The drug used to stop the growth of prostate in a 70 year old male with Benign hyperplasia of prostate is
Ans. (c) FinasterideRef. Pharmacology Gobittd Sparsh /135Most of the actions of testosterone are mediated by its conversion to DHT by 5-alpha reductase. Important amongst these are growth of prostate, male pattern baldness and hirsutism in females. Finasteride and dutasteride are 5- alpha reductase inhibitors useful in the treatment of BHP, male pattern baldness and hirsutism by reducing the production of DHT.Note: Flutamide and Nilutamide act as antagonists of androgen receptors. These are useful for the treatment of prostatic carcinoma. Flutamide can cause gynaecomastia and reversible liver damage.
Spironolactone
Ketoconazole
Finasteride
Flutamide
Anti-Neoplastic Agents