HPV causes which change in cervical epithelium
Ans. is 'c' i.e., Immortalization of epithelial cells o HPV selectively infects the epithelium of skin and mucous membrane and may immortalize the keratinocytes leading either asymptomatic infection, or warts or neoplasia.o Products of E-genes (E6, E7) are related to immortalization or malignant transformation of keratinocytes by interfering with p53 and Rb genes, respectively.
Induction of apoptosis
Induction of necrosis
Immortalization of epithelial cells
By stimulating telomerase
Virology