Function of leptin is-
Ans. is 'a' i.e., Reduce food intake Leptin* Leptin is a protein hormone produced by fat cells. It acts on hypothalamus to reduce food intake, decrease lipogenesis and increase lipolysis, thereby reducing the body fat stores.* The effect of leptin on appetite is mediated through a-MSH (a-melanocyte stimulating hormone), a pro- opiomelanocortin (POMC) derivative. Leptin acts by increasing the synthesis of POMC which is converted into a-MSH. a-MSH acts through melanocortin-4 receptors to depress appetite.* Leptin also inhibits the secretion of Agouti-related peptide (AgRP), a neuropeptide that increases food intake.* Plasma leptin levels are proportional to the amount of body fat and are therefore higher in women and obese individuals.
Reduce food intake
Stimulation of AgRP
Decrease lipolysis
All of the above
G.I.T.