Drug of choice for treatment of gastrointestinal stromal tumors is:
Ans: B (Imatinib mesylate) Ref: Goodman & Gillman, The pharmacological basis of therapeutics, 12th edition, Pg No. 1732-1734.Explanation:Imatinib mesylate is used in the treatment of (Approved indications)Chronic phase of CIVILGIST- Gastrointestinal Stromal tumorChronic Myelomonocytic leukemiaHypereosinophilic syndromeDermatofibrosarconia protruberanceProgressive plexiform neurofibromatosisIt is also tried in (Experimental and Not approved for routine use)Systemic MastocytosisPulmonary hypertensionAlzheimer' s diseaseLowering or reversing opioid toleranceDesmoid tumor
Rituximab
Imatinib mesylate
Anagrelide
Denileukin diftitox
Anti-Neoplastic Agents