Extended activity of ii-lactamases inactivate ?
Ans. is 'a' i.e., Cephalosporins-III generation ESBL are lactamases that mediate resistance (by hydrolyzing) to extended spectrum (third generation) cephalosporins, penicillins and monobactams (e.g. aztreonam).
Cephalosporins-III generation
Macrolides
Quinolone
Aminoglycosides