Chances of multiple sclerosis are maximum if
. *In multiple sclerosis genetic factors are also relevant ,the risk of familial recurrence in MS is 15%,with highest risk in first degree relatives (age adjusted risk:4-5% for siblings and 2-3 % for parents or off spring . Ref Harrison20th edition pg 2456
Mother has the disease
Father has the disease
Mother is carrier
Father is carrier
C.N.S