Which of the followign drugs require dose adjustment in renal failure?
Ans. (C) Streptomycin(Ref: Katzung 10/e p835 KDT 8/e p746)Streptomycin is an aminoglycoside and require dose adjustment in renal failure whereas doxycycline, rifampicin and cefoperazone are secreted in bile and do not require dose adjustment in renal failure.
Cefoperazone
Doxycycline
Streptomycin
Rifampicin
Chemotherapy: General Principles