Xanthochromia of CSF seen in all except:
Ref: Harrison's Principles of Internal Medicine, 18th ed, page 46-1Explanation:Xanthochromia is yellow' discoloration of CSF supernatant. Seen in:SAHJaundiceIncreased proteins (>1.5-2 g/L)Froin's syndrome (spinal subarachnoid block, xanthochromia & excess proteins)Carotene addictionBloody tap Vs SAHBloody tapSAHCSF clears on centrifugationXanthochromic supernatant CSFBlood clears in subsequent tubesUniformly bloody in all the tubesCauses of high CSF protein:Guillian-Barre syndrome (GBS)Spinal tumorsMeningitisMultiple sclerosisAcoustic neuromaAlbumino-cytological dissociation seen in GBS CONTRAINDICATIONS: Patient needs neuroimaging before LP-Altered level of consciousnessPapilledemaFocal neurological deficitNew-onset seizureImmunocompromised stateLocal skin infectionPlatelet count <20,000/cmmCSFNormal ValuesPROTEIN15- 50mq/dLGLUCOSE40-7Dmg.'dLCELLS0-5: L & MPRESSURE5-18 cm H20VOLUME150 mL
Bloody tap
Carotene
Increased antibodies
Increased proteins
C.N.S.