Combination of amoxicillin with clavulanic acid is active against all the following organisms except
MRSA occurs due to altered Pencillin binding proteins There fore cannot be replaced by beta lactamase inhibitor like clavulanic acid Refer GG 1497
MRSA
Pencillinase producing staph aureus
Pencillinase producing N.gonorrhea
Beta lactamase producing E. Coli
Chemotherapy