Which of the following is activated by the binding of chemotactic agents to leukocyte membrane receptors?
Phospholipase C The binding of chemotactic agents to receptors on leukocyte cell membranes causes activation of phospholipase C. A hydrolysis reaction ensues resulting in the release of calcium from intracellular stores. The increased cytosolic calcium is impoant in the movement of the cells in chemotaxis.
Leukotriene B 4
Histamine
Phospholipase C
Tumor necrosis factor