Itai - Itai disease is caused by:
Cadmium poisoning causes itai-itaidisease which is also known as ouch ouch disease due to cadmium contaminated water. Cadmium poisoning also causes other signs and symptoms like yellowing of teeth(Cadmium ring formation) and chronic renal failure.
Mecury toxicity
Cadmium toxicity
Lead toxicity
Arsenic toxicity
JIPMER 2018