All of the following are Vitamin-K deficiency features EXCEPT:
Ans. (a) Associated thrombocytopenia with prolonged bleedingRef: Harrison 19th ed. / 96e-8* Vitamin-K is a fat soluble compound. It promotes blood clotting by increasing hepatic biosynthesis of prothrombin and other coagulation factors.* The best sources are green leafy vegetables, liver, cheese, butter and egg yolk. Deficiency, usually seen only in neonates, in disorders of absorption or during antibiotic therapy is characterized by hemorrhage.* Warfarin acts by inhibiting Vitamin K, and does not causes deficiency of the same.
Associated thrombocytopenia with prolonged bleeding
Deficiency is rarely seen, except in infants
Factor X is first to be affected
Warfarin causes Vitamin K deficiency
Bleeding and Thrombotic Disorders