Which topical agent is antiproliferative, cytotoxic to melanocytes and a weak competitive inhibitor of tyrosinase?
Azelaic acid - Tyrosinase inhibitor Has anti-inflammatory propeies and antiproliferative effect on keratinocytes - used in acne Has cytotoxic action against Melanocytes - used in Hyperpigmentary disorders Tyrosinase inhibitors - used for hyperpigmented disorders like melasma Eg -1. Hydroquinone2. Azelaic acid 3. Kojic acid4. Arbutin
Kojic acid
Hydroquinone
Retinoids
Azelaic acid
Hypo Pigmentary Disorders