Which of the following adverse effects is characteristically associated with methysergide?
All ergot derivatives can cause fibrosis on long term use. Due to risk of retroperitoneal fibrosis, methysergide should never be given continuously for more than 6 months.
Pulmonary hypeension
Retroperitoneal fibrosis
Hepatotoxicity
Ischemic hea disease
Histamine, 5-HT and PGs