The activity of pyruvate carboxylase is dependent upon the positive allosteric effector
Pyruvate carboxylase is an allosteric enzyme. Acetyl CoA is an activator of pyruvate carboxylase so the generation of oxaloacetate is ored when acetyl CoA level is sufficiently high.Ref: DM Vasudevan, 7th edition, page no: 120
Succinate
AMP
Isocitrate
Acetyl Co A
Metabolism of carbohydrate