Which one of the following can be homologous substitution for isoleucine in a protein in sequence?
Ans. C. ValineConservative SubstitutionOne amino acid replaced by another amino acid of similar characteristicsExamples of homologous substitution is shown in the given table below.Hydrophilic, AcidicAspGlu Hydrophilic, BasicHisArgLys Polar, UnchargedSerThrGlnAsn HydrophobicAlaPheLeuIleValProNonconservative (Nonhomologous) SubstitutionOne amino acid replaced by another amino acid of different characteristics
Methionine
Aspartic acid
Valine
Arginine
Proteins and Amino Acids