Platelet aggregation is caused by?
Ans. (b). Thromboxone A2(Ref: Robbins 9th/pg 116-117)Thromboxone A2 (TXA2)It is produced by activated platelets and has prothrombotic propertiesIt is an Arachidonic acid metabolite of COX pathwayFunctions: It is a potent platelet aggregator & vasoconstrictorIts effect is neutralized by prostacyclin (PGI2)
Nitrous oxide
Thromboxone A2
Aspirin
PGE2
Bleeding Disorders