Which of the following enzyme require NAD as a cofactor?
a-Ketoglutarate dehydrogenase catalyse the oxidative decarboxylation of alpha ketoglutarate into succinyl CoA. It requires cofactors such as NAD, FAD, lipoic acid, TPP, CoASH and Magnesium. Some of the enzymes requiring NAD are: Lactate dehydrogenase Glyceraldehyde 3 phosphate dehydrogenase Pyruvate dehydrogenase Beta hydroxyl acyl CoA dehydrogenase Glycerophosphate dehydrogenase Mitochondrial isocitrate dehydrogenase Ref: Biochemistry By S. C. Rastog, 2nd Edition, Page 241; Textbook of Biochemistry By D M Vasudevan, 3rd Edition, Page 271
Citrate Synthase
Isocitrate Dehydrogenase
a-Ketoglutarate dehydrogenase
Succinate Thiokinase