The most characteristic and frequent feature of chronic rheumatic hea disease is the development of
Rheumatic fever (RF) produces both acute and chronic manifestations. Acute RF produces a pancarditis of all three layers of the hea. It is manifested by myocarditis, which is characterized histologically by the Aschoff body; pericarditis, which is referred to as "bread-and-butter" pericarditis; and verrucous endocarditis. In contrast to acute RF, chronic RF produces damage to cardiac valves. The mitral valve is most commonly involved, followed by the aoic valve. The stenotic valve has the appearance of a "fish mouth" or "buttonhole." An additional finding in chronic RF is a rough poion of the endocardium of the left atrium, called a MacCallum's patch. Reference: Robbins & Cotran Pathologic Basis of Disease, 9edition.
Vegetations on the endocardium
Aschoff bodies within the myocardium
Incompetence of the pulmonic valve
Stenosis of the mitral valve
Cardiovascular system