Leptocyte in blood smears seen in?
Ans. (b) Thalassemia(Ref: Robbins 9th/pg 649-652)Leptocytes are flattened red cells in which the volume-to- surface area ratio is decreased. Seen in iron deficiency anemia and thalassemia in which the red cells with a low mean cell hemoglobin (MCH) and mean cell volume (MCV) are unusually resistant to osmotic lysis.
Sickle cell anemia
Thalassemia
Post splenectomy
Uremia
Misc. (R.B.C)