Crizotinib is used in the treatment of :
Crizotinib inhibits anaplastic lymphoma kinase (ALK), hence used in ALK mutation positive non small cell carcinoma of lungs.
FLT-3 +ve Non small cell carcinoma of lung
ALK +ve Non small cell carcinoma of lung
FLT-3 +ve  Acute myeloid leukemia
BRCA-2 +ve metastatic breast carcinoma