Which of the following statements about stavudine is accurate?
Stavudine is an NI that is responsible for maximum peripheral neuropathy. It is a thymidine analogue which acts in the same way as Zidovudine. Because of long term serious metabolic complications like lipodystrophy, lactic acidosis and peripheral neuropathy stavudine is no longer employed in WHO as well as NACO regimens.
Bone marrow suppression is dose limiting
It causes marked neurotoxicity
It inhibits HIV protease
It is a non-nucleoside reverse transcriptase inhibitor
Anti-HIV Drugs