MOA of Teduglutide in sho bowel syndrome?
Ans. A. GLP-2 inhibitorGlucagon-like peptide-2 (GLP-2) - Impoant intestinotrophic growth factor & mediator of intestinal adaptation.FDA approved teduglutide (Gattex--NPS) to treat sho bowel syndrome in adult patients requiring additional nutrition from I.V. parenteral nutrition.Effectively improves fluid absorption.
GLP-2 inhibitor
HT1a inhibitor
GLP-1 analogs
C-peptide analogs