A child suffering from asthma is to be treated with a drug that blocks the synthesis of leukotrienes. What drug would be an appropriate choice
zileuton mech of action:- It is a 5-LOX(lipoxygenase) inhibitor, blocks LTC4/D4 as well as LTB4 synthesis. It therefore has the potential to prevent all LT induced responses including those exeed by activation of cysLT1 receptor. Duration of action of zileuton is sho. side effects:- Hepatotoxicity
Cromolyn sodium
Montelukast
Zileuton
Theophylline
Respiratory system