All are true regarding interleukin-1 except ?
Ans. is 'c' i.e., Inhibit IL-2 production by T-cells Interleukin -1 Also known as leucocyte activating factor (LAF) or B cell activating factor (BAF). Principally secreted by macrophages and monocytes; and epithelial cells. Other sources are B lymphocytes, fibroblasts and endothelial cells. Immunological effects- Activation of T cells for the production of IL - 2. B cell proliferation and antibody synthesis Neutrophil chemotaxis and increased PMN release from bone marrow. Increases body temperature (impoant endogenous pyrogen). Bone marrow cell proliferation Induction of acute phase protein.
Primary source is monocyte-macrophage system
Endogenous pyrogens
Inhibit IL-2 production by T-cells
All are true