True statement regarding zero order kinetics is:-
Zero Order Kinetics: Half life is less at low concentrations and more at high concentrations. Rate of elimination is independent of plasma concentration. Clearance is more at low concentrations and less at high concentrations. Very few drugs follow pure zero order kinetics e.g. alcohol
Half life is constant
Rate of elimination is dependent on plasma drug concentration
Clearance decreases with increase in plasma concentration
Applies to majority of the drugs
Pharmacokinetics