True statements about neostigmine are
(Ref. KDT6/e p101-102; Lee 12/ep217) Neostigmine is a reversible cholinesterase inhibitor.It is a quaernary ammonium compound. (lipid insolube agent), so it does not cross blood-brain-barrie. It is paly hydrolyzed by serum cholinesterase and paly excreted unchanged by the kidneys. It possesses some agonistic action on NM receptors.
It is a quaternary ammonium compounds
It is metabolized by the liver
It can cross the blood brain barrier
Prominent effect on cardiac muscle
Autonomic nervous system