All are true about Barrett's esophagus, EXCEPT:
Barrett's Esophagus: 1. Barrett's esophagus is specialized columnar metaplasia that replaces the normal squamous mucosa of the distal esophagus. 2. It is a major risk factor for adenocarcinoma of the esophagus and is readily detected endoscopically. 3. A screening endoscopy for Barrett's esophagus may be considered in patients with a chronic history (>10 year) of GERD symptoms. 4. Endoscopic biopsy is the gold standard for confirmation of Barrett's esophagus. ALSO KNOW: Endoscopic therapies such as endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), photodynamic therapy (PDT), and radiofrequency ablation (RFA) are effective modalities for treatment of high-grade dysplasia and intramucosal cancer in Barrett's esophagus. Ref: Harrison, Edition-18, Page-2419.
Specialised columnar metaplasia
Major risk factor for adenocarcinoma esophagus
Screening endoscopy is required in all patients with GERD symptoms
Endoscopic biopsy is the gold standard for confirmation