A 40-year-old male presented with a thyroid swelling and dysphagia. He gave history of on and off watery diarrhea. Biopsy of the lesion is shown. What is your diagnosis?
Ans. (c) Medullary Ca thyroid*Diarrhea in thyroid tumor can be a paraneoplastic syndromes due to VIP in a case of medullary Ca thyroid. Histology demonstrates abundant deposition of amyloid, visible here as homogeneous extracellular material, derived from calcitonin molecules secreted by the neoplastic cells.
Follicular Ca thyroid
Papilllary Ca thyroid
Medullary Ca thyroid
Anaplastic cell Ca Thyroid
Endocrine