Histology of Alpo syndrome -
Ans. is 'a' i.e., Foamy cells in interstitiumHistological characteristics of Alpo - syndrome :o Diffuse basement membrane thinningo Foam cell in interstitium -4 Due to accumulation of neutral fat and mucopolysaccharideo In advanced stage there is focal or global glomerulosclerosis.o Vascular sclerosiso Tubular atrophyo Interstitial fibrosiso The GBM shows irregular foci of thickening alternating with thinning, with pronounced splitting and lamination of the lamina densa, often with a distinctive basket - weave appearance.
Foamy cells in interstitium
Foamy cells in tubular epithelial cells
Thickening of GBM > 100 nm
All