All of the following statements are true regarding craniopharyngioma, except:
Craniopharyngioma Arise from vestigial remnants of Rathke's pouch. Slow-growing benign tumors Accounts 1% to 5% of intracranial tumors. Minority of these lesions occurs within sella, but most are suprasellar with/ without intrasellar extension. Adamantinomatous craniopharyngioma - Abnormalities of WNT signaling pathway, activating mutations of gene encoding b-catenin. Papillary subtype is characterized by activating mutations of the BRAF oncogene at codon 600 (V600E).
Origin from Rathke's pouch
Aggressive malignant tumor
Papillary variant of the tumour is associated with BRAF V600E mutation
Adamantinomatous variant is associated with abnormality in WNT/CTNNB1 (b-catenin) pathway
Adrenal Gland