Tangier disease is characterised by which of the following lipid abnormalities?
Tangier disease is a very rare autosomal dominant form of extremely low plasma HDL-Cholesterol caused by mutations in the gene encoding ABCA1. Ref: Harrisons Principles of Internal Medicine, 18th Edition, Page 3154
Extremely low circulating level of plasma cholesterol
Low level of LDL but high HDL level
Extremely low level of triglycerides
Very high level of triglycerides