Spironolactone should not be given with
Sprinolanctone is a potassium sparing diurectic It doesn't excrete potassium - increasing potassium levels in the blood ACE IN. also increases potassium levels in the blood Hence the combination is contraindicated Ref: KD Tripathi 8th ed
Chlohiazide
Beta blockers
ACE inhibitors
Amlodipine
Cardiovascular system