Which of the following drugs should not be administered concomitantly with warfarin as it decreases the effect of oral anticoagulants?
Estrogen increases the synthesis of various clotting factors and produce a hypercoagulable state. Thus OCP containing estrogen decrease the effectiveness of warfarin and other oral anticoagulants.
Broad spectrum antibiotic
Cimetidine
Aspirin
Oral contraceptive
Hematology