A term neonate presents with unconjugated hyperbilirubinemia of 18 mg/dl on 29th day. All of the following are common causes, EXCEPT:
Neonatal hepatitis can lead to conjugated hyperbilirubinemia and present at 4-6 weeks of age. Two other groups of disorders are associated with hyperbilirubinemia: (1) Unconjugated hyperbilirubinemia seen in, Breast milk jaundice Blood group incompatibility Lucey-Driscoll syndrome Congenital hypothyroidism Upper intestinal obstruction Gilbe disease Crigler-Najjar syndrome Hereditary spherocytosis Non-spherocytic hemolytic anemia Drug-induced hyperbilirubinemia (2) Conjugated hyperbilirubinemia present in, Dubin-Johnson syndrome Rotor syndrome Biliary atresia Neonatal hepatitis Ref: Sokol R.J., Narkewicz M.R. (2012). Chapter 22. Liver & Pancreas. In W.W. Hay, Jr., M.J. Levin, R.R. Deterding, J.J. Ross, J.M. Sondheimer (Eds), CURRENT Diagnosis & Treatment: Pediatrics, 21e.
Breast milk jaundice
Neonatal hepatitis
G-6PD deficiency
Hypothyroidism