All are true for plemorphic adenoma except-
Pleomorphic adenomas arise most commonly in the parotid gland. These form majority (~80-90%) of tumors of the parotid gland. Pleomorphic adenomas are less common in the submandibular glands & sublingual glands; relatively rare in the minor glands. Pleomorphic adenomas are benign tumors derived from a mixture of ductal (epithelial) and myoepithelial cells, and therefore show both epithelial and mesenchymal differentiation (hence k/a mixed tumor) Although benign, it has the potential to turn malignant k/a carcinoma ex pleomorphic adenoma or malignant mixed tumor. The incidence of malignant transformation increases with the duration of the tumor Signs & symptoms suspicious of malignant transformation a) rapid growth b) pain c) paresthesias d) facial weakness e) skin invasion and fixation of mastoid tip.
May turn malignant
Arises from parotid
Minor salivary glands involved
None
Head and neck