Skin lesion in meningococcal meningitidis is due to
The endotoxin lipopolysaccharide of Meningococci is released by autolysis.- vascular endothelium is paicularly sensitive to the endotoxin. All major inflammatory cascade systems, as well as cytokines and nitric oxide, are triggered and unregulated. Reference: Textbook of Microbiology; Anathanarayan and panicker's; 10th edition; Page no: 232
Exotoxin
Endotoxin
Allergic reaction
Direct vascular Damage
Bacteriology