Gastric irritation is least with following NSA1D: (PGI June 2008)
Ans. B (Acetaminophen) "Gastric mucosal damageQ: Gastric pain, mucosal erosion/ ulceration and blood loss are produced by all MSAIDs to varying extents: relative gastric toxicity is a major consideration in the choice of MSAIDs. Paracetamol", a very weak inhibitor of COX is practically free of gastric toxicity and selective (misoprosto) administered concurrently with NSAIDsanatgonise their gastric toxicity"- KDT 6th/186Aspirin is acetylsalicylic acid KDT 6th/187
Diclofenac
Acetaminophen
Ibuprofen
Naproxen
Prostaglandins