A patient ingested some unknown substance and presented with myoclonic jerks, seizures, tachycardia and hypotension. ECG shows a hea rate of 120/min. The aerial blood revealed a pH of 7.25, pCO2of 30mm Hg and bicarbonate ions are 15mmol/L. The most likely poisonous agent is:
Ref: KDT 8TH ED. Features are typical of tricyclic antidepressant poisoning. TCAs posses anticholinergic activity that can result in tachycardia. These agents can lead to metabolic acidosis (pH<7.4, HCO3<24mmol/L). Seizures and myoclonic jerks are other features of TCA poisoning.
Amanita phylloids
Ethylene glycol
Imipramine
Phencyclidine
Central Nervous system