Kaposi sarcoma is characterized by all of the following except: March 2008
Ans. C: Lymphadenopathy is an essential feature in the classical type Kaposi sarcoma is common in patients with AIDS; indeed, its presence is used as a criterion for diagnosing AIDS. There are four types of Kaposi sarcoma: The classic type/chronic KS/ European KS affects elderly men of Mediterranean and Middle European descent and in men in Sub-Saharan Africa. It presents with multiple red to purple skin plaques or nodules, usually in the distal lower extremities; these slowly increase in size and number and spread more proximally. Classic Kaposi sarcoma is rare and unassociated with HIV infection. It most often arises in middle-aged to elderly men of Mediterranean or Jewis descent (less than 10% are women), paicularly if they come from a rural environment. They have a higher than expected rate of diabetes mellitus HIV-associated/epidemic Kaposi sarcoma mainly affects men who have sex with men. Endemic/ African/ Lymphadenopathic Kaposi sarcoma arises in some pas of Africa in children and young adults. It is not associated with HIV. Skin lesion are sparse. Iatrogenic/transplant associated Kaposi sarcoma is due to drug treatment causing immune suppression in the setting of solid organ transplantation.
Usually of the four types
Skin lesion are sparse in African type
Lymphadenopathy is an essential feature in the classical type
AIDS-associated is commoner in homosexual