Perampanel is
Perampanel is recently approved selective non-competitive antagonist of AMPA receptorwhich is used as add on therapy for paial seizure. Adverse effect of this drug is somnolence, weight gain Felbamate is NMDA inhibitor Barbiturates are GABA mimetic Ethosuximide , valproate inhibit the calcium channels.
NMDA antagonist
AMPA antagonist
GABA mimetic
Calcium channel inhibition
Epilepsy