All are true about warfarin except
Refer Katzung 11/e p595 Warfarin is an oral anticoagulant that acts by inhibiting the gamma carboxylation of glutamate residues in vitamin K dependent clotting factors It has a long half life It readily crosses the placenta Liver disease reduces the synthesis of clotting factors thus increases the effect of warfarin
It inhibits the activation of vitamin K dependent clotting factors
It's half life is 36hrs
It can cross placenta
It's dose is increased in liver disease
Respiratory system