Incomplete closure of ectodermal cleft is know to cause
Inderbir Singh&;s Human embryology Tenth edition Pg 364 Failure of the choroidal fissure to obliterate completely may lead to deficiencies( coloboma)of various layers of eyeball including iris ciliary body and choroid
Retinal detachment
Iridodonesis
Retinoblastoma
Coloboma of iris and retina
General anatomy