Smudge cells in the peripheral smear are characteristic of:
In CLL the peripharal blood contains increased number of small round lymphocytes with scant cytoplasm. These cells are fragile and are frequently disrupted in the process of making smears,producing so called smudge cells.(ref Robbins 7th/673)
Chronic myelogenous leukemia
Chronic lymphocytic leukemia
Acute myelogenous leukemia
Acute lymhoblastic leukemia
Haematology