Indocyanine Green Angiography (ICG Angiography) is most useful in detecting:
A i.e. Occult CNV Diagnossi & Therapy 6th / 25 Yanoff 3rd / 542, 543] Major uses of ICG (Indocyanine Green) Angiography - Detect Occult Choroidal Neovascular membranes (occult CNV) or their recurrence post treatment Q. 'The greatest utility of ICG angiography is in the identification and delineation of poorly defined or occult CNV'. - Suspected Retinal Pigment Epethelium Detachments (RPE detachment) Q Angiography for Choroidol and Retinal Conditions Criteria Fluorescin Angiography (FA) Indocyanine Green Angiography (ICG Angiography) Primary Use In the study of Retinal vasculature In the study of Choroidal Vasculature Principle Fluorescin molecule is relatively small. ICG is a larger molecule than fluorescin, and Because of this fluorescin freely crosses the is typically protein bound. Because of this wall of small choroidal vessels and settles in ICG molecules are retained in the choroidal the retinal vessels and some large choroidal circulation and make ICG ideal for detecting vessels. This makes FA primarily a study of the retinal vasculature, and evaluating choroidal abnormalities Limitations Fluorescin Angiography gives limited ICG Angiography gives significant & Strength information on poorly defined lesions in information on even poorly defined lesions choroidal circulation and Retinal Pigment in choroidal circulation and Retinal Pigment Epethelium Epethelium - Because some Fluorescin molecules settle - 'The greatest utility of ICG angiography is in only in the large choroidal vessels, poorly the identification and delineation of poorly defined lesions like occult CNV are not adequately evaluated by ICG angiography defined or occult CNV'. - Retinal pigment Epethelium (RPE) - Retinal Pigment Epethelium (RPE) detachments are less readily observed on detachments are observed more readily on ICG FA angiography.
Occult Choroidal Neovascularization (Occult CNV)
Classic choroidal neovascularization (Calssic CNV)
Angioid streaks with choroidal Neovascularization (CNV)
Polypoidal choroidal vasculopathy