Drug of choice for Juvenile Myoclonic epilepsy is?
Avoiding precipitating events such as alcohol use and sleep deprivation may be useful. However, medical therapy with anti-convulsants is typically needed and well tolerated. The majority of patients can be well-controlled on a single drug, most commonly valproic acid. Other medications that might be used separately or in combination include lamotrigine, levetiracetam, clonazepam, and topiramate. Drug of choice for juvenile myoclonic epilepsy is Sodiumvalproate, benzodiazepines, ACTH . Newer antiepileptics such as topiramate,zonisamide, lamotrigine can be used. Juvenile myoclonic epilepsy is an epilepsy syndrome characterized by myoclonic jerks (quick jerks of the arms or legs), generalized tonic-clonic seizures (GTCSs), and sometimes, absence seizures. The seizures of juvenile myoclonic epilepsy often occur when people first awaken in the morning. Seizures can be triggered by lack of sleep, extreme fatigue, stress, or alcohol consumption. Onset typically occurs around adolesence in otherwise healthy children.The causes of juvenile myoclonic epilepsy are very complex and not completely understood. Mutations in one of several genes, including the GABRA1 and the EFHC1 genes, can cause or increase susceptibility to this condition. Although patients usually require lifelong treatment with anticonvulsants, their overall prognosis is generally good. Reference: GHAI Essential pediatrics, 8th edition
Phenytoin
Lamotrigine
Valpraote
Zonisamide
Central Nervous system