True about Hodgkin's lymphoma are all except?
HODGKIN'S LYMPHOMA : - HL arises in lymphoid tissue & spreads to adjacent lymph node areas in a relatively orderly fashion. -Patients commonly present with painless, non-tender, firm, rubbery, cervical or supraclavicular lymphadenopathy and usually some degree of mediastinal involvement. HEPATOSPLENOMEGALY IS A FEATURE BUT NOT ALWAYS PRESENT - Chemotherapy & radiation therapy are both effective in treatment of HL. TREATMENT- A- Adriamycin (Doxorubicin) B - Bleomycin V - Vinblastine D - Dacarbazine
Often localized to single axial group of lymph nodes
Hepatomegaly is always present
Contiguous spread of lymph nodes
Can be cured by Chemotherapy and Radiotherapy
Neoplastic disorders of WBCs