Multifactorial causation of disease theory was proposed by
Traits and conditions that are caused by more than one gene occurring together are multifactorial, and diseases that are caused by more than one factor interacting (for example, heredity and diet in diabetes) are multifactorial. Ref: 25th edition, Park's Textbook of Preventive and Social Medicine, Page no. 40
Louis Pasteur
Pettenkofer
Robe Koch
Aristotle
Concept of health and disease