After taking ceain medications a patient noticed yellowing of eyes. Which of the following most often causes cholestatic jaundice?
Cholestatic jaundice caused by erythromycin estolate (and rarely by the stearate) appears to be specifically related to the propionyl ester linkage of the 29 position. Thus, a history of cholestatic jaundice during therapy with oral erythromycin estolate is not an absolute contraindication to intravenous therapy with erythromycin gluceptate or lactobionate. Ref: Aoki F.Y. (2005). Chapter 45. Principles of Antimicrobial Therapy and the Clinical Pharmacology of Antimicrobial Drugs. In Hall J.B., Schmidt G.A., Wood L.H.(Eds), Principles of Critical Care, 3e.
INH
Erythromycin estolate
Pyrazinamide
Ethionamide