True about acute ITP
ITP is proposed to be secondary to antibodies directed against the platelate glycoprotein 2b/3a complex. mmune thrombocytopenia (ITP) is a disorder that can lead to easy or excessive bruising and bleeding. The bleeding results from unusually low levels of platelets -- the cells that help blood clot. Formerly known as idiopathic thrombocytopenic purpura, ITPcan cause purple bruises, as well as tiny reddish-purple dots that look like a rash. Children may develop ITP after a viral infection and usually recover fully without treatment. In adults, the disorder is often long term. If you don&;t have signs of bleeding and your platelet count isn&;t too low, you may not need any treatment. If your symptoms are more severe, treatment may include medications to boost your platelet count or surgery to remove your spleen. Reference : Ghai essential of pediatrics, eighth edition, p.no:351
More common in female
Specific anti platelet antibodies detected
Viral infection predisposes as seen after vaccination
80% cases transforms to chronic
Hematology