Use of tiotropium is contra–indicated in:
SPIRIVA HANDIHALER (tiotropium bromide inhalation powder) is indicated for the long-term,
once-daily, maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD), 
including chronic bronchitis and emphysema. SPIRIVA HANDIHALER is indicated to reduce exacerbations in COPD patients
Bronchial asthma
Hypertension
Urinary retention
Peptic ulcer disease