Which of the following is not a minor diagnositic criteria for multiple myeloma?
In the NCCN guidelines, active multiple myeloma is no longer diagnosed using the CRAB criteria (hyperCalcemia, Renal failure, Anemia, Bone lesions) for end-organ damage. The current diagnostic criteria are as follows : Bone marrow clonal plasma cells >=10% or bony or extramedullary plasmacytoma (confirmed by biopsy)
Lytic bone lesions
Plasmacytosis greater than 20%
Plasmacytoma on biopsy
Monoclonal globuline spike on serum electrophoresis of> 2.5 g/dl for IgG, > 1.5 g/dl for IgA
Haematology