Which statement about first order kinetics is TRUE?
In first order/exponential kinetics: Rate of elimination is propoional to the plasma drug concentration Clearence and tl/2 remains constant Constant fraction of the drug is eliminated in unit time Most of the drugs follow first order kinetics Zero order/linear kinetics Rate of elimination remains constant irrespective of the plasma drug concentration. CL decreases with increase in plasma drug concentration Constant amount of the drug is eliminated in unit time
Constant amount of drug is eliminated
Rate of elimination remains constant
Rate of elimination is directly propoional to drug concentration
Free drug concentration increases after successive doses