All of the following are true for patients with ulcerative colitis associated with primary sclerosing cholangitis (PSC), Except
PSC associated with ulcerative colitis eventually leads to biliary cirrhosis. Investigations reveal a cholestatic pattern in LFT with an elevation of serum alkaline phosphatase & gamma-glutamyltransferase. The prevalence of cholangiocarcinoma in patients with PSC ranges from 7 to 13%. Reference: Bailey & love&;s sho practice of surgery,25th edition, page no:1127; SRB&;s manual of surgery,5th edition, page no:658.
The may develop biliary cirrhosis
May have raised alkaline phosphatase
Increased risk of hilar Cholangiocarcinoma
PSC reves after a total colectomy
G.I.T