Carbamoyl phosphate synthase - 1 is stimulated by ?
Carbamoyl phosphate synthase-I (CPS-I), a mitochondrial enzyme, catalyzes the formation of carbamoyl phosphate by condensation of CO2 and ammonia.Two molecules of ATP are required for the reaction. CPS-I is the rate limiting enzyme of urea cycle. It is an allosteric enzyme and allosterically activated by N-acetyl glutamate.
ATP
Arginosuccinate
Carbamoyl phosphate
N-acetyl glutamate