Characteristic feature of apoptosis -
Ans. is 'a' i.e., Cell membrane intact o No option is exactly correct in this question, as chromatin condensation is the most characteristic feature of apoptosis. o But, we have to choose one option anyways. o Amongst the given options two features are seen in apoptosis : ? Option a --> Cell membrane intact Option b ----> Cytoplasmic eosinophilia o Cytoplasmic eosinophilia is not characteristic feature of apoptosis; cytoplasmic eosinophilia is also seen in necrosis. o On the other hand Intact cell membrane is a striking feature of apoptosis and it differentiates apoptosis from necrosis (in which cell membrane is damaged) o Most characteristic feature of apoptosis o Earliest change of apoptosis o End stage of apoptosis o Most striking feature of apoptosis -> Chromatin condensation (Pyknosis) - Cell shrinkage ---> Formation of cytoplasmic blebs & apoptotic bodies. - Absence of inflammation.
Cell membrane intact
Cytoplasmic eosinophilia
Nuclear moulding
Cell swelling