Karyotype of klienfelter syndrome is?
Ans. is 'a' i.e., 47XXYKlinefelter syndromeKlinefelter syndrome is the most common chromosomal disorder associated with male hypogonadism and infeility.It is defined classically by a 47, XXY karyotype with variants demonstrating additional X and Y chromosomes.(Other variants can have 48 XXXY, rarely 49 XXXXY or mosaics can be there with some cells containing normal 46,XY and others 47, XXY).Classically, it results from meiotic non-dysjunctionof sex chromosomes (40% during spermatogenesis and 60% during oogenesis). Mostly, non-dysjunctionoccur during lstmeiotic division.
47XXY
45XO
46XXY
45XXX