About Apoptosis ,true statement is
Ref Robbins 8/e p25; 7/e p26;9/e p823 Councilman body, also known as Councilman hyaline body or apoptotic body, is an acidophilic (eosinophilic / pink-staining on H&E) globule of cells that represents a dying hepatocyte often surrounded by normal parenchyma. ... It represents a hepatocyte that is undergoing necrosis/apoptosis In H&E-stained tissue sections, the nuclei of apoptotic cells show various stages of chromatin condensation and aggregation and, ultimately, karyorrhexis (Fig. 1-21); at the molecular level this is reflected in fragmentation of DNA into nucleosome-sized pieces. The cells rapidly shrink, form cytoplasmic buds, and fragment into apoptotic bodies composed of membrane-bound vesicles of cytosol and organelles (Fig. 1-6). Because these fragments are quickly extruded and phagocytosed without eliciting an inflammatory response, even substantial apoptosis may be histologically undetectable
Injury due to hypoxia
Inflammatory reaction is present
Council man bodies are associated with Apoptosis
Cell membrane is damaged
General anatomy