Iron poisoning in 4 year child is treated by:
Desferrioxamine: The straight chain desferrioxamine molecule winds round ferric iron and forms a stable nontoxic complex which is excreted in the urine. It removes loosely bound iron as well as that from haemosiderin and ferritin, but not from hemoglobin or cytochrome. Uses 1. Acute iron poisoning: mostly in children. 2. Transfusion siderosis: occurs in thalassemia patients who receive repeated blood transfusion. Desferrioxamine 0.5-1 g/day i.m. helps to excrete the chronic iron overload; may also be infused i.v. concurrently with blood transfusion-2 g per unit of blood. Adverse effects -Desferrioxamine can cause histamine release -fall in BP, flushing, itching etc ESSENTIALS Of MEDICAL PHARMACOLOGY SIXTH EDITION -KD TRIPATHI Page:867,868
Stomach lavage
Desferrioxamine IV 100 mg
X-ray abdomen
Blood transfusion
Other topics and Adverse effects