True regarding Sjogren's syndrome are all of the following except:
Ans. (b) Males are commonly affectedRef: Bailey 261e p737Sjogren's Syndrome:* Most common in women* Chronic disease characterized by dry eyes, dry mouth (xerostomia) due to immunological destruction of Lacrimal and Salivary glands* Rheumatoid arthritis is commonly associated.* Characterized by lymphocytic infiltration of salivary and lacrimal glands.* Antibodies - SS-A and SS-B are seen in 90%* Parotid enlargement is seen in >50% cases* Lip biopsy is used to diagnose this syndrome (by examining minor salivary glands)
Autoimmune condition
Males are commonly affected
Progressive destruction of lacrimal and salivary gland
No single laboratory investigation is pathognomonic
Salivary Gland