Which of the following statement is true regarding inverse agonists?
Inverse agonist activates a receptor to produce an effect in the opposite direction to that of an agonist. It has high affinity for the receptor, but intrinsic activity with a minus sign. Ref: Essentials of Medical Pharmacology By KD Tripathi, 5th Edition, Pages 35, 37
Binds to receptor and causes intended action
Binds to receptor and causes opposite action
Binds to receptor and causes no action
Binds to receptor and causes submaximal action