Which of the following drugs DOES NOT cause Sicca Syndrome?
Sicca syndrome is charecterised by Xerostomia (subjective feeling of mouth dryness) and xerophthalmia (subjective feeling of eye dryness) are the key symptoms in the diagnosis of Sjogren syndrome, occurring in more than 95% of patients. Drugs known to cause sicca syndrome Anticholinergic drugs (atropine, scopolamine) Sympathomimetic drugs (ephedrine) Benzodiazepines Selective serotonin reuptake inhibitors Tricyclic antidepressants Phenothiazines Antihistamines Nicotine Opioids a1 antagonists (terazosin and prazosin) a2 agonists (clonidine) b blockers (atenolol, propranolol) Diuretics Ref: Primary Sjogren syndrome ; BMJ 2012;344:e3821.
Atropine
Nicotine
Olanzapine
Clonidine