All are true regarding cryptococcal infection, except
The disease is more common in an immunocompromised host. 4 serological types of cryptococcal capsular polysaccharide A, B, C and D have been identified. Demonstration of capsular antigen by precipitation can sometimes be valuable for diagnosis of cryptococcal meningitis when the CSF is negative by smear and culture. As the disease is more common in immunocompromised patients, antibodies are not protective. Ref: Textbook of Microbiology, Ananthanarayan and Paniker; 9th edition
Occurs in immunodeficient states
Capsular antigen in CSF is a rapid method of detection
Anticapsular antibody is protective
Urease positive
mycology