Following is true regarding sulhydryl groups except?
Ans. is 'c' i.e., They are not involved in reduction of peroxides Sulfhydryl Group (or thiol group) It is an SH group of organic compounds. Sulfhydryl groups have great and varied reactivity. They oxidize easily, with the formation of disulfides and sulfenic, sulfinic, or sulfonic acids, and they readily undergo alkylation, acylation, and thiol-disulfide exchange. They form mercaptides upon reacting with the ions of heavy metals, and they form mercaptals and mercaptols upon reacting with aldehydes and ketones, respectively. Sulfhydryl groups play an impoant role in biochemical processes. The sulfhydryl groups of coenzyme A, lipoic acid, and 4'-phosphopantotheine paicipate in enzymatic reactions for the formation and transfer of acyl residues that are related to lipid and carbohydrate metabolism. The sulfhydryl groups of glutathione play an impoant role in the neutralization of foreign organic compounds and the reduction of peroxides; they are also of major impoance in the fulfillment by glutathione of its function as a coenzyme. In proteins, residues of the amino acid cysteine have sulfhydryl groups. As components of the active centers of a number of enzymes, sulfhydryl groups paicipate in the catalytic effect of the enzymes and in the binding of substrates, coenzymes, and metal ions. Drugs containing sulfhydryl groups are: captopril, zofenopril and penicillamine.
They are present in coenzyme A and lipoic acid
They are present in Captopril and penicillamine
They are not involved in reduction of peroxides
They are present in cysteine