Serious, adverse behavioral reactions, including hostility, aggression, and suicidal thoughts and behaviors are associated with which of the following drugs?
Levetiracetam is a pyrrolidine, and is FDA-approved for adjunctive therapy for myoclonic, focal-onset, and generalized onset tonic-clonic seizures in adults and children as young as 4 years old. Its s/e includes: Somnolence, anxiety, confusion, imbalance, double vision, dizziness, GI distress or nausea, and weight gain. Adverse behavioral reactions, including hostility, aggression,and suicidal thoughts and behaviors, independent of clinical history of psychiatric disorder are also seen.
Pregabalin
Topiramate
Levetiracetam
Lamotrigine
Epilepsy