The HLA class3 region genes are impoant element in
Ref Robbins 9/e p215 Anantha Narayana 6/e p108 Class III molecules include several secreted proteins with immune functions: components of the complement system (such as C2, C4, and B factor), cytokines (such as TNF-a, LTA, and LTB), and heat shock proteins.
Translate rejection phenomenon
Governing susceptibility to autoimmune disease
Immune surveillance
Antigen presentation and elimination
General anatomy