Metabolism of a drug primarily results in
Ref-Katzung 10/e p50 After metabolism most of the drugs become inactive and their excreted through the kidney. Lipids soluble drugs wil be reabsprbed whereas water soluble drugs are easily excreted.thus, metabolism of drugs helps in the conversion of liquid soluble drugs to water soluble metabolites
Activation of the active drug
Conversion of prodruv to active metabolite
Conversion of lipid soluble drugs to water soluble metabolites
Conversion of water soluble drugs to lipid solible metabolites
Other topics and Adverse effects