Organophosphate inhibits -
Ans. is 'b' i.e., Esteratic site of AchEs Acetylcholinesterase has two sites: i) Catalytic or esteratic site -9 Active site ii) Anionic site It is quite obvious that to inhibit the action of acetylcholinesterase the active site has to be inhibited and it is esteratic site: i) Organophosphates phosphorylate esteratic site. Carbamates carbomylate esteratic site.
Anionic site ofAchEs
Esteratic site ofAchEs
Ach
None