The Lab investigation of a patient shows |T4, & |TSH Which of the following is the most likely diagnosis:
|T4, & |TSH - suggests primary hypothyroidism Chronic thyroiditis or Hashimoto's disease is a common thyroid gland disorder. It can occur at any age, but is most often seen in middle-aged women. It is caused by a reaction of the immune system against the thyroid gland. The disease begins slowly. It may take months or even years for the condition to be detected. Chronic thyroiditis is most common in women and people with a family history of thyroid disease. Laboratory tests to determine thyroid function include: 1. Free T4 test (low) 2. Serum TSH (high) 3. T3 (low or normal) Thyroid autoantibodies: Antithyroid peroxidase pothalamic failure are causes of secondary hypothyroidism with low TSH and T4 Ref: Harrison's 16th Edition, Page 2109 (table)
Grave's disease
Hashimoto's disease
Pituitary failure
Hypothalamic failure