A 40-year-old male with paresthesia and numbness of face, perioral area, limbs, muscle weakness in the limbs, chest pain, palpitations, nausea, vomiting, abdominal pain, and diarrhea. On examination, tachycardia and hypotension were observed. Patient gave a history of consuming some unknown plant. Which of the following plants did the patient most likely consume: -
This is a case of Aconite poisoning. Aconitine and related alkaloids found in the Aconitum species are highly toxic cardiotoxins and neurotoxins. The cardiotoxicity and neurotoxicity of aconitine and related alkaloids are due to their actions on the voltage-sensitive sodium channels of the cell membranes of excitable tissues, including the myocardium, nerves, and muscles. Aconite roots contain aconitine, mesaconitine, hypaconitine, and other Aconitum alkaloids, which are known cardiotoxins and neurotoxins Image A shows flower of Datura. Image B shows root of Aconite Image C shows leaves of cannabis Image D shows flower of Nerium.
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