Neostigmine antagonizes non depolarising blockade by all of the following mechanism except
Refer Katzung 10/e p 436 Neostigmine is an anti cholinerasterase. It inhibits the breakdown of ACh at the mother end plate This results in increased activity of ACh that causes depolarization of motor end plate by opening Na+channels . It posseses some direct agonistic activating on NM receptors resulting in depolarization
Decreasing the breakdown of acetyl choline at the motor end plate
Preventing the K+efflux
Increasing the release of acetyl choline at the motor end plate
Depolarization at the motor end plate
Anesthesia