Epstein-Barr virus (EBV) VCA-IgG 1 :80 and EBV antibody to early antigen EA1 :320 suggest which one of the following diseases?
Infectious mononucleosis (IM) may be suspected clinically but it is confirmed serologically. The heterophil antibody test, however, may be negative in up to 15% of adults and 35 to 40% of children. Because IM is caused by Epstein-Barr virus (EBV), a specific test for viral capsid antigen (VCA) of EBV is indicated when heterophil tests are negative. Acute IM is characterized by a VCA-IgM titer, and no VCA-IgG antibody or EBNA. Chronic EBV disease causes elevated VCA-IgG titers as well as high EA antibody titers.
Chronic infectious mononucleosis
Primary syphilis
Scarlet fever
Primary atypical pneumonia
Immunology