Laboratory monitoring of which of the following is desirable with low molecular weight heparin therapy: March 2012
Ans: D i.e. anti-factor Xa activity Laboratory monitoring of anticoagulant LMW heparin selectively inhibit factor Xa with little effect on Ha. So LMW heparins have smaller effect on aPTT and whole blood clotting time. Since aPTT/clotting times are not prolonged, laboratory monitoring is not needed LMWH therapy is monitored by the anti-factor Xa assay, measuring anti-factor Xa activity.
aPTT
CT
PT
Anti-factor Xa activity