Classical markers for Hodgkin&;s disease-
Immunophenotyping of RS cells reveals monoclonal lymphoid cell origin of RS cell from B cells of the germinal centre in most subtypes of Hodgkin&;s disease. RS cells in all types of HD, except lymphocyte predominance type express immunoreactivity for CD15 and CD30.Therefore they ard considered as the classical markers for HD. REFERENCE; Harsh Mohan textbook of pathology,7th edition.Pg no.349
CD 15 and CD 30
CD 15 and CD 22
CD 15 and CD 20
CD 20 and CD 30
Haematology