Cause for caseous necrosis in TB is
Caseous necrosis is seen in tuberculosis and systemic fungal infections (like histoplasmosis) because of the presence of high lipid content in the cell wall in these organisms. So, there is cheese like appearance of the necrotic material ref robbins basic pathology 9th ed page 10
Hydrolytic enzymes
Mycolic acid
High lipid content
Hydrophobic changes by bacterial wall
General pathology