Conversion of Pyruvate to Acetyl CoA does not require
Pyruvate is conveed to acetyl CoA by oxidative decarboxylation catalysed by a multienzyme complex, known as pyruvate dehydrogenase complex (PDH) The enzyme PDH requires five cofactors (coenzymes), namely--TPP(thiamine pyrophosphate), lipoamide, FAD, coenzyme A and NAD+ ref Satyanarayana biochemistry 4th ed page 252
Thiamine
TPP
Pyridoxine
FAD
vitamins