Spongiosis is seen in:
ECZEMA - Reaction pattern of inflammatory response of skin characterized clinically in Acute stage- Spongiosis( oozing out lesions) erythema vesiculation Chronic stages - Acanthosis (lichenified lesions) Histopathological features of eczema - Epidermis: 1 Acute phase spongiosis i.e. intercellular edema. 2 Subacute phase Parakeratotic stratum corneum. Acanthotic process stas. Rete ridges broaden and get elongated. 3 Chronic phase Rete ridges broaden and elongate fuher. Hyperkeratosis replaces parakeratosis. Dermis: Vasodilatation in the papillary dermis accompanied by lympho-histiocytic infiltrate. Polymorphs and Eosinophils are seen in Acute eczema .
Acute eczema
Lichen planus
Psoriasis
Pemphigus
Eczema and related disorders