Kaolin cephalin clotting time is:
Kaolin cephalin clotting time is the older term to describe activated paial thromboplastin test, which is aimed at detecting the function of intrinsic pathway. In Kaolin cephalin clotting test, kaolin is used as a surface activator, it binds directly to Factor XII resulting in surface activation to XIIa. XIIa cleaves Factor XI to XIa. Cephalin is a phospholipid substitute that replaces platelet phospholipid in the test. Ref: Haematology By Main R. Howard, Peter J. Hamilton, Page 22
Prothrombin Time
Activated paial thromboplastin test
Cephalin is a surface activator
Kaolin is a platelet phospholipid substitute.