Cold lesion on bone scan suggest:
Ans: B. Osteoclastic activity:cold uptake Ref: Internet Source: Explanation: Interpretation of Bone scans Regional Hyperactivity may be due to: Normal bone growth and remodeling Increased Blood Flow (trauma, heterotopic ossification) Reactive osteoblastic activity (active infections, tumors) Reparative bone process (healing fractures, tumors, infections) Hyper-metabolic activity (metabolic disorders) They induce an increase in blood flow and osteoblastic activity.which enhance Ca / Phosphate local accretion into the hydroxyapatite matrix Cold Spots may be caused by: Malignant Tumors Lung (2-4%) Breast (5%) Renal (10%) Neuroblastomas (bone marrow mets) Thyroid (most cases) Multiple Myeloma (most cases) Bone Abscesses (they are surrounded by activity) Bone ischemia (AVN, sickle cell etc) Hemangiomas (normal or decreased activity)
Osteomyelitis
Lytic lesion
Osteoblastic Lesion
Sequestrum
Imaging of Musculoskeletal Tumors