Gene instability associated with malignancy is seen in -
Ans. is 'b' i.e., Ataxia telangiectasiaSyndromes of defective DNA repair have such a high level of chromosomal instability that they are known as chromosome-breakage syndromes or chromosomal instability syndromes.
Klippel fiel syndrome
Ataxia telangiectasia
Marfan'g syndrome
EDS