Calcium blocking agents of use in the treatment of hypeension include
Nifedipine The overriding action of Nifedipine is aeriolar dilation, t.p.r. decreases and BP falls.Doesn&;t depress SA node or A-V conduction.Reflex sympathetic stimulation of hea predominates leading to tachycardia, increased contractility and C.O., coronary flow is increased.Its use is associated with higher moality among post-MI patients.Relaxant effect on the bladder, Nifedipine can increase urine voiding difficulty in elderly malesContraindicationsSide effectsHea failure 2nd or 3rd-degree hea blockTachycardia, flushingGI disturbancesHyperkalemia, edema, headache(Refer: Harrison's Principles of Internal Medicine, 18th edition, pg no: 2054-2057)
Prazosin
Lidoflazine
Captopril
Nifedipine
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