Out of the four layers, which cells of are the most active for protein synthesis:
The spinous (prickle) cells resemble a cocklebur or sticker that has each spine ending at a desmosome. Of the four layers, the spinous cells are the most active in protein synthesis. These cells synthesize additional proteins that differ from those made in the basal cells.
Spinous cell.
Basal cell.
Granular cell.
Corneum cell.