Alpo&;s syndrome is due to defective-
Out of various hereditary nephritis, Alpo's syndrome is relatively more common and has been extensively studied. This is an X-linked dominant disorder having a mutation in a-5 chain of type IV collagen located on X-chromosome. Ref: Harsh Mohans textbook of pathology 6th edition page 678
Collagen
Elastin
Fibrillin
Proteoglycan
Urinary tract