Which among the following is an antibiotic agent that penetrates burn eschar to reach interface with patient's ble tissue ?
Mafenide acetate Antibiotic agent that penetrates burn eschar to reach interface with patient's ble tissue. Disadvantages- Quite painful on any paial thickness areas, and it is a carbonic anhydrase inhibitor that interferes with renal buffering mechanisms. Chloride is retained & metabolic acidosis can occur. For these reasons, silver sulfadiazine is more commonly used in burn centers unless a major problem with burn wound sepsis is present.
Mafenide acetate
Neomycin
Silver nitrate
Silver sulfadiazine
Burns