Which of the following is mechanism of action of dapsone?
Dapsone is analogue of PABA Competively inhibits dihyropteroate synthase - decreases folic acid synthesis. It can cause mild hemolysis, anemia and psychosis. Uses: Leprosy Malaria Prophylaxis of pneumocystitis Dermatitis herpetiformis
Inhibit the cell wall synthesis
Inhibit the sterol of cell wall
Inhibit the protein synthesis
Compete with PABA in folic acid synthesis
Mycobacterial Diseases (TB, Leprosy and MAC)