Prophylaxis of is essential to prevent which vitamin deficiency in patients taking isoniazid?
Ans. is 'd' i.e., B6 * Isoniazid reacts with pyridoxal to form a hydrazone, and thus inhibits gneration of pyridoxal phosphate.* Isoniazid also combines with pyridoxal phosphate to interfere with its coenzyme function. Due to formation of hydrazones, the renal excretion of pyridoxine compounds is increased.* Thus, isoniazid therapy produces a pyridoxine deficiency state.
B1
B2
B3
B6
Nutrition