Which of the following agents enhances the bioavailability of levodopa in patients with Parkinson's disease:
Entacapone & tolacapone which cones under COMT INHIBITORS enhance & prolong the therapeutic effect of levodopa-carbidopa in advanced & fluctuating PD . Ref: KD Tripathi 8th ed.
Amantadine
Ropinirole
Entacapone
Selegiline
Central Nervous system