Which of the following is False regarding H.Pylori infection :
Answer is A (With chronic infection urease breath test becomes negative) Urease breath test detects H. pylon infection by 'bacterial urease activity' and remains positive till the bacteria has not been eradicated with treatment. Thus urease breath test becomes negative only after eradication of organism following treatment and not with chronic Mfection. Despite a substantial humoral antibody response infection persists indefinitely (persists life long if untreated) Invasive diagnostic test are based on Endoscopic, endoscopy is a diagnostic application. H. pylori produces several virulence factors that have been implicated in the damage of mucosa.
With chronic infection urease breath test become negative
H.Pylori infection remain lifelong if untreated
Endoscopy is diagnostic
Toxigenic strains usually causes ulcer