The HLA class-III region genes are impoant elements in
HLA class III region contains genes that encode several components of the complement system (i.e. C2, C4a, C4b, Bf), they are responsible for the levels of components of the complement system. In addition to components of the complement system, MHC III genes code inflammatory cytokines, tumour necrosis factor a and 0 (TNF a and P), two heat shock proteins (HSP) Ref : Ananthanarayana textbook of Microbiology 9th edition Pgno : 140
Transplant rejection phenomenon
Complement system
Immune surveillance
Antigen presentation and elimination.
Immunology