Congenital cause of hypercoagulable states are all except aEUR'
Lupus anticoagulant [Ref: Harrison I7/e p. 7321 Causes of Hy ercoa ulable state Congenital * Factor V Leiden (5% of the population are heterozygous for FVL). * Prothrombin mutation (G202 WA, 5'UTR). * High homocysteine levels due to MTHFR mutation0 * Sickle-cell disease (only small risk) * Antithrombin III deficiency. * Protein C deficiencyQ. * Protein S deficiency0. * Plasminogen and fibrinolysis disorders (very rare) Acquired * Antiphospholipid antibodies - Anti-cardiolipin antibodies and/or - Lupus anticoagulants * Heparin-induced thrombocytopenia * Paroxysmal nocturnal hemoglobinuria * Nephrotic syndrome * Hyperestrogenemia * Estrogen-containing hormonal contraceptives * Tobacco smoking * Hyperhomocysteinemia due to vitamin I312 and folic acid deficiency.
Protein C deficiency
Protein S deficiency
MTHFR mutation
MTHFR mutation