Why is citrate phosphate dextrose (CPD) is better than acid citrate dextrose (ACD) for storage of blood?
Citrate dextrose phosphate adenine (CDPA-1) helps in improving ATP synthesis during storage, thus increasing the shelf-life of storage up to35 days. Disadvantage of CDPA-1:Increases uric acid stone formation. Citrate phosphate dextroseImproves oxygen transpo Shelf life of the blood after adding above chemicals: - Acid citrate dextrose -> 21 days Citrate phosphate Dextrose -> 21 days Citrate phosphate Dextrose Adenine -> 35 days Saline Adenine Glucose Mannitol -> 42 days.
Because it is less acidic
Improves oxygen transpo
Hypeonicity of blood
More citrate ions
NEET Jan 2020