The drug effective for treatment as well as prophylaxis of angina pectoris is:
Isosorbide dinitrate Can be used sublingually at the time of attack (peak in 5-8 min) Orally for chronic prophylaxis. t 1/2 is 40 min, but sustained release formulation may afford protection for 6-10 hours. Nitrates are effective in classical as well as variant angina. Nitrates increase exercise tolerance and postpone ECG changes of ischemia.
Isosorbide dinitrate
Pentaerythritol tetranitrate
Diltiazem
Dipyridamole
CHF, Angina Pectoris and Myocardial Infarction