In pemphigus circulating antibodies attack:
Pemphigus

Is a skin and mucous membrane disease with autoimmune etiology.
Characterized histologically by intradermal blisters circulating IgG (IgG1 and IgG4) antibody against keratinocyte cell surface (attack Desmoglein 1 and 3).
Desmoglein 1&2.
Desmoglein1&3.
Desmoglein1&4.
Desmoglein2&4.