A methotrexate intolerant psoriasis patient has been prescribed an alternate disease modifying drug (DMARD) that resulted in liver dysfunction combined with skin rashes and bone marrow suppression of RBC's & platelets. The most probable drug is
Answer: b) Leflunomide* Abatacept is associated with infections due to inhibition of normal T-cell activity.* Sulfasalazine causes agranulocytosis and hepatitis along with rashes.* Leflunomide causes skin rashes and bone marrow suppression of RBC's & platelets.* Anakinra therapy may lead to neutropenia but not bone marrow suppression.
Anakinra
Leflunomide
Abatacept
Sulfasalazine
Immunomodulator