Which of the following is defective in renal glycosuria:
Renal Glycosuria (also called Familial Renal Glucosuria or Glycosuria ) Blood glucose is normal, But still Glucose appears in urine. It is due to defect/mutation in SGLT-2, which is major glucose transpoer (90% glucose reabsorption) present in kidneys for the reabsorption and transpo of Glucose (see fig below). Mutation in SGLT-1 (10% glucose reabsoption) leads to glucose-galactose malabsorption
GLUT- 1
GLUT- 2
SGLT- 1
SGLT- 2
Glucose Transpo