Chediak higashi syndrome, defect is-
Chediak higashi syndrome -Defective phagolysosomal fusion leading to decrease in melanocytes Severe Combined Immunodeficiency- Deficiency of Purine Nucleoside Phosphorylase Chronic Mucocutaneous Candidiasis- T cell disorder leading to recurrent candidiasis X linked Hyper IgM Syndrome- Deficiency of CD40 Ligand on activated T cell
Fusion of lysosome
T-cells
B-cells
Complement
Immunology Pa 3 (Graft, Autoimmunity, Immunodeficiency Disorders)