What would tend to decrease GFR by more than 10% in a normal kidney?
50% reduction in efferent aeriolar resistance would cause a large decrease in GFR--greater than 10%. A decrease in renal aery pressure from 100 to 85 mm Hg would cause only a slight decrease in GFR in a normal, autoregulating kidney. A decrease in afferent aeriole resistance, a decrease in plasma colloid osmotic pressure, or an increase in the glomerular capillary filtration coefficient would all tend to increase GF
Decrease in renal aerial pressure from 100 to 85 mm Hg
50% decrease in afferent aeriolar resistance
50% decrease in efferent aeriolar resistance
50% increase in the glomerular capillary filtration coefficient
Excretory System (Kidney, Bladder) Acid-Base Balance