True about alpha-1 antitrypsin deficiency,is :
Alpha-1 antitrypsin deficiency is an autosomal recessive disease marked by abnormally low serum levels of alpha1 AT enzyme resulting in panacinar emphysema.(ref Robbins 9/e p675-676)
Autosomal dominant
Pulmonary emphysema
Disease resistant hepatic cells
Hepatic cells are orcein stain positive
Respiratory system