Drugs that have been found to be useful in compensated hea failure include all of the following except:
BNP analogue (Nesiritide) are used in acute cardiac failure not used in chronic therapy. Compensated hea failure (Chronic CHF): Management: Digitalis (Na+ - K+ ATPase inhibitor) - Inhibit Na+/K+ ATPase--> positive inotropic action. It does not acts as chronotropic agent so no increase in workload on hea and useful in chronic conditions. Aldosterone antagonist: Decreases morbidity/moality. Used to prevent cardiac remodelling along with ACE inhibitors and ARBs. b blockers: These drugs can precipitate acute decompensation of cardiac function but are used in chronic CHF as these decrease moality by reversing LVH.
Na+ K+ ATPase inhibitors
Aldosterone antagonists
BNP analogue
Beta receptor antagonists
Hematology and CVS