A 5 yr old male child presented with H/O recurrent infections. O/E the child has rashes as shown below. Routine blood investigation reveal patient has low platelets. Which of the following diagnosis is possible?
Wiskott Aldrich syndrome Etiopathogenesis: X linked recessive disorder Defect in WASP gene (Chr Xp11) Clinical: Characterized by recurrent infections, eczema like rash & thrombocytopenia Prolonged bleeding from circumcision site Bloody diarrhea Streptococcus pneumoniae & other bacteria having polysaccharide capsules cause otitis media, pneumonia, meningitis & sepsis Investigation findings: Thrombocytopenia with small sized platelets IgM: low IgE & IgA: elevated
Job syndrome
Wiskott Aldrich syndrome
Measles
Henoch Schonlein purpura
Paediatrics