Which NSAID can cause hyperuricemia?
ASPIRIN can cause hyperuricemia depending on dose used. At low doses :1-2g/day -decrease uricacid excretion and hence cause hyperuricemia. It also blocks the effects of probencid and other uricosuric drugs. Intermediate doses:2-3g/day-No effect Large doses:>5g/day-uricosuric 1st most commonly used NSAID in hyperurecemia ahritis (gout) is NAPROXONE 2nd most commonly used is IBUPROFEN ref : maheswari th ed
Tolmetin
Ibuprofen
Aspirin
Naproxen
Joint disorders