False about quinidine in is
Refer kDT 6/e p 511,512 Quinidine has following propeies; Class 1a and 3 antiarrhythmic propeies Increase the effective refractory period Anti vagal action causes tachycardia. This tachycardia is paradoxical, because quinidine is a cardiac depressant and does not expected to increase the hea rate some Alpha blocking propey is and its use can cause hypotension and is not used for antihypeensive agent. At higher doses, Cinchonism occurs, characterized by ringing in ear, veigo, headache and visual disturbances ,mental changes and delirium Antimalarial action is Poorer than quinine. ECG changes:increase PR and QT interval, and broadens QRS complex, and change the shape of T wave
It increases effective refractory period
Used in hypeension
Causes paradoxical tachycardia
Cinchonism is seen
General anatomy