Gigantism is due to:
- Excess GH results in: overgrowth / gigantism during childhood with open epiphysis * After fusion of epiphysis - ACROMEGALY - Features of Acromegaly: Coarse facies large tongue Prognathism(protruded lower jaw) thick skin broad nose headache & visual field defects - Best screening test - IGF 1 levels - TREATMENT: Somatostatin analogues (Octreotide) GH Receptor antagonist (Pegvisomant)
Increased secretion of coisol
Decreased secretion of coisol
Increased secretion of growth hormone
Decreased secretion of growth hormone
Disorders of Pituitary Gland