Which of the following statements about fibromyalgia is true:
Pathogenetic features in fibromyalgia:Disruption of normal stage IV NREM sleepLow levels of serotonin metabolites in CSFReduced levels of growth hormoneIncreased levels of neurotransmitter substance P in CSFDecreased coisol response to stress and coicotrophin-releasing hormoneAutonomic dysfunctionReduced blood flow to the thalamus, caudate nucleus, and tectum on SPECTPsychiatric disturbances(ref:Harrison's 18/e p2849-2851, 17/e p2180)
More common in males
Sleep EEG studies have shown disruption in REM sleep
Increased coisol response to stress
SPECT studies have reduced blood flow to the thalamus
All India exam