In which of the following enzyme does selenium act as a cofactor?
Glutathione peroxidase contains selenium as a prosthetic group. In erythrocytes and other tissues, it catalyses the destruction of hydrogen peroxide and lipid peroxidase, protecting membrane lipids and hemoglobin against oxidation. Must know: Some other Co-factors that have been asked: Cofactor for carbonic anhydrase: Zn Cofactor for tyrosinase: Cu Cofactor for cytochrome oxidase Cu Cofactor for xanthine oxidase: Mo Cofactor for transamination reaction: Pyridoxine Cofactor for superoxide dismutase: Mn Ref: Bender D.A., Mayes P.A. (2011). Chapter 21. The Pentose Phosphate Pathway & Other Pathways of Hexose Metabolism. In D.A. Bender, K.M. Botham, P.A. Weil, P.J. Kennelly, R.K. Murray, V.W. Rodwell (Eds), Harper's Illustrated Biochemistry, 29e.
Glutathione peroxidase
Cytochrome oxidase
Cytochrome reductase
Xanthine oxidase