Transient acute adrenal insufficiency is seen with which of the following drug.
Etomidate causes adrenal gland suppression. It inhibits an enzyme 11 beta hydroxylase on essential enzyme for coisol synthesis. Etomidate has the highest incidence (40%) of post operative nausea and vomiting (PONV) among the intravenous anesthetics. Propofol has antiemetic propeies thereby reducing PONV. Other potential adverse effects of etomidate: Adrenocoical suppression Myoclonus Seizure precipitation Pain on injection
Etomidate
Propofol
Thiopentone
Ketamine
Intravenous Anesthetic Agents