Splenic macrophages in Gaucher's disease differ from those in ceroid histiocytosis by staining
In Gaucher's disease there is an accumulation of Gaucher cells that Contain glucocerebroside which is a lipid (glycolipid)
In ceroid histocytosis, there is an accumulation of lipofuscin (ceroid), a yellow-brown cytoplasmic pigment, in the histiocytes.
Lipids
Phospholipids
Acid Fast Stain
Iron