1730. A nine month old boy of Sindhl parents presented to you with complaints of progressive lethargy, Irritability & pallor since 6 months of age. Examination revealed severe pallor. Investigation showed Hb-3.8 mg%; MCV-58fl; MCH-19.4 pg/ cell. Blood film shows osmotic fragility Is normal (target cells and normoblasts). X-ray skull shows expansion of erythroid marrow. Which of the following Is the most likely diagnosis
<p>In iron deficiency anemia ,hemoglobin will be mild to moderate but occasionally it may be marked(less than 6g/dL). In peripheral smear,microcytic hypochromic red cells are seen;target cells ,polychromatic cells, normoblasts are seen.MCV will be less than 80fl & MCH less than 27pg. The marrow hypercellularity is increased due to marrow hyperplasia .</p><p>Reference :Harsh mohan textbook of pathology sixth edition pg no 299</p>
Iron deficiency anemia
Acute lymphoblastic anemia
Hemoglobin D disease
Hereditary spherocytosis
Haematology