The most impoant source of histamine
ref Robbins 8/e p57,9/e p83 Histamine is synthesized in all tissues, but is paicularly abundant in skin, lung and gastrointestinal tract. Mast cells, which are present in many tissues, are a prominentsource of histamine, but histamine is also secreted by a number of other immune cells.
Mast cells
Eosinophil
Neutrophils
Macrophages
General anatomy