True about light microscopy in minimal change disease is
Ans. is `d' i.e., No change seen Impoant pathological features of Minimal Change disease: On light microscopy - No abnormality. On electron microscopy - Fusion of foot processes of epithelial cells Minimal change disease Minimal Change Disease is the most common cause of Nephrotic syndrome in children. Edema and Selective proteinuria are features of nephrotic syndrome. Fever may be present on account of increased susceptibility to infection. Minimal change disease prsents with insidious onset of nephrotic syndrome in children below 6 years of age. Hypeension is not a feature of nephrotic syndrome and is rare in Minimal change disease. Hematuria (a finding of nephritic syndrome) is also rare. Pathological findings include Light microscopy - No abnormality Electron microscopy - Obliteration (loss) and fusion of foot processes of epithelial cells. Immunofluorescence - No deposits of immune reactants Serum complements - Normal levels o Minimal change disease has very good prognosis with excellent response to steroids.
Loss of foot process seen
Anti GBM Abs seen
IgA deposits seen
No change seen