The term "tumour progression" means ?
Ans. is `d' i.e., Sequential appearance of features of increasing malignancy o Malignant neoplasm has several characterstics, that are acquired in a stepwise fashion, a phenomenon called tumor progression. o The natural history of most malignant tumors has following four phages ? Malignant change in the target stem cell --> Due to genetic or/and environmental factors stem cell is transformed into tumor cell a process is known as transformation and proliferation. Growth and proliferation of transformed cell Local invasion Metastasis
Spread of cancer to distant site
Rate of growth of tumour
Ability of cancer cells to resemble their normal counterpa
Sequential appearance of features of increasing malignancy