Which of the following is true about factor V leiden mutation?
Factor V Leiden mutation is hypercoagulable disorder characterized by deep venous thrombosis and pulmonary thromboembolism. Factor V becomes resistant to cleavage by protein C. It occurs due to arginine to glutamate substitution. Factor V deficiency is known as Para hemophilia.
Increased bleeding tendency
Factor V becomes resistant to cleavage by protein C
Arginine to glycine substitution
Deficiency of factor V
NEET 2018