Characteristic of Barrett's esophagus is?
Ans. is 'b' i.e. Columnar metaplasia * Barrett's esophagus is a metaplasia in which normal squamous epithelium of lower part of esophagus is replaced by columnar epithelium due to prolonged esophageal reflux.* Most common type of metaplasia in Barrett's esophagus is intestinal metaplasia which is characterized by presence of intestinal goblet cells in the metaplastic columnar epithelium.* Barrett's esophagus is a pre-malignant condition. It is the single most important risk factor for adenocarcinoma of esophagus.
Increased risk of SCC
Columnar Metaplasia
Most commonly in middle one third of esophagus
Gastric metaplasia is most common
G.I.T.