Many signaling pathways involve the generation of inositol trisphosphate (IP3) and diacylglycerol (DAG). These molecules
IP3 DAG are secondary messengers derived from PIP2 they are present in the cell membrane where IP2 crosses the cell membrane and DAG doesnot. Ref: KD Tripathi 8th ed.
Are first messengers
Activate phospholipase C
Are derived from PIP2
Can't activate calcium calmodulin-dependent protein kinases directly or indirectly
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