On colonoscopy which of the following is highly malignant -
• Also referred to as Bannayan-Zonana syndrome, Ruvalcaba-Riley smith syndrome, and Bannayan-Riley-Ruvalcaba syndrome.
• Characterized by hamartomatous polyposis and OLD HM-2.
OLD HM-2 :
• Ocular abnormalities, Lipomas, Developmental abnormalities.
• Hashimoto’s thyroiditis, Hyperpigmentation of penis.
• Macrocephaly, Mental retardation.
• No increased risk of colorectal carcinoma, other gastrointestinal or extraintestinal malignancy.
Single pedunculated polyp
Multiple flat polyp about hundreds
Multiple pedunculated polyp
Solitary flat polyp