Leber's optic neuropathy-
Leber's hereditary optic neuropathy is a mitochondrial disorder. Since mitochondrial DNA is exclusively derived from mothers, males do not transmit the disease.
The optic disc becomes pale and atrophic in late atrophic phase (not early).
Typically presents in the fourth decade of life
Males do not transmit the disease
Is inherited in autosomal X-link fashion
The optic disc is pale early in the disease