A 34-year-old, G, P0, presents for genetic counselling at 12 week's gestation. The patient has two sisters and a brother; her father
has haemophilia. Her siblings are not affected, but she has a nephew that is:
Haemophilia is an X-linked recessive disease. These diseases are more common in men than in women.
An affected male will not pass the diseases to his sons, but all daughters will be carriers. X-linked recessive diseases are transmitted from carrier women to affected men.
Autosomal recessive
X-linked inheritance
Mitochondrial inheritance
Multifactorial inheritance