In which of the following condition is SHBG synthesis decreased?
Increase in androgen level is associated with decrease in SHBG synthesis. Other factors leading to decreased SHBG synthesis are: Obesity Hypothyroidism Excess glucocoicoids Also know: Factors leading to increased SHBG synthesis are: Estrogen Pregnancy Hypehyroidism Ref: Endocrine Pathophysiology, Second Edition By C. B. Niewoehner, page 285
Hypehyroidism
Increased estrogen
Increased androgen
Pregnancy