The highest volume overload in a parturient due to maximum cardiac output is seen:
Ans. d. Immediately after delivery (Ref: Dutta's 6/e p53)The highest volume overload in a parturient due to maximum cardiac output is seen immediately after delivery."Peripheral vasodilation leading to a decrease in systemic vascular resistance is thought to be the first cardiovascular change associated with pregnancy (induced by progesterone). Cardiac output increases in response to this, by 20% at 8 weeks gestation and by up to 40-50% at 20-28 weeks gestation. Labour leads to further increases in cardiac output by 15% in the first stage and 50% in the second stage due to the combination of auto-transfusion of 300-500 ml of blood back into the circulation with each uterine contraction, and sympathetic stimulation caused by pain and anxiety. Cardiac output increases again immediately after delivery due to auto-transfusion of blood via uterine contraction and relief of aortocaval compression. This may increase cardiac output by as much as 60-80%, followed by a rapid decline to prelabour values within 1 hour."- Dutta's 6/e p53Physiological Changes in the Cardiovascular System During PregnancyPeripheral vasodilation leading to a decrease in systemic vascular resistance is thought to be the first cardiovascular change associated with pregnancy (induced by progesterone).Cardiac output increases in response to this, by 20% at 8 weeks gestation and by up to 40-50% at 20-28 weeks gestation.This is achieved predominantly via an increase in stroke volume (due to an increase in ventricular end-diastolic volume, wall muscle mass, and contractility) but also by an increase in heart rate.Labour leads to further increases in cardiac output by 15% in the first stage and 50% in the second stage due to the combination of auto-transfusion of 300-500 ml of blood back into the circulation with each uterine contraction, and sympathetic stimulation caused by pain and anxiety.Cardiac output increases again immediately after delivery due to auto-transfusion of blood via uterine contraction and relief of aortocaval compression. This may increase cardiac output by as much as 60-80%, followed by a rapid decline to pre-labour values within 1 hour.
During second trimester
At term
After a heavy meal
Immediately after delivery
Cardiovascular System