Autosplenectomy is seen in:
- In sickle cell anemia initially, congestive splenomegaly is seen. - Later, sickled RBC causes aerial occlusion - ischemic damage to spleen - resulting in Fibrosis of spleen / autosplenectomy.
Hereditary spherocytosis
Sickle cell disease
Thalassaemia
Autoimmune anemia
Hemoglobinopathies: Sickle cell anemia