Which antiepileptic drug can lead to this adverse effect:
Ans. (A) PhenytoinThe figure shows the gum hypertrophy which is caused by phenytoinThe mechanism of action of antiepileptic drugsMain mechanismDrugNa Channel blockersPhenytoinCarbamazepineLamotrigineValproateStimulate GABA-BZD Cl channel complesBarbituratesBenzodiazepinesInhibit GABA transaminaseVigabatrinInhibit GAT-1TiagabineAct on SV2ALevetiracetamOpen K+ ChannelsRetigabineBlock NMDA receptorsFelbamateBlock AMPA receptorsPerampanelBlock L type Ca ChannelsEthosuximide
Phenytoin
Carbamazepine
Valproate
Lamotrigine
C.N.S