Cholangiocarcinoma histologically resembles
It resembles schirrhous type because of fibrosis and desmoplastic reactions Based on macroscopic growth pattern cholangiocarcinoma divided into Sclerosing MC type Causes intense desmoplastic reaction Seen as diffuse thickening of the ducts without defined mass. This form is most diffucult to treat. Nodular Result in mass lesion Usually intrahepatic. Papillary Rare Low grade adenocarcinoma. Represented by polypoid mass filling the lumen of bile duct Minimal invasion and no desmoplastic reaction. More common in distal CBD. Associated with ourable outcome Ref: Sabiston 20th edition Pgno :1514-1518
Squamous cell type
Colloid cell type
Schirrhous type
Columnar type
G.I.T