Bioavailability ?
Ans. is 'c' i.e., Area of oral/ area of IV x 100 Bioavailability Refers to the rate and extent of absorption of drug from a dosage form as determined by its concentration-time curvein blood or by its excretion in urine. It is the measure of fraction (F) of drug, which reaches the systemic circulation in unchanged form. Bioavailability of a drug given by i.v.route is 100%. So the bioavailability of drug dosage form is determined by comparing it with the i.v.route.
Area of oral/ area of IV
Area of IV/ area of oral
Area of oral/ area of IV x 100
Area of IV/ area of oral x 100