True statement about cyclooxygenase -2 is:
COX-1 is a house-keeping enzyme that is responsible for the generation of gastroprotective PGs. COX-2 is an inducible enzyme whose production is markedly increased at inflammatory sites. Indomethacin is a nonselective inhibitor of both isoforms of COX.
It is not inhibited by indomethacin
It is inducible
It generates cytoprotective prostaglandins in gastric mucosa
It is found only in fetal tissues
NSAIDs, Gout and Rheumatoid Ahritis