Poor wound healing in vitamin 'C' deficiency is due to all except -
Ans. is "a" Inhibition of collagen synthesisAscorbic acid (Vitamin C) is also called antiscorbutic factor. It is very heat labile, especially in basic medium. Ascorbic acid itself is an active form. Maximum amount of vitamin C is found in adrenal coex.Ascorbic acid functions as a reducing agent and scavanger of free radicals (antioxidant). Its major functions arevitamin C is essential for the conversion of procollagen to collagen, which is rich in hydroxyproline and hydroxylysine. Through collagen synthesis, it plays a role in the formation of matrix of bone, cailage, dentine and connective tissue.Vitamin C is required for post-translational modification by hydroxylation of proline and lysine residues conveing them into hydroxyproline and hydroxylysine.
Inhibition of collagen synthesis
Defective collagen synthesis
Defective post-translational modification of collagen
Defective hydroxylation