Prostaglandins are derived from :
Prostaglandins are derived from arachidonic acid through the cyclooxygenase (COX) pathway.Two isoforms of COX have been recognized.COX-1 is expressed constitutively, whereas COX-2 is induced by growth factors, tumor promoters, and proinflammatory cytokines.COX catalyzes oxidative cyclization of arachidonic acid to prostaglandin endoperoxide, which is the immediate precursor of prostaglandins, thromoboxane, and prostacyclin
Coicosteroids
Oleic acid
Linoleic acid
Arachidonic acid