Which of the following statements is not true about rifabutin as compared to rifampicin?
Ans. (B) It is more effective for newly diagnosed TB as compared to rifampicin(Katzung 13th/817,820) RifampicinRifabutinHalf lifeShorterLongerCYP inhibition (drug interactions)MarkedWeakEfficacy against Mycobacterium tuberculosisMoreLessEfficacy against MACLessMoreHepatotoxic potentialPresentAbsent
It has longer half-life than rifampicin
It is more effective for newly diagnosed TB as compared to rifampicin
It has lesser incidence of drug interactions as compared to rifampicin
It is more effective against MAC as compared to rifampicin
Chemotherapy: General Principles