The distribution of keratins (K) in the basal layers is:
Basal layer has keratin types K5/K14 Keratin Heterodimer Sites K 5/14 Stratum basale - If defective- Epidermolysis Bullosa simplex K 1/10 Stratum Spinosum K 2/11 Stratum Granulosum K 3/12 Cornea - If defective - Corneal dystrophy K 4/13 Buccal mucosa K 6/16 Nails K 8/18 Liver - If defective - Liver cirrhosis
K5/K14
K1/K10
K2/K11
K6/K16
Cells of epidermis