The following statements regarding streptokinase are true, except:
Streptokinase is a 47-kDa protein produced by beta-hemolytic streptococci. It forms a stable complex with plasminogen, which is not inhibited by antiplasmih. A large loading dose is given intravenously to overcome antibodies that may be formed from prior streptococcal infections. Being a foreign protein it may rarely cause anaphylaxis.
It is a protein produced by streptococci.
Its complex with plasminogen is inhibited by aIpha2-anti plasmin.
It may rarely produce anaphylaxis
It is initially given as a loading dose.