Investigation of choice in hirschsprug's disease is ?
Answer 'c' i.e. Rectal biopsy Definitive diagnosis is made by rectal biopsy. The histopathology of Hirschprung's disease is the absence of ganglion cells in the nerve plexus, presence of hyperophied nerve bundles and increased acetylcholinesterase-positive nerve fibres.
Rectal manometry
Rectal examination
Rectal biopsy
Ba enema