Malignancy associated hypercalcemia is due to?
Ans. is 'b' i.e., Parathyroid related peptide * Hypercalcemia is the most common paraneoplastic syndrome. Most commonly it is caused by parathyroid hormone-related peptide (PTHRP), followed by TNF-a, IL-1, and TGF. Lymphomas cause hypercalcemia due to secretion of 1, 25 dihydroxy vitamin D (Calcitriol).
Tumor lysis syndrome
Parathyroid related peptide
IL-7
IGF-b