Rosiglitazone mechanism of action is ?
Ans. is 'a' i.e., Acts as PPAR gamma agonist Rosiglitazone It is oral antidiabetic drug They are selective agonists for nuclear peroxisome proliferator activator receptor gamma (PPAR gamma) expressed in the fat and muscle cells. It enhances transcription of several insulin responsive genes. Reverse insulin resistance by enhancing GLUT 4 expression and translocation.
Acts as PPAR gamma agonist
Inhibitor of alpha glucosidase
Acts as amylin analogue
Acts as dipeptidyl peptidase inhibitor