Aspirin should be used with caution in the following groups of patients because of which of the following reason:
Aspirin- Urate excretion: Aspirin in high dose reduces renal tubular excretion of urate- dose more than 5 grams per day- that is more than the antiinflammatory dose ESSENTIALS OF MEDICAL PHARMACOLOGY;7TH EDITION; KD TRIPATHI; PAGE NO 195
In diabetics because it can cause hyperglycemia
In children with viral disease, because of the risk of acute renal failure
In gout, because it can increase serum uric acid
In pregnancy, because of high risk of teratogenicity
Autacoids