Which one of the following is not a feature of liver histology in Non cirrhotic poal fibrosis (NCPF) ?
Ans. is 'd' i.e., Bridging fibrosisFibrosis bridging one poal tract to another (bridging fibrosis) is not seen.Pathology : o Non cirrhotic poal fibrosis is primarily a vascular disorder of the liver characterized by fibrous intimal thichening of the poal vein or its branches in patients with non cirrhotic protal hypeension.Vascular changesHallmark of the disease is thrombosis/sclerosis of the poal vein branches.The poal vein is dilated with sclerosis of the walls and in autopsy thrombin in medium or small poal vein branches with accompanying areas of ischaemic necrosis have been repoed.Aberrant Intrahepatic vessels may be present in the peripoal area, which correspond to dilated terminal poal vein branches or venules. These are often termed as "megasinusuoids" or peripoal angiomatosis. FibrosisVascular changes are accompanied by poal and peripoal fibrosis of varying extent.
Fibrosis in and around the poal tracts
Thrombosis of the medium and small poal vein branches
Non specific inflammatory cell infiltrates in the poal tracts
Bridging fibrosis