All of the following statements are false regarding sarcoidosis, except:
Sarcoidosis The lungs are involved is seen in 90% cases. Clinical manifestations include lymph node enlargement, eye involvement (sicca syndrome , iritis, or iridocyclitis), skin lesions (e.g., erythema nodosum), and visceral (liver, skin, marrow) involvement. Lymph nodes are involved in almost all cases, paicularly the hilar and mediastinal nodes. Intra-alveolar and interstitial accumulation of CD4+ T cells, resulting in CD4/CD8 T-cell ratios ranging from 5:1 to 15:1. Schaumann bodies and asteroid bodies are seen on microscopic examination. These are not pathognomonic of sarcoidosis because these may be seen in other granulomatous diseases (e.g., tuberculosis).
Schaumann bodies and asteroid bodies are not seen
BAL (broncho-alveolar lavage) fluid shows CD8/CD4 T cell ratio of 4:1
Hilar and mediastinal lymph nodes are spared
Can be associated with unilateral or bilateral iritis or iridocyclitis
Sarcoidosis