Medullary carcinoma thyroid all EXCEPT:March 2013
Ans. B i.e. TSH dependentThe rate of growth of papillary carcinoma thyroid may be stimulated by TSHThyroid medullary Ca/ MTC80% cases are sporadic,20% are familial (MEN-Ha or MEN-Hb),MTC is the first abnormality expressed in MEN-Ha/ Ilb,Stroma of MTC shows material with staining propeies of amyloid,MTC can be diagnosed by demonstrating calcitonin within the MTC cells (on immuno-histochemical studies),Total thyroidectomy is the TOC
Contains amyloid
TSH dependent
Secretes calcitonin
Patients should be screened for RET point mutation on chromosome 10