Preformed mediator of inflammation is
Chemical mediators of inflammation Cellular mediatorsPreformed mediators in secretory granulesNewly synthesizedHistamineSerotonin Lysosomal enzymes ProstaglandinsLeukotrienesPlatelet-activating factorActivated oxygen species Nitric oxide Cytokines Plasma mediatorsFactor XII activationComplement activationKinin system Coagulation / fibrinolysis system C3aC5aC3bC5b - 9 (Refer: Robbins & Cotran's - Pathologic Basis of Disease, SAE, 1st edition, Vol I-pg no: 82-85)
Serotonin
Prostaglandin
Dopamine
Leukotrienes
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