Child presents with ling verracons plaques on the trunk with vacuolization of keratinocytes in S.Spinosum and S.Granulosum.Dignosis is?
NAEVI:- Circumscribed congenital anomaly of skin.Depending of cell/tissue of origin,naevi are classified as:-1. Epidermal- arising from keratinocytes 2. Melanocytic-arising from melanocytes.3. Connective tissue /vascular. EPIDERMAL NAEVI: 1. Veruccous epidermal naevi- present at bih as brownish plaques. As the child grows the lesions become more prominent and way.the lesions may be localised to a small area /appear in streaks affecting one half of body or both halves.Vacoulisation of keratinocytes in S.spinosum and S. granulosum seen . 2. Inflammatory linear veruccous epidermal naevi (ILVEN):-pruritic,erythematous and scaly.3. Sebaceous naevi-yellowish plaques on the scalp and face. On the scalp,usually devoid of hair.4. Epidermal naevus syndrome- Naevi with abnormalities in other organ systems (CNS,eye and skeleton)5. Becker's naevus:- males usually around adolescence. It appears as an irregular large area of pigmentation with hyperichosis over the shoulder and chest. MELANOCYTIC NAEVUS:- 1. Acquired- after infancy. Lesions progress and involutes as the person ages.2. Congenital-small,medium and large giant naevi. Large/giant naevi may be surrounded by satellite naevi.3. Naevus of ota- unilateral, bluish macule in the area supplied by the 1st and 2nd division of trigeminal nerve.4. Naevus achromicus-non progressive hypo pigmented macule.( vitiligo- progressive).5. Naevus anaemicus6. Naevus spilus.:- cafe au lait macules superimposed with multiple small darker melanocytic lesions. {Reference: IADVL textbook of dermatology, Page 174.
Incontinenta pigmenti
Delayed hypersensitivity reaction
Verrucous epidermal nevus
Linear darriers disease
miscellaneous