CAR-T cells are used in the treatment of which of the following cancers?
CAR-T cells Chimeric antigen receptor (CAR) T cells are T-cells extracted from patient and modified in vitro to change T-cell receptor to detect specific protein on surface of malignant cells such as CD19 Currently approved for use in acute lymphoblastic leukemia and B-cell NHLs Examples of CAR-T cells are Kymria (ALL), Yescaa (DLBCL)
Acute lymphoblastic leukemia
Soft tissue sarcoma
Medulloblastoma
Small cell lung carcinoma
Irreversible cell Injury/Necrosis