All are TRUE about thin basement membrane defect, EXCEPT:
Benign familial hematuria is also referred to as thin basement membrane disease. It is inherited as an autosomal dominant trait Characterised by persistent or recurrent microscopic hematuria, a uniformly thinned GBM, and normal renal function. Proteinuria and episodes of gross hematuria are uncommon. The disease is not associated with extrarenal manifestations Ref: Dan Med Bull 2009; 56:105-52
Also known as benign familial hematuria
Autosomal dominant inheritance
Persistent or recurrent microscopic hematuria
Impaired renal function