Best specimen for rabies diagnosis in living person:
o Biopsy of hair follicle of base of neck is more sensitive and considered as the best sample for direct florescent antibody (DFA) test done for antemoem diagnosis of Rabies. o Corneal smears, biopsy from hair follicle from the nape of the neck, and saliva are the used specimens for antemoem diagnosis of rabies. o Corneal impression smear is only 30% sensitive, mainly it is positive in late stage. o The brain biopsy of the dead animal is the specimen of choice for postmoem diagnosis of rabies.
Corneal smear
CSF
Biopsy of hair follicle of neck
Brain biopsy
Virology Pa-2 (RNA Virus Pa-1,2 & Miscellaneous Viruses)