A 32 year old male patient treated for high blood pressure with thiazides. Which of the following effect can happen in this patient?
The incidence of erectile dysfunction is greater with thiazides than with several other antihypeensive agents (e.g., beta adrenergic receptor antagonists, Ca2+-channel blockers, or angiotensin conveing enzyme inhibitors). Other side effects include, CNS (e.g., veigo, headache, paresthesias, xanthopsia, and weakness) GI (e.g., anorexia, nausea, vomiting, cramping, diarrhea, constipation, cholecystitis, and pancreatitis) Hematological (e.g., blood dyscrasias) Dermatological (e.g., photosensitivity and skin rashes) Fluid and electrolyte imbalanceS (extracellular volume depletion, hypotension, hypokalemia, hyponatremia, hypochloremia, metabolic alkalosis, hypomagnesemia, hypercalcemia, and hyperuricemia) Increase in plasma levels of LDL cholesterol, total cholesterol, and total triglycerides Ref: Reilly R.F., Jackson E.K. (2011). Chapter 25. Regulation of Renal Function and Vascular Volume. In L.L. Brunton, B.A. Chabner, B.C. Knollmann (Eds), Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e.
Hyperkalemic paralysis
Hypouricemia
Hypolipidemia
Impotence