Which one of the following statement is true about Dipivefrine?
Dipivefrine penetrates the cornea and is then hydrolysed to epinephrine by esterase enzymes. It increases outflow of the aqueous humour and also reduces its formation (mediated by its action on a1 and a2 receptors), thus reducing pressure inside the eye. Ref Davidson 23rd edition pg 457
It is not a prodrug
It causes vasodilation
It penetrates the cornea and gets conveed to epinephrine
It increases intraocular pressure
Miscellaneous