A middle aged female is having essential blepharospasm and is planned to be treated with Botulinum toxin. Which of the following is not true?
Type C is most effective The initial treatment of choice in essential blepharospasm is Botulinum toxin type A. Among seven available form (A, B, C, D, E, F & G), only type A is used clinically and is most effective form. Botulinum toxin - Chemodenervation: * Type A is used * Block neuromuscular junctions (Cholinergic) * Onset 24-72 Hrs * Duration 3 months, hence need repeat injections * Dose: 1.25-5 unit/injection site. Usually given at 4 initial sites. * Response rate is 95-98%. * Adverse effects: Ptosis, Epiphora, Keratitis, dy eyes, diplopia
Need repeat injections
Diplopia may occur
Type C is most effective
Response rate is over 95%