A 25 year drug addict is brought to hospital in an intoxicated state. History suggests cocaine misuse, what is the effect of cocaine on blood vessels?
Cocaine act as a vasoconstrictor by blocking re uptake of norepinephrine at sympathetic nerve endings.Coronary aery constriction causes myocardial infarction and with it the risk of cardioembolic stroke.Systemic aery constriction causes acute hypeension, predisposing to rupture of underlying vascular malformations or aneurysms.Cerebral aery constriction causes cerbral ischemia.
Vasoconstrictor
Vasodilator
Vasoineffective
First constrict then dilates