In an infertile woman, endometrial biopsy reveals proliferative changes. Which hormone should be preferred?
In the question, the infertile woman's endometrial biopsy shows proliferative changes. An endometrial biopsy for infertility is taken on D 25 of the cycle with the aim to rule out anovulation. Normally on these days, an endometrial biopsy should show secretory changes (as ovulation occurs on D-14 and subsequently there is an increase in progesterone levels in the body). But in the case of anovulation, endometrial biopsy shows proliferative changes.
The hormone which should be administered here is obviously progesterone, but that derivative of progesterone which has a weak antiovulatory effect so that it would not further inhibit ovulation.
MDPA
Desogestrol
Norethisterone
None of the above