All of the following are true about Drug induced Lupus; Except:
Answer is C (Renal involvement): Renal involvement is rare in Drug induced Lupus Drug induced lupus is associated with Antihistone antibodies, rare anti ds DNA and serositis. Drug induced Lupus: Features Syndrome of Positive ANA with symptoms such as fever, malaise, ahritis, intense ahralgia/myalgia, serositis and / or rash (ANA usually appears before symptoms) Predominant in Caucasians Less female predilection than SLE Commonly associated with Anti-Histone Rarely associated with Anti- ds DNA Rarely involves kidney or brain Syndrome usually appears during therapy with ceain medications and biologic agents Syndrome usually resolves over several weeks after discontinuation of the offending medication.
Anti histone antibody
Rare anti ds DNA
Renal involvement
Serositis