All cause Reticulocytosis EXCEPT:
Ans. (a) Aplastic anemiaRef: Robbiris pathology 9th ed. /631* Aplastic anemia is characterized by destruction of bone marrow and thereby reduction in pluri-potent stem cells and their progeny.Henceforth the production of reticulocytes is less.* Thalassemia and sickle cells are hemolytic anemias having extra-vascular hemolysis and thereby reticulocytosis.* In chronic blood loss the loss of RBC provoke the bone marrow to be more aggressive and release reticulocytes in circulation.* REMEMBER: Reticulocytopenia may be a result of viral Parvovirus B19 infection, which invades and destroys red blood cell precursors and halts the red cell production.
Aplastic anemia
Thalassemia
Sickle cell anemia
Chronic blood loss
Hemolytic anemia