Baclofen is used in:-
GABAB (It is a G protein coupled receptor unlike GABAA, which is an ionotropic receptor) agonists like baclofen increase K+ conductance and can inhibit monosynaptic as well as polysynaptic reflexes. Baclofen is used to relieve spasticity in multiple sclerosis and spinal injuries. It is not useful in cerebral palsy.
Parkinsonism
Epilepsy
Spasticity
Stroke
Anaesthesia