Aspirin is used for ischemic heart disease:
Ans. A. Inhibit TXA2 synthesisAspirin is irreversible COX inhibitor. At low dose 40-325mg they act as antiplatelet agent. They inhibit TXA2 synthesis which is platelet aggregator but also inhibit PGI2 which is platelet anti aggrator. But the net effect is TXA2 inhibition.
Inhibit TXA2 synthesis
Inhibit prostacyclin
Inhibit COX 2
Inhibit synthesis of endothelin
Prostaglandins