Expansile lytic lesion at skull base typically involving clivus with specks of calcification is suggestive of NOT RELATED-RADIO
It is a destructive bone tumour believed to arise from ectopic remnants of notochord/ notochord cell rest.Its maximum incidence between 50-70 years.It is locally malignant with strong tendency to recur after excision.Predilection for sacral (50%) and cranial (40%) regions (the extreme ends of the axial skeleton); In sacrum at s4 and s5 and in cranium basisphenoid (clivus and dorsal aspect of sella)Above sacrum and below c2, chordomas are rare.Radiologically appears as a oval or lobulated well-defined purely lytic mass in midline, which may contain calcification and a soft tissue component.Recurrence rate is high but it metastasis occurs late.Chordoma at the base of skull carry best prognosis
Osteosarcoma
Secondaries in bone
Secondaries in bone
Fibrous histiocytoma
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