How does chlamydia differ from other usual bacteria?
Ans. is 'c' i.e., Contains inclusion body Chlamydia produces basophilic (intracytoplasmic) inclusion bodies in infected cells in contrast to eosinophilic inclusion bodies produced by most viruses and hence they are sometimes referred to as Basophilic viruses. Unique propeies of chlamydiae are Chlamydia is an obligate intracellular parasite. This means they can survive only by establishig residence inside animal cells They need their host's ATP as an energy source for their own cellular activity. They are energy parasites using a cell membrane transpo system that uses ATP from the host system and gives out ADP. This obligate intracellular existence makes it impossible to culture these organisms on nonliving aificial media. Due to their small size and failure to grow in cell - free media they were considered to be viruses. Chlamydiae grows in cultures of a variety of eukaryotic cell lines Mc Coy or HeLa cells. It may be necessary to treat cells with polyanionic compounds such as DEAD-dextran to reduce the electrostatic barrier to infection. Antimetabolite such as cycloheximide is added to our competition for host cell amino acid pools. All types of chlamydiae proliferate in embryonated eggs paiculary in the yolk sac. The special features in structure and chemical composition of chlamydiae are: The outer cell wall resembles the cell wall of gram negative bacteria It has a relatively high lipid content It is rigid but it does not contain typical bacterial peptidoglycan; perhaps it contain a tetrapeptide linked matrix. N Acetylmuramic acid also appears to be absent from chlamydiae cell wall.
Lack cell wall
Cannot grow in cell free culture media
Contains inclusion body
None of the above