The tubuloglomerular feedback is mediated by:
C i.e. Sensing NaC1 concentration in the macula densa'To perform the function of auto regulation, the kidneys have a feed back mechanism (tubuloglomerular feed back) that links changes in sodium chloride concentration at the macula densa (tubular component) with the control of renal aeriolar resistance. (glomerular component).
Sensing of Na+ concentration in the macula densa
Sensing of Cl+ concentration in macula densa
Sensing NaCl concentration in the macula densa
Opening up of voltage gated Na+ channels in afferent aeriole