Adult patient presents with generalized lymphadenopathy and blood film shows 70percent immature looking lymphocytes. What should be the next best investigation?
Adult pateint presenting with generalized lymphadenopathy and blood film shows 70percent immature looking lymphocytes is highly suggestive of chronic lymphocytic leukemia. Immunophenotyping can be one of the best ways to differentiate between CLL and other B cell neoplasms.( ref Robbins 9/e p593)
Genotyping/karyotyping
Immunophenotyping
Bone marrow
Peripheral smear study
Haematology