Ideal time for doing quadruple test:-
Triple test : screening test It's a screening test for down syndrome ( trisomy 21) Done between 16 and 18 weeks of gestation It involves estimation of three hormones : ( hCG|, AFP|, UE3| ) To the triple test, if the level of a fouh marker dimeric inhibin alpha are added, the test is called as QUAD test or Quadruple test ( inhibin A |) 1st trimester 2nd trimester Screening test Nuchal tranaslucency + - hCG + PAPP-A Quad test /tirple test Diagnostic test ( karyotyping ) Chronic villi sampling Amniocentesis
8-12 weeks
11-15 weeks
15-18 weeks
18-22 weeks
NEET 2018