Following is Hib conjugate vaccine -
Ans. is 'd > c' i.e., PRP with carrier > Capsular polysaccheride with carrier o Conjugated Hib vaccine include PRP (polyribosyl ribitol phasphate) covalently linked to carrier protein. PRP is the Capsular polysaccaride of H influenzae type B (Hib).o Currently three types of Hib (H influenzae type B) vaccines are available. These vary in -a) Protein carrier usedb) The molecular size of saccharidec) Mehtod of conjugation of protein to saccharide o These vaccines are -i) HbOC (mutant diphtheria toxin as the carrier protein)ii) PRP-T (Tetanus toxoid as the carrier protein)iii) PRP-OMP (major OMP of N meningitidis serogroup B as carrier)
Capsular polysaccharide
Cell wall polysaccheride
Capsular polysaccheride with carrier
PRP with carrier
Influenza