In genetic deficiency of MPO the increased susceptibility to infection is due to -
Myeloperoxidase is an enzyme in Macrophages for production of hypochlorous radical from H2O2, which kills bacteria. Basic Pathology, Robbins. Page no.: 38
Defective production of Prostaglandins
Defective rolling of neutrophils
Inability to produce hydroxyl-halide radicals
Inability to produce hydrogen peroxide
General pathology