Trident hand is seen in _______
Trident hand is seen in achondroplsia; sho with stubby fingers, with a seperation between the middle and ring fingers. Achondroplasia: Autosomal-dominant chondroplasia; most common condition chracterized by dispropoionate sho stature. Caused by mutations in the gene coding for fibroblast growth factor receptor type 3 (FGFR3) Clinical features: Sho stature, extreme joint laxity, bowing of legs, macrocephaly, frontal bossing, midfacial hypoplasia, small chest, redundant skin folds, recurrent infections, cor pulmonale, and restrictive pulmonary disease. Radiological features in achondroplasia Champagne glass pelvic inlet Trident hand Shoening of tubular bones with metaphyseal flaring Chevron deformity Ref: Nelson textbook of pediatrics 21st edition Pgno: 3726
Achondroplasia
Mucopolysaccharidosis
Osteopetrosis
Cleidocranial dysostosis
Genetic and genetic disorders