Intractable secondary glaucoma is seen in:
Ans. (a) Diffuse iris melanomaRef: Surgical Pathology of Head & Neck p. 1935Intractable secondary glaucoma may also occur in cases of blunt trauma due to anteriorly dislocated lens setting caught in the pupil.Iris melanoma(malignant neo plasms that arise from neuroectodermal melanocytes with in the Iris)Circumscribed/nodular iris melanoma* Present as pigmented spot on the iris* These tumors are usually localized, well circumscribed and nodular* These tumors usually tend to involve only a limited segment of the angle circumference and hence glaucoma is less common and usually treatableDiffuse iris melanoma* Present as a unilateral dark iris (hyperchromic heterochromia) Q* These tumors show a flat and diffuse infiltration pattern of growth* The infiltration invades the intertrabecular spaces and plugs the drainage mechanism, resulting in an intractable secondary glaucoma
Diffuse iris melanoma
Nodular iris melanoma
Melanocytic deposits in anterior part of iris
Melanocyte proliferation in posterior uveal tissue
Uveal Tract