Therapeutic drug monitoring is used in -
Ans. is 'd' i.e., Digoxin Therapeutic drug monitoring is particularly useful in following situations -1. Drugs with low safety margin -a) Digoxinb) Anticonvulsantsc) A ntiarryth micsd) Theophyllinee) Aminoglycoside antibioticsf) Lithiumg) Tricyclic antidepressants2. If individual variations are large - Antidepressants, Lithium3. Potentially toxic drugs used in presence of renal failure - Aminoglycoside antibiotic, vancomycin, cyclosporine4. In case of poisoning5. In case of failure of response without any apparent reason - Antimicrobials6. To check patient compliance - Psycho-pharmacological agents.o Drugs whose response is easily measurable eg. hvpoglycaemics (metformin), antihypertensive, diuretics, oral anticoagulants and general anaesthetics, monitoring of plasma cone, is of no value.
Diuretic
Metformin
Levodopa
Digoxin
Pharmacodynamics