Epstein Barr virus causes autoimmunity by -
Polyclonal B cell activation: in this hypothesis, while an antigen generally activates only its corresponding B cell, ceain stimuli non specifically turn on multiple B cell clones. A Such stimuli include virus ( EB virus), enzymes (trypsin), bacteria ( mycoplasma) etc It is type 4 human herpes virus Reference : Anathanarayan & paniker's 9th edition, pg no: 179 <\p>
Molecular Mimicry
Release of Sequestrated Antigen
Inappropriate Expression of MHC Class II Molecules
Polyclonal B cell Activation
Immunology