesIntracytoplasmic acidophilic(Guarnieri) PoxvirusesIntranuclear (Owl eye)Cytomegalovirus (CMV)Intranuclear (Cowdry)Herpes simplex virusSubacute sclerosing panencephalitis (measles) virusSyncytia formationHerpes viruses Varicella-zosterParamyxoviruses (measles, mumps, rubella and respiratory syncytial virus) HIV
Candida
CMV
Herpes
Eosinophilic esophagitis
Infectious Disease