Hepatic enzyme undergoes phosphorylation from dephosphorvlated state. Which of the following is true
Ans. c. Always activated by c-AMP dependent protein kinaseEpinephrine and norepinephrine (in muscle during activity) or glucagon (in liver when blood glucose level is too low) increase concentration of c-AMP, which inturn activates c-AMP dependent protein kinase (protein kinase a or PICA).Allosteric Control of Phosphorylase occurs throughIn MuscleActivation: Ca2+degc-AMPdeg5'-AMP Inhibition: - ATPdegGlucose-6-phosphateIn LiverActivation: - c-AMPdegInhibition:ATPdegGlucose-6-phosphate Free glucosedeg
Affected by level of Catecholamines
Occurs in starvation rather than well fed state
Always activated by c-AMP dependent protein kinase
Always activates the enzyme