Arrange the following drugs according to their half life in increasing order 1. Amiodarone 2. Adenosine 3. Esmolol 4. Omeprazole
Amiodarone is longest acting anti-arhythmic drug. Its half life is more than 3 weeks. Adenosine is shoest acting anti-arrhythmic drug having half life less than 10 seconds. Esmolol is an ultra sho acting beta blocker. It is metabolized by pseudocholinesterase and thus has half life less than 5 minutes. Omeprazole has half life of 1-2 hours but works for 24 hours due to irreversible inhibition of proton pump. Thus, the sequence is Adenosine < Esmolol < Omeprazole < Amiodarone
1-2-4-3
2-3-1-4
4-3-1-2
2-3-4-1
Hypeension, Arrhythmias, Dyslipidemia