All are intermediate filaments except
Intermediate filaments Impa tensile strength to tolerate mechanical stress Tissue-specific patterns of expression Useful for assigning cell of origin for poorly differentiated tumours Intermediate filaments Tissue Lamin A, B and C Nuclear lamina of cells Vimentin Mesenchymal cells (fibroblasts, endothelium) Desmin Muscle cells, forming scaffold on which actin & myosin contract Neurofilaments Axons of neurons, impaing strength & rigidity Glial fibrillary acidic proteins Glial cell around neurons Cytokeratins Acidic (type I) & neutral/basic (type II); used as cell markers
Lamin
Cadherin
Vimentin
Desmin
General pathology