All of the following anti-microbials show Concentration dependent Killing except
* Time dependent killing(TDK) : Here, the killing activity depends upon the length of time, plasma concentration is above MIC. It is shown by:* Beta Lactams.* Vancomycin* Concentration dependent killing(CDK) : Here, killing activity depends upon the ratio of plasma concentration to MIC.It is shown by:* Aminoglycosides.* Flouroquinolone* MetronidazoleTDK and CDK mainly apply to cidal drugs.So, Penicillin G is beta lactam and follows TDK.
Amikacin
Metronidazole
Penicillin G
Fluoroquinolones
Cell Wall Synthesis Inhibitors