Aromatase enzyme
Aromatase enzyme conves androgens to estrogens.5a-Reductase conves testosterone to dihydrotestosteroneAromatase inhibitors block the function of the aromatase enzyme that conves androgens to estrogens. Aromatase inhibitors, including letrozole, anastrozole, and exemestane, are highly effective for both adjuvant and metastatic treatment of breast cancer in postmenopausal subjects,5a-Reductase inhibitors like finasteride, dutasteride are used in BPHG&G 12e 1953
Conves estrogen to androgen
Conves androgen to estrogen
Helps in maintaining normal placental blood flow
Conves testosterone to dihydrotestosterone
Endocrinology