Which of the following statements best explains the action of nitroglycerine on coronary vessels:
Nitrates cause redistribution of blood flow without affecting total coronary flow. Autoregulatory small vessels remain unaffected whereas large conducting vessels are dilated. Nitrates are predominantly venodilators, therefore decrease mainly preload.
It mitigates angina pectoris by increasing total coronary flow
It preferentially dilates conducting aeries without affecting resistance aerioles
It preferentially dilates autoregulatory aerioles without affecting the larger aeries
It mainly decreases the after load
CHF, Angina Pectoris and Myocardial Infarction