About cetirizine all are true except-
Ans. is 'c' i.e., Good CNS penetration Cetrizine* Cetrizine is a 2nd generation anti histaminic* It is a metabolite of hydroxyzine with marked affinity for the peripheral H1 receptors,* It penetrates CNS poorly and has mild sedating effect.* It inhibits release of histamine from mast cells and therefore has been used for urticarial and atopic dermatitis.* It is non - arrhythmogenic.
It is a 2nd generation anti histaminic
It is a metabolite of hydroxyzine
Good CNS penetration
Inhibits release of histamine
Anti Histaminics