Which of the following is the least common site of atherosclerotic lesions
Atherosclerosis is an intima-based lesion composed of a fibrous cap and an atheromatous (literally, "gruel-like") core; the constituents of the plaque include smooth muscle cells, ECMs, inflammatory cells, lipids, and necrotic debris. The impoance of hemodynamic factors in atherogenesis is illustrated by the observation that plaques tend to occur at ostia of exiting vessels, at branch points, and along the posterior wall of the abdominal aoa, where there is turbulent blood flow. In vitro studies fuher demonstrate that nonturbulent laminar flow leads to the induction of endothelial genes whose products protect against atherosclerosis. (Robbins Basic Pathology,9th edition,pg no.338)
Aoic bifurcation
Pulmonary aerial trunk
Common carotid aery
Middle cerebral aery
Cardiovascular system