A 28yr old female known case of asthma, on inhalational salbutamol, budesonide, and salmeterol. She complains of dyspnea. PEF is mildly improved. You have added zafirlukast to her prescription. What is the mechanism of action of zafirlukast?
Montelukast and zafirlukast act by inhibiting the actions of slow reactive species (SRS-LTC4, D4)- Cysteine leukotriene receptor inhibitorsZileuton inhibits the formation of leukotrienes., Ref: Katzung 13th ed.Pg 350.
Inhibition of actions of LTB4
Inhibition of actions of LTC4, D4
Inhibition of formation of LTC4, D4
Inhibition of release of Leukotrines from mast cells
Respiratory system