Which of the following statement regarding gas gangrene is TRUE?
Gas gangrene is a rapidly developing and a spreading infection caused by the toxin producing clostridial species namely, Clostridium perfringens ( formerly known as C. welchii). It is highly fatal if left untreated and accompanied by profound toxicity. If the oxidation-reduction potential in a wound is sufficiently low, C perfringens spores can germinate and then multiply, elaborating alpha-toxin. The process passes along the muscle bundles, producing rapidly spreading edema and necrosis as well as conditions that are more orable for growth of the bacteria. As the disease progresses, increased vascular permeability and systemic absorption of the toxin and inflammatory mediators leads to shock. Ref: Oxford Textbook of Medicine, Vol 1 By D. A. Warell, Timothy M. Cox, Page 553
It is due to Clostridium Botulinum infection
Clostridial species are gram-negative spore forming anerobes
The clinical features are due to the release of protein endotoxin
Gas is invariably present in the muscle compaments