All of the following are true for patients of UC associated with primary sclerosing cholangitis except
Patients with PSC and UC typically have a more quiescent disease course The risk for colon cancer in these patients is up to five times greater than in patients with ulcerative colitis alone. These tumors are more likely to arise proximal to the splenic flexure PSC is progressive and ultimately fatal unless liver transplantation is undeaken. Colectomy has no effect on the course of PSC Ref: Sabiston 20th edition Pgno :1508-1509
They may develop biliary cirrhosis
May have raised alkaline phosphatase
Increased risk of hilar cholangiocarcinoma
PSC reves after a total Colectomy
G.I.T