Isoprostanes are formed from archidonic acid by -
isoprostanes are prostaglandin stereoisomers Cycloxygenase pathway Thrombaxne and prostaglandin are formed Lipoxyenase pathway leukotienes are formed these are formed by Non-enzymatic free radical peroxidation of AA these have potent vasoconstrictor activity and modulate WBC and platelet adhesion ref robbins 9th ed page 84
Cycloxygenase
Lipoxygenase
Epoxide hydrolase
Non-enzymatic free radical peroxidation
General pathology