Drug implicated for prolongation of QT interval in a premature baby is -
Ans. is 'c' i.e., Cisapride Cisapride inhibits the delayed rectifying IC- channels in hea and can cause prolongation of QT interval. o Drugs inhibiting CYP3A4 enzyme can precipitate Torsaes DePointes, Caused by cisapride eg; clarithromycin, erythromycin, cyclosporine, fluconazole, itraconazole, ketoconazole, Nefazodone, Ritonavir, Fluvoxamine.
Domperidone
Metoclopramide
Cisapride
Omeprazole