Self-inﬂicted bites are seen in:
Lesch-Nyhan syndrome:

Inherited X-linked recessive disorder, affects only males.
Enzyme defect – hypoxanthine guanine phosphoribosyl transferase (HGPRT)
Characterized by excess production of uric acid leading to GOUT.
Self-mutilation – bite their fingers and lips.
Neurological abnormalities like mental – retardation, aggressive behavior, learning disability occur.
Neurological symptoms may be due to dependence of brain on the salvage pathway.
Nephrolithiasis – leads to renal failure.
Lesch-Nyhan syndrome
Friese Maria syndrome
Cockayne syndrome
Brodie syndrome