The most strongly implicated premalignant condition of the oral cavity is
ConditionUsual locationClinical featuresCourseFordyce spotsBuccal and labial mucosaNumerous small yellowish spots just beneath the mucosa; no symptoms; due to hyperplasia of sebaceous glandsbenignErythroplakiaFloor of mouth in men; tongue and buccal mucosa in womenVelvety, reddish plaqueHigh risk for squamous cell cancerMedian rhomboid glossitisMedian posterior poion of tongueCongenital abnormality of tongue with ovoid, denuded areabenignErythema multiformeOral mucosa Intraoral ruptured bullae surrounded by inflammatory areas; lips may show hemorrhagic crustsNot a premalignant condition(Ref: Harrison's 18/e p217, table 32.1-32.4)
Fordyce spots
Erythroplakia
Median rhomboid glossitis
Erythema multiforme
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