Which of the following enzyme of Heme synthesis is located in mitochondria?
First reaction and the last 3 reactions of heme synthesis take place in the mitochondria. The rest of them takes place in cytosol. Figure: Heme synthesis occuring in mitochondrion & cytosol
ALA synthase
ALA dehydratase
Uroporphyrinogen I synthase
Uroporphyrinogen decarboxylase
HAEM synth and porphyrias