Carbonic anhydrase inhibitors should not be given in
Carbonic anhydrase inhibitors(CAIs)are more likely to produce acidosis in patients of COPD,CRF and DM.They are contraindicated in COPD as they may precipitate respiratory acidosis. They are sulfonamides in structure,so should not be given in hypeensitive persons.
Sulfonamide hypersensitivity
Glaucoma
High altitude sickness
Metabolic acidosis
Endocrinology