Nitroglycerine is effective when adminsted sublingually because it is
Nitroglycerin is effective when retained sublingually because it is non ionized and has very high lipid solubility.Thus,the drug is absorbed very rapidly. (Ref-Goodman Gillman12th/e p124,125)
non ionized and lipid soluble
ionized and lipid soluble
non ionized and water insoluble
ionized and water soluble
General anatomy