True statement regarding Hirschsprung's disease?
Ans. is 'c' i.e., Manometry excludes the diagnosis o Anorectal manometry is a useful screening procedure for the diagnosis of Hirschsprung's disease. A normal response in course of manometric evaluation precludes diagnosis of Hirschsprung's disease. o However the confirmation of diagnosis in case of Hirschsprung's disease is done by rectal biopsy.
Giant ganglia are present
Mucosa is involved and show foldings
Manometry excludes the disease
Rectal biopsy is contraindicated in infants