Which of the following statements regarding ticlopidine is TRUE?
Abciximab, eptifibatide and tirofiban inhibits GpIIb/IIIa receptors. Ticlopidine and clopidogrel inhibits ADP receptors. Aspirin inhibits TXA2 synthesis in platelets. Bleeding time is prolonged by antiplatelet drugs whereas PT is prolonged by oral anticoagulants and aPTT by heparin.
It blocks GpIIb/IIIa receptors on platelet membrane
It prevents ADP mediated platelet adenylyl cyclase inhibition
It inhibits thromboxane A2 synthesis in platelets
It does not prolong bleeding time
Hematology and CVS