Neuroblastoma differs from Wilms tumor by all, EXCEPT:
Neuroblastoma is the third most common pediatric malignancy and accounts for approximately 10% of all childhood cancers. Wilms' tumor is the most common primary malignant tumor of the kidney in children. Wilms tumour invades Aoa and IVC. Whereas Neuroblastoma does not invade these structures. The inferior vena cava needs to be evaluated by ultrasonography with Doppler flow in Wilms tumor for the presence and extent of tumor propagation. Plain radiographs may show stippled calcifications in neuroblastoma (about 85%) which are generally less common and less prominent in wilms tumour. The most common sites of metastases of neuroblastoma are bone, bone marrow, lymph nodes, liver, and subcutaneous tissue. It has a predilection for metastasis to the skull, in paicular the sphenoid bone and retrobulbar tissue. Bone and brain metastases are extremely uncommon in Wilms tumor. Ref: Hackam D.J., Grikscheit T.C., Wang K.S., Newman K.D., Ford H.R. (2010). Chapter 39. Pediatric Surgery. In F.C. Brunicardi, D.K. Andersen, T.R. Billiar, D.L. Dunn, J.G. Hunter, J.B. Matthews, R.E. Pollock (Eds), Schwaz's Principles of Surgery, 9e.
Calcification
Aoa and IVC arc not eroded but pushed aside
Age group
Bone metastasis