Which of the following is not directly controlled by ACTH?
THe secretion of the adrenal medullary hormones(epinephrine, norepinephrine and dopamine) is not controlled directly by ACTH. ACTH controls mainly secretion of adrenal coical hormones: Glucoicoids (coisol, coicosterone) and sex steroids (testosterone, DHEA, androstenedione ). Note: The major regulators of aldosterone are angiotensim II and potassium. However, ACTH can also stimulate aldosterone prooduction. Hormones secreted Regulated by Zona glomerulosa Mineralocoicoids (aldosterone) Angiotesin II, K+ Zona fasiculata Glucocoticoids (coisol, coicosterone) ACTH Zona Reticularis Sex steroids (DHEA, DHEA-S) ACTH Adrenal medulla Catecholamines(Epinephrine, norepinephrine) DIffuse sympathetic discharge(stress) REf: Guyton and Hall 13th edition Pgno: 965,966
Glucocoicoids
Androstenedione
Dehydroepiandrosterone
Epinephrine
Endocrinology