Streptokinase and urokinase are contraindicated in
Intracranial tumours (ICT) are considered an absolute contraindication for thrombolysis because of their association with spontaneous ICH, although no such cases have been repoed in connection with lytic treatment Absolute contraindications for fibrinolytic use in STEMI include the following: Prior intracranial hemorrhage (ICH) Known structural cerebral vascular lesion. Known malignant intracranial neoplasm. Ischemic stroke within 3 months. Suspected aoic dissection. Active bleeding or bleeding diathesis (excluding menses) Ref Harrison20th edition pg 2234
Intracranial malignancy
Pulmonary embolism
AV fistula
Thrombophlebitis
C.N.S