Which antidiabetic drug is used both for type I& II DM -
Ans. is d i.e., Pramlinitide Pramlinide is the only approved drug, beside insulin, to be used in both type-I and type-2 DM. Pramilinitide This is a synthetic amylin analogue (Amylin is a polypeptide produced by pancreatic (3-cells which reduces glucagon secretion from a-cells and delays gastric emptying). Pramlintide attenuates postprandial hyperglycemia and exes a centrally mediate anorectic action. It is given by subcutaneous route and is used in both Type 1 and Type 2 DM.
Sulphonylureas
Metformin
Acarbose
Pramlinitide