A 21-year-old woman with moderately severe asthma on three-drug treatment has elevated liver function tests thought to be caused by one of her medications. Which drug is causing this adverse effect?
Zileuton It is a 5-LOX inhibitor, blocks LTC4/D4 as well as LTB4 synthesis. It therefore has the potential to prevent all LT induced responses including those exeed by activation of cysLT1 receptor. Durationof action of zileuton is sho side effects:. HEPATOTOXIC Ref:- kd tripathi; pg num:-229
Chromone agent
Lipoxygenase inhibitor
Leukotriene receptor antagonist
Methylxanthines
Respiratory system