Telmisaan lowers blood pressure by
Refer kDT 7/e p 561 Telmisaan blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland. Its action is therefore independent of the pathways for angiotensin II synthesis.
Inhibiting formation of angiotensin 1 to angiotensin
Inhibiting conversion ofrenin to angiotensin 1
Blocking AT1 receptors
Interfering with degradation of bradykinin
Cardiovascular system