Which of the following agents scan cause recurrent fall in elderly patient with postural hypotension:
(Ref: Goodman & Gillman 13th ed. P 208-209)Prazosin is one of the non-selective alpha 1 antagonists used for treatment of hypertension and BPH.DOC for HTN + BPH: PrazosinDOC for BPH: Silodosin (selective a1a agonist)Side effect:# Marked Postural hypotension (orthostatic/first dose hypotension), syncope - can cause recurrent falls. Therefore, it is given at bedtime# Retrograde ejaculation
Methoxamine
Prazosin
Metformin
Acarbose
A.N.S.