Effectiveness of blood brain barrier is by
The blood-brain barrier is formed by endothelial cells of the capillary wall, astrocyte end-feet ensheathing the capillary, and pericytes embedded in the capillary basement membrane. Ref: guyton and hall textbook of medical physiology 12 edition page number:671,672,673
Thick basement membrane
Tight arrangement of astrocytes
Tight endothelial function
Microglial cell
Nervous system