The best investigation for the diagnosis of amyloidosis is:
The histological examination of the biopsy material is the commonest and confirmatory method for the diagnosis in a suspected case of amyloidosis. The sites for the biopsy can be:- Renal tissue Rectum Abdominal fat aspiration Gingiva. The rectum Q is the best site for taking the biopsy in the options provided. However as per Harrison latest edition, the abdominal fat aspirate is currently the best option for systemic amyloidosis.
Colonoscopy
Rectal biopsy
Upper GI endoscopy
CT scan
Amyloidosis