Spastic paraplegia is caused by all of the following, except:
Cord compression due to Cervical spondylosis, sub acute combined degeneration of cord due to vitamin B12 deficiency, and motor neuron disease involving the upper motor neuron's are all established cause for spastic paraplegia. Causes of spastic paraplegia includes: Thrombosis of anterior spinal aery Inflammation of cord: acute transverse myelitis Trauma of the spinal cord: fracture of veebrae, gunshot injury Nutritional: sub acute combined degeneration of the cord, lathyriasis Spinal cord compression: tumor in meninges or cord, caries of spine, syphilitic patchy meningitis Degeneration of the cord: multiple sclerosis, cervical spondylosis, amyotropic lateral sclerosis and syringomyelia Ref: Principles and Practice of Medicine a TB for Students and Practitioners By Prasad, Page 670
Lead poisoning
Cervical spondylosis
Vitamin B12 deficiency
Motor neuron disease