Datasets:

lamm-mit

/

protein_secondary_structure_from_PDB

like 1

Follow

LAMM: MIT Laboratory for Atomistic and Molecular Mechanics 43

3SCM

NYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQGKLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSAGCEMYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGTSATVQMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPSSAHGHRQLVCHVSGFYPKPVWVMWMRGDQEQQGTHRGDFLPNADETWYLQATLDVEAGEEAGLACRVKHSSLGGQDIILYWGSLHHILDAQKMVWNHIQKTPQIQVYSRHPPENGKPNILNCYVTQFHPPHIEIQMLKNGKKIPKVEMSDMSFSKDWSFYILAHTEFTPTETDTYACRVKHASMAEPKTVYWDRDMTQVEQSPQSLVVRQGENSVLQCNYSVTPDNHLRWFKQDTGKGLVSLTVLVDQKDKTSNGRYSATLDKDAKHSTLHITATLLDDTATYICVVGDRGSALGRLHFGAGTQLIVIPDIQNPDPAVYQLRDSKSSDCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSACANAFNNIPEDTFFGGIITQTPKFLIGQEGQKLTLKCQQNFNHDTMYWYRQDSGKGLRLIYYSYGAGSTEKGDLSEGYDASREKKSSFSLTVTSAQKNEMAVFLCASGSLLDVREVFFGKGTRLTVVEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAW

~EEEEEEEEEEE~SSS~EEEEEEEEETTEEEEEE~TT~SS~EESSTTTTTT~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHSTTTS~SSEEEEEEEEEEE~TTS~EEEEEEEEETTEEEEEEETTEEEE~TT~~GGGHHHHHHHHT~HHHHHHHHHHHHTHHHHHHHHHHHHTHHHHT~~B~~EEEEEEEE~SSTTEEEEEEEEEEEBSS~~EEEEEETTEE~TT~EE~~~EE~TTS~EEEEEEEEEETT~~TTEEEEEE~GGGTT~~EEEETT~HHHHHHHHTT~~~~~~S~~EEEEEESS~~~TTS~EEEEEEEEEESSS~~EEEEEETTEE~S~~EE~~~EE~TT~~EEEEEEEEE~~~SS~~EEEEEE~TT~SS~EEEE~~TT~~~EEEE~SEEEEETTS~EEEEEEE~~SS~~EEEEEEE~TTS~~EEEEEE~SSEEEEEETTEEEEEETTTTEEEEEESS~~GGGGSEEEEEEES~SSTT~~EEE~~~BEEEEE~~~SS~~~EEE~~~~TTT~~~EEE~~~SS~~~~~~SSSS~EE~~~EEEEETTTTEEEEEE~EE~~~SS~~~~~~TT~~~~~~EEEE~SEEEE~TT~~EEEEEEE~S~~SEEEEEEEETTTEEEEEEEESSTT~~EE~TT~TTEEEEEEETTEEEEEESS~~TT~EEEEEEEEEETTEEEEEEE~~~EEEEE~S~GGG~B~~EEEEE~~~HHHHHHHSEEEEEEEEEEEBSS~EEEEEEETTEE~~SSEEE~SS~EESSTTSTT~~EEEEEEEEEEHHHHH~TTS~EEEEEEE~~B~SSS~~~~SS~~~BSEEEEEEE~

N Y T F R C L Q M S S F A N R S W S R T D S V V W L G D L Q T H R W S N D S A T I S F T K P W S Q G K L S N Q Q W E K L Q H M F Q V Y R V S F T R D I Q E L V K M M S P K E D Y P I E I Q L S A G C E M Y P G N A S E S F L H V A F Q G K Y V V R F W G T S W Q T V P G A P S W L D L P I K V L N A D Q G T S A T V Q M L L N D T C P L F V R G L L E A G K S D L E K Q E K P V A W L S S V P S S A H G H R Q L V C H V S G F Y P K P V W V M W M R G D Q E Q Q G T H R G D F L P N A D E T W Y L Q A T L D V E A G E E A G L A C R V K H S S L G G Q D I I L Y W G S L H H I L D A Q K M V W N H I Q K T P Q I Q V Y S R H P P E N G K P N I L N C Y V T Q F H P P H I E I Q M L K N G K K I P K V E M S D M S F S K D W S F Y I L A H T E F T P T E T D T Y A C R V K H A S M A E P K T V Y W D R D M T Q V E Q S P Q S L V V R Q G E N S V L Q C N Y S V T P D N H L R W F K Q D T G K G L V S L T V L V D Q K D K T S N G R Y S A T L D K D A K H S T L H I T A T L L D D T A T Y I C V V G D R G S A L G R L H F G A G T Q L I V I P D I Q N P D P A V Y Q L R D S K S S D C L F T D F D S Q T N V S Q S K D S D V Y I T D K C V L D M R S M D F K S N S A V A W S A C A N A F N N I P E D T F F G G I I T Q T P K F L I G Q E G Q K L T L K C Q Q N F N H D T M Y W Y R Q D S G K G L R L I Y Y S Y G A G S T E K G D L S E G Y D A S R E K K S S F S L T V T S A Q K N E M A V F L C A S G S L L D V R E V F F G K G T R L T V V E D L K N V F P P E V A V F E P S E A E I S H T Q K A T L V C L A T G F Y P D H V E L S W W V N G K E V H S G V C T D P Q P L K E Q P A L N D S R Y A L S S R L R V S A T F W Q N P R N H F R C Q V Q F Y G L S E N D E W T Q D R A K P V T Q I V S A E A W

BS

UNSTRUCTURED

1UL9

MLYHLFVNNQVKLQNDFKPESVAAIRSSAFNSKGGTTVFNFLSAGENILLHISIRPGENVIVFNSRLKNGAWGPEERIPYAEKFRPPNPSITVIDHGDRFQIRFDYGTSIYYNKRIKENAAAIAYNAENSLFSSPVTVDVHGLLPPLPPAMLYHLFVNNQVKLQNDFKPESVAAIRSSAFNSKGGTTVFNFLSAGENILLHISIRPGENVIVFNSRLKNGAWGPEERIPYAEKFRPPNPSITVIDHGDRFQIRFDYGTSIYYNKRIKENAAAIAYNAENSLFSSPVTVDVHGLLPPLPPA

~EEEE~TTEEEEEEEEE~TT~EEEEE~S~B~TT~~~EEEEEE~TT~~EEEEEEEEGGGTEEEEEEE~TTS~~~~~EEEE~TT~~~TTS~EEEEEE~SSEEEEE~SSS~~EEEE~SS~S~EEEEEEEESS~SB~SSEEEEEESS~~~~~~~~EEEE~TTEEEEEEEEE~TT~EEEEE~S~B~TT~~~EEEEEE~TT~~EEEEEEEETTTTEEEEEEE~TTS~~~~~EEEE~SS~~~TTS~EEEEEE~SSEEEEE~SSSS~EEEEHHH~S~EEEEEEEESS~SB~SSEEEEEESS~~~~~~~

M L Y H L F V N N Q V K L Q N D F K P E S V A A I R S S A F N S K G G T T V F N F L S A G E N I L L H I S I R P G E N V I V F N S R L K N G A W G P E E R I P Y A E K F R P P N P S I T V I D H G D R F Q I R F D Y G T S I Y Y N K R I K E N A A A I A Y N A E N S L F S S P V T V D V H G L L P P L P P A M L Y H L F V N N Q V K L Q N D F K P E S V A A I R S S A F N S K G G T T V F N F L S A G E N I L L H I S I R P G E N V I V F N S R L K N G A W G P E E R I P Y A E K F R P P N P S I T V I D H G D R F Q I R F D Y G T S I Y Y N K R I K E N A A A I A Y N A E N S L F S S P V T V D V H G L L P P L P P A

BS

UNSTRUCTURED

4HNZ

TTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKLENKIGEFPNQLTRAAVELAKEWRTDRALRRLEASLIVCSAEETLEIDGQGNVITPEADGIVAIGSGGTFAKAAARALIDVDGYDAEKIARKAMRIATDIDVFSNEHWDVEVLEHTTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKLENKIGEFPNQLTRAAVELAKEWRTDRALRRLEASLIVCSAEETLEIDGQGNVITPEADGIVAIGSGGTFAKAAARALIDVDGYDAEKIARKAMRIATDIDVFSNEHWDVEVLEHTTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKLENKIGEFPNQLTRAAVELAKEWRTDRALRRLEASLIVCSAEETLEIDGQGNVITPEADGIVAIGSGGTFAKAAARALIDVDGYDAEKIARKAMRIATDIDVFSNEHWDVEVLEHTTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKLENKIGEFPNQLTRAAVELAKEWRTDRALRRLEASLIVCSAEETLEIDGQGNVITPEADGIVAIGSGGTFAKAAARALIDVDGYDAEKIARKAMRIATDIDVFSNEHWDVEVLEHTTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKLENKIGEFPNQLTRAAVELAKEWRTDRALRRLEASLIVCSAEETLEIDGQGNVITPEADGIVAIGSGGTFAKAAARALIDVDGYDAEKIARKAMRIATDIDVFSNEHWDVEVLEHTTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKLENKIGEFPNQLTRAAVELAKEWRTDRALRRLEASLIVCSAEETLEIDGQGNVITPEADGIVAIGSGGTFAKAAARALIDVDGYDAEKIARKAMRIATDIDVFSNEHWDVEVLEHTTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKLENKIGEFPNQLTRAAVELAKEWRTDRALRRLEASLIVCSAEETLEIDGQGNVITPEADGIVAIGSGGTFAKAAARALIDVDGYDAEKIARKAMRIATDIDVFSNEHWDVEVLEHTTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKLENKIGEFPNQLTRAAVELAKEWRTDRALRRLEASLIVCSAEETLEIDGQGNVITPEADGIVAIGSGGTFAKAAARALIDVDGYDAEKIARKAMRIATDIDVFSNEHWDVEVLEHTTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKLENKIGEFPNQLTRAAVELAKEWRTDRALRRLEASLIVCSAEETLEIDGQGNVITPEADGIVAIGSGGTFAKAAARALIDVDGYDAEKIARKAMRIATDIDVFSNEHWDVEVLEHTTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKLENKIGEFPNQLTRAAVELAKEWRTDRALRRLEASLIVCSAEETLEIDGQGNVITPEADGIVAIGSGGTFAKAAARALIDVDGYDAEKIARKAMRIATDIDVFSNEHWDVEVLEHTTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKLENKIGEFPNQLTRAAVELAKEWRTDRALRRLEASLIVCSAEETLEIDGQGNVITPEADGIVAIGSGGTFAKAAARALIDVDGYDAEKIARKAMRIATDIDVFSNEHWDVEVLEHTTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKLENKIGEFPNQLTRAAVELAKEWRTDRALRRLEASLIVCSAEETLEIDGQGNVITPEADGIVAIGSGGTFAKAAARALIDVDGYDAEKIARKAMRIATDIDVFSNEHWDVEVLEH

~~EEEEEETTEEEEEEE~~EEETTTEEEES~~~~EEEEETTEEEEEEE~HHHHHHHHHHHHHHHHHSTT~HHHHHHHHHHHHHH~HHHHT~~EEEEEE~SS~EEEEETT~~EE~~~TT~EEEESTTHHHHHHHHHHHTT~TT~~HHHHHHHHHHHHHHHBTTS~S~EEEEEE~~~~EEEEEETTEEEEEEE~~EEETTTEEEES~~~~EEEEETTEEEEEEE~HHHHHHHHHHHHHHHHHSTT~HHHHHHHHHHHHHH~HHHHT~~EEEEEE~SS~EEEEETT~~EE~~~TT~EEEESTTHHHHHHHHHHHTT~TT~~HHHHHHHHHHHHHHHBTT~~S~EEEEEE~~~~EEEEEETTEEEEEEE~~EEETTTEEEES~~~~EEEEETTEEEEEEE~HHHHHHHHHHHHHHHHHSTT~HHHHHHHHHHHHHH~HHHHT~~EEEEEE~SS~EEEEETT~~EE~~~TT~EEEESTTHHHHHHHHHHHTT~TT~~HHHHHHHHHHHHHHHBTT~~S~EEEEEE~~~~EEEEEETTEEEEEEE~~EEETTTEEEES~~~~EEEEETTEEEEEEE~HHHHHHHHHHHHHHHHHSTT~HHHHHHHHHHHHHH~TTGGG~~EEEEEE~SS~EEEEETT~~EE~~~TT~EEEESTTHHHHHHHHHHHTTSTT~~HHHHHHHHHHHHHHHBTTS~S~EEEEEE~~~~EEEEEETTEEEEEEE~~EEETTTEEEES~~~~EEEEETTEEEEEEE~HHHHHHHHHHHHHHHHHSTT~HHHHHHHHHHHHHH~HHHHT~~EEEEEE~SS~EEEEETT~~EE~~~TT~EEEESTTHHHHHHHHHHHTTSTT~~HHHHHHHHHHHHHHHBTTS~S~EEEEEE~~~~EEEEEETTEEEEEEE~~EEETTTEEEES~~~~EEEEETTEEEEEEE~HHHHHHHHHHHHHHHHHSTT~HHHHHHHHHHHHHH~TTGGG~~EEEEEE~SS~EEEEETT~~EE~~~TT~EEEESTTHHHHHHHHHHHTTSTT~~HHHHHHHHHHHHHHHBTT~~S~EEEEEE~~~~EEEEEETTEEEEEEE~~EEETTTEEEES~~~~EEEEETTEEEEEEE~HHHHHHHHHHHHHHHHHSTT~HHHHHHHHHHHHHH~TTGGG~~EEEEEE~SS~EEEEETT~~EE~~~TT~EEEESTTHHHHHHHHHHHTTSTT~~HHHHHHHHHHHHHHHBTTS~S~EEEEEE~~~~EEEEEETTEEEEEEE~~EEETTTEEEES~~~~EEEEETTEEEEEEE~HHHHHHHHHHHHHHHHHSTT~HHHHHHHHHHHHHH~HHHHT~~EEEEEE~SS~EEEEETT~~EE~~~TT~EEEESTTHHHHHHHHHHHTT~TT~~HHHHHHHHHHHHHHHBTT~~S~EEEEEE~~~~EEEEEETTEEEEEEE~~EEETTTEEEES~~~~EEEEETTEEEEEEE~HHHHHHHHHHHHHHHHHSTT~HHHHHHHHHHHHHH~HHHHT~~EEEEEE~SS~EEEEETT~~EE~~~TT~EEEESTTHHHHHHHHHHHTT~TT~~HHHHHHHHHHHHHHHBTTS~S~EEEEEE~~~~EEEEEETTEEEEEEE~~EEETTTEEEES~~~~EEEEETTEEEEEEE~HHHHHHHHHHHHHHHHHSTT~HHHHHHHHHHHHHH~HHHHT~~EEEEEE~SS~EEEEETT~~EE~~~TT~EEEESTTHHHHHHHHHHHTT~TT~~HHHHHHHHHHHHHHHBTTS~S~EEEEEE~~~~EEEEEETTEEEEEEE~~EEETTTEEEES~~~~EEEEETTEEEEEEE~HHHHHHHHHHHHHHHHHSTT~HHHHHHHHHHHHHH~TTGGG~~EEEEEE~SS~EEEEETT~~EE~~~TT~EEEESTTHHHHHHHHHHHTTSTT~~HHHHHHHHHHHHHHHBTTS~S~EEEEEE~~~~EEEEEETTEEEEEEE~~EEETTTEEEES~~~~EEEEETTEEEEEEE~HHHHHHHHHHHHHHHHHSTT~HHHHHHHHHHHHHH~TTGGG~~EEEEEE~SS~EEEEETT~~EE~~~TT~EEEESTTHHHHHHHHHHHTTSTT~~HHHHHHHHHHHHHHHBTTS~S~EEEEEE~~

T T I L S V R K G D T V V L L G D R Q V T L G E R I V A K S S A C K L R R I N D D V V I G F A G S T A D A I S L M E K L E N K I G E F P N Q L T R A A V E L A K E W R T D R A L R R L E A S L I V C S A E E T L E I D G Q G N V I T P E A D G I V A I G S G G T F A K A A A R A L I D V D G Y D A E K I A R K A M R I A T D I D V F S N E H W D V E V L E H T T I L S V R K G D T V V L L G D R Q V T L G E R I V A K S S A C K L R R I N D D V V I G F A G S T A D A I S L M E K L E N K I G E F P N Q L T R A A V E L A K E W R T D R A L R R L E A S L I V C S A E E T L E I D G Q G N V I T P E A D G I V A I G S G G T F A K A A A R A L I D V D G Y D A E K I A R K A M R I A T D I D V F S N E H W D V E V L E H T T I L S V R K G D T V V L L G D R Q V T L G E R I V A K S S A C K L R R I N D D V V I G F A G S T A D A I S L M E K L E N K I G E F P N Q L T R A A V E L A K E W R T D R A L R R L E A S L I V C S A E E T L E I D G Q G N V I T P E A D G I V A I G S G G T F A K A A A R A L I D V D G Y D A E K I A R K A M R I A T D I D V F S N E H W D V E V L E H T T I L S V R K G D T V V L L G D R Q V T L G E R I V A K S S A C K L R R I N D D V V I G F A G S T A D A I S L M E K L E N K I G E F P N Q L T R A A V E L A K E W R T D R A L R R L E A S L I V C S A E E T L E I D G Q G N V I T P E A D G I V A I G S G G T F A K A A A R A L I D V D G Y D A E K I A R K A M R I A T D I D V F S N E H W D V E V L E H T T I L S V R K G D T V V L L G D R Q V T L G E R I V A K S S A C K L R R I N D D V V I G F A G S T A D A I S L M E K L E N K I G E F P N Q L T R A A V E L A K E W R T D R A L R R L E A S L I V C S A E E T L E I D G Q G N V I T P E A D G I V A I G S G G T F A K A A A R A L I D V D G Y D A E K I A R K A M R I A T D I D V F S N E H W D V E V L E H T T I L S V R K G D T V V L L G D R Q V T L G E R I V A K S S A C K L R R I N D D V V I G F A G S T A D A I S L M E K L E N K I G E F P N Q L T R A A V E L A K E W R T D R A L R R L E A S L I V C S A E E T L E I D G Q G N V I T P E A D G I V A I G S G G T F A K A A A R A L I D V D G Y D A E K I A R K A M R I A T D I D V F S N E H W D V E V L E H T T I L S V R K G D T V V L L G D R Q V T L G E R I V A K S S A C K L R R I N D D V V I G F A G S T A D A I S L M E K L E N K I G E F P N Q L T R A A V E L A K E W R T D R A L R R L E A S L I V C S A E E T L E I D G Q G N V I T P E A D G I V A I G S G G T F A K A A A R A L I D V D G Y D A E K I A R K A M R I A T D I D V F S N E H W D V E V L E H T T I L S V R K G D T V V L L G D R Q V T L G E R I V A K S S A C K L R R I N D D V V I G F A G S T A D A I S L M E K L E N K I G E F P N Q L T R A A V E L A K E W R T D R A L R R L E A S L I V C S A E E T L E I D G Q G N V I T P E A D G I V A I G S G G T F A K A A A R A L I D V D G Y D A E K I A R K A M R I A T D I D V F S N E H W D V E V L E H T T I L S V R K G D T V V L L G D R Q V T L G E R I V A K S S A C K L R R I N D D V V I G F A G S T A D A I S L M E K L E N K I G E F P N Q L T R A A V E L A K E W R T D R A L R R L E A S L I V C S A E E T L E I D G Q G N V I T P E A D G I V A I G S G G T F A K A A A R A L I D V D G Y D A E K I A R K A M R I A T D I D V F S N E H W D V E V L E H T T I L S V R K G D T V V L L G D R Q V T L G E R I V A K S S A C K L R R I N D D V V I G F A G S T A D A I S L M E K L E N K I G E F P N Q L T R A A V E L A K E W R T D R A L R R L E A S L I V C S A E E T L E I D G Q G N V I T P E A D G I V A I G S G G T F A K A A A R A L I D V D G Y D A E K I A R K A M R I A T D I D V F S N E H W D V E V L E H T T I L S V R K G D T V V L L G D R Q V T L G E R I V A K S S A C K L R R I N D D V V I G F A G S T A D A I S L M E K L E N K I G E F P N Q L T R A A V E L A K E W R T D R A L R R L E A S L I V C S A E E T L E I D G Q G N V I T P E A D G I V A I G S G G T F A K A A A R A L I D V D G Y D A E K I A R K A M R I A T D I D V F S N E H W D V E V L E H T T I L S V R K G D T V V L L G D R Q V T L G E R I V A K S S A C K L R R I N D D V V I G F A G S T A D A I S L M E K L E N K I G E F P N Q L T R A A V E L A K E W R T D R A L R R L E A S L I V C S A E E T L E I D G Q G N V I T P E A D G I V A I G S G G T F A K A A A R A L I D V D G Y D A E K I A R K A M R I A T D I D V F S N E H W D V E V L E H

AH

BS

1QGM

VIHCDAATICPDGTTCSLSPYGVWYCSPFS

~B~HSSSS~B~SS~EEEE~TTS~EEEE~~~

V I H C D A A T I C P D G T T C S L S P Y G V W Y C S P F S

UNSTRUCTURED

BS

5LAR

ERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPL

~~~~EEEEEETTEEEEEETTEEEEEEEGGGSSSEEEEEEETTTTEEEEEEE~SSTTSSHHHHHHHHHHHHHHHH~~STTB~~~SEEE~S~SSGGG~~~~EEEEE~~SEEHHHHHTTS~~~HHHHHHHHHHHHHHHHHHHHTT~~~~~~~GGGEEE~TT~~EEE~~SS~~~~SGGGGGS~~S~~TT~~HHHHTT~~~~~THHHHHHHHHHHHHHHHSS~SS~~SSHHHHHHHHHHHH~S~~HHHHTT~~~HHHHHHHHHS~~~~~~~GGGTSTTS~HHHHHHHHHHS~SSGGGS~~HHHHHTSGGGTTT~~TTS~~~~~~~~~GGGG~~~~HHHHHHHHHHHHHT~~~~~~

E R P T F Y R Q E L N K T I W E V P E R Y Q N L S P V G S G A Y G S V C A A F D T K T G H R V A V K K L S R P F Q S I I H A K R T Y R E L R L L K H M K H E N V I G L L D V F T P A R S L E E F N D V Y L V T H L M G A D L N N I V K C Q K L T D D H V Q F L I Y Q I L R G L K Y I H S A D I I H R D L K P S N L A V N E D C E L K I L D F G L A R H T D D E M T G Y V A T R W Y R A P E I M L N W M H Y N Q T V D I W S V G C I M A E L L T G R T L F P G T D H I D Q L K L I L R L V G T P G A E L L K K I S S E S A R N Y I Q S L A Q M P K M N F A N V F I G A N P L A V D L L E K M L V L D S D K R I T A A Q A L A H A Y F A Q Y H D P D D E P V A D P Y D Q S F E S R D L L I D E W K S L T Y D E V I S F V P P P L

AH

UNSTRUCTURED

5CFC

GVDNAEKGKVSDDNASTDFVAEPVKLPENQTRVSFFYDRSTLSSVLQSTSDVSSKFTPSTAKNLQNSILLTPLPSDIVNNSVLPEQERWISFASPTTQKPPYKTKQDWNFIMFSPFTYYKCDLEVTLSKNDRETISSVVRYVPCGAPSDLSDQTMPQTPSLADTRDPHMWVVGQGTTNQISFVIPYTSPLSVLPSVWFNGFSNFDNSSRFGVAPNADFGRLLLQGQGTFSVHYRYKKMRVFCPRPTVFIPWPSPFPVTVREHAGTFFSTTPDTTVPVYGNTISTPFDYMCGEFTDLLSLCKIPTFLGNLDSNKKRIPYFSATNSTPATPLVTYQVTLSCSCMANSMLAAVARNFNQYRGSLNYLFVFTGSAMTKGKFLISYTPPGAGEPKTLDQAMQATYAIWDLGLNSSYNFTVPFISPTHYRQTSYNTPTITSVDGWLTVWQLTPLTYPLGVPNDSHILTLVSGGDDFTLRMPVTFTKYVPQSDRVSSDTAGNTATNTQSTVGRLFGFGQRHKGKHPASCADTATDKVLAAERYYTIKLASWTKTQESFDHIRVPLPHALAGENGGVFSSTLRRHYLCKCGWRIQVQCNASQFHAGSLLVFMAPEFDTSNHSTEVEPRADTAFKVDANWQKHAQILTGHAYVNTTTKVNVPLALNHQNFWQWTTYPHQILNLRTNTTCDLEVPYVNVCPTSSWTQHANWTLVIAVLTPLQYSQGSATTIEITASIQPVKPVFNGLRHTVVGNEGVIINNYYSNQYQNSIDLSAN

~EE~GGGS~~~~~~TTTTSS~~~~~~~~~TTBHHHHH~S~EEEEEEEE~S~SSS~~~~~EETTEESEEE~~SS~EE~~SS~SS~EE~SEE~BSSSSS~~S~BSSB~~HHHHHS~~EEEEEEEEEEEEEESSSS~~EEEEEEE~TT~~~~~~~~SSTTS~GGGSSSS~EEEEESTTS~SEEEEEE~~~~SSSSEESS~B~B~SSTTS~S~TB~~TT~SS~EEEEESSEEEEEEEEEEEEEEEEE~~~~~~~~~~~~~~~~~TTTT~~~TT~S~~~~BSS~S~EE~~~TT~~~EE~BTHHHHTS~EE~~EE~TTS~EESEEEE~SS~~SS~SEEEESSTT~GGGTTSHHHHHHTTEEEEES~EEEEEEE~S~TT~EEEEEEEEE~SSS~S~~SHHHHTTSEEEEEE~SSS~EEEEEE~~~~SSSSEES~~SS~~TTT~~~EEEEEEEEEEE~~TTS~S~EEEEEEEEE~TT~EEEEE~~~~~~~~~~TT~EEEEETTEEEEESS~~~EEEGGG~~~~~~~~TT~~S~~B~~~TTTSS~EEEEEEEE~TT~~TT~EEEEEETGGGSSGGGHHHHHHHTTEEEEEEEEEEEEE~~~~TT~EEEEEEEEEET~~~S~~SSSS~~~TTTSS~~~SS~B~SGGGTT~~~SS~TTGGGG~~EETT~~~GGGGGGSSEEEEETTT~SEEEEEE~~~~SSSSB~GGGB~~EEEEEEEEEEEE~~TTS~~~EEEEEEEEEEEEEEEEE~S~~~~~~~~SS~~SS~HHHHS~EE~~~~

G V D N A E K G K V S D D N A S T D F V A E P V K L P E N Q T R V S F F Y D R S T L S S V L Q S T S D V S S K F T P S T A K N L Q N S I L L T P L P S D I V N N S V L P E Q E R W I S F A S P T T Q K P P Y K T K Q D W N F I M F S P F T Y Y K C D L E V T L S K N D R E T I S S V V R Y V P C G A P S D L S D Q T M P Q T P S L A D T R D P H M W V V G Q G T T N Q I S F V I P Y T S P L S V L P S V W F N G F S N F D N S S R F G V A P N A D F G R L L L Q G Q G T F S V H Y R Y K K M R V F C P R P T V F I P W P S P F P V T V R E H A G T F F S T T P D T T V P V Y G N T I S T P F D Y M C G E F T D L L S L C K I P T F L G N L D S N K K R I P Y F S A T N S T P A T P L V T Y Q V T L S C S C M A N S M L A A V A R N F N Q Y R G S L N Y L F V F T G S A M T K G K F L I S Y T P P G A G E P K T L D Q A M Q A T Y A I W D L G L N S S Y N F T V P F I S P T H Y R Q T S Y N T P T I T S V D G W L T V W Q L T P L T Y P L G V P N D S H I L T L V S G G D D F T L R M P V T F T K Y V P Q S D R V S S D T A G N T A T N T Q S T V G R L F G F G Q R H K G K H P A S C A D T A T D K V L A A E R Y Y T I K L A S W T K T Q E S F D H I R V P L P H A L A G E N G G V F S S T L R R H Y L C K C G W R I Q V Q C N A S Q F H A G S L L V F M A P E F D T S N H S T E V E P R A D T A F K V D A N W Q K H A Q I L T G H A Y V N T T T K V N V P L A L N H Q N F W Q W T T Y P H Q I L N L R T N T T C D L E V P Y V N V C P T S S W T Q H A N W T L V I A V L T P L Q Y S Q G S A T T I E I T A S I Q P V K P V F N G L R H T V V G N E G V I I N N Y Y S N Q Y Q N S I D L S A N

BS

UNSTRUCTURED

1OY9

DRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPMLTSVRPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVGYDWSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRK

~~HHHHHHHHHHHHHHHHHHHTSS~~~SS~~~S~~EEEEEEE~SS~~HHHHHHHTHHHHHHS~~~~SS~SEEE~EEESSSEEEEEEE~~TT~~HHHHHHHHHTTGGGSGGGS~HHHHSS~~EEEE~~S~EEEEEEEEESSS~~~TTHHHHHHTTTTHHHHHHTTTEEEEEESS~~EEEEEEE~HHHHHTTT~~HHHHHHHHTTSS~~~~~~BSS~SS~~TT~~~~~B~~~~~~~~SHHHHTT~EEEEETTTEEEEHHHHEEEEEEES~~S~EEETTSSEE~~EEEEE~SS~~THHHHHHHHHHHTTTGGG~~TTEEEE~~S~SHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~~~TTTTTTTTTTHHHHHHHHHHHHTTTT~~S~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS~~~THHHHHHHHHHHHHHHHHHHHHHTTTHHHHTS~BTTBHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS~~~HHHHHHHHHHHTHHHHHHHHHHH~~HHHHHHHHHHHHHHHHHHHSS~~~SS~~~~~S~~EEEEE~STT~~HHHHHHHHHHHHHHHHTS~TTTEEE~~EEET~~SS~~SSSEEEEE~EE~~TTTS~SSSSSHHHHHHHHHHHHTTS~SSEE~~B~~~SS~SS~~SSB~~EEEE~~SS~~HHHHHHHHHHHHHHHHH~~~~~B~~B~S~~~~~EEEEEE~HHHHHHHT~~HHHHHHHHHHHHT~EEEEEEEETTEEEEEEE~~~GGGGSSGGGGTT~~EEETTTEEE~HHHHEEEEEE~~~SEEEEETTEEEEEE~~B~~SS~~THHHHHHHHHHHTTS~TT~~~~~~~THHHHHHHHHHHHHHHHTSSSSTTSSHHHHGGGHHHHHHHHHHHHHHHSS~~S~HHHHHHHHHHHHHHHHHHHHHHHHHHTTTSSS~~~TTTTHHHHHTTTHHHHHHHHHHHHHHSHHHHTT~~SS~SHHHHHHHHHHHHHHHHHHHHTTTSSSSHHHHHHHTS~~

D R P I F A W V I A I I I M L A G G L A I L K L P V A Q Y P T I A P P A V T I S A S Y P G A D A K T V Q D T V T Q V I E Q N M N G I D N L M Y M S S N S D S T G T V Q I T L T F E S G T D A D I A Q V Q V Q N K L Q L A M P L L P Q E V Q Q Q G V S V E K S S S S F L M V V G V I N T D G T M T Q E D I S D Y V A A N M K D A I S R T S G V G D V Q L F G S Q Y A M R I W M N P N E L N K F Q L T P V D V I T A I K A Q N A Q V A A G Q L G G T P P V K G Q Q L N A S I I A Q T R L T S T E E F G K I L L K V N Q D G S R V L L R D V A K I E L G G E N Y D I I A E F N G Q P A S G L G I K L A T G A N A L D T A A A I R A E L A K M E P F F P S G L K I V Y P Y D T T P F V K I S I H E V V K T L V E A I I L V F L V M Y L F L Q N F R A T L I P T I A V P V V L L G T F A V L A A F G F S I N T L T M F G M V L A I G L L V D D A I V V V E N V E R V M A E E G L P P K E A T R K S M G Q I Q G A L V G I A M V L S A V F V P M A F F G G S T G A I Y R Q F S I T I V S A M A L S V L V A L I L T P A L C A T M L K F G W F N R M F E K S T H H Y T D S V G G I L R S T G R Y L V L Y L I I V V G M A Y L F V R L P S S F L P D E D Q G V F M T M V Q L P A G A T Q E R T Q K V L N E V T H Y Y L T K E K N N V E S V F A V N G F G F A G R G Q N T G I A F V S L K D W A D R P G E E N K V E A I T M R A T R A F S Q I K D A M V F A F N L P A I V E L G T A T G F D F E L I D Q A G L G H E K L T Q A R N Q L L A E A A K H P M L T S V R P N G L E D T P Q F K I D I D Q E K A Q A L G V S I N D I N T T L G A A W G G S Y V N D F I D R G R V K K V Y V M S E A K Y R M L P D D I G D W Y V R A A D G Q M V P F S A F S S S R W E Y G S P R L E R Y N G L P S M E I L G Q A A P G K S T G E A M E L M E Q L A S K L P T G V G Y D W S G N Q A P S L Y A I S L I V V F L C L A A L Y E S W S I P F S V M L V V P L G V I G A L L A A T F R G L T N D V Y F Q V G L L T T I G L S A K N A I L I V E F A K D L M D K E G K G L I E A T L D A V R M R L R P I L M T S L A F I L G V M P L V I S T G A G S G A Q N A V G T G V M G G M V T A T V L A I F F V P V F F V V V R R R F S R K

AH

UNSTRUCTURED

4CG2

ANPYERGPNPTDALLEARSGPFSVSEENVSRLSASGFGGGTIYYPRENNTYGAVAISPGYTGTEASIAWLGERIASHGFVVITIDTITTLDQPDSRAEQLNAALNHMINRASSTVRSRIDSSRLAVMGHSMGGGGSLRLASQRPDLKAAIPLTPWHLNKNWSSVTVPTLIIGADLDTIAPVATHAKPFYNSLPSSISKAYLELDGATHFAPNIPNKIIGKYSVAWLKRFVDNDTRYTQFLCPGPRLFGEVEEYRSTCPFYP

~~TT~~SS~~~HHHHHSSS~SS~EEEEEE~TTT~SSS~~EEEEEESS~S~EEEEEEE~~TT~~GGGTHHHHHHHHTTT~EEEEE~~SSTT~~HHHHHHHHHHHHHHHHHTS~HHHHTTEEEEEEEEEEETHHHHHHHHHHHH~TT~SEEEEES~~~S~~~~TT~~S~EEEEEETT~SSS~TTTTHHHHHHHS~TTS~EEEEEETT~~TTGGGS~~HHHHHHHHHHHHHHHS~~GGGHHHHSS~~~~TTTEEEEEE~TT~~~

A N P Y E R G P N P T D A L L E A R S G P F S V S E E N V S R L S A S G F G G G T I Y Y P R E N N T Y G A V A I S P G Y T G T E A S I A W L G E R I A S H G F V V I T I D T I T T L D Q P D S R A E Q L N A A L N H M I N R A S S T V R S R I D S S R L A V M G H S M G G G G S L R L A S Q R P D L K A A I P L T P W H L N K N W S S V T V P T L I I G A D L D T I A P V A T H A K P F Y N S L P S S I S K A Y L E L D G A T H F A P N I P N K I I G K Y S V A W L K R F V D N D T R Y T Q F L C P G P R L F G E V E E Y R S T C P F Y P

AH

BS

4ES8

EELPDDLMNFKGTWEVSADGSSGRFFSKGATDSYVFHLIPAKDVKKPGWREHNEVKDSYIKIDKQSIAARYKTSTTAPYSVAFKVNTKSLIKDHDYKITFEQGQIASGITVDYRIGSAFNKTTDDSFKISDESKYASNVKIEGEEQGFKQREQGDKTISFRTLKEGPMSLVLLSKVEKKPQGDLDVEFKNLKIIDVTNPSQLDKGVAYVGNKNVQLTLKSDDGRTNFEGDEISLFNSRGELLQTVTVTKDQQNPISITLSEDQAKSLKNKEKLKVSIKQKQSKKTSKDFFFEVGIDPKVEAKELPDDLMNFKGTWEVSADGSSGRFFSKGATDSYVFHLIPAKDVKKPGWREHNEVKDSYIKIDKQSIAARYKTSTTAPYSVAFKVNTKSLIKDHDYKITFEQGQIASGITVDYRIGSAFNKTTDDSFKISDESKYASNVKIEGEEQGFKQREQGDKTISFRTLKEGPMSLVLLSKVEKKPQGDLDVEFKNLKIIDVTNPSQLDKGVAYVGNKNVQLTLKSDDGRTNFEGDEISLFNSRGELLQTVTVTKDQQNPISITLSEDQAKSLKNKEKLKVSIKQKQSKKTSKDFFFEVGIDPK

~~~~~~~EE~~S~~~TTSTT~~EEEEEET~~SEEEE~~~~GGGTT~SS~EE~TTT~SEEEEE~SSEEEEEE~TT~~SSEEEEEEEEE~~B~TT~EEEEEEEEEEE~TTEEEEEEEEE~~~SSTT~EEEGGGHHHHEEEEEETTB~SSSB~~~SEEEEEEEEESSSB~EEEEEEEEESS~~SS~EEEEEEEEEEEE~~~~~EEEEEE~BTT~~EEEEEEE~TT~~~~~TTEEEEEE~TT~~EEEEEE~~TT~~SSEEEE~~HHHHHH~~TT~EEEEEEEETTT~~B~~~EEEE~B~~~~~~~~~~~~~~EE~~S~~~TTSTT~~EEEEEETS~SEEEE~~~~GGGTT~SS~EE~TTT~SEEEEE~SSEEEEEE~TT~~SSEEEEEEEEES~B~TT~EEEEEEEEEEE~TTEEEEEEEEE~~~SSTT~EEEGGGHHHHEEEEEETTB~~SSB~~~~EEEEEEEEESSSB~EEEEEEEEESS~~SS~EEEEEEEEEEEE~~~~~EEEEEE~BTT~~EEEEEEE~SSS~~~~TTEEEEEE~TT~~EEEEEE~~TT~~SSEEEE~~HHHHHH~~TT~EEEEEEEETTT~~B~~~EEEE~B~~~~

E E L P D D L M N F K G T W E V S A D G S S G R F F S K G A T D S Y V F H L I P A K D V K K P G W R E H N E V K D S Y I K I D K Q S I A A R Y K T S T T A P Y S V A F K V N T K S L I K D H D Y K I T F E Q G Q I A S G I T V D Y R I G S A F N K T T D D S F K I S D E S K Y A S N V K I E G E E Q G F K Q R E Q G D K T I S F R T L K E G P M S L V L L S K V E K K P Q G D L D V E F K N L K I I D V T N P S Q L D K G V A Y V G N K N V Q L T L K S D D G R T N F E G D E I S L F N S R G E L L Q T V T V T K D Q Q N P I S I T L S E D Q A K S L K N K E K L K V S I K Q K Q S K K T S K D F F F E V G I D P K V E A K E L P D D L M N F K G T W E V S A D G S S G R F F S K G A T D S Y V F H L I P A K D V K K P G W R E H N E V K D S Y I K I D K Q S I A A R Y K T S T T A P Y S V A F K V N T K S L I K D H D Y K I T F E Q G Q I A S G I T V D Y R I G S A F N K T T D D S F K I S D E S K Y A S N V K I E G E E Q G F K Q R E Q G D K T I S F R T L K E G P M S L V L L S K V E K K P Q G D L D V E F K N L K I I D V T N P S Q L D K G V A Y V G N K N V Q L T L K S D D G R T N F E G D E I S L F N S R G E L L Q T V T V T K D Q Q N P I S I T L S E D Q A K S L K N K E K L K V S I K Q K Q S K K T S K D F F F E V G I D P K

BS

UNSTRUCTURED

2DH7

GSSGSSGQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPSGPSSG

~~~~~~~~SS~~SS~EEEEEE~~~TT~~HHHHHHHSTTTS~EEEEEEEE~SSS~SEEEEEEEEESSHHHHHHHHHHTTT~~~SSS~~~~B~~~~~~~~~~~~~~~

G S S G S S G Q K K D T S N H F H V F V G D L S P E I T T E D I K S A F A P F G K I S D A R V V K D M A T G K S K G Y G F V S F Y N K L D A E N A I V H M G G Q W L G G R Q I R T N W A T R K P P A P S G P S S G

UNSTRUCTURED

BS

4ECN

SQYGYVQFKLYKSTSSSAQKIKVVTHNGTTVSQTLLLNAYNANNAEYGLRSDKLQLLAGTYKIVGYYLYDGLDEVLLAGPAGDDNELTVVSGGLLEKALTVDAVPHGTVTFKLSKEGISTRAAGEYLFSNIRYVDVTVNSFNRVTTELKGKVTYKEDIGVATCDSAVWLPAGTYQVVAYTTYSQSGIKRSELETQSVRGESFTVIDNKLTKDANVPIQLKETAEYIKDYKALKAIWEALDGKNWRYYSGTINNTIHSLNWNFNKELDWGDQPGVDLDNNGRVTGLSLAGFGAKGRVPDAIGQLTELKVLSFGTHSETVSGRLFGDEELTPDSEERKHRIRHYKKFLDYDQRLNLSDLLQDAINRNPEKPIKKDSRISLKDTQIGNLTNRITFISKAIQRLTKLQIIYFANSPFTYDNIAVDWEDANSDYAKQYENEELSWSNLKDLTDVELYNCPNTQLPDFLYDLPELQSLNIACNRGISAAQLKADWTRLADDEDTGPKIQIFYGYNNLEEFPASASLQKVKLGLLDCVHNKVRHLEAFGTNVKLTDLKLDYNQIEEIPEDFCAFTDQVEGLGFSHNKLKYIPNIFNAKSVYVGSVDFSYNKIGSEGRNISCSDDYKGINASTVTLSYNEIQKFPTELFATGSPISTIILSNNLTSIPENSLKPKDGNYKNTYLLTTIDLRFNKLTSLSDDFRATTLPYLSNDVSYNCFSSFPTQPLNSSQLKAFGIRHQRDAEGNRILRQWPTGITTCPSLIQLQIGSNDIRKVDEKLTPQLYILDIADNPNISIDVTSVCPYIEAGYVLLYDKTQDIRGCDALGIER

~~EEEEEEEEE~~~~~~~~EEEE~~~SS~~~~EEEEEEE~~~~SSEEEEEE~~EEEESEEEE~~EEEEE~TT~~EEEEEE~~S~~EEEE~TT~EEEEEEE~~SS~EEEEEEEEEE~SSTTSS~~SS~STT~~EEEEE~~TTT~~~~EE~~~EE~~~~~~EEEEEEEEEEESEEE~~~EEEEEEEETTEEEEEEEEE~~~~~EEE~TTSEEEEEEEEE~~~~~~HHHHHHHHHHHHHHHTTGGG~~~~~SS~SS~~~~~S~~~SS~~~~~~~TTEEE~TTS~EEEEE~TTT~~EEEE~GGGGG~TT~~EEES~~TTHHHHTT~BTTB~~~~~~HHHHHHH~~~~~~~~~~GGGGS~HHHHHHHHT~~~~~~~~~~~~~~~TTTTT~~S~EEEEE~GGGGG~TT~~EEEEES~~~~GGGBSSS~S~TTSHHHHHHTTS~~~GGG~TT~~EEEEES~~~~~~~GGGGG~SS~~EEE~TT~TTS~HHHHHHHHHHHHH~TTTTTT~~EE~~~S~~~B~~~HHHHT~~~~~EEE~TTS~~~B~~~~~TTSEESEEE~~SS~~S~~~TTS~EE~TT~~EEE~~SS~~~S~~S~~~TT~S~~~EEE~~SS~TTTTSSS~S~~~~~~~~~~SEEE~~SS~~~S~~HHHHHTT~~~SEEE~~S~~~~~~TTSSS~TTS~~TTGGG~~EEE~~SS~~~~~~GGGSTTT~TT~~~~~~SS~~SS~~~GGGG~TT~~EEE~~~~B~TT~~B~~~~~~TTGGG~SS~~EEE~~SS~~~B~~S~~~SSS~EEE~~S~TT~EEE~GGGHHHHHT~~EEE~~TTSEEES~GGG~~~~

S Q Y G Y V Q F K L Y K S T S S S A Q K I K V V T H N G T T V S Q T L L L N A Y N A N N A E Y G L R S D K L Q L L A G T Y K I V G Y Y L Y D G L D E V L L A G P A G D D N E L T V V S G G L L E K A L T V D A V P H G T V T F K L S K E G I S T R A A G E Y L F S N I R Y V D V T V N S F N R V T T E L K G K V T Y K E D I G V A T C D S A V W L P A G T Y Q V V A Y T T Y S Q S G I K R S E L E T Q S V R G E S F T V I D N K L T K D A N V P I Q L K E T A E Y I K D Y K A L K A I W E A L D G K N W R Y Y S G T I N N T I H S L N W N F N K E L D W G D Q P G V D L D N N G R V T G L S L A G F G A K G R V P D A I G Q L T E L K V L S F G T H S E T V S G R L F G D E E L T P D S E E R K H R I R H Y K K F L D Y D Q R L N L S D L L Q D A I N R N P E K P I K K D S R I S L K D T Q I G N L T N R I T F I S K A I Q R L T K L Q I I Y F A N S P F T Y D N I A V D W E D A N S D Y A K Q Y E N E E L S W S N L K D L T D V E L Y N C P N T Q L P D F L Y D L P E L Q S L N I A C N R G I S A A Q L K A D W T R L A D D E D T G P K I Q I F Y G Y N N L E E F P A S A S L Q K V K L G L L D C V H N K V R H L E A F G T N V K L T D L K L D Y N Q I E E I P E D F C A F T D Q V E G L G F S H N K L K Y I P N I F N A K S V Y V G S V D F S Y N K I G S E G R N I S C S D D Y K G I N A S T V T L S Y N E I Q K F P T E L F A T G S P I S T I I L S N N L T S I P E N S L K P K D G N Y K N T Y L L T T I D L R F N K L T S L S D D F R A T T L P Y L S N D V S Y N C F S S F P T Q P L N S S Q L K A F G I R H Q R D A E G N R I L R Q W P T G I T T C P S L I Q L Q I G S N D I R K V D E K L T P Q L Y I L D I A D N P N I S I D V T S V C P Y I E A G Y V L L Y D K T Q D I R G C D A L G I E R

UNSTRUCTURED

BS

3VON

NPLVSERLELSVLYKEQQKIKDLHKKYSYIRKTRPDGNCFYRAFGFSHLEALLDDSKELQRFKAVSAKSKEDLVSQGFTEFTIEDFHNTFMDLIEQVEKQTSVADLLASFNDQSTSDYLVVYLRLLTSGYLQRESKFFEHFIEGGRTVKEFCQQEVEPMCKESDHIHIIALAQALSVSIQVEYMDPHIFPEGSEPKVYLLYRPGHYDILYGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNPLVSERLELSVLYKEDDNIYQQKIKDLHKKYSYIRKTRPDGNCFYRAFGFSHLEALLDDSKELQRFKAVSAKSKEDLVSQGFTEFTIEDFHNTFMDLIEQVEKQTSVADLLASFNDQSTSDYLVVYLRLLTSGYLQRESKFFEHFIEGGRTVKEFCQQEVEPMCKESDHIHIIALAQALSVSIQVEYNPHIFPEGSEPKVYLLYRPGHYDILYGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNPLVSERLELSVLYKEYANIYQQKIKDLHKKYSYIRKTRPDGNCFYRAFGFSHLEALLDDSKELQRFKAVSAKSKEDLVSQGFTEFTIEDFHNTFMDLIEQVEKQTSVADLLASFNDQSTSDYLVVYLRLLTSGYLQRESKFFEHFIEGGRTVKEFCQQEVEPMCKESDHIHIIALAQALSVSIQVEYMDPHIFPEGSEPKVYLLYRPGHYDILYKGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNPLVSERLELSVLYKENIYQQKIKDLHKKYSYIRKTRPDGNCFYRAFGFSHLEALLDDSKELQRFKAVSAKSKEDLVSQGFTEFTIEDFHNTFMDLIEQVEKQTSVADLLASFNDQSTSDYLVVYLRLLTSGYLQRESKFFEHFIEGGRTVKEFCQQEVEPMCKESDHIHIIALAQALSVSIQVEYMDNPHIFPEGSEPKVYLLYRPGHYDILYKVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNPLVSERLELSVLYKENIYQQKIKDLHKKYSYIRKTRPDGNCFYRAFGFSHLEALLDDSKELQRFKAVSAKSKEDLVSQGFTEFTIEDFHNTFMDLIEQVEKQTSVADLLASFNDQSTSDYLVVYLRLLTSGYLQRESKFFEHFIEGGRTVKEFCQQEVEPMCKESDHIHIIALAQALSVSIQVEYMDGTTNPHIFPEGSEPKVYLLYRPGHYDILYGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNPLVSERLELSVLYKEIYQQKIKDLHKKYSYIRKTRPDGNCFYRAFGFSHLEALLDDSKELQRFKAVSAKSKEDLVSQGFTEFTIEDFHNTFMDLIEQVEKQTSVADLLASFNDQSTSDYLVVYLRLLTSGYLQRESKFFEHFIEGGRTVKEFCQQEVEPMCKESDHIHIIALAQALSVSIQVETNPHIFPEGSEPKVYLLYRPGHYDILYGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMN

~~SB~~~EEGGGGGG~~HHHHHHHTT~~EEE~B~~SS~HHHHHHHHHHHHHTTT~HHHHHHHHHHHHHHHHHHHTTT~~HHHHHHHHHHHHHHHHHHHS~~~HHHHHHHHSSHHHHHHHHHHHHHHHHHHHHHTHHHHGGG~~TT~~HHHHHHHTTSSTT~~~~HHHHHHHHHHHT~~EEEEE~~~EEESSSS~~SEEEEEETTEEEEE~~~~~~HHHHHHHHHHHHHH~~SSSSEE~~BS~TT~TT~~EEEEEEE~~TTSTTTT~EEEEEEE~~TTTTTS~~EEEESB~~~~TTB~TTT~BB~SSSSHHHHT~~TT~~HHHHHHHHHHHTSSTTTTT~~~~~TT~B~~~HHHHHHHHHHHHS~~TTEEEEE~SS~TTEEEEEEE~~TTSTTTT~EEEEEEE~~TTTTSS~~EEEESS~~~~TTB~TT~BB~~GGGTTT~~TT~~HHHHHHHHHHHHHS~S~SS~~~SHHHHHHHS~HHHHHHHHHHHHHHHH~~~~~~HHHHHHHHHHHHHH~~TTSSEEEEESSTT~TT~~EEEEEEE~~TTSTTTT~EEEEEEE~~TTTTTS~~EEEESB~~~~TTB~TTT~BB~GGGSHHHHT~~SS~~HHHHHHHHHHHTSSTTTTTS~~~~TT~B~~~HHHHHHHHHHHHS~~TTEEEEEETTEEEEEEEEEE~~TTSTTTT~EEEEEEE~~TTTTSS~~EEEESS~~~~TTB~TT~BB~~GGGTTS~~TTS~HHHHHHHHHHHHHS~~SS~SS~~SHHHHHHHTHHHHHHHHHHHHHHHS~~~~~~~HHHHHHHHHHHHHH~~TT~SEEEEESSTT~TT~~EEEEEEEB~TTSSSBT~EEEEEEE~~TTTTSS~~EEEESB~~~~TTB~TTT~BB~TTTSHHHHT~~TT~~HHHHHHHHHHHTTSTTTTTS~~~~SS~B~~~HHHHHHHHHHHHS~~TTEEEEEETTEEEEEEEEEE~~TTSTTTT~EEEEEEE~~TTTTTS~~EEEESS~~~BTTB~TTSBB~~GGGTTT~~TTS~HHHHHHHHHHHHHS~~TTS~~~SHHHHHHHH~HHHHHHHHHHHHHHHS~~~~SB~~~EEGGGGTT~~~~TTHHHHHHHHTT~~EEE~B~SSS~HHHHHHHHHHHTGGGT~HHHHHHHHHHHHHHHHHHHTTT~~HHHHHHHHHHHHHTTHHHHTT~~HHHHHHHHSSHHHHHHHHHHHHHHHHHHHHHTHHHHGGG~~TT~~HHHHHHHHTSSTT~~~~HHHHHHHHHHTT~~EEEE~~EEEESSSS~~SEEEEEETTEEEEE~~~~~~HHHHHHHHHHHHHH~TTTSSEEEEES~TT~TT~~EEEEEEE~~TTSTTTT~EEEEEEE~~TTTTTS~~EEEESB~~~~TTS~SSS~~~~TTTSHHHHS~~TT~~HHHHHHHHHHGGGSHHHHT~~~~~SS~B~~~HHHHHHHHHHHHS~~TTEEEEE~SS~TTEEEEEEE~~TTSTTTT~EEEEEEE~~TTTTSS~~EEEESS~~~~TTB~TT~BB~~GGGTTT~~TT~~HHHHHHHHHHHHHS~~~~~SS~~HHHHHHHHSHHHHHHHHHHHHHHHS~~~~~~~HHHHHHHHHHHHHH~~TTSSEEEEESSTT~TT~~EEEEEEE~~TTSTTTT~EEEEEEE~~TTTTTS~~EEEESB~~~~TTB~TTT~BB~GGG~HHHHT~~TT~~HHHHHHHHHHHTTSHHHHTS~~~~TT~B~~~HHHHHHHHHHHHS~~TTEEEEE~SS~TTEEEEEEEB~TTSTTBT~EEEEEEE~~TTTTSS~~EEEESS~~~BTTB~TT~BB~~GGGTTS~~TT~~HHHHHHHHHHHHHS~~TTSSS~~HHHHHHHH~HHHHHHHHHHHHHHHS~~~~~~~HHHHHHHHHHHHHH~~TTSSEEEEESSTT~TT~~EEEEEEE~~SSSSSTT~EEEEEEE~~TTTTTS~~EEEESB~~~~TTB~TTT~BB~GGGSHHHHT~~TT~~HHHHHHHHHHHTTSTTTTTS~~~~SS~B~~~HHHHHHHHHHHHS~BTTEEEEE~SS~TTEEEEEEE~~TTSTTTT~EEEEEEE~~TTTTTS~~EEEESS~~~BTTB~TT~BB~~GGGTTS~~TTS~HHHHHHHHHHHHHS~~~~~SS~~HHHHHHHH~HHHHHHHHHHHHHHHT~~~~SB~~~EEGGGHHHH~~~TTTHHHHHHHTT~~EEE~B~SSS~HHHHHHHHHHHHHTTT~HHHHHHHHHHHHHHHHHHHHHT~~HHHHHHHHHHHHHHHHHHHTT~~HHHHHHHSS~HHHHHHHHHHHHHHHHHHHHHTHHHHGGG~~TT~~HHHHHHHHTSSTT~~~~HHHHHHHHHHTT~~EEEEE~~~EEESTTS~~SEEEEEETTEEEEEE~~~~~~HHHHHHHHHHHHHH~SSSSSEEEEES~TT~TT~~EEEEEEE~~SSSTTTT~EEEEEEE~~TTTTTS~~EEEESB~~~~TTB~TTT~BB~TTTSHHHHS~~TT~~HHHHHHHHHHHTTSHHHHT~~~~~SS~B~~~HHHHHHHHHHHHS~BTTEEEEE~SS~TTEEEEEEE~~TTSTTTT~EEEEEEE~~TTTTTS~~EEEESS~~~~TTB~TT~BB~~GGGTTT~~TT~~HHHHHHHHHHHHHS~~~~~TT~~HHHHHHHH~HHHHHHHHHHHHHHHS~~~~~~HHHHHHHHHHHHHH~~TTSSEEEEESSTT~TT~~EEEEEEE~~SSSTTSS~EEEEEEE~~TTTTTS~~EEEE~B~~~~TTB~TTT~BB~GGG~HHHHT~~TT~~HHHHHHHHHHTTSSHHHHTS~~~~TT~B~~~~HHHHHHHHHHHHS~~TTEEEEEETTEEEEEEEEEE~~TTSTTTTSEEEEEEE~~TTTTTS~~EEEESS~~~~TTB~TTSBB~~GGGTTT~~TTS~HHHHHHHHHHHHHS~~TT~TT~~SHHHHHHH~HHHHHHHHHHHHHHHS~~~~~~~HHHHHHHHHHHHHH~~TT~SEEEEES~TT~TT~~EEEEEEE~~TTSTTTT~EEEEEEE~~TTTTTS~~EEEESS~~~~TTB~TTT~BB~GGGSHHHHT~~TT~~HHHHHHHHHHTTSSTTTTT~~~~~SS~~~~~HHHHHHHHHHHHS~~TTEEEEEETTEEEEEEEEEE~~TTSTTTT~EEEEEEE~~TTTTTS~~EEEESS~~~BTTB~TT~BB~~GGGTTT~~TTS~HHHHHHHHHHHHHS~~~~SSS~~HHHHHHHH~HHHHHHHHHHHHHHHS~~~~SB~~~EESGGGTT~~~SSHHHHHHHTT~~EEE~B~SSS~HHHHHHHHHHHHHTTT~HHHHHHHHHHHHHHHHHHHTTT~~HHHHHHHHHHHHHHHHHHHTT~~HHHHHHHHS~HHHHHHHHHHHHHHHHHHHHHTHHHHGGG~~TT~~HHHHHHHHTSSTT~~~~HHHHHHHHHHTT~~EEEEE~~~EEEESTTS~~SEEEEEETTEEEEEE~~~~~HHHHHHHHHHHHHH~~SSSSEEEEES~TT~TT~~EEEEEEE~~SSSSS~S~EEEEEEE~~TTTTTS~~EEEESB~~~~TTB~TTT~BB~TTTSHHHHS~~TT~~HHHHHHHHHHHTTSHHHHT~~~~~SS~B~~~HHHHHHHHHHHHS~~TTEEEEEETTEEEEEEEEEE~~TTSTTTT~EEEEEEE~~TTTTTS~~EEEESS~~~~TTB~TT~BB~~GGGTTT~~TT~~HHHHHHHHHHHHHS~~~~~~SS~HHHHHHHH~HHHHHHHHHHHHHHHS~~~~~~HHHHHHHHHHHHHH~~TTSSEEEEESSTT~TT~~EEEEEEE~~TTSTTSS~EEEEEEE~~TTTTTS~~EEEESB~~~~TTB~TTT~BB~GGG~HHHHT~~TT~~HHHHHHHHHHHTTSHHHHSS~~~~TT~B~~~~HHHHHHHHHHHHS~BTTEEEEEETTEEEEEEEEEE~~TTSTTTT~EEEEEEE~~TTTTTS~~EEEESS~~~~TTB~TTSBB~~GGGTTS~~TT~~HHHHHHHHHHHHHS~~TT~SS~~SHHHHHHH~HHHHHHHHHHHHHHHS~~~~~~~HHHHHHHHHHHHHH~~TT~SEEEEES~TT~TT~~EEEEEEE~~TTSSSTT~EEEEEEE~~TTTTTS~~EEEESB~~~~TTB~TTT~BB~GGGSHHHHT~~TT~~HHHHHHHHHHHTTSTTTTTS~~~~TT~B~~~HHHHHHHHHHHHS~~TTEEEEEETTEEEEEEEEEE~~TTSTTTT~EEEEEEE~~TTTTTS~~EEEESS~~~BTTB~TT~BB~~GGGTTT~~TTS~HHHHHHHHHHHHHS~~~~~SS~~TTHHHHHHTHHHHHHHHHHHHHHHS~~~~SB~~~EEGGGGGG~~TTHHHHHHHHTT~~EEE~B~~SS~HHHHHHHHHHHHHTSS~HHHHHHHHHHHHHHHHHHHHTT~~HHHHHHHHHHHHHHHHHHHS~~~HHHHHTTSSSHHHHHHHHHHHHHHHHHHHHHTHHHHGGGS~SS~~HHHHHHHHTSSTT~~~~HHHHHHHHHHHT~~EEEEE~~~~~EEEEESTTS~~SEEEEEETTEEEEE~~~~~~HHHHHHHHHHHHHH~~SSSSEE~~BSSTT~TT~~EEEEEEE~~TTSTTTT~EEEEEEE~~TTTTSS~~EEEESB~~~~TTB~SSS~BB~TTTSTTTTT~~TT~~HHHHHHHHHHHTTSHHHHT~~~~~SS~B~~~HHHHHHHHHHHHS~~TTEEEEE~SS~TTEEEEEEE~~TTSTTTT~EEEEEEE~~TTTTSS~~EEEESS~~~~TTB~TT~BB~~GGGTTT~~TT~~HHHHHHHHHHHHHS~~~~~SSS~TTHHHHHH~HHHHHHHHHHHHHHHS~~~~~~HHHHHHHHHHHHHH~~TTSSEEEEESSTT~TT~~EEEEEEE~~SSSTTTT~EEEEEEE~~TTTTTS~~EEEESB~~~~TTB~TTT~BB~GGG~HHHHT~~TT~~HHHHHHHHHHGGGSTTTTTS~~~~TT~B~~~~HHHHHHHHHHHHS~~TTEEEEE~SS~SSEEEEEEE~~TTSTTTT~EEEEEEE~~TTTTSS~~EEEE~S~~~~TTB~TT~BB~~GGGTTS~~TT~~HHHHHHHHHHHHHS~~TT~TT~~HHHHHHHH~HHHHHHHHHHHHHHHS~~~~~~~HHHHHHHHHHHHHH~~TT~SEEEEESSTT~TT~~EEEEEEE~~TTSSSTT~EEEEEEE~~TTTTTS~~EEEESB~~~~TTB~TTT~BB~TTTSHHHHT~~TT~~HHHHHHHHHHHTTSTTTTTS~~~~SS~B~~~~HHHHHHHHHHHHS~BTTEEEEEETTEEEEEEEEEE~~TTSTTTT~EEEEEEE~~TTTTTS~~EEEESS~~~BTTB~TT~BB~~GGGTTT~~TTS~HHHHHHHHHHHHHS~~~~~SS~~HHHHHHHHTHHHHHHHHHHHHHHHS~~~~B~~~EESGGGTT~~~STTHHHHHTT~~EEE~B~SSS~SHHHHHHHHTTSSTTT~HHHHHHHHHHHHHHHHHHHTTT~~GGGSHHHHHHHHHHHHHHHTT~~HHHHHHHHSSHHHHHHHHHHHHHHHHHHHHHTHHHHGGG~~SS~~HHHHHHHHTSSSS~~~~HHHHHHHHHHTT~~EEE~~~~EEESSSS~~SEEEEEETTEEEEE~~~~~~HHHHHHHHHHHHHH~~TTSSEEEEES~TT~SS~~EEEEEEE~~TTSSSTT~EEEEEEE~~TTTTTS~~EEEESB~~~~TTB~TTT~BB~TTTSTTTSS~~TT~~HHHHHHHHHHGGGSTTTTT~~~~~TT~B~~~HHHHHHHHHHHHS~~TTEEEEE~SS~TTEEEEEEE~~TTSTTTT~EEEEEEE~~TTTTSS~~EEEE~S~~~~TTB~TT~BB~~GGGTTT~~TT~~HHHHHHHHHHHHHS~~~SS~~~~HHHHHHHHSHHHHHHHHHHHHHHHT~~~~~~HHHHHHHHHHHHHH~~TTSSEEEEESSTT~TT~~EEEEEEE~~TTSTTTT~EEEEEEE~~TTTTTS~~EEEESB~~~~TTB~TTT~BB~GGG~HHHHS~~TT~~HHHHHHHHHHHTTSTTTTTS~~~~TT~B~~~HHHHHHHHHHHHS~BTTEEEEE~SS~TTEEEEEEEB~TTSTTBT~EEEEEEE~~TTTTSS~~EEEESS~~~~TTB~TT~BB~~GGGTTT~~TT~~HHHHHHHHHHHHHS~~~~~TT~~HHHHHHHH~HHHHHHHHHHHHHHHS~~~~~~~HHHHHHHHHHHHHH~~TTSSEEEEES~TT~TT~~EEEEEEE~~TTSSSTT~EEEEEEE~~TTTTTS~~EEEESB~~~~TTB~TTT~BB~GGGSHHHHT~~TT~~HHHHHHHHHHHTTSTTTTTS~~~~SS~B~~~~HHHHHHHHHHHHS~~TTEEEEEETTEEEEEEEEEE~~TTSTTTT~EEEEEEE~~TTTTSS~~EEEE~S~~~~SSB~TTSBB~~GGGTTT~~TTS~HHHHHHHHHHHHHS~~TT~SS~~TTHHHHHHTHHHHHHHHHHHHHHHT~~

N P L V S E R L E L S V L Y K E Q Q K I K D L H K K Y S Y I R K T R P D G N C F Y R A F G F S H L E A L L D D S K E L Q R F K A V S A K S K E D L V S Q G F T E F T I E D F H N T F M D L I E Q V E K Q T S V A D L L A S F N D Q S T S D Y L V V Y L R L L T S G Y L Q R E S K F F E H F I E G G R T V K E F C Q Q E V E P M C K E S D H I H I I A L A Q A L S V S I Q V E Y M D P H I F P E G S E P K V Y L L Y R P G H Y D I L Y G V K V P R N F R L L E E L E E G Q K G V G D G T V S W G L E D D E D M T L T R W T G M I I G P P R T N Y E N R I Y S L K V E C G P K Y P E A P P S V R F V T K I N M N G I N N S S G M V D A R S I P V L A K W Q N S Y S I K V V L Q E L R R L M M S K E N M K L P Q P P E G Q T Y L P R R I I K E T Q R L L A E P V P G I K A E P D E S N A R Y F H V V I A G P Q D S P F E G G T F K L E L F L P E E Y P M A A P K V R F M T K I Y H P N V D K L G R I C L D I L K D K W S P A L Q I R T V L L S I Q A L L S A P N P D D P L A N D V A E Q W K T N E A Q A I E T A R A W T R L Y A M N V K V P R N F R L L E E L E E G Q K G V G D G T V S W G L E D D E D M T L T R W T G M I I G P P R T N Y E N R I Y S L K V E C G P K Y P E A P P S V R F V T K I N M N G I N N S S G M V D A R S I P V L A K W Q N S Y S I K V V L Q E L R R L M M S K E N M K L P Q P P E G Q T Y L P R R I I K E T Q R L L A E P V P G I K A E P D E S N A R Y F H V V I A G P Q D S P F E G G T F K L E L F L P E E Y P M A A P K V R F M T K I Y H P N V D K L G R I C L D I L K D K W S P A L Q I R T V L L S I Q A L L S A P N P D D P L A N D V A E Q W K T N E A Q A I E T A R A W T R L Y A M N G V K V P R N F R L L E E L E E G Q K G V G D G T V S W G L E D D E D M T L T R W T G M I I G P P R T N Y E N R I Y S L K V E C G P K Y P E A P P S V R F V T K I N M N G I N N S S G M V D A R S I P V L A K W Q N S Y S I K V V L Q E L R R L M M S K E N M K L P Q P P E G Q T Y L P R R I I K E T Q R L L A E P V P G I K A E P D E S N A R Y F H V V I A G P Q D S P F E G G T F K L E L F L P E E Y P M A A P K V R F M T K I Y H P N V D K L G R I C L D I L K D K W S P A L Q I R T V L L S I Q A L L S A P N P D D P L A N D V A E Q W K T N E A Q A I E T A R A W T R L Y A M N N P L V S E R L E L S V L Y K E D D N I Y Q Q K I K D L H K K Y S Y I R K T R P D G N C F Y R A F G F S H L E A L L D D S K E L Q R F K A V S A K S K E D L V S Q G F T E F T I E D F H N T F M D L I E Q V E K Q T S V A D L L A S F N D Q S T S D Y L V V Y L R L L T S G Y L Q R E S K F F E H F I E G G R T V K E F C Q Q E V E P M C K E S D H I H I I A L A Q A L S V S I Q V E Y N P H I F P E G S E P K V Y L L Y R P G H Y D I L Y G V K V P R N F R L L E E L E E G Q K G V G D G T V S W G L E D D E D M T L T R W T G M I I G P P R T N Y E N R I Y S L K V E C G P K Y P E A P P S V R F V T K I N M N G I N N S S G M V D A R S I P V L A K W Q N S Y S I K V V L Q E L R R L M M S K E N M K L P Q P P E G Q T Y L P R R I I K E T Q R L L A E P V P G I K A E P D E S N A R Y F H V V I A G P Q D S P F E G G T F K L E L F L P E E Y P M A A P K V R F M T K I Y H P N V D K L G R I C L D I L K D K W S P A L Q I R T V L L S I Q A L L S A P N P D D P L A N D V A E Q W K T N E A Q A I E T A R A W T R L Y A M N G V K V P R N F R L L E E L E E G Q K G V G D G T V S W G L E D D E D M T L T R W T G M I I G P P R T N Y E N R I Y S L K V E C G P K Y P E A P P S V R F V T K I N M N G I N N S S G M V D A R S I P V L A K W Q N S Y S I K V V L Q E L R R L M M S K E N M K L P Q P P E G Q T Y L P R R I I K E T Q R L L A E P V P G I K A E P D E S N A R Y F H V V I A G P Q D S P F E G G T F K L E L F L P E E Y P M A A P K V R F M T K I Y H P N V D K L G R I C L D I L K D K W S P A L Q I R T V L L S I Q A L L S A P N P D D P L A N D V A E Q W K T N E A Q A I E T A R A W T R L Y A M N G V K V P R N F R L L E E L E E G Q K G V G D G T V S W G L E D D E D M T L T R W T G M I I G P P R T N Y E N R I Y S L K V E C G P K Y P E A P P S V R F V T K I N M N G I N N S S G M V D A R S I P V L A K W Q N S Y S I K V V L Q E L R R L M M S K E N M K L P Q P P E G Q T Y L P R R I I K E T Q R L L A E P V P G I K A E P D E S N A R Y F H V V I A G P Q D S P F E G G T F K L E L F L P E E Y P M A A P K V R F M T K I Y H P N V D K L G R I C L D I L K D K W S P A L Q I R T V L L S I Q A L L S A P N P D D P L A N D V A E Q W K T N E A Q A I E T A R A W T R L Y A M N N P L V S E R L E L S V L Y K E Y A N I Y Q Q K I K D L H K K Y S Y I R K T R P D G N C F Y R A F G F S H L E A L L D D S K E L Q R F K A V S A K S K E D L V S Q G F T E F T I E D F H N T F M D L I E Q V E K Q T S V A D L L A S F N D Q S T S D Y L V V Y L R L L T S G Y L Q R E S K F F E H F I E G G R T V K E F C Q Q E V E P M C K E S D H I H I I A L A Q A L S V S I Q V E Y M D P H I F P E G S E P K V Y L L Y R P G H Y D I L Y K G V K V P R N F R L L E E L E E G Q K G V G D G T V S W G L E D D E D M T L T R W T G M I I G P P R T N Y E N R I Y S L K V E C G P K Y P E A P P S V R F V T K I N M N G I N N S S G M V D A R S I P V L A K W Q N S Y S I K V V L Q E L R R L M M S K E N M K L P Q P P E G Q T Y L P R R I I K E T Q R L L A E P V P G I K A E P D E S N A R Y F H V V I A G P Q D S P F E G G T F K L E L F L P E E Y P M A A P K V R F M T K I Y H P N V D K L G R I C L D I L K D K W S P A L Q I R T V L L S I Q A L L S A P N P D D P L A N D V A E Q W K T N E A Q A I E T A R A W T R L Y A M N V K V P R N F R L L E E L E E G Q K G V G D G T V S W G L E D D E D M T L T R W T G M I I G P P R T N Y E N R I Y S L K V E C G P K Y P E A P P S V R F V T K I N M N G I N N S S G M V D A R S I P V L A K W Q N S Y S I K V V L Q E L R R L M M S K E N M K L P Q P P E G Q T Y G L P R R I I K E T Q R L L A E P V P G I K A E P D E S N A R Y F H V V I A G P Q D S P F E G G T F K L E L F L P E E Y P M A A P K V R F M T K I Y H P N V D K L G R I C L D I L K D K W S P A L Q I R T V L L S I Q A L L S A P N P D D P L A N D V A E Q W K T N E A Q A I E T A R A W T R L Y A M N G V K V P R N F R L L E E L E E G Q K G V G D G T V S W G L E D D E D M T L T R W T G M I I G P P R T N Y E N R I Y S L K V E C G P K Y P E A P P S V R F V T K I N M N G I N N S S G M V D A R S I P V L A K W Q N S Y S I K V V L Q E L R R L M M S K E N M K L P Q P P E G Q T Y L P R R I I K E T Q R L L A E P V P G I K A E P D E S N A R Y F H V V I A G P Q D S P F E G G T F K L E L F L P E E Y P M A A P K V R F M T K I Y H P N V D K L G R I C L D I L K D K W S P A L Q I R T V L L S I Q A L L S A P N P D D P L A N D V A E Q W K T N E A Q A I E T A R A W T R L Y A M N N P L V S E R L E L S V L Y K E N I Y Q Q K I K D L H K K Y S Y I R K T R P D G N C F Y R A F G F S H L E A L L D D S K E L Q R F K A V S A K S K E D L V S Q G F T E F T I E D F H N T F M D L I E Q V E K Q T S V A D L L A S F N D Q S T S D Y L V V Y L R L L T S G Y L Q R E S K F F E H F I E G G R T V K E F C Q Q E V E P M C K E S D H I H I I A L A Q A L S V S I Q V E Y M D N P H I F P E G S E P K V Y L L Y R P G H Y D I L Y K V K V P R N F R L L E E L E E G Q K G V G D G T V S W G L E D D E D M T L T R W T G M I I G P P R T N Y E N R I Y S L K V E C G P K Y P E A P P S V R F V T K I N M N G I N N S S G M V D A R S I P V L A K W Q N S Y S I K V V L Q E L R R L M M S K E N M K L P Q P P E G Q T Y L P R R I I K E T Q R L L A E P V P G I K A E P D E S N A R Y F H V V I A G P Q D S P F E G G T F K L E L F L P E E Y P M A A P K V R F M T K I Y H P N V D K L G R I C L D I L K D K W S P A L Q I R T V L L S I Q A L L S A P N P D D P L A N D V A E Q W K T N E A Q A I E T A R A W T R L Y A M N V K V P R N F R L L E E L E E G Q K G V G D G T V S W G L E D D E D M T L T R W T G M I I G P P R T N Y E N R I Y S L K V E C G P K Y P E A P P S V R F V T K I N M N G I N N S S G M V D A R S I P V L A K W Q N S Y S I K V V L Q E L R R L M M S K E N M K L P Q P P E G Q T Y G L P R R I I K E T Q R L L A E P V P G I K A E P D E S N A R Y F H V V I A G P Q D S P F E G G T F K L E L F L P E E Y P M A A P K V R F M T K I Y H P N V D K L G R I C L D I L K D K W S P A L Q I R T V L L S I Q A L L S A P N P D D P L A N D V A E Q W K T N E A Q A I E T A R A W T R L Y A M N G V K V P R N F R L L E E L E E G Q K G V G D G T V S W G L E D D E D M T L T R W T G M I I G P P R T N Y E N R I Y S L K V E C G P K Y P E A P P S V R F V T K I N M N G I N N S S G M V D A R S I P V L A K W Q N S Y S I K V V L Q E L R R L M M S K E N M K L P Q P P E G Q T Y L P R R I I K E T Q R L L A E P V P G I K A E P D E S N A R Y F H V V I A G P Q D S P F E G G T F K L E L F L P E E Y P M A A P K V R F M T K I Y H P N V D K L G R I C L D I L K D K W S P A L Q I R T V L L S I Q A L L S A P N P D D P L A N D V A E Q W K T N E A Q A I E T A R A W T R L Y A M N N P L V S E R L E L S V L Y K E N I Y Q Q K I K D L H K K Y S Y I R K T R P D G N C F Y R A F G F S H L E A L L D D S K E L Q R F K A V S A K S K E D L V S Q G F T E F T I E D F H N T F M D L I E Q V E K Q T S V A D L L A S F N D Q S T S D Y L V V Y L R L L T S G Y L Q R E S K F F E H F I E G G R T V K E F C Q Q E V E P M C K E S D H I H I I A L A Q A L S V S I Q V E Y M D G T T N P H I F P E G S E P K V Y L L Y R P G H Y D I L Y G V K V P R N F R L L E E L E E G Q K G V G D G T V S W G L E D D E D M T L T R W T G M I I G P P R T N Y E N R I Y S L K V E C G P K Y P E A P P S V R F V T K I N M N G I N N S S G M V D A R S I P V L A K W Q N S Y S I K V V L Q E L R R L M M S K E N M K L P Q P P E G Q T Y L P R R I I K E T Q R L L A E P V P G I K A E P D E S N A R Y F H V V I A G P Q D S P F E G G T F K L E L F L P E E Y P M A A P K V R F M T K I Y H P N V D K L G R I C L D I L K D K W S P A L Q I R T V L L S I Q A L L S A P N P D D P L A N D V A E Q W K T N E A Q A I E T A R A W T R L Y A M N V K V P R N F R L L E E L E E G Q K G V G D G T V S W G L E D D E D M T L T R W T G M I I G P P R T N Y E N R I Y S L K V E C G P K Y P E A P P S V R F V T K I N M N G I N N S S G M V D A R S I P V L A K W Q N S Y S I K V V L Q E L R R L M M S K E N M K L P Q P P E G Q T Y G L P R R I I K E T Q R L L A E P V P G I K A E P D E S N A R Y F H V V I A G P Q D S P F E G G T F K L E L F L P E E Y P M A A P K V R F M T K I Y H P N V D K L G R I C L D I L K D K W S P A L Q I R T V L L S I Q A L L S A P N P D D P L A N D V A E Q W K T N E A Q A I E T A R A W T R L Y A M N G V K V P R N F R L L E E L E E G Q K G V G D G T V S W G L E D D E D M T L T R W T G M I I G P P R T N Y E N R I Y S L K V E C G P K Y P E A P P S V R F V T K I N M N G I N N S S G M V D A R S I P V L A K W Q N S Y S I K V V L Q E L R R L M M S K E N M K L P Q P P E G Q T Y G L P R R I I K E T Q R L L A E P V P G I K A E P D E S N A R Y F H V V I A G P Q D S P F E G G T F K L E L F L P E E Y P M A A P K V R F M T K I Y H P N V D K L G R I C L D I L K D K W S P A L Q I R T V L L S I Q A L L S A P N P D D P L A N D V A E Q W K T N E A Q A I E T A R A W T R L Y A M N P L V S E R L E L S V L Y K E I Y Q Q K I K D L H K K Y S Y I R K T R P D G N C F Y R A F G F S H L E A L L D D S K E L Q R F K A V S A K S K E D L V S Q G F T E F T I E D F H N T F M D L I E Q V E K Q T S V A D L L A S F N D Q S T S D Y L V V Y L R L L T S G Y L Q R E S K F F E H F I E G G R T V K E F C Q Q E V E P M C K E S D H I H I I A L A Q A L S V S I Q V E T N P H I F P E G S E P K V Y L L Y R P G H Y D I L Y G V K V P R N F R L L E E L E E G Q K G V G D G T V S W G L E D D E D M T L T R W T G M I I G P P R T N Y E N R I Y S L K V E C G P K Y P E A P P S V R F V T K I N M N G I N N S S G M V D A R S I P V L A K W Q N S Y S I K V V L Q E L R R L M M S K E N M K L P Q P P E G Q T Y L P R R I I K E T Q R L L A E P V P G I K A E P D E S N A R Y F H V V I A G P Q D S P F E G G T F K L E L F L P E E Y P M A A P K V R F M T K I Y H P N V D K L G R I C L D I L K D K W S P A L Q I R T V L L S I Q A L L S A P N P D D P L A N D V A E Q W K T N E A Q A I E T A R A W T R L Y A M N V K V P R N F R L L E E L E E G Q K G V G D G T V S W G L E D D E D M T L T R W T G M I I G P P R T N Y E N R I Y S L K V E C G P K Y P E A P P S V R F V T K I N M N G I N N S S G M V D A R S I P V L A K W Q N S Y S I K V V L Q E L R R L M M S K E N M K L P Q P P E G Q T Y L P R R I I K E T Q R L L A E P V P G I K A E P D E S N A R Y F H V V I A G P Q D S P F E G G T F K L E L F L P E E Y P M A A P K V R F M T K I Y H P N V D K L G R I C L D I L K D K W S P A L Q I R T V L L S I Q A L L S A P N P D D P L A N D V A E Q W K T N E A Q A I E T A R A W T R L Y A M N G V K V P R N F R L L E E L E E G Q K G V G D G T V S W G L E D D E D M T L T R W T G M I I G P P R T N Y E N R I Y S L K V E C G P K Y P E A P P S V R F V T K I N M N G I N N S S G M V D A R S I P V L A K W Q N S Y S I K V V L Q E L R R L M M S K E N M K L P Q P P E G Q T Y G L P R R I I K E T Q R L L A E P V P G I K A E P D E S N A R Y F H V V I A G P Q D S P F E G G T F K L E L F L P E E Y P M A A P K V R F M T K I Y H P N V D K L G R I C L D I L K D K W S P A L Q I R T V L L S I Q A L L S A P N P D D P L A N D V A E Q W K T N E A Q A I E T A R A W T R L Y A M N

AH

UNSTRUCTURED

1I2O

TDKLTSLRQYTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVAWAKQQSNDRAQQIVDATDKLAVNIGLEILKLVPGRISTAVDARLSYDTEASIAKAKRLIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVSEIYQYYKEHGYETVVMGASFRNIGEILELAGCDRLTIAPALLKELAESEGAIERKLSYTGEVKARPARITESEFLWQHNQDPMAVDKLAEGIRKFAIDQEKLEKMIGDLLTDKLTSLRQYTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVAWAKQQSNDRAQQIVDATDKLAVNIGLEILKLVPGRISTAVDARLSYDTEASIAKAKRLIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVSEIYQYYKEHGYETVVMGASFRNIGEILELAGCDRLTIAPALLKELAESEGAIERKLSYTGEVKARPARITESEFLWQHNQDPMAVDKLAEGIRKFAIDQEKLEKMIGDLL

~BHHHHHTTTSEEEEE~S~HHHHHHH~~SEEE~~HHHHHHHTTSGGGHHHHHHHHHHHHHH~S~HHHHHHHHHHHHHHHHHHHHHTT~SS~EEEE~~GGGTT~HHHHHHHHHHHHHHHHHTT~~GGGEEEEEE~SHHHHHHHHHHHHTT~~EEEEEE~SHHHHHHHHHTT~SEEEEBSHHHHHHHHHHSS~~~~~GGG~HHHHHHHHHHHHHHHTT~~~EEEEB~~SSHHHHHTTTTSSEEEE~HHHHHHHHT~BS~~~~~~~~~S~~~~~~~~~~HHHHHHHHTT~HHHHHHHHHHHHHHHHHHHHHHHHHHTT~~BHHHHHTTTSEEEEE~S~HHHHHHH~~SEEE~~HHHHHHHTTSGGGHHHHHHHHHHHHHH~S~HHHHHHHHHHHHHHHHHHHHHTT~SS~EEEE~~GGGTT~HHHHHHHHHHHHHHHHHTT~~GGGEEEEEE~SHHHHHHHHHHHHTT~~EEEEEE~SHHHHHHHHHTT~SEEEEBSHHHHHHHHHHSS~~~~~GGG~HHHHHHHHHHHHHHHTT~~~EEEEB~~SSHHHHHTTTTSSEEEE~HHHHHHHHH~BS~~~~~~~~~S~~~~~~~~~~HHHHHHHHTT~HHHHHHHHHHHHHHHHHHHHHHHHHHTT~

T D K L T S L R Q Y T T V V A D T G D I A A M K L Y Q P Q D A T T N P S L I L N A A Q I P E Y R K L I D D A V A W A K Q Q S N D R A Q Q I V D A T D K L A V N I G L E I L K L V P G R I S T A V D A R L S Y D T E A S I A K A K R L I K L Y N D A G I S N D R I L I K L A S T W Q G I R A A E Q L E K E G I N C N L T L L F S F A Q A R A C A E A G V F L I S P F V G R I L D W Y K A N T D K K E Y A P A E D P G V V S V S E I Y Q Y Y K E H G Y E T V V M G A S F R N I G E I L E L A G C D R L T I A P A L L K E L A E S E G A I E R K L S Y T G E V K A R P A R I T E S E F L W Q H N Q D P M A V D K L A E G I R K F A I D Q E K L E K M I G D L L T D K L T S L R Q Y T T V V A D T G D I A A M K L Y Q P Q D A T T N P S L I L N A A Q I P E Y R K L I D D A V A W A K Q Q S N D R A Q Q I V D A T D K L A V N I G L E I L K L V P G R I S T A V D A R L S Y D T E A S I A K A K R L I K L Y N D A G I S N D R I L I K L A S T W Q G I R A A E Q L E K E G I N C N L T L L F S F A Q A R A C A E A G V F L I S P F V G R I L D W Y K A N T D K K E Y A P A E D P G V V S V S E I Y Q Y Y K E H G Y E T V V M G A S F R N I G E I L E L A G C D R L T I A P A L L K E L A E S E G A I E R K L S Y T G E V K A R P A R I T E S E F L W Q H N Q D P M A V D K L A E G I R K F A I D Q E K L E K M I G D L L

AH

UNSTRUCTURED

3WVA

ITVATAECFTHANIGLTIHKAAAGYEDFEFKYLFSEEDLKLKNVRVISAFVPSIIGVEKLLDIKLPEPDFNYKYAKAYSEEKDLEVAKLAEGLKKKLNVNISIGSTAGVGRGAICILTDNNRYLFTSDVYANLITFENIKERQKNGIEKGIKRFLEILKKEYFITVATAECFTHANIGLTIHKAAAGYEDFEFKYLFSEEDLKLKNVRVISAFVPSIIGVEKLLDIKLPEPDFNYKYAKAYSEEKDLEVAKLAEGLKKKLNVNISIGSTAGVGRGAICILTDNNRYLFTSDVYANLITFENIKERQKNGIEKGIKRFLEILKKEYF

~EEEEEESTTTTHHHHHHHHHHTT~S~~TTGGG~~HHHHH~~~~EEEE~~~~~HHHHHHHHT~~~~~~SS~~SSS~~~~HHHHHHHHH~~HHHHHHHT~SEEEEEE~SEES~EEEEE~SS~EEEE~~S~~EETTT~TTHHHHHHHHHHHHHHHHHHHHHHHH~~EEEEEESTTTTHHHHHHHHHHTT~S~~TTGGGS~HHHHH~~~~EEEE~~~~SHHHHHHHHT~~~~~~SS~~SSS~~~BHHHHHHHHH~~HHHHHHHT~SEEEEEE~SEES~EEEEE~SS~EEEE~~S~~EETTT~TTHHHHHHHHHHHHHHHHHHHHHHHH~

I T V A T A E C F T H A N I G L T I H K A A A G Y E D F E F K Y L F S E E D L K L K N V R V I S A F V P S I I G V E K L L D I K L P E P D F N Y K Y A K A Y S E E K D L E V A K L A E G L K K K L N V N I S I G S T A G V G R G A I C I L T D N N R Y L F T S D V Y A N L I T F E N I K E R Q K N G I E K G I K R F L E I L K K E Y F I T V A T A E C F T H A N I G L T I H K A A A G Y E D F E F K Y L F S E E D L K L K N V R V I S A F V P S I I G V E K L L D I K L P E P D F N Y K Y A K A Y S E E K D L E V A K L A E G L K K K L N V N I S I G S T A G V G R G A I C I L T D N N R Y L F T S D V Y A N L I T F E N I K E R Q K N G I E K G I K R F L E I L K K E Y F

AH

UNSTRUCTURED

4P2G

ASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLEDAKKEGPYDVVVLPGGNLGAQNLSESAAVKEILKEQENRKGLIAAIAGPTALLAHEIGFGSKVTTHPLAKDKMMNGGHYTYSENRVEKDGLILTSRGPGTSFEFALAIVEALNGKEVAAQVKAPLVLK

~~~EEEEEE~TT~~HHHHHHHHHHHHHTT~EEEEEETT~SS~EE~TTS~EE~~SEEHHHHHHT~~~SEEEE~~~HHHHHHHHT~HHHHHHHHHHHHTT~EEEE~~THHHHHHTT~STT~EE~~~GGGHHHHTTTS~SEE~~~SEEEETTEEEE~SGGGHHHHHHHHHHHHH~HHHHHHHHGGGT~~

A S K R A L V I L A K G A E E M E T V I P V D V M R R A G I K V T V A G L A G K D P V Q C S R D V V I C P D A S L E D A K K E G P Y D V V V L P G G N L G A Q N L S E S A A V K E I L K E Q E N R K G L I A A I A G P T A L L A H E I G F G S K V T T H P L A K D K M M N G G H Y T Y S E N R V E K D G L I L T S R G P G T S F E F A L A I V E A L N G K E V A A Q V K A P L V L K

AH

BS

1XO6

DIHTTAGKLADLRRRIEEATHAGSARAVEKQHAKGKLTARERIDLLLDEGSFVELDEFARHRSTNFGLDANRPYGDGVVTGYGTVDGRPVAVFSQDFTVFGGALGEVYGQKIVKVMDFALKTGCPVVGINDSGGARIQEGVASLGAYGEIFRRNTHASGVIPQISLVVGPCAGGAVYSPAITDFTVMVDQTSHMFITGPDVIKTVTGEDVGFEELGGARTHNSTSGVAHHMAGDEKDAVEYVKQLLSYLPSNNLSEPPAFPEEADLAVTDEDAELDTIVPDSANQPYDMHSVIEHVLDDAEFFETQPLFAPNILTGFGRVEGRPVGIVANQPMQFAGCLDITASEKAARFVRTCDAFNVPVLTFVDVPGFLPGVDQEHDGIIRRGAKLIFAYAEATVPLITVITRKAFGGAYDVMGSKHLGADLNLAWPTAQIAVMGAQGAVNILHRRTIADAGDDAEATRARLIQEYEDALLNPYTAAERGYVDAVIMPSDTRRHIVRGLRQLRTKRESLPPKKHGNIPLDIHTTAGKLADLRRRIEEATHAGSARAVEKQHAKGKLTARERIDLLLDEGSFVELDEFARHRSTNFGLDANRPYGDGVVTGYGTVDGRPVAVFSQDFTVFGGALGEVYGQKIVKVMDFALKTGCPVVGINDSGGARIQEGVASLGAYGEIFRRNTHASGVIPQISLVVGPCAGGAVYSPAITDFTVMVDQTSHMFITGPDVIKTVTGEDVGFEELGGARTHNSTSGVAHHMAGDEKDAVEYVKQLLSYLPSNNLSEPPAFPEEADLAVTDEDAELDTIVPDSANQPYDMHSVIEHVLDDAEFFETQPLFAPNILTGFGRVEGRPVGIVANQPMQFAGCLDITASEKAARFVRTCDAFNVPVLTFVDVPGFLPGVDQEHDGIIRRGAKLIFAYAEATVPLITVITRKAFGGAYDVMGSKHLGADLNLAWPTAQIAVMGAQGAVNILHRRTIADAGDDAEATRARLIQEYEDALLNPYTAAERGYVDAVIMPSDTRRHIVRGLRQLRTKRESLPPKKHGNIPLDIHTTAGKLADLRRRIEEATHAGSARAVEKQHAKGKLTARERIDLLLDEGSFVELDEFARHRSTNFGLDANRPYGDGVVTGYGTVDGRPVAVFSQDFTVFGGALGEVYGQKIVKVMDFALKTGCPVVGINDSGGARIQEGVASLGAYGEIFRRNTHASGVIPQISLVVGPCAGGAVYSPAITDFTVMVDQTSHMFITGPDVIKTVTGEDVGFEELGGARTHNSTSGVAHHMAGDEKDAVEYVKQLLSYLPSNNLSEPPAFPEEADLAVTDEDAELDTIVPDSANQPYDMHSVIEHVLDDAEFFETQPLFAPNILTGFGRVEGRPVGIVANQPMQFAGCLDITASEKAARFVRTCDAFNVPVLTFVDVPGFLPGVDQEHDGIIRRGAKLIFAYAEATVPLITVITRKAFGGAYDVMGSKHLGADLNLAWPTAQIAVMGAQGAVNILHRRTIADAGDDAEATRARLIQEYEDALLNPYTAAERGYVDAVIMPSDTRRHIVRGLRQLRTKRESLPPKKHGNIPLDIHTTAGKLADLRRRIEEATHAGSARAVEKQHAKGKLTARERIDLLLDEGSFVELDEFARHRSTNFGLDANRPYGDGVVTGYGTVDGRPVAVFSQDFTVFGGALGEVYGQKIVKVMDFALKTGCPVVGINDSGGARIQEGVASLGAYGEIFRRNTHASGVIPQISLVVGPCAGGAVYSPAITDFTVMVDQTSHMFITGPDVIKTVTGEDVGFEELGGARTHNSTSGVAHHMAGDEKDAVEYVKQLLSYLPSNNLSEPPAFPEEADLAVTDEDAELDTIVPDSANQPYDMHSVIEHVLDDAEFFETQPLFAPNILTGFGRVEGRPVGIVANQPMQFAGCLDITASEKAARFVRTCDAFNVPVLTFVDVPGFLPGVDQEHDGIIRRGAKLIFAYAEATVPLITVITRKAFGGAYDVMGSKHLGADLNLAWPTAQIAVMGAQGAVNILHRRTIADAGDDAEATRARLIQEYEDALLNPYTAAERGYVDAVIMPSDTRRHIVRGLRQLRTKRESLPPKKHGNIPLDIHTTAGKLADLRRRIEEATHAGSARAVEKQHAKGKLTARERIDLLLDEGSFVELDEFARHRSTNFGLDANRPYGDGVVTGYGTVDGRPVAVFSQDFTVFGGALGEVYGQKIVKVMDFALKTGCPVVGINDSGGARIQEGVASLGAYGEIFRRNTHASGVIPQISLVVGPCAGGAVYSPAITDFTVMVDQTSHMFITGPDVIKTVTGEDVGFEELGGARTHNSTSGVAHHMAGDEKDAVEYVKQLLSYLPSNNLSEPPAFPEEADLAVTDEDAELDTIVPDSANQPYDMHSVIEHVLDDAEFFETQPLFAPNILTGFGRVEGRPVGIVANQPMQFAGCLDITASEKAARFVRTCDAFNVPVLTFVDVPGFLPGVDQEHDGIIRRGAKLIFAYAEATVPLITVITRKAFGGAYDVMGSKHLGADLNLAWPTAQIAVMGAQGAVNILHRRTIADAGDDAEATRARLIQEYEDALLNPYTAAERGYVDAVIMPSDTRRHIVRGLRQLRTKRESLPPKKHGNIPLDIHTTAGKLADLRRRIEEATHAGSARAVEKQHAKGKLTARERIDLLLDEGSFVELDEFARHRSTNFGLDANRPYGDGVVTGYGTVDGRPVAVFSQDFTVFGGALGEVYGQKIVKVMDFALKTGCPVVGINDSGGARIQEGVASLGAYGEIFRRNTHASGVIPQISLVVGPCAGGAVYSPAITDFTVMVDQTSHMFITGPDVIKTVTGEDVGFEELGGARTHNSTSGVAHHMAGDEKDAVEYVKQLLSYLPSNNLSEPPAFPEEADLAVTDEDAELDTIVPDSANQPYDMHSVIEHVLDDAEFFETQPLFAPNILTGFGRVEGRPVGIVANQPMQFAGCLDITASEKAARFVRTCDAFNVPVLTFVDVPGFLPGVDQEHDGIIRRGAKLIFAYAEATVPLITVITRKAFGGAYDVMGSKHLGADLNLAWPTAQIAVMGAQGAVNILHRRTIADAGDDAEATRARLIQEYEDALLNPYTAAERGYVDAVIMPSDTRRHIVRGLRQLRTKRESLPPKKHGNIPL

~~SSHHHHHHHHHHHHHHHTT~S~HHHHHHHHHTT~~~HHHHHHHHS~TT~~EEESTT~~~~~~GGGGGG~~~TTTTEEEEEEEETTEEEEEEEE~TTSGGG~B~HHHHHHHHHHHHHHHHHT~~EEEEEEE~SB~GGGTHHHHHHHHHHHHHHHHTTTTS~EEEEEEEEEEGGGGHHHHHSSEEEEETTT~EEESS~HHHHHHHH~~~~~HHHHHBHHHHHHTSS~~SEEESSHHHHHHHHHHHHHHS~SSTTS~~~~~~~~~~~S~~HHHHHHHHHS~SSTT~~~~HHHHHHTTSGGG~~EEESTTS~TTEEEEEEEETTEEEEEEEE~TTTGGG~B~HHHHHHHHHHHHHHHHTT~~EEEEEEE~~B~~~HHHHHTTHHHHSHHHHHHHHH~~S~EEEEEEEEEEHHHHHHTT~GGGT~SEEEE~TT~EEESS~HHHHHHHHTHHHHHSS~TT~HHHHHHHHHHHHHHHSSSHHHHHHTSSSEE~~GGGHHHHHHHHHHHHTT~~~~~~~~S~~~~~~~~SSHHHHHHHHHHHHHHHTT~S~HHHHHHHHHTT~~~HHHHHHHHS~TT~~EEESTT~~~~~~GGGGGG~~~TTTTEEEEEEEETTEEEEEEEE~TTSGGG~B~HHHHHHHHHHHHHHHHHT~~EEEEE~~~SB~GGGTHHHHHHHHHHHHHHHHTTTTS~EEEEE~SEEEGGGGHHHHHSSEEEEETTT~EEESS~HHHHHHHH~~~~~HHHHHBHHHHHHTSS~~SEEESSHHHHHHHHHHHHHHS~SSTTS~~~~~~~~~~~S~~HHHHHTTTSS~SSTT~~~~HHHHHHTTSGGG~~EEESTTSSTTEEEEEEEETTEEEEEEEE~TTTGGG~B~HHHHHHHHHHHHHHHHTT~~EEEEEEE~~B~~~HHHHHTTHHHHHHHHHHHHHH~~S~EEEEEEEEEEHHHHHHTT~GGGT~SEEEE~TT~EEESS~HHHHHHHHTHHHHHS~~TTTTSSHHHHHHHHHHHHSSSHHHHHTTSSSEE~~GGGHHHHHHHHHHHHTT~~~~~~~~S~~~~~~~TTSHHHHHHHHHHHHHHHTT~S~HHHHHHHHHTT~~~HHHHHHHHS~TT~~EEESTT~~~~~~GGGGGG~~~TTTTEEEEEEEETTEEEEEEEE~TTSGGG~B~HHHHHHHHHHHHHHHHHT~~EEEEEEE~SB~GGGTHHHHHHHHHHHHHHHHTTTTS~EEEEEEEEEEGGGGHHHHHSSEEEEETTT~EEESS~HHHHHHHH~~~~~HHHHHBHHHHHHTSS~~SEEESSHHHHHHHHHHHHHTS~SSTTS~~~~~~~~~~~S~~HHHHHGGG~S~SSSS~~~~HHHHHHHHSGGG~~EEESTTSSTTEEEEEEEETTEEEEEEEE~TTSGGG~B~HHHHHHHHHHHHHHHHTT~~EEEEEEE~~B~~~HHHHHTTHHHHTHHHHHHHHH~~S~EEEEEEEEEEHHHHHHTT~GGGT~SEEEE~TT~EEESS~HHHHHHHHTHHHHHSS~TT~HHHHHHHHHHHHHHHSSSHHHHHHTSSSEE~~GGGHHHHHHHHHHHHTT~~~~~~~~S~~~~~~~~SSHHHHHHHHHHHHHHHTT~S~HHHHHHHHHTT~~~HHHHHHHHS~TT~~EEESTT~~~~~~GGGGGG~~~TTTTEEEEEEEETTEEEEEEEE~TTSGGG~B~HHHHHHHHHHHHHHHHHT~~EEEEEEE~SB~GGGTHHHHHHHHHHHHHHHHHTTTS~EEEEEEEEEEGGGGHHHHHSSEEEEETTT~EEESS~HHHHHHHH~~~~~HHHHHBHHHHHHTS~~~SEEESSHHHHHHHHHHHHHTS~SSTTS~~~~~~~~~~~S~~HHHHHGGGSS~SSTT~~~~HHHHHHHHSGGG~~EEESTTSSTTEEEEEEEETTEEEEEEEE~TTTGGG~B~HHHHHHHHHHHHHHHHTT~~EEEEEEE~~B~~~HHHHHTTHHHHHHHHHHHHHH~~S~EEEEEEEEEEHHHHHHTT~GGGT~SEEEE~TT~EEESS~HHHHHHHHTHHHHHS~STTHHHHHHHHHHHHHHHHSSSHHHHHHTSSSEE~~GGGHHHHHHHHHHHHTT~~~~~~~~S~~~~~~~~SSHHHHHHHHHHHHHHHTT~S~HHHHHHHHHTT~~~HHHHHHHHS~TT~~EEESTT~~~~~~GGGGGG~~~TTTTEEEEEEEETTEEEEEEEE~TTSGGG~B~HHHHHHHHHHHHHHHHHT~~EEEEE~~~SB~GGGTHHHHHHHHHHHHHHHHHTTTS~EEEEE~SEEEGGGGHHHHHSSEEEEETTT~EEESS~HHHHHHHH~~~~~HHHHHBHHHHHHTS~~~SEEESSHHHHHHHHHHHHHTS~SSTTS~~~~~~~~~~~S~~HHHHHHHHHS~SSTT~~~~HHHHHHTTSGGG~~EEE~SSS~TTEEEEEEEETTEEEEEEEE~TTTGGG~B~HHHHHHHHHHHHHHHHTT~~EEEEEEE~~B~~~HHHHHTTHHHHTHHHHHHHHH~~S~EEEEEEEEEEHHHHHHTT~GGGT~SEEEE~TT~EEESS~HHHHHHHHTHHHHHSS~TT~TTTHHHHHHHHHHHHSSSHHHHHTTSSSEE~~GGGHHHHHHHHHHHHTT~~~~~~~~S~~~~~~~~SSHHHHHHHHHHHHHHHHT~S~HHHHHHHHHTT~~~HHHHHHHHS~TT~~EEESTT~~~~~~GGGGGG~~~TTTTEEEEEEEETTEEEEEEEE~TTSGGG~B~HHHHHHHHHHHHHHHHHT~~EEEEEEE~SB~GGGTHHHHHHHHHHHHHHHHTTTTS~EEEEEEEEEEGGGGHHHHHSSEEEEETTT~EEESS~HHHHHHHH~~~~~HHHHHBHHHHHHTS~~~SEEESSHHHHHHHHHHHHHHS~SSTTS~~~~~~~~~~~S~~HHHHHHHHHS~SSTTS~~~HHHHHHTTSGGG~~EEESTTS~TTEEEEEEEETTEEEEEEEE~TTTGGG~B~HHHHHHHHHHHHHHHHTT~~EEEEEEE~~B~~~HHHHHTTHHHHTHHHHHHHHH~~S~EEEEEEEEEEHHHHHHTT~GGGT~SEEEE~TT~EEESS~HHHHHHHHTHHHHHS~~SS~TTHHHHHHHHHHHHHSSSHHHHHHTSSSEE~~GGGHHHHHHHHHHHHTT~~~~~~~~S~~~~~~

D I H T T A G K L A D L R R R I E E A T H A G S A R A V E K Q H A K G K L T A R E R I D L L L D E G S F V E L D E F A R H R S T N F G L D A N R P Y G D G V V T G Y G T V D G R P V A V F S Q D F T V F G G A L G E V Y G Q K I V K V M D F A L K T G C P V V G I N D S G G A R I Q E G V A S L G A Y G E I F R R N T H A S G V I P Q I S L V V G P C A G G A V Y S P A I T D F T V M V D Q T S H M F I T G P D V I K T V T G E D V G F E E L G G A R T H N S T S G V A H H M A G D E K D A V E Y V K Q L L S Y L P S N N L S E P P A F P E E A D L A V T D E D A E L D T I V P D S A N Q P Y D M H S V I E H V L D D A E F F E T Q P L F A P N I L T G F G R V E G R P V G I V A N Q P M Q F A G C L D I T A S E K A A R F V R T C D A F N V P V L T F V D V P G F L P G V D Q E H D G I I R R G A K L I F A Y A E A T V P L I T V I T R K A F G G A Y D V M G S K H L G A D L N L A W P T A Q I A V M G A Q G A V N I L H R R T I A D A G D D A E A T R A R L I Q E Y E D A L L N P Y T A A E R G Y V D A V I M P S D T R R H I V R G L R Q L R T K R E S L P P K K H G N I P L D I H T T A G K L A D L R R R I E E A T H A G S A R A V E K Q H A K G K L T A R E R I D L L L D E G S F V E L D E F A R H R S T N F G L D A N R P Y G D G V V T G Y G T V D G R P V A V F S Q D F T V F G G A L G E V Y G Q K I V K V M D F A L K T G C P V V G I N D S G G A R I Q E G V A S L G A Y G E I F R R N T H A S G V I P Q I S L V V G P C A G G A V Y S P A I T D F T V M V D Q T S H M F I T G P D V I K T V T G E D V G F E E L G G A R T H N S T S G V A H H M A G D E K D A V E Y V K Q L L S Y L P S N N L S E P P A F P E E A D L A V T D E D A E L D T I V P D S A N Q P Y D M H S V I E H V L D D A E F F E T Q P L F A P N I L T G F G R V E G R P V G I V A N Q P M Q F A G C L D I T A S E K A A R F V R T C D A F N V P V L T F V D V P G F L P G V D Q E H D G I I R R G A K L I F A Y A E A T V P L I T V I T R K A F G G A Y D V M G S K H L G A D L N L A W P T A Q I A V M G A Q G A V N I L H R R T I A D A G D D A E A T R A R L I Q E Y E D A L L N P Y T A A E R G Y V D A V I M P S D T R R H I V R G L R Q L R T K R E S L P P K K H G N I P L D I H T T A G K L A D L R R R I E E A T H A G S A R A V E K Q H A K G K L T A R E R I D L L L D E G S F V E L D E F A R H R S T N F G L D A N R P Y G D G V V T G Y G T V D G R P V A V F S Q D F T V F G G A L G E V Y G Q K I V K V M D F A L K T G C P V V G I N D S G G A R I Q E G V A S L G A Y G E I F R R N T H A S G V I P Q I S L V V G P C A G G A V Y S P A I T D F T V M V D Q T S H M F I T G P D V I K T V T G E D V G F E E L G G A R T H N S T S G V A H H M A G D E K D A V E Y V K Q L L S Y L P S N N L S E P P A F P E E A D L A V T D E D A E L D T I V P D S A N Q P Y D M H S V I E H V L D D A E F F E T Q P L F A P N I L T G F G R V E G R P V G I V A N Q P M Q F A G C L D I T A S E K A A R F V R T C D A F N V P V L T F V D V P G F L P G V D Q E H D G I I R R G A K L I F A Y A E A T V P L I T V I T R K A F G G A Y D V M G S K H L G A D L N L A W P T A Q I A V M G A Q G A V N I L H R R T I A D A G D D A E A T R A R L I Q E Y E D A L L N P Y T A A E R G Y V D A V I M P S D T R R H I V R G L R Q L R T K R E S L P P K K H G N I P L D I H T T A G K L A D L R R R I E E A T H A G S A R A V E K Q H A K G K L T A R E R I D L L L D E G S F V E L D E F A R H R S T N F G L D A N R P Y G D G V V T G Y G T V D G R P V A V F S Q D F T V F G G A L G E V Y G Q K I V K V M D F A L K T G C P V V G I N D S G G A R I Q E G V A S L G A Y G E I F R R N T H A S G V I P Q I S L V V G P C A G G A V Y S P A I T D F T V M V D Q T S H M F I T G P D V I K T V T G E D V G F E E L G G A R T H N S T S G V A H H M A G D E K D A V E Y V K Q L L S Y L P S N N L S E P P A F P E E A D L A V T D E D A E L D T I V P D S A N Q P Y D M H S V I E H V L D D A E F F E T Q P L F A P N I L T G F G R V E G R P V G I V A N Q P M Q F A G C L D I T A S E K A A R F V R T C D A F N V P V L T F V D V P G F L P G V D Q E H D G I I R R G A K L I F A Y A E A T V P L I T V I T R K A F G G A Y D V M G S K H L G A D L N L A W P T A Q I A V M G A Q G A V N I L H R R T I A D A G D D A E A T R A R L I Q E Y E D A L L N P Y T A A E R G Y V D A V I M P S D T R R H I V R G L R Q L R T K R E S L P P K K H G N I P L D I H T T A G K L A D L R R R I E E A T H A G S A R A V E K Q H A K G K L T A R E R I D L L L D E G S F V E L D E F A R H R S T N F G L D A N R P Y G D G V V T G Y G T V D G R P V A V F S Q D F T V F G G A L G E V Y G Q K I V K V M D F A L K T G C P V V G I N D S G G A R I Q E G V A S L G A Y G E I F R R N T H A S G V I P Q I S L V V G P C A G G A V Y S P A I T D F T V M V D Q T S H M F I T G P D V I K T V T G E D V G F E E L G G A R T H N S T S G V A H H M A G D E K D A V E Y V K Q L L S Y L P S N N L S E P P A F P E E A D L A V T D E D A E L D T I V P D S A N Q P Y D M H S V I E H V L D D A E F F E T Q P L F A P N I L T G F G R V E G R P V G I V A N Q P M Q F A G C L D I T A S E K A A R F V R T C D A F N V P V L T F V D V P G F L P G V D Q E H D G I I R R G A K L I F A Y A E A T V P L I T V I T R K A F G G A Y D V M G S K H L G A D L N L A W P T A Q I A V M G A Q G A V N I L H R R T I A D A G D D A E A T R A R L I Q E Y E D A L L N P Y T A A E R G Y V D A V I M P S D T R R H I V R G L R Q L R T K R E S L P P K K H G N I P L D I H T T A G K L A D L R R R I E E A T H A G S A R A V E K Q H A K G K L T A R E R I D L L L D E G S F V E L D E F A R H R S T N F G L D A N R P Y G D G V V T G Y G T V D G R P V A V F S Q D F T V F G G A L G E V Y G Q K I V K V M D F A L K T G C P V V G I N D S G G A R I Q E G V A S L G A Y G E I F R R N T H A S G V I P Q I S L V V G P C A G G A V Y S P A I T D F T V M V D Q T S H M F I T G P D V I K T V T G E D V G F E E L G G A R T H N S T S G V A H H M A G D E K D A V E Y V K Q L L S Y L P S N N L S E P P A F P E E A D L A V T D E D A E L D T I V P D S A N Q P Y D M H S V I E H V L D D A E F F E T Q P L F A P N I L T G F G R V E G R P V G I V A N Q P M Q F A G C L D I T A S E K A A R F V R T C D A F N V P V L T F V D V P G F L P G V D Q E H D G I I R R G A K L I F A Y A E A T V P L I T V I T R K A F G G A Y D V M G S K H L G A D L N L A W P T A Q I A V M G A Q G A V N I L H R R T I A D A G D D A E A T R A R L I Q E Y E D A L L N P Y T A A E R G Y V D A V I M P S D T R R H I V R G L R Q L R T K R E S L P P K K H G N I P L

AH

UNSTRUCTURED

5MMF

GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVGPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV

~~~~~~~SSSTTTTTTS~HHHH~TTS~~~~~EEGGGEEEEEEEEE~SSEEEEEEEETTTTEEEEEEEE~~S~HHHHHHHHHHHHHHTT~TTB~~EEEEEE~TTT~~EEEEEE~~~~~~HHHHHHH~~HHHHHHHHHHHHHHHHHHHHTTEE~~~~SGGGEEEETTTTEEEE~~~TT~EE~~TT~~~~S~~S~GGG~~HHHHTT~~~~~THHHHHHHHHHHHHHHHT~SSSS~~SSHHHHHHHHHHHH~HHHHHHHHHHTT~~~~GGGTTT~~~~~~~~GGGG~~TTTGGG~~HHHHHHHHHHS~SSGGGS~~HHHHHTSGGGTT~~~~~~~~~SSSTTTTTTS~HHHH~GGG~~~~~EEGGGEEEEEEEEE~SSEEEEEEEETTTTEEEEEEEE~~S~HHHHHHHHHHHHHHTT~TTB~~EEEEEE~TTT~~EEEEEE~~~~~~TTHHHHS~~HHHHHHHHHHHHHHHHHHHHTTEE~~~~SGGGEEEETTTTEEEE~~~TT~EE~~TT~~~~S~~S~GGG~~HHHHTT~~~~~THHHHHHHHHHHHHHHTT~SSSS~~SSHHHHHHHHHHHH~HHHHHHHHHHTT~~~~GGGTTT~~~~~~~~GGGG~~TTTGGG~~HHHHHHHHHHS~SSGGGS~~HHHHHHSGGGTT~

G P V P S R A R V Y T D V N T H R P S E Y W D Y E S H V V E W G N Q D D Y Q L V R K L G R G K Y S E V F E A I N I T N N E K V V V K I L K P V K K K K I K R E I K I L E N L R G G P N I I T L A D I V K D P V S R T P A L V F E H V N N T D F K Q L Y Q T L T D Y D I R F Y M Y E I L K A L D Y C H S M G I M H R D V K P H N V M I D H E H R K L R L I D W G L A E F Y H P G Q E Y N V R V A S R Y F K G P E L L V D Y Q M Y D Y S L D M W S L G C M L A S M I F R K E P F F H G H D N Y D Q L V R I A K V L G T E D L Y D Y I D K Y N I E L D P R F N D I L G R H S R K R W E R F V H S E N Q H L V S P E A L D F L D K L L R Y D H Q S R L T A R E A M E H P Y F Y T V V G P V P S R A R V Y T D V N T H R P S E Y W D Y E S H V V E W G N Q D D Y Q L V R K L G R G K Y S E V F E A I N I T N N E K V V V K I L K P V K K K K I K R E I K I L E N L R G G P N I I T L A D I V K D P V S R T P A L V F E H V N N T D F K Q L Y Q T L T D Y D I R F Y M Y E I L K A L D Y C H S M G I M H R D V K P H N V M I D H E H R K L R L I D W G L A E F Y H P G Q E Y N V R V A S R Y F K G P E L L V D Y Q M Y D Y S L D M W S L G C M L A S M I F R K E P F F H G H D N Y D Q L V R I A K V L G T E D L Y D Y I D K Y N I E L D P R F N D I L G R H S R K R W E R F V H S E N Q H L V S P E A L D F L D K L L R Y D H Q S R L T A R E A M E H P Y F Y T V

AH

UNSTRUCTURED

4L5E

HKSIKEIEKEEIIKVLKEVNFNKKLASEILGIPLRTLYKRLKEYGI

~~~HHHHHHHHHHHHHHHTTT~HHHHHHHHES~HHHHHHHHHHHT~

H K S I K E I E K E E I I K V L K E V N F N K K L A S E I L G I P L R T L Y K R L K E Y G I

AH

UNSTRUCTURED

4IQ7

ATVLLEVPFSARGDRIPDAVAELRTREPIRKVRTITGAEAWLVSSYALCTQVLEDRRFSMKETAAAGAPRLNALTVPPEVVNNMGNIADAGLRKAVMKAITPKAPGLEQFLRDTANSLLDNLITEGAPADLRNDFADPLATALHCKVLGIPQEDGPKLFRSLSIAFMSSADPIPAAKINWDRDIEYMAGILENPNITTGLMGELSRLRKDPAYSHVSDELFATIGVTFFGAGVISTGSFLTTALISLIQRPQLRNLLHEKPELIPAGVEELLRINLSFADGLPRLATADIQVGDVLVRKGELVLVLLEGANFDPEHFPNPGSIELDRPNPTSHLAFGRGQHFCPGSALGRRHAQIGIEALLKKMPGVDLAVPIDQLVWRTRFQRRIPERLPVLW

~~~~~BS~~~~~SSS~~THHHHHHHH~SEEEEE~TTS~EEEEE~SHHHHHHHHT~TTEESGGGGSTT~~~SS~~SS~GGGGGHHHHHHHTT~HHHHHHHT~TTSTTHHHHHHHHHHHHHHHHHHH~S~EETTTTTHHHHHHHHHHHHHT~~GGGHHHHHHTHHHHTB~~SS~~HHHHHHHHHHHHHHHHHHH~TT~~SHHHHHHHHHHTSGGGTTS~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT~HHHHHHHHH~GGGHHHHHHHHHHT~~~B~S~EEEEESS~EEETTEEE~TT~EEEE~HHHHHT~TTTSSSTTS~~TT~SSTT~S~TT~~GGG~~TTHHHHHHHHHHHHHHHHHH~TT~EESS~GGG~~B~~SBSB~~BS~~EEE~

A T V L L E V P F S A R G D R I P D A V A E L R T R E P I R K V R T I T G A E A W L V S S Y A L C T Q V L E D R R F S M K E T A A A G A P R L N A L T V P P E V V N N M G N I A D A G L R K A V M K A I T P K A P G L E Q F L R D T A N S L L D N L I T E G A P A D L R N D F A D P L A T A L H C K V L G I P Q E D G P K L F R S L S I A F M S S A D P I P A A K I N W D R D I E Y M A G I L E N P N I T T G L M G E L S R L R K D P A Y S H V S D E L F A T I G V T F F G A G V I S T G S F L T T A L I S L I Q R P Q L R N L L H E K P E L I P A G V E E L L R I N L S F A D G L P R L A T A D I Q V G D V L V R K G E L V L V L L E G A N F D P E H F P N P G S I E L D R P N P T S H L A F G R G Q H F C P G S A L G R R H A Q I G I E A L L K K M P G V D L A V P I D Q L V W R T R F Q R R I P E R L P V L W

AH

UNSTRUCTURED

3JYZ

GIDPFTVRTRVSEGLVLAEPAKLISTDGSASTADLTRATTTWNQQSNNLGASSKYVTSVLDAGNTGVITITYVADQVGLPTAGNTLILSPYINDGNTRTALATAVAAGTRGTIDWACTSASNATATAQGFTGAAGSVPQEFAPAQCR

~~~HHHHHHHHHHHHHHHHHHH~~TTTSSSSHHHHHHHHHHHHHHHHHTS~~~SSEEEE~~TTS~~~EEEEE~HHHHT~~TT~~EEEEEEEEE~SS~EEEHHHHHHHT~~~EEEEEEESS~~HHHHHTT~~~~~~~S~GGGS~GGG~

G I D P F T V R T R V S E G L V L A E P A K L I S T D G S A S T A D L T R A T T T W N Q Q S N N L G A S S K Y V T S V L D A G N T G V I T I T Y V A D Q V G L P T A G N T L I L S P Y I N D G N T R T A L A T A V A A G T R G T I D W A C T S A S N A T A T A Q G F T G A A G S V P Q E F A P A Q C R

AH

UNSTRUCTURED

2KNM

GIPCGESCVWIPCISSAIGCSCKSKVCYRN

~EEEEEETTTSH~GGGGGT~EEETTEEEE~

G I P C G E S C V W I P C I S S A I G C S C K S K V C Y R N

BS

T

3D93

HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK

~~~SSTTTSGGGHHHH~GGGGSSS~S~~EE~TTT~EE~TT~~~EEEE~TT~~EEEEEE~SSSEEEEE~~SSSSSEEEETT~~S~EEEEEEEEEE~SSTT~~~SSEETTB~~SEEEEEEEEEGGGSSHHHHTTSTTSEEEEEEEEEESS~~GGGHHHHHHGGGG~STT~EEE~~S~~GGGG~~S~~~EEEEEE~~SSTT~~S~EEEEEESS~EEE~HHHHHHHTT~BSS~TTS~~~B~~~~~~~~~~~~S~~~EES~~

H W G Y G K H N G P E H W H K D F P I A K G E R Q S P V D I D T H T A K Y D P S L K P L S V S Y D Q A T S L R I L N N G H A F N V E F D D S Q D K A V L K G G P L D G T Y R L I Q F H F H W G S L D G Q G S E H T V D K K K Y A A E L H L V H W N T K Y G D F G K A V Q Q P D G L A V L G I F L K V G S A K P G L Q K V V D V L D S I K T K G K S A D F T N F D P R G L L P E S L D Y W T Y P G S L T T P P L L E C V T W I V L K E P I S V S S E Q V L K F R K L N F N G E G E P E E L M V D N W R P A Q P L K N R Q I K A S F K

BS

UNSTRUCTURED

5P1J

STGSATTTPIDSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDGQTIYTPSKSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQAVESAKKVSSSFTEDSTIDGLLGLAFSTLNTVSPTQQKTFFDNAKASLDSPVFTADLGYHAPGTYNFGFIDTTAYTGSITYTAVSTKQGFWEWTSTGYAVGSGTFKSTSIDGIADTGTTLLYLPATVVSAYWAQVSGAKSSSSVGGYVFPCSATLPSFTFGVGSARIVIPGDYIDFGPISTGSSSCFGGIQSSAGIGINIFGDVALKAAFVVFNGATTPTLGFASK

~~EEEEEEESSTT~~~EEEEEEETTTTEEEEEEEETT~~~EEE~BTTS~GGG~SS~~~B~GGG~TT~EEEEEEEEEEE~TTS~EEEEEEEEEEEEETTEEEEEEEEEEEEEE~HHHHT~TT~~EEEE~S~GGG~~~BSS~~~~HHHHHGGGSSSSEEEEE~~SSS~EEEEES~~~TTSSSS~~EEEE~B~TTSS~EEEEEEEEETTS~~EEEEEEEEE~TT~~SEEE~HHHHHHHHTTSTT~EEETTTTEEEEETT~~~~~EEEEETTEEEEE~GGGGEEEESSTT~SEEEESEEE~TTTSSEEE~HHHHTTSEEEEE~SSS~EEEEE~~

S T G S A T T T P I D S L D D A Y I T P V Q I G T P A Q T L N L D F D T G S S D L W V F S S E T T A S E V D G Q T I Y T P S K S T T A K L L S G A T W S I S Y G D G S S S S G D V Y T D T V S V G G L T V T G Q A V E S A K K V S S S F T E D S T I D G L L G L A F S T L N T V S P T Q Q K T F F D N A K A S L D S P V F T A D L G Y H A P G T Y N F G F I D T T A Y T G S I T Y T A V S T K Q G F W E W T S T G Y A V G S G T F K S T S I D G I A D T G T T L L Y L P A T V V S A Y W A Q V S G A K S S S S V G G Y V F P C S A T L P S F T F G V G S A R I V I P G D Y I D F G P I S T G S S S C F G G I Q S S A G I G I N I F G D V A L K A A F V V F N G A T T P T L G F A S K

BS

UNSTRUCTURED

2KUX

GTPCGESCVYIPCISGVIGCSCTDKVCYLN

~EEEEEE~SHS~~SGGGGS~EEETTEEEE~

G T P C G E S C V Y I P C I S G V I G C S C T D K V C Y L N

BS

UNSTRUCTURED

2Y27

LEPIETASRDELTALQLERLKWSLRHAYDHSPVYRRKFDEAGVHPDDLKTLADLSRFPFTTKGDLRDSYPFGFAVPQDRISRIHASSGTTGKPTVVGYTAADIDTWANLVARSIRAAGARRGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIPFGGGQTEKQVQLIQDFRPDIIVTPSYLSIADEIERQGLDPVQSSLRIGIFGAEPWTNDRVAIEQRGIDAVDIYGLSEVGPGVASECVETKDGPTIWEDHFYPEIIDPETGEVLPDGELGELVFTSLTKEALPIIRYRTRDLTRLLPGTARTRREKITGRSDDIVRGVNVFPTQIEEQLLKQRALAPHYQIVLTKEGPLDVLTLNVEPCPETAPDTAAIQVAKQALAYDIKSLIGVTAVINVLPVNGIERSVGKARRVVDKRKPLPLEPIETASRDELTALQLERLKWSLRHAYDHSPVYRRKFDEAGVHPDDLKTLADLSRFPFTTKGDLRDSYPFGFAVPQDRISRIHASSGTTGKPTVVGYTAADIDTWANLVARSIRAAGARRGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIPFGGGQTEKQVQLIQDFRPDIIVTPSYLSIADEIERQGLDPVQSSLRIGIFGAEPWTNDRVAIEQRGIDAVDIYGLSEVGPGVASECVETKDGPTIWEDHFYPEIIDPETGEVLPDGELGELVFTSLTKEALPIIRYRTRDLTRLLPGTARTRREKITGRSDDIVRGVNVFPTQIEEQLLKQRALAPHYQIVLTKEGPLDVLTLNVEPCPETAPDTAAIQVAKQALAYDIKSLIGVTAVINVLPVNGIERSVGKARRVVDKR

~~GGGG~~HHHHHHHHHHHHHHHHHHHHHH~HHHHHHHHHHT~~GGG~SSGGGGGGS~~B~HHHHHHTTTT~~~S~GGG~~EEEE~~~TTSS~~EEEE~HHHHHHHHHHHHHHHHHTT~~TT~EEE~~S~~SSSHHHHHHHHHHHHTT~EEE~~~S~~HHHHHHHHHHH~~SB~~~S~~~HHHHHHHHTT~~GGGSS~~EEEEESS~~~~~~HHHHH~~~EEEEEEE~TT~~EEEEE~~TTT~SS~EE~TTTEEEEEE~TTT~~B~~TT~~EEEEEEESS~SSS~~~SEEEEEEE~~~~~SS~~~~~~~~EETT~~BTTB~~~HHHHHHHHTT~TTB~S~~EEEEEEETTEEEEEEEE~B~TTTTT~HHHHHHHHHHHHHHHHHHH~~~EEEEE~~TT~S~~~SSS~~~EEE~~~~~~~~GGGGS~HHHHHHHHHHHHHHHHHHHHHH~HHHHHHHHHTT~~GGG~SSGGGGGGS~~B~HHHHHHTTTT~~~S~GGG~~EEEE~~~SSSS~~EEEE~HHHHHHHHHHHHHHHHHTT~~TT~EEEE~S~~SSSHHHHHHHHHHHHTT~EEEE~~S~~HHHHHHHHHHH~~SB~~~S~~~HHHHHHHHTT~~GGGSS~~EEEEESS~~~~~~HHHHH~~~EEEEEEE~TT~~EEEEE~~TTT~SS~EE~TTTEEEEEE~TTT~~B~~TTS~EEEEEEESS~SSS~~~SEEEEEEE~~~~~SS~~~~~~~~EETT~~BTTB~~~HHHHHHHHTT~TTB~S~~EEEEEEETTEEEEEEEE~B~GGGTT~HHHHHHHHHHHHHHHHHHH~~~EEEEE~~TT~S~~~SSS~~~EEE~~

L E P I E T A S R D E L T A L Q L E R L K W S L R H A Y D H S P V Y R R K F D E A G V H P D D L K T L A D L S R F P F T T K G D L R D S Y P F G F A V P Q D R I S R I H A S S G T T G K P T V V G Y T A A D I D T W A N L V A R S I R A A G A R R G D K V H V S Y G Y G L F T G G L G A H Y G A E R A G L T V I P F G G G Q T E K Q V Q L I Q D F R P D I I V T P S Y L S I A D E I E R Q G L D P V Q S S L R I G I F G A E P W T N D R V A I E Q R G I D A V D I Y G L S E V G P G V A S E C V E T K D G P T I W E D H F Y P E I I D P E T G E V L P D G E L G E L V F T S L T K E A L P I I R Y R T R D L T R L L P G T A R T R R E K I T G R S D D I V R G V N V F P T Q I E E Q L L K Q R A L A P H Y Q I V L T K E G P L D V L T L N V E P C P E T A P D T A A I Q V A K Q A L A Y D I K S L I G V T A V I N V L P V N G I E R S V G K A R R V V D K R K P L P L E P I E T A S R D E L T A L Q L E R L K W S L R H A Y D H S P V Y R R K F D E A G V H P D D L K T L A D L S R F P F T T K G D L R D S Y P F G F A V P Q D R I S R I H A S S G T T G K P T V V G Y T A A D I D T W A N L V A R S I R A A G A R R G D K V H V S Y G Y G L F T G G L G A H Y G A E R A G L T V I P F G G G Q T E K Q V Q L I Q D F R P D I I V T P S Y L S I A D E I E R Q G L D P V Q S S L R I G I F G A E P W T N D R V A I E Q R G I D A V D I Y G L S E V G P G V A S E C V E T K D G P T I W E D H F Y P E I I D P E T G E V L P D G E L G E L V F T S L T K E A L P I I R Y R T R D L T R L L P G T A R T R R E K I T G R S D D I V R G V N V F P T Q I E E Q L L K Q R A L A P H Y Q I V L T K E G P L D V L T L N V E P C P E T A P D T A A I Q V A K Q A L A Y D I K S L I G V T A V I N V L P V N G I E R S V G K A R R V V D K R

AH

UNSTRUCTURED

5T7A

NGDSHTHPDYTAGIRGITGNEVTIFFAPTTEARYVDVHLKVNNGQQLNYRMTERNGEWERVVENLSSGDVLEYSFTYEKLGPQYTTEWFTYSRGDSHTHPDYTAGIRGITGNEVTIFFAPTTEARYVDVHLKVNNGQQLNYRMTERNGEWERVVENLSSGDVLEYSFTYEKLGPQYTTEWFTYSR

~~EEEEETTEEEEEE~~~SSEEEEEEEESS~~S~EEEEEEETT~~~EEEE~EEETTEEEEEEE~~~TT~EEEEEEEEE~SSSEEE~~~EEEE~~~EEEETTEEEEEE~~~SSEEEEEEEESS~~S~EEEEEEETT~~~EEEE~EEETTEEEEEEE~~~TT~EEEEEEEEE~SSSEEH~~~EEEE~

N G D S H T H P D Y T A G I R G I T G N E V T I F F A P T T E A R Y V D V H L K V N N G Q Q L N Y R M T E R N G E W E R V V E N L S S G D V L E Y S F T Y E K L G P Q Y T T E W F T Y S R G D S H T H P D Y T A G I R G I T G N E V T I F F A P T T E A R Y V D V H L K V N N G Q Q L N Y R M T E R N G E W E R V V E N L S S G D V L E Y S F T Y E K L G P Q Y T T E W F T Y S R

BS

UNSTRUCTURED

2ONI

LYFQGSREFKQKYDYFRKKLKKPADIPNRFEKLHRNNIFEESYRRISVKRPDVLKARLWIEFEEKGLDYGGVAREWFFLLSKEFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYKLGKQITLNDESVDSEYYNSLKWILENDPTELDLFCIDEENFGQTYQVDLKPNGSEIVTNENKREYIDLVIQWRFVNRVQKQNAFLEGFTELLPIDLIKIFDENELELLCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLDAEKRIRLLQFVTGTSRVPNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTCFNRLDLPPYETFEDLREKLLAVE

~~STTHHHHHHHHHHHHHH~~~~SSS~SEE~~B~GGGHHHHHHHH~~~S~GGGGGSEE~~~B~~~SS~HHHHHHHHHHHHHH~~~GGGSSEEESSTT~~~EEE~TTHHHH~TTHHHHHHHHHHHHHHHHHHT~~~SS~B~HHHH~~~~~~~TT~~~S~HHHHHHHHHHHHS~~GGG~~~EEEEEETTEEEEEESSTTGGG~~~TTTHHHHHHHHHHHHHTTTSS~~~HHHHHHHHHS~HHHHTTS~HHHHHH~~~~~~~~HHHHHHT~EEETT~~TT~HHHHHHHHHHH~~HHHHHHHHHHHHS~S~~~~~GGG~EETTEE~~~EEEE~S~TTS~~EEEGGGTEEEE~~~SSHHHHHHHH~~~~

L Y F Q G S R E F K Q K Y D Y F R K K L K K P A D I P N R F E K L H R N N I F E E S Y R R I S V K R P D V L K A R L W I E F E E K G L D Y G G V A R E W F F L L S K E F N P Y Y G L F E Y S A T D N Y T L Q I N P N S G L C N E D H L S Y F T F I G R V A G L A V F H G K L L D G F F I R P F Y K L G K Q I T L N D E S V D S E Y Y N S L K W I L E N D P T E L D L F C I D E E N F G Q T Y Q V D L K P N G S E I V T N E N K R E Y I D L V I Q W R F V N R V Q K Q N A F L E G F T E L L P I D L I K I F D E N E L E L L C G L G D V D V N D W R Q H S I Y K N G Y C P N H P V I Q W F W K A V L L D A E K R I R L L Q F V T G T S R V P N G F A E L Y G S N G P Q L F T I E Q W G S P E K L P R A H T C F N R L D L P P Y E T F E D L R E K L L A V E

AH

UNSTRUCTURED

2HXO

LSRERIVGAAVELLDTVGERGLTFRALAERLATGPGAIYWHITGKAELLGAATDAVVTAAVTAGPTGAADSPQDAVRAVALGLWDATEAHPWLATQLATQLSRTPWGTVAPRIFESLGRQVQAGVPEAHWFTASSALHYILGAAGQNAANDEFLDTVSTAWEGLDPDAYPFTRAVADQVRGHDDREQFLAGITLVLTGITALHRPPLSRERIVGAAVELLDTVGERGLTFRALAERLATGPGAIYWHITGKAELLGAATDAVVTAAVTAAADSPQDAVRAVALGLWDATEAHPWLATQLATQLSRTPWGTVAPRIFESLGRQVQAGVPEAHWFTASSALHYILGAAGQNAANSADRDEFLDTVSTAWEGLDPDAYPFTRAVADQVRGHDDREQFLAGITLVLTGITALHR

~~HHHHHHHHHHHHHHTTTTT~~HHHHHHHHTS~GGGGGGT~~~HHHHHHHHHHHHHHHHHT~S~~~TT~~HHHHHHHHHHHHHHHHHH~THHHHHHHHHHHH~TT~SHHHHHHHHHHHHHHEE~~GGGHHHHHHH~~HHHHHHHHHHH~~HHHHHHHHHHTTS~TTT~HHHHHHGGGGTT~~HHHHHHHHHHHHHHHHHTT~~~~~~HHHHHHHHHHHHHHTTTTT~~HHHHHHHHTS~GGGGGGT~~~HHHHHHHHHHHHHHHHHH~~~S~HHHHHHHHHHHHHHHHHH~THHHHHHHHHHHH~TT~SHHHHHHHHHHHHHH~~~~GGGHHHHHHH~~HHHHHHHHHHHHT~~HHHHHHHHHHHHHTS~TTT~HHHHHHHHHHTT~~HHHHHHHHHHHHHHHHHTT~~

L S R E R I V G A A V E L L D T V G E R G L T F R A L A E R L A T G P G A I Y W H I T G K A E L L G A A T D A V V T A A V T A G P T G A A D S P Q D A V R A V A L G L W D A T E A H P W L A T Q L A T Q L S R T P W G T V A P R I F E S L G R Q V Q A G V P E A H W F T A S S A L H Y I L G A A G Q N A A N D E F L D T V S T A W E G L D P D A Y P F T R A V A D Q V R G H D D R E Q F L A G I T L V L T G I T A L H R P P L S R E R I V G A A V E L L D T V G E R G L T F R A L A E R L A T G P G A I Y W H I T G K A E L L G A A T D A V V T A A V T A A A D S P Q D A V R A V A L G L W D A T E A H P W L A T Q L A T Q L S R T P W G T V A P R I F E S L G R Q V Q A G V P E A H W F T A S S A L H Y I L G A A G Q N A A N S A D R D E F L D T V S T A W E G L D P D A Y P F T R A V A D Q V R G H D D R E Q F L A G I T L V L T G I T A L H R

AH

UNSTRUCTURED

1AU2

APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM

~~S~EEHHHHT~~~~~~B~~SS~~HHHHHHHHHHHHHHHHTTS~~~~B~HHHHHHH~TTS~GGG~~~SHHHHHHHHHHT~EEBTTTS~~~SS~~~~~~~GGGEEE~~S~EEE~~TT~HHHHHHHHHHH~~EEEEE~~~SHHHHT~~SSEE~~TT~~TT~~~EEEEE~EEEESSS~EEEEEE~SB~TTSTBTTEEEEESSSSSGGGTTSS~EEE~~

A P D S V D Y R K K G Y V T P V K N Q G Q C G S C W A F S S V G A L E G Q L K K K T G K L L N L S P Q N L V D C V S E N D G C G G G Y M T N A F Q Y V Q K N R G I D S E D A Y P Y V G Q E E S C M Y N P T G K A A K C R G Y R E I P E G N E K A L K R A V A R V G P V S V A I D A S L T S F Q F Y S K G V Y Y D E S C N S D N L N H A V L A V G Y G I Q K G N K H W I I K N S W G E N W G N K G Y I L M A R N K N N A C G I A N L A S F P K M

UNSTRUCTURED

AH

1QG6

GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNEGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNEGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNEGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNE

~TTTT~EEEE~~~~STT~HHHHHHHHHHHTT~EEEEEESSHHHHHHHHHHHHHTT~~~EEE~~TT~HHHHHHHHHHHTTT~SSB~~EEE~~~~~~GGGGSS~HHHH~~HHHHHHHHHHHTHHHHHHHHHHGGGB~TTEEEEEEE~GGGTSB~TTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE~~~~~TGGGGSTTHHHHHHHHHHHSTTSS~~~HHHHHHHHHHHHSGGGTT~~S~EEEESTTGGGB~~~~~TTTT~EEEE~~~~STT~HHHHHHHHHHHTT~EEEEEESSHHHHHHHHHHHHHTT~~~EEE~~TT~HHHHHHHHHHHTTT~SSB~~EEE~~~~~~GGGGSS~HHHH~~HHHHHHHHHHHTHHHHHHHHHHGGGB~TTEEEEEEE~GGGTSB~TTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE~~~~~TGGGGSTTHHHHHHHHHHHSTTSS~~~HHHHHHHHHHHHSGGGTT~~S~EEEESTTGGGB~~~~~TTTT~EEEE~~~~STT~HHHHHHHHHHHTT~EEEEEESSHHHHHHHHHHHHHTT~~~EEE~~TT~HHHHHHHHHHHTTT~SSB~~EEE~~~~~~GGGGSS~HHHH~~HHHHHHHHHHHTHHHHHHHHHHGGGB~TTEEEEEEE~GGGTSB~TTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE~~~~~TGGGGSTTHHHHHHHHHHHSTTSS~~~HHHHHHHHHHHHSGGGTT~~S~EEEESTTGGGB~~~~~TTTT~EEEE~~~~STT~HHHHHHHHHHHTT~EEEEEESSHHHHHHHHHHHHHTT~~~EEE~~TT~HHHHHHHHHHHTTT~SSB~~EEE~~~~~~GGGGSS~HHHH~~HHHHHHHHHHHTHHHHHHHHHHGGGB~TTEEEEEEE~GGGTSB~TTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE~~~~~TGGGGSTTHHHHHHHHHHHSTTSS~~~HHHHHHHHHHHHSGGGTT~~S~EEEESTTGGGB~~~~

G F L S G K R I L V T G V A S K L S I A Y G I A Q A M H R E G A E L A F T Y Q N D K L K G R V E E F A A Q L G S D I V L Q C D V A E D A S I D T M F A E L G K V W P K F D G F V H S I G F A P G D Q L D G D Y V N A V T R E G F K I A H D I S S Y S F V A M A K A C R S M L N P G S A L L T L S Y L G A E R A I P N Y N V M G L A K A S L E A N V R Y M A N A M G P E G V R V N A I S A G P I R T L A A S G I K D F R K M L A H C E A V T P I R R T V T I E D V G N S A A F L C S D L S A G I S G E V V H V D G G F S I A A M N E G F L S G K R I L V T G V A S K L S I A Y G I A Q A M H R E G A E L A F T Y Q N D K L K G R V E E F A A Q L G S D I V L Q C D V A E D A S I D T M F A E L G K V W P K F D G F V H S I G F A P G D Q L D G D Y V N A V T R E G F K I A H D I S S Y S F V A M A K A C R S M L N P G S A L L T L S Y L G A E R A I P N Y N V M G L A K A S L E A N V R Y M A N A M G P E G V R V N A I S A G P I R T L A A S G I K D F R K M L A H C E A V T P I R R T V T I E D V G N S A A F L C S D L S A G I S G E V V H V D G G F S I A A M N E G F L S G K R I L V T G V A S K L S I A Y G I A Q A M H R E G A E L A F T Y Q N D K L K G R V E E F A A Q L G S D I V L Q C D V A E D A S I D T M F A E L G K V W P K F D G F V H S I G F A P G D Q L D G D Y V N A V T R E G F K I A H D I S S Y S F V A M A K A C R S M L N P G S A L L T L S Y L G A E R A I P N Y N V M G L A K A S L E A N V R Y M A N A M G P E G V R V N A I S A G P I R T L A A S G I K D F R K M L A H C E A V T P I R R T V T I E D V G N S A A F L C S D L S A G I S G E V V H V D G G F S I A A M N E G F L S G K R I L V T G V A S K L S I A Y G I A Q A M H R E G A E L A F T Y Q N D K L K G R V E E F A A Q L G S D I V L Q C D V A E D A S I D T M F A E L G K V W P K F D G F V H S I G F A P G D Q L D G D Y V N A V T R E G F K I A H D I S S Y S F V A M A K A C R S M L N P G S A L L T L S Y L G A E R A I P N Y N V M G L A K A S L E A N V R Y M A N A M G P E G V R V N A I S A G P I R T L A A S G I K D F R K M L A H C E A V T P I R R T V T I E D V G N S A A F L C S D L S A G I S G E V V H V D G G F S I A A M N E

AH

UNSTRUCTURED

4RE4

AAPFTYWLNPEIYDAGGLSRRAFPEGFVFGTAASAYQVEGMAKQGGRGPSIWDAFIEKPGTIPNNATADVTVDEYHRYKEDVNIMKNMGFDAYRFSISWSRIFPNGTGMVNQEGVDYYNRLIDYMVKKGIKPYANLYHYDLPLALHEQYLGWLSPNIVEAFADYADFCFQTFGDRVKDWFTFNEPRCVAALGYDNGFHAPGRCSGCDAGGNSTTEPYLAAHHLILSHAAAVKRYREKYQLYQKGRIGILLDFVWYEPFSDSNADRAAAQRARDFHLGWFLDPIIHGRYPYSMLEIVKDRMPTFSDEESRMVKDSIDYVGINHYTSFYMKDPGPWNLTPTSYQDDWHVGFAYERNGVPIGAQANSYWLYIVPWGINKAVTYVKETYGNPTMILSENGMDQPGNVSITQGVHDTVRIRYYRNYITELKKAIDDGAKVIGYFAWSLLDNFEWRLGYTSRFGIVYVDYKTLKRYPKDSAFWFKNMLS

~~GGGG~~~GGGG~~TT~~GGGS~TT~EEEEE~~HHHH~~~TTSTT~~~BHHHHHHHSTTSSGGG~~SSSTT~HHHHHHHHHHHHHHTT~~EEEEE~~HHHH~TTSSSS~~HHHHHHHHHHHHHHHHTT~EEEEEEESS~~BHHHHHHH~GGGSTTHHHHHHHHHHHHHHHHTTT~~EEEEEE~HHHHHHHHHTS~~STT~~~SS~TT~~~TTTHHHHHHHHHHHHHHHHHHHHHHHTHHHH~~EEEEEEE~~EEEESSSSHHHHHHHHHHHHHHTHHHHHHHHHSS~~HHHHHHHGGGS~~~~HHHHHHHTT~~SEEEEE~~~EEEEE~~SS~~~S~~~HHHHT~~EEESEETTEESS~B~SSTT~B~~THHHHHHHHHHHHHTTS~~EEEEE~~~~EES~~~HHHHT~~HHHHHHHHHHHHHHHHHHHTT~~EEEEEEE~SB~~~~GGGTTSEE~~SEEE~TTT~~EEE~HHHHHHHHHT~

A A P F T Y W L N P E I Y D A G G L S R R A F P E G F V F G T A A S A Y Q V E G M A K Q G G R G P S I W D A F I E K P G T I P N N A T A D V T V D E Y H R Y K E D V N I M K N M G F D A Y R F S I S W S R I F P N G T G M V N Q E G V D Y Y N R L I D Y M V K K G I K P Y A N L Y H Y D L P L A L H E Q Y L G W L S P N I V E A F A D Y A D F C F Q T F G D R V K D W F T F N E P R C V A A L G Y D N G F H A P G R C S G C D A G G N S T T E P Y L A A H H L I L S H A A A V K R Y R E K Y Q L Y Q K G R I G I L L D F V W Y E P F S D S N A D R A A A Q R A R D F H L G W F L D P I I H G R Y P Y S M L E I V K D R M P T F S D E E S R M V K D S I D Y V G I N H Y T S F Y M K D P G P W N L T P T S Y Q D D W H V G F A Y E R N G V P I G A Q A N S Y W L Y I V P W G I N K A V T Y V K E T Y G N P T M I L S E N G M D Q P G N V S I T Q G V H D T V R I R Y Y R N Y I T E L K K A I D D G A K V I G Y F A W S L L D N F E W R L G Y T S R F G I V Y V D Y K T L K R Y P K D S A F W F K N M L S

AH

UNSTRUCTURED

4D1G

KTSLDIAEELQNDKGVSFAFQAREEELGAFTKRTLFAYSGDGLTGPFKAPASAELSSFLTAHPKGRWLIAFPLGTGIVSVDEGILTLEISRSLPEVGSGSSFYLTEKSKTSLDIAEELQNDKGVSFAFQAREEELGAFTKRTLFAYSGDGLTGPFKAPASAELSSFLTAHPKGRWLIAFPLGTGIVSVDEGILTLEISRSLPEVGSGSSFYLTEKSKTSLDIAEELQNDKGVSFAFQAREEELGAFTKRTLFAYSGDGLTGPFKAPASAELSSFLTAHPKGRWLIAFPLGTGIVSVDEGILTLEISRSLPEVGSGSSFYLTESKTSLDIAEELQNDKGVSFAFQAREEELGAFTKRTLFAYSGDGLTGPFKAPASAELSSFLTAHPKGRWLIAFPLGTGIVSVDEGILTLEISRSLPEVGSGSSFYLTEKTSLDIAEELQNDKGVSFAFQAREEELGAFTKRTLFAYSGDGLTGPFKAPASAELSSFLTAHPKGRWLIAFPLGTGIVSVDEGILTLEISRSLPEVGSGSSFYLTESKTSLDIAEELQNDKGVSFAFQAREEELGAFTKRTLFAYSGDGLTGPFKAPASAELSSFLTAHPKGRWLIAFPLGTGIVSVDEGILTLEISRSLPEVGSGSSFYLTESKTSLDIAEELQNDKGVSFAFQAREEELGAFTKRTLFAYSGDGLTGPFKAPASAELSSFLTAHPKGRWLIAFPLGTGIVSVDEGILTLEISRSLPEVGSGSSFYLTEKSKTSLDIAEELQNDKGVSFAFQAREEELGAFTKRTLFAYSGDGLTGPFKAPASAELSSFLTAHPKGRWLIAFPLGTGIVSVDEGILTLEISRSLPEVGSGSSFYLTESKTSLDIAEELQNDKGVSFAFQAREEELGAFTKRTLFAYSGDGLTGPFKAPASAELSSFLTAHPKGRWLIAFPLGTGIVSVDEGILTLEISRSLPEVGSGSSFYLTEKKTSLDIAEELQNDKGVSFAFQAREEELGAFTKRTLFAYSGDGLTGPFKAPASAELSSFLTAHPKGRWLIAFPLGTGIVSVDEGILTLEISRSLPEVGSGSSFYLTESKTSLDIAEELQNDKGVSFAFQAREEELGAFTKRTLFAYSGDGLTGPFKAPASAELSSFLTAHPKGRWLIAFPLGTGIVSVDEGILTLEISRSLPEVGSGSSFYLTESKTSLDIAEELQNDKGVSFAFQAREEELGAFTKRTLFAYSGDGLTGPFKAPASAELSSFLTAHPKGRWLIAFPLGTGIVSVDEGILTLEISRSLPEVGSGSSFYLTE

~EEEEEEEEEE~TTS~EEEEEEEEEEETTEEEEEEEEEESS~BSS~EEEE~~HHHHHHHH~~TTSSEEEEETTEEEEEEEETTEEEEEESS~BS~~EEEEEEEEEE~~EEEEEEEEEEE~TTS~EEEEEEEEEEETTEEEEEEEEEESS~BSS~EEEE~~HHHHHHHHT~TTSSEEEEETTEEEEEEEETTEEEEEESS~BS~~EEEEEEEEEE~~EEEEEEEEEEE~TTS~EEEEEEEEEEETTEEEEEEEEEESS~BSS~EEEE~~HHHHHHHHTSTTSSEEEEETTEEEEEEEETTEEEEEESS~BS~~EEEEEEEEE~~EEEEEEEEEEE~TTS~EEEEEEEEEEETTEEEEEEEEEESS~BSS~EEEE~~HHHHHHHHTSTTSSEEEEETTEEEEEEEETTEEEEEESS~BS~~EEEEEEEEE~~EEEEEEEEEE~TT~~EEEEEEEEEEETTEEEEEEEEEESS~BSS~EEEE~~HHHHHHHHTSTTSSEEEEETTEEEEEEEETTEEEEEESS~BS~~EEEEEEEEE~~EEEEEEEEEEE~TTS~EEEEEEEEEEETTEEEEEEEEEESS~BSS~EEEE~~HHHHHHHHTSTTSSEEEEETTEEEEEEEETTEEEEEESS~BS~~EEEEEEEEE~~EEEEEEEEEEE~TTS~EEEEEEEEEEETTEEEEEEEEEESS~BSS~EEEE~~HHHHHHHHT~TTSSEEEEETTEEEEEEEETTEEEEEESS~BS~~EEEEEEEEEE~~EEEEEEEEEEE~TTS~EEEEEEEEEEETTEEEEEEEEEESS~BSS~EEEE~~HHHHHHHHTSTTSSEEEEETTEEEEEEEETTEEEEEESS~BS~~EEEEEEEEE~~EEEEEEEEEEE~TTS~EEEEEEEEEEETTEEEEEEEEEESS~BSS~EEEE~~HHHHHHHHTSTTSSEEEEETTEEEEEEEETTEEEEEESS~BS~~EEEEEEEEEE~~EEEEEEEEEE~TTS~EEEEEEEEEEETTEEEEEEEEEESS~BSS~EEEE~~HHHHHHHHT~TTSSEEEEETTEEEEEEEETTEEEEEESS~BS~~EEEEEEEEE~~~EEEEEEEEEE~TTS~EEEEEEEEEEETTEEEEEEEEEESS~BSS~EEEE~~HHHHHHHHHSTTSSEEEEETTEEEEEEEETTEEEEEESS~BS~~EEEEEEEEE~~EEEEEEEEEEE~TTS~EEEEEEEEEEETTEEEEEEEEEESS~BSS~EEEE~~HHHHHHHHTSTTSSEEEEETTEEEEEEEETTEEEEEESS~BS~~EEEEEEEEE~

K T S L D I A E E L Q N D K G V S F A F Q A R E E E L G A F T K R T L F A Y S G D G L T G P F K A P A S A E L S S F L T A H P K G R W L I A F P L G T G I V S V D E G I L T L E I S R S L P E V G S G S S F Y L T E K S K T S L D I A E E L Q N D K G V S F A F Q A R E E E L G A F T K R T L F A Y S G D G L T G P F K A P A S A E L S S F L T A H P K G R W L I A F P L G T G I V S V D E G I L T L E I S R S L P E V G S G S S F Y L T E K S K T S L D I A E E L Q N D K G V S F A F Q A R E E E L G A F T K R T L F A Y S G D G L T G P F K A P A S A E L S S F L T A H P K G R W L I A F P L G T G I V S V D E G I L T L E I S R S L P E V G S G S S F Y L T E S K T S L D I A E E L Q N D K G V S F A F Q A R E E E L G A F T K R T L F A Y S G D G L T G P F K A P A S A E L S S F L T A H P K G R W L I A F P L G T G I V S V D E G I L T L E I S R S L P E V G S G S S F Y L T E K T S L D I A E E L Q N D K G V S F A F Q A R E E E L G A F T K R T L F A Y S G D G L T G P F K A P A S A E L S S F L T A H P K G R W L I A F P L G T G I V S V D E G I L T L E I S R S L P E V G S G S S F Y L T E S K T S L D I A E E L Q N D K G V S F A F Q A R E E E L G A F T K R T L F A Y S G D G L T G P F K A P A S A E L S S F L T A H P K G R W L I A F P L G T G I V S V D E G I L T L E I S R S L P E V G S G S S F Y L T E S K T S L D I A E E L Q N D K G V S F A F Q A R E E E L G A F T K R T L F A Y S G D G L T G P F K A P A S A E L S S F L T A H P K G R W L I A F P L G T G I V S V D E G I L T L E I S R S L P E V G S G S S F Y L T E K S K T S L D I A E E L Q N D K G V S F A F Q A R E E E L G A F T K R T L F A Y S G D G L T G P F K A P A S A E L S S F L T A H P K G R W L I A F P L G T G I V S V D E G I L T L E I S R S L P E V G S G S S F Y L T E S K T S L D I A E E L Q N D K G V S F A F Q A R E E E L G A F T K R T L F A Y S G D G L T G P F K A P A S A E L S S F L T A H P K G R W L I A F P L G T G I V S V D E G I L T L E I S R S L P E V G S G S S F Y L T E K K T S L D I A E E L Q N D K G V S F A F Q A R E E E L G A F T K R T L F A Y S G D G L T G P F K A P A S A E L S S F L T A H P K G R W L I A F P L G T G I V S V D E G I L T L E I S R S L P E V G S G S S F Y L T E S K T S L D I A E E L Q N D K G V S F A F Q A R E E E L G A F T K R T L F A Y S G D G L T G P F K A P A S A E L S S F L T A H P K G R W L I A F P L G T G I V S V D E G I L T L E I S R S L P E V G S G S S F Y L T E S K T S L D I A E E L Q N D K G V S F A F Q A R E E E L G A F T K R T L F A Y S G D G L T G P F K A P A S A E L S S F L T A H P K G R W L I A F P L G T G I V S V D E G I L T L E I S R S L P E V G S G S S F Y L T E

BS

UNSTRUCTURED

4QWW

AGELKVSTQTGSVRGLSLPVLDGHVSAFLGIPFAEPPLGRMRFLRPEPVKPWQHVLDATSYKPACYQMVDTSYPGFQGTEMWNPNRGMSEDCLYLNIWVPSPRPKDAPVLVWIYGGGFYSGAASLDVYDGRFLTYTQNVILVSLSYRVGAFGFLGLPGSPEAPGNMGLLDQRLALQWIQNNIHPFGGNPRAVTVFGESAGAASVGMHLLSTQSRTLFQRAILQSGGPNAPWATVTPAESRGRAALLGKQLGCHFNNDSELVSCLRSKNPQELIDEEWSVLPYKSIFRFPFVPVIDGDFFPDTPEAMLSSGNFKETQVLLGVVKDEGSYFLIYGLPGFSKDNESLISRADFLEGVRMSVPHANDIATDAVVLQYTDWQDQDNREKNREALDDIVGDHNVICPVVQFANDYAKRNSKVYAYLFDHRASNLLWPPWMGVPHGYEIEFVFGLPLNDSLNYTPQEKELSRRMMRYWANFARTGNPTDPAAWPTYTASQPQYVQLNTQPLATQPSLRAQICAFWNHFLPKLLNATAGELKVSTQTGSVRGLSLPVLDGHVSAFLGIPFAEPPLGRMRFLRPEPVKPWQHVLDATSYKPACYQMVDTSYPGFQGTEMWNPNRGMSEDCLYLNIWVPSPRPKDAPVLVWIYGGGFYSGAASLDVYDGRFLTYTQNVILVSLSYRVGAFGFLGLPGSPEAPGNMGLLDQRLALQWIQNNIHPFGGNPRAVTVFGESAGAASVGMHLLSTQSRTLFQRAILQSGGPNAPWATVTPAESRGRAALLGKQLGCHFNNDSELVSCLRSKNPQELIDEEWSVLPYKSIFRFPFVPVIDGDFFPDTPEAMLSSGNFKETQVLLGVVKDEGSYFLIYGLPGFSKDNESLISRADFLEGVRMSVPHANDIATDAVVLQYTDWQDQDNREKNREALDDIVGDHNVICPVVQFANDYAKRNSKVYAYLFDHRASNLLWPPWMGVPHGYEIEFVFGLPLNDSLNYTPQEKELSRRMMRYWANFARTGNPTDPAAWPTYTASQPQYVQLNTQPLATQPSLRAQICAFWNHFLPKLLNATQIVLTQSPAIMSASPGEKVTMTCSASSSVSYMYWYHQKPGSSPKPWIYRTSNLASGVPARFSGSGSGTSYSLSVSSVEAEDAATYYCQQYNSHPMTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEEVQLVESGGGLVQPKGSLKLSCAASGFTFNTYAMHWVRQAPGKGLEWVARIRSKSNKYATHYADSVKDRFTISRDDSQTMLYLQMNNLKTEDTAMYYCVREGSYYDSSYGAMDYWGQGTSVTVSSAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLESDLYTLSSSVTVPSSPWPSETVTCNVAHPASSTKVDKKIVPRQIVLTQSPAIMSASPGEKVTMTCSASSSVSYMYWYHQKPGSSPKPWIYRTSNLASGVPARFSGSGSGTSYSLSVSSVEAEDAATYYCQQYNSHPMTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEEVQLVESGGGLVQPKGSLKLSCAASGFTFNTYAMHWVRQAPGKGLEWVARIRSKSNKYATHYADSVKDRFTISRDDSQTMLYLQMNNLKTEDTAMYYCVREGSYYDSSYGAMDYWGQGTSVTVSSAKTTPPSVYPLAPGSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLESDLYTLSSSVTVPSSPWPSETVTCNVAHPASSTKVDKKIVPR

~~TTEEEETTEEEE~EEEEETTEEEEEEEEEESB~~~~GGGTTS~~~B~~~~SSEEE~BS~~~EE~~~~~~S~TT~HHHHTTS~SS~EES~~~EEEEEEESS~~SSEEEEEEE~~STTT~~~TT~GGG~~HHHHHHHT~EEEE~~~~~SHHHH~B~TT~TT~BS~HHHHHHHHHHHHHHHHSGGGTEEEEEEEEEEETHHHHHHHHHHHSTTSSSS~SEEEEES~~TT~TTT~B~HHHHHHHHHHHHHHTT~~~SSSHHHHHHHHHS~HHHHHHHHGGG~SSS~SS~~SS~~B~~SSS~SS~HHHHHHHT~S~~~~EEEEEESBSSHHHHTTTSTT~~TTS~~~~~HHHHHHHHHHHSTT~~HHHHHHHHHHT~~SSSTT~HHHHHHHHHHHHHHHHTHHHHHHHHHHHHTTT~~EEEEEE~~~~TT~SS~GGG~SBTTTTHHHHTTGGG~GGG~~~HHHHHHHHHHHHHHHHHHHTSSSS~~~~~~B~~SSS~~EEEESSS~~EEES~SSHHHHHHHHTHHHHHHHH~~~TTEEEETTEEEE~EEEEETTEEEEEEEEEE~B~~~~GGGTTS~~~B~~~~SSEEE~BS~~~EE~~~~~~S~TT~HHHHTTS~SS~EES~~~EEEEEEESS~~SSEEEEEEE~~STTT~~~TT~GGG~~HHHHHHS~~EEEE~~~~~HHHHH~~~TT~TT~~S~HHHHHHHHHHHHHHHHSGGGTEEEEEEEEEEETHHHHHHHHHHHSHHHHTT~SEEEEES~~TT~TTT~B~HHHHHHHHHHHHHHTT~~~SSHHHHHHHHHHS~HHHHHHHHGGG~SSS~SS~~SS~~B~~SSS~SS~HHHHHHHT~S~~~~EEEEEETBSSHHHHTTTSTT~~TTS~~~~~HHHHHHHHHHHSTT~~HHHHHHHHHHT~~SSSTT~HHHHHHHHHHHHHHHHTHHHHHHHHHHHHTTT~~EEEEEE~~~~TT~SS~GGG~SBTTTTHHHHTTGGG~GGG~~~HHHHHHHHHHHHHHHHHHHTSSS~~~~~~~B~~SSS~~EEEESSSS~EEES~SSHHHHHHHHTHHHHHHHH~~~~EEEE~SEEEE~TT~~EEEEEEESS~~S~~EEEEE~TTS~~EEEEETTTEE~TT~~TTEEEEEETTEEEEEESS~~GGG~EEEEEEE~SSSS~EE~~~EEEEE~~S~B~~EEEEE~~~HHHHHTTEEEEEEEEEEEBSS~EEEEEEETTEEE~TTEEEEE~~~~TTT~~EEEEEEEEEEHHHHTT~~EEEEEEEETT~SS~EEEEEES~~~~EEEEE~~SEE~TT~~EEEEEEEESS~GGGSEEEEEEE~TTS~~EEEEEE~~TTTTT~EEE~GGGTTTEEEEEETTTTEEEEEE~S~~GGG~EEEEEEEEB~TTSTTBTSEEEE~~~EEEEE~SS~~B~~EEEEE~~SS~~~~SSEEEEEEEEEEEBSS~~EEEEGGGT~~TTEEE~~~EESSS~EEEEEEEEEETTTTTTS~~EEEEEEGGGTEEEEEE~~~~~~~EEEE~SEEEE~TT~~EEEEEEESS~~S~~EEEEE~TTS~~EEEEETTTEE~TT~~TTEEEEEETTEEEEEESS~~GGG~EEEEEEE~SSSS~EE~~~EEEEE~~S~B~~EEEEE~~~HHHHHTTEEEEEEEEEEEBSS~EEEEEEETTEEE~TTEEEEE~~~~TTT~~EEEEEEEEEEHHHHTT~~EEEEEEEETT~SS~EEEEEES~~~~EEEEE~~SEE~TT~~EEEEEEEESS~GGGSEEEEEEE~TTS~~EEEEEE~~TTTTT~EEE~GGGTTTEEEEEETTTTEEEEEE~S~~GGG~EEEEEEEEB~TTSTTBTSEEEE~~~EEEEE~SS~~B~~EEEEE~~~~EEEEEEEEEEEBSS~~EEEEGGGTB~TTEEE~~~EESSS~EEEEEEEEEETTTTTTS~~EEEEEEGGGTEEEEEE~~~~

A G E L K V S T Q T G S V R G L S L P V L D G H V S A F L G I P F A E P P L G R M R F L R P E P V K P W Q H V L D A T S Y K P A C Y Q M V D T S Y P G F Q G T E M W N P N R G M S E D C L Y L N I W V P S P R P K D A P V L V W I Y G G G F Y S G A A S L D V Y D G R F L T Y T Q N V I L V S L S Y R V G A F G F L G L P G S P E A P G N M G L L D Q R L A L Q W I Q N N I H P F G G N P R A V T V F G E S A G A A S V G M H L L S T Q S R T L F Q R A I L Q S G G P N A P W A T V T P A E S R G R A A L L G K Q L G C H F N N D S E L V S C L R S K N P Q E L I D E E W S V L P Y K S I F R F P F V P V I D G D F F P D T P E A M L S S G N F K E T Q V L L G V V K D E G S Y F L I Y G L P G F S K D N E S L I S R A D F L E G V R M S V P H A N D I A T D A V V L Q Y T D W Q D Q D N R E K N R E A L D D I V G D H N V I C P V V Q F A N D Y A K R N S K V Y A Y L F D H R A S N L L W P P W M G V P H G Y E I E F V F G L P L N D S L N Y T P Q E K E L S R R M M R Y W A N F A R T G N P T D P A A W P T Y T A S Q P Q Y V Q L N T Q P L A T Q P S L R A Q I C A F W N H F L P K L L N A T A G E L K V S T Q T G S V R G L S L P V L D G H V S A F L G I P F A E P P L G R M R F L R P E P V K P W Q H V L D A T S Y K P A C Y Q M V D T S Y P G F Q G T E M W N P N R G M S E D C L Y L N I W V P S P R P K D A P V L V W I Y G G G F Y S G A A S L D V Y D G R F L T Y T Q N V I L V S L S Y R V G A F G F L G L P G S P E A P G N M G L L D Q R L A L Q W I Q N N I H P F G G N P R A V T V F G E S A G A A S V G M H L L S T Q S R T L F Q R A I L Q S G G P N A P W A T V T P A E S R G R A A L L G K Q L G C H F N N D S E L V S C L R S K N P Q E L I D E E W S V L P Y K S I F R F P F V P V I D G D F F P D T P E A M L S S G N F K E T Q V L L G V V K D E G S Y F L I Y G L P G F S K D N E S L I S R A D F L E G V R M S V P H A N D I A T D A V V L Q Y T D W Q D Q D N R E K N R E A L D D I V G D H N V I C P V V Q F A N D Y A K R N S K V Y A Y L F D H R A S N L L W P P W M G V P H G Y E I E F V F G L P L N D S L N Y T P Q E K E L S R R M M R Y W A N F A R T G N P T D P A A W P T Y T A S Q P Q Y V Q L N T Q P L A T Q P S L R A Q I C A F W N H F L P K L L N A T Q I V L T Q S P A I M S A S P G E K V T M T C S A S S S V S Y M Y W Y H Q K P G S S P K P W I Y R T S N L A S G V P A R F S G S G S G T S Y S L S V S S V E A E D A A T Y Y C Q Q Y N S H P M T F G G G T K L E I K R A D A A P T V S I F P P S S E Q L T S G G A S V V C F L N N F Y P K D I N V K W K I D G S E R Q N G V L N S W T D Q D S K D S T Y S M S S T L T L T K D E Y E R H N S Y T C E A T H K T S T S P I V K S F N R N E E V Q L V E S G G G L V Q P K G S L K L S C A A S G F T F N T Y A M H W V R Q A P G K G L E W V A R I R S K S N K Y A T H Y A D S V K D R F T I S R D D S Q T M L Y L Q M N N L K T E D T A M Y Y C V R E G S Y Y D S S Y G A M D Y W G Q G T S V T V S S A K T T P P S V Y P L A P G S A A Q T N S M V T L G C L V K G Y F P E P V T V T W N S G S L S S G V H T F P A V L E S D L Y T L S S S V T V P S S P W P S E T V T C N V A H P A S S T K V D K K I V P R Q I V L T Q S P A I M S A S P G E K V T M T C S A S S S V S Y M Y W Y H Q K P G S S P K P W I Y R T S N L A S G V P A R F S G S G S G T S Y S L S V S S V E A E D A A T Y Y C Q Q Y N S H P M T F G G G T K L E I K R A D A A P T V S I F P P S S E Q L T S G G A S V V C F L N N F Y P K D I N V K W K I D G S E R Q N G V L N S W T D Q D S K D S T Y S M S S T L T L T K D E Y E R H N S Y T C E A T H K T S T S P I V K S F N R N E E V Q L V E S G G G L V Q P K G S L K L S C A A S G F T F N T Y A M H W V R Q A P G K G L E W V A R I R S K S N K Y A T H Y A D S V K D R F T I S R D D S Q T M L Y L Q M N N L K T E D T A M Y Y C V R E G S Y Y D S S Y G A M D Y W G Q G T S V T V S S A K T T P P S V Y P L A P G S M V T L G C L V K G Y F P E P V T V T W N S G S L S S G V H T F P A V L E S D L Y T L S S S V T V P S S P W P S E T V T C N V A H P A S S T K V D K K I V P R

BS

UNSTRUCTURED

1YV7

DWLTFQKKHITNTRDVDCDNIMSTNLFHCKDKNTFIYSRPEPVKAICKGIIASKNVLTTSEFYLSDCNVTSRPCKYKLKKSTNKFSVTCENQAPVHFVGVG

~HHHHHHHHEES~SS~~HHHHTTSTTTTT~SEEEEEES~HHHHHGGGTT~~S~EEEE~SS~EEEEEEEE~SSTT~EEEEEEEE~EEEEEETTEEEEEEEE~

D W L T F Q K K H I T N T R D V D C D N I M S T N L F H C K D K N T F I Y S R P E P V K A I C K G I I A S K N V L T T S E F Y L S D C N V T S R P C K Y K L K K S T N K F S V T C E N Q A P V H F V G V G

BS

AH

2WO6

RKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKARPGTPAL

~~HHHHHTB~TTS~B~~~TT~EETTTEEEEEEEEEETTEEEEEEEETTTTEEEEEEEE~SSHHHHHHHHHHHHHHHHHHT~~SGGGGGB~~EEEEEEETTEEEEEEE~~~~BHHHHHHHTTTS~~~HHHHHHHHHHHHHHHHHHTSTTT~EE~~~~SGGGEEES~TTS~~EEE~~GGG~EETTS~~~~~~~GGG~~HHHHTT~~~~THHHHHHHHHHHHHHHHSS~SS~~SSHHHHHHHHHHHH~S~~HHHHTT~TTHHHHEEE~TTS~EEE~~~~~~~~TT~S~HHHHTTTTTTSGGGTTTT~SS~~HHHHHHHHHHHHHHT~S~TTTS~~HHHHTTSGGG~~~GGGTB~TTS~B~~~TT~EETTTEEEEEEEEEETTEEEEEEEETTTTEEEEEEEE~SSHHHHHHHHHHHHHHHHHTT~~~GGGGGB~~EEEEEEETTEEEEEEE~~~~BHHHHHHHTTTS~~~HHHHHHHHHHHHHHHHHHTSTTT~EE~S~~SGGGEEESSTTS~~EEE~~~TT~EETT~~~~~~~~GGG~~HHHHTT~~~~THHHHHHHHHHHHHHHHSS~SS~~SSHHHHHHHHHHHH~S~~HHHHTT~TTHHHHEEE~TTS~EEE~~~~S~~TT~S~HHHHTTTTTTSGGGTTTT~TT~~HHHHHHHHHHHHHHT~S~TTTS~~HHHHTTSGGG~~~~~~~~~

R K V Y N D G Y D D D N Y D Y I V K N G E K W M D R Y E I D S L I G K G S F G Q V V K A Y D R V E Q E W V A I K I I K N K K A F L N Q A Q I E V R L L E L M N K H D T E M K Y Y I V H L K R H F M F R N H L C L V F E M L S Y N L Y D L L R N T N F R G V S L N L T R K F A Q Q M C T A L L F L A T P E L S I I H C D L K P E N I L L C N P K R S A I K I V D F G S S C Q L G Q R I Y Q I Q S R F Y R S P E V L L G M P Y D L A I D M W S L G C I L V E M H T G E P L F S G A N E V D Q M N K I V E V L G I P P A H I L D Q A P K A R K F F E K L P D G T W N L K K T R E Y K P P G T R K L H N I L G V E T G G P G G R R A G E S G H T V A D Y L K F K D L I L R M L D Y D P K T R I Q P Y Y A L Q H S F F K K Y N D G Y D D D N Y D Y I V K N G E K W M D R Y E I D S L I G K G S F G Q V V K A Y D R V E Q E W V A I K I I K N K K A F L N Q A Q I E V R L L E L M N K H D T E M K Y Y I V H L K R H F M F R N H L C L V F E M L S Y N L Y D L L R N T N F R G V S L N L T R K F A Q Q M C T A L L F L A T P E L S I I H C D L K P E N I L L C N P K R S A I K I V D F G S S C Q L G Q R I Y Q I Q S R F Y R S P E V L L G M P Y D L A I D M W S L G C I L V E M H T G E P L F S G A N E V D Q M N K I V E V L G I P P A H I L D Q A P K A R K F F E K L P D G T W N L K K R E Y K P P G T R K L H N I L G V E T G G P G G R R A G E S G H T V A D Y L K F K D L I L R M L D Y D P K T R I Q P Y Y A L Q H S F F K A R P G T P A L

AH

UNSTRUCTURED

1LC1

GDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGFTYTDANKNKGITWKEETLMEYLENPKKYIPGTKMIFAGIKKKTEREDLIAYLKKATNE

~~HHHHHHHHHHHTTTT~~~TTT~~~SSSE~~TT~TT~~SS~~SS~~~~HHHHHH~~~~SHHHHHHHHHSHHHHSTT~~~TT~~~SSHHHHHHHHHHHHHTTT~

G D V E K G K K I F V Q K C A Q C H T V E K G G K H K T G P N L H G L F G R K T G Q A P G F T Y T D A N K N K G I T W K E E T L M E Y L E N P K K Y I P G T K M I F A G I K K K T E R E D L I A Y L K K A T N E

AH

UNSTRUCTURED

4XA1

PLKPEEHEDILNKLLDPELAQSERTEALQQLRVNYGSFVSEYNDLTKSKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIEKERDFYFGKLRNIELICQENEGENDPVLQRIVDILYATPLKPEEHEDILNKLLDPELAQSERTEALQQLRVNYGSFVSEYNDLTKSKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIEKERDFYFGKLRNIELICQENEGENDPVLQRIVDILYATDERTEALQQLRVNYGSFVSEYNDLTKSKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIEKERDFYFGKLRNIELICQENEGENDPVLQRIVDILYATPLKPEEHEDILNKLDLTKSKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIEKERDFYFGKLRNIELICQENEGENDPVLQRIVDILY

~~~HHHHTTTTTTTTSTTS~TTTTTHHHHHHHHHHHHHHHHHS~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTT~~HHHHHHHHHHT~~~~~HHHHHHHHHHTT~TTS~TTHHHHHTTHHHHHHHHTTGGGGT~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTGGG~~HHHHHHHHHHT~~~~~~HHHHHHHHHHHHHHHHHS~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTS~~TTHHHHHHHHT~~~~~TTHHHHEEE~~~~~TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTT~HHHHHHHHHT~

P L K P E E H E D I L N K L L D P E L A Q S E R T E A L Q Q L R V N Y G S F V S E Y N D L T K S K M R R D L E E A T L Q H E A T A A A L R K K H A D S V A E L G E Q I D N L Q R V K Q K L E K E K S E F K L E L D D V T S N M E Q I E K E R D F Y F G K L R N I E L I C Q E N E G E N D P V L Q R I V D I L Y A T P L K P E E H E D I L N K L L D P E L A Q S E R T E A L Q Q L R V N Y G S F V S E Y N D L T K S K M R R D L E E A T L Q H E A T A A A L R K K H A D S V A E L G E Q I D N L Q R V K Q K L E K E K S E F K L E L D D V T S N M E Q I E K E R D F Y F G K L R N I E L I C Q E N E G E N D P V L Q R I V D I L Y A T D E R T E A L Q Q L R V N Y G S F V S E Y N D L T K S K M R R D L E E A T L Q H E A T A A A L R K K H A D S V A E L G E Q I D N L Q R V K Q K L E K E K S E F K L E L D D V T S N M E Q I E K E R D F Y F G K L R N I E L I C Q E N E G E N D P V L Q R I V D I L Y A T P L K P E E H E D I L N K L D L T K S K M R R D L E E A T L Q H E A T A A A L R K K H A D S V A E L G E Q I D N L Q R V K Q K L E K E K S E F K L E L D D V T S N M E Q I E K E R D F Y F G K L R N I E L I C Q E N E G E N D P V L Q R I V D I L Y

AH

T

4EAC

SHMEQTWRWYGPNDPVSLADVRQAGATGVVTALHHIPNGEVWSVEEILKRKAIIEDAGLVWSVVESVPIHEDIKTHTGNYEQWIANYQQTLRNLAQCGIRTVCYNFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAERFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKAIIPVAEEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYGVRADNDLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNGDVDMYEVVKAIVEEEHRRKAEGKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFFSSHMEQTWRWYGPNDPVSLADVRQAGATGVVTALHHIPNGEVWSVEEILKRKAIIEDAGLVWSVVESVPIHEDIKTHTGNYEQWIANYQQTLRNLAQCGIRTVCYNFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAERFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKAIIPVAEEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYGVRADNDLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNGDVDMYEVVKAIVEEEHRRKAEGKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFFSSHMEQTWRWYGPNDPVSLADVRQAGATGVVTALHHIPNGEVWSVEEILKRKAIIEDAGLVWSVVESVPIHEDIKTHTGNYEQWIANYQQTLRNLAQCGIRTVCYNFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAERFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKAIIPVAEEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYGVRADNDLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNGDVDMYEVVKAIVEEEHRRKAEGKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFFSRSHMEQTWRWYGPNDPVSLADVRQAGATGVVTALHHIPNGEVWSVEEILKRKAIIEDAGLVWSVVESVPIHEDIKTHTGNYEQWIANYQQTLRNLAQCGIRTVCYNFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAERFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKAIIPVAEEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYGVRADNDLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNGDVDMYEVVKAIVEEEHRRKAEGKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFFS

~~S~BEEE~~~TT~SS~HHHHHHHT~~EEEE~~TTS~TTS~~~HHHHHHHHHHHHHTT~EEEEEE~~~~~HHHHHT~TTHHHHHHHHHHHHHHHHHTT~~EEEE~~~~S~~S~~SEEEEE~TTS~EEEEE~HHHHHHHHHHTS~~TTGGGGS~HHHHHHHHHHHHT~~HHHHHHHHHHHHS~~TT~S~~~~HHHHHHHHHTTTT~~HHHHHHHHHHHHHHHHHHHHHHT~EEEE~~~SSSS~~TT~~~~SSSHHHHHHHHHH~~~TTEEEEEEHHHHTTSTT~~HHHHHHHHGGGEEEEE~~~EEE~SSTT~EEE~~TTSSSS~HHHHHHHHHHHHHHHHHTT~~~~~~EE~~~~~B~GGGGGS~~STT~~SHHHHHHHHHHHHHHHHHHHHH~~~~S~BEEE~~~TT~SS~HHHHHHHT~~EEEE~~TTS~TTS~~~HHHHHHHHHHHHHTT~EEEEEE~~~~~HHHHHT~TTHHHHHHHHHHHHHHHHHTT~~EEEE~~~~S~~S~~SEEEEE~TTS~EEEEE~HHHHHHHHHHTT~~TTGGGGS~HHHHHHHHHHHHT~~HHHHHHHHHHHHS~~TT~S~~~~HHHHHHHGGGGTT~~HHHHHHHHHHHHHHHHHHHHHHT~EEEE~~~SSSS~~TT~~~~SSSHHHHHHHHHH~~STTEEEEEEHHHHTTSTT~~HHHHHHHHGGGEEEEE~~~EEE~SSTT~EEE~~TTTSSS~HHHHHHHHHHHHHHHHHTS~~~~~~EE~~~~~B~GGGGGS~~~TT~~HHHHHHHHHHHHHHHHHHHHHH~~~~~~BEEE~~~TT~SS~HHHHHHHT~~EEEE~~TTS~TT~~~~HHHHHHHHHHHHHTT~EEEEEE~~~~~HHHHTT~TTHHHHHHHHHHHHHHHHHTT~~EEEE~~~SS~~S~~SEEEEE~TTS~EEEEE~HHHHHHHHHHTT~~TTGGGGS~HHHHHHHHHHHTT~~HHHHHHHHHHHHS~~TT~~~~~~HHHHHHHHTTSTT~~HHHHHHHHHHHHHHHHHHHHHHT~EEEE~~~SSSS~~TT~~~~SSSHHHHHHHHHH~~~TTEEEEEEHHHHTTSTT~~HHHHHHHHGGGEEEEE~~~EEE~SSTT~EEE~~TTSSSS~HHHHHHHHHHHHHHHHHHTS~~~~~EE~~~~~B~GGGGGS~~~TT~~HHHHHHHHHHHHHHHHHHHHHHTT~~~S~BEEE~~~TT~SS~HHHHHHHT~~EEEE~~TTS~TT~~~~HHHHHHHHHHHHHTT~EEEEEE~~~~~HHHHHT~TTHHHHHHHHHHHHHHHHHTT~~EEEE~~~~S~~S~~SEEEEE~TTS~EEEEE~HHHHHHHHHHTT~~TTGGGGS~HHHHHHHHHHHHT~~HHHHHHHHHHHHS~~TT~~~~~~HHHHHHHHGGGTT~~HHHHHHHHHHHHHHHHHHHHHHT~EEEE~~~SSSS~BTTB~~SSSSHHHHHHHHHH~~STTEEEEEEHHHHTTSTT~~HHHHHHHHGGGEEEEE~~~EEE~SSTT~EEE~~TTSSSS~HHHHHHHHHHHHHHHHHTT~~~~~~EE~~~~~B~GGGGGS~~~TT~~HHHHHHHHHHHHHHHHHHHHHHH~

S H M E Q T W R W Y G P N D P V S L A D V R Q A G A T G V V T A L H H I P N G E V W S V E E I L K R K A I I E D A G L V W S V V E S V P I H E D I K T H T G N Y E Q W I A N Y Q Q T L R N L A Q C G I R T V C Y N F M P V L D W T R T D L E Y V L P D G S K A L R F D Q I E F A A F E M H I L K R P G A E A D Y T E E E I A Q A A E R F A T M S D E D K A R L T R N I I A G L P G A E E G Y T L D Q F R K H L E L Y K D I D K A K L R E N F A V F L K A I I P V A E E V G V R M A V H P D D P P R P I L G L P R I V S T I E D M Q W M V D T V N S M A N G F T M C T G S Y G V R A D N D L V D M I K Q F G P R I Y F T H L R S T M R E D N P K T F H E A A H L N G D V D M Y E V V K A I V E E E H R R K A E G K E D L I P M R P D H G H Q M L D D L K K K T N P G Y S A I G R L K G L A E V R G V E L A I Q R A F F S S H M E Q T W R W Y G P N D P V S L A D V R Q A G A T G V V T A L H H I P N G E V W S V E E I L K R K A I I E D A G L V W S V V E S V P I H E D I K T H T G N Y E Q W I A N Y Q Q T L R N L A Q C G I R T V C Y N F M P V L D W T R T D L E Y V L P D G S K A L R F D Q I E F A A F E M H I L K R P G A E A D Y T E E E I A Q A A E R F A T M S D E D K A R L T R N I I A G L P G A E E G Y T L D Q F R K H L E L Y K D I D K A K L R E N F A V F L K A I I P V A E E V G V R M A V H P D D P P R P I L G L P R I V S T I E D M Q W M V D T V N S M A N G F T M C T G S Y G V R A D N D L V D M I K Q F G P R I Y F T H L R S T M R E D N P K T F H E A A H L N G D V D M Y E V V K A I V E E E H R R K A E G K E D L I P M R P D H G H Q M L D D L K K K T N P G Y S A I G R L K G L A E V R G V E L A I Q R A F F S S H M E Q T W R W Y G P N D P V S L A D V R Q A G A T G V V T A L H H I P N G E V W S V E E I L K R K A I I E D A G L V W S V V E S V P I H E D I K T H T G N Y E Q W I A N Y Q Q T L R N L A Q C G I R T V C Y N F M P V L D W T R T D L E Y V L P D G S K A L R F D Q I E F A A F E M H I L K R P G A E A D Y T E E E I A Q A A E R F A T M S D E D K A R L T R N I I A G L P G A E E G Y T L D Q F R K H L E L Y K D I D K A K L R E N F A V F L K A I I P V A E E V G V R M A V H P D D P P R P I L G L P R I V S T I E D M Q W M V D T V N S M A N G F T M C T G S Y G V R A D N D L V D M I K Q F G P R I Y F T H L R S T M R E D N P K T F H E A A H L N G D V D M Y E V V K A I V E E E H R R K A E G K E D L I P M R P D H G H Q M L D D L K K K T N P G Y S A I G R L K G L A E V R G V E L A I Q R A F F S R S H M E Q T W R W Y G P N D P V S L A D V R Q A G A T G V V T A L H H I P N G E V W S V E E I L K R K A I I E D A G L V W S V V E S V P I H E D I K T H T G N Y E Q W I A N Y Q Q T L R N L A Q C G I R T V C Y N F M P V L D W T R T D L E Y V L P D G S K A L R F D Q I E F A A F E M H I L K R P G A E A D Y T E E E I A Q A A E R F A T M S D E D K A R L T R N I I A G L P G A E E G Y T L D Q F R K H L E L Y K D I D K A K L R E N F A V F L K A I I P V A E E V G V R M A V H P D D P P R P I L G L P R I V S T I E D M Q W M V D T V N S M A N G F T M C T G S Y G V R A D N D L V D M I K Q F G P R I Y F T H L R S T M R E D N P K T F H E A A H L N G D V D M Y E V V K A I V E E E H R R K A E G K E D L I P M R P D H G H Q M L D D L K K K T N P G Y S A I G R L K G L A E V R G V E L A I Q R A F F S

AH

UNSTRUCTURED

3IJY

IVMTQSPSSLAVSAGEKVTMSCKSSQSLLNSRTRKNYLAWYQQKPGQSPKLLIYWASTRESGVPDRFTGSGSGTDFTLTISSVQAEDLAVYYCKQSNNLRTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNREVMLVESGGGLVQPGNSLRLSCATSGFTFTDYYMSWVRQPPGKALEWLGFIRNKAKGYTTEYSASVKGRFTISRDNSQSILYLQMNTLRAEDSATYYCARDISPSYGVYYEGFAYWGQGTLVTVSAATTTAPSVYPLVPGGSSVTLGCLVKGYFPEPVTVKWNYGALSSGVRTVSSVLQSGFYSLSSLVTVPSSTWPSQTVICNVAHPASKTELIKRIEPRIVMTQSPSSLAVSAGEKVTMSCKSSQSLLNSRTRKNYLAWYQQKPGQSPKLLIYWASTRESGVPDRFTGSGSGTDFTLTISSVQAEDLAVYYCKQSNNLRTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRECEVMLVESGGGLVQPGNSLRLSCATSGFTFTDYYMSWVRQPPGKALEWLGFIRNKAKGYTTEYSASVKGRFTISRDNSQSILYLQMNTLRAEDSATYYCARDISPSYGVYYEGFAYWGQGTLVTVSAATTTAPSVYPLVPGSSVTLGCLVKGYFPEPVTVKWNYGALSSGVRTVSSVLQSGFYSLSSLVTVPSSTWPSQTVICNVAHPASKTELIKRIEPR

~~EEEE~SEEEEETT~~EEEEEEESS~~EETTTTEE~EEEEEE~TTS~~EEEEETTTEE~TT~~TTEEEEEETTEEEEEESS~~GGG~EEEEEEE~SSS~EE~~~EEEEEE~~~B~~EEEEE~~~HHHHHTTEEEEEEEEEEEBSS~~EEEEEESSSEE~TTEEEEE~~~~TTT~~EEEEEEEEEEHHHHHT~~EEEEEEE~TT~SS~EEEEEE~~~EEEEE~~EEE~TT~~EEEEEEEESS~GGGS~EEEEEE~TTS~~EEEEEE~~GGGTS~EEE~GGGTTTEEEEEETTTTEEEEEE~S~~GGG~EEEEEEE~~~~SSS~~~SS~~~B~~~EEEEE~SS~~B~~EEEEE~~~~~EEEEEEEEEEEBSS~~EEEEGGGT~~SS~EE~~~EEETTEEEEEEEEEEETTTTTTS~~EEEEEEGGGTEEEEEE~~~~~~EEEE~SEEEEETT~~EEEEEEESS~~EETTTTEE~EEEEEE~TTS~~EEEEETTTEE~TT~~TTEEEEEETTEEEEEESS~~GGG~EEEEEEE~SSS~EE~~~EEEEEE~~~B~~EEEEE~~~HHHHTTTEEEEEEEEEEEBSS~~EEEEEETTEEE~TTEEEEE~~~~TTT~~EEEEEEEEEEHHHHHT~~EEEEEEE~TT~SS~EEEEEETT~~~EEEEE~~EEE~TT~~EEEEEEEESS~GGGS~EEEEEE~TTS~~EEEEEE~~TTTTS~EEE~TTTTTTEEEEEETTTTEEEEEE~S~~GGG~EEEEEEE~~~~SSS~~~SS~~~B~~~EEEEE~S~~~B~~EEEEE~~~~EEEEEEEEEEEBSS~~EEEEGGGT~~TTEEE~~~EEETTEEEEEEEEEEETTTTTTS~EEEEEEEGGGTEEEEEEE~~~

I V M T Q S P S S L A V S A G E K V T M S C K S S Q S L L N S R T R K N Y L A W Y Q Q K P G Q S P K L L I Y W A S T R E S G V P D R F T G S G S G T D F T L T I S S V Q A E D L A V Y Y C K Q S N N L R T F G G G T K L E I K R A D A A P T V S I F P P S S E Q L T S G G A S V V C F L N N F Y P K D I N V K W K I D G S E R Q N G V L N S W T D Q D S K D S T Y S M S S T L T L T K D E Y E R H N S Y T C E A T H K T S T S P I V K S F N R E V M L V E S G G G L V Q P G N S L R L S C A T S G F T F T D Y Y M S W V R Q P P G K A L E W L G F I R N K A K G Y T T E Y S A S V K G R F T I S R D N S Q S I L Y L Q M N T L R A E D S A T Y Y C A R D I S P S Y G V Y Y E G F A Y W G Q G T L V T V S A A T T T A P S V Y P L V P G G S S V T L G C L V K G Y F P E P V T V K W N Y G A L S S G V R T V S S V L Q S G F Y S L S S L V T V P S S T W P S Q T V I C N V A H P A S K T E L I K R I E P R I V M T Q S P S S L A V S A G E K V T M S C K S S Q S L L N S R T R K N Y L A W Y Q Q K P G Q S P K L L I Y W A S T R E S G V P D R F T G S G S G T D F T L T I S S V Q A E D L A V Y Y C K Q S N N L R T F G G G T K L E I K R A D A A P T V S I F P P S S E Q L T S G G A S V V C F L N N F Y P K D I N V K W K I D G S E R Q N G V L N S W T D Q D S K D S T Y S M S S T L T L T K D E Y E R H N S Y T C E A T H K T S T S P I V K S F N R E C E V M L V E S G G G L V Q P G N S L R L S C A T S G F T F T D Y Y M S W V R Q P P G K A L E W L G F I R N K A K G Y T T E Y S A S V K G R F T I S R D N S Q S I L Y L Q M N T L R A E D S A T Y Y C A R D I S P S Y G V Y Y E G F A Y W G Q G T L V T V S A A T T T A P S V Y P L V P G S S V T L G C L V K G Y F P E P V T V K W N Y G A L S S G V R T V S S V L Q S G F Y S L S S L V T V P S S T W P S Q T V I C N V A H P A S K T E L I K R I E P R

BS

UNSTRUCTURED

4ZV1

HMRGTLRVGTEATFPPFGFKDENGKLVGFDIDLAKAIAKKLGVKVEFKPMDFDGIIPALQSGKIDVVIAGMTITEERKKQVDFSDPYFEAGQAIVVKKGNDSIKSLEDLKGKKVGVQLGSTSEQHVKKVAKDAGVKVKKFDNFSEAFQELKSGRVDAVVTDNAVALAYVKQNPNAGVKIVGETFSGEPYGIAVRKGNSELLEKINKALEEMKKDGTYDKIYEKWFG

~~~~EEEEEE~SSBTTTBEE~TTS~EESHHHHHHHHHHHHHT~EEEEEE~~GGGHHHHHHTTS~SEE~SS~B~~HHHHTTEEE~S~~EEE~EEEEEETT~~S~SSGGGGTT~EEEEETTSHHHHHHHHHHHHHT~EEEEESSHHHHHHHHHHTS~SEEEEEHHHHHHHHHT~TTS~EEEES~~~~SEEE~~EEETT~HHHHHHHHHHHHHHHHSSHHHHHHHHHH~

H M R G T L R V G T E A T F P P F G F K D E N G K L V G F D I D L A K A I A K K L G V K V E F K P M D F D G I I P A L Q S G K I D V V I A G M T I T E E R K K Q V D F S D P Y F E A G Q A I V V K K G N D S I K S L E D L K G K K V G V Q L G S T S E Q H V K K V A K D A G V K V K K F D N F S E A F Q E L K S G R V D A V V T D N A V A L A Y V K Q N P N A G V K I V G E T F S G E P Y G I A V R K G N S E L L E K I N K A L E E M K K D G T Y D K I Y E K W F G

AH

BS

4JBF

SAYVQRGAIITSDGVTLAESVQDDTYVRNYPHDGASHTVGYISTQYGTAGIESSNETLTDWRSALYSAGINTTGSSVVLTINSQQAVAEAALQGYSGSIVVDPSTGAVLAKASSPSYTHAELGTSQLVDRTTQALYSPGSSFKTVTLAAGIDTHKTTLDTTYSAPGTEIGGGTIHNYANEDGTIPLREAFARSSNTALAQLGVALGADNLVSYARAFGYGTALGQDFSTTPSLPNPAETTWELAWASCGLPVGEHASPAGPQTTVQNAVIAAAIANGGVVNPYIVDRVLSPEAVVSTTSPKSLGQAVSADTAAQVREALGVVESGTGGARVPGVKIAGKTGTADVNGNFNSFFIGFAPYDHPTLVVSVVIEGNGNVLGYGAQVGGRVLAQCLNIQALSAYVQRGAIITSDGVTLAESVQDDVRNYPHDGASHTVGYISTQYGTAGIESSNETLTWRSALYSAGITTGSSVVLTINSQQAVAEAALQGYSGSIVVDPSTGAVLAKASSPSYTHAELGTISQLVDRTTQALYSPGSSFKTVTLAAGIDTHKTTLDTTYSAPGTEIGGGTIHNYANEDGTIPLREAFARSSNTALAQLGVALGADNLVSYARAFGYGTALGQDFSTTPSLPNPAETTWELAWASCGLPVGEHASPAGPQTTVQNAVIAAAIANGGVVNPYIVDRVLSPEGAVVSTTSPKSLGQAVSADTAAQVREALGVVESGTGGARVPGVKIAGKTGTADVENGNFNSFFIGFAPYDHPTLVVSVVIEGNGENVLGYGAQVGGRVLAQCLNIQAL

~~~S~~~~EE~TTS~EEE~~~~~~~~~~~~TT~~~HHHH~EEETTTEEEHHHH~~TTT~~TTTT~~~~TTT~~~~EEEES~~~~~HHHHHHHTT~EEEEE~~TTT~B~S~EEEES~~~SGGGG~~TTS~TTTS~~B~~GGGGHHHHHHHHHHTTS~~TT~EEE~~~~~BTTB~~~~GGG~~~EEEHHHHHHTT~HHHHHHHHHHH~HHHHHHHHHHTTTTS~~~SSS~~~~~~~~TT~~HHHHHHHTTT~~~~~SSS~~S~~B~~~HHHHHHHHHTTTB~~~B~EEEEE~~~~EEEE~~~~~~~BSS~HHHHHHHHH~~HHHHHS~~~~~BTTB~~EEEEEE~~~~~~~~EEEEEEESSSS~~EEEEEEEE~~~~~TTHHHHHHHHHHHHHHHHHH~~TTS~~~~EE~TTS~EEE~~~~~~~~~~TT~~~HHHH~EEETTTEEEHHHH~~TTT~~GGG~~~~~~~~~~EEEES~~~~~HHHHHHHTT~~EEEE~~TTT~B~S~EEEES~~~SGGGG~~~TTS~TTTS~~B~~GGGGHHHHHHHHHHTTS~~TT~EEE~~~~~BTTB~~~~GGG~~~EEEHHHHHHTT~HHHHHHHHHHH~HHHHHHHHHHTTTTS~~~SSS~~~~~~~~TT~~HHHHHHHTTT~~~~~SSS~~S~~B~~~HHHHHHHHHTTTB~~~B~EEEEE~TTS~EEEE~~~~~~~BSS~HHHHHHHHH~~HHHHHS~~~~~BTTB~~EEEEEE~~GGGT~~~EEEEEEESSSS~~EEEEEEE~~SSS~~TTHHHHHHHHHHHHHHHHHH~

S A Y V Q R G A I I T S D G V T L A E S V Q D D T Y V R N Y P H D G A S H T V G Y I S T Q Y G T A G I E S S N E T L T D W R S A L Y S A G I N T T G S S V V L T I N S Q Q A V A E A A L Q G Y S G S I V V D P S T G A V L A K A S S P S Y T H A E L G T S Q L V D R T T Q A L Y S P G S S F K T V T L A A G I D T H K T T L D T T Y S A P G T E I G G G T I H N Y A N E D G T I P L R E A F A R S S N T A L A Q L G V A L G A D N L V S Y A R A F G Y G T A L G Q D F S T T P S L P N P A E T T W E L A W A S C G L P V G E H A S P A G P Q T T V Q N A V I A A A I A N G G V V N P Y I V D R V L S P E A V V S T T S P K S L G Q A V S A D T A A Q V R E A L G V V E S G T G G A R V P G V K I A G K T G T A D V N G N F N S F F I G F A P Y D H P T L V V S V V I E G N G N V L G Y G A Q V G G R V L A Q C L N I Q A L S A Y V Q R G A I I T S D G V T L A E S V Q D D V R N Y P H D G A S H T V G Y I S T Q Y G T A G I E S S N E T L T W R S A L Y S A G I T T G S S V V L T I N S Q Q A V A E A A L Q G Y S G S I V V D P S T G A V L A K A S S P S Y T H A E L G T I S Q L V D R T T Q A L Y S P G S S F K T V T L A A G I D T H K T T L D T T Y S A P G T E I G G G T I H N Y A N E D G T I P L R E A F A R S S N T A L A Q L G V A L G A D N L V S Y A R A F G Y G T A L G Q D F S T T P S L P N P A E T T W E L A W A S C G L P V G E H A S P A G P Q T T V Q N A V I A A A I A N G G V V N P Y I V D R V L S P E G A V V S T T S P K S L G Q A V S A D T A A Q V R E A L G V V E S G T G G A R V P G V K I A G K T G T A D V E N G N F N S F F I G F A P Y D H P T L V V S V V I E G N G E N V L G Y G A Q V G G R V L A Q C L N I Q A L

UNSTRUCTURED

AH

5V2I

TTNKPIVLSTWNFGLHANVEAWKVLSKGGKALDAVEKGVRLVEDDPTERSVGYGGRPDRDGRVTLDACIMDENYNIGSVACMEHIKNPISVARAVMEKTPHVMLVGDGALEFALSQGFKKENLLTAESEKEWKEWLTIGMIALDAQGNLSGACTTSDMAYKMHGRVGDSPIIGAGLFVDNEIGAATATGHGEEVIRTVGTHLVVELMNQGRTPQQACKEAVERIVKIVNRRGKNLKDIQVGFIALNKKGEYGAYCIQDGFNFAVHDQKGNRLETPGFALKTTNKPIVLSTWNFGLHANVEAWKVLSKGGKALDAVEKGVRLVEDGRPDRDGRVTLDACIMDENYNIGSVACMEHIKNPISVARAVMEKTPHVMLVGDGALEFALSQGFKKENLLTAESEKEWKEWLTIGMIALDAQGNLSGACTTSDMAYKMHGRVGDSPIIGAGLFVDNEIGAATATGHGEEVIRTVGTHLVVELMNQGRTPQQACKEAVERIVKIVNRRGKNLKDIQVGFIALNKKGEYGAYCIQDGFNFAVHDQKGNRLETPGFALK

~~~~SEEEEESTTHHHHHHHHHHHHTTT~~HHHHHHHHHHHHHH~TT~TTSSTT~~~~TTS~~~EEEEEE~TTS~EEEEEEE~S~S~HHHHHHHHHHHSS~SEEEHHHHHHHHHHTT~~~~~~~~HHHHHHHHHH~~EEEEEE~TTS~EEEEEEE~~STT~~TTB~~STTSBTTTEEEETTTEEEEEEE~HHHHHHHTHHHHHHHHHHTT~~HHHHHHHHHHHHHHHHHHTT~~GGG~~EEEEEEETTS~EEEEESSTT~~EEEEETTEEEEE~~EES~~~~~~SEEEEETTHHHHHHHHHHHHHTTT~~HHHHHHHHHHHHH~~~~~TTS~~EEEEEEE~TTS~EEEEEEEES~S~HHHHHHHHHHHSS~SEEEHHHHHHHHHHTT~~~~~~~~HHHHHHHHHH~~EEEEEE~TTS~EEEEEEE~~~TT~~TTB~~STTSBTTTEEEETTTEEEEEEE~HHHHHHHTHHHHHHHHHHTT~~HHHHHHHHHHHHHHHHHHTT~~GGG~~EEEEEEETT~~EEEEESSS~~~EEEEETTEEEEE~~EES~~

T T N K P I V L S T W N F G L H A N V E A W K V L S K G G K A L D A V E K G V R L V E D D P T E R S V G Y G G R P D R D G R V T L D A C I M D E N Y N I G S V A C M E H I K N P I S V A R A V M E K T P H V M L V G D G A L E F A L S Q G F K K E N L L T A E S E K E W K E W L T I G M I A L D A Q G N L S G A C T T S D M A Y K M H G R V G D S P I I G A G L F V D N E I G A A T A T G H G E E V I R T V G T H L V V E L M N Q G R T P Q Q A C K E A V E R I V K I V N R R G K N L K D I Q V G F I A L N K K G E Y G A Y C I Q D G F N F A V H D Q K G N R L E T P G F A L K T T N K P I V L S T W N F G L H A N V E A W K V L S K G G K A L D A V E K G V R L V E D G R P D R D G R V T L D A C I M D E N Y N I G S V A C M E H I K N P I S V A R A V M E K T P H V M L V G D G A L E F A L S Q G F K K E N L L T A E S E K E W K E W L T I G M I A L D A Q G N L S G A C T T S D M A Y K M H G R V G D S P I I G A G L F V D N E I G A A T A T G H G E E V I R T V G T H L V V E L M N Q G R T P Q Q A C K E A V E R I V K I V N R R G K N L K D I Q V G F I A L N K K G E Y G A Y C I Q D G F N F A V H D Q K G N R L E T P G F A L K

AH

BS

2RA4

DALNVPSTCCFTFSSKKISLQRLKSYVITTSRCPQKAVIFRTKLGKEICADPKEKWVQNYMKHLGDALNVPSTCCFTFSSKKISLQRLKSYVITTSRCPQKAVIFRTKLGKEICADPKEKWVQNYMKHLG

~~~~~~EEE~SS~~SS~~~GGGEEEEEE~~TTSSS~~EEEEETTS~EEEE~TTSHHHHHHHHHH~~~~~~~EEE~SS~~SS~~~GGGEEEEEE~~TTSSS~~EEEEETTS~EEEE~TTSHHHHHHHHHH~

D A L N V P S T C C F T F S S K K I S L Q R L K S Y V I T T S R C P Q K A V I F R T K L G K E I C A D P K E K W V Q N Y M K H L G D A L N V P S T C C F T F S S K K I S L Q R L K S Y V I T T S R C P Q K A V I F R T K L G K E I C A D P K E K W V Q N Y M K H L G

UNSTRUCTURED

BS

4OBU

TEYILNSTQLEEAIKSFVHDFCAEKHEIHDQPVVVEAKEHQEDKIKQIKIPEKGRPVNEVVSEMMNEVYRYRGDANHPRFFSFVPGPASSVSWLGDIMTSAYNIHAGGSKLAPMVNCIEQEVLKWLAKQVGFTENPGGVFVSGGSMANITALTAARDNKLTDINLHLGTAYISDQTHSSVAKGLRIIGITDSRIRRIPTNSHFQMDTTKLEEAIETDKKSGYIPFVVIGTAGTTNTGSIDPLTEISALCKKHDMWFHIDGAYGASVLLSPKYKSLLTGTGLADSISWDAHKWLFQTYGCAMVLVKDIRNLFHSFHVNPEYLDIGMELTRPARGLKLWLTLQVLGSDLIGSAIEHGFQLAVWAEEALNPKKDWEIVSPAQMAMINFRYAPKDLTKEEQDILNEKISHRILESGYAAIFTTVLNGKTVLRICAIHPEATQEDMQHTIDLLDQYGREIYTEMKKATEYILNSTQLEEAIKSFVHDFCAEKHEIHDQPVVVEAKEHQEDKIKQIKIPEKGRPVNEVVSEMMNEVYRYRGDANHPRFFSFVPGPASSVSWLGDIMTSAYNIHAGGSKLAPMVNCIEQEVLKWLAKQVGFTENPGGVFVSGGSMANITALTAARDNKLTDINLHLGTAYISDQTHSSVAKGLRIIGITDSRIRRIPTNSHFQMDTTKLEEAIETDKKSGYIPFVVIGTAGTTNTGSIDPLTEISALCKKHDMWFHIDGAYGASVLLSPKYKSLLTGTGLADSISWDAHKWLFQTYGCAMVLVKDIRNLFHSFHVNPEYLDIGMELTRPARGLKLWLTLQVLGSDLIGSAIEHGFQLAVWAEEALNPKKDWEIVSPAQMAMINFRYAPKDLTKEEQDILNEKISHRILESGYAAIFTTVLNGKTVLRICAIHPEATQEDMQHTIDLLDQYGREIYTEMKKATEYILNSTQLEEAIKSFVHDFCAEKHEIHDQPVVVEAKEHQEDKIKQIKIPEKGRPVNEVVSEMMNEVYRYRGDANHPRFFSFVPGPASSVSWLGDIMTSAYNIHAGGSKLAPMVNCIEQEVLKWLAKQVGFTENPGGVFVSGGSMANITALTAARDNKLTDINLHLGTAYISDQTHSSVAKGLRIIGITDSRIRRIPTNSHFQMDTTKLEEAIETDKKSGYIPFVVIGTAGTTNTGSIDPLTEISALCKKHDMWFHIDGAYGASVLLSPKYKSLLTGTGLADSISWDAHKWLFQTYGCAMVLVKDIRNLFHSFHVNPEYLDIGMELTRPARGLKLWLTLQVLGSDLIGSAIEHGFQLAVWAEEALNPKKDWEIVSPAQMAMINFRYAPKDLTKEEQDILNEKISHRILESGYAAIFTTVLNGKTVLRICAIHPEATQEDMQHTIDLLDQYGREIYTEMKKATEYILNSTQLEEAIKSFVHDFCAEKHEIHDQPVVVEAKEHQEDKIKQIKIPEKGRPVNEVVSEMMNEVYRYRGDANHPRFFSFVPGPASSVSWLGDIMTSAYNIHAGGSKLAPMVNCIEQEVLKWLAKQVGFTENPGGVFVSGGSMANITALTAARDNKLTDINLHLGTAYISDQTHSSVAKGLRIIGITDSRIRRIPTNSHFQMDTTKLEEAIETDKKSGYIPFVVIGTAGTTNTGSIDPLTEISALCKKHDMWFHIDGAYGASVLLSPKYKSLLTGTGLADSISWDAHKWLFQTYGCAMVLVKDIRNLFHSFHVNPEYLDIGMELTRPARGLKLWLTLQVLGSDLIGSAIEHGFQLAVWAEEALNPKKDWEIVSPAQMAMINFRYAPKDLTKEEQDILNEKISHRILESGYAAIFTTVLNGKTVLRICAIHPEATQEDMQHTIDLLDQYGREIYTEMKKATEYILNSTQLEEAIKSFVHDFCAEKHEIHDQPVVVEAKEHQEDKIKQIKIPEKGRPVNEVVSEMMNEVYRYRGDANHPRFFSFVPGPASSVSWLGDIMTSAYNIHAGGSKLAPMVNCIEQEVLKWLAKQVGFTENPGGVFVSGGSMANITALTAARDNKLTDINLHLGTAYISDQTHSSVAKGLRIIGITDSRIRRIPTNSHFQMDTTKLEEAIETDKKSGYIPFVVIGTAGTTNTGSIDPLTEISALCKKHDMWFHIDGAYGASVLLSPKYKSLLTGTGLADSISWDAHKWLFQTYGCAMVLVKDIRNLFHSFHVNPEYLDIGMELTRPARGLKLWLTLQVLGSDLIGSAIEHGFQLAVWAEEALNPKKDWEIVSPAQMAMINFRYAPKDLTKEEQDILNEKISHRILESGYAAIFTTVLNGKTVLRICAIHPEATQEDMQHTIDLLDQYGREIYTEMKKATEYILNSTQLEEAIKSFVHDFCAEKHEIHDQPVVVEAKEHQEDKIKQIKIPEKGRPVNEVVSEMMNEVYRYRGDANHPRFFSFVPGPASSVSWLGDIMTSAYNIHAGGSKLAPMVNCIEQEVLKWLAKQVGFTENPGGVFVSGGSMANITALTAARDNKLTDINLHLGTAYISDQTHSSVAKGLRIIGITDSRIRRIPTNSHFQMDTTKLEEAIETDKKSGYIPFVVIGTAGTTNTGSIDPLTEISALCKKHDMWFHIDGAYGASVLLSPKYKSLLTGTGLADSISWDAHKWLFQTYGCAMVLVKDIRNLFHSFHVNPEYLDIGMELTRPARGLKLWLTLQVLGSDLIGSAIEHGFQLAVWAEEALNPKKDWEIVSPAQMAMINFRYAPKDLTKEEQDILNEKISHRILESGYAAIFTTVLNGKTVLRICAIHPEATQEDMQHTIDLLDQYGREIYTEMKKATEYILNSTQLEEAIKSFVHDFCAEKHEIHDQPVVVEAKEHQEDKIKQIKIPEKGRPVNEVVSEMMNEVYRYRGDANHPRFFSFVPGPASSVSWLGDIMTSAYNIHAGGSKLAPMVNCIEQEVLKWLAKQVGFTENPGGVFVSGGSMANITALTAARDNKLTDINLHLGTAYISDQTHSSVAKGLRIIGITDSRIRRIPTNSHFQMDTTKLEEAIETDKKSGYIPFVVIGTAGTTNTGSIDPLTEISALCKKHDMWFHIDGAYGASVLLSPKYKSLLTGTGLADSISWDAHKWLFQTYGCAMVLVKDIRNLFHSFHVNPEYLDIGMELTRPARGLKLWLTLQVLGSDLIGSAIEHGFQLAVWAEEALNPKKDWEIVSPAQMAMINFRYAPKDLTKEEQDILNEKISHRILESGYAAIFTTVLNGKTVLRICAIHPEATQEDMQHTIDLLDQYGREIYTEMKKATEYILNSTQLEEAIKSFVHDFCAEKHEIHDQPVVVEAKEHQEDKIKQIKIPEKGRPVNEVVSEMMNEVYRYRGDANHPRFFSFVPGPASSVSWLGDIMTSAYNIHAGGSKLAPMVNCIEQEVLKWLAKQVGFTENPGGVFVSGGSMANITALTAARDNKLTDINLHLGTAYISDQTHSSVAKGLRIIGITDSRIRRIPTNSHFQMDTTKLEEAIETDKKSGYIPFVVIGTAGTTNTGSIDPLTEISALCKKHDMWFHIDGAYGASVLLSPKYKSLLTGTGLADSISWDAHKWLFQTYGCAMVLVKDIRNLFHSFHVNPEYLDIGMELTRPARGLKLWLTLQVLGSDLIGSAIEHGFQLAVWAEEALNPKKDWEIVSPAQMAMINFRYAPKDLTKEEQDILNEKISHRILESGYAAIFTTVLNGKTVLRICAIHPEATQEDMQHTIDLLDQYGREIYTEMKKA

~TTSS~~HHHHHHHHHHHHHHHHHGGGSTTS~SB~~~~TTHHHHHHTS~~~SS~~~HHHHHHHHHHHTTTSSB~TTSTTB~~SSS~~~~HHHHHHHHHHHHHT~EEESSSS~HHHHHHHHHHHHHHHHHHT~~SB~EEEEESSHHHHHHHHHHHHHHHH~~TTTGGGEEEEEETTS~HHHHHHHHHTT~~GGGEEEE~B~TT~~B~HHHHHHHHHHHHHHT~EEEEEEEEBS~TTT~~B~~HHHHHHHHHHTT~EEEEE~TTGGGGGG~TTTGGGGTTGGGSSEEEEEHHHHS~~~S~~EEEEESBHHHHHHHH~~SSS~~~~SS~SEEE~HHHHHHHHHHHH~HHHHHHHHHHHHHHHHHHHHHHSSSTTEEEEEEEETTEEEEEE~~TTS~HHHHHHHHHHHHHHHHHHTS~B~EEEEETTEEEEEEE~~~TT~~HHHHHHHHHHHHHHHHHHHHT~~~~~TTSS~~HHHHHHHHHHHHHHHHHGGGSTTS~SB~~~~TTHHHHHHTS~~~SS~~~HHHHHHHHHHHTTTSSB~TTSTTB~~SSS~~~~HHHHHHHHHHHHHT~EEESSSS~HHHHHHHHHHHHHHHHHHT~~SB~EEEEESSHHHHHHHHHHHHHHHH~~TTTGGGEEEEEETTS~HHHHHHHHHTT~~GGGEEEE~B~TTS~B~HHHHHHHHHHHHHHT~EEEEEEEEBS~TTT~~B~~HHHHHHHHHHTT~EEEEE~TTGGGGGG~TTTGGGGTTGGGSSEEEEEHHHHS~~~S~~EEEEESBHHHHHHHH~~SSS~~~~SS~SEEE~HHHHHHHHHHHH~HHHHHHHHHHHHHHHHHHHHHHSSSTTEEEEEEEETTEEEEEE~~TTS~HHHHHHHHHHHHHHHHHHTS~B~EEEEETTEEEEEEE~~~TT~~HHHHHHHHHHHHHHHHHHHHT~~~~~TTSS~~HHHHHHHHHHHHHHHHHGGGSTTS~SB~~~~TTHHHHHHTS~~~SS~~~HHHHHHHHHHHTTTSSB~TTSTTB~~SSS~~~~HHHHHHHHHHHHHT~EEESSSSSHHHHHHHHHHHHHHHHHHT~~SB~EEEEESSHHHHHHHHHHHHHHHH~~TTTGGGEEEEEETTS~HHHHHHHHHTT~~GGGEEEE~B~TT~~B~HHHHHHHHHHHHHHT~EEEEEEEEBS~TTT~~B~~HHHHHHHHHHTT~EEEEE~TTGGGGGG~TTTGGGGTTGGGSSEEEEEHHHHS~~~S~~EEEEESBTHHHHHHH~~SSS~~~~SS~SEEE~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSTTEEEEEEEETTEEEEEE~~TTS~HHHHHHHHHHHHHHHHHHTS~B~EEEEETTEEEEEEE~~~TT~~HHHHHHHHHHHHHHHHHHHHT~~~~~TTSS~~HHHHHHHHHHHHHHHHHGGGSTTS~SB~~~~TTHHHHHHTS~~~SS~~~HHHHHHHHHHHTTTSSB~TTSTTB~~SSS~~~~HHHHHHHHHHHHHT~EEESSSSSHHHHHHHHHHHHHHHHHHT~~SB~EEEEESSHHHHHHHHHHHHHHHH~~TTTGGGEEEEEETTS~HHHHHHHHHTT~~GGGEEEE~B~TTS~B~HHHHHHHHHHHHHHT~EEEEEEEEBS~TTT~~B~~HHHHHHHHHHTT~EEEEE~TTGGGGGG~TTTGGGGTTGGGSSEEEEEHHHHS~~~S~~EEEEESBTHHHHHHH~~SSS~~~~SS~SEEE~THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSTTEEEEEEEETTEEEEEE~~TTS~HHHHHHHHHHHHHHHHHHTS~B~EEEEETTEEEEEEE~~~TT~~HHHHHHHHHHHHHHHHHHHHT~~~~~TTSS~~HHHHHHHHHHHHHHHHHGGGSTTS~SB~~~~TTHHHHHHTS~~~SS~~~HHHHHHHHHHHTTTSSB~TTSTTB~~SSS~~~~HHHHHHHHHHHHHT~EEESSSSSHHHHHHHHHHHHHHHHHHT~~SB~EEEEESSHHHHHHHHHHHHHHHH~~TTTGGGEEEEEETTS~HHHHHHHHHTT~~GGGEEEE~B~TT~~B~HHHHHHHHHHHHHHT~EEEEEEEEBS~TTT~~B~~HHHHHHHHHHTT~EEEEE~TTGGGGGG~TTTGGGGTTGGGSSEEEEEHHHHS~~~S~~EEEEESBTHHHHHHH~~SSS~~~~~S~SEEE~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSTTEEEEEEEETTEEEEEE~~TTS~HHHHHHHHHHHHHHHHHHTS~B~EEEEETTEEEEEEE~~~TT~~HHHHHHHHHHHHHHHHHHHHT~~~~~TTSS~~HHHHHHHHHHHHHHHHHGGGSTTS~SB~~~~TTHHHHHHTS~~~SS~~~HHHHHHHHHHHTTTSSB~TTSTTB~~SSS~~~~HHHHHHHHHHHHHT~EEESSSSSHHHHHHHHHHHHHHHHHHT~~SB~EEEEESSHHHHHHHHHHHHHHHH~~TTTGGGEEEEEETTS~HHHHHHHHHTT~~GGGEEEE~B~TT~~B~HHHHHHHHHHHHHHT~EEEEEEEEBS~TTT~~B~~HHHHHHHHHHTT~EEEEE~TTGGGGGG~TTTGGGGTTGGGSSEEEEEHHHHS~~~S~~EEEEESBTHHHHHHH~~SSS~~~~SS~SEEE~THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSTTEEEEEEEETTEEEEEE~~TTS~HHHHHHHHHHHHHHHHHHTS~B~EEEEETTEEEEEEE~~~TT~~HHHHHHHHHHHHHHHHHHHHT~~~~~TTSS~~HHHHHHHHHHHHHHHHHGGGSTTS~SB~~~~TTHHHHHHTS~~~SS~~~HHHHHHHHHHHTTTSSB~TTSTTB~~SSS~~~~HHHHHHHHHHHHHT~EEESSSSSHHHHHHHHHHHHHHHHHHT~~SB~EEEEESSHHHHHHHHHHHHHHHH~~TTTGGGEEEEEETTS~HHHHHHHHHTT~~GGGEEEE~B~TT~~B~HHHHHHHHHHHHHHT~EEEEEEEEBS~TTT~~B~~HHHHHHHHHHTT~EEEEE~TTGGGGGG~TTTGGGGTTGGGSSEEEEEHHHHS~~~S~~EEEEESBTHHHHHHH~~SSS~~~~SS~SEEE~THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSTTEEEEEEEETTEEEEEE~~TTS~HHHHHHHHHHHHHHHHHHTS~B~EEEEETTEEEEEEE~~~TT~~HHHHHHHHHHHHHHHHHHHHT~~~~~TTSS~~HHHHHHHHHHHHHHHHHGGGSTTS~SB~~~~TTHHHHHHTS~~~SS~~~HHHHHHHHHHHTTTSSB~TTSTTB~~SSS~~~~HHHHHHHHHHHHHT~EEESSSSSHHHHHHHHHHHHHHHHHHT~~SB~EEEEESSHHHHHHHHHHHHHHHH~~TTTGGGEEEEEETTS~HHHHHHHHHTT~~GGGEEEE~B~TT~~B~HHHHHHHHHHHHHHT~EEEEEEEEBS~TTT~~B~~HHHHHHHHHHTT~EEEEE~TTGGGGGG~TTTGGGGTTGGGSSEEEEEHHHHS~~~S~~EEEEESBHHHHHHHH~~SSS~~~~SS~SEEE~THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSTTEEEEEEEETTEEEEEE~~TTS~HHHHHHHHHHHHHHHHHHTS~B~EEEEETTEEEEEEE~~~TT~~HHHHHHHHHHHHHHHHHHHHT~~~~

T E Y I L N S T Q L E E A I K S F V H D F C A E K H E I H D Q P V V V E A K E H Q E D K I K Q I K I P E K G R P V N E V V S E M M N E V Y R Y R G D A N H P R F F S F V P G P A S S V S W L G D I M T S A Y N I H A G G S K L A P M V N C I E Q E V L K W L A K Q V G F T E N P G G V F V S G G S M A N I T A L T A A R D N K L T D I N L H L G T A Y I S D Q T H S S V A K G L R I I G I T D S R I R R I P T N S H F Q M D T T K L E E A I E T D K K S G Y I P F V V I G T A G T T N T G S I D P L T E I S A L C K K H D M W F H I D G A Y G A S V L L S P K Y K S L L T G T G L A D S I S W D A H K W L F Q T Y G C A M V L V K D I R N L F H S F H V N P E Y L D I G M E L T R P A R G L K L W L T L Q V L G S D L I G S A I E H G F Q L A V W A E E A L N P K K D W E I V S P A Q M A M I N F R Y A P K D L T K E E Q D I L N E K I S H R I L E S G Y A A I F T T V L N G K T V L R I C A I H P E A T Q E D M Q H T I D L L D Q Y G R E I Y T E M K K A T E Y I L N S T Q L E E A I K S F V H D F C A E K H E I H D Q P V V V E A K E H Q E D K I K Q I K I P E K G R P V N E V V S E M M N E V Y R Y R G D A N H P R F F S F V P G P A S S V S W L G D I M T S A Y N I H A G G S K L A P M V N C I E Q E V L K W L A K Q V G F T E N P G G V F V S G G S M A N I T A L T A A R D N K L T D I N L H L G T A Y I S D Q T H S S V A K G L R I I G I T D S R I R R I P T N S H F Q M D T T K L E E A I E T D K K S G Y I P F V V I G T A G T T N T G S I D P L T E I S A L C K K H D M W F H I D G A Y G A S V L L S P K Y K S L L T G T G L A D S I S W D A H K W L F Q T Y G C A M V L V K D I R N L F H S F H V N P E Y L D I G M E L T R P A R G L K L W L T L Q V L G S D L I G S A I E H G F Q L A V W A E E A L N P K K D W E I V S P A Q M A M I N F R Y A P K D L T K E E Q D I L N E K I S H R I L E S G Y A A I F T T V L N G K T V L R I C A I H P E A T Q E D M Q H T I D L L D Q Y G R E I Y T E M K K A T E Y I L N S T Q L E E A I K S F V H D F C A E K H E I H D Q P V V V E A K E H Q E D K I K Q I K I P E K G R P V N E V V S E M M N E V Y R Y R G D A N H P R F F S F V P G P A S S V S W L G D I M T S A Y N I H A G G S K L A P M V N C I E Q E V L K W L A K Q V G F T E N P G G V F V S G G S M A N I T A L T A A R D N K L T D I N L H L G T A Y I S D Q T H S S V A K G L R I I G I T D S R I R R I P T N S H F Q M D T T K L E E A I E T D K K S G Y I P F V V I G T A G T T N T G S I D P L T E I S A L C K K H D M W F H I D G A Y G A S V L L S P K Y K S L L T G T G L A D S I S W D A H K W L F Q T Y G C A M V L V K D I R N L F H S F H V N P E Y L D I G M E L T R P A R G L K L W L T L Q V L G S D L I G S A I E H G F Q L A V W A E E A L N P K K D W E I V S P A Q M A M I N F R Y A P K D L T K E E Q D I L N E K I S H R I L E S G Y A A I F T T V L N G K T V L R I C A I H P E A T Q E D M Q H T I D L L D Q Y G R E I Y T E M K K A T E Y I L N S T Q L E E A I K S F V H D F C A E K H E I H D Q P V V V E A K E H Q E D K I K Q I K I P E K G R P V N E V V S E M M N E V Y R Y R G D A N H P R F F S F V P G P A S S V S W L G D I M T S A Y N I H A G G S K L A P M V N C I E Q E V L K W L A K Q V G F T E N P G G V F V S G G S M A N I T A L T A A R D N K L T D I N L H L G T A Y I S D Q T H S S V A K G L R I I G I T D S R I R R I P T N S H F Q M D T T K L E E A I E T D K K S G Y I P F V V I G T A G T T N T G S I D P L T E I S A L C K K H D M W F H I D G A Y G A S V L L S P K Y K S L L T G T G L A D S I S W D A H K W L F Q T Y G C A M V L V K D I R N L F H S F H V N P E Y L D I G M E L T R P A R G L K L W L T L Q V L G S D L I G S A I E H G F Q L A V W A E E A L N P K K D W E I V S P A Q M A M I N F R Y A P K D L T K E E Q D I L N E K I S H R I L E S G Y A A I F T T V L N G K T V L R I C A I H P E A T Q E D M Q H T I D L L D Q Y G R E I Y T E M K K A T E Y I L N S T Q L E E A I K S F V H D F C A E K H E I H D Q P V V V E A K E H Q E D K I K Q I K I P E K G R P V N E V V S E M M N E V Y R Y R G D A N H P R F F S F V P G P A S S V S W L G D I M T S A Y N I H A G G S K L A P M V N C I E Q E V L K W L A K Q V G F T E N P G G V F V S G G S M A N I T A L T A A R D N K L T D I N L H L G T A Y I S D Q T H S S V A K G L R I I G I T D S R I R R I P T N S H F Q M D T T K L E E A I E T D K K S G Y I P F V V I G T A G T T N T G S I D P L T E I S A L C K K H D M W F H I D G A Y G A S V L L S P K Y K S L L T G T G L A D S I S W D A H K W L F Q T Y G C A M V L V K D I R N L F H S F H V N P E Y L D I G M E L T R P A R G L K L W L T L Q V L G S D L I G S A I E H G F Q L A V W A E E A L N P K K D W E I V S P A Q M A M I N F R Y A P K D L T K E E Q D I L N E K I S H R I L E S G Y A A I F T T V L N G K T V L R I C A I H P E A T Q E D M Q H T I D L L D Q Y G R E I Y T E M K K A T E Y I L N S T Q L E E A I K S F V H D F C A E K H E I H D Q P V V V E A K E H Q E D K I K Q I K I P E K G R P V N E V V S E M M N E V Y R Y R G D A N H P R F F S F V P G P A S S V S W L G D I M T S A Y N I H A G G S K L A P M V N C I E Q E V L K W L A K Q V G F T E N P G G V F V S G G S M A N I T A L T A A R D N K L T D I N L H L G T A Y I S D Q T H S S V A K G L R I I G I T D S R I R R I P T N S H F Q M D T T K L E E A I E T D K K S G Y I P F V V I G T A G T T N T G S I D P L T E I S A L C K K H D M W F H I D G A Y G A S V L L S P K Y K S L L T G T G L A D S I S W D A H K W L F Q T Y G C A M V L V K D I R N L F H S F H V N P E Y L D I G M E L T R P A R G L K L W L T L Q V L G S D L I G S A I E H G F Q L A V W A E E A L N P K K D W E I V S P A Q M A M I N F R Y A P K D L T K E E Q D I L N E K I S H R I L E S G Y A A I F T T V L N G K T V L R I C A I H P E A T Q E D M Q H T I D L L D Q Y G R E I Y T E M K K A T E Y I L N S T Q L E E A I K S F V H D F C A E K H E I H D Q P V V V E A K E H Q E D K I K Q I K I P E K G R P V N E V V S E M M N E V Y R Y R G D A N H P R F F S F V P G P A S S V S W L G D I M T S A Y N I H A G G S K L A P M V N C I E Q E V L K W L A K Q V G F T E N P G G V F V S G G S M A N I T A L T A A R D N K L T D I N L H L G T A Y I S D Q T H S S V A K G L R I I G I T D S R I R R I P T N S H F Q M D T T K L E E A I E T D K K S G Y I P F V V I G T A G T T N T G S I D P L T E I S A L C K K H D M W F H I D G A Y G A S V L L S P K Y K S L L T G T G L A D S I S W D A H K W L F Q T Y G C A M V L V K D I R N L F H S F H V N P E Y L D I G M E L T R P A R G L K L W L T L Q V L G S D L I G S A I E H G F Q L A V W A E E A L N P K K D W E I V S P A Q M A M I N F R Y A P K D L T K E E Q D I L N E K I S H R I L E S G Y A A I F T T V L N G K T V L R I C A I H P E A T Q E D M Q H T I D L L D Q Y G R E I Y T E M K K A T E Y I L N S T Q L E E A I K S F V H D F C A E K H E I H D Q P V V V E A K E H Q E D K I K Q I K I P E K G R P V N E V V S E M M N E V Y R Y R G D A N H P R F F S F V P G P A S S V S W L G D I M T S A Y N I H A G G S K L A P M V N C I E Q E V L K W L A K Q V G F T E N P G G V F V S G G S M A N I T A L T A A R D N K L T D I N L H L G T A Y I S D Q T H S S V A K G L R I I G I T D S R I R R I P T N S H F Q M D T T K L E E A I E T D K K S G Y I P F V V I G T A G T T N T G S I D P L T E I S A L C K K H D M W F H I D G A Y G A S V L L S P K Y K S L L T G T G L A D S I S W D A H K W L F Q T Y G C A M V L V K D I R N L F H S F H V N P E Y L D I G M E L T R P A R G L K L W L T L Q V L G S D L I G S A I E H G F Q L A V W A E E A L N P K K D W E I V S P A Q M A M I N F R Y A P K D L T K E E Q D I L N E K I S H R I L E S G Y A A I F T T V L N G K T V L R I C A I H P E A T Q E D M Q H T I D L L D Q Y G R E I Y T E M K K A

AH

UNSTRUCTURED

4EXM

PAFLFSGSTLSSYRPNFEANSITIALPHYVDLPGRSNFKLMYIMGFPIDTEMEKDSEYSNKIRQESKISKTEGTVSYEQKITVETGQEKDGVKVYRVMVLEGTIAESIEHLDKKENEDILNNNRNRIVLADNTVINFDNISQLKEFLRRSVNIVIFEMLRIDERLRLKIYKDTEGYYTIGIGHLVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSIWYNQTPNRAKRVITTFRTGTWDAYKNPAFLFSGSTLSSYRPNFEANSITIALPHYVDLPGRSNFKLMYIMGFPIDTEMEKDSEYSNKIRQESKISKTEGTVSYEQKITVETGQEKDGVKVYRVMVLEGTIAESIEHLDKKENEDILNNNRNRIVLADNTVINFDNISQLKEFLRRSVNIVIFEMLRIDERLRLKIYKDTEGYYTIGIGHLGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSIWYNQTPNRAKRVITTFRTGTWDAYKFQSMSDTMVVNGSGGVPAFLFSGSTLSSYRPNFEANSITIALPHYVDLPGRSNFKLMYIMGFPIDTEMEKDSEYSNKIRQESKISKTEGTVSYEQKITVETGQEKDGVKVYRVMVLEGTIAESIEHLDKKENEDILNNNRNRIVLADNTVINFDNISQLKEFLRRSVNIVIFEMLRIDERLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSIWYNQTPNRAKRVITTFRTGTWDAYKNFQSMSDTMVVNGSGGVPAFLFSGSTLSSYRPNFEANSITIALPHYVDLPGRSNFKLMYIMGFPIDTEMEKDSEYSNKIRQESKISKTEGTVSYEQKITVETGQEKDGVKVYRVMVLEGTIAESIEHLDKKENEDILNNNRNRIVLADNTVINFDNISQLKEFLRRSVNIVIFEMLRIDERLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSIWYNQTPNRAKRVITTFRTGTWDAYKN

~TTTT~S~EEES~~~SS~SSSGGGGS~EEEE~TT~SS~EEEEETTEEEEEEESS~~SS~B~~~~B~~S~TTT~~~~TTS~EEEEEEEEETTEEEEEEEEEEE~HHHHHHHTT~GGGHHHHHSSEEEEE~TTS~EEEESSHHHHHHHHHHHHSHHHHHHHHHHT~EEEEEEE~TTS~EEEEETB~~~~HHHHHHHHHHHHHHHHHHHHTSTTTHHHHHTS~HHHHHHHHHHHHHHHHHHHHT~HHHHHHHTTT~~SHHHHTTTTSHHHHHSHHHHHHHHHHHHHSSSTTT~~~TTTT~S~EEES~~~SS~SSSGGGGS~EEEE~TT~SS~EEEEETTEEEEEEESS~~SSSB~~~~B~~S~TTT~~~~TTS~EEEEEEEEETTEEEEEEEEEEE~HHHHHHHTT~GGGHHHHHSSEEEEE~TTS~EEEESSHHHHHHHHHHHHTHHHHHHHHHHH~~EEEEEE~TTS~EEEETTB~~B~~HHHHHHHHHHHHHHHHHHHHT~TTTHHHHHTS~HHHHHHHHHHHHHHHHHHHHT~HHHHHTTSSS~SSHHHHHTTTSHHHHHSHHHHHHHHHHHHHSSSTTT~~EEEEE~S~~~STT~~~SSTT~S~~EESS~~~~~S~GGGTTS~EEEE~TT~SS~EEEEETTEEEEEEESS~~SSSEE~~~B~SS~SSS~~~~TTS~EEEEEEEEETTEEEEEEEEEEE~HHHHHHHHT~GGGHHHHHSSEEEEE~TTS~EEEESSHHHHHHHHHHHHHHHHHHHHHHHH~~EEEEEE~SSS~EEEETTEE~~S~S~HHHHHHHHHHHHTS~~TTB~~HHHHHHHHHHHHHHHHHHHHT~TTHHHHHHTS~HHHHHHHHHHHHHHHHHHHHTTTHHHHHHHTT~HHHHHHHHHSSHHHHH~HHHHHHHHHHHHSSSSTT~~~~EEEEE~S~~~STT~~~TTTT~S~~EESS~~~~~S~GGGTTS~EEEE~TT~SS~EEEEETTEEEEEEESS~~SSSEE~~~B~SS~SSS~~~~TTS~EEEEEEEEETTEEEEEEEEEEE~HHHHHHHHT~GGGHHHHHSSEEEEE~TTS~EEEESSHHHHHHHHHHHHHHHHHHHHHHHH~~EEEEEE~SSS~EEEETTEE~~S~S~HHHHHHHHHHHHTS~~TTB~~HHHHHHHHHHHHHHHHHHHHT~TTHHHHHHTS~HHHHHHHHHHHHHHHHHHHHTTTHHHHHHHTT~HHHHHHHHHSSHHHHHSHHHHHHHHHHHHSSSSTT~~~

P A F L F S G S T L S S Y R P N F E A N S I T I A L P H Y V D L P G R S N F K L M Y I M G F P I D T E M E K D S E Y S N K I R Q E S K I S K T E G T V S Y E Q K I T V E T G Q E K D G V K V Y R V M V L E G T I A E S I E H L D K K E N E D I L N N N R N R I V L A D N T V I N F D N I S Q L K E F L R R S V N I V I F E M L R I D E R L R L K I Y K D T E G Y Y T I G I G H L V I T K D E A E K L F N Q D V D A A V R G I L R N A K L K P V Y D S L D A V R R A A L I N M V F Q M G E T G V A G F T N S L R M L Q Q K R W D E A A V N L A K S I W Y N Q T P N R A K R V I T T F R T G T W D A Y K N P A F L F S G S T L S S Y R P N F E A N S I T I A L P H Y V D L P G R S N F K L M Y I M G F P I D T E M E K D S E Y S N K I R Q E S K I S K T E G T V S Y E Q K I T V E T G Q E K D G V K V Y R V M V L E G T I A E S I E H L D K K E N E D I L N N N R N R I V L A D N T V I N F D N I S Q L K E F L R R S V N I V I F E M L R I D E R L R L K I Y K D T E G Y Y T I G I G H L G V I T K D E A E K L F N Q D V D A A V R G I L R N A K L K P V Y D S L D A V R R A A L I N M V F Q M G E T G V A G F T N S L R M L Q Q K R W D E A A V N L A K S I W Y N Q T P N R A K R V I T T F R T G T W D A Y K F Q S M S D T M V V N G S G G V P A F L F S G S T L S S Y R P N F E A N S I T I A L P H Y V D L P G R S N F K L M Y I M G F P I D T E M E K D S E Y S N K I R Q E S K I S K T E G T V S Y E Q K I T V E T G Q E K D G V K V Y R V M V L E G T I A E S I E H L D K K E N E D I L N N N R N R I V L A D N T V I N F D N I S Q L K E F L R R S V N I V I F E M L R I D E R L R L K I Y K D T E G Y Y T I G I G H L L T K S P S L N A A K S E L D K A I G R N T N G V I T K D E A E K L F N Q D V D A A V R G I L R N A K L K P V Y D S L D A V R R A A L I N M V F Q M G E T G V A G F T N S L R M L Q Q K R W D E A A V N L A K S I W Y N Q T P N R A K R V I T T F R T G T W D A Y K N F Q S M S D T M V V N G S G G V P A F L F S G S T L S S Y R P N F E A N S I T I A L P H Y V D L P G R S N F K L M Y I M G F P I D T E M E K D S E Y S N K I R Q E S K I S K T E G T V S Y E Q K I T V E T G Q E K D G V K V Y R V M V L E G T I A E S I E H L D K K E N E D I L N N N R N R I V L A D N T V I N F D N I S Q L K E F L R R S V N I V I F E M L R I D E R L R L K I Y K D T E G Y Y T I G I G H L L T K S P S L N A A K S E L D K A I G R N T N G V I T K D E A E K L F N Q D V D A A V R G I L R N A K L K P V Y D S L D A V R R A A L I N M V F Q M G E T G V A G F T N S L R M L Q Q K R W D E A A V N L A K S I W Y N Q T P N R A K R V I T T F R T G T W D A Y K N

AH

BS

5V8H

GASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTGSYYEHVKISAPNEFDVMFKLEVPRIQLEEYSNTRAYYFVKFKPLSQFLEGEILSASKMLSKFRKIIKEEINDIKDTDVIMKRKRAVTLLISEKISVDITLALESKSSWPASTQEGLRIQNWLSAKVRKQLRLKPFYLVPKHAKEFQEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKDCLKLMKYLLEQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNCVTYFLQCLRTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERNNEFPVFDEGASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTGSYYEHVKISAPNEFDVMFKLEVPRIQLEEYSNTRAYYFVKFKKENPLSQFLEGEILSASKMLSKFRKIIKEEINDTDVIMKRKAVTLLISEKISVDITLALESKSSWPASTQEGLRIQNWLSAKVRKQLRLKPFYLVPKHAKGFQEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKDCLKLMKYLLEQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNCVTYFLQCLRTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERNNEFPVFD

~~HHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHHTTSSTTTTEEEE~~STTTTT~~~S~TTEEEEEEEEE~SS~EEEESTT~SSEEEEE~~~~GGGBSSSBB~HHHHHHHHHHHHHHHHHH~~SS~EEEE~~~~EEEEETTTEEEEEEEEEEE~S~~~GGGTT~~~~TTTT~HHHHHHHHTS~EEEEE~~B~~~BTT~EEEE~HHHHHHHHHS~~SBTTTTSSGGG~B~HHHHHHHHHHHHHHHHHHTTTT~GGGG~~HHHHHHHHHHHHHH~~SGGGGBGGGHHHHHHHHHHHHHHHHHHT~~B~SS~TT~BTT~TTTS~HHHHHHHHHHHHHHHHTT~HHHH~~~HHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHHHTTSSTTTTEEE~~~STTTTT~~~S~TTEEEEEEEEE~SSEEEEE~TT~SSEEEEEE~~~STTGGGBSSSSB~HHHHHHHHHHHHHHHHH~~~EEEE~~~EEEEETTTEEEEEEEEEEE~S~~~GGGTT~~~~IIIIIHHHHHHHHTS~EEEEE~~B~~~BTT~EEEE~HHHHHHHHHS~~SBTTTTSSGGG~B~HHHHHHHHHHHHHHHHHHTTT~TTGGG~~HHHHHHHHHHHHHH~~SGGGGBGGGHHHHHHHHHHHHHHHHHTT~~B~SS~TT~BTT~TTTS~HHHHHHHHHHHHHHHHTT~TTT~

G A S K L R A V L E K L K L S R D D I S T A A G M V K G V V D H L L L R L K C D S A F R G V G L L N T G S Y Y E H V K I S A P N E F D V M F K L E V P R I Q L E E Y S N T R A Y Y F V K F K P L S Q F L E G E I L S A S K M L S K F R K I I K E E I N D I K D T D V I M K R K R A V T L L I S E K I S V D I T L A L E S K S S W P A S T Q E G L R I Q N W L S A K V R K Q L R L K P F Y L V P K H A K E F Q E E T W R L S F S H I E K E I L N N H G K S K T C C E N K E E K C C R K D C L K L M K Y L L E Q L K E R F K D K K H L D K F S S Y H V K T A F F H V C T Q N P Q D S Q W D R K D L G L C F D N C V T Y F L Q C L R T E K L E N Y F I P E F N L F S S N L I D K R S K E F L T K Q I E Y E R N N E F P V F D E G A S K L R A V L E K L K L S R D D I S T A A G M V K G V V D H L L L R L K C D S A F R G V G L L N T G S Y Y E H V K I S A P N E F D V M F K L E V P R I Q L E E Y S N T R A Y Y F V K F K K E N P L S Q F L E G E I L S A S K M L S K F R K I I K E E I N D T D V I M K R K A V T L L I S E K I S V D I T L A L E S K S S W P A S T Q E G L R I Q N W L S A K V R K Q L R L K P F Y L V P K H A K G F Q E E T W R L S F S H I E K E I L N N H G K S K T C C E N K E E K C C R K D C L K L M K Y L L E Q L K E R F K D K K H L D K F S S Y H V K T A F F H V C T Q N P Q D S Q W D R K D L G L C F D N C V T Y F L Q C L R T E K L E N Y F I P E F N L F S S N L I D K R S K E F L T K Q I E Y E R N N E F P V F D

AH

UNSTRUCTURED

4JG4

AHLKKRNRLKKNEDFQKVFKHGTSVANRQFVLYTLDQAENDELRVGLSVSKKIGNAVMRNRIKRLIRQAFLEEKERLKEKDYIIIARKAASQLTYEETKKSLQHLWRKSSLYKK

~~~~GGGB~~~HHHHHHHHHHSEEEE~SSEEEEEE~~SS~SS~EEEEEE~TTS~~HHHHHHHHHHHHHHHHHHTTTB~S~EEEEEE~GGGGG~~HHHHHHHHHHHHHHTT~B~~

A H L K K R N R L K K N E D F Q K V F K H G T S V A N R Q F V L Y T L D Q A E N D E L R V G L S V S K K I G N A V M R N R I K R L I R Q A F L E E K E R L K E K D Y I I I A R K A A S Q L T Y E E T K K S L Q H L W R K S S L Y K K

AH

UNSTRUCTURED

5V21

PSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIRAAGGKAPATGGVMKPHRYRP

~EEEGGGGG~HHHHHHHHHTTSS~~~~EE~SS~EESS~~~~~~~~~~HHHHHTT~~TT~TT~HHHHTTB~~~TT~TTGGG~SS~HHHHT~~~~EEEEE~SSS~EEEEESS~B~TT~EEEE~~EEEE~HHHHHHHHHHHHHHT~SS~~EEEEETTEEEEEEEEE~GGGG~EE~SS~SEEEEEEEETTEEEEEEEESS~B~TT~EEEE~~~~EE~SSS~~B~~~~~TT~~SBTT~S~~~~HHHHTT~~~SS~EEE~~~~~~~

P S C V M D D F R D P Q R W K E C A K Q G K M P C Y F D L I E E N V Y L T E R Q C E C T P L S K D E R A Q G E I A C G E D C L N R L L M I E C S S R C P N G D Y C S N R R F Q R K Q H A D V E V I L T E K K G W G L R A A K D L P S N T F V L E Y C G E V L D H K E F K A R V K E Y A R N K N I H Y Y F M A L K N D E I I D A T Q K G N C S R F M N H S C E P N C E T Q K W T V N G Q L R V G F F T T K L V P S G S E L T F D Y Q F Q R Y G K E A Q K C F C G S A N C R G Y L G G E N R V S I R A A G G K A P A T G G V M K P H R Y R P

UNSTRUCTURED

BS

5TYN

FNVSLMEKLKWKIKCIENKFLNYRLTTNETVVAETEYGKVKGVKRLTVYDDSYYSFEGIPYAQPPVGELRFKAPQRPTPWAGVRDCCNHKDKSVQVDFITGKVCGSEDCLYLSVYTNNLNPETKRPVLVYIHGGGFIIGENHRDMYGPDYFIKKDVVLINIQYRLGALGFLSLNSEDLNVPGNAGLKDQVMALRWIKNNCANFGGNPDNITVFGESAGAASTHYMMLTEQTRGLFHRGILMSGNAICPWANTQCQHRAFTLAKLAGYKGEDNDKDVLEFLMKAKPQDLIKLEEKVLTLEERTNKVMFPFGPTVEPYQTADCVLPKHPREMVKTAWGNSIPTMMGNTSYEGLFFTSILKQMPLLVKELETCVNFVPSELADAERTAPETLEMGAKIKKAHVTGETPTADNFMDLCSHFYFWFPMHRLLQLRFNHTSGTPVYLYRFDFDSEDLINPYRIMRSGRGVKGVSHTDELTYFFWNQLAKRMPKESREYKTIERMTGIWTQFATTGNPYSNEIEGMENVSWDPIEKSDEVYKCLNISDELKMIDVPEMGKIKQWESMFEKHRDLF

~~~~HHHHHHHHHHHHHHHHHHHHTEEEEEEEE~~TT~EEEEEEEE~TTS~EEEEEEEEESS~~~~GGGTTS~~~~~~~~SSEEE~BS~~~~BSEE~TTT~SEE~BS~~~EEEEEES~SS~SS~EEEEEEE~~STTTS~~~~TTTSBTTTGGGSS~EEEEE~~~~HHHHH~~~S~GGG~~~S~HHHHHHHHHHHHHHHHGGGGTEEEEEEEEEEETHHHHHHHHHHH~GGGTTS~SEEEEES~~TTSGGG~~~~TTHHHHHHHHTT~~S~S~HHHHHHHHHHS~HHHHHHHGGG~S~HHHHHTT~~~SS~~~~~SS~~TT~S~SS~HHHHHTT~GGGGS~EEEEEETTGGGGGHHHHHH~GGGGGGGGT~GGGS~TTTS~TTS~SHHHHHHHHHHHHHH~~SSS~~HHHHHHHHHHHHTHHHHHHHHHHHTTS~~~~~EEEEEE~~~~SSS~~THHHHTT~TT~~S~~TTGGGGGTSB~TT~~~~~TTSHHHHHHHHHHHHHHHHHHHS~~~~TTSTT~TT~~~~~~~TT~SS~EEEEESSSEEEEE~TTHHHHHHHHGGGTT~GGG~

F N V S L M E K L K W K I K C I E N K F L N Y R L T T N E T V V A E T E Y G K V K G V K R L T V Y D D S Y Y S F E G I P Y A Q P P V G E L R F K A P Q R P T P W A G V R D C C N H K D K S V Q V D F I T G K V C G S E D C L Y L S V Y T N N L N P E T K R P V L V Y I H G G G F I I G E N H R D M Y G P D Y F I K K D V V L I N I Q Y R L G A L G F L S L N S E D L N V P G N A G L K D Q V M A L R W I K N N C A N F G G N P D N I T V F G E S A G A A S T H Y M M L T E Q T R G L F H R G I L M S G N A I C P W A N T Q C Q H R A F T L A K L A G Y K G E D N D K D V L E F L M K A K P Q D L I K L E E K V L T L E E R T N K V M F P F G P T V E P Y Q T A D C V L P K H P R E M V K T A W G N S I P T M M G N T S Y E G L F F T S I L K Q M P L L V K E L E T C V N F V P S E L A D A E R T A P E T L E M G A K I K K A H V T G E T P T A D N F M D L C S H F Y F W F P M H R L L Q L R F N H T S G T P V Y L Y R F D F D S E D L I N P Y R I M R S G R G V K G V S H T D E L T Y F F W N Q L A K R M P K E S R E Y K T I E R M T G I W T Q F A T T G N P Y S N E I E G M E N V S W D P I E K S D E V Y K C L N I S D E L K M I D V P E M G K I K Q W E S M F E K H R D L F

AH

UNSTRUCTURED

4DKK

GSKATVTAMIARELLYGGTSPTAETILKNNISGPLTRPSEQLDYLSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELD

~~HHHHHHHHHHHHHHHS~~HHHHHHH~~S~~~~~~SHHHHHHHHHHHH~~~EEEEEE~~~TTS~EEEEEEE~SSS~EEEEEEESSHHHHHHHHHHHHHHHHTT~~

G S K A T V T A M I A R E L L Y G G T S P T A E T I L K N N I S G P L T R P S E Q L D Y L S R V Q G F Q V E Y K D F P K N N K N E F V S L I N C S S Q P P L I S H G I G K D V E S C H D M A A L N I L K L L S E L D

AH

UNSTRUCTURED

1DWW

QYVRIKNWGSGEILHDTLHHKATSDFTCKSKSCLGSIMNPKSLTRGPRDKPTPLEELLPHAIEFINQYYGSFKEAKIEEHLARLEAVTKEIETTGTYQLTLDELIFATKMAWRNAPRCIGRIQWSNLQVFDARNCSTAQEMFQHICRHILYATNNGNIRSAITVFPQRSDGKHDFRLWNSQLIRYAGYQMPDGTIRGDAATLEFTQLCIDLGWKPRYGRFDVLPLVLQADGQDPEVFEIPPDLVLEVTMEHPKYEWFQELGLKWYALPAVANMLLEVGGLEFPACPFNGWYMGTEIGVRDFCDTQRYNILEEVGRRMGLETHTLASLWKDRAVTEINVAVLHSFQKQNVTIMDHHTASESFMKHMQNEYRARGGCPADWIWLVPPVSGSITPVFHQEMLNYVLSPFYYYQIEPWKTHIWQQYVRIKNWGSGEILHDTLHHKATSDFTCKSKSCLGSIMNPKSLTRGPRDKPTPLEELLPHAIEFINQYYGSFKEAKIEEHLARLEAVTKEIETTGTYQLTLDELIFATKMAWRNAPRCIGRIQWSNLQVFDARNCSTAQEMFQHICRHILYATNNGNIRSAITVFPQRSDGKHDFRLWNSQLIRYAGYQMPDGTIRGDAATLEFTQLCIDLGWKPRYGRFDVLPLVLQADGQDPEVFEIPPDLVLEVTMEHPKYEWFQELGLKWYALPAVANMLLEVGGLEFPACPFNGWYMGTEIGVRDFCDTQRYNILEEVGRRMGLETHTLASLWKDRAVTEINVAVLHSFQKQNVTIMDHHTASESFMKHMQNEYRARGGCPADWIWLVPPVSGSITPVFHQEMLNYVLSPFYYYQIEPWKTHIWQ

~~EEEEBTTT~~EEEE~GGGG~~S~~S~~SS~~~TT~SS~GGGB~~~~SS~~~HHHHHHHHHHHHHHHHTSSTT~~HHHHHHHHHHHHHHHHHHSS~~~~HHHHHHHHHHHHHT~TT~TTGGGTT~~EEEE~TT~~SHHHHHHHHHHHHHHHHGGGS~~~EEEE~~~~SSSSS~~EE~SSBSS~B~EE~~TTS~~EE~GGGHHHHHHHHHTT~~~~~SSS~B~~EEEE~TT~~~EEE~~~TTT~~EEE~~~SS~TTGGGG~~EEES~~EE~S~EEEETTEEES~~~EE~~~BHHHHHTTTTT~TTTT~~HHHHHHTTT~~TT~GGG~HHHHHHHHHHHHHHHHHHHTT~~~B~HHHHHHHHHHHHHHHHHHHS~~~~~HHHHS~SS~TTTSGGGGB~~~~~~~SSEEEB~~~HHHH~~~~~~EEEEBTTT~~EEEE~GGGG~~S~~S~~SS~~~TT~SS~GGGB~~~~SS~~~HHHHHHHHHHHHHHHHTSSSS~~HHHHHHHHHHHHHHHHHHSS~~~~HHHHHHHHHHHHHT~TT~TTGGGTT~~EEEE~TT~~SHHHHHHHHHHHHHHHHGGGS~~~EEEE~~~~SSSSS~~EE~SSBSS~B~EE~~TTS~~EE~GGGHHHHHHHHHTT~~~~~SSS~B~~EEEE~TT~~~EEE~~~GGG~~EEE~~~SS~GGGGGG~~EEES~~EE~S~EEEETTEEES~~~EE~~~BHHHHHTHHHH~TTTT~~HHHHHHHT~~~TT~GGG~HHHHHHHHHHHHHHHHHHHTT~~~B~HHHHHHHHHHHHHHHHHHHS~~~~~HHHHS~SS~TTTSGGGGB~~~~~~~SSEEEB~~~GGGS~~~~

Q Y V R I K N W G S G E I L H D T L H H K A T S D F T C K S K S C L G S I M N P K S L T R G P R D K P T P L E E L L P H A I E F I N Q Y Y G S F K E A K I E E H L A R L E A V T K E I E T T G T Y Q L T L D E L I F A T K M A W R N A P R C I G R I Q W S N L Q V F D A R N C S T A Q E M F Q H I C R H I L Y A T N N G N I R S A I T V F P Q R S D G K H D F R L W N S Q L I R Y A G Y Q M P D G T I R G D A A T L E F T Q L C I D L G W K P R Y G R F D V L P L V L Q A D G Q D P E V F E I P P D L V L E V T M E H P K Y E W F Q E L G L K W Y A L P A V A N M L L E V G G L E F P A C P F N G W Y M G T E I G V R D F C D T Q R Y N I L E E V G R R M G L E T H T L A S L W K D R A V T E I N V A V L H S F Q K Q N V T I M D H H T A S E S F M K H M Q N E Y R A R G G C P A D W I W L V P P V S G S I T P V F H Q E M L N Y V L S P F Y Y Y Q I E P W K T H I W Q Q Y V R I K N W G S G E I L H D T L H H K A T S D F T C K S K S C L G S I M N P K S L T R G P R D K P T P L E E L L P H A I E F I N Q Y Y G S F K E A K I E E H L A R L E A V T K E I E T T G T Y Q L T L D E L I F A T K M A W R N A P R C I G R I Q W S N L Q V F D A R N C S T A Q E M F Q H I C R H I L Y A T N N G N I R S A I T V F P Q R S D G K H D F R L W N S Q L I R Y A G Y Q M P D G T I R G D A A T L E F T Q L C I D L G W K P R Y G R F D V L P L V L Q A D G Q D P E V F E I P P D L V L E V T M E H P K Y E W F Q E L G L K W Y A L P A V A N M L L E V G G L E F P A C P F N G W Y M G T E I G V R D F C D T Q R Y N I L E E V G R R M G L E T H T L A S L W K D R A V T E I N V A V L H S F Q K Q N V T I M D H H T A S E S F M K H M Q N E Y R A R G G C P A D W I W L V P P V S G S I T P V F H Q E M L N Y V L S P F Y Y Y Q I E P W K T H I W Q

AH

UNSTRUCTURED

5A5N

SMQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQPMDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRACALRDTAYAIIKEELDEDFEQLCEEIQESR

~HHHHHHHHHHHHHHHHHHHHHHESGGGGGGSS~~~TTT~TTHHHH~SS~~~HHHHHHHHHTT~~SSHHHHHHHHHHHHHHHHHH~~SSSHHHHHHHHHHHHHHHHHHHHHHHH~~HHHHHHHHHHHHH~

S M Q E E D T F R E L R I F L R N V T H R L A I D K R F R V F T K P V D P D E V P D Y V T V I K Q P M D L S S V I S K I D L H K Y L T V K D Y L R D I D L I C S N A L E Y N P D R D P G D R L I R H R A C A L R D T A Y A I I K E E L D E D F E Q L C E E I Q E S R

AH

UNSTRUCTURED

3N4D

TYTCWSQRIRISREAKQRIAEAITDAHHELAHAPKYLVQVIFNEVEPDSYFIAAQSASENHIWVQATIRSGRTEKQKEELLLRLTQEIALILGIPNEEVWVYITEIPGSNMTEYGRLLMEPGEEEKWFNSLPEGLRERLTELEGTYTCWSQRIRISREAKQRIAEAITDAHHELAHAPKYLVQVIFNEVEPDSYFIAAQSASENHIWVQATIRSGRTEKQKEELLLRLTQEIALILGIPNEEVWVYITEIPGSNMTEYGRLLMEPGEEEKWFNSLPEGLRERLTELEGTYTCWSQRIRISREAKQRIAEAITDAHHELAHAPKYLVQVIFNEVEPDSYFIAAQSASENHIWVQATIRSGRTEKQKEELLLRLTQEIALILGIPNEEVWVYITEIPGSNMTEYGRLLMEPGEEEKWFNSLPEGLRERLTELEGSTYTCWSQRIRISREAKQRIAEAITDAHHELAHAPKYLVQVIFNEVEPDSYFIAAQSASENHIWVQATIRSGRTEKQKEELLLRLTQEIALILGIPNEEVWVYITEIPGSNMTEYGRLLMEPGEEEKWFNSLPEGLRERLTELEGTYTCWSQRIRISREAKQRIAEAITDAHHELAHAPKYLVQVIFNEVEPDSYFIAAQSASENHIWVQATIRSGRTEKQKEELLLRLTQEIALILGIPNEEVWVYITEIPGSNMTEYGRLLMEPGEEEKWFNSLPEGLRERLTELEGTYTCWSQRIRISREAKQRIAEAITDAHHELAHAPKYLVQVIFNEVEPDSYFIAAQSASENHIWVQATIRSGRTEKQKEELLLRLTQEIALILGIPNEEVWVYITEIPGSNMTEYGRLLMEPGEEEKWFNSLPEGLRERLTELEGTYTCWSQRIRISREAKQRIAEAITDAHHELAHAPKYLVQVIFNEVEPDSYFIAAQSASENHIWVQATIRSGRTEKQKEELLLRLTQEIALILGIPNEEVWVYITEIPGSNMTEYGRLLMEPGEEEKWFNSLPEGLRERLTELEGTYTCWSQRIRISREAKQRIAEAITDAHHELAHAPKYLVQVIFNEVEPDSYFIAAQSASENHIWVQATIRSGRTEKQKEELLLRLTQEIALILGIPNEEVWVYITEIPGSNMTEYGRLLMEPGEEEKWFNSLPEGLRERLTYTCWSQRIRISREAKQRIAEAITDAHHELAHAPKYLVQVIFNEVEPDSYFIAAQSASENHIWVQATIRSGRTEKQKEELLLRLTQEIALILGIPNEEVWVYITEIPGSNMTEYGRLLMEPGEEEKWFNSLPEGLRERLTELEG

~EEEEEETTTS~HHHHHHHHHHHHHHHHTTTT~~GGG~EEEEEEE~TTSEEETTEE~~TT~EEEEEEEETT~~HHHHHHHHHHHHHHHHHHHT~~GGGEEEEEEEE~GGGEEETTEE~~~SS~HHHHHTTS~HHHHHHHHHH~~~EEEEEETTTS~HHHHHHHHHHHHHHHHHTT~~~GGG~EEEEEEE~GGGEEETTEE~~TT~EEEEEEEETT~~HHHHHHHHHHHHHHHHHHHT~~GGGEEEEEEEE~GGGEEETTEE~~STT~HHHHHHTS~HHHHHHHHHH~~~EEEEEETTSS~HHHHHHHHHHHHHHHHHHHT~~GGG~EEEEEEE~TT~EEETTEE~~TT~EEEEEEEES~~~HHHHHHHHHHHHHHHHHHHT~~GGGEEEEEEEE~GGG~EETTEE~~SSS~HHHHHTTS~HHHHHHHHHHHH~~EEEEEETTSS~HHHHHHHHHHHHHHHHHHH~~~GGG~EEEEEEE~TTSEEETTEE~~TT~EEEEEEEES~~~HHHHHHHHHHHHHHHHHHHT~~GGGEEEEEEEE~GGGEEETTEE~~STT~HHHHHTTS~HHHHHHHHHHT~~EEEEEETTSS~HHHHHHHHHHHHHHHHHHH~~~GGG~EEEEEEE~TTSEEETTEE~~TT~EEEEEEEES~~~HHHHHHHHHHHHHHHHHHTTS~GGGEEEEEEEE~GGGEEETTEE~~STT~HHHHHHTS~HHHHHHHHHHH~~EEEEEETTSS~HHHHHHHHHHHHHHHTTTT~~~GGG~EEEEEEE~SS~EEETTEE~~TT~EEEEEEEETT~~HHHHHHHHHHHHHHHHHHHT~~GGGEEEEEEEE~GGGEEETTEEE~STTTHHHHHHTS~HHHHHHHHHHT~~EEEEEETTSS~HHHHHHHHHHHHHHHHTTTT~~GGG~EEEEEEE~TTSEEETTEE~~TT~EEEEEEEETT~~HHHHHHHHHHHHHHHHHHTT~~GGGEEEEEEEE~GGGEEETTEE~~STT~HHHHHHHS~HHHHHHHHHTT~~EEEEEETTSS~HHHHHHHHHHHHHHHHTTS~~~GGG~EEEEEEE~GGGEEETTEE~~TT~EEEEEEEES~~~HHHHHHHHHHHHHHHHHHTT~~GGGEEEEEEEE~GGGEEETTEE~~STT~HHHHHHTS~HHHHH~~~EEEEEETTTS~HHHHHHHHHHHHHHHHTTTT~~GGG~EEEEEEE~SS~EEETTEE~~TT~EEEEEEEES~~~HHHHHHHHHHHHHHHHHHHT~~GGGEEEEEEEE~GGGEEETTEEE~STT~HHHHHHTS~TTHHHHHHHHH~

T Y T C W S Q R I R I S R E A K Q R I A E A I T D A H H E L A H A P K Y L V Q V I F N E V E P D S Y F I A A Q S A S E N H I W V Q A T I R S G R T E K Q K E E L L L R L T Q E I A L I L G I P N E E V W V Y I T E I P G S N M T E Y G R L L M E P G E E E K W F N S L P E G L R E R L T E L E G T Y T C W S Q R I R I S R E A K Q R I A E A I T D A H H E L A H A P K Y L V Q V I F N E V E P D S Y F I A A Q S A S E N H I W V Q A T I R S G R T E K Q K E E L L L R L T Q E I A L I L G I P N E E V W V Y I T E I P G S N M T E Y G R L L M E P G E E E K W F N S L P E G L R E R L T E L E G T Y T C W S Q R I R I S R E A K Q R I A E A I T D A H H E L A H A P K Y L V Q V I F N E V E P D S Y F I A A Q S A S E N H I W V Q A T I R S G R T E K Q K E E L L L R L T Q E I A L I L G I P N E E V W V Y I T E I P G S N M T E Y G R L L M E P G E E E K W F N S L P E G L R E R L T E L E G S T Y T C W S Q R I R I S R E A K Q R I A E A I T D A H H E L A H A P K Y L V Q V I F N E V E P D S Y F I A A Q S A S E N H I W V Q A T I R S G R T E K Q K E E L L L R L T Q E I A L I L G I P N E E V W V Y I T E I P G S N M T E Y G R L L M E P G E E E K W F N S L P E G L R E R L T E L E G T Y T C W S Q R I R I S R E A K Q R I A E A I T D A H H E L A H A P K Y L V Q V I F N E V E P D S Y F I A A Q S A S E N H I W V Q A T I R S G R T E K Q K E E L L L R L T Q E I A L I L G I P N E E V W V Y I T E I P G S N M T E Y G R L L M E P G E E E K W F N S L P E G L R E R L T E L E G T Y T C W S Q R I R I S R E A K Q R I A E A I T D A H H E L A H A P K Y L V Q V I F N E V E P D S Y F I A A Q S A S E N H I W V Q A T I R S G R T E K Q K E E L L L R L T Q E I A L I L G I P N E E V W V Y I T E I P G S N M T E Y G R L L M E P G E E E K W F N S L P E G L R E R L T E L E G T Y T C W S Q R I R I S R E A K Q R I A E A I T D A H H E L A H A P K Y L V Q V I F N E V E P D S Y F I A A Q S A S E N H I W V Q A T I R S G R T E K Q K E E L L L R L T Q E I A L I L G I P N E E V W V Y I T E I P G S N M T E Y G R L L M E P G E E E K W F N S L P E G L R E R L T E L E G T Y T C W S Q R I R I S R E A K Q R I A E A I T D A H H E L A H A P K Y L V Q V I F N E V E P D S Y F I A A Q S A S E N H I W V Q A T I R S G R T E K Q K E E L L L R L T Q E I A L I L G I P N E E V W V Y I T E I P G S N M T E Y G R L L M E P G E E E K W F N S L P E G L R E R L T Y T C W S Q R I R I S R E A K Q R I A E A I T D A H H E L A H A P K Y L V Q V I F N E V E P D S Y F I A A Q S A S E N H I W V Q A T I R S G R T E K Q K E E L L L R L T Q E I A L I L G I P N E E V W V Y I T E I P G S N M T E Y G R L L M E P G E E E K W F N S L P E G L R E R L T E L E G

AH

BS

4HK5

PVVVDIHTHMYPPSYIAMLEKRQTIPLVRTFPRLILLSSELAALDAALLPGRPLSTHFASLAQKMHFMDTNGIRVSVISLANPWFDFLAPDEAPGIADAVNAEFSDMCAQHVGRLFFFAALPLSAPVDAVKASIERVKNLKYCRGIILGTSGLGKGLDDPHLLPVFEAVADAKLLVFLHPHYGLPNEVYGPRSEEYGHVLPLALGFPMETTIAVARMYMAGVFDHVRNLQMLLAHSGGTLPFLAGRIESCIVHDGHLVKTGKVPKDRRTIWTVLKEQIYLDAVIYSEVGLQAAIASSGADRLMFGTDHPFFPPIEEDVQGPWDSSRLNAQAVIKAVGEGSSDAAAVMGLNAVRVLSLKPVVVDIHTHMYPPSYIAMLEKRQTIPLVPRLILLSSELAALDALPGRPLSTHFASLAQKMHFMDTNGIRVSVISLANPWFDFLAPDEAPGIADAVNAEFSDMCAQHVGRLFFFAALPLSAPVDAVKASIERVKNLKYCRGIILGTSGLGKGLDDPHLLPVFEAVADAKLLVFLHPHYGLPNEVYGPRSEEYGHVLPLALGFPMETTIAVARMYMAGVFDHVRNLQMLLAHSGGTLPFLAGRIESCIVHDGHLVKTGKVPKDRRTIWTVLKEQIYLDAVIYSEVGLQAAIASSGADRLMFGTDHPFFPPIEEDVQGPWDSSRLNAQAVIKAVGEGSSDAAAVMGLNAVRVLSLKAELEHHHHHTPVVVDIHTHMYPPSYIAMLEKRQTIPLVRTFPQADEPRLILLSSELAALDAALADPAAKLPGRPLSTHFASLAQKMHFMDTNGIRVSVISLANPWFDFLAPDEAPGIADAVNAEFSDMCAQHVGRLFFFAALPLSAPVDAVKASIERVKNLKYCRGIILGTSGLGKGLDDPHLLPVFEAVADAKLLVFLHPHYGLPNEVYGPRSEEYGHVLPLALGFPMETTIAVARMYMAGVFDHVRNLQMLLAHSGGTLPFLAGRIESCIVHDGHLVKTGKVPKDRRTIWTVLKEQIYLDAVIYSEVGLQAAIASSGADRLMFGTDHPFFPPIEEDVQGPWDSSRLNAQAVIKAVGEGSSDAAAVMGLNAVRVLSLKTPVVVDIHTHMYPPSYIAMLEKRQTIPLVRTFPQADEPRLILLSSELAALDAALADPAAKLPGRPLSTHFASLAQKMHFMDTNGIRVSVISLANPWFDFLAPDEAPGIADAVNAEFSDMCAQHVGRLFFFAALPLSAPVDAVKASIERVKNLKYCRGIILGTSGLGKGLDDPHLLPVFEAVADAKLLVFLHPHYGLPNEVYGPRSEEYGHVLPLALGFPMETTIAVARMYMAGVFDHVRNLQMLLAHSGGTLPFLAGRIESCIVHDGHLVKTGKVPKDRRTIWTVLKEQIYLDAVIYSEVGLQAAIASSGADRLMFGTDHPFFPPIEEDVQGPWDSSRLNAQAVIKAVGEGSSDAAAVMGLNAVRVLSLKAELEHHHHHH

~~~EEEEEEE~~HHHHHHHHH~SSSSEEE~~~EEE~~GGGHHHHHHH~~~SEE~~HHHH~HHHHHHHHHHTT~SEEEEEE~TTTTTTS~TTTHHHHHHHHHHHHHHHHHTTTTTEEEEEE~~TTS~HHHHHHHHHHHTTSTTEEEEEEETTBTTTBTT~GGGHHHHHHHHHTT~EEEEE~~S~S~GGGG~TTGGGGTTHHHHHTHHHHHHHHHHHHHHHTTHHHHSTT~~EEEGGGGTTHHHHHHHHHHHHHT~HHHHHTT~S~TT~~~HHHHHHHTEEEE~TTSSHHHHHHHHHHH~GGGEE~~~~BTSS~~SSS~TTS~~HHHHHHHHHHHHHH~TTSHHHHHHHTHHHHHHTT~~~~~EEEEEEE~~HHHHHHHHH~~SSSB~~EEB~SGGGHHHHH~~~SEE~~HHHH~HHHHHHHHHHTT~SEEEEEE~TTTTTTS~TTTHHHHHHHHHHHHHHHHHTTTTTEEEEEE~~TTS~HHHHHHHHHHHTTSTTEEEEEEETTBTTTBTT~GGGHHHHHHHHHTT~EEEEE~~S~S~GGGG~TTGGGGTTHHHHHTHHHHHHHHHHHHHHHTTHHHHSTT~~EEEGGGGTTHHHHHHHHHHHHHT~HHHHHTTSS~TT~~~HHHHHHHTEEEE~TTSSHHHHHHHHHHH~GGGEE~~~~BTSS~~SSS~TTS~~HHHHHHHHHHHHHH~TT~HHHHHHHTHHHHHHTT~~TT~SS~~~~~~~~EEEEEEE~~HHHHHHHHH~SSSSEEE~~SS~SS~EEE~~GGGHHHHHHHHH~TTS~~~SEE~~GGGT~HHHHHHHHHHTT~SEEEEEE~TTTTTTS~TTTHHHHHHHHHHHHHHHHHTTTTTEEEEEE~~TTS~HHHHHHHHHHHHTSTTEEEEEE~TTBTTTBTT~GGGHHHHHHHHHTT~EEEE~~~S~S~GGGG~TTGGGSTTHHHHHTHHHHHHHHHHHHHHHTTHHHHSTT~~EEEGGGGTTHHHHHHHHHHHHHT~HHHHHTT~S~TT~~~HHHHHHHTEEEE~TTSSHHHHHHHHHHH~GGGEE~~~~BTSS~~SSTT~~SS~HHHHHHHHHHHHHH~TT~HHHHHHHTHHHHHHTT~~~~~~EEEEEEE~~HHHHHHHHT~SSSSEEEEETTEEEEEEE~~GGGHHHHHHHHH~TTS~~~SEE~~GGGT~HHHHHHHHHHTT~SEEEEEE~TTTTTTS~TTTHHHHHHHHHHHHHHHHHTTTTTEEEEEE~~TTS~HHHHHHHHHHHHTSTTEEEEEE~TTBTTTBTT~GGGHHHHHHHHHTT~EEEE~~~S~S~GGGG~TTGGGSTTHHHHHTHHHHHHHHHHHHHHHTTHHHHSTT~~EEEGGGGTTHHHHHHHHHHHHHT~HHHHHTT~S~TT~~~HHHHHHHTEEEE~TTSSHHHHHHHHHHH~GGGEE~~~~BTSS~~SSS~TTS~~HHHHHHHHHHHHHH~TT~HHHHHHHTHHHHHHTT~HHHHHHHHHH~

P V V V D I H T H M Y P P S Y I A M L E K R Q T I P L V R T F P R L I L L S S E L A A L D A A L L P G R P L S T H F A S L A Q K M H F M D T N G I R V S V I S L A N P W F D F L A P D E A P G I A D A V N A E F S D M C A Q H V G R L F F F A A L P L S A P V D A V K A S I E R V K N L K Y C R G I I L G T S G L G K G L D D P H L L P V F E A V A D A K L L V F L H P H Y G L P N E V Y G P R S E E Y G H V L P L A L G F P M E T T I A V A R M Y M A G V F D H V R N L Q M L L A H S G G T L P F L A G R I E S C I V H D G H L V K T G K V P K D R R T I W T V L K E Q I Y L D A V I Y S E V G L Q A A I A S S G A D R L M F G T D H P F F P P I E E D V Q G P W D S S R L N A Q A V I K A V G E G S S D A A A V M G L N A V R V L S L K P V V V D I H T H M Y P P S Y I A M L E K R Q T I P L V P R L I L L S S E L A A L D A L P G R P L S T H F A S L A Q K M H F M D T N G I R V S V I S L A N P W F D F L A P D E A P G I A D A V N A E F S D M C A Q H V G R L F F F A A L P L S A P V D A V K A S I E R V K N L K Y C R G I I L G T S G L G K G L D D P H L L P V F E A V A D A K L L V F L H P H Y G L P N E V Y G P R S E E Y G H V L P L A L G F P M E T T I A V A R M Y M A G V F D H V R N L Q M L L A H S G G T L P F L A G R I E S C I V H D G H L V K T G K V P K D R R T I W T V L K E Q I Y L D A V I Y S E V G L Q A A I A S S G A D R L M F G T D H P F F P P I E E D V Q G P W D S S R L N A Q A V I K A V G E G S S D A A A V M G L N A V R V L S L K A E L E H H H H H T P V V V D I H T H M Y P P S Y I A M L E K R Q T I P L V R T F P Q A D E P R L I L L S S E L A A L D A A L A D P A A K L P G R P L S T H F A S L A Q K M H F M D T N G I R V S V I S L A N P W F D F L A P D E A P G I A D A V N A E F S D M C A Q H V G R L F F F A A L P L S A P V D A V K A S I E R V K N L K Y C R G I I L G T S G L G K G L D D P H L L P V F E A V A D A K L L V F L H P H Y G L P N E V Y G P R S E E Y G H V L P L A L G F P M E T T I A V A R M Y M A G V F D H V R N L Q M L L A H S G G T L P F L A G R I E S C I V H D G H L V K T G K V P K D R R T I W T V L K E Q I Y L D A V I Y S E V G L Q A A I A S S G A D R L M F G T D H P F F P P I E E D V Q G P W D S S R L N A Q A V I K A V G E G S S D A A A V M G L N A V R V L S L K T P V V V D I H T H M Y P P S Y I A M L E K R Q T I P L V R T F P Q A D E P R L I L L S S E L A A L D A A L A D P A A K L P G R P L S T H F A S L A Q K M H F M D T N G I R V S V I S L A N P W F D F L A P D E A P G I A D A V N A E F S D M C A Q H V G R L F F F A A L P L S A P V D A V K A S I E R V K N L K Y C R G I I L G T S G L G K G L D D P H L L P V F E A V A D A K L L V F L H P H Y G L P N E V Y G P R S E E Y G H V L P L A L G F P M E T T I A V A R M Y M A G V F D H V R N L Q M L L A H S G G T L P F L A G R I E S C I V H D G H L V K T G K V P K D R R T I W T V L K E Q I Y L D A V I Y S E V G L Q A A I A S S G A D R L M F G T D H P F F P P I E E D V Q G P W D S S R L N A Q A V I K A V G E G S S D A A A V M G L N A V R V L S L K A E L E H H H H H H

AH

T

5EKN

SLIRKKGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIMGMEFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQSLPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQQPFDDSLEHEKLTVDEWKQHIYKEIVNFSP

~~SS~TTEEEEESSSSEEEEETTEEEEEEEEE~SSEEEEEEEETTT~~EEEEEEESSTTSSHHHHHHHHHHHHHHHH~~~TTB~~~SEEE~S~SSSSS~~~~EEEEE~~SEETTTSTTS~~~HHHHHHHHHHHHHHHHHHHHTT~~~S~~~GGGEEE~TT~~EEE~~~~~~TTS~HHHHS~~S~~~THHHHHHHHHHHHHHHHSS~S~~~SSHHHHHHHHHHHH~~~~HHHHTT~S~HHHHHHHHHS~~~~~~~HHHH~TTS~HHHHHHHHHHS~S~TTTS~~HHHHHTSGGGTTT~~GGG~~~~SS~~~~GGGS~~~~HHHHHHHHHHHHHT~~~

S L I R K K G F Y K Q D V N K T A W E L P K T Y V S P T H V G S G A Y G S V C S A I D K R S G E K V A I K K L S R P F Q S E I F A K R A Y R E L L L L K H M Q H E N V I G L L D V F T P A S S L R N F Y D F Y L V M P F M Q T D L Q K I M G M E F S E E K I Q Y L V Y Q M L K G L K Y I H S A G V V H R D L K P G N L A V N E D C E L K I L D F V T R W Y R A P E V I L S W M H Y N Q T V D I W S V G C I M A E M L T G K T L F K G K D Y L D Q L T Q I L K V T G V P G T E F V Q K L N D K A A K S Y I Q S L P Q T P R K D F T Q L F P R A S P Q A A D L L E K M L E L D V D K R L T A A Q A L T H P F F E P F R D P E E E T E A Q Q P F D D S L E H E K L T V D E W K Q H I Y K E I V N F S P

AH

UNSTRUCTURED

4ZQK

AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNANPPTFSPALLVVTEGDNATFTCSFSNTSESFVLNWYRMSPSNQTDKLAAFPESRFRVTQLPNGRDFHMSVVRARRNDSGTYLCGAISLAPKAQIKESLRAELRVTE

~~~~B~S~SEEEEETTS~EEEEEE~~~~SS~~GGG~EEEEEETTEEEEEEETTEE~GGGS~GGGTTTEEEHHHGGGGTEEEEEESS~~GGG~EEEEEEEESSSEEEEEEEEEEE~~~~EEE~SEEEEETTS~EEEEEE~~~~~SEEEEEEEEE~SSS~EEEEEEE~~~~EEEEE~TTSSEEEEEESS~~STT~EEEEEEEEEEESS~EEEE~~~EEEEEE~

A F T V T V P K D L Y V V E Y G S N M T I E C K F P V E K Q L D L A A L I V Y W E M E D K N I I Q F V H G E E D L K V Q H S S Y R Q R A R L L K D Q L S L G N A A L Q I T D V K L Q D A G V Y R C M I S Y G G A D Y K R I T V K V N A N P P T F S P A L L V V T E G D N A T F T C S F S N T S E S F V L N W Y R M S P S N Q T D K L A A F P E S R F R V T Q L P N G R D F H M S V V R A R R N D S G T Y L C G A I S L A P K A Q I K E S L R A E L R V T E

BS

UNSTRUCTURED

2KCN

AKYTGKCTKSKNECKYKNDAGKDTFIKCPKFDNKKCTKDNNKCTVDTYNNAVDCD

~EEEE~~~HS~~EEEEEETTTEEEEEE~S~TTT~~~~STT~~EEEETTTTEEEE~

A K Y T G K C T K S K N E C K Y K N D A G K D T F I K C P K F D N K K C T K D N N K C T V D T Y N N A V D C D

BS

UNSTRUCTURED

4QLO

NYTVDTLNLGEFITESGEVIDNLRLRYEHVGYHGQPLVVVCHALTGNHLTYGTDDYPGWWREIIDGGYIPIHDYQFLTFDVIGSPFGSSSPLNDPHFPKKLTLRDIVRANERGIQALGYDKINILIGGSLGGMQAMELLYNQQFEVDKAIILAATSRTSSYSRAFNEIARQAIHLGGKEGLSIARQLGFLTYRSSKSYDERFTPDEVVAYQQHQGNKFKEHFDLNCYLTLLDVLDSHNIDRGRTDVTHVFKNLETKVLTMGFIDDLLYPDDQVRALGERFKYHRHFFVPDNVGHDGFLLNFSTWAPNLYHFLNLKHFKRKDPAFLYK

~EEEEEEE~~~EE~TTS~EESS~EEEEEEES~TTS~EEEEE~~TT~~S~SSB~SSSB~TTHHHHHTTSS~TTT~EEEEE~~TT~SSSSS~TTT~TT~~S~~~HHHHHHHHHHHHHHTT~~EEEEEEEESHHHHHHHHHHHHT~SEEEEEEEES~~SB~~HHHHHHHHHHHHHHHHHTHHHHHHHHHGGGGGB~~~THHHH~~~TTTTHHHHHHHHHHHHHHS~HHHHHHHHHHHHT~BTTTT~S~HHHHHHT~~~EEEEEEETTBSSS~HHHHHHHHTTSSEEEEEEES~~S~GGGTTTTGGGTHHHHHHHHT~~S~~~~SGGG~~~

N Y T V D T L N L G E F I T E S G E V I D N L R L R Y E H V G Y H G Q P L V V V C H A L T G N H L T Y G T D D Y P G W W R E I I D G G Y I P I H D Y Q F L T F D V I G S P F G S S S P L N D P H F P K K L T L R D I V R A N E R G I Q A L G Y D K I N I L I G G S L G G M Q A M E L L Y N Q Q F E V D K A I I L A A T S R T S S Y S R A F N E I A R Q A I H L G G K E G L S I A R Q L G F L T Y R S S K S Y D E R F T P D E V V A Y Q Q H Q G N K F K E H F D L N C Y L T L L D V L D S H N I D R G R T D V T H V F K N L E T K V L T M G F I D D L L Y P D D Q V R A L G E R F K Y H R H F F V P D N V G H D G F L L N F S T W A P N L Y H F L N L K H F K R K D P A F L Y K

AH

UNSTRUCTURED

5D58

GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWMITSTEHLRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWKKNQPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRI

~~~BTTB~THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEESS~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT~HHHHHHHHHHHHHHHHHHHHSS~~THHHHHHHHHHHHHHHHHHHHHHHHHHHTS~SS~TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~HHHHHHHHHHHHHHHHHHHHHHHHHHS~GGGGS~SS~~~GGGHHHHHHHHHHHHHHHHHHHHHHHHTT~~SHHHHHHHHHHHHHHHHHHHHHH~~~TTTHHHHHHHHHHHHHHHHHHHHHHGGGTHHHHHHHHHB~~TTS~GGGGGGHHHHHHHHHHHHHHHHHHH~TTT~~~HHHHHHHHHHHHHHHHHHHHHHHHHH~SSS~B~THHHHHHHHHHHHHHHHH~~HHHHHHHHHHHHHHHHHHGGG~STTTHHHHHHHHHHHHHHHHHHHHHHTTT~

G K T F F G Q P L G L S T L F M T E M W E R F S Y Y G M R A I L L Y Y M W F L I S T G D L H I T R A T A A S I M A I Y A S M V Y L S G T I G G F V A D R I I G A R P A V F W G G V L I M L G H I V L A L P F G A S A L F G S I I L I I I G T G F L K P N V S T L V G T L Y D E H D R R R D A G F S I F V F G I N L G A F I A P L I V G A A Q E A A G Y H V A F S L A A I G M F I G L L V Y Y F G G K K T L D P H Y L R P T D P L A P E E V K P L L V K V S L A V A G F I A I I V V M N L V G W N S L P A Y I N L L T I V A I A I P V F Y F A W M I T S T E H L R V V S Y I P L F I A A V L F W A I E E Q G S V V L A T F A A E R V D S S W F P V S W F Q S L N P L F I M L Y T P F F A W L W T A W K K N Q P S S P T K F A V G L M F A G L S F L L M A I P G A L Y G T S G K V S P L W L V G S W A L V I L G E M L I S M M S M W F L S S S V G S A L N A Q L V T L Y N A K S E V A Y F S Y F G L G S V V L G I V L V F L S K R I

AH

UNSTRUCTURED

2J0U

PTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSVSVLQCLDIQVRETQALILAPTRELAVQVQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAVNFVKNDDIRVLRDIEQYYSTQIDEMPMNVAPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSVSVLQCLDIQVRETQALILAPTRELAVQVQKGLLALGDYMNVQSHACIGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEVLEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMRETVSQKERESIMKEFRSGASRVLISTVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAVNFVKNDDIRVLRDIEQYYSTQIDEMPMNVRWEHDKFRE

~~SGGG~~~HHHHHHHHHTT~~S~~HHHHHHHHHHHHT~~EEEE~~SSTTTTHHHHHHHHHH~~SSS~S~~EEEE~S~HHHHHHHHHHHHHHHTTTT~~~~EE~~~S~HHHHHHHHHT~~SEEEE~HHHHHHHHHTS~S~~TT~~EEEETTHHHHHTTT~HHHHHHHHHTS~TT~EEEEEES~~~HHHHHHHHHH~SS~EEE~SS~~~~~STT~EEEEEE~~STTSHHHHHHHH~~~~~EEEE~SSHHHHHHHHHHHHHSS~~EEEE~SSS~HHHHHHHHHHHHHTS~SEEEE~STT~~~~~~~SEEEESS~~SSHHHHHHHS~~~SSSS~~~EEEEEE~GGGHHHHHHHHHHHT~~~EE~~S~~~~~SGGG~~~HHHHHHHHHTT~~S~~HHHHHHHHHHHTT~~EEE~~~SSTTTTHHHHHHHHHH~~TTS~S~~EEEE~S~HHHHHHHHHHHHHHHTTTT~~EEE~~~TTHHHHHT~~SEEEE~HHHHHHHHHTS~S~~TT~~EEEETTHHHHTTTT~HHHHHHHHHTS~TT~EEEEE~S~~~HHHHHHHHHH~SS~EEE~SS~~~~~SSSEEEEEEE~~SSSSHHHHHHHTHHHHHHH~EEEE~SSHHHHHHHHHHHT~~~~~~SHHHHHHHHHHTS~SEE~~~~~~~SEEEESS~~SSTTTHHHHS~~~SSS~~~EEEEEEE~GGGHHHHHHHHHHHT~~~EE~~S~~~~~~~S~~~

P T F D T M G L R E D L L R G I Y A Y G F E K P S A I Q Q R A I K Q I I K G R D V I A Q S Q S G T G K T A T F S V S V L Q C L D I Q V R E T Q A L I L A P T R E L A V Q V Q K G L L A L G D Y M N V Q C H A C I G G T N V G E D I R K L D Y G Q H V V A G T P G R V F D M I R R R S L R T R A I K M L V L D E A D E M L N K G F K E Q I Y D V Y R Y L P P A T Q V V L I S A T L P H E I L E M T N K F M T D P I R I L V K R D E L T L E G I K Q F F V A V E R E E W K F D T L C D L Y D I T Q A V I F C N T K R K V D W L T E K M R E A N F T V S S M H G D M P Q K E R E S I M K E F R S G A S R V L I S T D V W A R D V P Q V S L I I N Y D L P N N R E L Y I H R I G R S G R Y G R K G V A V N F V K N D D I R V L R D I E Q Y Y S T Q I D E M P M N V A P T F D T M G L R E D L L R G I Y A Y G F E K P S A I Q Q R A I K Q I I K G R D V I A Q S Q S G T G K T A T F S V S V L Q C L D I Q V R E T Q A L I L A P T R E L A V Q V Q K G L L A L G D Y M N V Q S H A C I G E D I R K L D Y G Q H V V A G T P G R V F D M I R R R S L R T R A I K M L V L D E A D E M L N K G F K E Q I Y D V Y R Y L P P A T Q V V L I S A T L P H E V L E M T N K F M T D P I R I L V K R D E L T L E G I K Q F F V A V E R E E W K F D T L C D L Y D T L T I T Q A V I F C N T K R K V D W L T E K M R E T V S Q K E R E S I M K E F R S G A S R V L I S T V P Q V S L I I N Y D L P N N R E L Y I H R I G R S G R Y G R K G V A V N F V K N D D I R V L R D I E Q Y Y S T Q I D E M P M N V R W E H D K F R E

AH

UNSTRUCTURED

5V0I

KPIVFSGAQPSLTIGNYMGALRQWVNMQDDYHCIYCIVDQHAITVRQDAQKLRKATLDTLALYLACGIDPEKSTIFVQSHVPEHAQLGWALNCYTYFGELSRMTAENINAGLFDYPVLMAADILLYQTNLVPVGEDQKQHLELSRDIAQRFNALYGDIFKVPEPFIPKSGARVMSLLEPTKKMSKSDDNRNNVIGLLEDPKSVVKKIKRAVTDSDEPPVVRYDVQNKAGVSNLLDILSAVTGQSIPELEKQFEGKMYGHLKGEVADAVSGMLTELQERYHRFRNDEAFLQQVMKDGAEKASAHASRTLKAVYEAIGFVAKPTKPIVFSGAQPSGELTIGNYMGALRQWVNMQDDYHCIYCIVDQHAITVRQDAQKLRKATLDTLALYLACGIDPEKSTIFVQSHVPEHAQLGWALNCYTYFGELSRMTQFKARYAENINAGLFDYPVLMAADILLYQTNLVPVGEDQKQHLELSRDIAQRFNALYGDIFKVPEPFARVMSLLEPTKKMSKSDDNRNNVIGLLEDPKSVVKKIKRAVTDSDEPPVVRYDVQNKAGVSNLLDILSAVTGQSIPELEKQFEGKMYGHLKGEVADAVSGMLTELQERYHRFRNDEAFLQQVMKDGAEKASAHASRTLKAVYEAIGFVAKP

~~EEEEEE~~~~BHHHHHHTHHHHHTTTTTSEEEEEE~HHHHTTS~~~HHHHHHHHHHHHHHHHHHT~~TTTSEEEEGGG~THHHHHHHHHHTTSBHHHHHTT~~~SSBHHHHHHHHHHHHHHHTTT~~EE~~~GGGHHHHHHHHHHHHHHHHHHSS~S~~~EE~~~~~S~~~EETTEEEEE~~TT~S~GGG~~BTT~~HHHHHHHHHTS~~~~~SS~~~~~BTTTBHHHHHHHHHHHHHH~~~HHHHHHHTTT~~HHHHHHHHHHHHHHHHHHHHHHHHHHHT~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT~~~~~~~~EEEEEE~SSS~~BHHHHHHTHHHHHTTTTTSEEEEEE~HHHHTTS~~~HHHHHHHHHHHHHHHHHHT~~TTTSEEEEGGG~THHHHHHHHHHTTSBHHHHHTSTTT~~HHHHHSBHHHHHHHHHHHHHHHTTT~SEE~~~GGGHHHHHHHHHHHHHHHHHHSS~S~~~EE~~~~EETTEEEEE~~TT~S~GGG~~BTT~~HHHHHHHHHT~~~~~~SS~~~~~~TTT~HHHHHHHHHHHHHH~~~HHHHHHHTTT~~HHHHHHHHHHHHHHHHHHHHHHHHHHHT~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT~~~~~

K P I V F S G A Q P S L T I G N Y M G A L R Q W V N M Q D D Y H C I Y C I V D Q H A I T V R Q D A Q K L R K A T L D T L A L Y L A C G I D P E K S T I F V Q S H V P E H A Q L G W A L N C Y T Y F G E L S R M T A E N I N A G L F D Y P V L M A A D I L L Y Q T N L V P V G E D Q K Q H L E L S R D I A Q R F N A L Y G D I F K V P E P F I P K S G A R V M S L L E P T K K M S K S D D N R N N V I G L L E D P K S V V K K I K R A V T D S D E P P V V R Y D V Q N K A G V S N L L D I L S A V T G Q S I P E L E K Q F E G K M Y G H L K G E V A D A V S G M L T E L Q E R Y H R F R N D E A F L Q Q V M K D G A E K A S A H A S R T L K A V Y E A I G F V A K P T K P I V F S G A Q P S G E L T I G N Y M G A L R Q W V N M Q D D Y H C I Y C I V D Q H A I T V R Q D A Q K L R K A T L D T L A L Y L A C G I D P E K S T I F V Q S H V P E H A Q L G W A L N C Y T Y F G E L S R M T Q F K A R Y A E N I N A G L F D Y P V L M A A D I L L Y Q T N L V P V G E D Q K Q H L E L S R D I A Q R F N A L Y G D I F K V P E P F A R V M S L L E P T K K M S K S D D N R N N V I G L L E D P K S V V K K I K R A V T D S D E P P V V R Y D V Q N K A G V S N L L D I L S A V T G Q S I P E L E K Q F E G K M Y G H L K G E V A D A V S G M L T E L Q E R Y H R F R N D E A F L Q Q V M K D G A E K A S A H A S R T L K A V Y E A I G F V A K P

AH

UNSTRUCTURED

3ZYW

DLNLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQFSSFDIFSDEEVRQGLKAYSSWPTYPQLYVSGELIGGLDIIKELEASEELDTICPKAAENLYFQMKEDLNLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQFSSFDIFSDEEVRQGLKAYSSWPTYPQLYVSGELIGGLDIIKELEASEELDTICPKAAENLYFQ

~HHHHHHHHHTSSSEEEEESB~SSSBSSHHHHHHHHHHHHTT~~~EEEEGGG~HHHHHHHHHHHT~~SS~EEEETTEEEE~HHHHHHHHHTT~HHHHS~~~~~~~S~~~~~~HHHHHHHHHTSSSEEEEESB~SSSB~SHHHHHHHHHHHHTT~~~EEEEGGG~HHHHHHHHHHHT~~SSSEEEETTEEEESHHHHHHHHHTT~HHHHS~~~~~~~S~~

D L N L R L K K L T H A A P C M L F M K G T P Q E P R C G F S K Q M V E I L H K H N I Q F S S F D I F S D E E V R Q G L K A Y S S W P T Y P Q L Y V S G E L I G G L D I I K E L E A S E E L D T I C P K A A E N L Y F Q M K E D L N L R L K K L T H A A P C M L F M K G T P Q E P R C G F S K Q M V E I L H K H N I Q F S S F D I F S D E E V R Q G L K A Y S S W P T Y P Q L Y V S G E L I G G L D I I K E L E A S E E L D T I C P K A A E N L Y F Q

AH

UNSTRUCTURED

3N8E

DVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKME

~B~SS~EEEE~TTSBEEEEE~TT~BSSEEEEEEE~~SSTT~~~EEEEEEESS~SBGGGSEEEEEEEE~~~~~~~TT~S~EEEEEEE~TT~~EEEEEEETTT~~EEEEEES~~~~~~HHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHH~~S~~~~~B~SS~EEEEEGGGEEEEEE~TT~BSSEEEEEEE~~SSTT~~~EEEEEEESS~SBGGGSEEEEEEEE~~~~~~~TT~S~EEEEEEE~SS~EEEEEEEETTT~~EEEEEEESS~~S~HHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHT~S~~~~

D V T P L S L G I E T L G G V F T K L I N R N T T I P T K K S Q V F S T A A D G Q T Q V E I K V C Q G E R E M A G D N K L L G Q F T L I G I P P A P R G V P Q I E V T F D I D A N G I V H V S A K D K G T G R E Q Q I V I Q S S G G L S K D D I E N M V K N A E K Y A E E D R R K K E R V E A V N M A E G I I H D T E T K M E D V T P L S L G I E T L G G V F T K L I N R N T T I P T K K S Q V F S T A A D G Q T Q V E I K V C Q G E R E M A G D N K L L G Q F T L I G I P P A P R G V P Q I E V T F D I D A N G I V H V S A K D K G T G R E Q Q I V I Q S S G G L S K D D I E N M V K N A E K Y A E E D R R K K E R V E A V N M A E G I I H D T E T K M E

BS

AH

2ZDP

AHMFMAENRLQLQKGSAEETIERFYNRQGIETIEGFQQMFVTKTLNTEDTDEVKILTIWESEDSFNNWLNSDVFKEAHKNVRLKSDDDGQQSPILSNKVFKYDIGYHYQKAHMFMAENRLQLQKGSAEETIERFYNRQGIETIEGFQQMFVTKTLNTEDTDEVKILTIWESEDSFNNWLNSDVFKEAHKNVRLKSDDDGQQSPILSNKVFKYDIGYHYQK

~~~EEEEEEEEE~TT~HHHHHHTTSS~~SGGGSTTEEEEEEEEE~S~~SSEEEEEEEEES~HHHHHHHHTSHHHHHHTTT~~~TTSTT~TT~~EEEEEEEEEEEEEEEE~~~~EEEEEEEEEETT~HHHHHHTTSS~~SGGGSTTEEEEEEEEE~S~~SEEEEEEEEEES~HHHHHHHHTSHHHHHHHTT~~~TTSTT~TT~~EEEEEEEEEEEEEEEE~

A H M F M A E N R L Q L Q K G S A E E T I E R F Y N R Q G I E T I E G F Q Q M F V T K T L N T E D T D E V K I L T I W E S E D S F N N W L N S D V F K E A H K N V R L K S D D D G Q Q S P I L S N K V F K Y D I G Y H Y Q K A H M F M A E N R L Q L Q K G S A E E T I E R F Y N R Q G I E T I E G F Q Q M F V T K T L N T E D T D E V K I L T I W E S E D S F N N W L N S D V F K E A H K N V R L K S D D D G Q Q S P I L S N K V F K Y D I G Y H Y Q K

BS

AH

1NHA

DVQVTEDAVRRYLTRKPMTTKDLLKKFQTKKTGLSSEQTVNVLAQILKRLNPERKMINDKMHFSLKE

~~~~~HHHHHHHHHHS~B~HHHHHHHTTSS~~SS~HHHHHHHHHHHHHHH~~EEEEETTEEEEE~~~

D V Q V T E D A V R R Y L T R K P M T T K D L L K K F Q T K K T G L S S E Q T V N V L A Q I L K R L N P E R K M I N D K M H F S L K E

AH

UNSTRUCTURED

4Q2G

TASVVAPFVVLCFVSYESLIGLVSAILILAGYELITLEMKERDARFFYVILLALYPVLYGLVFEEPTQPLSILFITGVVFSLITDKDPSQVFKTVAAFSIALIYVTFFLSFFLPIYRDFGAANALLVLTSTWVFDSFAYFTGLKFGRTRISPRYSPRKSLEGVIGGFLGVVIYTFLYRLVVNDLLSVNVICFRTFLPFAATVAIMDTFGDIFESALKRHYGVKDSGKTLPGHGGMLDRIDGLLFVAPVCYIVFKILEGVVRDDLKTRVITASVVAPFVVLCFVSYESLIGLVSAILILAGYELITLEMKERDARFFYVILLALYPVLYGLVFEEPTQPLSILFITGVVFSLITDKDPSQVFKTVAAFSIALIYVTFFLSFFLPIYRDFGAANALLVLTSTWVFDSFAYFTGLKFGRTRISPRYSPRKSLEGVIGGFLGVVIYTFLYRLVVNDLLSVNVICFRTFLPFAATVAIMDTFGDIFESALKRHYGVKDSGKTLPGHGGMLDRIDGLLFVAPVCYIVFKILEGVVR

~HHHHHHHHHTTTTSHHHHHHHHHHHHHHHHHHHHHTT~~SHHHHHHHHHHHHHHHHHHHTTSS~SHHHHHHHHHHHHHHHHHH~~~HHHHHHHHHHHHHHHHHTHHHHTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTS~~~B~S~TTS~~~BHHHHHHHHHHHHHHHHHHHHHHHHSSS~~~~~SSSHHHHHHHHHHHHHHHHHHHHHHHHHHT~SSS~~~SSSSS~HHHHHHHHHHHHHHHHHHHHHHH~~~~~~THHHHHHHHHHHHHHHHHTTSHHHHHHHHHHHHHHHHHHHHHTT~~~HHHHHHHHHHHHHHHHHHHTTSS~SHHHHHHHHHHHHHHHHHH~~~HHHHHHHHHHHHHHHHHTHHHHTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT~~~B~S~TTS~~~BHHHHHHHHHHHHHHHHHHHHHHHHSSS~~~~~SSSHHHHHHHHHHHHHHHHHHHHHHHHHHT~EES~~~SSSSS~HHHHHHHHHHHHHHHHHHHHHHH~~~~

T A S V V A P F V V L C F V S Y E S L I G L V S A I L I L A G Y E L I T L E M K E R D A R F F Y V I L L A L Y P V L Y G L V F E E P T Q P L S I L F I T G V V F S L I T D K D P S Q V F K T V A A F S I A L I Y V T F F L S F F L P I Y R D F G A A N A L L V L T S T W V F D S F A Y F T G L K F G R T R I S P R Y S P R K S L E G V I G G F L G V V I Y T F L Y R L V V N D L L S V N V I C F R T F L P F A A T V A I M D T F G D I F E S A L K R H Y G V K D S G K T L P G H G G M L D R I D G L L F V A P V C Y I V F K I L E G V V R D D L K T R V I T A S V V A P F V V L C F V S Y E S L I G L V S A I L I L A G Y E L I T L E M K E R D A R F F Y V I L L A L Y P V L Y G L V F E E P T Q P L S I L F I T G V V F S L I T D K D P S Q V F K T V A A F S I A L I Y V T F F L S F F L P I Y R D F G A A N A L L V L T S T W V F D S F A Y F T G L K F G R T R I S P R Y S P R K S L E G V I G G F L G V V I Y T F L Y R L V V N D L L S V N V I C F R T F L P F A A T V A I M D T F G D I F E S A L K R H Y G V K D S G K T L P G H G G M L D R I D G L L F V A P V C Y I V F K I L E G V V R

AH

UNSTRUCTURED

1WQQ

KVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRATNYNAGDRSTDFGIFQINSRYWCNDGKTPGAVNACHLSCSALLQDNIADAVACAKRVVRDPQGIRAWVAWRNRCQNRDVRQYVQGCGV

~B~~HHHHHHHHHHTT~TTBTTB~HHHHHHHHHHHHSSBTT~EEEETTTTEEEETTTTEETTTTSB~S~STT~~~TT~~BGGGGGSSS~HHHHHHHHHHHTSTTGGGGSHHHHHHTTTS~~GGGTTTS~~

K V F E R C E L A R T L K R L G M D G Y R G I S L A N W M C L A K W E S G Y N T R A T N Y N A G D R S T D F G I F Q I N S R Y W C N D G K T P G A V N A C H L S C S A L L Q D N I A D A V A C A K R V V R D P Q G I R A W V A W R N R C Q N R D V R Q Y V Q G C G V

AH

T

3OO7

GPITFGSNYSDEAPKAAFASLMQQATTSTTVPVTVNTTDHNTFQNNISNYLQGTPDSLATWFAGYRLQFFAAQGLLTPIDDVWDKIGGTFNDAAKSLSKGLDGHYYLVPLYNYPWVVFYNKSVFQSKGYEVPASWEAFIALARKMQSDGLVPLAFADKDGWPALGTFDILNLRINGYDYHIKLMKHEVPWTDPGVTKVFDQWRELAAYQQKGANGRTWQDAAKALENKQAGMMFQGSNQVAANYSAKNLPDLDFFVFPAINPQYGTDYMDAPTDGFILPKKGKNAAAAKKVLQYIGTAEAEAAFLKTDHWDVGLANGLIAPTYNDIQKKSVAEIGKCKSVSQFMKRDTVPDMANAMIKLIQQFIDQPTPETIATVQKSAEDQAKTIFR

~~EEEEE~~~SHHHHHHHHHHHHHHHHHH~~~EEEEE~~HHHHHHTHHHHHHS~~~SEEEEESSHHHHHHHHTT~B~~~HHHHHHHGGGS~HHHHHTTB~TTS~B~EEEEEE~~EEEEEEHHHHHHHT~~~~~BHHHHHHHHHHHHHTT~EEE~~~~TTSSTTHHHHHHHHHHHT~HHHHHHHHHTSS~TTSHHHHHHHHHHHHHHTTB~TTGGG~~HHHHHHHHHTTSEEEEEEEHHHHHHHS~TTTGGGEEEE~~~BSSTTTTT~EEE~~~EEEE~BTT~S~HHHHHHHHHHHTSHHHHHHHHTT~SS~EE~STT~~~TT~~HHHHHHHHHHHT~SEEE~~HHHHS~HHHHHHHHHHHHHHHH~~SHHHHHHHHHHHHHHHHHH~~

G P I T F G S N Y S D E A P K A A F A S L M Q Q A T T S T T V P V T V N T T D H N T F Q N N I S N Y L Q G T P D S L A T W F A G Y R L Q F F A A Q G L L T P I D D V W D K I G G T F N D A A K S L S K G L D G H Y Y L V P L Y N Y P W V V F Y N K S V F Q S K G Y E V P A S W E A F I A L A R K M Q S D G L V P L A F A D K D G W P A L G T F D I L N L R I N G Y D Y H I K L M K H E V P W T D P G V T K V F D Q W R E L A A Y Q Q K G A N G R T W Q D A A K A L E N K Q A G M M F Q G S N Q V A A N Y S A K N L P D L D F F V F P A I N P Q Y G T D Y M D A P T D G F I L P K K G K N A A A A K K V L Q Y I G T A E A E A A F L K T D H W D V G L A N G L I A P T Y N D I Q K K S V A E I G K C K S V S Q F M K R D T V P D M A N A M I K L I Q Q F I D Q P T P E T I A T V Q K S A E D Q A K T I F R

AH

UNSTRUCTURED

1W84

ERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLD

~~~~EEEEE~SS~EEEEETTEEEEEEES~~SSEEEEEEEETTTTEEEEEEEESSTTSSHHHHHHHHHHHHHHHH~~~TTB~~~SEEE~S~SSSSS~~~~EEEEE~~~EEHHHHHHHS~~~HHHHHHHHHHHHHHHHHHHHTT~~~~~~~GGGEEE~TT~~EEE~~~S~S~~~TTTTSSS~HHHHTS~HHHHTT~S~~~TTHHHHHHHHHHHHHHHSS~S~~~SSHHHHHHHHHHHH~~~~HHHHHH~~~HHHHHHHHTS~~~~~~~HHHHSTT~~HHHHHHHHHHS~SSGGGS~~HHHHHTSGGGTTT~~TTS~~~~~~~~~GGGG~~~~HHHHHHHHHHHHHT~~~~~~~

E R P T F Y R Q E L N K T I W E V P E R Y Q N L S P V G S G A Y G S V C A A F D T K T G L R V A V K K L S R P F Q S I I H A K R T Y R E L R L L K H M K H E N V I G L L D V F T P A R S L E E F N D V Y L V T H L M G A D L N N I V K C Q K L T D D H V Q F L I Y Q I L R G L K Y I H S A D I I H R D L K P S N L A V N E D C E L K I L D F G L A R H T D D E M T G Y V A T R W Y R A P E I M L N W M H Y N Q T V D I W S V G C I M A E L L T G R T L F P G T D H I D Q L K L I L R L V G T P G A E L L K K I S S E S A R N Y I Q S L T Q M P K M N F A N V F I G A N P L A V D L L E K M L V L D S D K R I T A A Q A L A H A Y F A Q Y H D P D D E P V A D P Y D Q S F E S R D L L I D E W K S L T Y D E V I S F V P P P L D

AH

UNSTRUCTURED

4P6E

ILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEIEILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEIE

~~~S~EEGGGGT~~~~~~B~TTSB~HHHHHHHHHHHHHHHHHHS~~~~B~HHHHHHHS~GGGT~~TTB~~~HHHHHHHHHHHT~EEBTTTS~~~SS~~~~~~~GGGEEE~~~EEEE~~TT~HHHHHHHHHHT~~EEEEE~~~SHHHHT~~SS~B~~TT~~S~~~EEEEEEEEEEETTEEEEEEE~SB~TTSTBTTEEEEE~SSSSGGGTTTS~EEEE~~~~~S~EEGGGGT~~~~~~B~TTS~~HHHHHHHHHHHHHHHHHHS~~~~B~HHHHHHHS~GGGT~~GGG~~~HHHHHHHHHHHT~EEBTTTS~~~SS~~~~~~~GGGEEE~~~EEEE~~TT~HHHHHHHHHHT~~EEEEE~~~SHHHHT~~SSEE~~TT~~S~~~EEEEEEEEEEETTEEEEEEE~SB~TTSTBTTEEEEE~SSSSGGGTTTS~EEEE~~

I L P D S V D W R E K G C V T E V K Y Q G S C G A C W A F S A V G A L E A Q L K L K T G K L V S L S A Q N L V D C S T E K Y G N K G C N G G F M T T A F Q Y I I D N K G I D S D A S Y P Y K A M D Q K C Q Y D S K Y R A A T C S K Y T E L P Y G R E D V L K E A V A N K G P V S V G V D A R H P S F F L Y R S G V Y Y E P S C T Q N V N H G V L V V G Y G D L N G K E Y W L V K N S W G H N F G E E G Y I R M A R N K G N H C G I A S F P S Y P E I E I L P D S V D W R E K G C V T E V K Y Q G S C G A C W A F S A V G A L E A Q L K L K T G K L V S L S A Q N L V D C S T E K Y G N K G C N G G F M T T A F Q Y I I D N K G I D S D A S Y P Y K A M D Q K C Q Y D S K Y R A A T C S K Y T E L P Y G R E D V L K E A V A N K G P V S V G V D A R H P S F F L Y R S G V Y Y E P S C T Q N V N H G V L V V G Y G D L N G K E Y W L V K N S W G H N F G E E G Y I R M A R N K G N H C G I A S F P S Y P E I E

UNSTRUCTURED

AH

1PXI

MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRTEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL

~TTEEEEEEEEE~SSSEEEEEEETTT~~EEEEEEE~~~S~~HHHHHHHHHHTT~~~TTB~~EEEEEEETTEEEEEEE~~SEEHHHHHHTTTTT~~~HHHHHHHHHHHHHHHHHHHHTT~~~S~~~GGGEEE~TTS~EEE~STTHHHHS~~~SB~TT~~B~~~TT~~HHHHTT~SS~~THHHHHHHHHHHHHHHHSS~S~~~SSHHHHHHHHHHHH~~~~TTTSTTGGGSTT~~TTS~~~~~~~HHHHSTT~~HHHHHHHHHHT~SSTTTS~~HHHHHTSGGGTT~~~~~~~~~~

M E N F Q K V E K I G E G T Y G V V Y K A R N K L T G E V V A L K K I R T E G V P S T A I R E I S L L K E L N H P N I V K L L D V I H T E N K L Y L V F E F L H Q D L K K F M D A S A L T G I P L P L I K S Y L F Q L L Q G L A F C H S H R V L H R D L K P Q N L L I N T E G A I K L A D F G L A R A F G V P V R T Y T H E V V T L W Y R A P E I L L G C K Y Y S T A V D I W S L G C I F A E M V T R R A L F P G D S E I D Q L F R I F R T L G T P D E V V W P G V T S M P D Y K P S F P K W A R Q D F S K V V P P L D E D G R S L L S Q M L H Y D P N K R I S A K A A L A H P F F Q D V T K P V P H L R L

AH

UNSTRUCTURED

3I43

SQTVHFQGNPVTVANSIPQAGSKAQTFTLVAKDLSDVTLGQFAGKRKVLNIFPSIDTGVCAASVRKFNQLATEIDNTVVLCISADLPFAQSRFCGAEGLNNVITLSTFRNAEFLQAYGVAIADGPLKGLAARAVVVIDENDNVIFSQLVDEITTEPDYEAALAVLKASQTVHFQGNPVTVANSIPQAGSKAQTFTLVAKDLSDVTLGQFAGKRKVLNIFPSIDTGVCAASVRKFNQLATEIDNTVVLCISADLPFAQSRFCGAEGLNNVITLSTFRNAEFLQAYGVAIADGPLKGLAARAVVVIDENDNVIFSQLVDEITTEPDYEAALAVLKA

~EEEEETTEEEEE~S~~~~TT~B~~~~EEE~TTS~EEEGGGGTTSEEEEEE~S~S~SS~~~HHHHHHHHHHHTSTTEEEEEEESS~HHHHTT~SSSTT~TTEEEEE~TT~THHHHHTT~BB~SSTTTTSB~~EEEEE~TTSBEEEEEE~SBTTS~~~HHHHHHHHH~~EEEEETTEEEEE~S~~~~TTSB~~~~EEE~TTS~EEEGGGGTTSEEEEEE~S~S~SS~~~HHHHHHHHHHHHSTTEEEEEEESS~HHHHTT~STTTT~TTEEEEE~TT~THHHHHTT~BB~SSTTTTSB~~EEEEE~TTSBEEEEEE~SBTTS~~~HHHHHHHHH~

S Q T V H F Q G N P V T V A N S I P Q A G S K A Q T F T L V A K D L S D V T L G Q F A G K R K V L N I F P S I D T G V C A A S V R K F N Q L A T E I D N T V V L C I S A D L P F A Q S R F C G A E G L N N V I T L S T F R N A E F L Q A Y G V A I A D G P L K G L A A R A V V V I D E N D N V I F S Q L V D E I T T E P D Y E A A L A V L K A S Q T V H F Q G N P V T V A N S I P Q A G S K A Q T F T L V A K D L S D V T L G Q F A G K R K V L N I F P S I D T G V C A A S V R K F N Q L A T E I D N T V V L C I S A D L P F A Q S R F C G A E G L N N V I T L S T F R N A E F L Q A Y G V A I A D G P L K G L A A R A V V V I D E N D N V I F S Q L V D E I T T E P D Y E A A L A V L K A

BS

UNSTRUCTURED

3V9B

FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQ

~~S~~HHHHHHHHHGGGTTSTT~~HHHHHHHTTS~HHHHHHHHHHHHTTHHHHTT~~HHHHHHHHHHHHHTS~TT~SSSSHHHHHHHHHHHHHHHT~GGGTTTS~HHHHHHHHHHHHHTTTT~~SS~HHHHHHTT~HHHHHTTTSSHHHHHHHHHHHHGGGSTT~~TTTTS~HHHHHHHHHHHHHHHHTTSGGGHHHHHHHHHHHHHT~~B~TTS~B~~~SHHHHHHHHHHHHHHHHT~GGGS~HHHHHHHHHHHHHHHHHHHHHHHHTT~~~~GGG~SSS~~HHHHHHHHHHHTHHHHHHHHHHHTTTTTHHHHHHHHHHHHHHHHH~~~~HHHHHHHHHGGGTTSTT~~HHHHHHHTTS~HHHHHHHHHHHHTTHHHHHT~~HHHHHHHHHHHHHTS~TT~SSSSHHHHHHHHHHHHHHHT~GGGTTTS~HHHHHHHHHHHHHTTTT~~SS~HHHHHHTT~HHHHHTTTSSHHHHHHHHHHHHGGGSTT~~TTTTS~HHHHHHHHHHHHHHHHTT~GGGHHHHHHHHHHHHHT~~B~TT~~B~~~SHHHHHHHHHHHHHHHHT~GGGS~HHHHHHHHHHHHHHHHHHHHHHHHTT~~~~GGG~TTS~~HHHHHHHHHHHTHHHHHHHHHHHTTTTTHHHHHHHHHHHHHHHHT~~~~HHHHHHHHTTTTSTT~~HHHHHHHTTS~HHHHHHHHHHHHTTHHHHTT~~HHHHHHHHHHHHHTS~TTSSSSSHHHHHHHHHHHHHHHT~GGGTTTS~HHHHHHHHHHHHHTTTT~~SS~HHHHHHTT~HHHHHTTTSSHHHHHHHHHHHHGGGSTT~~TEETS~HHHHHHHHHHHHHHHHTT~GGGHHHHHHHHHHHHHT~~B~SSS~B~~~SHHHHHHHHHHHHHHHHT~GGGS~HHHHHHHHHHHHHHHHHHHHHHHHTT~~~~TTT~TTS~~HHHHHHHHHHHTHHHHHHHHHHHTTTTTHHHHHHHHHHHHHHHTT~~~~~HHHHHHHGGGTTSTT~~HHHHHHHTTS~HHHHHHHHHHHHTTHHHHTT~~HHHHHHHHHHHHHTS~TTSSSSSHHHHHHHHHHHHHHHT~GGGTTTS~HHHHHHHHHHHHHTTTT~~SS~HHHHHHTT~HHHHHTTTSSHHHHHHHHHHHHGGGSTT~~TTTTS~HHHHHHHHHHHHHHHHTTSGGGHHHHHHHHHHHHHT~~B~TTSSB~~~SHHHHHHHHHHHHHHHHT~GGGS~HHHHHHHHHHHHHHHHHHHHHHHHTT~~~~TT~~TTS~~HHHHHHHHHHHTHHHHHHHHHHHTTTTTHHHHHHHHHHHHHHHTT~~~

F G V K T E Q E D V L A K E L E D V N K W G L H V F R I A E L S G N R P L T V I M H T I F Q E R D L L K T F K I P V D T L I T Y L M T L E D H Y H A D V A Y H N N I H A A D V V Q S T H V L L S T P A L E A V F T D L E I L A A I F A S A I H D V D H P G V S N Q F L I N T N S E L A L M Y N D S S V L E N H H L A V G F K L L Q E E N C D I F Q N L T K K Q R Q S L R K M V I D I V L A T D M S K H M N L L A D L K T M V E T K K V T S S G V L L L D N Y S D R I Q V L Q N M V H C A D L S N P T K P L Q L Y R Q W T D R I M E E F F R Q G D R E R E R G M E I S P M C D K H N A S V E K S Q V G F I D Y I V H P L W E T W A D L V H P D A Q D I L D T L E D N R E W Y Q S T I P Q T E Q E D V L A K E L E D V N K W G L H V F R I A E L S G N R P L T V I M H T I F Q E R D L L K T F K I P V D T L I T Y L M T L E D H Y H A D V A Y H N N I H A A D V V Q S T H V L L S T P A L E A V F T D L E I L A A I F A S A I H D V D H P G V S N Q F L I N T N S E L A L M Y N D S S V L E N H H L A V G F K L L Q E E N C D I F Q N L T K K Q R Q S L R K M V I D I V L A T D M S K H M N L L A D L K T M V E T K K V T S S G V L L L D N Y S D R I Q V L Q N M V H C A D L S N P T K P L Q L Y R Q W T D R I M E E F F R Q G D R E R E R G M E I S P M C D K H N A S V E K S Q V G F I D Y I V H P L W E T W A D L V H P D A Q D I L D T L E D N R E W Y Q S T I P Q Q E D V L A K E L E D V N K W G L H V F R I A E L S G N R P L T V I M H T I F Q E R D L L K T F K I P V D T L I T Y L M T L E D H Y H A D V A Y H N N I H A A D V V Q S T H V L L S T P A L E A V F T D L E I L A A I F A S A I H D V D H P G V S N Q F L I N T N S E L A L M Y N D S S V L E N H H L A V G F K L L Q E E N C D I F Q N L T K K Q R Q S L R K M V I D I V L A T D M S K H M N L L A D L K T M V E T K K V T S S G V L L L D N Y S D R I Q V L Q N M V H C A D L S N P T K P L Q L Y R Q W T D R I M E E F F R Q G D R E R E R G M E I S P M C D K H N A S V E K S Q V G F I D Y I V H P L W E T W A D L V H P D A Q D I L D T L E D N R E W Y Q S T I P Q E Q E D V L A K E L E D V N K W G L H V F R I A E L S G N R P L T V I M H T I F Q E R D L L K T F K I P V D T L I T Y L M T L E D H Y H A D V A Y H N N I H A A D V V Q S T H V L L S T P A L E A V F T D L E I L A A I F A S A I H D V D H P G V S N Q F L I N T N S E L A L M Y N D S S V L E N H H L A V G F K L L Q E E N C D I F Q N L T K K Q R Q S L R K M V I D I V L A T D M S K H M N L L A D L K T M V E T K K V T S S G V L L L D N Y S D R I Q V L Q N M V H C A D L S N P T K P L Q L Y R Q W T D R I M E E F F R Q G D R E R E R G M E I S P M C D K H N A S V E K S Q V G F I D Y I V H P L W E T W A D L V H P D A Q D I L D T L E D N R E W Y Q S T I P Q

AH

T

3ISX

HHHHKELIRKLTEAFGPSGREEEVRSIILEELEGHIDGHRIDGLGNLIVWKGSGEKKVILDAHIDEIGVVVTNVDDKGFLTIEPVGGVSPYLLGKRIRFENGTIGVVGEGETTEERQENVRKLSFDKLFIDIGANSREEAQKCPIGSFGVYDSGFVEVSGKYVSKADDRIGCAVIVEVFKRIKPAVTLYGVFSVQEEVGLVGASVAGYGVPADEAIAIDVTDSADTPKAIKRHARLSGGPALKVKDRASISSKRILENLIEIAEKFDIKYQEVLTFGGTNAGYQRTREGIPSATVSIPTRYVHSPSEIAPDDVEATVDLLIRYLGA

~~~~~HHHHHHHHS~~BTT~~HHHHHHHHHHHTTT~SEEEE~TT~~EEEEE~~~SSEEEEEEE~~B~EEEEEEE~TTS~EEEEEESS~~~~~TT~EEEETTS~EEEE~~~~SHHHHHHHHHT~~GGG~~EE~S~SSHHHHH~~~TT~EEEES~~~EEETTEEE~~~~~HHHHHHHHHHHHH~~~SSEEEEEEE~~~~TTS~~STTTGGG~~~SEEEEEEEEE~~~STT~~~TT~~TTS~~EEE~BTT~~HHHHHHHHHHHHHHHHTT~~~~~~~B~~~S~~~HHHHTSS~~EEEEEEEESSTTSTT~~~HHHHHHHHHHHHHHH~~

H H H H K E L I R K L T E A F G P S G R E E E V R S I I L E E L E G H I D G H R I D G L G N L I V W K G S G E K K V I L D A H I D E I G V V V T N V D D K G F L T I E P V G G V S P Y L L G K R I R F E N G T I G V V G E G E T T E E R Q E N V R K L S F D K L F I D I G A N S R E E A Q K C P I G S F G V Y D S G F V E V S G K Y V S K A D D R I G C A V I V E V F K R I K P A V T L Y G V F S V Q E E V G L V G A S V A G Y G V P A D E A I A I D V T D S A D T P K A I K R H A R L S G G P A L K V K D R A S I S S K R I L E N L I E I A E K F D I K Y Q E V L T F G G T N A G Y Q R T R E G I P S A T V S I P T R Y V H S P S E I A P D D V E A T V D L L I R Y L G A

UNSTRUCTURED

AH

3VP7

INIFNATFKISHSGPFATINGLRLGSIPESVVPWKEINAALGQLILLLATINKNLKINLVDYELQPMGSFSKIKKRMDWLILPVYYDETKFDKSLETTLEIISEITRQLSTIASSLELPYIMNKDKINGLSVKLHGSSPNLEWTTAMKFLLTNVKWLLAFSSNLLS

~~TTTTT~~EEEETTEEEETTEEE~~BTTB~~~HHHHHHHHHHHHHHHHHHHHHTT~~~SSEEEE~~GGG~EEEEE~~EEEEESS~~~~HHHHHHHHHHHHHHHHHHHHHHHHH~~~~SS~EETTEETTEES~~TTS~~~HHHHHHHHHHHHHHHHHHHHHHHHH~

I N I F N A T F K I S H S G P F A T I N G L R L G S I P E S V V P W K E I N A A L G Q L I L L L A T I N K N L K I N L V D Y E L Q P M G S F S K I K K R M D W L I L P V Y Y D E T K F D K S L E T T L E I I S E I T R Q L S T I A S S L E L P Y I M N K D K I N G L S V K L H G S S P N L E W T T A M K F L L T N V K W L L A F S S N L L S

AH

UNSTRUCTURED

1G27

SVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVEKLDRLSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVEKLDRLSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVEKLDRL

~~B~~~~TT~GGGG~B~B~~S~~~HHHHHHHHHHHHHHHHHT~SEEEGGGGT~~BSEEEE~~~SSS~~~EEEEEEEEEEEE~~B~~EEE~TTSTT~EEE~~B~SEEEEEEE~TTS~EEEEEE~HHHHHHHHHHHHHTBT~~GGGGS~HHHHHHHHHHHHHHHH~~~B~~~~TT~GGGG~~~B~~S~~~HHHHHHHHHHHHHHHHHT~SEEEGGGGT~~BSEEEE~~~TTS~~~EEEEEEEEEEEE~~B~~EEEETTEEEEEEE~~B~SEEEEEEE~TT~~EEEEEE~HHHHHHHHHHHHHTTT~~GGGGS~HHHHHHHHHHHHHHHH~~~~~~~~TT~GGGG~~~B~~S~~~HHHHHHHHHHHHHHHHHT~SEEEGGGGT~~BSEEEE~~~TTS~~~EEEEEEEEEEEE~~B~~EEEETTEEEEEEE~~B~SEEEEEEE~TTS~EEEEEE~HHHHHHHHHHHHHHTT~~GGGGS~HHHHHHHHHHHHHHH~~

S V L Q V L H I P D E R L R K V A K P V E E V N A E I Q R I V D D M F E T M Y A E E G I G L A A T Q V D I H Q R I I V I D V S E N R D E R L V L I N P E L L E K S G E T G I E E G C L S I P E Q R A L V P R A E K V K I R A L D R D G K P F E L E A D G L L A I C I Q H E M D H L V G K L F M D Y L S P L K Q Q R I R Q K V E K L D R L S V L Q V L H I P D E R L R K V A K P V E E V N A E I Q R I V D D M F E T M Y A E E G I G L A A T Q V D I H Q R I I V I D V S E N R D E R L V L I N P E L L E K S G E T G I E E G C L S I P E Q R A L V P R A E K V K I R A L D R D G K P F E L E A D G L L A I C I Q H E M D H L V G K L F M D Y L S P L K Q Q R I R Q K V E K L D R L S V L Q V L H I P D E R L R K V A K P V E E V N A E I Q R I V D D M F E T M Y A E E G I G L A A T Q V D I H Q R I I V I D V S E N R D E R L V L I N P E L L E K S G E T G I E E G C L S I P E Q R A L V P R A E K V K I R A L D R D G K P F E L E A D G L L A I C I Q H E M D H L V G K L F M D Y L S P L K Q Q R I R Q K V E K L D R L

AH

BS

1U3J

NLKIVRMDRTAGCVTGGEEIMLLCDKVQKDDIQIRFYEEVWEGFGDFSPTDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDLETSEPKPFLYYPE

~~~EEEHS~SEEETT~~~EEEEEES~~~TTS~EEEEEE~~EEEE~B~~GGGEETTTEEEEE~~~~S~TT~SS~EEEEEEEE~TTT~~B~~~EEEEEE~~

N L K I V R M D R T A G C V T G G E E I M L L C D K V Q K D D I Q I R F Y E E V W E G F G D F S P T D V H R Q F A I V F K T P K Y K D V N I T K P A S V F V Q L R R K S D L E T S E P K P F L Y Y P E

BS

UNSTRUCTURED

4S3L

DDNSAITKANGENNAVVKINKTLNIAEGITTPTATFTFKFTEKTGQSSNGAPYQTGVAIPDRNVEYNKNDHPTADKIQKATEDIFSGVAYGHAGEYVYDVAEAKTGWQAITKNGKTIDAMRYDKRTYEMHVIVKNKVNGGVYISSVYFKENNKSNAPKVESSEQGVYNLFDNTYTKDASKEPNPDDPSQVDPNAKALTITKKVDGASGDKTRDFQFHIKIQLPSTNKTAETPVTNIIVKHGSKSEVLAVVTPADTVEYNFTLKDGETFTVEQLPAGSKYTVTETGVAGYTDSSIYTTNGAEQTSQGQKNVDFTLTDILIGEKKNDNKVTNKIDDVTPTDDNSAITKANGENNAVVKINKTLNIAEGITTPTATFTFKFTEKTGQSSNGAPYQTGVAIPDRNVEYNKNDHPTADKIQKATEDIFSGVAYGHAGEYVYDVAEAKTGWQAITKNGKTIDAMRYDKRTYEMHVIVKNKVNGGVYISSVYFKENNKSNAPKVESSEQGVYNLFDNTYTKDASKEPNPDDPSQVDPNAKALTITKKVDGASGDKTRDFQFHIKIQLPSTNKTAETPVTNIIVKHGSKSEVLAVVTPADTVEYNFTLKDGETFTVEQLPAGSKYTVTETGVAGYTDSSIYTTNGAEQTSQGQKNVDFTLTDILIGEKKNDNKVTNKIDDVTPT

~~S~SSB~~STTS~~~~EEEEEEEE~TT~~~~~EEEEEEEEEE~~B~TTS~B~~~~~~~~~EEEEE~TT~~~BTTEEEEE~S~TTTT~~~~S~EEEEEEEEE~S~SB~~~EETTEE~EEEE~~~~EEEEEEEEEE~TTS~EEEEEEEEEETT~TT~~B~~~SBTTEE~~~EEEEEEBTT~~~~TT~TTS~~SS~~SEEEEEEEESTT~~SSS~EEEEEEEE~~GGGGSSS~~~EEEEEESTT~EEEEE~BTTTTEEEEEEEE~TT~EEEE~~~BTTEEEEEEE~~~TTEEEEEEEEETTEEEEEE~~SSS~EEEEEEEE~SS~~EEEEEEEE~~~~~~~~S~SSB~~STTS~~~~EEEEEEEE~TT~~~~~EEEEEEEEEE~~B~TTS~B~~~~~~~~~EEEEE~TT~~~BTTEEEEE~S~TTTT~HH~S~EEEEEEEEE~S~SB~~~EETTEE~EEEE~~~~EEEEEEEEEE~TTSSEEEEEEEEEETTSTT~~B~~~SBTTEE~~~EEEEEEBTTS~~STT~TTS~~SS~~SEEEEEEEESTT~~SSS~EEEEEEEE~~GGGGSSS~~~EEEEEESTT~EEEEE~BTTTTEEEEEEEE~TT~EEEE~~~BTTEEEEEEE~~~TTEEEEEEEEETTEEEEEE~~SSS~EEEEEEEE~SS~~EEEEEEEE~~~~~~

D D N S A I T K A N G E N N A V V K I N K T L N I A E G I T T P T A T F T F K F T E K T G Q S S N G A P Y Q T G V A I P D R N V E Y N K N D H P T A D K I Q K A T E D I F S G V A Y G H A G E Y V Y D V A E A K T G W Q A I T K N G K T I D A M R Y D K R T Y E M H V I V K N K V N G G V Y I S S V Y F K E N N K S N A P K V E S S E Q G V Y N L F D N T Y T K D A S K E P N P D D P S Q V D P N A K A L T I T K K V D G A S G D K T R D F Q F H I K I Q L P S T N K T A E T P V T N I I V K H G S K S E V L A V V T P A D T V E Y N F T L K D G E T F T V E Q L P A G S K Y T V T E T G V A G Y T D S S I Y T T N G A E Q T S Q G Q K N V D F T L T D I L I G E K K N D N K V T N K I D D V T P T D D N S A I T K A N G E N N A V V K I N K T L N I A E G I T T P T A T F T F K F T E K T G Q S S N G A P Y Q T G V A I P D R N V E Y N K N D H P T A D K I Q K A T E D I F S G V A Y G H A G E Y V Y D V A E A K T G W Q A I T K N G K T I D A M R Y D K R T Y E M H V I V K N K V N G G V Y I S S V Y F K E N N K S N A P K V E S S E Q G V Y N L F D N T Y T K D A S K E P N P D D P S Q V D P N A K A L T I T K K V D G A S G D K T R D F Q F H I K I Q L P S T N K T A E T P V T N I I V K H G S K S E V L A V V T P A D T V E Y N F T L K D G E T F T V E Q L P A G S K Y T V T E T G V A G Y T D S S I Y T T N G A E Q T S Q G Q K N V D F T L T D I L I G E K K N D N K V T N K I D D V T P T

BS

UNSTRUCTURED

1K86

TYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGARCKTLLEKPKLFFIQACRGTELDDGIQKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGARCKTLLEKPKLFFIQACRGTELDDGIQKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ

~~B~~~~SSEEEEEEEEE~~~~~TTT~~~~~TTHHHHHHHHHHHHHHHT~EEEEEES~~HHHHHHHHHHHHHS~~TTEEEEEEEEEEEB~SSEEEETTEEEEHHHHHHTTSGGGGGGGTTS~EEEEEEEE~~SS~~~~~~~~~~SSSEEEEESS~TT~~~~~~TTT~~HHHHHHHHHHHHHTTTS~HHHHHHHHHHHHHTT~~~~~SSTTTSS~~~~~EEEE~~SSB~~S~~~~B~~~~SSEEEEEEEEE~~~~~GGG~~~~~TTHHHHHHHHHHHHHHTT~EEEEEES~~HHHHHHHHHHHHTS~~TTEEEEEEEEEEEEETTEEE~SSSEEEHHHHHGGGSGGGGGGGTTS~EEEEEEEE~~~~~~~~~~~~~~SSSEEEEESS~TTS~~~~~TTT~~HHHHHHHHHHHHHTTTS~HHHHHHHHHHHHH~~~~~~~SSTTSSS~~~~~EEEE~~SSB~~S~~

T Y Q Y N M N F E K L G K C I I I N N K N F D K V T G M G V R N G T D K D A E A L F K C F R S L G F D V I V Y N D C S C A K M Q D L L K K A S E E D H T N A A C F A C I L L S H G E E N V I Y G K D G V T P I K D L T A H F R G A R C K T L L E K P K L F F I Q A C R G T E L D D G I Q K I P V E A D F L F A Y S T V P G Y Y S W R S P G R G S W F V Q A L C S I L E E H G K D L E I M Q I L T R V N D R V A R H F E S Q S D D P H F H E K K Q I P C V V S M L T K E L Y F S Q T Y Q Y N M N F E K L G K C I I I N N K N F D K V T G M G V R N G T D K D A E A L F K C F R S L G F D V I V Y N D C S C A K M Q D L L K K A S E E D H T N A A C F A C I L L S H G E E N V I Y G K D G V T P I K D L T A H F R G A R C K T L L E K P K L F F I Q A C R G T E L D D G I Q K I P V E A D F L F A Y S T V P G Y Y S W R S P G R G S W F V Q A L C S I L E E H G K D L E I M Q I L T R V N D R V A R H F E S Q S D D P H F H E K K Q I P C V V S M L T K E L Y F S Q

UNSTRUCTURED

AH

1INV

EPEWTYPRLSCQGSTFQKALLISPHRFGEIKGNSAPLIIREPFVACGPKECRHFALTHYAAQPGGYYNGTRKDRNKLRHLVSVKLGKIPTVENSIFHMAAWSGSACHDGREWTYIGVDGPDNDALVKIKYGEAYTDTYHSYAHNILRTQESACNCIGGDCYLMITDGSASGISKCRFLKIREGRIIKEILPTGRVEHTEECTCGFASNKTIECACRDNSYTAKRPFVKLNVETDTAEIRLMCTKTYLDTPRPDDGSIAGPCESNGDKWLGGIKGGFVHQRMASKIGRWYSRTMSKTNRMGMELYVRYDGDPWTDSDALTLSGVMVSIEEPGWYSFGFEIKDKKCDVPCIGIEMVHDGGKDTWHSAATAIYCLMGSGQLLWDTVTGVDMAL

~~~~~~~HHH~SBS~EEEEEEE~GGGG~~TTS~~~BEEEEEEEEEE~SS~EEEEEEEEEEESSSS~~TTTT~S~~SS~EEEEEETTS~~BTTT~EEEEE~SEEEEEE~SS~EEEEEEES~GGG~EEEEEETTEEEEEEE~SSSS~~EE~SS~~EEETTEEEEEEEEE~TTS~EEEEEEEEETTEEEEEE~~EES~SB~EEEEEEESSSSEEEEEEE~SSS~SS~EEEEEETTTTEEEEEE~~~SS~~SSS~~STT~S~SSTT~~~S~~~~~~~~~EEEEE~SS~EEEEEEE~SSSSSSEEEEEEEEESS~TTT~~S~~EEEEEEEEEEEE~~~EEEEEEE~SSSEEEEEEEEEEE~~~TTS~~EEEEEEEEE~BSS~~~~~~~~~~~TT~

E P E W T Y P R L S C Q G S T F Q K A L L I S P H R F G E I K G N S A P L I I R E P F V A C G P K E C R H F A L T H Y A A Q P G G Y Y N G T R K D R N K L R H L V S V K L G K I P T V E N S I F H M A A W S G S A C H D G R E W T Y I G V D G P D N D A L V K I K Y G E A Y T D T Y H S Y A H N I L R T Q E S A C N C I G G D C Y L M I T D G S A S G I S K C R F L K I R E G R I I K E I L P T G R V E H T E E C T C G F A S N K T I E C A C R D N S Y T A K R P F V K L N V E T D T A E I R L M C T K T Y L D T P R P D D G S I A G P C E S N G D K W L G G I K G G F V H Q R M A S K I G R W Y S R T M S K T N R M G M E L Y V R Y D G D P W T D S D A L T L S G V M V S I E E P G W Y S F G F E I K D K K C D V P C I G I E M V H D G G K D T W H S A A T A I Y C L M G S G Q L L W D T V T G V D M A L

BS

UNSTRUCTURED

3IOM

DPDELARRAAQVIADRTGIGEHDVAVVLGSGWLPAVAALGSPTTVLPQAELPGFVPPTAAGHAGELLSVPIGAHRVLVLAGRIHAYEGHDLRYVVHPVRAARAAGAQIMVLTNAAGGLRADLQVGQPVLISDHLNLTARSPLVGGEFVDLTDAYSPRLRELARQSDPQLAEGVYAGLPGPHYETPAEIRMLQTLGADLVGMSTVHETIAARAAGAEVLGVSLVTNLAAGITGEPLSHAEVLAAGAASATRMGALLADVIARFDPDELARRAAQVIADRTGIGEHDVAVVLGSGWLPAVAALGSPTTVLPQAELPGFVPPTAAGHAGELLSVPIGAHRVLVLAGRIHAYEGHDLRYVVHPVRAARAAGAQIMVLTNAAGGLRADLQVGQPVLISDHLNLTARSPLVGGEFVDLTDAYSPRLRELARQSDPQLAEGVYAGLPGPHYETPAEIRMLQTLGADLVGMSTVHETIAARAAGAEVLGVSLVTNLAAGITGEPLSHAEVLAAGAASATRMGALLADVIARF

~HHHHHHHHHHHHHHHHS~S~~~EEEE~~TT~GGGHHHH~~~SEEEEGGGSTTSS~SSS~~~~~EEEEEEETTEEEEEEES~~~GGG~S~HHHHHHHHHHHHHTT~SEEEEEEEEEE~STT~~TT~EEEEEEEEE~SS~~S~~SS~~~~~TTSS~HHHHHHHHHH~TT~EEEEEEE~~~SS~~~HHHHHHHHHHT~SEEESSSHHHHHHHHHTT~EEEEEEEEEEE~TTSS~~~~~HHHHHHHHHHHHHHHHHHHHHHHHH~~HHHHHHHHHHHHHHHHT~S~~~EEEEE~TTTGGGHHHH~~~SEEEEGGGSTTTS~SS~~S~~~EEEEEEETTEEEEEEE~~~~GGG~~~HHHHSHHHHHHHHTT~SEEEEEEEEEE~STT~~TT~EEEEEEEEE~SS~~S~~SS~~~~~TTSS~HHHHHHHHHH~TT~EEEEEEE~~~SS~~~HHHHHHHHHTT~SEEESSSHHHHHHHHHTT~EEEEEEEEEEE~TTSSS~~~~HHHHHHHHHHHHHHHHHHHHHHHHH~

D P D E L A R R A A Q V I A D R T G I G E H D V A V V L G S G W L P A V A A L G S P T T V L P Q A E L P G F V P P T A A G H A G E L L S V P I G A H R V L V L A G R I H A Y E G H D L R Y V V H P V R A A R A A G A Q I M V L T N A A G G L R A D L Q V G Q P V L I S D H L N L T A R S P L V G G E F V D L T D A Y S P R L R E L A R Q S D P Q L A E G V Y A G L P G P H Y E T P A E I R M L Q T L G A D L V G M S T V H E T I A A R A A G A E V L G V S L V T N L A A G I T G E P L S H A E V L A A G A A S A T R M G A L L A D V I A R F D P D E L A R R A A Q V I A D R T G I G E H D V A V V L G S G W L P A V A A L G S P T T V L P Q A E L P G F V P P T A A G H A G E L L S V P I G A H R V L V L A G R I H A Y E G H D L R Y V V H P V R A A R A A G A Q I M V L T N A A G G L R A D L Q V G Q P V L I S D H L N L T A R S P L V G G E F V D L T D A Y S P R L R E L A R Q S D P Q L A E G V Y A G L P G P H Y E T P A E I R M L Q T L G A D L V G M S T V H E T I A A R A A G A E V L G V S L V T N L A A G I T G E P L S H A E V L A A G A A S A T R M G A L L A D V I A R F

AH

BS

3ZWZ

NPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIENSNTTFLTPVATGNQYLKDGGFAFPPTEPLMSPMTLDEMRHFYKDNKYVKNLDELTLCSRHAGNMIPDNDKNSNYKYPAVYDDKDKKCHILYIAAQENNGPRYCNKDESKRNSMFCFRPAKDISFQNYTYLSKNVVDNWEKVCPRKNLQNAKFGLWVDGNCEDIPHVNEFPAIDLFECNKLVFELSASDQPDRYKSHGKGYNWGNYNTETQKCEIFNVKPTCLINNSSYIATTALSHPIEVEAAATQQAKDIGAGPVASCFTTRMSPPQQICLNSVVNTAL

~TTTTGGGGG~HHHHT~S~SSB~~~EEEEETTEEEEE~~~SS~EETEEEEETT~~~~TTSB~~BTT~~GGG~~SB~~~EES~~SSEEHHHHHHHTTT~TTTTT~~HHHHHHHHHTTEEETT~TT~~~~~~EEEETTTTEEEEBS~~~~~B~STTT~~~~TT~TTS~~~EEEEE~GGGTTEEEE~TT~~TTHHHHS~~SEEEEEEEEEEETTEEEE~S~~EEEE~SSHHHHHHHHHHHS~B~~~~TT~~TT~SS~EEEEETTTTEEEEE~S~~~EEEEEEEEEEEESSS~SS~EE~~~~HHHHHTT~~~~~SEEEESSSS~~EEEESS~B~TT~

N P W T E Y M A K Y D I E E V H G S G I R V D L G E D A E V A G T Q Y R L P S G K C P V F G K G I I I E N S N T T F L T P V A T G N Q Y L K D G G F A F P P T E P L M S P M T L D E M R H F Y K D N K Y V K N L D E L T L C S R H A G N M I P D N D K N S N Y K Y P A V Y D D K D K K C H I L Y I A A Q E N N G P R Y C N K D E S K R N S M F C F R P A K D I S F Q N Y T Y L S K N V V D N W E K V C P R K N L Q N A K F G L W V D G N C E D I P H V N E F P A I D L F E C N K L V F E L S A S D Q P D R Y K S H G K G Y N W G N Y N T E T Q K C E I F N V K P T C L I N N S S Y I A T T A L S H P I E V E A A A T Q Q A K D I G A G P V A S C F T T R M S P P Q Q I C L N S V V N T A L

BS

UNSTRUCTURED

2X0R

TKVSVVGAAGTVGAAAGYNIALRDIADEVVFVDIPDKEDDTVGQAADTNHGIAYDSNTRVRQGGYEDTAGSDVVVITAGIPRQPGQTRIDLAGDNAPIMEDIQSSLDEHNDDYISLTTSNPVDLLNRHLYEAGDRSREQVIGFGGRLDSARFRYVLSEEFDAPVQNVEGTILGEHGDAQVPVFSKVSVDGTDPEFSGDEKEQLLGDLQESAMDVIERKGATEWGPARGVAHMVEAILHDTGEVLPASVKLEGEFGHEDTAFGVPVSLGSNGVEEIVEWDLDDYEQDLMADAAEKLSDQYDKISTKVSVVGAAGTVGAAAGYNIALRDIADEVVFVDIPDKEDDTVGQAADTNHGIAYDSNTRVRQGGYEDTAGSDVVVITAGIPRQPGQTRIDLAGDNAPIMEDIQSSLDEHNDDYISLTTSNPVDLLNRHLYEAGDRSREQVIGFGGRLDSARFRYVLSEEFDAPVQNVEGTILGEHGDAQVPVFSKVSVDGTDPEFSGDEKEQLLGDLQESAMDVIERKGATEWGPARGVAHMVEAILHDTGEVLPASVKLEGEFGHEDTAFGVPVSLGSNGVEEIVEWDLDDYEQDLMADAAEKLSDQYDKIS

~EEEEETTTSHHHHHHHHHHHTTT~~SEEEEE~~GGGHHHHHHHHHHHHHHHTTT~~~EEEE~~GGGGSS~SEEEE~~~~~~~TT~~HHHHHHHHHHHHHHHHHHHHTT~S~~EEEE~~SSHHHHHHHHHHHS~S~TTTEEE~~HHHHHHHHHHHHHHHHT~~GGGEE~~EEE~SSSSEEE~TTT~EETTB~~~~~HHHHHHHHHHHHHHHHHHHTTT~S~~HHHHHHHHHHHHHHHTT~~EEEEEEEEEESGGG~EEEEEEEEEEEETTEEEEE~~~~~~HHHHHHHHHHHHHHHHHHHHT~~EEEEETTTSHHHHHHHHHHHTT~~SSEEEEE~~GGGHHHHHHHHHHHHHHHTTT~~~EEEE~~GGGGTT~SEEEE~~~~~~~TT~~HHHHHHHHHHHHHHHHHHTGGG~S~~EEEE~SSSHHHHHHHHHHHS~S~GGGEEE~SHHHHHHHHHHHHHHTTT~~GGGEE~~EEE~SSSSEEE~~TT~EESS~~~~~~HHHHHHHHHHHHHHHHHHHTTT~~~~HHHHHHHHHHHHHHHHT~~EEEEEEEEESSGGG~~SEEEEEEEEEETTEEEEE~~~~~~HHHHHHHHHHHHHHHHHHHTT~

T K V S V V G A A G T V G A A A G Y N I A L R D I A D E V V F V D I P D K E D D T V G Q A A D T N H G I A Y D S N T R V R Q G G Y E D T A G S D V V V I T A G I P R Q P G Q T R I D L A G D N A P I M E D I Q S S L D E H N D D Y I S L T T S N P V D L L N R H L Y E A G D R S R E Q V I G F G G R L D S A R F R Y V L S E E F D A P V Q N V E G T I L G E H G D A Q V P V F S K V S V D G T D P E F S G D E K E Q L L G D L Q E S A M D V I E R K G A T E W G P A R G V A H M V E A I L H D T G E V L P A S V K L E G E F G H E D T A F G V P V S L G S N G V E E I V E W D L D D Y E Q D L M A D A A E K L S D Q Y D K I S T K V S V V G A A G T V G A A A G Y N I A L R D I A D E V V F V D I P D K E D D T V G Q A A D T N H G I A Y D S N T R V R Q G G Y E D T A G S D V V V I T A G I P R Q P G Q T R I D L A G D N A P I M E D I Q S S L D E H N D D Y I S L T T S N P V D L L N R H L Y E A G D R S R E Q V I G F G G R L D S A R F R Y V L S E E F D A P V Q N V E G T I L G E H G D A Q V P V F S K V S V D G T D P E F S G D E K E Q L L G D L Q E S A M D V I E R K G A T E W G P A R G V A H M V E A I L H D T G E V L P A S V K L E G E F G H E D T A F G V P V S L G S N G V E E I V E W D L D D Y E Q D L M A D A A E K L S D Q Y D K I S

AH

BS

1E9E

ARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKKSDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAYTGAKENFSLDWCKQPDVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQLMKDTTLNWKMVDASKSIEAVHEDIRVLSEDAIATATEKPLKELWK

~~~~~EEEEE~STTSSHHHHHHHHHHHHHHTT~~EEEEESS~TTSHHHHHHHHHHTTSS~~~HHHHHHHHHHHHHTTHHHHHHHHHTT~EEEEES~HHHHHHHHTTSTT~~HHHHHGGGTTSB~~SEEEEEE~~HHHHTTSS~~~SSTT~SHHHHHHHHHHHHHHTT~TTS~EEEEETTS~HHHHHHHHHHHHHHHHHHHTTS~~~BTT~

A R R G A L I V L E G V D R A G K S T Q S R K L V E A L C A A G H R A E L L R F P E R S T E I G K L L S S Y L Q K K S D V E D H S V H L L F S A N R W E Q V P L I K E K L S Q G V T L V V D R Y A F S G V A Y T G A K E N F S L D W C K Q P D V G L P K P D L V L F L Q L Q L A D A A K R G A F G H E R Y E N G A F Q E R A L R C F H Q L M K D T T L N W K M V D A S K S I E A V H E D I R V L S E D A I A T A T E K P L K E L W K

AH

T

3NT7

HMNSVTVSHAPYTITYHDDWEPVMSQLVEFYNEVASWLLRDETSPIPDKFFIQLKQPLRNKRVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLTGVIDYKGYNLNIIDGVIPWNYYLSCKLGETKSHAIYWDKISKLLLQHITKHVSVLYCLGKTDFSNIPVTTIVGYHPAARDVQFEKDRSFEIINVLLELDNKAPINWAQGFIYSHMNSVTVSHAPYTITYHDDWEPVMSQLVEFYNEVASWLLRDETSPIPDKFFIQLKQPLRNKRVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLTGVIDYKGYNLNIIDGVIPWNYYLSCKLGETKSHAIYWDKISKLLLQHITKHVSVLYCLGKTDFSNIRAKPVTTIVGYHPAARDVQFEKDRSFEIINVLLELDNKAPINWAQGFIY

~EEEEE~SSTT~EEEEEGGGGGGHHHHHHHHHHHHHHHHSS~EES~GGGTTGGGGS~STT~~EEEEESS~~TTT~~SSTT~~TTS~~HHHHHHHHHHHHHH~~~~~SEE~GGGSTTEEEEESSS~EETT~TTTTHHHHHHHHHHHHHHHTTT~SEEEEE~TTT~~~~~~EEEEE~~TT~SS~HHHHHHHHHHHHHHHHHTT~~~~~GGGGEE~~~EEEEE~SSTT~EEEEEGGGHHHHHHHHHHHHHHHHHHTTS~EES~GGGTTGGGGS~STT~~EEEEESS~~SS~~~SSTT~~TTS~~HHHHHHHHHHHHHH~~~~~SEE~GGGSTTEEEEESSS~EETT~TTTTHHHHHHHHHHHHHHHTTT~SEEEEE~TTTTTT~~~~~~EEEEE~~TT~SS~HHHHHHHHHHHHHHHHHTT~~~~~GGGGEE~

H M N S V T V S H A P Y T I T Y H D D W E P V M S Q L V E F Y N E V A S W L L R D E T S P I P D K F F I Q L K Q P L R N K R V C V C G I D P Y P K D G T G V P F E S P N F T K K S I K E I A S S I S R L T G V I D Y K G Y N L N I I D G V I P W N Y Y L S C K L G E T K S H A I Y W D K I S K L L L Q H I T K H V S V L Y C L G K T D F S N I P V T T I V G Y H P A A R D V Q F E K D R S F E I I N V L L E L D N K A P I N W A Q G F I Y S H M N S V T V S H A P Y T I T Y H D D W E P V M S Q L V E F Y N E V A S W L L R D E T S P I P D K F F I Q L K Q P L R N K R V C V C G I D P Y P K D G T G V P F E S P N F T K K S I K E I A S S I S R L T G V I D Y K G Y N L N I I D G V I P W N Y Y L S C K L G E T K S H A I Y W D K I S K L L L Q H I T K H V S V L Y C L G K T D F S N I R A K P V T T I V G Y H P A A R D V Q F E K D R S F E I I N V L L E L D N K A P I N W A Q G F I Y

AH

UNSTRUCTURED

1YP6

EEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLFGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRC

~~B~TTSTT~~GGGG~EE~EEEEEEESSGGGGSTT~TT~~EEEEEEE~SSEEEEEEEEEETTEEEEEEEEEEE~SSTT~EEEESSSEEEEEEEEE~SSSEEEEEEEEEETTEEEEEEEEEESSS~~~HHHHHHHHHHHHHTT~~GGGEEE~TTS~~~

E E A S S T G R N F N V E K I N G E W H T I I L A S D K R E K I E D N G N F R L F L E Q I H V L E K S L V L K F H T V R D E E C S E L S M V A D K T E K A G E Y S V T Y D G F N T F T I P K T D Y D N F L M A H L I N E K D G E T F Q L M G L F G R E P D L S S D I K E R F A Q L C E E H G I L R E N I I D L S N A N R C

BS

UNSTRUCTURED

2ERQ

SNLTPEQQRYLNAKKYVKLFLVADYIMYLKYGRNLTAVRTRMYDIVNVITPIYHRMNIHVALVGLEIWSNTDKIIVQSSADVTLDLFAKWRATDLLSRKSHDNAQLLTGINFNGPTAGLGYLGGICNTMYSAGIVQDHSKIHHLVAIAMAHEMGHNLGMDHDKDTCTCGTRPCVMAGALSCEASFLFSDCSQKDHREFLIKNMPQCILKKPLKTDVVSPAVCGNYFVEVGEECDCGSPRTCRDPCCDATTCKLRQGAQCAEGLCCDQCRFKGAGTECRAAKDECDMADVCTGRSAECTDRFQRNGQPCKNNNGYCYNGKCPIMADQCIALFGPGATVSQDACFQFNREGNHYGYCRKEQNTKIACEPQDVKCGRLYCFPNSPENKNPCNIYYSPNDEDKGMVLPGTKCADRKACSNGQCVDVTTLTPEQQRYLNAKKYVKLFLVADYIMYLKYGRNLTAVRTRMYDIVNVITPIYHRMNIHVALVGLEIWSNTDKIIVQSSADVTLDLFAKWRATDLLSRKSHDNAQLLTGINFNGPTAGLGYLGGICNTMYSAGIVQDHSKIHHLVAIAMAHEMGHNLGMDHDKDTCTCGTRPCVMAGALSCEASFLFSDCSQKDHREFLIKNMPQCILKKPLKTDVVSPAVCGNYFVEVGEECDCGSPRTCRDPCCDATTCKLRQGAQCAEGLCCDQCRFKGAGTECRAAKDECDMADVCTGRSAECTDRFQRNGQPCKNNNGYCYNGKCPIMADQCIALFGPGATVSQDACFQFNREGNHYGYCRKEQNTKIACEPQDVKCGRLYCFPNSPENKNPCNIYYSPNDEDKGMVLPGTKCADRKACSNGQCVDVTTP

~~~~HHHHHHHHS~EEEEEEEEE~HHHHHHTTT~HHHHHHHHHHHHHHHHHHHHTTTEEEEEEEEEE~~SS~SS~~~S~HHHHHHHHHHHHHHTGGGT~~~SEEEEEESS~~SSS~~EEE~TT~TT~TTT~EEEEE~~BSSHHHHHHHHHHHHHHHTT~~~~~TT~~SSSS~~TT~SS~~SS~~S~~~HHHHHHHHHHHHHH~~SGGGS~~~GGG~~S~~~TTSSS~~TT~S~~~S~GGG~~~TTEETTTTEE~TT~S~SSSTTEETTEE~~TT~EEE~~SSTTB~~EE~~SS~S~~~~~BS~TT~EETTTTEE~BTTB~~~HHHHHHHHH~TT~EE~~GGGGGGGGG~~SS~~SB~SSSS~B~~~GGGTTSSB~~EE~~~TT~~~S~B~~~~SS~TTTTB~~TT~B~SSSEEESSSSEEES~~~~HHHHHHHHS~EEEEEEEEE~HHHHHHTTT~HHHHHHHHHHHHHHHHHHHHTTTEEEEEEEEEE~SS~~SS~~~S~HHHHHHHHHHHHHHTHHHH~~~SEEEEEE~S~~SSS~~EEE~TT~TT~TTT~EEEEE~~BSSHHHHHHHHHHHHHHHTT~~~~~TT~~SSSS~~TT~SS~~TT~~S~~~HHHHHHHHHHHHHH~~GGGG~~~~TTT~~S~~~TTSSS~~TT~S~~~SSTTT~~~TTEETTTTEE~TT~S~SSSTTEETTEE~~TT~B~S~~~SSSB~~~B~~SS~SS~~~~B~~TT~EETTTTEE~BTTB~~~HHHHHHHHH~TT~EE~~GGGGGGGGG~SSS~~SEESSS~EE~~~TT~GGGSB~~EE~~~S~~~~S~B~~~~SS~TTTTB~~TT~EEETTEEESSS~EEE~S~~

S N L T P E Q Q R Y L N A K K Y V K L F L V A D Y I M Y L K Y G R N L T A V R T R M Y D I V N V I T P I Y H R M N I H V A L V G L E I W S N T D K I I V Q S S A D V T L D L F A K W R A T D L L S R K S H D N A Q L L T G I N F N G P T A G L G Y L G G I C N T M Y S A G I V Q D H S K I H H L V A I A M A H E M G H N L G M D H D K D T C T C G T R P C V M A G A L S C E A S F L F S D C S Q K D H R E F L I K N M P Q C I L K K P L K T D V V S P A V C G N Y F V E V G E E C D C G S P R T C R D P C C D A T T C K L R Q G A Q C A E G L C C D Q C R F K G A G T E C R A A K D E C D M A D V C T G R S A E C T D R F Q R N G Q P C K N N N G Y C Y N G K C P I M A D Q C I A L F G P G A T V S Q D A C F Q F N R E G N H Y G Y C R K E Q N T K I A C E P Q D V K C G R L Y C F P N S P E N K N P C N I Y Y S P N D E D K G M V L P G T K C A D R K A C S N G Q C V D V T T L T P E Q Q R Y L N A K K Y V K L F L V A D Y I M Y L K Y G R N L T A V R T R M Y D I V N V I T P I Y H R M N I H V A L V G L E I W S N T D K I I V Q S S A D V T L D L F A K W R A T D L L S R K S H D N A Q L L T G I N F N G P T A G L G Y L G G I C N T M Y S A G I V Q D H S K I H H L V A I A M A H E M G H N L G M D H D K D T C T C G T R P C V M A G A L S C E A S F L F S D C S Q K D H R E F L I K N M P Q C I L K K P L K T D V V S P A V C G N Y F V E V G E E C D C G S P R T C R D P C C D A T T C K L R Q G A Q C A E G L C C D Q C R F K G A G T E C R A A K D E C D M A D V C T G R S A E C T D R F Q R N G Q P C K N N N G Y C Y N G K C P I M A D Q C I A L F G P G A T V S Q D A C F Q F N R E G N H Y G Y C R K E Q N T K I A C E P Q D V K C G R L Y C F P N S P E N K N P C N I Y Y S P N D E D K G M V L P G T K C A D R K A C S N G Q C V D V T T P

UNSTRUCTURED

AH

3QYW

PEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDLPKEKLKELIFEETARFQP

~~EETTEE~~~TTTEEEEEEEEE~SSSEEEEEEETTTTEEEEEEEE~~TT~HHHHHHHHHHHHHHHH~~~TTB~~~SEEE~~SSTTT~~~EEEEEE~~SEEHHHHHHH~~~~HHHHHHHHHHHHHHHHHHHHTTEE~~~~~GGGEEE~~~~EEE~~~TT~EE~~GGG~B~~TT~~~~S~GGG~~HHHHHTB~S~STHHHHHHHHHHHHHHHHSS~SS~~SSGGGHHHHHHHHH~S~~HHHHHT~~~HHHHHHHHTS~~~~~~~HHHH~TTS~HHHHHHHHHHT~SSTTTS~~HHHHHTSGGGTTT~~GGGS~~~SS~~~~~~~HHHHHHHHHHHHGGG~~

P E M V R G Q V F D V G P R Y T N L S Y I G E G A Y G M V C S A Y D N L N K V R V A I K K I S P F E H Q T Y C Q R T L R E I K I L L R F R H E N I I G I N D I I R A P T I E Q M K D V Y I V Q D L M E T D L Y K L L K T Q H L S N D H I C Y F L Y Q I L R G L K Y I H S A N V L H R D L K P S N L L L N T T D L K I C D F G L A R V A D P D H D H T G F L T E Y V A T R W Y R A P E I M L N S K G Y T K S I D I W S V G C I L A E M L S N R P I F P G K H Y L D Q L N H I L G I L G S P S Q E D L N C I I N L K A R N Y L L S L P H K N K V P W N R L F P N A D S K A L D L L D K M L T F N P H K R I E V E Q A L A H P Y L E Q Y Y D P S D E P I A E A P F K F D L P K E K L K E L I F E E T A R F Q P

AH

UNSTRUCTURED

2.00E+10

MLGLKTSIIGRRVIYFQEITSTNEFAKTSYLEEGTVIVADKQTMGESPEGGLWLSIVLSPKKIVFLGAVGVVETLKEFSIDGRIKWPNDVLVNYKKIAGVLVEGKIVLGIGLNVNNKVPNGATSMKLELGSEVPLLSVFRSLITNLDRLYLNFLKNPMDILNLVRDNMILGVRVKILGDGSFEGIAEDIDDFGRLIIRLDSGEVKKVIYGDVSLRFLMLGLKTSIIGRRVIYFQEITSTNEFAKTSYLEEGTVIVADKQTMSPEGGLWLSIVLSPKVPQKDLPKIVFLGAVGVVETLKEFSIDGRIKWPNDVLVNYKKIAGVLVEGKGDKIVLGIGLNVNNKVPNGATSMKLELGSEVPLLSVFRSLITNLDRLYLNFLKNPMDILNLVRDNMILGVRVKILGDGSFEGIAEDIDDFGRLIIRLDSGEVKKVIYSLRFL

~~~~~~SSTTSEEEEES~BS~HHHHHHHS~~~TT~EEEES~BS~~~B~TTSEEEEEEE~~~~HHHHHHHHHHHHHHHTT~~~EEETTTEEEETTEEEEEEEEE~~EEEEEEE~SSS~~~TT~~~HHHHHTS~~~HHHHHHHHHHHHHHHHHHHHH~TTHHHHHHHHTB~~SSEEEEESSSEEEEEEEEE~TTS~EEEE~TTS~EEEE~SSS~EEEE~~~~~~~SSTTSEEEEESSBS~HHHHHHHS~~~TT~EEEES~B~~~~TTSEEEEEEE~~~S~GGGGGGHHHHHHHHHHHHHHHTT~~~EEETTTEEEETTEEEEEEEEEEETTEEEEEEEE~SSS~~~TT~~~HHHHHTS~~~HHHHHHHHHHHHHHHHHHHHH~TTHHHHHHHHTB~~SEEEEE~STT~EEEEEEEE~TT~~EEEE~TTS~EEEE~~~EEE~

M L G L K T S I I G R R V I Y F Q E I T S T N E F A K T S Y L E E G T V I V A D K Q T M G E S P E G G L W L S I V L S P K K I V F L G A V G V V E T L K E F S I D G R I K W P N D V L V N Y K K I A G V L V E G K I V L G I G L N V N N K V P N G A T S M K L E L G S E V P L L S V F R S L I T N L D R L Y L N F L K N P M D I L N L V R D N M I L G V R V K I L G D G S F E G I A E D I D D F G R L I I R L D S G E V K K V I Y G D V S L R F L M L G L K T S I I G R R V I Y F Q E I T S T N E F A K T S Y L E E G T V I V A D K Q T M S P E G G L W L S I V L S P K V P Q K D L P K I V F L G A V G V V E T L K E F S I D G R I K W P N D V L V N Y K K I A G V L V E G K G D K I V L G I G L N V N N K V P N G A T S M K L E L G S E V P L L S V F R S L I T N L D R L Y L N F L K N P M D I L N L V R D N M I L G V R V K I L G D G S F E G I A E D I D D F G R L I I R L D S G E V K K V I Y S L R F L

BS

AH

4UEQ

AKHRPSVVWLHNAECTGCTEAAIRTIKPYIDALILDTISLDYQETIMAAAGEAAEAALHQALEGKDGYYLVVEGGLPTIDGGQWGMVAGHPMIETTKKAAAKAKGIICIGTCSAYGGVQKAKPNPSQAKGVSEALGVKTINIPGCPPNPINFVGAVVHVLTKGIPDLDENGRPKLFYGELVHDNCPRLPHFEASEFAPSFDSEEAKKGFCLYELGCKGPVTYNNCPKVLFNQVNWPVQAGHPCLGCSEPDFWDTMTPFYEQGAKHRPSVVWLHNAECTGCTEAAIRTIKPYIDALILDTISLDYQETIMAAAGEAAEAALHQALEGKDGYYLVVEGGLPTIDGGQWGMVAGHPMIETTKKAAAKAKGIICIGTCSAYGGVQKAKPNPSQAKGVSEALGVKTINIPGCPPNPINFVGAVVHVLTKGIPDLDENGRPKLFYGELVHDNCPRLPHFEASEFAPSFDSEEAKKGFCLYELGCKGPVTYNNCPKVLFNQVNWPVQAGHPCLGCSEPDFWDTMTPFYEQGKHRPSVVWLHNAECTGCTEAAIRTIKPYIDALILDTISLDYQETIMAAAGEAAEAALHQALEGKDGYYLVVEGGLPTIDGGQWGMVAGHPMIETTKKAAAKAKGIICIGTCSAYGGVQKAKPNPSQAKGVSEALGVKTINIPGCPPNPINFVGAVVHVLTKGIPDLDENGRPKLFYGELVHDNCPRLPHFEASEFAPSFDSEEAKKGFCLYELGCKGPVTYNNCPKVLFNQVNWPVQAGHPCLGCSEPDFWDTMTPFYEQGAKHRPSVVWLHNAECTGCTEAAIRTIKPYIDALILDTISLDYQETIMAAAGEAAEAALHQALEGKDGYYLVVEGGLPTIDGGQWGMVAGHPMIETTKKAAAKAKGIICIGTCSAYGGVQKAKPNPSQAKGVSEALGVKTINIPGCPPNPINFVGAVVHVLTKGIPDLDENGRPKLFYGELVHDNCPRLPHFEASEFAPSFDSEEAKKGFCLYELGCKGPVTYNNCPKVLFNQVNWPVQAGHPCLGCSEPDFWDTMTPFYEQGAKHRPSVVWLHNAECTGCTEAAIRTIKPYIDALILDTISLDYQETIMAAAGEAAEAALHQALEGKDGYYLVVEGGLPTIDGGQWGMVAGHPMIETTKKAAAKAKGIICIGTCSAYGGVQKAKPNPSQAKGVSEALGVKTINIPGCPPNPINFVGAVVHVLTKGIPDLDENGRPKLFYGELVHDNCPRLPHFEASEFAPSFDSEEAKKGFCLYELGCKGPVTYNNCPKVLFNQVNWPVQAGHPCLGCSEPDFWDTMTPFYEQGKHRPSVVWLHNAECTGCTEAAIRTIKPYIDALILDTISLDYQETIMAAAGEAAEAALHQALEGKDGYYLVVEGGLPTIDGGQWGMVAGHPMIETTKKAAAKAKGIICIGTCSAYGGVQKAKPNPSQAKGVSEALGVKTINIPGCPPNPINFVGAVVHVLTKGIPDLDENGRPKLFYGELVHDNCPRLPHFEASEFAPSFDSEEAKKGFCLYELGCKGPVTYNNCPKVLFNQVNWPVQAGHPCLGCSEPDFWDTMTPFYEQGPTPQSTFTGPIVVDPITRIEGHLRIMVEVENGKVKDAWSSSQLFRGLEIILKGRDPRDAQHFTQRACGCCTYVHALASSRCVDDAVKVSIPANARMMRNLVMASQYLHDHLVHFYHLHALDWVDVTAALKADPNKAAKLAASIAPARPGNSAKALKAVQDKLKAFVESGQLGIFTNAYFLGGHKAYYLPPEVDLIATAHYLEALHMQVKAASAMAILGGKNPHTQFTVVGGCSNYQGLTKDPLANYLALSKEVCQFVNECYIPDLLAVAGFYKDWGGIGGTSNYLAFGEFATDDSSPEKHLATSQFPSGVITGRDLGKVDNVDLGAIYEDVKYSWYAPGGDGKHPYDGVTDPKYTKLDDKDHYSWMKAPRYKGKAMEVGPLARTFIAYAKGQPDFKKVVDMVLGKLSVPATALHSTLGRTAARGIETAIVCANMEKWIKEMADSGAKDNTLCAKWEMPEESKGVGLADAPRGALSHWIRIKGKKIDNFQLVVPSTWNLGPRGAQGDKSPVEEALIGTPIADPKRPVEILRTVHAFDPCIACGVHKPTPQSTFTGPIVVDPITRIEGHLRIMVEVENGKVKDAWSSSQLFRGLEIILKGRDPRDAQHFTQRACGCCTYVHALASSRCVDDAVKVSIPANARMMRNLVMASQYLHDHLVHFYHLHALDWVDVTAALKADPNKAAKLAASIAPARPGNSAKALKAVQDKLKAFVESGQLGIFTNAYFLGGHKAYYLPPEVDLIATAHYLEALHMQVKAASAMAILGGKNPHTQFTVVGGCSNYQGLTKDPLANYLALSKEVCQFVNECYIPDLLAVAGFYKDWGGIGGTSNYLAFGEFATDDSSPEKHLATSQFPSGVITGRDLGKVDNVDLGAIYEDVKYSWYAPGGDGKHPYDGVTDPKYTKLDDKDHYSWMKAPRYKGKAMEVGPLARTFIAYAKGQPDFKKVVDMVLGKLSVPATALHSTLGRTAARGIETAIVCANMEKWIKEMADSGAKDNTLCAKWEMPEESKGVGLADAPRGALSHWIRIKGKKIDNFQLVVPSTWNLGPRGAQGDKSPVEEALIGTPIADPKRPVEILRTVHAFDPCIACGVHPTPQSTFTGPIVVDPITRIEGHLRIMVEVENGKVKDAWSSSQLFRGLEIILKGRDPRDAQHFTQRACGCCTYVHALASSRCVDDAVKVSIPANARMMRNLVMASQYLHDHLVHFYHLHALDWVDVTAALKADPNKAAKLAASIAPARPGNSAKALKAVQDKLKAFVESGQLGIFTNAYFLGGHKAYYLPPEVDLIATAHYLEALHMQVKAASAMAILGGKNPHTQFTVVGGCSNYQGLTKDPLANYLALSKEVCQFVNECYIPDLLAVAGFYKDWGGIGGTSNYLAFGEFATDDSSPEKHLATSQFPSGVITGRDLGKVDNVDLGAIYEDVKYSWYAPGGDGKHPYDGVTDPKYTKLDDKDHYSWMKAPRYKGKAMEVGPLARTFIAYAKGQPDFKKVVDMVLGKLSVPATALHSTLGRTAARGIETAIVCANMEKWIKEMADSGAKDNTLCAKWEMPEESKGVGLADAPRGALSHWIRIKGKKIDNFQLVVPSTWNLGPRGAQGDKSPVEEALIGTPIADPKRPVEILRTVHAFDPCIACGVHPTPQSTFTGPIVVDPITRIEGHLRIMVEVENGKVKDAWSSSQLFRGLEIILKGRDPRDAQHFTQRACGCCTYVHALASSRCVDDAVKVSIPANARMMRNLVMASQYLHDHLVHFYHLHALDWVDVTAALKADPNKAAKLAASIAPARPGNSAKALKAVQDKLKAFVESGQLGIFTNAYFLGGHKAYYLPPEVDLIATAHYLEALHMQVKAASAMAILGGKNPHTQFTVVGGCSNYQGLTKDPLANYLALSKEVCQFVNECYIPDLLAVAGFYKDWGGIGGTSNYLAFGEFATDDSSPEKHLATSQFPSGVITGRDLGKVDNVDLGAIYEDVKYSWYAPGGDGKHPYDGVTDPKYTKLDDKDHYSWMKAPRYKGKAMEVGPLARTFIAYAKGQPDFKKVVDMVLGKLSVPATALHSTLGRTAARGIETAIVCANMEKWIKEMADSGAKDNTLCAKWEMPEESKGVGLADAPRGALSHWIRIKGKKIDNFQLVVPSTWNLGPRGAQGDKSPVEEALIGTPIADPKRPVEILRTVHAFDPCIACGVHKPTPQSTFTGPIVVDPITRIEGHLRIMVEVENGKVKDAWSSSQLFRGLEIILKGRDPRDAQHFTQRACGCCTYVHALASSRCVDDAVKVSIPANARMMRNLVMASQYLHDHLVHFYHLHALDWVDVTAALKADPNKAAKLAASIAPARPGNSAKALKAVQDKLKAFVESGQLGIFTNAYFLGGHKAYYLPPEVDLIATAHYLEALHMQVKAASAMAILGGKNPHTQFTVVGGCSNYQGLTKDPLANYLALSKEVCQFVNECYIPDLLAVAGFYKDWGGIGGTSNYLAFGEFATDDSSPEKHLATSQFPSGVITGRDLGKVDNVDLGAIYEDVKYSWYAPGGDGKHPYDGVTDPKYTKLDDKDHYSWMKAPRYKGKAMEVGPLARTFIAYAKGQPDFKKVVDMVLGKLSVPATALHSTLGRTAARGIETAIVCANMEKWIKEMADSGAKDNTLCAKWEMPEESKGVGLADAPRGALSHWIRIKGKKIDNFQLVVPSTWNLGPRGAQGDKSPVEEALIGTPIADPKRPVEILRTVHAFDPCIACGVHPTPQSTFTGPIVVDPITRIEGHLRIMVEVENGKVKDAWSSSQLFRGLEIILKGRDPRDAQHFTQRACGCCTYVHALASSRCVDDAVKVSIPANARMMRNLVMASQYLHDHLVHFYHLHALDWVDVTAALKADPNKAAKLAASIAPARPGNSAKALKAVQDKLKAFVESGQLGIFTNAYFLGGHKAYYLPPEVDLIATAHYLEALHMQVKAASAMAILGGKNPHTQFTVVGGCSNYQGLTKDPLANYLALSKEVCQFVNECYIPDLLAVAGFYKDWGGIGGTSNYLAFGEFATDDSSPEKHLATSQFPSGVITGRDLGKVDNVDLGAIYEDVKYSWYAPGGDGKHPYDGVTDPKYTKLDDKDHYSWMKAPRYKGKAMEVGPLARTFIAYAKGQPDFKKVVDMVLGKLSVPATALHSTLGRTAARGIETAIVCANMEKWIKEMADSGAKDNTLCAKWEMPEESKGVGLADAPRGALSHWIRIKGKKIDNFQLVVPSTWNLGPRGAQGDKSPVEEALIGTPIADPKRPVEILRTVHAFDPCIACGVH

~~~~~EEEEEE~B~~SHHHHHHTT~BTTBHHHHHHHT~EEEE~TTT~S~~HHHHHHHHHHHHT~TT~EEEEEESBEE~GGGGTTBEETTEEHHHHHHHHHHT~S~EEEESHHHHH~~GGGSTT~TT~EE~HHHHHTS~~EEE~SSS~~HHHHHHHHHHHHHT~~~~B~TTS~BHHHHSSBTGGG~TTHHHHHTT~B~SSTTSHHHHTT~B~GGGT~~GGG~B~~HHHH~BTTTB~TTTTT~~~~~TTSTTHHHHS~STT~~~~~~~~EEEEEE~B~~SHHHHHHTT~BTTBHHHHHHHT~EEEE~TTT~S~~HHHHHHHHHHHHT~TT~~EEEEESBEE~GGGGTTBEETTEEHHHHHHHHHHH~S~EEEEHHHHHH~~GGGSTT~TT~EE~HHHHH~~~~EEE~SSS~~HHHHHHHHHHHHHT~S~~B~TTS~BHHHHSSBTGGG~TTHHHHHTT~B~SSTTSHHHHTT~B~GGGT~~GGG~B~~HHHH~BTTTB~TTTTT~~~~~TTSTTHHHHS~STTS~~~~~~EEEEEE~B~~SHHHHHHTT~BTTBHHHHHHHT~EEEE~TTT~S~~HHHHHHHHHHHHT~TT~~EEEEESBEE~TGGGTTBEETTEEHHHHHHHHHHH~S~EEEESHHHHH~~GGGSTT~TT~EE~HHHHHT~~~EEE~SSS~~HHHHHHHHHHHHHT~S~~B~TTS~BHHHHSSBTGGG~TTHHHHHTT~B~SSTTSHHHHTT~B~GGGT~~GGG~B~~HHHH~BTTTB~TTTTT~~~~~TTSTTHHHHS~STTS~~~~~~~EEEEEE~B~~SHHHHHHTT~BTTBHHHHHHHT~EEEE~TTT~S~~HHHHHHHHHHHHT~TT~EEEEEESBEE~GGGGTTBEETTEEHHHHHHHHHHH~S~EEEESHHHHH~~GGGSTT~TT~EE~HHHHHTS~~EEE~SSS~~HHHHHHHHHHHHHT~S~~B~TTS~BHHHHSSBTGGG~TTHHHHHTT~B~SSTTSHHHHTT~B~GGGT~~GGG~B~~HHHH~BTTTB~TTTTT~~~~~TTSTTHHHHS~STT~~~~~~~~EEEEEE~B~~SHHHHHHTT~BTTBHHHHHHHT~EEEE~TTT~S~~HHHHHHHHHHHHT~TT~EEEEEESBEE~GGGGTTBEETTEEHHHHHHHHHHH~S~EEEEHHHHHH~~GGGSTT~TT~EE~HHHHH~~~~EEE~SSS~~HHHHHHHHHHHHHT~S~~B~TTS~BHHHHSSBTGGG~TTHHHHHTT~B~SSTTSHHHHTT~B~GGGT~~GGG~B~~HHHH~BTTTB~TTTTT~~~~~TTSTTHHHHS~STTS~~~~~~EEEEEE~B~~SHHHHHHTT~BTTBHHHHHHHT~EEEE~TTT~S~~HHHHHHHHHHHHH~TT~~EEEEESBEE~GGGGTTBEETTEEHHHHHHHHHHH~S~EEEESHHHHH~~GGGSTT~TT~EE~HHHHH~~~~EEE~SSS~~HHHHHHHHHHHHHT~S~~B~TTS~BHHHHSSBTGGG~TTHHHHHTT~B~SSTTSHHHHTT~B~GGGT~~GGG~B~~HHHH~BTTTB~TTTTT~~~~~TTSTTHHHHS~STT~~~~~~~~~~~EEEEE~S~~SSBS~EEEEEEEETTEEEEEEEEE~B~~~HHHHHTTS~GGGHHHHHHTT~STTTTHHHHHHHHHHHHHHT~~~~HHHHHHHHHHHHHHHHHHHHHHHHHTTGGGT~~GGGGGG~~HHHHHHHHHHHS~~~GGGSHHHHHHHHHHHHHHHHTT~~GGGTT~TTTT~~TT~~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSS~~~EETTEE~~GGGGSHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHH~GGGGGSS~~S~EEE~~EEES~~SSHHHHHHHEEE~~EEE~TT~TT~~B~~~GGGEEEE~TTSSB~TT~TTB~GGG~~~~B~~~~TT~TTS~~SS~EEEETTB~~B~SHHHHHHHHHHTT~HHHHHHHHHHHHHHT~~GGGGSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~~~~B~~~~~~SSEEEEEEEEETTEEEEEEEEEETTEEEEEEEE~HHHHHH~~~~TT~~~~HHHHHHTT~B~S~TTS~HHHHHHHHHT~~BHHHHH~~~~~~~~~~EEEEE~S~~SSBS~EEEEEEEETTEEEEEEEEE~B~~~HHHHHTTS~GGGHHHHHGGG~STTTTHHHHHHHHHHHHHTT~~~~HHHHHHHHHHHHHHHHHHHHHHHHHTTGGGT~~TGGGGGS~HHHHHHHHHHHS~~~GGGSHHHHHHHHHHHHHHHHTT~~GGGTT~TTTT~~TT~~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSS~~~EETTEE~~GGGGSHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHTGGGGGSS~~~~EEE~~EEES~~SSHHHHHHHEEE~~EEE~TT~TT~~B~~~GGGEEEE~TTBSB~TT~TTB~GGG~~~~B~~~~TT~TTS~BSS~EEEETTB~~B~SHHHHHHHHHHTT~HHHHHHHHHHHHHHT~~GGGGSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~~~~B~~~~~~SEEEEEEEEEETTEEEEEEEEEETTEEEEEEEE~HHHHHH~~~~TT~~~~HHHHHHTT~B~S~TTS~HHHHHHHHHT~~BHHHHH~~~~~~~~~EEEEE~S~~SSBS~EEEEEEEETTEEEEEEEEE~B~~~HHHHHTTS~GGGHHHHHHTT~STTTTHHHHHHHHHHHHHHT~~~~HHHHHHHHHHHHHHHHHHHHHHHHHTTGGGT~~GGGGGGS~HHHHHHHHHHHS~~~GGGSHHHHHHHHHHHHHHHHTS~~GGGTT~TTTT~~TT~~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSS~~~EETTEE~~GGGGSHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHTGGGGGSS~~S~EEE~~EEES~~SSHHHHHHHEEE~~EEE~TT~TT~~B~~~GGGEEEE~TTBTB~SS~TTB~GGG~~~~B~~~~TTBTTB~BSS~EEEETTB~~B~SHHHHHHHHHHTT~HHHHHHHHHHHHHHT~~GGGGSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~~~~B~~~~~~SSEEEEEEEEETTEEEEEEEEEETTEEEEEEEE~HHHHHH~~~~TT~~~~HHHHHHTT~B~S~TTS~HHHHHHHHHT~~BHHHHH~~~~~~~~~EEEEE~S~~SSBS~EEEEEEEETTEEEEEEEEE~B~~~HHHHHTTS~GGGHHHHHHTT~STTTTHHHHHHHHHHHHHHT~~~~HHHHHHHHHHHHHHHHHHHHHHHHHTTGGGT~~TGGGGGS~HHHHHHHHHHHS~~~GGGSHHHHHHHHHHHHHHHHTT~~GGGTT~TTTT~~TT~~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSS~~~EETTEE~~GGGGSHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHTGGGGGSS~~S~EEE~~EEES~~SSHHHHHHHEEE~~EEE~TT~TT~~B~~~GGGEEEE~TTSSB~TT~TTB~GGG~~~~B~~~~TT~TTS~~SS~EEEETTB~~B~SHHHHHHHHHHTT~HHHHHHHHHHHHHHT~~GGGGSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~~~~B~~~~~~SSEEEEEEEEETTEEEEEEEEEETTEEEEEEEE~HHHHHH~~~~TT~~~~HHHHHHTT~B~S~TTS~HHHHHHHHHT~~BHHHHH~~~~~~~~~~EEEEE~S~~SSBS~EEEEEEEETTEEEEEEEEE~B~~~HHHHHTTS~GGGHHHHHGGG~SSSTTHHHHHHHHHHHHHHT~~~~HHHHHHHHHHHHHHHHHHHHHHHHHTTGGGT~~TGGGGGS~HHHHHHHHHHHS~~~GGGSHHHHHHHHHHHHHHHHTS~~GGGTT~TTTT~~TT~~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSS~~~EETTEE~~GGGGSHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHH~GGGGGSS~~S~EEE~~EEES~~SSHHHHHHHEEE~~EEE~TT~TT~~B~~~GGGEEEE~TTBSB~TT~TTB~GGG~~~~B~~~~TT~TTS~BSS~EEEETTB~~B~SHHHHHHHHHHTT~HHHHHHHHHHHHHHT~~GGGGSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~~~~B~~~~~~SSEEEEEEEEETTEEEEEEEEEETTEEEEEEEE~HHHHHH~~~~TT~~~~HHHHHHTT~B~S~TTS~HHHHHHHHHT~~BHHHHH~~~~~~~~~EEEEE~S~~SSBS~EEEEEEEETTEEEEEEEEE~B~~~HHHHHTTS~GGGHHHHHHTT~STTTTHHHHHHHHHHHHHHT~~~~HHHHHHHHHHHHHHHHHHHHHHHHHTTGGGT~~TGGGGGS~HHHHHHHHHHHS~~~GGGSHHHHHHHHHHHHHHHTTS~~GGGTT~TTTT~~TT~~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSS~~~EETTEE~~GGGGSHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHTGGGGGSS~~S~EEE~~EEES~~SSHHHHHHHEEE~~EEE~TT~TT~~B~~~GGGEEEE~TTTTB~SS~TTB~GGG~~~~B~~~~TTBTTB~~SS~EEEETTB~~B~SHHHHHHHHHHTT~HHHHHHHHHHHHHHT~~GGGGSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~~~~B~~~~~~SSEEEEEEEEETTEEEEEEEEEETTEEEEEEEE~HHHHHH~~~~TT~~~~HHHHHHTT~B~S~TTS~HHHHHHHHHT~~BHHHHH~

A K H R P S V V W L H N A E C T G C T E A A I R T I K P Y I D A L I L D T I S L D Y Q E T I M A A A G E A A E A A L H Q A L E G K D G Y Y L V V E G G L P T I D G G Q W G M V A G H P M I E T T K K A A A K A K G I I C I G T C S A Y G G V Q K A K P N P S Q A K G V S E A L G V K T I N I P G C P P N P I N F V G A V V H V L T K G I P D L D E N G R P K L F Y G E L V H D N C P R L P H F E A S E F A P S F D S E E A K K G F C L Y E L G C K G P V T Y N N C P K V L F N Q V N W P V Q A G H P C L G C S E P D F W D T M T P F Y E Q G A K H R P S V V W L H N A E C T G C T E A A I R T I K P Y I D A L I L D T I S L D Y Q E T I M A A A G E A A E A A L H Q A L E G K D G Y Y L V V E G G L P T I D G G Q W G M V A G H P M I E T T K K A A A K A K G I I C I G T C S A Y G G V Q K A K P N P S Q A K G V S E A L G V K T I N I P G C P P N P I N F V G A V V H V L T K G I P D L D E N G R P K L F Y G E L V H D N C P R L P H F E A S E F A P S F D S E E A K K G F C L Y E L G C K G P V T Y N N C P K V L F N Q V N W P V Q A G H P C L G C S E P D F W D T M T P F Y E Q G K H R P S V V W L H N A E C T G C T E A A I R T I K P Y I D A L I L D T I S L D Y Q E T I M A A A G E A A E A A L H Q A L E G K D G Y Y L V V E G G L P T I D G G Q W G M V A G H P M I E T T K K A A A K A K G I I C I G T C S A Y G G V Q K A K P N P S Q A K G V S E A L G V K T I N I P G C P P N P I N F V G A V V H V L T K G I P D L D E N G R P K L F Y G E L V H D N C P R L P H F E A S E F A P S F D S E E A K K G F C L Y E L G C K G P V T Y N N C P K V L F N Q V N W P V Q A G H P C L G C S E P D F W D T M T P F Y E Q G A K H R P S V V W L H N A E C T G C T E A A I R T I K P Y I D A L I L D T I S L D Y Q E T I M A A A G E A A E A A L H Q A L E G K D G Y Y L V V E G G L P T I D G G Q W G M V A G H P M I E T T K K A A A K A K G I I C I G T C S A Y G G V Q K A K P N P S Q A K G V S E A L G V K T I N I P G C P P N P I N F V G A V V H V L T K G I P D L D E N G R P K L F Y G E L V H D N C P R L P H F E A S E F A P S F D S E E A K K G F C L Y E L G C K G P V T Y N N C P K V L F N Q V N W P V Q A G H P C L G C S E P D F W D T M T P F Y E Q G A K H R P S V V W L H N A E C T G C T E A A I R T I K P Y I D A L I L D T I S L D Y Q E T I M A A A G E A A E A A L H Q A L E G K D G Y Y L V V E G G L P T I D G G Q W G M V A G H P M I E T T K K A A A K A K G I I C I G T C S A Y G G V Q K A K P N P S Q A K G V S E A L G V K T I N I P G C P P N P I N F V G A V V H V L T K G I P D L D E N G R P K L F Y G E L V H D N C P R L P H F E A S E F A P S F D S E E A K K G F C L Y E L G C K G P V T Y N N C P K V L F N Q V N W P V Q A G H P C L G C S E P D F W D T M T P F Y E Q G K H R P S V V W L H N A E C T G C T E A A I R T I K P Y I D A L I L D T I S L D Y Q E T I M A A A G E A A E A A L H Q A L E G K D G Y Y L V V E G G L P T I D G G Q W G M V A G H P M I E T T K K A A A K A K G I I C I G T C S A Y G G V Q K A K P N P S Q A K G V S E A L G V K T I N I P G C P P N P I N F V G A V V H V L T K G I P D L D E N G R P K L F Y G E L V H D N C P R L P H F E A S E F A P S F D S E E A K K G F C L Y E L G C K G P V T Y N N C P K V L F N Q V N W P V Q A G H P C L G C S E P D F W D T M T P F Y E Q G P T P Q S T F T G P I V V D P I T R I E G H L R I M V E V E N G K V K D A W S S S Q L F R G L E I I L K G R D P R D A Q H F T Q R A C G C C T Y V H A L A S S R C V D D A V K V S I P A N A R M M R N L V M A S Q Y L H D H L V H F Y H L H A L D W V D V T A A L K A D P N K A A K L A A S I A P A R P G N S A K A L K A V Q D K L K A F V E S G Q L G I F T N A Y F L G G H K A Y Y L P P E V D L I A T A H Y L E A L H M Q V K A A S A M A I L G G K N P H T Q F T V V G G C S N Y Q G L T K D P L A N Y L A L S K E V C Q F V N E C Y I P D L L A V A G F Y K D W G G I G G T S N Y L A F G E F A T D D S S P E K H L A T S Q F P S G V I T G R D L G K V D N V D L G A I Y E D V K Y S W Y A P G G D G K H P Y D G V T D P K Y T K L D D K D H Y S W M K A P R Y K G K A M E V G P L A R T F I A Y A K G Q P D F K K V V D M V L G K L S V P A T A L H S T L G R T A A R G I E T A I V C A N M E K W I K E M A D S G A K D N T L C A K W E M P E E S K G V G L A D A P R G A L S H W I R I K G K K I D N F Q L V V P S T W N L G P R G A Q G D K S P V E E A L I G T P I A D P K R P V E I L R T V H A F D P C I A C G V H K P T P Q S T F T G P I V V D P I T R I E G H L R I M V E V E N G K V K D A W S S S Q L F R G L E I I L K G R D P R D A Q H F T Q R A C G C C T Y V H A L A S S R C V D D A V K V S I P A N A R M M R N L V M A S Q Y L H D H L V H F Y H L H A L D W V D V T A A L K A D P N K A A K L A A S I A P A R P G N S A K A L K A V Q D K L K A F V E S G Q L G I F T N A Y F L G G H K A Y Y L P P E V D L I A T A H Y L E A L H M Q V K A A S A M A I L G G K N P H T Q F T V V G G C S N Y Q G L T K D P L A N Y L A L S K E V C Q F V N E C Y I P D L L A V A G F Y K D W G G I G G T S N Y L A F G E F A T D D S S P E K H L A T S Q F P S G V I T G R D L G K V D N V D L G A I Y E D V K Y S W Y A P G G D G K H P Y D G V T D P K Y T K L D D K D H Y S W M K A P R Y K G K A M E V G P L A R T F I A Y A K G Q P D F K K V V D M V L G K L S V P A T A L H S T L G R T A A R G I E T A I V C A N M E K W I K E M A D S G A K D N T L C A K W E M P E E S K G V G L A D A P R G A L S H W I R I K G K K I D N F Q L V V P S T W N L G P R G A Q G D K S P V E E A L I G T P I A D P K R P V E I L R T V H A F D P C I A C G V H P T P Q S T F T G P I V V D P I T R I E G H L R I M V E V E N G K V K D A W S S S Q L F R G L E I I L K G R D P R D A Q H F T Q R A C G C C T Y V H A L A S S R C V D D A V K V S I P A N A R M M R N L V M A S Q Y L H D H L V H F Y H L H A L D W V D V T A A L K A D P N K A A K L A A S I A P A R P G N S A K A L K A V Q D K L K A F V E S G Q L G I F T N A Y F L G G H K A Y Y L P P E V D L I A T A H Y L E A L H M Q V K A A S A M A I L G G K N P H T Q F T V V G G C S N Y Q G L T K D P L A N Y L A L S K E V C Q F V N E C Y I P D L L A V A G F Y K D W G G I G G T S N Y L A F G E F A T D D S S P E K H L A T S Q F P S G V I T G R D L G K V D N V D L G A I Y E D V K Y S W Y A P G G D G K H P Y D G V T D P K Y T K L D D K D H Y S W M K A P R Y K G K A M E V G P L A R T F I A Y A K G Q P D F K K V V D M V L G K L S V P A T A L H S T L G R T A A R G I E T A I V C A N M E K W I K E M A D S G A K D N T L C A K W E M P E E S K G V G L A D A P R G A L S H W I R I K G K K I D N F Q L V V P S T W N L G P R G A Q G D K S P V E E A L I G T P I A D P K R P V E I L R T V H A F D P C I A C G V H P T P Q S T F T G P I V V D P I T R I E G H L R I M V E V E N G K V K D A W S S S Q L F R G L E I I L K G R D P R D A Q H F T Q R A C G C C T Y V H A L A S S R C V D D A V K V S I P A N A R M M R N L V M A S Q Y L H D H L V H F Y H L H A L D W V D V T A A L K A D P N K A A K L A A S I A P A R P G N S A K A L K A V Q D K L K A F V E S G Q L G I F T N A Y F L G G H K A Y Y L P P E V D L I A T A H Y L E A L H M Q V K A A S A M A I L G G K N P H T Q F T V V G G C S N Y Q G L T K D P L A N Y L A L S K E V C Q F V N E C Y I P D L L A V A G F Y K D W G G I G G T S N Y L A F G E F A T D D S S P E K H L A T S Q F P S G V I T G R D L G K V D N V D L G A I Y E D V K Y S W Y A P G G D G K H P Y D G V T D P K Y T K L D D K D H Y S W M K A P R Y K G K A M E V G P L A R T F I A Y A K G Q P D F K K V V D M V L G K L S V P A T A L H S T L G R T A A R G I E T A I V C A N M E K W I K E M A D S G A K D N T L C A K W E M P E E S K G V G L A D A P R G A L S H W I R I K G K K I D N F Q L V V P S T W N L G P R G A Q G D K S P V E E A L I G T P I A D P K R P V E I L R T V H A F D P C I A C G V H K P T P Q S T F T G P I V V D P I T R I E G H L R I M V E V E N G K V K D A W S S S Q L F R G L E I I L K G R D P R D A Q H F T Q R A C G C C T Y V H A L A S S R C V D D A V K V S I P A N A R M M R N L V M A S Q Y L H D H L V H F Y H L H A L D W V D V T A A L K A D P N K A A K L A A S I A P A R P G N S A K A L K A V Q D K L K A F V E S G Q L G I F T N A Y F L G G H K A Y Y L P P E V D L I A T A H Y L E A L H M Q V K A A S A M A I L G G K N P H T Q F T V V G G C S N Y Q G L T K D P L A N Y L A L S K E V C Q F V N E C Y I P D L L A V A G F Y K D W G G I G G T S N Y L A F G E F A T D D S S P E K H L A T S Q F P S G V I T G R D L G K V D N V D L G A I Y E D V K Y S W Y A P G G D G K H P Y D G V T D P K Y T K L D D K D H Y S W M K A P R Y K G K A M E V G P L A R T F I A Y A K G Q P D F K K V V D M V L G K L S V P A T A L H S T L G R T A A R G I E T A I V C A N M E K W I K E M A D S G A K D N T L C A K W E M P E E S K G V G L A D A P R G A L S H W I R I K G K K I D N F Q L V V P S T W N L G P R G A Q G D K S P V E E A L I G T P I A D P K R P V E I L R T V H A F D P C I A C G V H P T P Q S T F T G P I V V D P I T R I E G H L R I M V E V E N G K V K D A W S S S Q L F R G L E I I L K G R D P R D A Q H F T Q R A C G C C T Y V H A L A S S R C V D D A V K V S I P A N A R M M R N L V M A S Q Y L H D H L V H F Y H L H A L D W V D V T A A L K A D P N K A A K L A A S I A P A R P G N S A K A L K A V Q D K L K A F V E S G Q L G I F T N A Y F L G G H K A Y Y L P P E V D L I A T A H Y L E A L H M Q V K A A S A M A I L G G K N P H T Q F T V V G G C S N Y Q G L T K D P L A N Y L A L S K E V C Q F V N E C Y I P D L L A V A G F Y K D W G G I G G T S N Y L A F G E F A T D D S S P E K H L A T S Q F P S G V I T G R D L G K V D N V D L G A I Y E D V K Y S W Y A P G G D G K H P Y D G V T D P K Y T K L D D K D H Y S W M K A P R Y K G K A M E V G P L A R T F I A Y A K G Q P D F K K V V D M V L G K L S V P A T A L H S T L G R T A A R G I E T A I V C A N M E K W I K E M A D S G A K D N T L C A K W E M P E E S K G V G L A D A P R G A L S H W I R I K G K K I D N F Q L V V P S T W N L G P R G A Q G D K S P V E E A L I G T P I A D P K R P V E I L R T V H A F D P C I A C G V H

AH

UNSTRUCTURED

5X1A

SDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRGVPRGLYDGPVCEV

~~~EEEEEEEEE~SS~EEEEEEEEETTEEEEEESS~~~~TT~EEEE~TT~EEEE~EEEEEE~TT~EETTEE~SS~HHHHHHHHHHTTEEEEEEEE~~~TTS~HHHHHHHHHHHHHHH~SSEEEEEEE~~~~~TTHHHHHHHHHHHS~~~EEEEESSSTTTTB~~HHHHHHHHHHHHHHT~EEEEE~S~HHHHHHHHHHHHHTT~~STHHHHHTS~HHHHHHHHHHHHHHHHHHT~~EEEEEE~~HHHHHHHHHHHHHT~~EEEEEBHHHHH~~GGGGG~SSHHHHHTT~~SS~~~S~TTHHHHHHHHHHHTSS~~~B~~B~~~~HHHHGGGTT~GGGS~~~B~~TTTHHHHHHHHHTTTTSS~HHHHHHHHTHHHHHHTT~TTTSS~~~TTSB~~EEEEEEEEEEE~~TTTSSSS~S~~TTTT~EEEEEEEEEEETTEEEEETTEE~~~TT~~~B~~~~SS~HHHHHHHHHHHTS~~~~~~~~~~~~S~~~~~

S D R L L I K G G K I V N D D Q S F Y A D I Y M E D G L I K Q I G E N L I V P G G V K T I E A H S R M V I P G G I D V H T R F Q M P D Q G M T S A D D F F Q G T K A A L A G G T T M I I D H V V P E P G T S L L A A F D Q W R E W A D S K S C C D Y S L H V D I S E W H K G I Q E E M E A L V K D H G V N S F L V Y M A F K D R F Q L T D C Q I Y E V L S V I R D I G A I A Q V H A E N G D I I A E E Q Q R I L D L G I T G P E G H V L S R P E E V E A E A V N R A I T I A N Q T N C P L Y I T K V M S K S S A E V I A Q A R K K G T V V Y G E P I T A S L G T D G S H Y W S K N W A K A A A F V T S P P L S P D P T T P D F L N S L L S C G D L Q V T G S A H C T F N T A Q K A V G K D N F T L I P E G T N G T E E R M S V I W D K A V V T G K M D E N Q F V A V T S T N A A K V F N L Y P R K G R I A V G S D A D L V I W D P D S V K T I S A K T H N S S L E Y N I F E G M E C R G S P L V V I S Q G K I V L E D G T L H V T E G S G R Y I P R K P F P D F V Y K R I K A R S R L A E L R G V P R G L Y D G P V C E V

AH

UNSTRUCTURED

4B7Q

VKLAGNSSLCPVSGWAIYSKDNSVRIGSKGDVFVIREPFISCSPLECRTFFLTQGALLNDKHSNGTIKDRSPYRTLMSCPIGEVPSPYNSRFESVAWSASACHDGINWLTIGISGPDNGAVAVLKYNGIITDTIKSWRNNILRTQESECACVNGSCFTVMTDGPSNGQASYKIFRIEKGKIVKSVEMNAPNYHYEECSCYPDSSEITCVCRDNWHGSNRPWVSFNQNLEYQIGYICSGIFGDNPRPNDKTGSCGPVSSNGANGVKGFSFKYGNGVWIGRTKSISSRNGFEMIWDPNGWTGTDNNFSIKQDIVGINEWSGYSGSFVQHPELTGLDCIRPCFWVELIRGRPKENTIWTSGSSISFCGVNSDTVGWSWPDGAELPFTIDKVKLAGNSSLCPVSGWAIYSKDNSVRIGSKGDVFVIREPFISCSPLECRTFFLTQGALLNDKHSNGTIKDRSPYRTLMSCPIGEVPSPYNSRFESVAWSASACHDGINWLTIGISGPDNGAVAVLKYNGIITDTIKSWRNNILRTQESECACVNGSCFTVMTDGPSNGQASYKIFRIEKGKIVKSVEMNAPNYHYEECSCYPDSSEITCVCRDNWHGSNRPWVSFNQNLEYQIGYICSGIFGDNPRPNDKTGSCGPVSSNGANGVKGFSFKYGNGVWIGRTKSISSRNGFEMIWDPNGWTGTDNNFSIKQDIVGINEWSGYSGSFVQHPELTGLDCIRPCFWVELIRGRPKENTIWTSGSSISFCGVNSDTVGWSWPDGAELPFTIDKVKLAGNSSLCPVSGWAIYSKDNSVRIGSKGDVFVIREPFISCSPLECRTFFLTQGALLNDKHSNGTIKDRSPYRTLMSCPIGEVPSPYNSRFESVAWSASACHDGINWLTIGISGPDNGAVAVLKYNGIITDTIKSWRNNILRTQESECACVNGSCFTVMTDGPSNGQASYKIFRIEKGKIVKSVEMNAPNYHYEECSCYPDSSEITCVCRDNWHGSNRPWVSFNQNLEYQIGYICSGIFGDNPRPNDKTGSCGPVSSNGANGVKGFSFKYGNGVWIGRTKSISSRNGFEMIWDPNGWTGTDNNFSIKQDIVGINEWSGYSGSFVQHPELTGLDCIRPCFWVELIRGRPKENTIWTSGSSISFCGVNSDTVGWSWPDGAELPFTIDKVKLAGNSSLCPVSGWAIYSKDNSVRIGSKGDVFVIREPFISCSPLECRTFFLTQGALLNDKHSNGTIKDRSPYRTLMSCPIGEVPSPYNSRFESVAWSASACHDGINWLTIGISGPDNGAVAVLKYNGIITDTIKSWRNNILRTQESECACVNGSCFTVMTDGPSNGQASYKIFRIEKGKIVKSVEMNAPNYHYEECSCYPDSSEITCVCRDNWHGSNRPWVSFNQNLEYQIGYICSGIFGDNPRPNDKTGSCGPVSSNGANGVKGFSFKYGNGVWIGRTKSISSRNGFEMIWDPNGWTGTDNNFSIKQDIVGINEWSGYSGSFVQHPELTGLDCIRPCFWVELIRGRPKENTIWTSGSSISFCGVNSDTVGWSWPDGAELPFTIDK

~~~~~~S~B~~~SEEEEEEE~~HHHHTTTS~~EEEEEEEEEE~SS~EEEEEEEEEEETTSGGGTTTT~S~~TT~EEEEEETTS~~~TTT~EEEEE~SEEEEEE~SSSEEEEEEES~TTS~EEEEEETTEEEEEEE~SSSS~~B~~SS~~EEETTEEEEEEEES~SSS~~EEEEEEEETTEEEEEEE~~~TT~~~~S~EEEEETTEEEEE~~~~SS~SS~EEEEEETT~~EEEEE~~~SS~~SSS~~SS~~~~SS~~~TT~SS~~~~EEEEETTEEEEEE~S~SSSSEEEEEEEETTTTT~~~~~~SEEEEEEEEEEE~~~EEEEEE~HHHH~~SSBEEEEEEEEEEETTTSSSS~EEEEEEEEEEESS~~~~~~~~~~~~SS~GGG~~~~~~~S~B~~~SEEEEEEE~~HHHHHTTS~~EEEEEEEEEE~SS~EEEEEEEEEEETTSGGGTTTT~S~~TT~EEEEEETTS~~~TTT~EEEEE~SEEEEEE~SSSEEEEEEES~TTS~EEEEEETTEEEEEEE~SSSS~~B~~SEE~EEETTEEEEEEEES~SSS~~EEEEEEEETTEEEEEEE~~~TT~~~EEEEEEEETTEEEEEEE~TTT~SS~EEEEE~TT~~EEEEE~~~SS~~SSS~~~S~S~~SS~~~TT~SS~~~~EEEEETTEEEEEE~S~SSSSEEEEEEEETTTTT~~~~~~SEEEEEEEEEEE~~~EEEEEE~HHHH~~SSBEEEEEEEEEEETTTSSSS~EEEEEEEEEEESS~~~~~~~~~~~~SS~GGG~~~~~~~S~B~~~SEEEEEEE~~HHHHHTTS~~EEEEEEEEEE~SS~EEEEEEEEEEETTSGGGTTTT~S~~SS~EEEEEETTS~~~TTT~EEEEE~SEEEEEE~SS~EEEEEEES~TTT~EEEEEETTEEEEEEE~SSSS~~B~~SSB~EEETTEEEEEEEES~SSS~~EEEEEEEETTEEEEEEE~~~TT~~~~S~EEEEETTEEEEE~~~TTT~SS~EEEEE~TT~~EEEEE~~~SS~~SSS~~SS~~~~SS~~~TT~SS~~~~~EEEETTEEEEEE~S~SSSSEEEEEEEETTTTT~~~~~~SEEEEEEEEEEE~~~EEEEEE~HHHH~SSSBEEEEEEEEEEETTTSSSS~EEEEEEEEEEESS~~~~~~~~~~~~SS~GGG~~~~~~~S~B~~~SEEEEEEE~~HHHHHTTS~~EEEEEEEEEE~SS~EEEEEEEEEEETTSGGGTTTT~S~~TT~EEEEEETTS~~~TTT~EEEEE~SEEEEEE~SSSEEEEEEES~TTT~EEEEEETTEEEEEEE~SSSS~~B~~SEE~EEETTEEEEEEEES~SSS~~EEEEEEEETTEEEEEEE~~~TT~~~~S~EEEE~SS~EEEE~~~TTT~SS~EEEEE~TT~~EEEEE~~~SS~~SSS~~~S~~~~SS~~~TT~SS~~~~~EEEETTEEEEEE~S~SSSSEEEEEEEETTTTT~~~~~~SEEEEEEEEEEE~~~EEEEEE~HHHH~~SSBEEEEEEEEEEETTTSSSS~EEEEEEEEEEESS~~~~~~~~~~~~SS~GGG~

V K L A G N S S L C P V S G W A I Y S K D N S V R I G S K G D V F V I R E P F I S C S P L E C R T F F L T Q G A L L N D K H S N G T I K D R S P Y R T L M S C P I G E V P S P Y N S R F E S V A W S A S A C H D G I N W L T I G I S G P D N G A V A V L K Y N G I I T D T I K S W R N N I L R T Q E S E C A C V N G S C F T V M T D G P S N G Q A S Y K I F R I E K G K I V K S V E M N A P N Y H Y E E C S C Y P D S S E I T C V C R D N W H G S N R P W V S F N Q N L E Y Q I G Y I C S G I F G D N P R P N D K T G S C G P V S S N G A N G V K G F S F K Y G N G V W I G R T K S I S S R N G F E M I W D P N G W T G T D N N F S I K Q D I V G I N E W S G Y S G S F V Q H P E L T G L D C I R P C F W V E L I R G R P K E N T I W T S G S S I S F C G V N S D T V G W S W P D G A E L P F T I D K V K L A G N S S L C P V S G W A I Y S K D N S V R I G S K G D V F V I R E P F I S C S P L E C R T F F L T Q G A L L N D K H S N G T I K D R S P Y R T L M S C P I G E V P S P Y N S R F E S V A W S A S A C H D G I N W L T I G I S G P D N G A V A V L K Y N G I I T D T I K S W R N N I L R T Q E S E C A C V N G S C F T V M T D G P S N G Q A S Y K I F R I E K G K I V K S V E M N A P N Y H Y E E C S C Y P D S S E I T C V C R D N W H G S N R P W V S F N Q N L E Y Q I G Y I C S G I F G D N P R P N D K T G S C G P V S S N G A N G V K G F S F K Y G N G V W I G R T K S I S S R N G F E M I W D P N G W T G T D N N F S I K Q D I V G I N E W S G Y S G S F V Q H P E L T G L D C I R P C F W V E L I R G R P K E N T I W T S G S S I S F C G V N S D T V G W S W P D G A E L P F T I D K V K L A G N S S L C P V S G W A I Y S K D N S V R I G S K G D V F V I R E P F I S C S P L E C R T F F L T Q G A L L N D K H S N G T I K D R S P Y R T L M S C P I G E V P S P Y N S R F E S V A W S A S A C H D G I N W L T I G I S G P D N G A V A V L K Y N G I I T D T I K S W R N N I L R T Q E S E C A C V N G S C F T V M T D G P S N G Q A S Y K I F R I E K G K I V K S V E M N A P N Y H Y E E C S C Y P D S S E I T C V C R D N W H G S N R P W V S F N Q N L E Y Q I G Y I C S G I F G D N P R P N D K T G S C G P V S S N G A N G V K G F S F K Y G N G V W I G R T K S I S S R N G F E M I W D P N G W T G T D N N F S I K Q D I V G I N E W S G Y S G S F V Q H P E L T G L D C I R P C F W V E L I R G R P K E N T I W T S G S S I S F C G V N S D T V G W S W P D G A E L P F T I D K V K L A G N S S L C P V S G W A I Y S K D N S V R I G S K G D V F V I R E P F I S C S P L E C R T F F L T Q G A L L N D K H S N G T I K D R S P Y R T L M S C P I G E V P S P Y N S R F E S V A W S A S A C H D G I N W L T I G I S G P D N G A V A V L K Y N G I I T D T I K S W R N N I L R T Q E S E C A C V N G S C F T V M T D G P S N G Q A S Y K I F R I E K G K I V K S V E M N A P N Y H Y E E C S C Y P D S S E I T C V C R D N W H G S N R P W V S F N Q N L E Y Q I G Y I C S G I F G D N P R P N D K T G S C G P V S S N G A N G V K G F S F K Y G N G V W I G R T K S I S S R N G F E M I W D P N G W T G T D N N F S I K Q D I V G I N E W S G Y S G S F V Q H P E L T G L D C I R P C F W V E L I R G R P K E N T I W T S G S S I S F C G V N S D T V G W S W P D G A E L P F T I D K

BS

UNSTRUCTURED

2HV7

NFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFEYRVSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTSNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFEYRVSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTSNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFEYRVSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTSNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFEYRVSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTSNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFEYRVSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTSNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFEYRVSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTSNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFEYRVSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTSNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFEYRVSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTS

~~~~~EE~~~SGGGHHHHHTBHHHHHHHHHHHHHHHHHTT~~TT~~~~~~HHHHHHHHHHHHHHHHHHHS~~~~S~~~SS~THHHHHHHHHHHHHHHHHTTTS~GGGTTHHHHHHHHHHTSS~BTTTTEE~HHHHHHHHHHHHHHHHTTSS~GGGTTHHHHTHHHHHHHHHHHHHHHS~~EESGGGGTT~SSSS~~HHHHHHHHHTTT~SS~~GGGGG~HHHHHHHTTT~HHHHHHHHHHHH~~S~HHHHSHHHHHHTTSS~HHHHHHHHHHHHHHHTTT~HHHHTT~EE~SSS~~SB~~~~~~~~EE~~~SHHHHHHHHSBHHHHHHHHHHHHHHHHSTT~~TT~~~~~~HHHHHHHHHHHHHHHHHHTS~~~~~S~SS~~THHHHHHHHHHHHHHHHHHTTS~STTTTSHHHHHHHHHTSS~BTTTTEE~HHHHHHHHHHHHHHHHTTSS~GGGHHHHHHTHHHHHHHHHHHHHHHHT~EESSS~TTTSS~SS~~HHHHHHHHHTTT~SS~~GGGTT~HHHHHHHTTT~HHHHHHHHHHHHS~S~HHHH~HHHHHHTTSS~HHHHHHHHHHHHHHHTTT~HHHHTT~EE~SSS~SSB~~~~~~~~EE~~~SHHHHHHHHHBHHHHHHHHHHHHHHHHTTT~~TT~~~~~~HHHHHHHHHHHHHHHHHHHS~~~~~S~SS~~TTHHHHHHHHHHHHHHHHTTTS~GGGGGGHHHHHHHHHTSS~BTTTTEE~HHHHHHHHHHHHHHHHTTSS~GGGHHHHHHTHHHHHHHHHHHHHHHHT~EESSS~TTTSS~SS~SHHHHHHHHHTTT~SS~~GGGTT~HHHHHHHTTT~HHHHHHHHHHHHS~S~HHHH~HHHHHHTTSS~HHHHHHHHHHHHHHHTTT~HHHHTT~EE~SSS~SSB~~~~~~~~EE~~~SGGGHHHHHTBHHHHHHHHHHHHHHHHHTT~~TT~~~~~~HHHHHHHHHHHHHHHHHHHS~~~~S~~SSS~THHHHHHHHHHHHHHHHHTTTS~GGGGGGHHHHHHHHHTSS~BTTTTEE~HHHHHHHHHHHHHHHHTTSS~GGGTTHHHHTHHHHHHHHHHHHHHHT~~EESGGGTTT~SSSS~~HHHHHHHHHTTT~SS~~GGGGG~HHHHHHHGGG~HHHHHHHHHHHH~~S~HHHH~HHHHHHHTSS~HHHHHHHHHHHHHHTTTS~HHHHTT~EE~SSS~~SB~~~~~~~~EE~~~SHHHHHHHHHBHHHHHHHHHHHHHHHHSTT~~TTS~~~~~HHHHHHHHHHHHHHHHHHTS~~~~~S~SS~~THHHHHHHHHHHTHHHHHTTTS~GGGGGGHHHHHHHHHTTS~BTTTTEE~HHHHHHHHHHHHGGGTTTSS~GGGHHHHHHTTHHHHHHHHHHHHHHHT~EESSS~TTTSS~SS~~HHHHHHHHHTTT~SS~~GGGTT~HHHHHHHTTT~HHHHHHHHHHHH~~S~HHHH~HHHHHHTTSS~HHHHHHHHHHHHHHHTTT~HHHHTT~EE~SSS~SSB~~~~~~~~EE~~~SGGGHHHHHTBHHHHHHHHHHHHHHHHHTT~~TT~~~~~~HHHHHHHHHHHHHHHHHHHS~~~~S~~~SS~THHHHHHHHHHHHHHHHHTTTS~GGGGGGHHHHHHHHHTSS~BTTTTEE~HHHHHHHHHHHHHHHHTTSS~GGGGTHHHHTHHHHHHHHHHHHHHHS~~EESTTHHHHSSSSS~SHHHHHHHHHTTT~SS~~GGGTT~HHHHHHHTTT~HHHHHHHHHHHH~~S~HHHHTHHHHHHHTSS~HHHHHHHHHHHHHHHTTT~HHHHTT~EE~SSS~~SB~~~~~~~~EE~~~SHHHHHHHHHBHHHHHHHHHHHHHHHTTTT~~TT~~~~~~TTHHHHHHHHHHHHHHHHHS~~~~~S~SS~~THHHHHHHHHHHHHHHHHHTTS~GGGTTSHHHHHHHHHTSS~BTTTTEE~HHHHHHHHHHHHHHHHTTSS~GGGHHHHHHTTHHHHHHHHHHHHHHHT~EESSTTTTTSS~SS~~HHHHHHHHHTTT~SS~~GGGTTSHHHHHTTTTT~HHHHHHHHHHHH~~S~HHHH~HHHHHHHT~S~HHHHHHHHHHHHHHTTTT~HHHHTT~EE~SSS~SSB~~~~~~~~EE~~~SGGGHHHHHTBHHHHHHHHHHHHHHHHHTT~~TT~~~~~~HHHHHHHHHHHHHHHHHHHS~~~~S~~~SS~THHHHHHHHHHHHHHHHHTTTS~GGGGGGHHHHHHHHHTSS~BTTTTEE~HHHHHHHHHHHHHHHHTTSS~GGGTTHHHHTHHHHHHHHHHHHHHHTT~EESGGGGTSSSSSS~SHHHHHHHHHTTT~SS~~GGGTT~HHHHHHHTTT~HHHHHHHHHHHH~~S~HHHH~HHHHHHHHSS~HHHHHHHHHHHHHHHTTT~HHHHTT~EE~SSS~~SB~~~

N F I I P K K E I H T V P D M G K W K R S Q A Y A D Y I G F I L T L N E G V K G K K L T F E Y R V S E A I E K L V A L L N T L D R W I D E T P P V D Q P S R F G N K A Y R T W Y A K L D E E A E N L V A T V V P T H L A A A V P E V A V Y L K E S V G N S T R I D Y G T G H E A A F A A F L C C L C K I G V L R V D D Q I A I V F K V F N R Y L E V M R K L Q K T Y R M E P A G S Q G V W G L D D F Q F L P F I W G S S Q L I D H P Y L E P R H F V D E K A V N E N H K D Y M F L E C I L F I T E M K T G P F A E H S N Q L W N I S A V P S W S K V N Q G L I R M Y K A E C L E K F P V I Q H F K F G S L L P I H P V T S N F I I P K K E I H T V P D M G K W K R S Q A Y A D Y I G F I L T L N E G V K G K K L T F E Y R V S E A I E K L V A L L N T L D R W I D E T P P V D Q P S R F G N K A Y R T W Y A K L D E E A E N L V A T V V P T H L A A A V P E V A V Y L K E S V G N S T R I D Y G T G H E A A F A A F L C C L C K I G V L R V D D Q I A I V F K V F N R Y L E V M R K L Q K T Y R M E P A G S Q G V W G L D D F Q F L P F I W G S S Q L I D H P Y L E P R H F V D E K A V N E N H K D Y M F L E C I L F I T E M K T G P F A E H S N Q L W N I S A V P S W S K V N Q G L I R M Y K A E C L E K F P V I Q H F K F G S L L P I H P V T S N F I I P K K E I H T V P D M G K W K R S Q A Y A D Y I G F I L T L N E G V K G K K L T F E Y R V S E A I E K L V A L L N T L D R W I D E T P P V D Q P S R F G N K A Y R T W Y A K L D E E A E N L V A T V V P T H L A A A V P E V A V Y L K E S V G N S T R I D Y G T G H E A A F A A F L C C L C K I G V L R V D D Q I A I V F K V F N R Y L E V M R K L Q K T Y R M E P A G S Q G V W G L D D F Q F L P F I W G S S Q L I D H P Y L E P R H F V D E K A V N E N H K D Y M F L E C I L F I T E M K T G P F A E H S N Q L W N I S A V P S W S K V N Q G L I R M Y K A E C L E K F P V I Q H F K F G S L L P I H P V T S N F I I P K K E I H T V P D M G K W K R S Q A Y A D Y I G F I L T L N E G V K G K K L T F E Y R V S E A I E K L V A L L N T L D R W I D E T P P V D Q P S R F G N K A Y R T W Y A K L D E E A E N L V A T V V P T H L A A A V P E V A V Y L K E S V G N S T R I D Y G T G H E A A F A A F L C C L C K I G V L R V D D Q I A I V F K V F N R Y L E V M R K L Q K T Y R M E P A G S Q G V W G L D D F Q F L P F I W G S S Q L I D H P Y L E P R H F V D E K A V N E N H K D Y M F L E C I L F I T E M K T G P F A E H S N Q L W N I S A V P S W S K V N Q G L I R M Y K A E C L E K F P V I Q H F K F G S L L P I H P V T S N F I I P K K E I H T V P D M G K W K R S Q A Y A D Y I G F I L T L N E G V K G K K L T F E Y R V S E A I E K L V A L L N T L D R W I D E T P P V D Q P S R F G N K A Y R T W Y A K L D E E A E N L V A T V V P T H L A A A V P E V A V Y L K E S V G N S T R I D Y G T G H E A A F A A F L C C L C K I G V L R V D D Q I A I V F K V F N R Y L E V M R K L Q K T Y R M E P A G S Q G V W G L D D F Q F L P F I W G S S Q L I D H P Y L E P R H F V D E K A V N E N H K D Y M F L E C I L F I T E M K T G P F A E H S N Q L W N I S A V P S W S K V N Q G L I R M Y K A E C L E K F P V I Q H F K F G S L L P I H P V T S N F I I P K K E I H T V P D M G K W K R S Q A Y A D Y I G F I L T L N E G V K G K K L T F E Y R V S E A I E K L V A L L N T L D R W I D E T P P V D Q P S R F G N K A Y R T W Y A K L D E E A E N L V A T V V P T H L A A A V P E V A V Y L K E S V G N S T R I D Y G T G H E A A F A A F L C C L C K I G V L R V D D Q I A I V F K V F N R Y L E V M R K L Q K T Y R M E P A G S Q G V W G L D D F Q F L P F I W G S S Q L I D H P Y L E P R H F V D E K A V N E N H K D Y M F L E C I L F I T E M K T G P F A E H S N Q L W N I S A V P S W S K V N Q G L I R M Y K A E C L E K F P V I Q H F K F G S L L P I H P V T S N F I I P K K E I H T V P D M G K W K R S Q A Y A D Y I G F I L T L N E G V K G K K L T F E Y R V S E A I E K L V A L L N T L D R W I D E T P P V D Q P S R F G N K A Y R T W Y A K L D E E A E N L V A T V V P T H L A A A V P E V A V Y L K E S V G N S T R I D Y G T G H E A A F A A F L C C L C K I G V L R V D D Q I A I V F K V F N R Y L E V M R K L Q K T Y R M E P A G S Q G V W G L D D F Q F L P F I W G S S Q L I D H P Y L E P R H F V D E K A V N E N H K D Y M F L E C I L F I T E M K T G P F A E H S N Q L W N I S A V P S W S K V N Q G L I R M Y K A E C L E K F P V I Q H F K F G S L L P I H P V T S N F I I P K K E I H T V P D M G K W K R S Q A Y A D Y I G F I L T L N E G V K G K K L T F E Y R V S E A I E K L V A L L N T L D R W I D E T P P V D Q P S R F G N K A Y R T W Y A K L D E E A E N L V A T V V P T H L A A A V P E V A V Y L K E S V G N S T R I D Y G T G H E A A F A A F L C C L C K I G V L R V D D Q I A I V F K V F N R Y L E V M R K L Q K T Y R M E P A G S Q G V W G L D D F Q F L P F I W G S S Q L I D H P Y L E P R H F V D E K A V N E N H K D Y M F L E C I L F I T E M K T G P F A E H S N Q L W N I S A V P S W S K V N Q G L I R M Y K A E C L E K F P V I Q H F K F G S L L P I H P V T S

AH

UNSTRUCTURED

2D6K

ALFSAQSPYINPIIPFTGPIQGGLQEGLQVTLQGTTKSFAQRFVVNFQNSGNDIAFHFNPRFEEGGYVVCNTKQNGQWGPEERKMQMPFQKGMPFELCFLVQRSEFKVMVNKKFFVQYQHRVPYHLVDTIAVSGCLKLSFITFQTQNAQSPYINPIIPFTGPIQGGLQEGLQVTLQGTTKSFAQRFVVNFQNSFNGNDIAFHFNPRFEEGGYVVCNTKQNGQWGPEERKMQMPFQKGMPFELCFLVQRSEFKVMVNKKFFVQYQHRVPYHLVDTIAVSGCLKLSFITFQT

~~EESS~~EES~~SSEEEE~TT~~~TT~EEEEEEEE~TT~~BEEEEEE~~~~~EEEEEEEE~STT~EEEEEEEETTEE~~~EEE~~~~~~TT~EEEEEEEE~SSEEEEEETTEEEEEEE~SS~GGG~~EEEEEESEEEEEEEEEE~~~~~~EES~~SSEEEE~TT~~~TT~EEEEEEEE~TT~~BEEEEEE~GGGTT~EEEEEEEE~STT~EEEEEEEETTEE~~~EEE~~~~~~TTSEEEEEEEE~SSEEEEEHHTEEEEEEE~SS~GGG~~EEEEEESEEEEEEEEE~

A L F S A Q S P Y I N P I I P F T G P I Q G G L Q E G L Q V T L Q G T T K S F A Q R F V V N F Q N S G N D I A F H F N P R F E E G G Y V V C N T K Q N G Q W G P E E R K M Q M P F Q K G M P F E L C F L V Q R S E F K V M V N K K F F V Q Y Q H R V P Y H L V D T I A V S G C L K L S F I T F Q T Q N A Q S P Y I N P I I P F T G P I Q G G L Q E G L Q V T L Q G T T K S F A Q R F V V N F Q N S F N G N D I A F H F N P R F E E G G Y V V C N T K Q N G Q W G P E E R K M Q M P F Q K G M P F E L C F L V Q R S E F K V M V N K K F F V Q Y Q H R V P Y H L V D T I A V S G C L K L S F I T F Q T

BS

UNSTRUCTURED

4D0A

MELMMAIGYLGLALVLGSLVAKIAEKLKIPDIPLLLLLGLIIGPFLQIIPSDSAMEIFEYAGPIGLIFILLGGAFTMRISLLKRVIKTVVRLDTITFLITLLISGFIFNMVLNLPYTSPVGYLFGAITAATDPATLIPVFSRVRTNPEVAITLEAESIFNDPLGIVSTSVILGLFGLFSSSNPLIDLITLAGGAIVVGLLLAKIYEKIIIHCDFHEYVAPLVLGGAMLLLYVGDDLLPSICGYGFSGYMAVAIMGLYLGDALFRADDIDYKYIVSFCDDLSLLARVFIFVFLGACIKLSMLENYFIPGLLVALGSIFLARPLGVFLGLIGSKHSFKEKLYFALEGPRGVVPAALAVTVGIEILKNADKIPASITKYITPTDIAGTIIIGTFMTILLSVILEASWAGMLALKLLGEYKPK

~~HHHHHHHHHHHHHHHHHHHHHHHEE~~~HHHHHHHHHHHTTTTTT~~~HHHHHHHHHHHHHHHHHHHHHHHHHTS~SGGGGSSHHHHHHHHHHHHHHHHHHHHHHHHHHHT~~SS~SHHHHHHHHHH~~~~TTTHHHHTT~~~~SSHHHHHHHHHHHHHHHHHHHHHHHHHHS~~S~~S~SSHHHHHHHHHHHHHHHHHHHHHHHHHHH~~~~TTHHHHHHHHHHHHHHHHHTHHHHHTS~~~~HHHHHHHHHHHHHHHHHHH~SSSSTTHHHHHHHHHHHHHHHHHHHHHHHS~SSTTTTTHHHHHHHHHHHHHTHHHHHHHHHHTT~~~~~SSHHHHTT~~~~~SHHHHHHHHHHHHHHHHHHH~~TTSSSSS~THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTT~TT~~~~

M E L M M A I G Y L G L A L V L G S L V A K I A E K L K I P D I P L L L L L G L I I G P F L Q I I P S D S A M E I F E Y A G P I G L I F I L L G G A F T M R I S L L K R V I K T V V R L D T I T F L I T L L I S G F I F N M V L N L P Y T S P V G Y L F G A I T A A T D P A T L I P V F S R V R T N P E V A I T L E A E S I F N D P L G I V S T S V I L G L F G L F S S S N P L I D L I T L A G G A I V V G L L L A K I Y E K I I I H C D F H E Y V A P L V L G G A M L L L Y V G D D L L P S I C G Y G F S G Y M A V A I M G L Y L G D A L F R A D D I D Y K Y I V S F C D D L S L L A R V F I F V F L G A C I K L S M L E N Y F I P G L L V A L G S I F L A R P L G V F L G L I G S K H S F K E K L Y F A L E G P R G V V P A A L A V T V G I E I L K N A D K I P A S I T K Y I T P T D I A G T I I I G T F M T I L L S V I L E A S W A G M L A L K L L G E Y K P K

AH

UNSTRUCTURED

3PJK

SAVKAARYGKDNVRVYKVHKDEKTGVQTVYEMTVCVLLEGEIETSYTKADNSVIVATDSIKNTIYITAKQNPVTPPELFGSILGTHFIEKYNHIHAAHVNIVCHRWTRMDIDGKPHPHSFIRDSEEKRNVQVDVVEGKGIDIKSSLSGLTVLKSTNSQFWGFLRDEYTTLKETWDRILSTDVDATWQWKNFSGLQEVRSHVPKFDATWATAREVTLKTFAEDNSASVQATMYKMAEQILARQQLIETVEYSLPNKHYFEIDLSWHKGLQNTGKNAEVFAPQSDPNGLIKCTVGRS

~~~~~~~EEEEEEEEEEEEE~TTT~~EEEEEEEEEEEEEES~HHHHHS~~GGG~~~HHHHHHHHHHHHHHS~~~SHHHHHHHHHHHHHHH~TTEEEEEEEEEEE~~EEEEETTEEEEEEEE~~~S~EEEEEEEEETTTEEEEEEEEEEEEEEESSSB~B~S~~~STT~~~~~BSS~~EEEEEEEEEEE~~BSSHHHHHHTHHHHHHHHHHHHHHHHHHHHH~~BS~HHHHHHHHHHHHHHH~TTEEEEEEEEEE~~EEE~~~TTTTT~~~SGGG~~~EEE~~S~~EEEEEEEE~~

S A V K A A R Y G K D N V R V Y K V H K D E K T G V Q T V Y E M T V C V L L E G E I E T S Y T K A D N S V I V A T D S I K N T I Y I T A K Q N P V T P P E L F G S I L G T H F I E K Y N H I H A A H V N I V C H R W T R M D I D G K P H P H S F I R D S E E K R N V Q V D V V E G K G I D I K S S L S G L T V L K S T N S Q F W G F L R D E Y T T L K E T W D R I L S T D V D A T W Q W K N F S G L Q E V R S H V P K F D A T W A T A R E V T L K T F A E D N S A S V Q A T M Y K M A E Q I L A R Q Q L I E T V E Y S L P N K H Y F E I D L S W H K G L Q N T G K N A E V F A P Q S D P N G L I K C T V G R S

BS

AH

5FZV

GLIESIACIQKGLPCMEHSDCCRGVCEALFCQ

~~SSSSS~B~TTSB~SHTTTBTTS~EETTEE~

G L I E S I A C I Q K G L P C M E H S D C C R G V C E A L F C Q

T

BEND

4RZS

PVTLYDVAEYAGVSYQTVSRVVNQASHVSAKTREKVEAAMAELNYIPNRSLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERSGVEACKAAVHNLLAQRVSGLIINYPLDDQDAIAVEAACTNVPALFLTASDQTPLNSIIFSHEDGTRLGVEHLVALGHQQIALLAGPLSSVDARLRLAGWHKYLTRNQIQPIAEREGDWSAMSGFQQTMQMLNEGIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGYDDTEDSSCYIPPLTTIKQDFRLLGQTSVDRLLQLSQGQAVKGNQLLPVSLVKRKTTLAPNTQTASPRALADSLMQLARQVSRLESPVTLYDVAEYAGVSYQTVSRVVNQASHVSAKTREKVEAAMAELNYIPNRVAQQLAGKQSLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERSGVEACKAAVHNLLAQRVSGLIINYPLDDQDAIAVEAACTNVPALFLTASDQTPLNSIIFSHEDGTRLGVEHLVALGHQQIALLAGPLSSVDARLRLAGWHKYLTRNQIQPIAEREGDWSAMSGFQQTMQMLNEGIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGYDDTEDSSCYIPPLTTIKQDFRLLGQTSVDRLLQLSQGQAVKGNQLLPVSLVKRKTTLAPNTQTASPRALADSLMQLARQVSRLESLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERSGVEACKAAVHNLLAQRVSGLIINYPLDDQDAIAVEAACTNVPALFLTASDQTPLNSIIFSHEDGTRLGVEHLVALGHQQIALLAGPLSSVDARLRLAGWHKYLTRNQIQPIAEREGDWSAMSGFQQTMQMLNEGIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGYDDTEDSSCYIPPLTTIKQDFRLLGQTSVDRLLQLSQGQAVKGNQLLPVSLVKRKTTLAPNTQTASPRALADSLMQLARQVSRLESSLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERSGVEACKAAVHNLLAQRVSGLIINYPLDDQDAIAVEAACTNVPALFLTASDQTPLNSIIFSHEDGTRLGVEHLVALGHQQIALLAGPLSSVDARLRLAGWHKYLTRNQIQPIAEREGDWSAMSGFQQTMQMLNEGIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGYDDTEDSSCYIPPLTTIKQDFRLLGQTSVDRLLQLSQGQAVKGNQLLPVSLVKRKTTLAPNTQTASPRALADSLMQLARQVSRL

~~~HHHHHHHHT~~HHHHHHHHH~~SS~~TTTHHHHHHHHHTTT~~~~~~~EEEEEEE~TTSHHHHHHHHHHHHHHHHTT~EEEEEEE~SSSHHHHHHHHHHHHHTT~SEEEEES~~~HHHHHHHHHHH~SS~EEESSS~TT~SS~EEEE~HHHHHHHHHHHHHHTT~~~EEEEE~~TTSHHHHHHHHHHHHHHHHTT~~~SEEEE~~SSHHHHHHHHHHHHHTT~~~SEEEESSHHHHHHHHHHHHHTT~~BTTTBEEE~SB~~GGGGGSSS~~~EEE~~HHHHHHHHHHHHHHHTTT~S~~SEEEE~~EEE~~TT~~~~TTS~~~HHHHHHHHHHHHHHHHT~~~~~~HHHHHHHHT~~HHHHHHHTT~SSSS~TTTHHHHHHHHHTTT~~~SSSSSSS~SS~~~EEEEEEE~TTSHHHHHHHHHHHHHHHHTT~EEEEEEE~S~SHHHHHHHHHHHHHTT~SEEEEES~~~HHHHHHHHHHT~SS~EEESSS~SS~SS~EEEE~HHHHHHHHHHHHHHTT~~~EEEEE~~TTSHHHHHHHHHHHHHHHTTT~~~SEEEE~~SSHHHHHHHHHHHHHTT~~~SEEEESSHHHHHHHHHHHHHTT~~BTTTBEEE~SB~~GGGGGSSS~~~EEE~~HHHHHHHHHHHHHHHTTT~S~~SEEEE~~EEE~~TT~~~~~~~~~~HHHHHHHHHHHHHHHHT~~~~EEEEEEE~TTSHHHHHHHHHHHHHHHHTT~EEEEEEE~S~SHHHHHHHHHHHHHTT~SEEEEES~~~HHHHHHHHHHT~SS~EEESSS~TT~SS~EEEE~HHHHHHHHHHHHHHTT~~SEEEEE~~TTSHHHHHHHHHHHHHHHHTT~~~SEEEE~~SSHHHHHHHHHHHHHTT~~~SEEEESSHHHHHHHHHHHHHTT~~BTTTBEEE~SB~~GGGGGSSS~~~EEE~~HHHHHHHHHHHHHHHTTT~S~~SEEEE~~EEE~~TT~~~S~~~SS~HHHHHHHHHHHHHHHHTS~~~~EEEEEES~TTSHHHHHHHHHHHHHHHHTT~EEEEEE~~S~SHHHHHHHHHHHHHTT~SEEEEES~~~HHHHHHHHHHH~SS~EEESSS~TT~SS~EEEE~HHHHHHHHHHHHHHTT~~~EEEEE~~TT~HHHHHHHHHHHHHHHHTT~~~SEEEE~~SSHHHHHHHHHHHHHTT~~~SEEEESSHHHHHHHHHHHHHTT~~BTTTBEEE~SB~~GGGGGSSS~~~EEE~~HHHHHHHHHHHHHHHTTT~S~~SEEEE~~EEE~~TT~~~~~~~~~~HHHHHHHHHHHHHHHHH~

P V T L Y D V A E Y A G V S Y Q T V S R V V N Q A S H V S A K T R E K V E A A M A E L N Y I P N R S L L I G V A T S S L A L H A P S Q I V A A I K S R A D Q L G A S V V V S M V E R S G V E A C K A A V H N L L A Q R V S G L I I N Y P L D D Q D A I A V E A A C T N V P A L F L T A S D Q T P L N S I I F S H E D G T R L G V E H L V A L G H Q Q I A L L A G P L S S V D A R L R L A G W H K Y L T R N Q I Q P I A E R E G D W S A M S G F Q Q T M Q M L N E G I V P T A M L V A N D Q M A L G A M R A I T E S G L R V G A D I S V V G Y D D T E D S S C Y I P P L T T I K Q D F R L L G Q T S V D R L L Q L S Q G Q A V K G N Q L L P V S L V K R K T T L A P N T Q T A S P R A L A D S L M Q L A R Q V S R L E S P V T L Y D V A E Y A G V S Y Q T V S R V V N Q A S H V S A K T R E K V E A A M A E L N Y I P N R V A Q Q L A G K Q S L L I G V A T S S L A L H A P S Q I V A A I K S R A D Q L G A S V V V S M V E R S G V E A C K A A V H N L L A Q R V S G L I I N Y P L D D Q D A I A V E A A C T N V P A L F L T A S D Q T P L N S I I F S H E D G T R L G V E H L V A L G H Q Q I A L L A G P L S S V D A R L R L A G W H K Y L T R N Q I Q P I A E R E G D W S A M S G F Q Q T M Q M L N E G I V P T A M L V A N D Q M A L G A M R A I T E S G L R V G A D I S V V G Y D D T E D S S C Y I P P L T T I K Q D F R L L G Q T S V D R L L Q L S Q G Q A V K G N Q L L P V S L V K R K T T L A P N T Q T A S P R A L A D S L M Q L A R Q V S R L E S L L I G V A T S S L A L H A P S Q I V A A I K S R A D Q L G A S V V V S M V E R S G V E A C K A A V H N L L A Q R V S G L I I N Y P L D D Q D A I A V E A A C T N V P A L F L T A S D Q T P L N S I I F S H E D G T R L G V E H L V A L G H Q Q I A L L A G P L S S V D A R L R L A G W H K Y L T R N Q I Q P I A E R E G D W S A M S G F Q Q T M Q M L N E G I V P T A M L V A N D Q M A L G A M R A I T E S G L R V G A D I S V V G Y D D T E D S S C Y I P P L T T I K Q D F R L L G Q T S V D R L L Q L S Q G Q A V K G N Q L L P V S L V K R K T T L A P N T Q T A S P R A L A D S L M Q L A R Q V S R L E S S L L I G V A T S S L A L H A P S Q I V A A I K S R A D Q L G A S V V V S M V E R S G V E A C K A A V H N L L A Q R V S G L I I N Y P L D D Q D A I A V E A A C T N V P A L F L T A S D Q T P L N S I I F S H E D G T R L G V E H L V A L G H Q Q I A L L A G P L S S V D A R L R L A G W H K Y L T R N Q I Q P I A E R E G D W S A M S G F Q Q T M Q M L N E G I V P T A M L V A N D Q M A L G A M R A I T E S G L R V G A D I S V V G Y D D T E D S S C Y I P P L T T I K Q D F R L L G Q T S V D R L L Q L S Q G Q A V K G N Q L L P V S L V K R K T T L A P N T Q T A S P R A L A D S L M Q L A R Q V S R L

AH

UNSTRUCTURED

2P2O

KSEKEKMLAGHLYNPADLELVKERERARRLVRLYNETLETEYDKRTGLLKELFGSTGERLFIEPNFRCDYGYNIHVGENFFMNFDGVILDVCEVRIGDHCFIGPGVHIYTATHPLDPHERNSGLEYGKPVVIGHNVWIGGRAVINPGVTIGDNAVIASGAVVTKDVPANAVVGGNPAKVIKWLKKSEKEKMLAGHLYNPADLELVKERERARRLVRLYNETLETEYDKRTGLLKELFGSTGERLFIEPNFRCDYGYNIHVGENFFMNFDGVILDVCEVRIGDHCFIGPGVHIYTATHPLDPHERNSGLEYGKPVVIGHNVWIGGRAVINPGVTIGDNAVIASGAVVTKDVPANAVVGGNPAKVIKWLKKSEKEKMLAGHLYNPADLELVKERERARRLVRLYNETLETEYDKRTGLLKELFGSTGERLFIEPNFRCDYGYNIHVGENFFMNFDGVILDVCEVRIGDHCFIGPGVHIYTATHPLDPHERNSGLEYGKPVVIGHNVWIGGRAVINPGVTIGDNAVIASGAVVTKDVPANAVVGGNPAKVIKWLKKSEKEKMLAGHLYNPADLELVKERERARRLVRLYNETLETEYDKRTGLLKELFGSTGERLFIEPNFRCDYGYNIHVGENFFMNFDGVILDVCEVRIGDHCFIGPGVHIYTATHPLDPHERNSGLEYGKPVVIGHNVWIGGRAVINPGVTIGDNAVIASGAVVTKDVPANAVVGGNPAKVIKWLKSEKEKMLAGHLYNPADLELVKERERARRLVRLYNETLETEYDKRTGLLKELFGSTGERLFIEPNFRCDYGYNIHVGENFFMNFDGVILDVCEVRIGDHCFIGPGVHIYTATHPLDPHERNSGLEYGKPVVIGHNVWIGGRAVINPGVTIGDNAVIASGAVVTKDVPANAVVGGNPAKVIKWLKKSEKEKMLAGHLYNPADLELVKERERARRLVRLYNETLETEYDKRTGLLKELFGSTGERLFIEPNFRCDYGYNIHVGENFFMNFDGVILDVCEVRIGDHCFIGPGVHIYTATHPLDPHERNSGLEYGKPVVIGHNVWIGGRAVINPGVTIGDNAVIASGAVVTKDVPANAVVGGNPAKVIKWLK

~~HHHHHHHT~~B~TT~HHHHHHHHHHHHHHHHHHHS~TT~HHHHHHHHHHHSSB~~S~EEE~S~EEES~STTEEE~TTEEE~SSEEEE~SS~EEE~TT~EE~TT~EEE~EE~~SSHHHHHT~~BEE~~EEE~SS~EE~TT~EE~TT~EE~TT~EE~TT~EE~S~B~TTEEEEETTEEEEEE~~~~HHHHHHHTS~B~TT~HHHHHHHHHHHHHHHHHHHS~TT~HHHHHHHHHHHSSB~~S~EEE~S~EEES~STTEE~~TTEEE~SSEEEE~SS~EEE~SS~EE~TT~EEE~EE~~SSHHHHTT~~BEE~~EEE~SS~EE~TT~EE~TT~EE~TT~EE~TT~EE~S~B~TTEEEEETTEEEEEE~~~~HHHHHHHT~~B~TT~HHHHHHHHHHHHHHHHHHTS~TT~HHHHHHHHHHHSSB~~S~EEE~S~EEES~STTEEE~TTEEE~SSEEEE~SS~EEE~TT~EE~TT~EEE~EE~~SSHHHHHTT~BEE~~EEE~SS~EE~TT~EE~TT~EE~TT~EE~TT~EE~S~B~TTEEEEETTEEEEEE~~~~HHHHHHHTS~B~TT~HHHHHHHHHHHHHHHHHHHS~TT~HHHHHHHHHHHSSB~~S~EEE~S~EEES~STTEEE~TTEEE~TTEEEE~SS~EEE~TT~EE~TT~EEE~EE~~SSHHHHHHT~BEE~~EEE~SS~EE~TT~EE~TT~EE~TT~EE~TT~EE~S~B~TTEEEEETTEEEEEE~~~HHHHHHHT~~B~TT~HHHHHHHHHHHHHHHHHHHS~TT~HHHHHHHHHHHSSB~~S~EEE~S~EEES~STTEEE~TTEEE~SSEEEE~SS~EEE~SS~EE~TT~EEE~EE~~SSHHHHTT~~BEE~~EEE~SS~EE~TT~EE~TT~EE~TT~EE~TT~EE~S~B~TTEEEEETTEEEEEE~~~~HHHHHHTT~~B~TT~HHHHHHHHHHHHHHHHHHTS~TT~HHHHHHHHHHHSSB~~S~EEE~S~EEES~STTEEE~SSEEE~SSEEEE~SS~EEE~SS~EE~TT~EEE~EE~~SSHHHHHTT~BEE~~EEE~TT~EE~TT~EE~TT~EE~TT~EE~TT~EE~S~B~TTEEEEETTEEEEEE~~

K S E K E K M L A G H L Y N P A D L E L V K E R E R A R R L V R L Y N E T L E T E Y D K R T G L L K E L F G S T G E R L F I E P N F R C D Y G Y N I H V G E N F F M N F D G V I L D V C E V R I G D H C F I G P G V H I Y T A T H P L D P H E R N S G L E Y G K P V V I G H N V W I G G R A V I N P G V T I G D N A V I A S G A V V T K D V P A N A V V G G N P A K V I K W L K K S E K E K M L A G H L Y N P A D L E L V K E R E R A R R L V R L Y N E T L E T E Y D K R T G L L K E L F G S T G E R L F I E P N F R C D Y G Y N I H V G E N F F M N F D G V I L D V C E V R I G D H C F I G P G V H I Y T A T H P L D P H E R N S G L E Y G K P V V I G H N V W I G G R A V I N P G V T I G D N A V I A S G A V V T K D V P A N A V V G G N P A K V I K W L K K S E K E K M L A G H L Y N P A D L E L V K E R E R A R R L V R L Y N E T L E T E Y D K R T G L L K E L F G S T G E R L F I E P N F R C D Y G Y N I H V G E N F F M N F D G V I L D V C E V R I G D H C F I G P G V H I Y T A T H P L D P H E R N S G L E Y G K P V V I G H N V W I G G R A V I N P G V T I G D N A V I A S G A V V T K D V P A N A V V G G N P A K V I K W L K K S E K E K M L A G H L Y N P A D L E L V K E R E R A R R L V R L Y N E T L E T E Y D K R T G L L K E L F G S T G E R L F I E P N F R C D Y G Y N I H V G E N F F M N F D G V I L D V C E V R I G D H C F I G P G V H I Y T A T H P L D P H E R N S G L E Y G K P V V I G H N V W I G G R A V I N P G V T I G D N A V I A S G A V V T K D V P A N A V V G G N P A K V I K W L K S E K E K M L A G H L Y N P A D L E L V K E R E R A R R L V R L Y N E T L E T E Y D K R T G L L K E L F G S T G E R L F I E P N F R C D Y G Y N I H V G E N F F M N F D G V I L D V C E V R I G D H C F I G P G V H I Y T A T H P L D P H E R N S G L E Y G K P V V I G H N V W I G G R A V I N P G V T I G D N A V I A S G A V V T K D V P A N A V V G G N P A K V I K W L K K S E K E K M L A G H L Y N P A D L E L V K E R E R A R R L V R L Y N E T L E T E Y D K R T G L L K E L F G S T G E R L F I E P N F R C D Y G Y N I H V G E N F F M N F D G V I L D V C E V R I G D H C F I G P G V H I Y T A T H P L D P H E R N S G L E Y G K P V V I G H N V W I G G R A V I N P G V T I G D N A V I A S G A V V T K D V P A N A V V G G N P A K V I K W L K

BS

UNSTRUCTURED

3MN7

VAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTEEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELKDGQVITIGNERFRCPEALFQPSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCFPSPREQLMESIRKGKELKQA

~~~EEEEE~SSEEEEEETT~SS~SEEEE~~EEE~~~EETHHHHHGGGGSEEE~SEETTEE~~HHHHHHHHHHHHTTTT~~~GGGS~EEEEE~TT~~HHHHHHHHHHHHHHS~~SEEEEEEHHHHHHHHTT~SSEEEEEE~SS~EEEEEEETTEE~GGG~EEE~~SHHHHHHHHHHHHHHHT~~~~SHHHHHHHHHHHHHT~~~~SSHHHHHHHHHH~STT~EEEE~TTS~EEEESTHHHHHHHTTT~GGGGT~~~~~HHHHHHHHHTTS~TTTHHHHTT~EEEESGGG~STTHHHHHHHHHHHHS~TT~~~~EE~~TTGGGHHHHHHHHHTT~TTTGGGSEEHHHHHHH~TTHHHHH~~~~TTHHHHHHHHH~~~~~~~

V A A L V V D N G S G M C K A G F A G D D A P R A V F P S I V G R P D S Y V G D E A Q S K R G I L T L K Y P I E H G I V T N W D D M E K I W H H T F Y N E L R V A P E E H P V L L T E A P L N P K A N R E K M T Q I M F E T F N T P A M Y V A I Q A V L S L Y A S G R T T G I V L D S G D G V S H T V P I Y E G Y A L P H A I L R L D L A G R D L T D Y L M K I L T E R G Y S F T T T E E R E I V R D I K E K L C Y V A L D F E Q E M A T A A S S S S L E K S Y E L K D G Q V I T I G N E R F R C P E A L F Q P S F L G M E A C G I H E T T Y N S I M K C D V D I R K D L Y A N T V L S G G T T M Y P G I A D R M Q K E I T A L A P S T M K I K I I A P P E R K Y S V W I G G S I L A S L S T F Q Q M W I S K Q E Y D E S G P S I V H R K C F P S P R E Q L M E S I R K G K E L K Q A

AH

BS