Topical Mitomycin C is useful in treatment of?
Laryngotracheal stenosis treated by serial dilatation using Jackson bronchoscopes. Laser have tendency to recur and hence adjuvant methods are done to decrease the rate of restenosis. Mitomycin C is an example of one of these adjunctive agents. It is a chemical derived from the Streptomyces caespitosus bacterium. It is an alkylating agent which has both antineoplastic and antiproliferative propeies and inhibits fibroblast production and thus prevents restenosis.
Angiofibroma
Tracheal stenosis
Skull base Ostemyelitis
Laryngeal carcinoma