Many drugs are used as rescue therapy for preventing the adverse effects of anticancer drugs. Folinic acid is used in:-
DHF | DHF reductase<-------- inhibited by METHOTREXATE THF/FOLINILACID/LEVCOVORIN Thereforeto treat MTX toxicity FOLINIC ACID/LEVCOVORIN is used. B: Cisplatin Vomiting d/tcisplatin :ONDANSETRON Nephrotoxicity :AMIFOSTINE C: cardiotoxicity d/t doxorubicin : DEXRAZOXANE D: hemorrhagic cystitis d/t cyclophosphamide : MESNA
Methotrexate toxicity
Cisplatin toxicity
Doxorubicin toxicity
Cyclophosphamide toxicity
FMGE 2017