Imatinib mesylate used in the treatment of GIST is a inhibitor of
Imatinib mesylate used in the treatment of GIST ( GastroIntestinal Stromal Tumours) is a c-kit(transmembrane receptor tyrosine kinase) tyrosine kinase inhibitor. GIST is rare but most common nonepithelial small bowel tumours. More than 95% show c-kit mutation. Reference : page 877 SRB's manual of surgery 5th edition
IL-12
TNF-x
Tyrosine kinase
VEGE
Urology