In congenital dystrophic variety of epidermolysis bullosa, mutation is seen in the gene coding for?
In scarring dystrophic types, blisters developed beneath the lamina densa, in association with rudimentary or defective anchoring fibrils. Dystrophic epidermolysis bullosa is an inherited disease resulting from mutations in the COL 7A1 gene that encodes type 7 collagen Ref: Pathologic basis of disease (Robbins and cotran)7th edition, page no.1263
Laminin 4
Collagen type 7
Alpha 6 integrin
Keratin 14
dermatology and infectious disease