Which of the following statements about anti-epileptics is false?
prolongation of Na+ channel inactivation and suppression of high frequency firing has been demonstrated. In addition, it may directly block voltage sensitive Na+ channels, thus stabilizing the presynaptic membrane and preventing release of excitatory neurotransmitters, mainly glutamate and aspaate. Ref KD Tripati 8thh ed.
Phenytoin and carbamazepine act by prolonging the inactivated state of Na+ channels
Carbamazepine can be used in trigeminal neuralgias
Diazepam is an anticonvulsant drug
Lamotrigine mainly acts by causing GABA mediated Cl- channel opening
Central Nervous system