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LAMM: MIT Laboratory for Atomistic and Molecular Mechanics 42

4UOP

ITAKNVNDIKGVSVKSNPDYFGAAKGKNLIIVQLESFQRNLTNVKINGQSITPTLDGLQNETMYSNQFFQTVSKSNTADAEWSVYTSTFPSGYYTNTQTYGDRVIPSMPRLLGKNDYKTATFHTNDASFYNRDEFYPAVGFDKFYDRKFFGDEDVIGFSPSDEVLYNKAFPILEEQYKNNQKFYAQLISVSSHMPFDIPKDKQEIDLPSDLKDTELGNYFEAVHYADKQLGEFIQKLKDSGIWDDSVVVFYGDHHIIKTDQLPEEQKKYVNRSTQLKAEPADDYRIPFFLHYPGMENPGEIKNVGGEIDIMPTVMNLLGIKTGDQIMFGTDILNSSNNYVPERYTMPEGSYFTNSYMYQPDESFETGAATNYDGTNKELSSDVKKRFDASRKLLQYSDSYVNNLPLRNDITAKNVNDIKGVSVKSNPDYFGAAKGKNLIIVQLESFQRNLTNVKINGQSITPTLDGLQNETMYSNQFFQTVSKSNTADAEWSVYTSTFPSGYYTNTQTYGDRVIPSMPRLLGKNDYKTATFHTNDASFYNRDEFYPAVGFDKFYDRKFFGDEDVIGFSPSDEVLYNKAFPILEEQYKNNQKFYAQLISVSSHMPFDIPKDKQEIDLPSDLKDTELGNYFEAVHYADKQLGEFIQKLKDSGIWDDSVVVFYGDHHIIKTDQLPEEQKKYVNRSTQLKAEPADDYRIPFFLHYPGMENPGEIKNVGGEIDIMPTVMNLLGIKTGDQIMFGTDILNSSNNYVPERYTMPEGSYFTNSYMYQPDESFETGAATNYDGTNKELSSDVKKRFDASRKLLQYSDSYVNNLPLRN

~~HHHHHHHHT~~B~SS~TTTTTTTT~EEEEEEETT~~GGGSS~EETTEES~HHHHHHTTTSEEESSEE~~~~SSHHHHHHHHHHHSS~~~SSS~HHHHTTTB~~~~HHHHHHTTT~EEEEE~SS~TTGGGHHHHHHHTT~SEEE~TTTS~SSSEETTEE~HHHHHHHHHHHHHHHHHTT~~EEEEEE~~TT~TT~~~~GGG~~~~~~TTTTTSHHHHHHHHHHHHHHHHHHHHHHHHHHTSGGGEEEEEEES~~~~~GGGS~GGGGGGS~~TT~~SSTTHHHHB~~EEEE~TT~~~~EE~~S~EEGGGHHHHHHHHTT~~~TT~~~SS~~GGGBSS~~EEE~SSS~TTEEE~SSEEEE~SSSSTTSEEEETTS~EE~~~HHHHHHHHHHHHHHHHHHHHHHT~~B~~~~~HHHHHHHHT~~B~SS~TTTTTTTT~EEEEEEETT~~GGGSS~EETTEES~HHHHHHTTTSEEESSEE~~~~SSHHHHHHHHHHHSS~~~SSS~HHHHTTTB~~~~HHHHHHTTT~EEEEE~SS~TTGGGHHHHHHHTT~SEEE~HHHH~SSSEETTEE~HHHHHHHHHHHHHHHHHTT~~EEEEEE~~TTSTT~~~~GGG~~~~~~TTTTTSHHHHHHHHHHHHHHHHHHHHHHHHHHTSGGGEEEEEEE~~~~~~GGGS~GGGGGGS~~TT~~SSTTHHHHB~~EEEE~TT~~~~EE~~S~EEGGGHHHHHHHHTT~~~TT~~~SS~~GGGBSS~~EEE~SSS~TTEEE~SSEEEE~SSSSTTSEEEETTS~EE~~~HHHHHHHHHHHHHHHHHHHHHHT~~B~~

I T A K N V N D I K G V S V K S N P D Y F G A A K G K N L I I V Q L E S F Q R N L T N V K I N G Q S I T P T L D G L Q N E T M Y S N Q F F Q T V S K S N T A D A E W S V Y T S T F P S G Y Y T N T Q T Y G D R V I P S M P R L L G K N D Y K T A T F H T N D A S F Y N R D E F Y P A V G F D K F Y D R K F F G D E D V I G F S P S D E V L Y N K A F P I L E E Q Y K N N Q K F Y A Q L I S V S S H M P F D I P K D K Q E I D L P S D L K D T E L G N Y F E A V H Y A D K Q L G E F I Q K L K D S G I W D D S V V V F Y G D H H I I K T D Q L P E E Q K K Y V N R S T Q L K A E P A D D Y R I P F F L H Y P G M E N P G E I K N V G G E I D I M P T V M N L L G I K T G D Q I M F G T D I L N S S N N Y V P E R Y T M P E G S Y F T N S Y M Y Q P D E S F E T G A A T N Y D G T N K E L S S D V K K R F D A S R K L L Q Y S D S Y V N N L P L R N D I T A K N V N D I K G V S V K S N P D Y F G A A K G K N L I I V Q L E S F Q R N L T N V K I N G Q S I T P T L D G L Q N E T M Y S N Q F F Q T V S K S N T A D A E W S V Y T S T F P S G Y Y T N T Q T Y G D R V I P S M P R L L G K N D Y K T A T F H T N D A S F Y N R D E F Y P A V G F D K F Y D R K F F G D E D V I G F S P S D E V L Y N K A F P I L E E Q Y K N N Q K F Y A Q L I S V S S H M P F D I P K D K Q E I D L P S D L K D T E L G N Y F E A V H Y A D K Q L G E F I Q K L K D S G I W D D S V V V F Y G D H H I I K T D Q L P E E Q K K Y V N R S T Q L K A E P A D D Y R I P F F L H Y P G M E N P G E I K N V G G E I D I M P T V M N L L G I K T G D Q I M F G T D I L N S S N N Y V P E R Y T M P E G S Y F T N S Y M Y Q P D E S F E T G A A T N Y D G T N K E L S S D V K K R F D A S R K L L Q Y S D S Y V N N L P L R N

AH

UNSTRUCTURED

5NEB

GANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFLYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKGTPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQSALVKNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWGANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFLYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKGTPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQSALVKNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGC

~~~~~EEEEE~~BTTTBEE~~~SS~~~GGGGEESHHHHHHHHHHHHHT~~EEEEE~TT~~~~~B~TTS~B~HHHHHHHTTS~SEEEEEEE~~HHHHTTSEE~S~SEEE~EEEEEESS~S~~SHHHHHH~SSSEEEEBTTSHHHHHHHH~~~HHHHHHHHHHHSGGGTTSBSSHHHHHHHHHHSSEEEEEEHHHHHHHHHH~TTEEEES~~S~~EEEEEEE~TT~HHHHHHHHHHHHHHHTTHHHHHHHHH~~~~~~EEEEE~~BTTTBEE~~~SS~~~GGGGEESHHHHHHHHHHHHHT~~EEEEE~TT~~~~~B~TTS~B~HHHHHHHTTS~SEEEEEEE~~HHHHTTSEE~S~SEEE~EEEEEESS~S~~SHHHHHH~SSSEEEEBTTSHHHHHHHH~~SHHHHHHHHHHHHHHHTT~BSSHHHHHHHHHHSSEEEEEEHHHHHHHHHH~TTEEEES~~S~~EEEEEEE~TT~THHHHHHHHHHHHHHTTHHHHHHHHHH~~~~~

G A N R T L I V T T I L E E P Y V M Y R K S D K P L Y G N D R F E G Y C L D L L K E L S N I L G F L Y D V K L V P D G K Y G A Q N D K G E W N G M V K E L I D H R A D L A V A P L T I T Y V R E K V I D F S K P F M T L G I S I L Y R K G T P I D S A D D L A K Q T K I E Y G A V R D G S T M T F F K K S K I S T Y E K M W A F M S S R Q Q S A L V K N S D E G I Q R V L T T D Y A L L M E S T S I E Y V T Q R N C N L T Q I G G L I D S K G Y G V G T P I G S P Y R D K I T I A I L Q L Q E E G K L H M M K E K W W G A N R T L I V T T I L E E P Y V M Y R K S D K P L Y G N D R F E G Y C L D L L K E L S N I L G F L Y D V K L V P D G K Y G A Q N D K G E W N G M V K E L I D H R A D L A V A P L T I T Y V R E K V I D F S K P F M T L G I S I L Y R K G T P I D S A D D L A K Q T K I E Y G A V R D G S T M T F F K K S K I S T Y E K M W A F M S S R Q Q S A L V K N S D E G I Q R V L T T D Y A L L M E S T S I E Y V T Q R N C N L T Q I G G L I D S K G Y G V G T P I G S P Y R D K I T I A I L Q L Q E E G K L H M M K E K W W R G N G C

AH

BS

1KG4

MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVARVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKP

~~HHHHHHHHHHHHHHH~~~~SGGGSS~~HHHHHHHHHHHTSS~HHHHHHHHHHHHHH~SSHHHHHHS~HHHHHHHHTTS~~THHHHHHHHHHHHHHHHSTTS~~~SHHHHHTSTT~~HHHHHHHHHHHH~~EE~~~~HHHHHHHHHHTT~~S~TTSHHHHHHHHHHHHHH~~STTHHHHHHHHHHHHHHTS~SSS~~GGG~TTTTT~HHHHHT~GGGSS~~~~

M Q A S Q F S A Q V L D W Y D K Y G R K T L P W Q I D K T P Y K V W L S E V M L Q Q T Q V A T V I P Y F E R F M A R F P T V T D L A N A P L D E V L H L W T G L G Y Y A R A R N L H K A A Q Q V A T L H G G K F P E T F E E V A A L P G V G R S T A G A I L S L S L G K H F P I L D G N V A R V L A R C Y A V S G W P G K K E V E N K L W S L S E Q V T P A V G V E R F N Q A M M D L G A M I C T R S K P K C S L C P L Q N G C I A A A N N S W A L Y P G K K P

AH

UNSTRUCTURED

3R4I

ALTPAEVLFDPAVLPACDHYAGSEKLLKSLALQQQLGPVFDITLDCEDGAQVGREAQHAELVASLLGSEHDRFGRVGVRIHDFDHAHWRDDVRLILRAAKRAPAYITLPKRHVHDAAEVAFIEATRRELGIAQPVPVQLLVETHGALTRVFDLAALPGVEALSFGLDFVSAHDGAIPDTARSPGQFDHPLVRRAKLEISAACHAYGKVPSHNVSTEVRDSVVANDAARARNEFGYTRWSIHPAQIEAIVAAFAPRDEEITTATEILLAAQSAQWGPTRYHDTLHDRASYRYYWSVLRRAQATGRAVPQDAAPLFALTPAEVLFDVLPACDHYAGSEKLLKSLALQQQLGPVFDITLDCEDGAQVGREAQHAELVASLLGSEHDRFGRVGVRIHDFDHAHWRDDVRLILRAAKRAPAYITLPKIRHVHDAAEVAFIEATRRELGIAQPVPVQLLVETHGALTRVFDLAALPGVEALSFGLDFVSAHDGAIPDTARSPGQFDHPLVRRAKLEISAACHAYGKVPSHNVSTEVRDSVVANDAARARNEFGYTRWSIHPAQIEAIVAAFAPRDEEITTATEILLAAQSAQWGPTRYHDTLHDRASYRYYWSVLRRAQATGRAVPQDAAPLFLTPAEVLFDPAVLPACDHYAGSEKLLKSLALQQQLGPVFDITLDCEDGAQVGREAQHAELVASLLGSEHDRFGRVGVRIHDFDHAHWRDDVRLILRAAKRAPAYITLPKIRHVHDAAEVAFIEATRRELGIAQPVPVQLLVETHGALTRVFDLAALPGVEALSFGLDFVSAHDGAIPDTARSPGQFDHPLVRRAKLEISAACHAYGKVPSHNVSTEVRDSVVANDAARARNEFGYTRWSIHPAQIEAIVAAFAPRDEEITTATEILLAAQSAQWGPTRYHDTLHDRASYRYYWSVLRRAQATGRAVPQDAAPLFLTPAEVLFDLPACDHYAGSEKLLKSLALQQQLGPVFDITLDCEDGAQVGREAQHAELVASLLGSEHDRFGRVGVRIHDFDHAHWRDDVRLILRAAKRAPAYITLPKIRHVHDAAEVAFIEATRRELGIAQPVPVQLLVETHGALTRVFDLAALPGVEALSFGLDFVSAHDGAIPDTARSPGQFDHPLVRRAKLEISAACHAYGKVPSHNVSTEVRDSVVANDAARARNEFGYTRWSIHPAQIEAIVAAFAPRDEEITTATEILLAAQSAQWGPTRYHDTLHDRASYRYYWSVLRRAQATGRAVPQDAAPLFRALTPAEVLFDLPACDHYAGSEKLLKSLALQQQLGPVFDITLDCEDGAQVGREAQHAELVASLLGSEHDRFGRVGVRIHDFDHAHWRDDVRLILRAAKRAPAYITLPKIRHVHDAAEVAFIEATRRELGIAQPVPVQLLVETHGALTRVFDLAALPGVEALSFGLDFVSAHDGAIPDTARSPGQFDHPLVRRAKLEISAACHAYGKVPSHNVSTEVRDSVVANDAARARNEFGYTRWSIHPAQIEAIVAAFAPRDEEITTATEILLAAQSAQWGPTRYHDTLHDRASYRYYWSVLRRAQATGRAVPQDAAPLFTLTPAEVLFDLPACDHYAGSEKLLKSLALQQQLGPVFDITLDCEDGAQVGREAQHAELVASLLGSEHDRFGRVGVRIHDFDHAHWRDDVRLILRAAKRAPAYITLPKIRHVHDAAEVAFIEATRRELGIAQPVPVQLLVETHGALTRVFDLAALPGVEALSFGLDFVSAHDGAIPDTARSPGQFDHPLVRRAKLEISAACHAYGKVPSHNVSTEVRDSVVANDAARARNEFGYTRWSIHPAQIEAIVAAFAPRDEEITTATEILLAAQSAQWGPTRYHDTLHDRASYRYYWSVLRRAQATGRAVPQDAAPLF

~~~HHHHS~~~~~~~SEEEEE~SS~~~HHHHHHHHH~TTEEEEEESSTTS~SS~HHHHHHHHHHHTTSSS~~SS~EEEE~~~TTSTTHHHHHHHHHHH~SS~~S~EEE~~~~HHHHH~~HHHHHHHHHTT~SS~~~EEEEE~SHHHHHTHHHHHT~TTEEEEEE~~~TTGGGTTSS~TT~~TTHHHHSHHHHHHHHHHHHHHHHTT~EEE~~~~~~S~~~HHHHHHHHHHHTT~~~~~BSSHHHHHHHHHHTS~~THHHHHHHHHHHHHHHTTTS~EEETTEEE~HHHHHHHHHHHHHHHHTT~~~~GGGGGG~~~~HHHHS~~~~~SEEEEE~SS~~~HHHHHHHHH~TTEEEEEESSTTS~SS~HHHHHHHHHHHTTSSS~~SS~EEEE~~~TTSTTHHHHHHHHHHH~SS~~S~EEE~~~~SHHHHH~~HHHHHHHHHTT~SS~~~EEEEE~SHHHHHTHHHHHT~TTEEEEEE~~~TTGGGTTSS~TT~~TTHHHHSHHHHHHHHHHHHHHHHTT~EEE~~~~~~S~~~HHHHHHHHHHHTT~~~~~BSSHHHHHHHHHHTS~~THHHHHHHHHHHHHHHTTTS~EEETTEEE~HHHHHHHHHHHHHHHHTT~~~~GGGGGG~~~HHHHS~~~~~~~SEEEEE~SS~~~HHHHHHHHH~SSEEEEEESSTTS~SS~HHHHHHHHHHHTTSSS~~SS~EEEE~~~TTSTTHHHHHHHHHHH~SS~~S~EEE~~~~SHHHHH~~HHHHHHHHHTT~SS~~~EEEEE~SHHHHHTHHHHHT~TTEEEEEE~~~TTGGGTTSS~TT~~TTHHHHSHHHHHHHHHHHHHHHHTT~EEE~~~~~~~~~~HHHHHHHHHHHTT~~~~~BSSHHHHHHHHHHTS~~THHHHHHHHHHHHHHHTTTS~EEETTEEE~HHHHHHHHHHHHHHHHTT~~~~GGGGGG~~~HHHHS~~~~SEEEEE~SS~~~HHHHHHHHH~SSEEEEEESSTTS~SS~HHHHHHHHHHHTTSTT~~SS~EEEE~~~TTSTTHHHHHHHHHHH~SS~~S~EEE~~~~SHHHHH~~HHHHHHHHHTT~SS~~~EEEEE~SHHHHHTHHHHHT~TTEEEEEE~~~TTGGGTTSS~TT~~TTHHHHSHHHHHHHHHHHHHHHHTT~EEE~~~~~~S~~~HHHHHHHHHHHTT~~~~~BSSHHHHHHHHHHTS~~THHHHHHHHHHHHHHHTTTS~EEETTEEE~HHHHHHHHHHHHHHHHTT~~~~GGGGGG~~~~~HHHHS~~~~SEEEEE~SS~~~HHHHHHHHH~SSEEEEEESSTTS~SS~HHHHHHHHHHHTTSSS~~SS~EEEE~~~TTSTTHHHHHHHHHHH~SS~~S~EEE~~~~SHHHHH~~HHHHHHHHHTT~SS~~~EEEEE~SHHHHHTHHHHHT~TTEEEEEE~~~TTGGGTTSS~TT~~TTHHHHSHHHHHHHHHHHHHHHHTT~EEE~~~~~~~~~~HHHHHHHHHHHTT~~~~~BSSHHHHHHHHHHTS~~THHHHHHHHHHHHHHHTTTS~EEETTEEE~HHHHHHHHHHHHHHHHTT~~~~GGGGGGT~~~HHHHS~~~~SEEEEE~SS~~~HHHHHHHHH~TTEEEEEESSTTS~SS~HHHHHHHHHHHTTSSS~~SS~EEEE~~~TTSTTHHHHHHHHHHH~SS~~S~EEE~~~~SHHHHH~~HHHHHHHHHTT~SS~~~EEEEE~SHHHHHTHHHHHT~TTEEEEEE~~~TTGGGTTSS~TT~~TTHHHHSHHHHHHHHHHHHHHHHTT~EEE~~~~~~~~~~HHHHHHHHHHHTT~~~~~BSSHHHHHHHHHHTS~~THHHHHHHHHHHHHHHTTT~~EEETTEEE~HHHHHHHHHHHHHHHHTT~~~~GGGGGG~

A L T P A E V L F D P A V L P A C D H Y A G S E K L L K S L A L Q Q Q L G P V F D I T L D C E D G A Q V G R E A Q H A E L V A S L L G S E H D R F G R V G V R I H D F D H A H W R D D V R L I L R A A K R A P A Y I T L P K R H V H D A A E V A F I E A T R R E L G I A Q P V P V Q L L V E T H G A L T R V F D L A A L P G V E A L S F G L D F V S A H D G A I P D T A R S P G Q F D H P L V R R A K L E I S A A C H A Y G K V P S H N V S T E V R D S V V A N D A A R A R N E F G Y T R W S I H P A Q I E A I V A A F A P R D E E I T T A T E I L L A A Q S A Q W G P T R Y H D T L H D R A S Y R Y Y W S V L R R A Q A T G R A V P Q D A A P L F A L T P A E V L F D V L P A C D H Y A G S E K L L K S L A L Q Q Q L G P V F D I T L D C E D G A Q V G R E A Q H A E L V A S L L G S E H D R F G R V G V R I H D F D H A H W R D D V R L I L R A A K R A P A Y I T L P K I R H V H D A A E V A F I E A T R R E L G I A Q P V P V Q L L V E T H G A L T R V F D L A A L P G V E A L S F G L D F V S A H D G A I P D T A R S P G Q F D H P L V R R A K L E I S A A C H A Y G K V P S H N V S T E V R D S V V A N D A A R A R N E F G Y T R W S I H P A Q I E A I V A A F A P R D E E I T T A T E I L L A A Q S A Q W G P T R Y H D T L H D R A S Y R Y Y W S V L R R A Q A T G R A V P Q D A A P L F L T P A E V L F D P A V L P A C D H Y A G S E K L L K S L A L Q Q Q L G P V F D I T L D C E D G A Q V G R E A Q H A E L V A S L L G S E H D R F G R V G V R I H D F D H A H W R D D V R L I L R A A K R A P A Y I T L P K I R H V H D A A E V A F I E A T R R E L G I A Q P V P V Q L L V E T H G A L T R V F D L A A L P G V E A L S F G L D F V S A H D G A I P D T A R S P G Q F D H P L V R R A K L E I S A A C H A Y G K V P S H N V S T E V R D S V V A N D A A R A R N E F G Y T R W S I H P A Q I E A I V A A F A P R D E E I T T A T E I L L A A Q S A Q W G P T R Y H D T L H D R A S Y R Y Y W S V L R R A Q A T G R A V P Q D A A P L F L T P A E V L F D L P A C D H Y A G S E K L L K S L A L Q Q Q L G P V F D I T L D C E D G A Q V G R E A Q H A E L V A S L L G S E H D R F G R V G V R I H D F D H A H W R D D V R L I L R A A K R A P A Y I T L P K I R H V H D A A E V A F I E A T R R E L G I A Q P V P V Q L L V E T H G A L T R V F D L A A L P G V E A L S F G L D F V S A H D G A I P D T A R S P G Q F D H P L V R R A K L E I S A A C H A Y G K V P S H N V S T E V R D S V V A N D A A R A R N E F G Y T R W S I H P A Q I E A I V A A F A P R D E E I T T A T E I L L A A Q S A Q W G P T R Y H D T L H D R A S Y R Y Y W S V L R R A Q A T G R A V P Q D A A P L F R A L T P A E V L F D L P A C D H Y A G S E K L L K S L A L Q Q Q L G P V F D I T L D C E D G A Q V G R E A Q H A E L V A S L L G S E H D R F G R V G V R I H D F D H A H W R D D V R L I L R A A K R A P A Y I T L P K I R H V H D A A E V A F I E A T R R E L G I A Q P V P V Q L L V E T H G A L T R V F D L A A L P G V E A L S F G L D F V S A H D G A I P D T A R S P G Q F D H P L V R R A K L E I S A A C H A Y G K V P S H N V S T E V R D S V V A N D A A R A R N E F G Y T R W S I H P A Q I E A I V A A F A P R D E E I T T A T E I L L A A Q S A Q W G P T R Y H D T L H D R A S Y R Y Y W S V L R R A Q A T G R A V P Q D A A P L F T L T P A E V L F D L P A C D H Y A G S E K L L K S L A L Q Q Q L G P V F D I T L D C E D G A Q V G R E A Q H A E L V A S L L G S E H D R F G R V G V R I H D F D H A H W R D D V R L I L R A A K R A P A Y I T L P K I R H V H D A A E V A F I E A T R R E L G I A Q P V P V Q L L V E T H G A L T R V F D L A A L P G V E A L S F G L D F V S A H D G A I P D T A R S P G Q F D H P L V R R A K L E I S A A C H A Y G K V P S H N V S T E V R D S V V A N D A A R A R N E F G Y T R W S I H P A Q I E A I V A A F A P R D E E I T T A T E I L L A A Q S A Q W G P T R Y H D T L H D R A S Y R Y Y W S V L R R A Q A T G R A V P Q D A A P L F

AH

UNSTRUCTURED

4CB8

MLDESSVKKMILTFEKRSYKNQELRIKFPDNPEKFMESELDLNDIIQEMHVVATMPDLYHLLVELNAVQSLLGLLGHDNTDVSIAVVDLLQELTDIDTLHESEEGAEVLIDALVDGQVVALLVQNLERLDESVKEEADGVHNTLAIVENMAEFRPEMCTEGAQQGLLQWLLKRLKAKMPFDANKLYCSEVLAILLQDNDENRELLGELDGIDVLLQQLSVFKRHNPSTAEEQEMMENLFDSLCSCLMLSSNRERFLKGEGLQLMNLMLREKKISRSSALKVLDHAMIGPEGTDNCHKFVDILGLRTIFPLFMKSPRKIKKVGTTEKEHEEHVCSILASLLRNLRGQQRTRLLNKFTENDSEKVDRLMELHFKYLGAMQVADKKIEGEKHDMVRRGEIIDNDTEEEFYLRRLDAGLFVLQHICYIMAEICNANVPQIRQRVHQILNMRGSSIKIVRHIIKEYAENIGDGRPEFRENEQKRILGLLENF

~~~HHHHHHHHHHHHHHHHHHHHHHHH~TT~HHHHHHHHHHHHHHHHHGGGGGG~GGGTHHHHHTTHHHHHHHHEE~SSHHHHHHHHHHHHHHH~HHHHHH~HHHHHHHHHHHHHHTHHHHHHHHHTT~~TTSHHHHHHHHHHHHHHHHHHHH~TTHHHHHHHTTHHHHHHHHHHSS~~~~HHHHHHHHHHHHHHTT~HHHHHHHHHTTHHHHHHHHHGGGSSS~~SSHHHHHHHHHHHHHHHHHHTSHHHHHHHHHTTHHHHHHHHHHHTSTTHHHHHHHHHHHHSSGGGHHHHHHHHHTTHHHHHHHHHHS~~TTHHHHS~~HHHHHHHHHHHHHHHHHH~~HHHHHHHHHHHHTTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT~~~~HHHHHHHHHHHHHHTHHHHHHHHHHHHHHTTS~~HHHHHHHHHHHHHTT~~HHHHHHHHHHHHHTTT~~~~HHHHHHHHHHHHTTTT~

M L D E S S V K K M I L T F E K R S Y K N Q E L R I K F P D N P E K F M E S E L D L N D I I Q E M H V V A T M P D L Y H L L V E L N A V Q S L L G L L G H D N T D V S I A V V D L L Q E L T D I D T L H E S E E G A E V L I D A L V D G Q V V A L L V Q N L E R L D E S V K E E A D G V H N T L A I V E N M A E F R P E M C T E G A Q Q G L L Q W L L K R L K A K M P F D A N K L Y C S E V L A I L L Q D N D E N R E L L G E L D G I D V L L Q Q L S V F K R H N P S T A E E Q E M M E N L F D S L C S C L M L S S N R E R F L K G E G L Q L M N L M L R E K K I S R S S A L K V L D H A M I G P E G T D N C H K F V D I L G L R T I F P L F M K S P R K I K K V G T T E K E H E E H V C S I L A S L L R N L R G Q Q R T R L L N K F T E N D S E K V D R L M E L H F K Y L G A M Q V A D K K I E G E K H D M V R R G E I I D N D T E E E F Y L R R L D A G L F V L Q H I C Y I M A E I C N A N V P Q I R Q R V H Q I L N M R G S S I K I V R H I I K E Y A E N I G D G R P E F R E N E Q K R I L G L L E N F

AH

T

3NJJ

GLAQFIKVNVTLENGEPVFIYTDANGQVCQGDITVTQAGTITYLLNDQTLKGLKFVGVGFVTPFDGIIDAVTISSDGMLVQLVDLDKTPGTTKFQFVLSNTANTLLVLSADPQIINRP

~~EEEEEEEEEEETTEEEEEEE~TTS~EE~~~EEESSSEEEEEEEEE~SSS~~EEEEEEESSTTSSS~~EEEE~TTSSEEEEEE~~~S~EEEEEEEEEE~SS~SS~EH~~~~EEEE~~

G L A Q F I K V N V T L E N G E P V F I Y T D A N G Q V C Q G D I T V T Q A G T I T Y L L N D Q T L K G L K F V G V G F V T P F D G I I D A V T I S S D G M L V Q L V D L D K T P G T T K F Q F V L S N T A N T L L V L S A D P Q I I N R P

BS

UNSTRUCTURED

5Q1A

MELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEAFSAEENFLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEARIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQKDHQLLRYLLDKMELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEAFSAEENFLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEARIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVHQLLRYLLDK

~~~~HHHHHHHHHHHHHHTTS~~HHHHHHHHHHS~~~HHHHHHHHHHHHHHHHHHHHHHHHHSTTGGGS~HHHHHHHHHHHHHHHHHHHHHHHHHS~~STTHHHHHHHHHHTSS~~HHHHHHHHHHHHHHHHTT~~HHHHHHHHHHHHT~TT~TT~S~HHHHHHHHHHHHHHHHHHHHHH~TT~TTHHHHHHHHHHHHTHHHHHHHHHHHTSS~S~~~~~HHHHHHHT~~~TTHHHHHHHH~~~~~HHHHHHHHHHHHHHTTS~~HHHHHHHHHH~~~~HHHHHHHHHHHHHHHHHHHHHHHHHSTEEEGS~HHHHHHHHHHHHHHHHHHHHHHHHHS~~STTHHHHHHHHHHTSSS~HHHHHHHHHHHHHHHHTT~~HHHHHHHHHHHHT~TT~TT~S~HHHHHHHHHHHHHHHHHHHHHH~TT~TTHHHHHHHHHHHHHHHHHTHHHHHHTSS~S~~~~~HHHHHHH~~~HHHHHHHH~

M E L T P D Q Q T L L H F I M D S Y N K Q R M P Q E I T N K I L K E A F S A E E N F L I L T E M A T N H V Q V L V E F T K K L P G F Q T L D H E D Q I A L L K G S A V E A M F L R S A E I F N K K L P S G H S D L L E A R I R N S G I S D E Y I T P M F S F Y K S I G E L K M T Q E E Y A L L T A I V I L S P D R Q Y I K D R E A V E K L Q E P L L D V L Q K L C K I H Q P E N P Q H F A C L L G R L T E L R T F N H H H A E M L M S W R V N D H K F T P L L C E I W D V Q K D H Q L L R Y L L D K M E L T P D Q Q T L L H F I M D S Y N K Q R M P Q E I T N K I L K E A F S A E E N F L I L T E M A T N H V Q V L V E F T K K L P G F Q T L D H E D Q I A L L K G S A V E A M F L R S A E I F N K K L P S G H S D L L E A R I R N S G I S D E Y I T P M F S F Y K S I G E L K M T Q E E Y A L L T A I V I L S P D R Q Y I K D R E A V E K L Q E P L L D V L Q K L C K I H Q P E N P Q H F A C L L G R L T E L R T F N H H H A E M L M S W R V N D H K F T P L L C E I W D V H Q L L R Y L L D K

AH

UNSTRUCTURED

4NXR

GAMGKVTHSIHIEKSDTAADTYGFSLSSVEEDGIRRLYVNSVKETGLASKKGLKAGDEILEINNRAADALNSSMMEDFFSQPSVGLLVRTYPELNKDKEYYV

~~~S~EEEEEEEEGGGSSSS~~S~EEEEEEETTEEEEEEE~~~TTSHHHHTT~~TT~EEEEETTEEGGG~~HHHHHHHHHSSEEEEEEEE~~~~~EEEEEE~

G A M G K V T H S I H I E K S D T A A D T Y G F S L S S V E E D G I R R L Y V N S V K E T G L A S K K G L K A G D E I L E I N N R A A D A L N S S M M E D F F S Q P S V G L L V R T Y P E L N K D K E Y Y V

BS

UNSTRUCTURED

4WGL

AAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANAAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDAGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANAAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDAGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANAAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDAGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANAAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDAGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANAAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDAGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANAAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDAGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANAAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDAGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANAAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDAGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANAAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDAGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANAAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDAGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANAAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDAGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANAAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDAGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANAAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDAGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANAAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDAGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLP

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HHHHHHHHHHHT~~~EETTTT~~GGG~~STTSEEEEEEEE~SS~EEEEEE~~~HHHHHHHHHHHHHHHHT~~SHHHHHHHHHHHHHHHH~EEEEEE~~SSHHHHHHHHHHHHHHHHHHHHHHHH~EEETTTHHHHHHHHTTTT~~~SSHHHHHHHHHHHHHTTHHHHHHHHHHTS~HHHHHHHHHTS~TTEEEETTTTEEEETTTTT~EEEHHHHHHHHHHHHHHHHHHHTEEEEEEE~~~~EEEEEHHHHHHHHHHHHHHHHHHHGGG~SSS~~EEEE~~SSSS~EEE~~HHHHHHH~~~SSHHHHHHHHHHHHHHHHHHHHHSS~HHHHHHHHHHHHHHHHHHHHTT~~HHHHHHHHHHHHHHHHHHHHHH~B~~~SHHHHHHHHHHHTTS~HHHHHHHHHHHHHH~TTSEEEEEE~SSSS~EEEEE~~EEE~~~BSSTT~~SBTTTTBEEEES~EEEEEESEE~~HHHHHHHHHHHHGGG~~EEEESSEE~HHHHHHHHHHHHTTSS~EEEE~~S~SHHHHHHHHHHHHHHHT~~~EETTTT~~GGG~~TTTSEE~SEEEE~SS~EEEE~~S~~SHHHHHHHHHHHHHHHS~SSHHHHHHHHHHHHHHHH~EEEEEE~~SSHHHHHHHHHHHHHHHHHHHHHHHH~EEETTTHHHHHHHHHTTT~~~SSHHHHHHHHHHHHHTTHHHHHHHHHHTS~HHHHHHHHHHS~TTEEEETTTTEEEETTTTT~EEEHHHHHHHHHHHHHHHHHHHTEEEEEEE~~~~EEEEEHHHHHHHHHHHHHHHHHHHGGG~STT~~EEEE~~SSSS~EEE~~HHHHHHH~~~SSHHHHHHHHHHHHHHHHHHHHHS~~HHHHHHHHHHHHHHHHHHHHTT~~HHHHHHHHHHHHHHHHHHHHHH~B~~~SHHHHHHHHHHHTTS~HHHHHHHHHHHHHH~TTSEEEEEE~SSSS~EEEEESEEEE~~~BSSS~S~SBTTTTBEEEES~EEEEEESEE~~HHHHHHHHHHHHHHT~~EEEEESEE~HHHHHHHHHHHHTTSS~EEEEE~SSSHHHHHHHHHHHHHHHT~~~EEGGGT~~STT~~GGG~EEEEEEEE~SS~EEEEEE~~~HHHHHHHHHHHHHHHHH~~SHHHHHHHHHHHHHHHH~EEEEEE~~SSHHHHHHHHHHHHHHHHHHHHHHHH~EEETTTHHHHHHHHHTTT~~~SSHHHHHHHHHHHHHTTHHHHHHHHHHTS~HHHHHHHHHHS~TTEEEETTTTEEEETTTTT~EEEHHHHHHHHHHHHHHHHHHHTEEEEEEE~~~~EEEEEHHHHHHHHHHHHHHHHHHHGGG~STT~~EEEE~~SSSS~EEE~~HHHHHHH~~~SSHHHHHHHHHHHHHHHHHHHHHSS~HHHHHHHHHHHHHHHHHHHHTT~~HHHHHHHHHHHHHHHHHHHHHH~B~~~SHHHHHHHHHHHTTS~HHHHHHHHHHHHHH~TT~EEEEEE~SSSS~EEEEESEEEES~~BSSSS~~SBTTTTBEEEES~EEEEEESEE~~TTTTHHHHHHHTTTT~~EEEEESEE~HHHHHHHHHHHHTTSS~EEEEE~SS~HHHHHHHHHHHHHHHT~~~EETTTT~~GGG~~TTTSEEEEEEEE~SS~EEEEEE~S~HHHHHHHHHHHHHHHHS~~SHHHHHHHHHHHHHHHH~EEEEEE~~SSHHHHHHHHHHHHHHHHHHHHHHHH~EEETTTHHHHHHHHHTTT~~~SSHHHHHHHHHHHHHTTHHHHHHHHHTTS~HHHHHHHHHHS~TTEEEETTTTEEEETTTTT~EEEHHHHHHHHHHHHHHHHHHHTEEEEEEE~~~~EEEEEHHHHHHHHHHHHHHHHHHHGGG~STT~~EEEE~~SSSS~EEE~~HHHHHHH~~~SSHHHHHHHHHHHHHHHHHHHHHSS~HHHHHHHHHHHHHHHHHHHHTT~~HHHHHHHHHHHHHHHHHHHHHH~B~~~SHHHHHHHHHHHTTS~HHHHHHHHHHHHHH~SSS~EEEEE~SSSS~EEEEESEEEE~~~~SSTT~~SBTTTTBEEEES~EEEEEEEEE~~TTTTHHHHHHHHHHT~~EEEEEEEE~THHHHHHHHHHHHTSS~EEEEE~SSSHHHHHHHHHHHHHHHT~~~EETTTT~~STT~~SSSSEEEEEEEE~SS~EEEEEE~~~HHHHHHHHHHHHHHHHT~SSHHHHHHHHHHHHHHHH~EEEEEE~~SSHHHHHHHHHHHHHHHHHHHHHHHH~EEETTTHHHHHHHHHTTT~~~SSHHHHHHHHHHHHHTTHHHHHHHHHTTS~HHHHHHHHHHS~TTEEEETTTTEEEETTTTT~EEEHHHHHHHHHHHHHHHHHHHTEEEEEEE~~

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G A A T E V E M K E K K A R V E D A L H A T R A A V E E G V V A G G G V A L I R V A S K L A D L R G Q N E D Q N V G I K V A L R A M E A P L R Q I V L N C G E E P S V V A N T V K G G D G N Y G Y N A A T E E Y G N M I D M G I L D P T K V T R S A L Q Y A A S V A G L M I T T E C M V T D L P A A K D V K F G N D A R V K M L R G V N V L A D A V K V T L G P K G R N V V L D K S F G A P T I T K D G V S V A R E I E L E D K F E N M G A Q M V K E V A S K A N A A A G D G T T T A T V L A Q A I I T E G L K A V A A G M N P M D L K R G I D K A V T A A V E E L K A L S V P C S D S K A I A Q V G T I S A N S D E T V G K L I A E A M D K V G K E G V I T V E D G T G L Q D E L D V V E G M Q F D A G Y L S P Y F I N K P E T G A V E L E S P F I L L A D K K I S N I R E M L P V L E A V A K A G K P L L I I A E D V E G E A L A T L V V N T M R G I V K V A A V K A P G F G D R R K A M L Q D I A T L T G G T V I S E E I G M E L E K A T L E D L G Q A K R V V I N K D T T T I I D G V G E E A A I Q G R V A Q I R Q Q I E E A T S D Y D R E K L Q E R V A K L A G G V A V I K V G A A T E V E M K E K K A R V E D A L H A T R A A V E E G V V A G G G V A L I R V A S K L A D L R G Q N E D Q N V G I K V A L R A M E A P L R Q I V L N C G E E P S V V A N T V K G G D G N Y G Y N A A T E E Y G N M I D M G I L D P T K V T R S A L Q Y A A S V A G L M I T T E C M V T D L P A A K D V K F G N D A R V K M L R G V N V L A D A V K V T L G P K G R N V V L D K S F G A P T I T K D G V S V A R E I E L E D K F E N M G A Q M V K E V A S K A N A A A G D G T T T A T V L A Q A I I T E G L K A V A A G M N P M D L K R G I D K A V T A A V E E L K A L S V P C S D S K A I A Q V G T I S A N S D E T V G K L I A E A M D K V G K E G V I T V E D G T G L Q D E L D V V E G M Q F D A G Y L S P Y F I N K P E T G A V E L E S P F I L L A D K K I S N I R E M L P V L E A V A K A G K P L L I I A E D V E G E A L A T L V V N T M R G I V K V A A V K A P G F G D R R K A M L Q D I A T L T G G T V I S E E I G M E L E K A T L E D L G Q A K R V V I N K D T T T I I D G V G E E A A I Q G R V A Q I R Q Q I E E A T S D Y D R E K L Q E R V A K L A G G V A V I K V G A A T E V E M K E K K A R V E D A L H A T R A A V E E G V V A G G G V A L I R V A S K L A D L R G Q N E D Q N V G I K V A L R A M E A P L R Q I V L N C G E E P S V V A N T V K G G D G N Y G Y N A A T E E Y G N M I D M G I L D P T K V T R S A L Q Y A A S V A G L M I T T E C M V T D L P A A K D V K F G N D A R V K M L R G V N V L A D A V K V T L G P K G R N V V L D K S F G A P T I T K D G V S V A R E I E L E D K F E N M G A Q M V K E V A S K A N A A A G D G T T T A T V L A Q A I I T E G L K A V A A G M N P M D L K R G I D K A V T A A V E E L K A L S V P C S D S K A I A Q V G T I S A N S D E T V G K L I A E A M D K V G K E G V I T V E D G T G L Q D E L D V V E G M Q F D A G Y L S P Y F I N K P E T G A V E L E S P F I L L A D K K I S N I R E M L P V L E A V A K A G K P L L I I A E D V E G E A L A T L V V N T M R G I V K V A A V K A P G F G D R R K A M L Q D I A T L T G G T V I S E E I G M E L E K A T L E D L G Q A K R V V I N K D T T T I I D G V G E E A A I Q G R V A Q I R Q Q I E E A T S D Y D R E K L Q E R V A K L A G G V A V I K V G A A T E V E M K E K K A R V E D A L H A T R A A V E E G V V A G G G V A L I R V A S K L A D L R G Q N E D Q N V G I K V A L R A M E A P L R Q I V L N C G E E P S V V A N T V K G G D G N Y G Y N A A T E E Y G N M I D M G I L D P T K V T R S A L Q Y A A S V A G L M I T T E C M V T D L P A A K D V K F G N D A R V K M L R G V N V L A D A V K V T L G P K G R N V V L D K S F G A P T I T K D G V S V A R E I E L E D K F E N M G A Q M V K E V A S K A N A A A G D G T T T A T V L A Q A I I T E G L K A V A A G M N P M D L K R G I D K A V T A A V E E L K A L S V P C S D S K A I A Q V G T I S A N S D E T V G K L I A E A M D K V G K E G V I T V E D G T G L Q D E L D V V E G M Q F D A G Y L S P Y F I N K P E T G A V E L E S P F I L L A D K K I S N I R E M L P V L E A V A K A G K P L L I I A E D V E G E A L A T L V V N T M R G I V K V A A V K A P G F G D R R K A M L Q D I A T L T G G T V I S E E I G M E L E K A T L E D L G Q A K R V V I N K D T T T I I D G V G E E A A I Q G R V A Q I R Q Q I E E A T S D Y D R E K L Q E R V A K L A G G V A V I K V G A A T E V E M K E K K A R V E D A L H A T R A A V E E G V V A G G G V A L I R V A S K L A D L R G Q N E D Q N V G I K V A L R A M E A P L R Q I V L N C G E E P S V V A N T V K G G D G N Y G Y N A A T E E Y G N M I D M G I L D P T K V T R S A L Q Y A A S V A G L M I T T E C M V T D L P A A K D V K F G N D A R V K M L R G V N V L A D A V K V T L G P K G R N V V L D K S F G A P T I T K D G V S V A R E I E L E D K F E N M G A Q M V K E V A S K A N A A A G D G T T T A T V L A Q A I I T E G L K A V A A G M N P M D L K R G I D K A V T A A V E E L K A L S V P C S D S K A I A Q V G T I S A N S D E T V G K L I A E A M D K V G K E G V I T V E D G T G L Q D E L D V V E G M Q F D A G Y L S P Y F I N K P E T G A V E L E S P F I L L A D K K I S N I R E M L P V L E A V A K A G K P L L I I A E D V E G E A L A T L V V N T M R G I V K V A A V K A P G F G D R R K A M L Q D I A T L T G G T V I S E E I G M E L E K A T L E D L G Q A K R V V I N K D T T T I I D G V G E E A A I Q G R V A Q I R Q Q I E E A T S D Y D R E K L Q E R V A K L A G G V A V I K V G A A T E V E M K E K K A R V E D A L H A T R A A V E E G V V A G G G V A L I R V A S K L A D L R G Q N E D Q N V G I K V A L R A M E A P L R Q I V L N C G E E P S V V A N T V K G G D G N Y G Y N A A T E E Y G N M I D M G I L D P T K V T R S A L Q Y A A S V A G L M I T T E C M V T D L P A A K D V K F G N D A R V K M L R G V N V L A D A V K V T L G P K G R N V V L D K S F G A P T I T K D G V S V A R E I E L E D K F E N M G A Q M V K E V A S K A N A A A G D G T T T A T V L A Q A I I T E G L K A V A A G M N P M D L K R G I D K A V T A A V E E L K A L S V P C S D S K A I A Q V G T I S A N S D E T V G K L I A E A M D K V G K E G V I T V E D G T G L Q D E L D V V E G M Q F D A G Y L S P Y F I N K P E T G A V E L E S P F I L L A D K K I S N I R E M L P V L E A V A K A G K P L L I I A E D V E G E A L A T L V V N T M R G I V K V A A V K A P G F G D R R K A M L Q D I A T L T G G T V I S E E I G M E L E K A T L E D L G Q A K R V V I N K D T T T I I D G V G E E A A I Q G R V A Q I R Q Q I E E A T S D Y D R E K L Q E R V A K L A G G V A V I K V G A A T E V E M K E K K A R V E D A L H A T R A A V E E G V V A G G G V A L I R V A S K L A D L R G Q N E D Q N V G I K V A L R A M E A P L R Q I V L N C G E E P S V V A N T V K G G D G N Y G Y N A A T E E Y G N M I D M G I L D P T K V T R S A L Q Y A A S V A G L M I T T E C M V T D L P A A K D V K F G N D A R V K M L R G V N V L A D A V K V T L G P K G R N V V L D K S F G A P T I T K D G V S V A R E I E L E D K F E N M G A Q M V K E V A S K A N A A A G D G T T T A T V L A Q A I I T E G L K A V A A G M N P M D L K R G I D K A V T A A V E E L K A L S V P C S D S K A I A Q V G T I S A N S D E T V G K L I A E A M D K V G K E G V I T V E D G T G L Q D E L D V V E G M Q F D A G Y L S P Y F I N K P E T G A V E L E S P F I L L A D K K I S N I R E M L P V L E A V A K A G K P L L I I A E D V E G E A L A T L V V N T M R G I V K V A A V K A P G F G D R R K A M L Q D I A T L T G G T V I S E E I G M E L E K A T L E D L G Q A K R V V I N K D T T T I I D G V G E E A A I Q G R V A Q I R Q Q I E E A T S D Y D R E K L Q E R V A K L A G G V A V I K V G A A T E V E M K E K K A R V E D A L H A T R A A V E E G V V A G G G V A L I R V A S K L A D L R G Q N E D Q N V G I K V A L R A M E A P L R Q I V L N C G E E P S V V A N T V K G G D G N Y G Y N A A T E E Y G N M I D M G I L D P T K V T R S A L Q Y A A S V A G L M I T T E C M V T D L P A A K D V K F G N D A R V K M L R G V N V L A D A V K V T L G P K G R N V V L D K S F G A P T I T K D G V S V A R E I E L E D K F E N M G A Q M V K E V A S K A N A A A G D G T T T A T V L A Q A I I T E G L K A V A A G M N P M D L K R G I D K A V T A A V E E L K A L S V P C S D S K A I A Q V G T I S A N S D E T V G K L I A E A M D K V G K E G V I T V E D G T G L Q D E L D V V E G M Q F D A G Y L S P Y F I N K P E T G A V E L E S P F I L L A D K K I S N I R E M L P V L E A V A K A G K P L L I I A E D V E G E A L A T L V V N T M R G I V K V A A V K A P G F G D R R K A M L Q D I A T L T G G T V I S E E I G M E L E K A T L E D L G Q A K R V V I N K D T T T I I D G V G E E A A I Q G R V A Q I R Q Q I E E A T S D Y D R E K L Q E R V A K L A G G V A V I K V G A A T E V E M K E K K A R V E D A L H A T R A A V E E G V V A G G G V A L I R V A S K L A D L R G Q N E D Q N V G I K V A L R A M E A P L R Q I V L N C G E E P S V V A N T V K G G D G N Y G Y N A A T E E Y G N M I D M G I L D P T K V T R S A L Q Y A A S V A G L M I T T E C M V T D L P

AH

BS

2BYJ

GPPTSDDIFEREYKYGAHNYHPLPVALERGKGIYLWDVEGRKYFDFLSSISAVNQGHCHPKIVNALKSQVDKLTLTSRAFYNNVLGEYEEYITKLFNYHKVLPMNTGVEAGETACKLARKWGYTVKGIQKYKAKIVFAAGNFWGRTLSAISSSTDPTSYDGFGPFMPGFDIIPYNDLPALERALQDPNVAAFMVEPIQGEAGVVVPDPGYLMGVRELCTRHQVLFIADEIQTGLARTGRWLAVDYENVRPDIVLLGKALSGGLYPVSAVLCDDDIMLTIKPGEHGSTYGGNPLGCRVAIAALEVLEEENLAENADKLGIILRNELMKLPSDVVTAVRGKGLLNAIVIKETKDWDAWKVCLRLRDNGLLAKPTHGDIIRFAPPLVIKEDELRESIEIINKTILSFGPPTSDDIFEREYKYGAHNYHPLPVALERGKGIYLWDVEGRKYFDFLSSISAVNQGHCHPKIVNALKSQVDKLTLTSRAFYNNVLGEYEEYITKLFNYHKVLPMNTGVEAGETACKLARKWGYTVKGIQKYKAKIVFAAGNFWGRTLSAISSSTDPTSYDGFGPFMPGFDIIPYNDLPALERALQDPNVAAFMVEPIQGEAGVVVPDPGYLMGVRELCTRHQVLFIADEIQTGLARTGRWLAVDYENVRPDIVLLGKALSGGLYPVSAVLCDDDIMLTIKPGEHGSTYGGNPLGCRVAIAALEVLEEENLAENADKLGIILRNELMKLPSDVVTAVRGKGLLNAIVIKETKDWDAWKVCLRLRDNGLLAKPTHGDIIRFAPPLVIKEDELRESIEIINKTILSFGPPTSDDIFEREYKYGAHNYHPLPVALERGKGIYLWDVEGRKYFDFLSSISAVNQGHCHPKIVNALKSQVDKLTLTSRAFYNNVLGEYEEYITKLFNYHKVLPMNTGVEAGETACKLARKWGYTVKGIQKYKAKIVFAAGNFWGRTLSAISSSTDPTSYDGFGPFMPGFDIIPYNDLPALERALQDPNVAAFMVEPIQGEAGVVVPDPGYLMGVRELCTRHQVLFIADEIQTGLARTGRWLAVDYENVRPDIVLLGKALSGGLYPVSAVLCDDDIMLTIKPGEHGSTYGGNPLGCRVAIAALEVLEEENLAENADKLGIILRNELMKLPSDVVTAVRGKGLLNAIVIKETKDWDAWKVCLRLRDNGLLAKPTHGDIIRFAPPLVIKEDELRESIEIINKTILSF

~~~~HHHHHHHHHHHB~~~~~~EEEEEEEEEBTEEEETT~~EEEESSHHHHTTTT~BT~HHHHHHHHHHHTT~S~~~TTEEETTHHHHHHHHHHHHT~SEEEEESSHHHHHHHHHHHHHHHHHHTT~~~TT~~EEEEETT~~~~SSHHHHHT~~~HHHHTTS~S~~TTEEEE~TT~HHHHHHHTTSTTEEEEEE~SSBTTTTSB~~~TTHHHHHHHHHHHTT~EEEEE~TTTTTTTTSSSSGGGGGT~~~SEEEE~GGGGTTSS~~EEEEE~HHHHTTS~TTSS~~SSTT~HHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHTTS~TTTEEEEEEETTEEEEEE~~~SS~~HHHHHHHHHHTTEE~EEEETTEEEE~~~TT~~HHHHHHHHHHHHHHHHT~~~~~HHHHHHHHHHHB~~~~~~EEEEEEEEEBTEEEETT~~EEEESSHHHHTTTT~BT~HHHHHHHHHHHTT~S~~~TTEEETTHHHHHHHHHHHHT~SEEEEESSHHHHHHHHHHHHHHHHHHTT~~~TT~~EEEEETT~~~~SSHHHHHT~~~HHHHTTS~S~~TTEEEE~TT~HHHHHHHTTSTTEEEEEE~SSBTTTTSB~~~TTHHHHHHHHHHHTT~EEEEE~TTTTTTTTSSSSGGGGGT~~~SEEEE~GGGGTTSS~~EEEEE~HHHHTTS~TTSS~~SSTT~HHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHTTS~TTTEEEEEEETTEEEEEE~~~SS~~HHHHHHHHHHTTEE~EEEETTEEEE~~~TT~~HHHHHHHHHHHHHHHHT~~~~~HHHHHHHHHHHS~~~~~~~S~~EEEEEBTEEEETT~~EEEESSHHHHTTTT~BT~HHHHHHHHHHHTT~S~~~TTS~~TTHHHHHHHHHHHHT~SEEEEESSHHHHHHHHHHHHHHHHHHTT~~~TT~~EEEEETT~~~~SSHHHHHT~~~HHHHTTS~S~~TTEEEE~TT~HHHHHHHTTSTTEEEEEE~SSBTTTTSB~~~TTHHHHHHHHHHHTT~EEEEE~TTTTTTTTSSSSGGGGGT~~~SEEEE~GGGGTTSS~~EEEEE~HHHHTTS~TTSS~~SSTT~HHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHTTS~TTTEEEEEEETTEEEEEE~~~SS~~HHHHHHHHHHTTEE~EEEETTEEEE~~~TT~~HHHHHHHHHHHHHHHHT~

G P P T S D D I F E R E Y K Y G A H N Y H P L P V A L E R G K G I Y L W D V E G R K Y F D F L S S I S A V N Q G H C H P K I V N A L K S Q V D K L T L T S R A F Y N N V L G E Y E E Y I T K L F N Y H K V L P M N T G V E A G E T A C K L A R K W G Y T V K G I Q K Y K A K I V F A A G N F W G R T L S A I S S S T D P T S Y D G F G P F M P G F D I I P Y N D L P A L E R A L Q D P N V A A F M V E P I Q G E A G V V V P D P G Y L M G V R E L C T R H Q V L F I A D E I Q T G L A R T G R W L A V D Y E N V R P D I V L L G K A L S G G L Y P V S A V L C D D D I M L T I K P G E H G S T Y G G N P L G C R V A I A A L E V L E E E N L A E N A D K L G I I L R N E L M K L P S D V V T A V R G K G L L N A I V I K E T K D W D A W K V C L R L R D N G L L A K P T H G D I I R F A P P L V I K E D E L R E S I E I I N K T I L S F G P P T S D D I F E R E Y K Y G A H N Y H P L P V A L E R G K G I Y L W D V E G R K Y F D F L S S I S A V N Q G H C H P K I V N A L K S Q V D K L T L T S R A F Y N N V L G E Y E E Y I T K L F N Y H K V L P M N T G V E A G E T A C K L A R K W G Y T V K G I Q K Y K A K I V F A A G N F W G R T L S A I S S S T D P T S Y D G F G P F M P G F D I I P Y N D L P A L E R A L Q D P N V A A F M V E P I Q G E A G V V V P D P G Y L M G V R E L C T R H Q V L F I A D E I Q T G L A R T G R W L A V D Y E N V R P D I V L L G K A L S G G L Y P V S A V L C D D D I M L T I K P G E H G S T Y G G N P L G C R V A I A A L E V L E E E N L A E N A D K L G I I L R N E L M K L P S D V V T A V R G K G L L N A I V I K E T K D W D A W K V C L R L R D N G L L A K P T H G D I I R F A P P L V I K E D E L R E S I E I I N K T I L S F G P P T S D D I F E R E Y K Y G A H N Y H P L P V A L E R G K G I Y L W D V E G R K Y F D F L S S I S A V N Q G H C H P K I V N A L K S Q V D K L T L T S R A F Y N N V L G E Y E E Y I T K L F N Y H K V L P M N T G V E A G E T A C K L A R K W G Y T V K G I Q K Y K A K I V F A A G N F W G R T L S A I S S S T D P T S Y D G F G P F M P G F D I I P Y N D L P A L E R A L Q D P N V A A F M V E P I Q G E A G V V V P D P G Y L M G V R E L C T R H Q V L F I A D E I Q T G L A R T G R W L A V D Y E N V R P D I V L L G K A L S G G L Y P V S A V L C D D D I M L T I K P G E H G S T Y G G N P L G C R V A I A A L E V L E E E N L A E N A D K L G I I L R N E L M K L P S D V V T A V R G K G L L N A I V I K E T K D W D A W K V C L R L R D N G L L A K P T H G D I I R F A P P L V I K E D E L R E S I E I I N K T I L S F

AH

BS

3L9N

SVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYAPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLMIDQQGYIKVTDFGFAKRVKGRTWLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPGPGDTSNFDDYEEEEIRVINEKCGKEFSEFTTYADFIASGRTGRRNAIH

~HHHHHHHHHHHHHHHHH~~~~~~~~GGGEEEEEEEEEETTEEEEEEEETTT~~EEEEEEEEHHHHHHTT~HHHHHHHHHHHHH~~~TTB~~EEEEEE~SSEEEEEE~~~TTEEHHHHHHHH~S~~HHHHHHHHHHHHHHHHHHHHTTEE~~~~SGGGEEE~TTS~EEE~~~SS~EE~SS~B~~~S~GGG~~HHHHTT~~B~THHHHHHHHHHHHHHHHSS~SS~~SSHHHHHHHHHHT~~~~~TTS~HHHHHHHHHHS~S~TTTSTTSSTTTTHHHHTSGGGTT~~HHHHHTT~S~~S~~~~TT~~TTS~~~~~~~~~~~~~~STTTTTT~~HHHHHHHHT~~S~~~~~~

S V K E F L A K A K E D F L K K W E S P A Q N T A H L D Q F E R I K T L G T G S F G R V M L V K H K E T G N H Y A M K I L D K Q K V V K L K Q I E H T L N E K R I L Q A V N F P F L V K L E F S F K D N S N L Y M V M E Y A P G G E M F S H L R R I G R F S E P H A R F Y A A Q I V L T F E Y L H S L D L I Y R D L K P E N L M I D Q Q G Y I K V T D F G F A K R V K G R T W L C G T P E Y L A P E I I L S K G Y N K A V D W W A L G V L I Y E M A A G Y P P F F A D Q P I Q I Y E K I V S G K V R F P S H F S S D L K D L L R N L L Q V D L T K R F G N L K N G V N D I K N H K W F A T T D W I A I Y Q R K V E A P F I P G P G D T S N F D D Y E E E E I R V I N E K C G K E F S E F T T Y A D F I A S G R T G R R N A I H

AH

UNSTRUCTURED

5F7A

ATAAEIAALPRQKVELVDPPFVHAHSQVAEGGPKVVEFTMVIEEKKIVIDDAGTEVHAMAFNGTVPGPLMVVHQDDYLELTLINPETNTLMHNIDFHAATGALGGGGLTEINPGEKTILRFKATKPGVFVYHCAPPGMVPWHVVSGMNGAIMVLPREGLHDGKGKALTYDKIYYVGEQDFYVPRDENGKYKKYEAPGDAYEDTVKVMRTLTPTHVVFNGAVGALTGDKAMTAAVGEKVLIVHSQANRDTRPHLIGGHGDYVWATGKFNTPPDVDQETWFIPGGAAGAAFYTFQQPGIYAYVNHNLIEAFELGAAAHFKVTGEWNDDLMTSVLAPSGATAAEIAALPRQKVELVDPPFVHAHSQVAEGGPKVVEFTMVIEEKKIVIDDAGTEVHAMAFNGTVPGPLMVVHQDDYLELTLINPETNTLMHNIDFHAATGALGGGGLTEINPGEKTILRFKATKPGVFVYHCAPPGMVPWHVVSGMNGAIMVLPREGLHDGKGKALTYDKIYYVGEQDFYVPRDENGKYKKYEAPGDAYEDTVKVMRTLTPTHVVFNGAVGALTGDKAMTAAVGEKVLIVHSQANRDTRPHLIGGHGDYVWATGKFNTPPDVDQETWFIPGGAAGAAFYTFQQPGIYAYVNHNLIEAFELGAAAHFKVTGEWNDDLMTSVLAPSGTATAAEIAALPRQKVELVDPPFVHAHSQVAEGGPKVVEFTMVIEEKKIVIDDAGTEVHAMAFNGTVPGPLMVVHQDDYLELTLINPETNTLMHNIDFHAATGALGGGGLTEINPGEKTILRFKATKPGVFVYHCAPPGMVPWHVVSGMNGAIMVLPREGLHDGKGKALTYDKIYYVGEQDFYVPRDENGKYKKYEAPGDAYEDTVKVMRTLTPTHVVFNGAVGALTGDKAMTAAVGEKVLIVHSQANRDTRPHLIGGHGDYVWATGKFNTPPDVDQETWFIPGGAAGAAFYTFQQPGIYAYVNHNLIEAFELGAAAHFKVTGEWNDDLMTSVLAPSG

~~HHHHHTS~EEE~~~~~TTS~~~~~SS~~SS~~EEEEEEEEEEEEEE~STT~~EEEEEEETTSSS~~~EEEETT~EEEEEEEE~TT~~S~B~~EETTS~SGGGGGGG~~B~TTEEEEEEEE~~S~EEEEEE~~~TT~HHHHHHTT~EEEEEEE~TT~~B~TTS~B~~~SEEEEEEEEEE~~~B~TTS~B~~~SSGGGGHHHHHHHHTTT~~SEEEETTSTTTTSGGG~EEEETT~EEEEEEEESSS~B~EEEET~~EEEEETT~BTTS~~EEEESS~~B~TTEEEEEEEE~~S~EEEEEEESSHHHHHTSS~EEEEEEES~~~TTTEEEEEEEE~~~HHHHHTS~EEE~~~~~TTS~~~~~SS~~SS~~EEEEEEEEEEEEEE~STT~~EEEEEEETTSSS~~~EEEETT~EEEEEEEE~TT~~S~B~~EETTS~SGGGGGGG~~B~TTEEEEEEEE~~S~EEEEEE~~~TT~HHHHHHTT~EEEEEEE~TT~EE~TTS~EE~~SEEEEEEEEEE~~~B~TTS~B~~~SSHHHHHHHHHHHHTTT~~SEEEETTSTTTTSGGG~EEEETT~EEEEEEEESSS~B~EEEET~~EEEEETT~BTTS~~EEEESS~~B~TTEEEEEEEE~~S~EEEEEEESSHHHHHTSS~EEEEEEES~~~TTTEEEEEEEEE~~~HHHHHTS~EEE~~~~~TTS~~~~~SS~~SS~~EEEEEEEEEEEEEE~STT~~EEEEEEETTSSS~~~EEEETT~EEEEEEEE~TT~~S~B~~EETTS~SGGGGGGG~~B~TTEEEEEEEE~~S~EEEEEE~~~TT~HHHHHHTT~EEEEEEE~TT~EE~TTS~EE~~SEEEEEEEEEE~~~B~TTS~B~~~SSGGGGHHHHHHHHTTT~~SEEEETTBTTTTSGGG~EEEETT~EEEEEEEESSS~B~EEEET~~EEEEETT~BTTS~~EEEESS~~B~TTEEEEEEEE~~S~EEEEEEESSHHHHHTTS~EEEEEEES~~~TTTEEEEEEEE~

A T A A E I A A L P R Q K V E L V D P P F V H A H S Q V A E G G P K V V E F T M V I E E K K I V I D D A G T E V H A M A F N G T V P G P L M V V H Q D D Y L E L T L I N P E T N T L M H N I D F H A A T G A L G G G G L T E I N P G E K T I L R F K A T K P G V F V Y H C A P P G M V P W H V V S G M N G A I M V L P R E G L H D G K G K A L T Y D K I Y Y V G E Q D F Y V P R D E N G K Y K K Y E A P G D A Y E D T V K V M R T L T P T H V V F N G A V G A L T G D K A M T A A V G E K V L I V H S Q A N R D T R P H L I G G H G D Y V W A T G K F N T P P D V D Q E T W F I P G G A A G A A F Y T F Q Q P G I Y A Y V N H N L I E A F E L G A A A H F K V T G E W N D D L M T S V L A P S G A T A A E I A A L P R Q K V E L V D P P F V H A H S Q V A E G G P K V V E F T M V I E E K K I V I D D A G T E V H A M A F N G T V P G P L M V V H Q D D Y L E L T L I N P E T N T L M H N I D F H A A T G A L G G G G L T E I N P G E K T I L R F K A T K P G V F V Y H C A P P G M V P W H V V S G M N G A I M V L P R E G L H D G K G K A L T Y D K I Y Y V G E Q D F Y V P R D E N G K Y K K Y E A P G D A Y E D T V K V M R T L T P T H V V F N G A V G A L T G D K A M T A A V G E K V L I V H S Q A N R D T R P H L I G G H G D Y V W A T G K F N T P P D V D Q E T W F I P G G A A G A A F Y T F Q Q P G I Y A Y V N H N L I E A F E L G A A A H F K V T G E W N D D L M T S V L A P S G T A T A A E I A A L P R Q K V E L V D P P F V H A H S Q V A E G G P K V V E F T M V I E E K K I V I D D A G T E V H A M A F N G T V P G P L M V V H Q D D Y L E L T L I N P E T N T L M H N I D F H A A T G A L G G G G L T E I N P G E K T I L R F K A T K P G V F V Y H C A P P G M V P W H V V S G M N G A I M V L P R E G L H D G K G K A L T Y D K I Y Y V G E Q D F Y V P R D E N G K Y K K Y E A P G D A Y E D T V K V M R T L T P T H V V F N G A V G A L T G D K A M T A A V G E K V L I V H S Q A N R D T R P H L I G G H G D Y V W A T G K F N T P P D V D Q E T W F I P G G A A G A A F Y T F Q Q P G I Y A Y V N H N L I E A F E L G A A A H F K V T G E W N D D L M T S V L A P S G

BS

UNSTRUCTURED

5DJQ

TSTAYSYKVVRQFAIMTVVWGIVGMGLGVFIAAQLAWPFLNFDLPWTSFGRLRPLHTNAVIFAFGGCALFATSYYSVQRTCQTTLFAPKLAAFTFWGWQLVILLAAISLPLGFTSSKEYAELEWPIDILITIVWVAYAVVFFGTLAKRKVKHIYVGNWFFGAFILTVAILHVVNNLEIPVTAMKSYSLYAGATDAMVQWWYGHNAVGFFLTAGFLGIMYYFVPKQAERPVYSYRLSIVHFWALITVYIWAGPHHLHYTALPDWAQSLGMVMSLILLAPSWGGMINGMMTLSGAWHKLRSDPILRFLVVSLAFYGMSTFEGPMMAIKTVNALSHYTDWTIGHVHAGALGWVAMVSIGALYHLVPKVFGREQMHSIGLINTHFWLATIGTVLYIASMWVNGIAQGLMWRAINDDGTLTYSFVESLEASHPGFVVRMIGGAIFFAGMLVMAYNTWRTVQAAKPAEYDAAKLEKNVGLLTLFMILAVSIGGLTQIVPLFFQDSVNEPVEGMKPYTALQLEGRDLYIREGCVGCHSQMIRPFRAETERYGHYSVAGESVYDHPFLWGSKRTGPDLARVGGRYSDDWHRAHLYNPRNVVPESKMPSYPWLVENTLDGKDTAKKMSALRMLGVPYTEEDIAGARDSVNGKTEMDAMVAYLQVLGTALTNKMSTFWSGYIALLTLGTIVALFWLIFATRKGESAGTTDQTMGHAFDGIEEYDNPLPRWWFLLFIGTLVFGILYLVLYPGLGNWKGVLPGYEGGWTQEKQWEREVAQADEKYGPIFAKYAAMSVEEVAQDPQAVKMGARLFANYCSICHGSDAKGSLGFPNLADQDWRWGGDAASIKTSILNGRIAAMPAWGQAIGEEGVKNVAAFVRKDLAGLPLPEGTDADLSAGKNVYAQTCAVCHGQGGEGMAALGAPKLNSAAGWIYGSSLGQLQQTIRHGRNGQMPAQQQYLGDDKVHLLAAYVYSLSQAYSYKVVRQFAIMTVVWGIVGMGLGVFIAAQLAWPFLNFDLPWTSFGRLRPLHTNAVIFAFGGCALFATSYYSVQRTCQTTLFAPKLAAFTFWGWQLVILLAAISLPLGFTSSKEYAELEWPIDILITIVWVAYAVVFFGTLAKRKVKHIYVGNWFFGAFILTVAILHVVNNLEIPVTAMKSYSLYAGATDAMVQWWYGHNAVGFFLTAGFLGIMYYFVPKQAERPVYSYRLSIVHFWALITVYIWAGPHHLHYTALPDWAQSLGMVMSLILLAPSWGGMINGMMTLSGAWHKLRSDPILRFLVVSLAFYGMSTFEGPMMAIKTVNALSHYTDWTIGHVHAGALGWVAMVSIGALYHLVPKVFGREQMHSIGLINTHFWLATIGTVLYIASMWVNGIAQGLMWRAINDDGTLTYSFVESLEASHPGFVVRMIGGAIFFAGMLVMAYNTWRTVQAAKPAEYDAAKLEKNVGLLTLFMILAVSIGGLTQIVPLFFQDSVNEPVEGMKPYTALQLEGRDLYIREGCVGCHSQMIRPFRAETERYGHYSVAGESVYDHPFLWGSKRTGPDLARVGGRYSDDWHRAHLYNPRNVVPESKMPSYPWLVENTLDGKDTAKKMSALRMLGVPYTEEDIAGARDSVNGKTEMDAMVAYLQVLGTALTNKMSTFWSGYIALLTLGTIVALFWLIFATRKGESAGTTDQTMGHAFDGIEEYDNPLPRWWFLLFIGTLVFGILYLVLYPGLGNWKGVLPGYEGGWTQEKQWEREVAQADEKYGPIFAKYAAMSVEEVAQDPQAVKMGARLFANYCSICHGSDAKGSLGFPNLADQDWRWGGDAASIKTSILNGRIAAMPAWGQAIGEEGVKNVAAFVRKDLAGLPLPEGTDADLSAGKNVYAQTCAVCHGQGGEGMAALGAPKLNSAAGWIYGSSLGQLQQTIRHGRNGQMPAQQQYLGDDKVHLLAAYVYSLSQSTAYSYKVVRQFAIMTVVWGIVGMGLGVFIAAQLAWPFLNFDLPWTSFGRLRPLHTNAVIFAFGGCALFATSYYSVQRTCQTTLFAPKLAAFTFWGWQLVILLAAISLPLGFTSSKEYAELEWPIDILITIVWVAYAVVFFGTLAKRKVKHIYVGNWFFGAFILTVAILHVVNNLEIPVTAMKSYSLYAGATDAMVQWWYGHNAVGFFLTAGFLGIMYYFVPKQAERPVYSYRLSIVHFWALITVYIWAGPHHLHYTALPDWAQSLGMVMSLILLAPSWGGMINGMMTLSGAWHKLRSDPILRFLVVSLAFYGMSTFEGPMMAIKTVNALSHYTDWTIGHVHAGALGWVAMVSIGALYHLVPKVFGREQMHSIGLINTHFWLATIGTVLYIASMWVNGIAQGLMWRAINDDGTLTYSFVESLEASHPGFVVRMIGGAIFFAGMLVMAYNTWRTVQAAKPAEYDAAKLEKNVGLLTLFMILAVSIGGLTQIVPLFFQDSVNEPVEGMKPYTALQLEGRDLYIREGCVGCHSQMIRPFRAETERYGHYSVAGESVYDHPFLWGSKRTGPDLARVGGRYSDDWHRAHLYNPRNVVPESKMPSYPWLVENTLDGKDTAKKMSALRMLGVPYTEEDIAGARDSVNGKTEMDAMVAYLQVLGTALTNKMSTFWSGYIALLTLGTIVALFWLIFATRKGESAGTTDQTMGHAFDGIEEYDNPLPRWWFLLFIGTLVFGILYLVLYPGLGNWKGVLPGYEGGWTQEKQWEREVAQADEKYGPIFAKYAAMSVEEVAQDPQAVKMGARLFANYCSICHGSDAKGSLGFPNLADQDWRWGGDAASIKTSILNGRIAAMPAWGQAIGEEGVKNVAAFVRKDLAGLPLPEGTDADLSAGKNVYAQTCAVCHGQGGEGMAALGAPKLNSAAGWIYGSSLGQLQQTIRHGRNGQMPAQQQYLGDDKVHLLAAYVYSLSQSTAYSYKVVRQFAIMTVVWGIVGMGLGVFIAAQLAWPFLNFDLPWTSFGRLRPLHTNAVIFAFGGCALFATSYYSVQRTCQTTLFAPKLAAFTFWGWQLVILLAAISLPLGFTSSKEYAELEWPIDILITIVWVAYAVVFFGTLAKRKVKHIYVGNWFFGAFILTVAILHVVNNLEIPVTAMKSYSLYAGATDAMVQWWYGHNAVGFFLTAGFLGIMYYFVPKQAERPVYSYRLSIVHFWALITVYIWAGPHHLHYTALPDWAQSLGMVMSLILLAPSWGGMINGMMTLSGAWHKLRSDPILRFLVVSLAFYGMSTFEGPMMAIKTVNALSHYTDWTIGHVHAGALGWVAMVSIGALYHLVPKVFGREQMHSIGLINTHFWLATIGTVLYIASMWVNGIAQGLMWRAINDDGTLTYSFVESLEASHPGFVVRMIGGAIFFAGMLVMAYNTWRTVQAAKPAEYDAAKLEKNVGLLTLFMILAVSIGGLTQIVPLFFQDSVNEPVEGMKPYTALQLEGRDLYIREGCVGCHSQMIRPFRAETERYGHYSVAGESVYDHPFLWGSKRTGPDLARVGGRYSDDWHRAHLYNPRNVVPESKMPSYPWLVENTLDGKDTAKKMSALRMLGVPYTEEDIAGARDSVNGKTEMDAMVAYLQVLGTALTNKMSTFWSGYIALLTLGTIVALFWLIFATRKGESAGTTDQTMGHAFDGIEEYDNPLPRWWFLLFIGTLVFGILYLVLYPGLGNWKGVLPGYEGGWTQEKQWEREVAQADEKYGPIFAKYAAMSVEEVAQDPQAVKMGARLFANYCSICHGSDAKGSLGFPNLADQDWRWGGDAASIKTSILNGRIAAMPAWGQAIGEEGVKNVAAFVRKDLAGLPLPEGTDADLSAGKNVYAQTCAVCHGQGGEGMAALGAPKLNSAAGWIYGSSLGQLQQTIRHGRNGQMPAQQQYLGDDKVHLLAAYVYSLSQMFVDNVVLAGVVTVGLMVAFLAGFGYFIWMFVDNVVLAGVVTVGLMVAFLAGFGYFIWMFVDNVVLAGVVTVGLMVAFLAGFGYFIWMFVDNVVLAGVVTVGLMVAFLAGFGYFIW

~~~S~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHH~GGGGTT~TTTSHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHTS~~SSHHHHHHHHHHHHHHHHHHHHHTTTT~~~~~TT~~S~HHHHHHHHHHHHHHHHHHHHHHHT~SSSS~~HHHHHHHHHHHHHHHHHHHHT~EEEEETTEEEES~~HHHHHHHHHHHHHHHHHHTTTHHHHHHHHHHHHHHHT~~BS~HHHHHHHHHHHHHHGGGGGGGGSTTSSS~HHHHHHHHHHHHHTHHHHHHHHHHHHGGGTT~TTHHHH~HHHHHHHHHHHHHHHHHHHHHHHTSHHHHHHHTBSHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHTT~SS~S~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~B~TTS~BS~~HHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS~S~~~~~~~~~SS~HHHHHHHHHHHHHHHHHHHTHHHHH~STTT~~~TT~~~~~HHHHHHHHHHHHTTGGGT~~~~~~S~HHHHHHHSS~~~GGGSTT~SS~~~~SB~SS~~~TT~TTTS~HHHHHHHHH~HHHHSTT~~~~~~THHHH~B~~~TTHHHHHHHHHHTT~~~~HHHHTTSSTTTTT~BHHHHHHHHHTTTTTTTTT~~~HHHHHHHHHHHHHHHHHHHHHHHHHTTT~~~S~~~~B~S~~BTTB~BB~~~~~HHHHHHHHHHHHHHHHHHHHSS~STT~~~~~TTSTT~~~HHHHHHHHHHHHHHHHHHHHHHHHHS~HHHHHH~HHHHHHHHHHHHHHTHHHH~TTS~~BTTB~~SSSS~~SS~~SHHHHHHHHHH~EE~~B~~~HHHH~HHHHHHHHHHHHHTTT~~~~~SS~~~~HHHHHHHHHHTTHHHH~TTS~~BTTTTB~~SS~GGG~SS~~SHHHHHHHHHH~B~~EE~~~TTTTHHHHHHHHHHHHHHH~~~~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHH~GGGGTT~TTTSHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHTS~~SSHHHHHHHHHHHHHHHHHHHHHTTTT~~~~STT~~S~HHHHHHHHHHHHHHHHHHHHHHHT~SSSS~~HHHHHHHHHHHHHHHHHHHHT~EEEEETTEEEES~~HHHHHHHHHHHHHHHHHHTTTHHHHHHHHHHHHHHHT~~BS~HHHHHHHHHHHHHHHHHTGGGGSTTSSS~HHHHHHHHHHHHHTHHHHHHHHHHHHGGGTTGGGHHHH~HHHHHHHHHHHHHHHHHHHHHHHTSHHHHHHHTBSHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHTT~SS~S~SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~B~TTSSBSS~HHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS~~~~S~S~~~~SS~HHHHHHHHHHHTTHHHHHHTHHHHH~STTT~~~TT~~~~~HHHHHHHHHHHHTTGGGT~~~~~~S~HHHHHHHSS~~~GGGGTT~SS~~~~SB~SS~~~TT~TTTS~HHHHHHHHH~HHHHSTT~~~~~~THHHH~B~~~TTHHHHHHHHHHTT~~~~HHHHTTSSTTTTT~BHHHHHHHHHTTTTTTTTT~~~HHHHHHHHHHHHHHHHHHHHHHHHHHTT~~SS~~~~~~S~~BTTB~B~~~~~~HHHHHHHHHHHHHHHHHHHHSTTSTT~~~~~TT~TTS~~HHHHHHHHHHHHHHHHHHHHHHHHHS~HHHHHH~HHHHHHHHHHHHHHTHHHH~TTS~~BTTB~~SSSS~~SS~~SHHHHHHHHHH~EE~~B~~~HHHH~HHHHHHHHHHHHHTTT~~~~~SS~~~~HHHHHHHHHHTTHHHH~TTS~~BTTTTB~~SS~GGG~SS~~SHHHHHHHHHH~B~~EE~~~TTTTHHHHHHHHHHHHHHH~~~~S~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHH~GGGGTT~TTTSHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHTS~~SSHHHHHHHHHHHHHHHHHHHHHTTTT~~~SSTT~~S~HHHHHHHHHHHHHHHHHHHHHHHT~SSSS~~HHHHHHHHHHHHHHHHHHHHT~EEEEETTEEEES~~HHHHHHHHHHHHHHHHHHTTTHHHHHHHHHHHHHHHT~~BS~HHHHHHHHHHHHHHHHHTGGGGSTTSSS~HHHHHHHHHHHHHTHHHHHHHHHHHHGGGTTGGGHHHH~HHHHHHHHHHHHHHHHHHHHHHHTSHHHHHHHTBSHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHTT~SS~S~SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~B~TTSSBS~~HHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS~SS~~~~~~~~SS~HHHHHHHHHHHTTHHHHHHTHHHHH~STTTS~~TT~~~~~HHHHHHHHHHHHHTGGGT~~~~~~S~HHHHHHH~S~~~GGGSTT~SS~~~~SB~SS~~~TT~TTTS~HHHHHHHHH~HHHHSTT~~~~~~THHHH~B~~~TTHHHHHHHHHHTT~~~~HHHHTTSSTTTTT~BHHHHHHHHHTTTTTTTTT~~~HHHHHHHHHHHHHHHHHHHHHHHHHHTT~~~S~~~~~~S~~BTTB~B~~~~~~HHHHHHHHHHHHHHHHHHHHSS~STT~~~~~TTSTT~~~HHHHHHHHHHHHHHHHHHHHHHHHHS~HHHHHH~HHHHHHHHHHHHHHTHHHH~TTS~~BTTB~~SSSS~~SS~~SHHHHHHHHHH~EE~~B~~~HHHH~HHHHHHHHHHHHHTTT~~~~~SS~~~~HHHHHHHHHHTTHHHH~TTS~~BTTTTB~~SS~GGG~SS~~SHHHHHHHHHH~B~~EE~~~TTTTHHHHHHHHHHHHHHH~~~~S~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHH~GGGGTT~TTTSHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHTS~~SSHHHHHHHHHHHHHHHHHHHHHTTTT~~~~STT~~S~HHHHHHHHHHHHHHHHHHHHHHHT~SSSS~~HHHHHHHHHHHHHHHHHHHHT~EEEEETTEEEES~~HHHHHHHHHHHHHHHHHHTTTHHHHHHHHHHHHHHHT~~BS~HHHHHHHHHHHHHHHHHTGGGSSTTSSS~HHHHHHHHHHHHHTHHHHHHHHHHHHGGGTT~TTHHHH~HHHHHHHHHHHHHHHHHHHHHHHTSHHHHHHHTBSHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHTT~SS~S~SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~B~TTSSBS~~HHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS~SS~~~~~~~~SS~HHHHHHHHHHHTTHHHHHHTHHHHH~STTT~~~TT~~~~~HHHHHHHHHHHHHTGGGT~~~~~~S~HHHHHHHSS~~~GGGSTT~SS~~~~SB~SS~~~TT~TTTS~HHHHHHHHH~HHHHSTT~~~~~~THHHH~B~~~TTHHHHHHHHHHTT~~~~HHHHTTSSTTTTT~BHHHHHHHHHTTTTTTTTT~~~HHHHHHHHHHHHHHHHHHHHHHHHHTTT~~~S~~~S~~S~EETTEEB~~~~~~HHHHHHHHHHHHHHHHHHHHSS~STT~~~~~TT~TT~~~HHHHHHHHHHHHHHHHHHHHHHHHHS~HHHHHH~HHHHHHHHHHHHHHTHHHH~TTS~~BTTB~~SSSS~~SS~~SHHHHHHHHHH~EE~~B~~~HHHH~HHHHHHHHHHHHHTTT~~~~~SS~~~~HHHHHHHHHHTTHHHH~TTS~~BTTTTB~~SS~GGG~SS~~SHHHHHHHHHH~B~~EE~~~TTTTHHHHHHHHHHHHHHH~~~~~~HHHHHHHHHHHHHHHHHHHHHHHH~~~~~HHHHHHHHHHHHHHHHHHHHHHHH~~~~~HHHHHHHHHHHHHHHHHHHHHHHH~~~~~HHHHHHHHHHHHHHHHHHHHHHHH~

T S T A Y S Y K V V R Q F A I M T V V W G I V G M G L G V F I A A Q L A W P F L N F D L P W T S F G R L R P L H T N A V I F A F G G C A L F A T S Y Y S V Q R T C Q T T L F A P K L A A F T F W G W Q L V I L L A A I S L P L G F T S S K E Y A E L E W P I D I L I T I V W V A Y A V V F F G T L A K R K V K H I Y V G N W F F G A F I L T V A I L H V V N N L E I P V T A M K S Y S L Y A G A T D A M V Q W W Y G H N A V G F F L T A G F L G I M Y Y F V P K Q A E R P V Y S Y R L S I V H F W A L I T V Y I W A G P H H L H Y T A L P D W A Q S L G M V M S L I L L A P S W G G M I N G M M T L S G A W H K L R S D P I L R F L V V S L A F Y G M S T F E G P M M A I K T V N A L S H Y T D W T I G H V H A G A L G W V A M V S I G A L Y H L V P K V F G R E Q M H S I G L I N T H F W L A T I G T V L Y I A S M W V N G I A Q G L M W R A I N D D G T L T Y S F V E S L E A S H P G F V V R M I G G A I F F A G M L V M A Y N T W R T V Q A A K P A E Y D A A K L E K N V G L L T L F M I L A V S I G G L T Q I V P L F F Q D S V N E P V E G M K P Y T A L Q L E G R D L Y I R E G C V G C H S Q M I R P F R A E T E R Y G H Y S V A G E S V Y D H P F L W G S K R T G P D L A R V G G R Y S D D W H R A H L Y N P R N V V P E S K M P S Y P W L V E N T L D G K D T A K K M S A L R M L G V P Y T E E D I A G A R D S V N G K T E M D A M V A Y L Q V L G T A L T N K M S T F W S G Y I A L L T L G T I V A L F W L I F A T R K G E S A G T T D Q T M G H A F D G I E E Y D N P L P R W W F L L F I G T L V F G I L Y L V L Y P G L G N W K G V L P G Y E G G W T Q E K Q W E R E V A Q A D E K Y G P I F A K Y A A M S V E E V A Q D P Q A V K M G A R L F A N Y C S I C H G S D A K G S L G F P N L A D Q D W R W G G D A A S I K T S I L N G R I A A M P A W G Q A I G E E G V K N V A A F V R K D L A G L P L P E G T D A D L S A G K N V Y A Q T C A V C H G Q G G E G M A A L G A P K L N S A A G W I Y G S S L G Q L Q Q T I R H G R N G Q M P A Q Q Q Y L G D D K V H L L A A Y V Y S L S Q A Y S Y K V V R Q F A I M T V V W G I V G M G L G V F I A A Q L A W P F L N F D L P W T S F G R L R P L H T N A V I F A F G G C A L F A T S Y Y S V Q R T C Q T T L F A P K L A A F T F W G W Q L V I L L A A I S L P L G F T S S K E Y A E L E W P I D I L I T I V W V A Y A V V F F G T L A K R K V K H I Y V G N W F F G A F I L T V A I L H V V N N L E I P V T A M K S Y S L Y A G A T D A M V Q W W Y G H N A V G F F L T A G F L G I M Y Y F V P K Q A E R P V Y S Y R L S I V H F W A L I T V Y I W A G P H H L H Y T A L P D W A Q S L G M V M S L I L L A P S W G G M I N G M M T L S G A W H K L R S D P I L R F L V V S L A F Y G M S T F E G P M M A I K T V N A L S H Y T D W T I G H V H A G A L G W V A M V S I G A L Y H L V P K V F G R E Q M H S I G L I N T H F W L A T I G T V L Y I A S M W V N G I A Q G L M W R A I N D D G T L T Y S F V E S L E A S H P G F V V R M I G G A I F F A G M L V M A Y N T W R T V Q A A K P A E Y D A A K L E K N V G L L T L F M I L A V S I G G L T Q I V P L F F Q D S V N E P V E G M K P Y T A L Q L E G R D L Y I R E G C V G C H S Q M I R P F R A E T E R Y G H Y S V A G E S V Y D H P F L W G S K R T G P D L A R V G G R Y S D D W H R A H L Y N P R N V V P E S K M P S Y P W L V E N T L D G K D T A K K M S A L R M L G V P Y T E E D I A G A R D S V N G K T E M D A M V A Y L Q V L G T A L T N K M S T F W S G Y I A L L T L G T I V A L F W L I F A T R K G E S A G T T D Q T M G H A F D G I E E Y D N P L P R W W F L L F I G T L V F G I L Y L V L Y P G L G N W K G V L P G Y E G G W T Q E K Q W E R E V A Q A D E K Y G P I F A K Y A A M S V E E V A Q D P Q A V K M G A R L F A N Y C S I C H G S D A K G S L G F P N L A D Q D W R W G G D A A S I K T S I L N G R I A A M P A W G Q A I G E E G V K N V A A F V R K D L A G L P L P E G T D A D L S A G K N V Y A Q T C A V C H G Q G G E G M A A L G A P K L N S A A G W I Y G S S L G Q L Q Q T I R H G R N G Q M P A Q Q Q Y L G D D K V H L L A A Y V Y S L S Q S T A Y S Y K V V R Q F A I M T V V W G I V G M G L G V F I A A Q L A W P F L N F D L P W T S F G R L R P L H T N A V I F A F G G C A L F A T S Y Y S V Q R T C Q T T L F A P K L A A F T F W G W Q L V I L L A A I S L P L G F T S S K E Y A E L E W P I D I L I T I V W V A Y A V V F F G T L A K R K V K H I Y V G N W F F G A F I L T V A I L H V V N N L E I P V T A M K S Y S L Y A G A T D A M V Q W W Y G H N A V G F F L T A G F L G I M Y Y F V P K Q A E R P V Y S Y R L S I V H F W A L I T V Y I W A G P H H L H Y T A L P D W A Q S L G M V M S L I L L A P S W G G M I N G M M T L S G A W H K L R S D P I L R F L V V S L A F Y G M S T F E G P M M A I K T V N A L S H Y T D W T I G H V H A G A L G W V A M V S I G A L Y H L V P K V F G R E Q M H S I G L I N T H F W L A T I G T V L Y I A S M W V N G I A Q G L M W R A I N D D G T L T Y S F V E S L E A S H P G F V V R M I G G A I F F A G M L V M A Y N T W R T V Q A A K P A E Y D A A K L E K N V G L L T L F M I L A V S I G G L T Q I V P L F F Q D S V N E P V E G M K P Y T A L Q L E G R D L Y I R E G C V G C H S Q M I R P F R A E T E R Y G H Y S V A G E S V Y D H P F L W G S K R T G P D L A R V G G R Y S D D W H R A H L Y N P R N V V P E S K M P S Y P W L V E N T L D G K D T A K K M S A L R M L G V P Y T E E D I A G A R D S V N G K T E M D A M V A Y L Q V L G T A L T N K M S T F W S G Y I A L L T L G T I V A L F W L I F A T R K G E S A G T T D Q T M G H A F D G I E E Y D N P L P R W W F L L F I G T L V F G I L Y L V L Y P G L G N W K G V L P G Y E G G W T Q E K Q W E R E V A Q A D E K Y G P I F A K Y A A M S V E E V A Q D P Q A V K M G A R L F A N Y C S I C H G S D A K G S L G F P N L A D Q D W R W G G D A A S I K T S I L N G R I A A M P A W G Q A I G E E G V K N V A A F V R K D L A G L P L P E G T D A D L S A G K N V Y A Q T C A V C H G Q G G E G M A A L G A P K L N S A A G W I Y G S S L G Q L Q Q T I R H G R N G Q M P A Q Q Q Y L G D D K V H L L A A Y V Y S L S Q S T A Y S Y K V V R Q F A I M T V V W G I V G M G L G V F I A A Q L A W P F L N F D L P W T S F G R L R P L H T N A V I F A F G G C A L F A T S Y Y S V Q R T C Q T T L F A P K L A A F T F W G W Q L V I L L A A I S L P L G F T S S K E Y A E L E W P I D I L I T I V W V A Y A V V F F G T L A K R K V K H I Y V G N W F F G A F I L T V A I L H V V N N L E I P V T A M K S Y S L Y A G A T D A M V Q W W Y G H N A V G F F L T A G F L G I M Y Y F V P K Q A E R P V Y S Y R L S I V H F W A L I T V Y I W A G P H H L H Y T A L P D W A Q S L G M V M S L I L L A P S W G G M I N G M M T L S G A W H K L R S D P I L R F L V V S L A F Y G M S T F E G P M M A I K T V N A L S H Y T D W T I G H V H A G A L G W V A M V S I G A L Y H L V P K V F G R E Q M H S I G L I N T H F W L A T I G T V L Y I A S M W V N G I A Q G L M W R A I N D D G T L T Y S F V E S L E A S H P G F V V R M I G G A I F F A G M L V M A Y N T W R T V Q A A K P A E Y D A A K L E K N V G L L T L F M I L A V S I G G L T Q I V P L F F Q D S V N E P V E G M K P Y T A L Q L E G R D L Y I R E G C V G C H S Q M I R P F R A E T E R Y G H Y S V A G E S V Y D H P F L W G S K R T G P D L A R V G G R Y S D D W H R A H L Y N P R N V V P E S K M P S Y P W L V E N T L D G K D T A K K M S A L R M L G V P Y T E E D I A G A R D S V N G K T E M D A M V A Y L Q V L G T A L T N K M S T F W S G Y I A L L T L G T I V A L F W L I F A T R K G E S A G T T D Q T M G H A F D G I E E Y D N P L P R W W F L L F I G T L V F G I L Y L V L Y P G L G N W K G V L P G Y E G G W T Q E K Q W E R E V A Q A D E K Y G P I F A K Y A A M S V E E V A Q D P Q A V K M G A R L F A N Y C S I C H G S D A K G S L G F P N L A D Q D W R W G G D A A S I K T S I L N G R I A A M P A W G Q A I G E E G V K N V A A F V R K D L A G L P L P E G T D A D L S A G K N V Y A Q T C A V C H G Q G G E G M A A L G A P K L N S A A G W I Y G S S L G Q L Q Q T I R H G R N G Q M P A Q Q Q Y L G D D K V H L L A A Y V Y S L S Q M F V D N V V L A G V V T V G L M V A F L A G F G Y F I W M F V D N V V L A G V V T V G L M V A F L A G F G Y F I W M F V D N V V L A G V V T V G L M V A F L A G F G Y F I W M F V D N V V L A G V V T V G L M V A F L A G F G Y F I W

AH

UNSTRUCTURED

1FER

AFVVTDNCIKCKYTDCVEVCPVDCFYEGPNFLVIHPDECIDCALCEPECPAQAIFSEDEVPEDMQEFIQLNAELAEVWPNITEKKDPLPDAEDWDGVKGKLQHLER

~EEE~GGGTTT~~~HHHHH~SS~~EEE~SS~EEE~TTT~~~~~~SGGG~TT~~EEEGGG~~GGGTHHHHHHHHHHTTS~B~~S~~~~~TTHHHHTT~S~GGGG~~~

A F V V T D N C I K C K Y T D C V E V C P V D C F Y E G P N F L V I H P D E C I D C A L C E P E C P A Q A I F S E D E V P E D M Q E F I Q L N A E L A E V W P N I T E K K D P L P D A E D W D G V K G K L Q H L E R

UNSTRUCTURED

AH

5UOJ

RPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPL

~~~EEEEEETTEEEEEETTEEEEEEEE~SSSEEEEEEEETTT~~EEEEEEESSTTSSHHHHHHHHHHHHHHHH~~~TTB~~~SEEE~S~SSGGG~~~~EEEEE~~~~BHHHHHHT~~~~HHHHHHHHHHHHHHHHHHHHTT~~~~~~SGGGEEE~TT~~EEE~~~~~~~~SS~HHHHTS~HHHHTT~SS~~TTHHHHHHHHHHHHHHHSS~S~~~SSHHHHHHHHHHHH~~~~HHHHTT~~~HHHHHHHHHS~~~~~~~GGGTSTT~~HHHHHHHHHHS~SSTTTS~~HHHHHTSGGGTTT~~GGG~~~~~~~~~GGGG~~~~HHHHHHHHHHHHHT~~~~~~

R P T F Y R Q E L N K T I W E V P E R Y Q N L S P V G S G A Y G S V C A A F D T K T G H R V A V K K L S R P F Q S I I H A K R T Y R E L R L L K H M K H E N V I G L L D V F T P A R S L E E F N D V Y L V T H L M G A D L N N I V K C Q K L T D D H V Q F L I Y Q I L R G L K Y I H S A D I I H R D L K P S N L A V N E D C E L K I L D F G L A M T G Y V A T R W Y R A P E I M L N W M H Y N Q T V D I W S V G C I M A E L L T G R T L F P G T D H I D Q L K L I L R L V G T P G A E L L K K I S S E S A R N Y I Q S L A Q M P K M N F A N V F I G A N P L A V D L L E K M L V L D S D K R I T A A Q A L A H A Y F A Q Y H D P D D E P V A D P Y D Q S F E S R D L L I D E W K S L T Y D E V I S F V P P P L

AH

UNSTRUCTURED

4IHU

GPGDAVRVTSSKLVTQPGTSNPKAVVSFYEDFLCPACGIFERGFGPTVSKLVDIGAVAADYTVAILDSASNQHYSSRAAAAAYCVADESIEAFRRFHAALFSKDIQPAELGKDFPDNARLIELAREAGVVGKVPDCINSGKYIEKVDGLAAAVNVHATPTVRVNGTEYEWSTPAALVAKIKEIVGDVPGIDSAAATATSADKKDGVAGPGDAVRVTSSKLVTQPGTSNPKAVVSFYEDFLCPACGIFERGFGPTVSKLVDIGAVAADYTVAILDSASNQHYSSRAAAAAYCVADESIEAFRRFHAALFSKDIQPAELGKDFPDNARLIELAREAGVVGKVPDCINSGKYIEKVDGLAAAVNVHATPTVRVNGTEYEWSTPAALVAKIKEIVGDVPGIDSAAATATSA

~~SSSEEE~~TT~~B~TTSS~BS~EEEEE~~TT~HHHHHHHHHHHHHHHHHHHTTS~EEEE~~~TT~~GGGTTHHHHHHHHHHHHHHH~HHHHHHHHHHHTSTTT~~~TT~S~~~~HHHHHHHHHHHT~~TTHHHHHHTTTTHHHHHHHHHHHT~~SSSEEEETTEE~~~~~HHHHHHHHHHHH~S~TTHHHHHHHHT~~~TTGGGSS~TTSEEE~~TT~~B~TTS~~BS~EEEEE~~TT~HHHHHHHHHHHHHHHHHHHTTS~EEEE~~~TT~~GGGTTHHHHHHHHHHHHHHH~HHHHHHHHHHHTSTTT~~~TTSS~~~~HHHHHHHHHHTT~~TTHHHHHHTTTTHHHHHHHHHHHT~~SSSEEEETTEE~~~~~HHHHHHHHHHHH~S~TTHHHHHHTTS~~

G P G D A V R V T S S K L V T Q P G T S N P K A V V S F Y E D F L C P A C G I F E R G F G P T V S K L V D I G A V A A D Y T V A I L D S A S N Q H Y S S R A A A A A Y C V A D E S I E A F R R F H A A L F S K D I Q P A E L G K D F P D N A R L I E L A R E A G V V G K V P D C I N S G K Y I E K V D G L A A A V N V H A T P T V R V N G T E Y E W S T P A A L V A K I K E I V G D V P G I D S A A A T A T S A D K K D G V A G P G D A V R V T S S K L V T Q P G T S N P K A V V S F Y E D F L C P A C G I F E R G F G P T V S K L V D I G A V A A D Y T V A I L D S A S N Q H Y S S R A A A A A Y C V A D E S I E A F R R F H A A L F S K D I Q P A E L G K D F P D N A R L I E L A R E A G V V G K V P D C I N S G K Y I E K V D G L A A A V N V H A T P T V R V N G T E Y E W S T P A A L V A K I K E I V G D V P G I D S A A A T A T S A

AH

UNSTRUCTURED

6F0R

VSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVQNARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPMLFILFISWTAFWSTSYEANVTLVVSTLIAHIAFNILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFFVSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVQNARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPMLFILFISWTAFWSTSYEANVTLVVSTLIAHIAFNILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFFVSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVQNARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPMLFILFISWTAFWSTSYEANVTLVVSTLIAHIAFNILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFFVSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVQNARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPMLFILFISWTAFWSTSYEANVTLVVSTLIAHIAFNILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFFVSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVQNARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPMLFILFISWTAFWSTSYEANVTLVVSTLIAHIAFNILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFF

~~~~~~SSS~~EEEEEEEEEEEEEEEETTTTEEEEEEEEEEEEE~GGG~~~HHHH~~SSEE~~TTTS~~~~EEESSBSS~~EEEEEEEEE~TT~EEEEEEEEEEEEE~~~~~TTTTS~EEEEEEEEEEE~~SS~~EEEEE~GGG~EE~TT~~~TTEEEEEEEEEEEEEEEESSSSEEEEEEEEEEEEE~~TTHHHHTHHHHHHHHHHHGGGGG~~~HHHHHHHHHHHHHHHHHHHHHHHHSS~~~SS~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~~~~~~~SSS~~EEEEEEEEEEEEEEEETTTTEEEEEEEEEEEEE~GGG~~~HHHHS~SSEE~~TTTS~~~~EEESSBSS~~EEEEEEEEE~TT~EEEEEEEEEEEEE~~~~~TTTTS~EEEEEEEEEEE~~SS~~EEEEE~GGG~EE~TT~~~TTEEEEEEEEEEEEEEEESSSSEEEEEEEEEEEEE~~TTHHHHTHHHHHHHHHHHGGGGG~~~HHHHHHHHHHHHHHHHHHHHHHHHSS~~~SS~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~~~~~~~SSS~~EEEEEEEEEEEEEEEETTTTEEEEEEEEEEEEE~GGG~~~HHHH~~SSEE~~TTTS~~~~EEESSBSS~~EEEEEEEEE~TT~EEEEEEEEEEEEE~~~~~TTTTS~EEEEEEEEEEE~~SS~~EEEEE~GGG~EE~TT~~~TTEEEEEEEEEEEEEEEESSSSEEEEEEEEEEEEE~~TTHHHHTHHHHHHHHHHHGGGGG~~~HHHHHHHHHHHHHHHHHHHHHHHHSS~~~SS~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~~~~~~~SSS~~EEEEEEEEEEEEEEEETTTTEEEEEEEEEEEEE~GGG~~~HHHH~~SSEE~~TTTS~~~~EEESSBSS~~EEEEEEEEE~TT~EEEEEEEEEEEEE~~~~~TTTTS~EEEEEEEEEEE~~SS~~EEEEE~GGG~EE~TT~~~TTEEEEEEEEEEEEEEEESSSSEEEEEEEEEEEEE~~TTHHHHTHHHHHHHHHHHGGGGG~~~HHHHHHHHHHHHHHHHHHHHHHHHSS~~~SS~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~~~~~~~SSS~~EEEEEEEEEEEEEEEETTTTEEEEEEEEEEEEE~GGG~~~HHHH~~SSEE~~TTTS~~~~EEESSBSS~~EEEEEEEEE~TT~EEEEEEEEEEEEE~~~~~TTTTS~EEEEEEEEEEE~~SS~~EEEEE~GGG~EE~TT~~~TTEEEEEEEEEEEEEEEESSSSEEEEEEEEEEEEE~~TTHHHHTHHHHHHHHHHHGGGGG~~~HHHHHHHHHHHHHHHHHHHHHHHHSS~~~SS~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~

V S P P P P I A D E P L T V N T G I Y L I E C Y S L D D K A E T F K V N A F L S L S W K D R R L A F D P V R S G V R V K T Y E P E A I W I P E I R F V N V Q N A R D A D V V D I S V S P D G T V Q Y L E R F S A R V L S P L D F R R Y P F D S Q T L H I Y L I V R S V D T R N I V L A V D L E K V G K N D D V F L T G W D I E S F T A V V K P A N F A L E D R L E S K L D Y Q L R I S R Q Y F S Y I P N I I L P M L F I L F I S W T A F W S T S Y E A N V T L V V S T L I A H I A F N I L V E T N L P K T P Y M T Y T G A I I F M I Y L F Y F V A V I E V T V Q H Y L K V E S Q P A R A A S I T R A S R I A F P V V F L L A N I I L A F L F F V S P P P P I A D E P L T V N T G I Y L I E C Y S L D D K A E T F K V N A F L S L S W K D R R L A F D P V R S G V R V K T Y E P E A I W I P E I R F V N V Q N A R D A D V V D I S V S P D G T V Q Y L E R F S A R V L S P L D F R R Y P F D S Q T L H I Y L I V R S V D T R N I V L A V D L E K V G K N D D V F L T G W D I E S F T A V V K P A N F A L E D R L E S K L D Y Q L R I S R Q Y F S Y I P N I I L P M L F I L F I S W T A F W S T S Y E A N V T L V V S T L I A H I A F N I L V E T N L P K T P Y M T Y T G A I I F M I Y L F Y F V A V I E V T V Q H Y L K V E S Q P A R A A S I T R A S R I A F P V V F L L A N I I L A F L F F V S P P P P I A D E P L T V N T G I Y L I E C Y S L D D K A E T F K V N A F L S L S W K D R R L A F D P V R S G V R V K T Y E P E A I W I P E I R F V N V Q N A R D A D V V D I S V S P D G T V Q Y L E R F S A R V L S P L D F R R Y P F D S Q T L H I Y L I V R S V D T R N I V L A V D L E K V G K N D D V F L T G W D I E S F T A V V K P A N F A L E D R L E S K L D Y Q L R I S R Q Y F S Y I P N I I L P M L F I L F I S W T A F W S T S Y E A N V T L V V S T L I A H I A F N I L V E T N L P K T P Y M T Y T G A I I F M I Y L F Y F V A V I E V T V Q H Y L K V E S Q P A R A A S I T R A S R I A F P V V F L L A N I I L A F L F F V S P P P P I A D E P L T V N T G I Y L I E C Y S L D D K A E T F K V N A F L S L S W K D R R L A F D P V R S G V R V K T Y E P E A I W I P E I R F V N V Q N A R D A D V V D I S V S P D G T V Q Y L E R F S A R V L S P L D F R R Y P F D S Q T L H I Y L I V R S V D T R N I V L A V D L E K V G K N D D V F L T G W D I E S F T A V V K P A N F A L E D R L E S K L D Y Q L R I S R Q Y F S Y I P N I I L P M L F I L F I S W T A F W S T S Y E A N V T L V V S T L I A H I A F N I L V E T N L P K T P Y M T Y T G A I I F M I Y L F Y F V A V I E V T V Q H Y L K V E S Q P A R A A S I T R A S R I A F P V V F L L A N I I L A F L F F V S P P P P I A D E P L T V N T G I Y L I E C Y S L D D K A E T F K V N A F L S L S W K D R R L A F D P V R S G V R V K T Y E P E A I W I P E I R F V N V Q N A R D A D V V D I S V S P D G T V Q Y L E R F S A R V L S P L D F R R Y P F D S Q T L H I Y L I V R S V D T R N I V L A V D L E K V G K N D D V F L T G W D I E S F T A V V K P A N F A L E D R L E S K L D Y Q L R I S R Q Y F S Y I P N I I L P M L F I L F I S W T A F W S T S Y E A N V T L V V S T L I A H I A F N I L V E T N L P K T P Y M T Y T G A I I F M I Y L F Y F V A V I E V T V Q H Y L K V E S Q P A R A A S I T R A S R I A F P V V F L L A N I I L A F L F F

BS

AH

4LLA

SKKPSLSVQPGPVMAPGESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVVSSKKPSLSVQPGPVMAPGESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVVSSKKPSLSVQPGPVMAPGESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVVS

~~~~EEEEEHHSEE~TT~~EEEEEEESS~~SEEEEEETT~~~EEEEE~B~SSTT~EEEEEEE~S~~GGG~EEEEEEEE~SS~~~B~~~~~~EEEEE~S~SS~~~EEEEES~SEE~TT~~~EEEEEESS~~SEEEEEESSS~~~~EEEE~EEETTEEEEEEE~~S~~GGG~EEEEEEEEETTEEEEE~~~~~~EEEEE~~~~~EEEEES~SEE~TT~~EEEEEEESS~~SEEEEEETT~~~EEEEE~B~SSTT~EEEEEEE~S~~GGG~EEEEEEEE~SSS~~B~~~~~~EEEEEEEEES~~~EEEEES~SEE~TT~~~EEEEEESS~~SEEEEEESSS~S~~EEEE~EEETTEEEEEEE~~S~~TTT~EEEEEEEE~TT~TTEEE~~~~~EEEEE~~~~~EEEEES~SEE~TT~~EEEEEEESS~~SEEEEEETT~S~EEEEE~B~SSTT~EEEEEEE~S~~GGG~EEEEEEEE~SS~~~B~~~~~~EEEEE~S~SS~~~EEEEES~SEE~TT~~~EEEEEESS~~SEEEEEESSS~S~~EEEE~EEETTEEEEEEE~SS~~GGG~EEEEEEEE~TT~TTBB~~~~~~EEEEE~

S K K P S L S V Q P G P V M A P G E S L T L Q C V S D V G Y D R F V L Y K E G E R D L R Q L P G R Q P Q A G L S Q A N F T L G P V S R S Y G G Q Y R C Y G A H N L S S E C S A P S D P L D I L I T G Q I R G T P F I S V Q P G P T V A S G E N V T L L C Q S W R Q F H T F L L T K A G A A D A P L R L R S I H E Y P K Y Q A E F P M S P V T S A H A G T Y R C Y G S L N S D P Y L L S H P S E P L E L V V S S K K P S L S V Q P G P V M A P G E S L T L Q C V S D V G Y D R F V L Y K E G E R D L R Q L P G R Q P Q A G L S Q A N F T L G P V S R S Y G G Q Y R C Y G A H N L S S E C S A P S D P L D I L I T G Q I R G T P F I S V Q P G P T V A S G E N V T L L C Q S W R Q F H T F L L T K A G A A D A P L R L R S I H E Y P K Y Q A E F P M S P V T S A H A G T Y R C Y G S L N S D P Y L L S H P S E P L E L V V S S K K P S L S V Q P G P V M A P G E S L T L Q C V S D V G Y D R F V L Y K E G E R D L R Q L P G R Q P Q A G L S Q A N F T L G P V S R S Y G G Q Y R C Y G A H N L S S E C S A P S D P L D I L I T G Q I R G T P F I S V Q P G P T V A S G E N V T L L C Q S W R Q F H T F L L T K A G A A D A P L R L R S I H E Y P K Y Q A E F P M S P V T S A H A G T Y R C Y G S L N S D P Y L L S H P S E P L E L V V S

BS

UNSTRUCTURED

4YXY

VEELLKLAKAAYYSGTTVEEAYKLALKLGISVEELLKLAEAAYYSGTTVEEAYKLALKLGISVEELLKLAKAAYYSGTTVEEAYKLALKLGVEELLKLAKAAYYSGTTVEEAYKLALKLGISVEELLKLAEAAYYSGTTVEEAYKLALKLGISVEELLKLAKAAYYSGTTVEEAYKLALKLGVEELLKLAKAAYYSGTTVEEAYKLALKLGISVEELLKLAEAAYYSGTTVEEAYKLALKLGISVEELLKLAKAAYYSGTTVEEAYKLALKLGVEELLKLAKAAYYSGTTVEEAYKLALKLGISVEELLKLAEAAYYSGTTVEEAYKLALKLGISVEELLKLAKAAYYSGTTVEEAYKLALKLG

~HHHHHHHHHHHHTTS~HHHHHHHHHHTT~~HHHHHHHHHHHHHHTS~HHHHHHHHHHTT~~HHHHHHHHHHHHHHTS~HHHHHHHHHHT~~HHHHHHHHHHHHHSS~HHHHHHHHHHTT~~HHHHHHHHHHHHHHTS~HHHHHHHHHHTT~~HHHHHHHHHHHHHHTS~HHHHHHHHHHT~~HHHHHHHHHHHHHTS~HHHHHHHHHHEEE~HHHHHHHHHHHHHHTS~HHHHHHHHHHTT~~HHHHHHHHHHHHHHTS~HHHHHHHHHHT~~HHHHHHHHHHHHHTS~HHHHHHHHHHTT~~HHHHHHHHHHHHHHTS~HHHHHHHHHHTT~~HHHHHHHHHHHHHHTS~HHHHHHHHHHT~

V E E L L K L A K A A Y Y S G T T V E E A Y K L A L K L G I S V E E L L K L A E A A Y Y S G T T V E E A Y K L A L K L G I S V E E L L K L A K A A Y Y S G T T V E E A Y K L A L K L G V E E L L K L A K A A Y Y S G T T V E E A Y K L A L K L G I S V E E L L K L A E A A Y Y S G T T V E E A Y K L A L K L G I S V E E L L K L A K A A Y Y S G T T V E E A Y K L A L K L G V E E L L K L A K A A Y Y S G T T V E E A Y K L A L K L G I S V E E L L K L A E A A Y Y S G T T V E E A Y K L A L K L G I S V E E L L K L A K A A Y Y S G T T V E E A Y K L A L K L G V E E L L K L A K A A Y Y S G T T V E E A Y K L A L K L G I S V E E L L K L A E A A Y Y S G T T V E E A Y K L A L K L G I S V E E L L K L A K A A Y Y S G T T V E E A Y K L A L K L G

AH

UNSTRUCTURED

3C8C

SLRSVSDSVDEIVDGVSKTTAEVINGRKSIAQYATSLIENNPEPDNVRTIISQPLIKNTFLLVGFGLEKDGSNINNDPSWNPGPTWDPRVRPWYKDAKNAGKLVITAPYADSASGEILVSVATPVKDSATGQFLGSIFYDVSLAELAELVNEVKLFDAGYVFIVSEDGTTIAHPKKEFNGKPSEFLGESKINVDTHQVIINGKPYAVSFSDVEGEDWYVGVVIDEEIAYAALDELRRSSLRSVSDSVDEIVDGVSKTTAEVINGRKSIAQYATSLIENNPEPDNVRTIISQPLIKNTFLLVGFGLEKDGSNINNDPSWNPGPTWDPRVRPWYKDAKNAGKLVITAPYADSASGEILVSVATPVKDSATGQFLGSIFYDVSLAELAELVNEVKLFDAGYVFIVSEDGTTIAHPKKEFNGKPSEFLGESKINVDTHQVIINGKPYAVSFSDVEGEDWYVGVVIDEEIAYAALDELRRS

~~~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHSSHHHHHHSS~EEEEETTT~~EEES~TT~~~~SS~~GGGSHHHHHHHHHTS~EE~~~EE~TTT~~EEEEEEEEEE~TTT~~EEEEEEEEE~HHHHHHHHT~S~~TTSEEEEEEETTS~EEE~SSGGGTT~~~TTTS~~S~~~S~EEEEETTEEEEEEEEE~TTSSEEEEEEE~HHHHHHHHHHHHT~~~~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHSSHHHHHH~S~EEEEETTTS~EEES~TT~~~~TT~~GGGSHHHHHHHHHSS~EE~~~EE~TTT~~EEEEEEEEEE~TTT~~EEEEEEEEE~HHHHHHHHTTS~~TTSEEEEEE~TT~~EEE~SSGGGTT~~~TTTS~~S~~~S~EEEEETTEEEEEEEEE~TTSS~EEEEEEEHHHHHHHHHHHHH~

S L R S V S D S V D E I V D G V S K T T A E V I N G R K S I A Q Y A T S L I E N N P E P D N V R T I I S Q P L I K N T F L L V G F G L E K D G S N I N N D P S W N P G P T W D P R V R P W Y K D A K N A G K L V I T A P Y A D S A S G E I L V S V A T P V K D S A T G Q F L G S I F Y D V S L A E L A E L V N E V K L F D A G Y V F I V S E D G T T I A H P K K E F N G K P S E F L G E S K I N V D T H Q V I I N G K P Y A V S F S D V E G E D W Y V G V V I D E E I A Y A A L D E L R R S S L R S V S D S V D E I V D G V S K T T A E V I N G R K S I A Q Y A T S L I E N N P E P D N V R T I I S Q P L I K N T F L L V G F G L E K D G S N I N N D P S W N P G P T W D P R V R P W Y K D A K N A G K L V I T A P Y A D S A S G E I L V S V A T P V K D S A T G Q F L G S I F Y D V S L A E L A E L V N E V K L F D A G Y V F I V S E D G T T I A H P K K E F N G K P S E F L G E S K I N V D T H Q V I I N G K P Y A V S F S D V E G E D W Y V G V V I D E E I A Y A A L D E L R R S

AH

BS

2WLA

NTLVENIYASVTHNSKNEKTKAVLNQAVADLSVAASIVHQVHWYMRGPGFLYLHPKMDELLDSLNANLDEVSERLITIGGAPYSTLAEFSKHSKLDEAKGTYDKTVAQHLARLVEVYLYLSSLYQVGLDITDEEGDAGTNDLFTAAKTEAEKTIWMLQAERGQGPAL

~~HHHHHHHHHT~~~TTHHHHHHHHHHHHHHHHHHHHHHHHHHH~~STTHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT~~~~~SHHHHHHH~S~~~~~~~TE~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHT~HHHHHHHHHHHHHHHHHHHHHHHHTT~~~~~

N T L V E N I Y A S V T H N S K N E K T K A V L N Q A V A D L S V A A S I V H Q V H W Y M R G P G F L Y L H P K M D E L L D S L N A N L D E V S E R L I T I G G A P Y S T L A E F S K H S K L D E A K G T Y D K T V A Q H L A R L V E V Y L Y L S S L Y Q V G L D I T D E E G D A G T N D L F T A A K T E A E K T I W M L Q A E R G Q G P A L

AH

UNSTRUCTURED

2EQW

GSSGSSGEKPYVCTECGKAFIRKSHFITHERIHTGESGPSSG

~~S~~~~~~SEE~SSS~~EESSSSHHHHHHHHH~S~~~SS~~

G S S G S S G E K P Y V C T E C G K A F I R K S H F I T H E R I H T G E S G P S S G

UNSTRUCTURED

BEND

4H15

SIEFLNLRGKRALITAGTKGAGAATVSLFLELGAQVLTTARARPEGLPEELFVEADLTTKEGCAIVAEATRQRLGGVDVIVHLGGSSAAGGGFSALSDDDWYNELSLNLFAAVRLDRQLVPDVARGSGVVVHVTSIQRVLPLPESTTAYAAAKAALSTYSKASKEVSPKGVRVVRVSPGWIETEASVRLAERLAKQAGTDLEGGKKIIDGLGGIPLGRPAKPEEVANLIAFLASDRAASITGAEYTIDGGTVPTASIEFLNLRGKRALITAGTKGAGAATVSLFLELGAQVLTTARARPEGLPEELFVEADLTTKEGCAIVAEATRQRLGGVDVIVHLGGSSAAGGGFSALSDDDWYNELSLNLFAAVRLDRQLVPDVARGSGVVVHVTSIQRVLPLPESTTAYAAAKAALSTYSKASKEVSPKGVRVVRVSPGWIETEASVRLAERLAKQAGTDLEGGKKIIDGLGGIPLGRPAKPEEVANLIAFLASDRAASITGAEYTIDGGTVPTASIEFLNLRGKRALITAGTKGAGAATVSLFLELGAQVLTTARARPEGLPEELFVEADLTTKEGCAIVAEATRQRLGGVDVIVHLGGSSAAGGGFSALSDDDWYNELSLNLFAAVRLDRQLVPDVARGSGVVVHVTSIQRVLPLPESTTAYAAAKAALSTYSKASKEVSPKGVRVVRVSPGWIETEASVRLAERLAKQAGTDLEGGKKIIDGLGGIPLGRPAKPEEVANLIAFLASDRAASITGAEYTIDGGTVPTASIEFLNLRGKRALITAGTKGAGAATVSLFLELGAQVLTTARARPEGLPEELFVEADLTTKEGCAIVAEATRQRLGGVDVIVHLGGSSAAGGGFSALSDDDWYNELSLNLFAAVRLDRQLVPDVARGSGVVVHVTSIQRVLPLPESTTAYAAAKAALSTYSKASKEVSPKGVRVVRVSPGWIETEASVRLAERLAKQAGTDLEGGKKIIDGLGGIPLGRPAKPEEVANLIAFLASDRAASITGAEYTIDGGTVPTA

~~~~~~~TT~EEEES~~SSHHHHHHHHHHHHTT~EEEEEESS~~TTS~TTTEEE~~TTSHHHHHHHHHHHHHHTSS~SEEE~~~~~~~~SS~GGG~~HHHHHHHHHHHTHHHHHHHHHHS~~~~S~~EEEEEE~~GGGTS~~TTT~HHHHHHHHHHHHHHH~~TTTGGGTEEEEEEEE~~B~~HHHHHHHHHHHHHTT~~HHHHHHH~~TTS~~TTSS~B~HHHHHHHHHHHHSGGGTT~~S~EEEESTT~S~~~~~~~~~~TT~EEEESS~SSHHHHHHHHHHHHTT~EEEEEESS~~SSS~TTTEEE~~TTSHHHHHHHHHHHHHHTSS~SEEE~~~~~~~~SS~GGG~~HHHHHHHHHHHTHHHHHHHHHHS~~~~SS~EEEEEE~~GGGTS~~HHHHHHHHHHHHHHHHHHH~~TTTGGGTEEEEEEEE~~B~~HHHHHHHHHHHHHHT~~HHHHHHH~~TTS~~TTSS~B~HHHHHHHHHHHHSGGGTT~~S~EEEESTT~S~~~~~~SS~~TT~EEEESS~SSHHHHHHHHHHHHTT~EEEEEESS~~TTS~GGGEEE~~TTSHHHHHHHHHHHHHHHSS~SEEE~~~~~~~~SS~GGG~~HHHHHHHHHHHTHHHHHHHHHHTT~~~SS~EEEEEE~~GGGTS~~HHHHHHHHHHHHHHHHHHH~~TTTGGGTEEEEEEEE~~B~~HHHHHHHHHHHHHHT~~HHHHHHH~~TTS~~TTSS~B~HHHHHHHHHHHHSGGGTT~~S~EEEESTT~S~~~~~~SS~~TT~EEEESSTTSHHHHHHHHHHHHTT~EEEEEESS~~TTS~GGGEEE~~TTSHHHHHHHHHHHHHHHSS~SEEE~~~~~~~~SS~GGG~~HHHHHHHHHHHTHHHHHHHHHHS~~~~SS~EEEEEE~~GGGTS~~HHHHHHHHHHHHHHHHHHH~~TTTGGGTEEEEEEEE~~B~~HHHHHHHHHHHHHHT~~HHHHHHH~~TTS~~TTSS~B~HHHHHHHHHHHHSGGGTT~~S~EEEESTT~S~~~

S I E F L N L R G K R A L I T A G T K G A G A A T V S L F L E L G A Q V L T T A R A R P E G L P E E L F V E A D L T T K E G C A I V A E A T R Q R L G G V D V I V H L G G S S A A G G G F S A L S D D D W Y N E L S L N L F A A V R L D R Q L V P D V A R G S G V V V H V T S I Q R V L P L P E S T T A Y A A A K A A L S T Y S K A S K E V S P K G V R V V R V S P G W I E T E A S V R L A E R L A K Q A G T D L E G G K K I I D G L G G I P L G R P A K P E E V A N L I A F L A S D R A A S I T G A E Y T I D G G T V P T A S I E F L N L R G K R A L I T A G T K G A G A A T V S L F L E L G A Q V L T T A R A R P E G L P E E L F V E A D L T T K E G C A I V A E A T R Q R L G G V D V I V H L G G S S A A G G G F S A L S D D D W Y N E L S L N L F A A V R L D R Q L V P D V A R G S G V V V H V T S I Q R V L P L P E S T T A Y A A A K A A L S T Y S K A S K E V S P K G V R V V R V S P G W I E T E A S V R L A E R L A K Q A G T D L E G G K K I I D G L G G I P L G R P A K P E E V A N L I A F L A S D R A A S I T G A E Y T I D G G T V P T A S I E F L N L R G K R A L I T A G T K G A G A A T V S L F L E L G A Q V L T T A R A R P E G L P E E L F V E A D L T T K E G C A I V A E A T R Q R L G G V D V I V H L G G S S A A G G G F S A L S D D D W Y N E L S L N L F A A V R L D R Q L V P D V A R G S G V V V H V T S I Q R V L P L P E S T T A Y A A A K A A L S T Y S K A S K E V S P K G V R V V R V S P G W I E T E A S V R L A E R L A K Q A G T D L E G G K K I I D G L G G I P L G R P A K P E E V A N L I A F L A S D R A A S I T G A E Y T I D G G T V P T A S I E F L N L R G K R A L I T A G T K G A G A A T V S L F L E L G A Q V L T T A R A R P E G L P E E L F V E A D L T T K E G C A I V A E A T R Q R L G G V D V I V H L G G S S A A G G G F S A L S D D D W Y N E L S L N L F A A V R L D R Q L V P D V A R G S G V V V H V T S I Q R V L P L P E S T T A Y A A A K A A L S T Y S K A S K E V S P K G V R V V R V S P G W I E T E A S V R L A E R L A K Q A G T D L E G G K K I I D G L G G I P L G R P A K P E E V A N L I A F L A S D R A A S I T G A E Y T I D G G T V P T A

AH

UNSTRUCTURED

3EIS

PTIGMIVPPAAGLVPADGARLYPDLPFIASGLGLEGYDAVIESVVDHARRLQKQGAAVVSLMGTSLSFYRGAAFNAALTVAMREATGLPCTTMSTAVLNGLRALGVRRVALATAYIDDVNERLAAFLAEESLVPTGRSLGIMARVDTATLVDLCVRAFEAAPDSDGILLSGGLLTLDAIPEVERRLGVPVVSSSPAGFWDAVRLAGGGAKARPGYGRLFDESSTPTIGMIVPPAAGLVPADGARLYPDLPFIASGLGLGSVTPEGYDAVIESVVDHARRLQKQGAAVVSLMGTSLSFYRGAAFNAALTVAMREATGLPCTTMSTAVLNGLRALGVRRVALATAYIDDVNERLAAFLAEESLVPTGRSLGITGVEAMARVDTATLVDLCVRAFEAAPDSDGILLSGGLLTLDAIPEVERRLGVPVVSSSPAGFWDAVRLAGGGAKARPGYGRLFDSTPTIGMIVPPAAGLVPADGARLYPDLPFIASGLGLGSVTPEGYDAVIESVVDHARRLQKQGAAVVSLMGTSLSFYRGAAFNAALTVAMREATGLPCTTMSTAVLNGLRALGVRRVALATAYIDDVNERLAAFLAEESLVPTGRSLGITGVEAMARVDTATLVDLCVRAFEAAPDSDGILLSGGLLTLDAIPEVERRLGVPVVSSSPAGFWDAVRLAGGGAKARPGYGRLFDESASTPTIGMIVPPAAGLVPADGARLYPDLPFIASGLGLGSVTPEGYDAVIESVVDHARRLQKQGAAVVSLMGTSLSFYRGAAFNAALTVAMREATGLPCTTMSTAVLNGLRALGVRRVALATAYIDDVNERLAAFLAEESLVPTGRSLGITGVEAMARVDTATLVDLCVRAFEAAPDSDGILLSGGLLTLDAIPEVERRLGVPVVSSSPAGFWDAVRLAGGGAKARPGYGRLFDES

~~EEEEESSTT~~~~THHHHH~TTS~EEEEE~~~~~HHHHHHHHHHHHHHHHHHT~SEEEE~~HHHHHTT~HHHHHHHHHHHHHHHSS~EEEHHHHHHHHHHHTT~~EEEEEBSS~HHHHHHHHHHHHHTT~EE~~~B~~~~~~~~HHHHHHHHHHHHHH~TT~SEEEE~~~TTHHHHHHHHHHHHSS~EEEHHHHHHHHHHHHH~S~~~~~SSS~GGGG~~~~~EEEEEESSTT~~~~HHHHHH~TTS~EEEEE~~~~~~~TT~HHHHHHHHHHHHHHHHHTTEEEEEE~~HHHHHTT~HHHHHHHHHHHHHHHSS~EEEHHHHHHHHHHHTT~~EEEEEBSS~HHHHHHHHHHHHHTT~EE~~~B~~~GGGGTT~B~~HHHHHHHHHHHHHHSTT~SEEEE~~BS~~TTHHHHHHHHHSS~EEEHHHHHHHHHHHHH~S~~~~~TTS~SS~~~~~~EEEEESSTT~~~~THHHHH~TTS~EEEEE~~TTTSS~SSHHHHHHHHHHHHHHHHHTT~SEEEE~~HHHHHTT~HHHHHHHHHHHHHHHSS~EEEHHHHHHHHHHHTT~~EEEEEBSS~HHHHHHHHHHHHHTT~EE~~~B~~~~~HHHHHT~~HHHHHHHHHHHHHHS~S~SEEEE~~~~~~TTHHHHHHHHHSS~EEEHHHHHHHHHHHHH~S~~~~~SSS~HHHHH~~~~~~EEEEE~GGGTTHHHHHHTT~TT~~EEEEE~GGGT~~~~SHHHHHHHHHHHHHHHHHTT~SEEEE~S~GGGTTT~HHHHHHHHHHHHHHHSS~EEEHHHHHHHHHHHHT~~EEEEEBS~~HHHHHHHHHHHHHTT~EE~~~B~~~~~HHHHTT~~HHHHHHHHHHHHHTSTT~SEEEE~~~S~~TTHHHHHHHHHSS~EEEHHHHHHHHHHHHH~~~~~~~SSS~HHHHT~

P T I G M I V P P A A G L V P A D G A R L Y P D L P F I A S G L G L E G Y D A V I E S V V D H A R R L Q K Q G A A V V S L M G T S L S F Y R G A A F N A A L T V A M R E A T G L P C T T M S T A V L N G L R A L G V R R V A L A T A Y I D D V N E R L A A F L A E E S L V P T G R S L G I M A R V D T A T L V D L C V R A F E A A P D S D G I L L S G G L L T L D A I P E V E R R L G V P V V S S S P A G F W D A V R L A G G G A K A R P G Y G R L F D E S S T P T I G M I V P P A A G L V P A D G A R L Y P D L P F I A S G L G L G S V T P E G Y D A V I E S V V D H A R R L Q K Q G A A V V S L M G T S L S F Y R G A A F N A A L T V A M R E A T G L P C T T M S T A V L N G L R A L G V R R V A L A T A Y I D D V N E R L A A F L A E E S L V P T G R S L G I T G V E A M A R V D T A T L V D L C V R A F E A A P D S D G I L L S G G L L T L D A I P E V E R R L G V P V V S S S P A G F W D A V R L A G G G A K A R P G Y G R L F D S T P T I G M I V P P A A G L V P A D G A R L Y P D L P F I A S G L G L G S V T P E G Y D A V I E S V V D H A R R L Q K Q G A A V V S L M G T S L S F Y R G A A F N A A L T V A M R E A T G L P C T T M S T A V L N G L R A L G V R R V A L A T A Y I D D V N E R L A A F L A E E S L V P T G R S L G I T G V E A M A R V D T A T L V D L C V R A F E A A P D S D G I L L S G G L L T L D A I P E V E R R L G V P V V S S S P A G F W D A V R L A G G G A K A R P G Y G R L F D E S A S T P T I G M I V P P A A G L V P A D G A R L Y P D L P F I A S G L G L G S V T P E G Y D A V I E S V V D H A R R L Q K Q G A A V V S L M G T S L S F Y R G A A F N A A L T V A M R E A T G L P C T T M S T A V L N G L R A L G V R R V A L A T A Y I D D V N E R L A A F L A E E S L V P T G R S L G I T G V E A M A R V D T A T L V D L C V R A F E A A P D S D G I L L S G G L L T L D A I P E V E R R L G V P V V S S S P A G F W D A V R L A G G G A K A R P G Y G R L F D E S

AH

UNSTRUCTURED

5E0S

YILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLSYILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLSAQTAYILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLSYILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLSYILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLSAQYILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLSYILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLMRSNSQGLSLTDSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIITRSLTDSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIITRSLTDSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIITRSLTDSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIITRSLTDSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIITRSLTDSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIITRSLTDSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIITRAHVNGEYILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLSAYILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLSAQTAYILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLSAYILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLSYILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLSAQYILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLSYILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLSSLTDSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIITRAHVNGSLTDSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIITRAHVSLTDSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIITRSLTDSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIITRSLTDSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIITRSLTDSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIITRSLTDSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIITRAHVNGE

~~~~~EEE~~SS~~EEE~HHHHHHHTTEEEE~S~B~HHHHHHHHHHHHHHHHH~TTS~EEEEEEE~~B~HHHHHHHHHHHHHSSS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~~~~S~EEEEHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHSS~EEEEHHHHHHTTS~SEE~~~~~~~~~~~~EEE~~SS~~EEE~HHHHHHHTTEEEE~S~B~HHHHHHHHHHHHHHHHH~TTS~EEEEEEE~~B~HHHHHHHHHHHHHSSS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~~~~S~EEEEHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHSS~EEEEHHHHHHHTS~SEE~~~~~TTT~~~~~~~~EEE~~SS~~EEE~HHHHHHHTTEEEE~S~B~HHHHHHHHHHHHHHHHH~TTS~EEEEEEE~~B~HHHHHHHHHHHHHSSS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~~~~S~EEEEHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHSS~EEEEHHHHHHHTS~SEE~~~~~~~~~~~~EEE~~SS~~EEE~HHHHHHHTTEEEE~S~B~HHHHHHHHHHHHHHHHH~TTS~EEEEEEE~~B~HHHHHHHHHHHHHSSS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~~~~S~EEEEHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHSS~EEEEHHHHHHHTS~SEE~~~~~~~~~~~~EEE~~SS~~EEE~HHHHHHHTTEEEE~S~B~HHHHHHHHHHHHHHHHH~TTS~EEEEEEE~~B~HHHHHHHHHHHHHSSS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~~~~S~EEEEHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHSS~EEEEHHHHHHTTS~SEE~~~~~SS~~~~~~~EEE~~SS~~EEE~HHHHHHHTTEEEE~S~B~HHHHHHHHHHHHHHHHH~TTS~EEEEEEE~~B~HHHHHHHHHHHHHSSS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~~~~S~EEEEHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHSS~EEEEHHHHHHHTS~SEE~~~~~~~~~~~~EEE~~SS~~EEE~HHHHHHHTTEEEE~S~B~HHHHHHHHHHHHHHHHH~TTS~EEEEEEE~~B~HHHHHHHHHHHHHSSS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~~~~S~EEEEHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHSS~EEEEHHHHHHHTS~SEE~~~~~~~~~~~SSSSHHHHHHHHHHHTTEEEE~S~B~HHHHHHHHHHHHHHHHH~SSS~EEEEEEE~~B~HHHHHHHHHHHHH~SS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~EEEE~SSHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHTS~EEEEHHHHHHHTS~SEE~~~~HHHHHHHHHHTTTEEEE~S~B~HHHHHHHHHHHHHHHHH~SSS~EEEEEEE~~B~HHHHHHHHHHHHH~SS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~EEEE~S~HHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHTS~EEEEHHHHHHHTS~SEE~~~~HHHHHHHHHHTTTEEEE~S~B~HHHHHHHHHHHHHHHHH~SSS~EEEEEEE~~B~HHHHHHHHHHHHH~SS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~EEEE~SSHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHTS~EEEEHHHHHHHTS~SEE~~~~HHHHHHHHHHTTTEEEE~S~B~HHHHHHHHHHHHHHHHH~SSS~EEEEEEE~~B~HHHHHHHHHHHHH~SS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~EEEE~SSHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHTS~EEEEHHHHHHHTS~SEE~~~~HHHHHHHHHHTTTEEEE~S~B~HHHHHHHHHHHHHHHHH~SSS~EEEEEEE~~B~HHHHHHHHHHHHH~SS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~EEEE~SSHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHTS~EEEEHHHHHHHTS~SEE~~~~HHHHHHHHHHTTTEEEE~S~B~HHHHHHHHHHHHHHHHH~SSS~EEEEEEE~~B~HHHHHHHHHHHHH~SS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~EEEE~S~HHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHTS~EEEEHHHHHHHTS~SEE~~~~HHHHHHHHHHTTTEEEE~S~B~HHHHHHHHHHHHHHHHH~SSS~EEEEEEE~~B~HHHHHHHHHHHHH~SS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~EEEE~SSHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHTS~EEEEHHHHHHHTS~SEE~~SSS~~~~~~~~~EEE~~SS~~EEE~HHHHHHHTTEEEE~S~B~HHHHHHHHHHHHHHHHH~TTS~EEEEEEE~~B~HHHHHHHHHHHHHSSS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~~~~S~EEEEHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHSS~EEEEHHHHHHTTS~SEE~~~~~TT~~~~~~EEE~~SS~~EEE~HHHHHHHTTEEEE~S~B~HHHHHHHHHHHHHHHHH~TTS~EEEEEEE~~B~HHHHHHHHHHHHHSSS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~~~~S~EEEEHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHSS~EEEEHHHHHHTTS~SEE~~~~~SS~~~~~~~~~EEE~~SS~~EEE~HHHHHHHTTEEEE~S~B~HHHHHHHHHHHHHHHHH~TTS~EEEEEEE~~B~HHHHHHHHHHHHHSSS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~~~~S~EEEEHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHSS~EEEEHHHHHHHTS~SEE~~~~~TT~~~~~~EEE~~SS~~EEE~HHHHHHHTTEEEE~S~B~HHHHHHHHHHHHHHHHH~TTS~EEEEEEE~~B~HHHHHHHHHHHHHSSS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~~~~S~EEEEHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHSS~EEEEHHHHHHHTS~SEE~~~~~~~~~~~~EEE~~SS~~EEE~HHHHHHHTTEEEE~S~B~HHHHHHHHHHHHHHHHH~TTS~EEEEEEE~~B~HHHHHHHHHHHHHSSS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~~~~S~EEEEHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHSS~EEEEHHHHHHHTS~SEE~~~~~SS~~~~~~~EEE~~SS~~EEE~HHHHHHHTTEEEE~S~B~HHHHHHHHHHHHHHHHH~TTS~EEEEEEE~~B~HHHHHHHHHHHHHSSS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~~~~S~EEEEHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHSS~EEEEHHHHHHHTS~SEE~~~~~~~~~~~~EEE~~SS~~EEE~HHHHHHHTTEEEE~S~B~HHHHHHHHHHHHHHHHH~TTS~EEEEEEE~~B~HHHHHHHHHHHHHSSS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~~~~S~EEEEHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHSS~EEEEHHHHHHHTS~SEE~~~~~~~~HHHHHHHHHHTTTEEEE~S~B~HHHHHHHHHHHHHHHHH~SSS~EEEEEEE~~B~HHHHHHHHHHHHH~SS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~EEEE~SSHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHTS~EEEEHHHHHHHTS~SEE~~SSS~~~~HHHHHHHHHHTTTEEEE~S~B~HHHHHHHHHHHHHHHHH~SSS~EEEEEEE~~B~HHHHHHHHHHHHH~SS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~EEEE~SSHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHTS~EEEEHHHHHHHTS~SEE~~SS~~~HHHHHHHHHHTTTEEEE~S~B~HHHHHHHHHHHHHHHHH~SSS~EEEEEEE~~B~HHHHHHHHHHHHH~SS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~EEEE~SSHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHTTS~EEEEHHHHHHHTS~SEE~~~~HHHHHHHHHHTTTEEEE~S~B~HHHHHHHHHHHHHHHHH~SSS~EEEEEEE~~B~HHHHHHHHHHHHHSSS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~EEEE~SSHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHTS~EEEEHHHHHHHTS~SEE~~~~HHHHHHHHHHTTTEEEE~S~B~HHHHHHHHHHHHHHHHH~SSS~EEEEEEE~~B~HHHHHHHHHHHHHSSS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~EEEE~SSHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHTS~EEEEHHHHHHHTS~SEE~~~~HHHHHHHHHHHTTEEEE~S~B~HHHHHHHHHHHHHHHHH~SSS~EEEEEEE~~B~HHHHHHHHHHHHT~SS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~EEEE~SSHHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHTTS~EEEEHHHHHHHTS~SEE~~~~HHHHHHHHHHTTTEEEE~S~B~HHHHHHHHHHHHHHHHH~SSS~EEEEEEE~~B~HHHHHHHHHHHHH~SS~EEEEEEEEEETHHHHHHHTS~TT~EEE~TT~EEEE~~~EEEE~S~HHHHHHHHHHHHHHHHHHHHHHHHHH~~~HHHHHHHHTS~EEEEHHHHHHHTS~SEE~~TTT~~~~

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L A A G T P G K R M A L P N A R V L I H Q P S L S G V I Q G Q F S D L E I Q A A E I E R M R T L M E T T L A R H T G K D A G V I R K D T D R D K I L T A E E A K D Y G I I D T V L E Y R K L S Y I L P S F I E H S S F G V K E S N P Y N K L F E E R I I F L G V Q V D D A S A N D I M A Q L L V L E S L D P D R D I T M Y I N S P G G G F T S L M A I Y D T M Q Y V R A D I Q T V C L G Q A A S A A A V L L A A G T P G K R M A L P N A R V L I H Q P S L S G V I Q G Q F S D L E I Q A A E I E R M R T L M E T T L A R H T G K D A G V I R K D T D R D K I L T A E E A K D Y G I I D T V L E Y R K L S Y I L P S F I E H S S F G V K E S N P Y N K L F E E R I I F L G V Q V D D A S A N D I M A Q L L V L E S L D P D R D I T M Y I N S P G G G F T S L M A I Y D T M Q Y V R A D I Q T V C L G Q A A S A A A V L L A A G T P G K R M A L P N A R V L I H Q P S L S G V I Q G Q F S D L E I Q A A E I E R M R T L M E T T L A R H T G K D A G V I R K D T D R D K I L T A E E A K D Y G I I D T V L E Y R K L S A Q Y I L P S F I E H S S F G V K E S N P Y N K L F E E R I I F L G V Q V D D A S A N D I M A Q L L V L E S L D P D R D I T M Y I N S P G G G F T S L M A I Y D T M Q Y V R A D I Q T V C L G Q A A S A A A V L L A A G T P G K R M A L P N A R V L I H Q P S L S G V I Q G Q F S D L E I Q A A E I E R M R T L M E T T L A R H T G K D A G V I R K D T D R D K I L T A E E A K D Y G I I D T V L E Y R K L S Y I L P S F I E H S S F G V K E S N P Y N K L F E E R I I F L G V Q V D D A S A N D I M A Q L L V L E S L D P D R D I T M Y I N S P G G G F T S L M A I Y D T M Q Y V R A D I Q T V C L G Q A A S A A A V L L A A G T P G K R M A L P N A R V L I H Q P S L S G V I Q G Q F S D L E I Q A A E I E R M R T L M E T T L A R H T G K D A G V I R K D T D R D K I L T A E E A K D Y G I I D T V L E Y R K L M R S N S Q G L S L T D S V Y E R L L S E R I I F L G S E V N D E I A N R L C A Q I L L L A A E D A S K D I S L Y I N S P G G S I S A G M A I Y D T M V L A P C D I A T Y A M G M A A S M G E F L L A A G T K G K R Y A L P H A R I L M H Q P L G G V T G S A A D I A I Q A E Q F A V I K K E M F R L N A E F T G Q P I E R I E A D S D R D R W F T A A E A L E Y G F V D H I I T R S L T D S V Y E R L L S E R I I F L G S E V N D E I A N R L C A Q I L L L A A E D A S K D I S L Y I N S P G G S I S A G M A I Y D T M V L A P C D I A T Y A M G M A A S M G E F L L A A G T K G K R Y A L P H A R I L M H Q P L G G V T G S A A D I A I Q A E Q F A V I K K E M F R L N A E F T G Q P I E R I E A D S D R D R W F T A A E A L E Y G F V D H I I T R S L T D S V Y E R L L S E R I I F L G S E V N D E I A N R L C A Q I L L L A A E D A S K D I S L Y I N S P G G S I S A G M A I Y D T M V L A P C D I A T Y A M G M A A S M G E F L L A A G T K G K R Y A L P H A R I L M H Q P L G G V T G S A A D I A I Q A E Q F A V I K K E M F R L N A E F T G Q P I E R I E A D S D R D R W F T A A E A L E Y G F V D H I I T R S L T D S V Y E R L L S E R I I F L G S E V N D E I A N R L C A Q I L L L A A E D A S K D I S L Y I N S P G G S I S A G M A I Y D T M V L A P C D I A T Y A M G M A A S M G E F L L A A G T K G K R Y A L P H A R I L M H Q P L G G V T G S A A D I A I Q A E Q F A V I K K E M F R L N A E F T G Q P I E R I E A D S D R D R W F T A A E A L E Y G F V D H I I T R S L T D S V Y E R L L S E R I I F L G S E V N D E I A N R L C A Q I L L L A A E D A S K D I S L Y I N S P G G S I S A G M A I Y D T M V L A P C D I A T Y A M G M A A S M G E F L L A A G T K G K R Y A L P H A R I L M H Q P L G G V T G S A A D I A I Q A E Q F A V I K K E M F R L N A E F T G Q P I E R I E A D S D R D R W F T A A E A L E Y G F V D H I I T R S L T D S V Y E R L L S E R I I F L G S E V N D E I A N R L C A Q I L L L A A E D A S K D I S L Y I N S P G G S I S A G M A I Y D T M V L A P C D I A T Y A M G M A A S M G E F L L A A G T K G K R Y A L P H A R I L M H Q P L G G V T G S A A D I A I Q A E Q F A V I K K E M F R L N A E F T G Q P I E R I E A D S D R D R W F T A A E A L E Y G F V D H I I T R S L T D S V Y E R L L S E R I I F L G S E V N D E I A N R L C A Q I L L L A A E D A S K D I S L Y I N S P G G S I S A G M A I Y D T M V L A P C D I A T Y A M G M A A S M G E F L L A A G T K G K R Y A L P H A R I L M H Q P L G G V T G S A A D I A I Q A E Q F A V I K K E M F R L N A E F T G Q P I E R I E A D S D R D R W F T A A E A L E Y G F V D H I I T R A H V N G E Y I L P S F I E H S S F G V K E S N P Y N K L F E E R I I F L G V Q V D D A S A N D I M A Q L L V L E S L D P D R D I T M Y I N S P G G G F T S L M A I Y D T M Q Y V R A D I Q T V C L G Q A A S A A A V L L A A G T P G K R M A L P N A R V L I H Q P S L S G V I Q G Q F S D L E I Q A A E I E R M R T L M E T T L A R H T G K D A G V I R K D T D R D K I L T A E E A K D Y G I I D T V L E Y R K L S A Y I L P S F I E H S S F G V K E S N P Y N K L F E E R I I F L G V Q V D D A S A N D I M A Q L L V L E S L D P D R D I T M Y I N S P G G G F T S L M A I Y D T M Q Y V R A D I Q T V C L G Q A A S A A A V L L A A G T P G K R M A L P N A R V L I H Q P S L S G V I Q G Q F S D L E I Q A A E I E R M R T L M E T T L A R H T G K D A G V I R K D T D R D K I L T A E E A K D Y G I I D T V L E Y R K L S A Q T A Y I L P S F I E H S S F G V K E S N P Y N K L F E E R I I F L G V Q V D D A S A N D I M A Q L L V L E S L D P D R D I T M Y I N S P G G G F T S L M A I Y D T M Q Y V R A D I Q T V C L G Q A A S A A A V L L A A G T P G K R M A L P N A R V L I H Q P S L S G V I Q G Q F S D L E I Q A A E I E R M R T L M E T T L A R H T G K D A G V I R K D T D R D K I L T A E E A K D Y G I I D T V L E Y R K L S A Y I L P S F I E H S S F G V K E S N P Y N K L F E E R I I F L G V Q V D D A S A N D I M A Q L L V L E S L D P D R D I T M Y I N S P G G G F T S L M A I Y D T M Q Y V R A D I Q T V C L G Q A A S A A A V L L A A G T P G K R M A L P N A R V L I H Q P S L S G V I Q G Q F S D L E I Q A A E I E R M R T L M E T T L A R H T G K D A G V I R K D T D R D K I L T A E E A K D Y G I I D T V L E Y R K L S Y I L P S F I E H S S F G V K E S N P Y N K L F E E R I I F L G V Q V D D A S A N D I M A Q L L V L E S L D P D R D I T M Y I N S P G G G F T S L M A I Y D T M Q Y V R A D I Q T V C L G Q A A S A A A V L L A A G T P G K R M A L P N A R V L I H Q P S L S G V I Q G Q F S D L E I Q A A E I E R M R T L M E T T L A R H T G K D A G V I R K D T D R D K I L T A E E A K D Y G I I D T V L E Y R K L S A Q Y I L P S F I E H S S F G V K E S N P Y N K L F E E R I I F L G V Q V D D A S A N D I M A Q L L V L E S L D P D R D I T M Y I N S P G G G F T S L M A I Y D T M Q Y V R A D I Q T V C L G Q A A S A A A V L L A A G T P G K R M A L P N A R V L I H Q P S L S G V I Q G Q F S D L E I Q A A E I E R M R T L M E T T L A R H T G K D A G V I R K D T D R D K I L T A E E A K D Y G I I D T V L E Y R K L S Y I L P S F I E H S S F G V K E S N P Y N K L F E E R I I F L G V Q V D D A S A N D I M A Q L L V L E S L D P D R D I T M Y I N S P G G G F T S L M A I Y D T M Q Y V R A D I Q T V C L G Q A A S A A A V L L A A G T P G K R M A L P N A R V L I H Q P S L S G V I Q G Q F S D L E I Q A A E I E R M R T L M E T T L A R H T G K D A G V I R K D T D R D K I L T A E E A K D Y G I I D T V L E Y R K L S S L T D S V Y E R L L S E R I I F L G S E V N D E I A N R L C A Q I L L L A A E D A S K D I S L Y I N S P G G S I S A G M A I Y D T M V L A P C D I A T Y A M G M A A S M G E F L L A A G T K G K R Y A L P H A R I L M H Q P L G G V T G S A A D I A I Q A E Q F A V I K K E M F R L N A E F T G Q P I E R I E A D S D R D R W F T A A E A L E Y G F V D H I I T R A H V N G S L T D S V Y E R L L S E R I I F L G S E V N D E I A N R L C A Q I L L L A A E D A S K D I S L Y I N S P G G S I S A G M A I Y D T M V L A P C D I A T Y A M G M A A S M G E F L L A A G T K G K R Y A L P H A R I L M H Q P L G G V T G S A A D I A I Q A E Q F A V I K K E M F R L N A E F T G Q P I E R I E A D S D R D R W F T A A E A L E Y G F V D H I I T R A H V S L T D S V Y E R L L S E R I I F L G S E V N D E I A N R L C A Q I L L L A A E D A S K D I S L Y I N S P G G S I S A G M A I Y D T M V L A P C D I A T Y A M G M A A S M G E F L L A A G T K G K R Y A L P H A R I L M H Q P L G G V T G S A A D I A I Q A E Q F A V I K K E M F R L N A E F T G Q P I E R I E A D S D R D R W F T A A E A L E Y G F V D H I I T R S L T D S V Y E R L L S E R I I F L G S E V N D E I A N R L C A Q I L L L A A E D A S K D I S L Y I N S P G G S I S A G M A I Y D T M V L A P C D I A T Y A M G M A A S M G E F L L A A G T K G K R Y A L P H A R I L M H Q P L G G V T G S A A D I A I Q A E Q F A V I K K E M F R L N A E F T G Q P I E R I E A D S D R D R W F T A A E A L E Y G F V D H I I T R S L T D S V Y E R L L S E R I I F L G S E V N D E I A N R L C A Q I L L L A A E D A S K D I S L Y I N S P G G S I S A G M A I Y D T M V L A P C D I A T Y A M G M A A S M G E F L L A A G T K G K R Y A L P H A R I L M H Q P L G G V T G S A A D I A I Q A E Q F A V I K K E M F R L N A E F T G Q P I E R I E A D S D R D R W F T A A E A L E Y G F V D H I I T R S L T D S V Y E R L L S E R I I F L G S E V N D E I A N R L C A Q I L L L A A E D A S K D I S L Y I N S P G G S I S A G M A I Y D T M V L A P C D I A T Y A M G M A A S M G E F L L A A G T K G K R Y A L P H A R I L M H Q P L G G V T G S A A D I A I Q A E Q F A V I K K E M F R L N A E F T G Q P I E R I E A D S D R D R W F T A A E A L E Y G F V D H I I T R S L T D S V Y E R L L S E R I I F L G S E V N D E I A N R L C A Q I L L L A A E D A S K D I S L Y I N S P G G S I S A G M A I Y D T M V L A P C D I A T Y A M G M A A S M G E F L L A A G T K G K R Y A L P H A R I L M H Q P L G G V T G S A A D I A I Q A E Q F A V I K K E M F R L N A E F T G Q P I E R I E A D S D R D R W F T A A E A L E Y G F V D H I I T R A H V N G E

AH

BS

1XZD

RTTRDDLINGNSASCADVIFIYARGSTETGNLGTLGPSIASNLESAFGKDGVWIQGVGGAYRATLGDNALPRGTSSAAIREMLGLFQQANTKCPDATLIAGGYSQGAALAAASIEDLDSAIRDKIAGTVLFGYTKNLQNRGRIPNYPADRTKVFCNTGDLVCTGSLIVAAPHLAYGPDARGPAPEFLIEKVRAVRGC

~~~~BHHHH~~GGG~~SEEEEEE~~TT~STTTTTTHHHHHHHHHHHH~GGGEEEEE~~TT~~~~GGGGGSTTSS~HHHHHHHHHHHHHHHHH~TTSEEEEEEETHHHHHHHHHHHHS~HHHHTTEEEEEEES~TTTTTTTT~~TTS~GGGEEEE~~TT~GGGGT~~~~~GGGG~~HHHHHTHHHHHHHHHHHHH~~~

R T T R D D L I N G N S A S C A D V I F I Y A R G S T E T G N L G T L G P S I A S N L E S A F G K D G V W I Q G V G G A Y R A T L G D N A L P R G T S S A A I R E M L G L F Q Q A N T K C P D A T L I A G G Y S Q G A A L A A A S I E D L D S A I R D K I A G T V L F G Y T K N L Q N R G R I P N Y P A D R T K V F C N T G D L V C T G S L I V A A P H L A Y G P D A R G P A P E F L I E K V R A V R G C

AH

UNSTRUCTURED

1K99

MKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKK

~~~~~SSSSS~~~S~~HHHHHHHHHHHHHHTT~ETS~SHHHHHHHHHHHHHS~STTHHHHHHHHHHHHHHHHHHHGGGGG~~~~~S~~~~~

M K K L K K H P D F P K K P L T P Y F R F F M E K R A K Y A K L H P E M S N L D L T K I L S K K Y K E L P E K K K M K Y I Q D F Q R E K Q E F E R N L A R F R E D H P D L I Q N A K K

AH

UNSTRUCTURED

4TN7

RTFDLEEKLQTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKDFQKESLSMDMEQVHLTHFELEGLRCLVDKLESLPLHKKCVPTGIEDEDALIADVKILLEELASSDPKLALTGVPIVQWPRTFDLEEKLQTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKDFQKESLSMDMEQVHLTHFELEGLRCLVDKLESLPLHKKCVPTGIEDEDALIADVKILLEELASSDPKLALTGVPIVQWPAPATGGVKPAPATGGVKP

~~S~HHHHHH~S~~B~~~~EE~~GGG~SHHHHHHH~S~S~EEESS~TTT~~B~~~TT~~HHHHHHHH~TT~EEEEEETTT~~EEEEEHHHHHHHHTS~TTT~SS~EEEEEEE~TTSTTGGG~B~~HHHHHH~HHHHTS~HHHHTT~~~~S~BTTT~~S~~~S~EEEEE~TT~EEEEE~~GGG~EEEEEEEES~EEEEEE~~~HHHHHHHHHHHHH~~TTS~~GGGGSS~~EEEEE~TT~EEEE~TT~EEEEE~SS~EEEEEEEE~~TT~HHHHHHHHHHHHHTT~~GGGS~TTHHHHHHHHHHHHHHHHH~~~~B~HHHHHHHHHHHT~~~~~~HHHHHHHHHHHHHHHSS~HHHH~~~TTBS~HHHHHHHHHHHHHHTTT~~HHHH~~SS~S~~~~~~S~HHHHHH~S~~B~~~~EE~~GGG~SHHHHHHH~S~S~EEESS~TTT~~B~~~TT~~HHHHHHHH~TT~EEEEEETTTTEEEEEEHHHHHHHHHS~TTT~SS~EEEEEEE~TTSTTGGG~B~~HHHHHH~HHHHTS~HHHHTT~~~~S~BTTT~~S~~~S~EEEEE~TT~EEEEE~~GGG~EEEEEEEES~EEEEEE~~~HHHHHHHHHHHHHSGGGS~~TTTSSS~~EEEEE~TT~EEEE~TT~EEEEE~SS~EEEEEEEE~~TT~HHHHHHHHHHHHHTT~~GGGS~TTHHHHHHHHHHHHHHHHH~~~~B~HHHHHHHHHHHT~~~~~~HHHHHHHHHHHHHHHTS~HHHH~~~TTBS~HHHHHHHHHHHHHHTTT~~HHHH~~SS~S~~~~~~~B~~~~~~~~B~~~~~

R T F D L E E K L Q T N K Y N A N F V T F M E G K D F N V E Y I Q R G G L R D P L I F K N S D G L G I K M P D P D F T V N D V K M C V G S R R M V D V M D V N T Q K G I E M T M A Q W T R Y Y E T P E E E R E K L Y N V I S L E F S H T R L E N M V Q R P S T V D F I D W V D N M W P R H L K E S Q T E S T N A I L E M Q Y P K V Q K Y C L M S V R G C Y T D F H V D F G G T S V W Y H I H Q G G K V F W L I P P T A H N L E L Y E N W L L S G K Q G D I F L G D R V S D C Q R I E L K Q G Y T F V I P S G W I H A V Y T P T D T L V F G G N F L H S F N I P M Q L K I Y S I E D R T R V P N K F R Y P F Y Y E M C W Y V L E R Y V Y C I T N R S H L T K D F Q K E S L S M D M E Q V H L T H F E L E G L R C L V D K L E S L P L H K K C V P T G I E D E D A L I A D V K I L L E E L A S S D P K L A L T G V P I V Q W P R T F D L E E K L Q T N K Y N A N F V T F M E G K D F N V E Y I Q R G G L R D P L I F K N S D G L G I K M P D P D F T V N D V K M C V G S R R M V D V M D V N T Q K G I E M T M A Q W T R Y Y E T P E E E R E K L Y N V I S L E F S H T R L E N M V Q R P S T V D F I D W V D N M W P R H L K E S Q T E S T N A I L E M Q Y P K V Q K Y C L M S V R G C Y T D F H V D F G G T S V W Y H I H Q G G K V F W L I P P T A H N L E L Y E N W L L S G K Q G D I F L G D R V S D C Q R I E L K Q G Y T F V I P S G W I H A V Y T P T D T L V F G G N F L H S F N I P M Q L K I Y S I E D R T R V P N K F R Y P F Y Y E M C W Y V L E R Y V Y C I T N R S H L T K D F Q K E S L S M D M E Q V H L T H F E L E G L R C L V D K L E S L P L H K K C V P T G I E D E D A L I A D V K I L L E E L A S S D P K L A L T G V P I V Q W P A P A T G G V K P A P A T G G V K P

AH

UNSTRUCTURED

1J97

EKKKKLILFFDSTLVNNETIDEIAREAGVEEEVKKITKEAMEGKLNFEQSLRKRVSLLKDLPIEKVEKAIKRITPTEGAEETIKELKNRGYVVAVVSGGFDIAVNKIKEKLGLDYAFANRLIVKDGKLTGDVEGEVLKENAKGEILEKIAKIEGINLEDTVAVGDGANDISMFKKAGLKIAFCAKPILKEKADICIEKRDLREILKYIKKKKKLILFFDSTLVNNETIDEIAREAGVEEEVKKITKEAMEGKLNFEQSLRKRVSLLKDLPIEKVEKAIKRITPTEGAEETIKELKNRGYVVAVVSGGFDIAVNKIKEKLGLDYAFANRLIVKDGKLTGDVEGEVLKENAKGEILEKIAKIEGINLEDTVAVGDGANDISMFKKAGLKIAFCAKPILKEKADICIEKRDLREILKYIK

~~~~~EEE~~TTTTBSS~HHHHHHHHTT~HHHHHHHHHHHHTTSS~HHHHHHHHHHTTTT~BHHHHHHHHHT~~B~TTHHHHHHHHHHTT~EEEEEEEEEHHHHHHHHHHHT~SEEEEEEEEEETTEEEEEEE~SS~STTHHHHHHHHHHHHHT~~GGGEEEEESSGGGHHHHHH~SEEEEES~~HHHHTT~SEEE~SS~GGGGGGG~~~~~EEEE~~TTTTBSS~HHHHHHHHTT~HHHHHHHHHHHHTTSS~HHHHHHHHHHTTTT~BHHHHHHHHHT~~B~TTHHHHHHHHHHTTEEEEEEEEEEHHHHHHHHHHHT~SEEEEEEEEEETTEEEEEEE~SS~STTHHHHHHHHHHHHHT~~GGGEEEEE~SGGGHHHHHH~SEEEEES~~HHHHTT~SEEE~SS~GGGGGGG~~

E K K K K L I L F F D S T L V N N E T I D E I A R E A G V E E E V K K I T K E A M E G K L N F E Q S L R K R V S L L K D L P I E K V E K A I K R I T P T E G A E E T I K E L K N R G Y V V A V V S G G F D I A V N K I K E K L G L D Y A F A N R L I V K D G K L T G D V E G E V L K E N A K G E I L E K I A K I E G I N L E D T V A V G D G A N D I S M F K K A G L K I A F C A K P I L K E K A D I C I E K R D L R E I L K Y I K K K K K L I L F F D S T L V N N E T I D E I A R E A G V E E E V K K I T K E A M E G K L N F E Q S L R K R V S L L K D L P I E K V E K A I K R I T P T E G A E E T I K E L K N R G Y V V A V V S G G F D I A V N K I K E K L G L D Y A F A N R L I V K D G K L T G D V E G E V L K E N A K G E I L E K I A K I E G I N L E D T V A V G D G A N D I S M F K K A G L K I A F C A K P I L K E K A D I C I E K R D L R E I L K Y I K

AH

BS

4HXW

GLEAVRKRPGMYIGSTSGEGLHHLVWEIVDNSIDEALAGFAKSIQVIIEPDDSITVIDDGRGIPVGIQAKTGRPAVETVFTVLVGSSVVNALSTSLDVRVYKDGKVYYQEYRRGAVVDDLKVIEETDRHGTTVHFIPDPEIFTETTVYDFDKLATRVRELAFLNRGLHISIEDRREGQEDKKEYHYEGLEH

~HHHHHH~THHHHS~SSHHHHHHHHHHHHHHHHHHHHTT~~~EEEEEE~TTS~EEEEE~SS~~~~SB~TTTSSBHHHHHHH~~~~HHHHHHTEEEEEEEEEETTEEEEEEEETTEE~S~~EEEEE~S~~EEEEEEEE~TTT~~S~~~~~HHHHHHHHHHHHHHTTT~EEEEEE~STT~~EEEEEE~~~TT~

G L E A V R K R P G M Y I G S T S G E G L H H L V W E I V D N S I D E A L A G F A K S I Q V I I E P D D S I T V I D D G R G I P V G I Q A K T G R P A V E T V F T V L V G S S V V N A L S T S L D V R V Y K D G K V Y Y Q E Y R R G A V V D D L K V I E E T D R H G T T V H F I P D P E I F T E T T V Y D F D K L A T R V R E L A F L N R G L H I S I E D R R E G Q E D K K E Y H Y E G L E H

AH

BS

3SJC

TVEPNLHSLITSTTHKWIFVGGKGGVGKTTSSCSIAIQMALSQPNKQFLLISTDPAHNLSDAFGEKFGKDARKVTGMNNLSCMEIDPSAALGSIPGIDEALSFMEVMKHIKRQEQGEGETFDTVIFDTAPTGHTLRFLQLPNTLSLNELKANVETIRQQFTDPDLTTFVCVCISEFLSLYETERLIQELISYDMDVNSIIVNQLLFAECKRCQARWKMQKKYLDQIDELYEDFHVVKMPLCAGEIRGLNNLTKFSQFLNKEYNPITDGKVIYELEDTVEPNLHSLITSTTHKWIFVGGKGGVGKTTSSCSIAIQMALSQPNKQFLLISTDPAHNLSDAFGEKFGKDARKVTGMNNLSCMEIDPSAAGSIPGIDEALSFMEVMKHIKRQEQGEGETFDTVIFDTAPTGHTLRFLQLPNTLSGKLNELKANVETIRQQFTDPDLTTFVCVCISEFLSLYETERLIQELISYDMDVNSIIVNQLLFAECKRCQARWKMQKKYLDQIDELYEDFHVVKMPLCAGEIRGLNNLTKFSQFLNKEYNPITDGKVIYELEDLSKKYLAKVKERHELKEFNNSISAQDNYAKWTKNNRKLDSLDKEINNLKDEIQSLSKKYLAKVKERHELKEFNNSISAQDNYAKWTKNNRKLDSLDKEINNLKDEIQSTVEPNLHSLITSTTHKWIFVGGKGGVGKTTSSCSIAIQMALSQPNKQFLLISTDPAHNLSDAFGEKFGKDARKVTGMNNLSCMEIDPSAALGSIPGIDEALSFMEVMKHIKRQEQGEGETFDTVIFDTAPTGHTLRFLQLPNTLSKGKLNELKANVETIRQQFTDPDLTTFVCVCISEFLSLYETERLIQELISYDMDVNSIIVNQLLFAECKRCQARWKMQKKYLDQIDELYEDFHVVKMPLCAGEIRGLNNLTKFSQFLNKEYNPITDGKVIYELEDVEPNLHSLITSTTHKWIFVGGKGGVGKTTSSCSIAIQMALSQPNKQFLLISTDPAHNLSDAFGEKFGKDARKVTGMNNLSCMEIDPSAALGSIPGIDEALSFMEVMKHIKRQEQGEGETFDTVIFDTAPTGHTLRFLQLPNTSGKLNELKANVETIRQQFTDPDLTTFVCVCISEFLSLYETERLIQELISYDMDVNSIIVNQLLFAECKRCQARWKMQKKYLDQIDELYEDFHVVKMPLCAGEIRGLNNLTKFSQFLNKEYNPITDGKVIYELEDLSKKYLAKVKERHELKEFNNSISAQDNYAKWTKNNRKLDSLDKEINNLKDEIQSLSKKYLAKVKERHELKEFNNSISAQDNYAKWTKNNRKLDSLDKEINNLKDEIQS

~~~SSSHHHHT~SS~SEEEEE~~SSSSHHHHHHHHHHHHHHH~TTS~EEEEE~~TT~HHHHHHTS~~~SS~EE~TT~SSEEEEE~~HHHH~~~~TTHHHHHHHHHHHHHHHHHHHTTSS~~SEEEEE~BTTB~~GGGGGHHHHH~~HHHHHHHHHHHHHHH~TTTEEEEEEEESSHHHHHHHHHHHHHHHHTT~EEEEEEEEEE~~~~~TTHHHHHHHHHHHHHHHHTT~TTSEEEEEE~~SS~~~SHHHHHHHHGGGTTT~~TTTTTHHHHHT~~~~~SSSHHHHT~SS~~EEEEE~~SS~SHHHHHHHHHHHHHTT~TTS~EEEEE~~TT~HHHHHHTS~~~SS~EE~TT~SSEEEEE~~TTT~~~~SSHHHHHHHHHHHHHHHHHHHTTS~~~SEEEEE~~TT~~GGGGGGHHHH~~HHHHHHHHHHHHHHHHHH~TTTEEEEEEEESSHHHHHHHHHHHHHHHHTT~EEEEEEEEEE~~~~~~SHHHHHHHHHHHHHHHHTT~TTSEEEEEE~~SS~~~SHHHHHHHHGGGTTT~~HHHHHHHHHHH~~~HHHHHHHHHHHHHHHHHHHTS~TTTSHHHHHHHHHHHHHHHHHHHHHHHHHT~~HHHHHHHHHHHHHHHHHHHTS~TTTSHHHHHHHHHHHHHHHHHHHHHHHHHT~~~~SSSHHHHT~SS~~EEEEE~~SS~SHHHHHHHHHHHHHTT~TTS~EEEEE~~TT~HHHHHHTS~~~SS~EE~TT~SSEEEEE~~HHHH~~~~SSHHHHHHHHHHHHHHHHHHHTTS~~~SEEEEE~~TT~~GGGGGGHHHHT~~~HHHHHHHHHHHHHHHHS~TTTEEEEEEEESSHHHHHHHHHHHHHHHHTT~B~~EEEEEEE~~~~~~SHHHHHHHHHHHHHHHHTT~TTSEEEEEE~~SS~~~SHHHHHHHHGGGTTT~~HHHHHHHHHHH~~~~SSSHHHHT~SS~~EEEEE~~SS~SHHHHHHHHHHHHHTT~TTS~EEEEE~~TT~HHHHHHTS~~~SS~EE~TT~SSEEEEE~~HHHH~~~~SSHHHHHHHHHHHHHHHHHHHTTS~~~SEEEEE~~TT~~GGGGGGTTT~~HHHHHHHHHHHHHHHHHH~TTTEEEEEEEESSHHHHHHHHHHHHHHHHTT~B~~EEEEEEE~~~~~~SHHHHHHHHHHHHHHHHTT~TTSEEEEEE~~SS~~~SHHHHHHHHGGGTTT~~HHHHHHHHHHH~~~HHHHHHHHHHHHHHHHHHHTS~TTTSHHHHHHHHHHHHHHHHHHHHHHHHHT~~HHHHHHHHHHHHHHHHHHHTS~TTTSHHHHHHHHHHHHHHHHHHHHHHHHHT~

T V E P N L H S L I T S T T H K W I F V G G K G G V G K T T S S C S I A I Q M A L S Q P N K Q F L L I S T D P A H N L S D A F G E K F G K D A R K V T G M N N L S C M E I D P S A A L G S I P G I D E A L S F M E V M K H I K R Q E Q G E G E T F D T V I F D T A P T G H T L R F L Q L P N T L S L N E L K A N V E T I R Q Q F T D P D L T T F V C V C I S E F L S L Y E T E R L I Q E L I S Y D M D V N S I I V N Q L L F A E C K R C Q A R W K M Q K K Y L D Q I D E L Y E D F H V V K M P L C A G E I R G L N N L T K F S Q F L N K E Y N P I T D G K V I Y E L E D T V E P N L H S L I T S T T H K W I F V G G K G G V G K T T S S C S I A I Q M A L S Q P N K Q F L L I S T D P A H N L S D A F G E K F G K D A R K V T G M N N L S C M E I D P S A A G S I P G I D E A L S F M E V M K H I K R Q E Q G E G E T F D T V I F D T A P T G H T L R F L Q L P N T L S G K L N E L K A N V E T I R Q Q F T D P D L T T F V C V C I S E F L S L Y E T E R L I Q E L I S Y D M D V N S I I V N Q L L F A E C K R C Q A R W K M Q K K Y L D Q I D E L Y E D F H V V K M P L C A G E I R G L N N L T K F S Q F L N K E Y N P I T D G K V I Y E L E D L S K K Y L A K V K E R H E L K E F N N S I S A Q D N Y A K W T K N N R K L D S L D K E I N N L K D E I Q S L S K K Y L A K V K E R H E L K E F N N S I S A Q D N Y A K W T K N N R K L D S L D K E I N N L K D E I Q S T V E P N L H S L I T S T T H K W I F V G G K G G V G K T T S S C S I A I Q M A L S Q P N K Q F L L I S T D P A H N L S D A F G E K F G K D A R K V T G M N N L S C M E I D P S A A L G S I P G I D E A L S F M E V M K H I K R Q E Q G E G E T F D T V I F D T A P T G H T L R F L Q L P N T L S K G K L N E L K A N V E T I R Q Q F T D P D L T T F V C V C I S E F L S L Y E T E R L I Q E L I S Y D M D V N S I I V N Q L L F A E C K R C Q A R W K M Q K K Y L D Q I D E L Y E D F H V V K M P L C A G E I R G L N N L T K F S Q F L N K E Y N P I T D G K V I Y E L E D V E P N L H S L I T S T T H K W I F V G G K G G V G K T T S S C S I A I Q M A L S Q P N K Q F L L I S T D P A H N L S D A F G E K F G K D A R K V T G M N N L S C M E I D P S A A L G S I P G I D E A L S F M E V M K H I K R Q E Q G E G E T F D T V I F D T A P T G H T L R F L Q L P N T S G K L N E L K A N V E T I R Q Q F T D P D L T T F V C V C I S E F L S L Y E T E R L I Q E L I S Y D M D V N S I I V N Q L L F A E C K R C Q A R W K M Q K K Y L D Q I D E L Y E D F H V V K M P L C A G E I R G L N N L T K F S Q F L N K E Y N P I T D G K V I Y E L E D L S K K Y L A K V K E R H E L K E F N N S I S A Q D N Y A K W T K N N R K L D S L D K E I N N L K D E I Q S L S K K Y L A K V K E R H E L K E F N N S I S A Q D N Y A K W T K N N R K L D S L D K E I N N L K D E I Q S

AH

UNSTRUCTURED

4Q1N

LTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALARLTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR

~~~~SB~EEEEEEEETTTEEEEEEEETTTTEEEEEEEETT~~~EEEEBTTS~TTSHHHHSS~~B~GGG~SS~EEEEEEEEEEETTEEEEEEEEEEEEEETTEEEEEEEEEEEE~~HHHHTT~SSSEEEE~S~GGG~GGG~~~HHHHHHHTT~BSSSEEEEEE~~~~~~~EEEEESS~~GGGEEEEEEEEE~SSTTS~EEEE~EEEETTEEEESTT~EEEEE~TT~SSEEE~HHHHHHHHHHHT~EE~SS~EEEEGGGGGG~~~EEEEETTEEEEE~HHHHB~~~~~~TTSEEEBSEEE~~~~TTT~S~EEE~HHHHHHEEEEEETTTTEEEEEEE~~~~~SB~EEEEEEEETTTEEEEEEEETTTTEEEEEEEETT~~~EEEEBTTS~TTSTHHHHS~~B~GGG~SS~EEEEEEEEEEETTEEEEEEEEEEEEEETTEEEEEEEEEEEE~~HHHHTT~SSSEEEE~S~GGG~GGG~~~HHHHHHHTT~BSSSEEEEEE~~~~~~~EEEEESS~~GGGEEEEEEEEE~SSTTS~EEEE~EEEETTEEEE~TT~EEEEE~TT~SSEEE~HHHHHHHHHHHT~EE~SSSEEEEGGGGGGS~~EEEEETTEEEEE~HHHHB~~S~~~TTSEEEBSEEE~~~~TTT~S~EEE~HHHHHHEEEEEETTTTEEEEEEE~

L T L G N T T S S V I L T N Y M D T Q Y Y G E I G I G T P P Q T F K V V F D T G S S N V W V P S S K C S R L Y T A C V Y H K L F D A S D S S S Y K H N G T E L T L R Y S T G T V S G F L S Q D I I T V G G I T V T Q M F G E V T E M P A L P F M L A E F D G V V G M G F I E Q A I G R V T P I F D N I I S Q G V L K E D V F S F Y Y N R D Q S L G G Q I V L G G S D P Q H Y E G N F H Y I N L I K T G V W Q I Q M K G V S V G S S T L L C E D G C L A L V D T G A S Y I S G S T S S I E K L M E A L G A K K R L F D Y V V K C N E G P T L P D I S F H L G G K E Y T L T S A D Y V F Q E S Y S S K K L C T L A I H A M D I P P P T G P T W A L G A T F I R K F Y T E F D R R N N R I G F A L A R L T L G N T T S S V I L T N Y M D T Q Y Y G E I G I G T P P Q T F K V V F D T G S S N V W V P S S K C S R L Y T A C V Y H K L F D A S D S S S Y K H N G T E L T L R Y S T G T V S G F L S Q D I I T V G G I T V T Q M F G E V T E M P A L P F M L A E F D G V V G M G F I E Q A I G R V T P I F D N I I S Q G V L K E D V F S F Y Y N R D Q S L G G Q I V L G G S D P Q H Y E G N F H Y I N L I K T G V W Q I Q M K G V S V G S S T L L C E D G C L A L V D T G A S Y I S G S T S S I E K L M E A L G A K K R L F D Y V V K C N E G P T L P D I S F H L G G K E Y T L T S A D Y V F Q E S Y S S K K L C T L A I H A M D I P P P T G P T W A L G A T F I R K F Y T E F D R R N N R I G F A L A R

BS

UNSTRUCTURED

1IZB

GIVEQCCTSICSLYQLENYCNFVNQHLCGSHLVQALYLVCGERGFFYTPKTGIVEQCCTSICSLYQLENYCNFVNQHLCGSHLVQALYLVCGERGFFYTPKT

~HHHHHHHS~B~HHHHGGGB~~~~B~~~THHHHHHHHHHHGGG~EEE~~~~~HHHHHTTS~B~HHHHGGGB~~~~B~~~THHHHHHHHHHHGGG~EEE~TT~

G I V E Q C C T S I C S L Y Q L E N Y C N F V N Q H L C G S H L V Q A L Y L V C G E R G F F Y T P K T G I V E Q C C T S I C S L Y Q L E N Y C N F V N Q H L C G S H L V Q A L Y L V C G E R G F F Y T P K T

AH

UNSTRUCTURED

3QWG

TTFAARLNRLFDTVYPPGRGPHTSAEVIAALKAEGITMSAPYLSQLRSGNRTNPSGATMAALANFFRIKAAYFTDDEYYEKLDKELQWLCTMRTTFAARLNRLFDTVYPPGRGPHTSAEVIAALKAEGITMSAPYLSQLRSGNRTNPSGATMAALANFFRIKAAYFTDDEYYEKLDKELQWLC

~~HHHHHHHHHHHSS~TTT~S~~HHHHHHHHHHTT~~~~HHHHHHHHHTSS~~~~HHHHHHHHHHTTS~THHHH~HHHHHHHHHHHHHHHHH~~~HHHHHHHHHHH~S~TTT~~~~HHHHHHHHHHTT~~~~HHHHHHHHTTS~~E~~HHHHHHHHHHHTS~THHHH~HHHHHHHHHHHHHH~

T T F A A R L N R L F D T V Y P P G R G P H T S A E V I A A L K A E G I T M S A P Y L S Q L R S G N R T N P S G A T M A A L A N F F R I K A A Y F T D D E Y Y E K L D K E L Q W L C T M R T T F A A R L N R L F D T V Y P P G R G P H T S A E V I A A L K A E G I T M S A P Y L S Q L R S G N R T N P S G A T M A A L A N F F R I K A A Y F T D D E Y Y E K L D K E L Q W L C

AH

UNSTRUCTURED

1XYU

VVGGLGGYMLGSAMSRPLIHFGNDYEDRYYRENMYRYPNQVYYRPVDHYSNQNNFVHDCVNITVKQHTVTTTTKGENFTETDIKIMERVVEQMCITQYQRESQAYYQRGAS

~~TTSSS~EE~~~~~~~~~~~~SSSHHHHHHTTTTSS~S~~EE~~GGGT~~STHHHHHHHHHHHHHHHHHHHTTT~~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT~~

V V G G L G G Y M L G S A M S R P L I H F G N D Y E D R Y Y R E N M Y R Y P N Q V Y Y R P V D H Y S N Q N N F V H D C V N I T V K Q H T V T T T T K G E N F T E T D I K I M E R V V E Q M C I T Q Y Q R E S Q A Y Y Q R G A S

AH

UNSTRUCTURED

5CQZ

KYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEYESLGFELTVERLVSIGYPQELLSFAYDSTFPTRGLVFDTLYGNLLKVDAYGNLLVCAHGFNFIRGPETREQYPNKFIQRDDTERFYILNTLFNLPETYLLACLVDFFTNCPRYTSCETGFKDGDLFMSYRSMFQDVRDAVDWVHYKGSLKEKTVENLEKYVVKDGKLPLLLSRMKEVGKVFLATNSDYKYTDKIMTYLFDFPHGPKPGSSHRPWQSYFDLILVDARKPLFFGEGTVLRQVDTKTGKLKIGTYTGPLQHGIVYSGGSSDTICDLLGAKGKDILYIGDHIFGDKSKKRQGWRTFLVIPELAQELHVWTDKSSLFEELQSLDIFLAELYKHLDSSSNERPDISSIQRRIKKVTHDMDMCYGMMGSLFRSGSRQTLFASQVMRYADLYAASFINLLYYPFSYLFRAAHVLMPHESTVEHTKYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEYESLGFELTVERLVSIGYPQELLSFAYDSTFPTRGLVFDTLYGNLLKVDAYGNLLVCAHGFNFIRGPETREQYPNKFIQRDDTERFYILNTLFNLPETYLLACLVDFFTNCPRYTSCETGFKDGDLFMSYRSMFQDVRDAVDWVHYKGSLKEKTVENLEKYVVKDGKLPLLLSRMKEVGKVFLATNSDYKYTDKIMTYLFDFPHGPKPGSSHRPWQSYFDLILVDARKPLFFGEGTVLRQVDTKTGKLKIHGIVYSGGSSDTICDLLGAKGKDILYIGDHIFGDRQGWRTFLVIPELAQELHVWTDKSSLFEELQSLDIFLAELYKHLDSSSNERPDISSIQRRIKKVTHDMDMCYGMMGSLFRSGSRQTLFASQVMRYADLYAASFINLLYYPFSYLFRAAHVLMPHESTVEH

~~~~~GGG~~EESS~EEGGG~~EEEE~TBTTTB~B~TTHHHHHHHHHHHHHHHHTT~~GGGGG~~~~TTS~~TTEEEETTTTEEEEEBTTSBEEEEEETTEE~~GGGGGGTSGGGB~~TT~TTTEEEE~STTHHHHHHHHHHHHHHHHH~TTSEEETTEEEETTEEEEHHHHHHHHHHHHHHHHHTSSHHHHHHTTHHHHB~~~THHHHHHHHHHTTSEEEEE~SS~HHHHHHHHHHHT~SSSSSSTTS~~~~GGGG~SEEEE~~~TTGGGTT~~~EEEB~TTTSSB~SS~~~S~S~SS~~EEE~~HHHHHHHHT~~GGGEEEEES~~~~~~~SSS~~~EEEEE~TTHHHHHHHHHHTHHHHHHHHHHHHHHHHHTTT~~TT~~~~~~~HHHHHHHHHHHHHHHHHH~TT~~SSEETTEEBHHHHHHHHH~SEEES~GGGGGGS~TT~EE~~~~~~~HHHHTS~~~~~~~~GGG~~EESS~EEGGG~~EEEE~TBTTTB~B~TTHHHHHHHHHHHHHHHHTT~~GGGGG~~~~TTS~~TTEEEETTTTEEEEEBTTSBEEEEEETTEE~~SGGGTTTSGGGB~~TT~TTTEEEE~STTHHHHHHHHHHHHHHHHH~TTSEEETTEEEETTEEEEHHHHHHHHHHHHHHHHHTSSHHHHHHTTHHHHB~~~THHHHHHHHHHTTSEEEEE~SS~HHHHHHHHHHHH~SSSSSSTTS~~~~GGGG~SEEEES~~TTGGGTT~~~EEEB~TTTSSB~~~~~~EEE~~HHHHHHHHT~~GGGEEEEES~~~~~~~~~EEEEE~TTHHHHHHHHHHTHHHHHHHHHHHHHHHHHTTT~~TT~~~~~~~HHHHHHHHHHHHHHHHTT~SS~~SSEETTEEBHHHHHHHHH~SEEES~GGGGGGS~TT~EE~~~~~~~HHHHT~~~

K Y R R E A Y H R V F V N R S L A M E K I K C F G F D M D Y T L A V Y K S P E Y E S L G F E L T V E R L V S I G Y P Q E L L S F A Y D S T F P T R G L V F D T L Y G N L L K V D A Y G N L L V C A H G F N F I R G P E T R E Q Y P N K F I Q R D D T E R F Y I L N T L F N L P E T Y L L A C L V D F F T N C P R Y T S C E T G F K D G D L F M S Y R S M F Q D V R D A V D W V H Y K G S L K E K T V E N L E K Y V V K D G K L P L L L S R M K E V G K V F L A T N S D Y K Y T D K I M T Y L F D F P H G P K P G S S H R P W Q S Y F D L I L V D A R K P L F F G E G T V L R Q V D T K T G K L K I G T Y T G P L Q H G I V Y S G G S S D T I C D L L G A K G K D I L Y I G D H I F G D K S K K R Q G W R T F L V I P E L A Q E L H V W T D K S S L F E E L Q S L D I F L A E L Y K H L D S S S N E R P D I S S I Q R R I K K V T H D M D M C Y G M M G S L F R S G S R Q T L F A S Q V M R Y A D L Y A A S F I N L L Y Y P F S Y L F R A A H V L M P H E S T V E H T K Y R R E A Y H R V F V N R S L A M E K I K C F G F D M D Y T L A V Y K S P E Y E S L G F E L T V E R L V S I G Y P Q E L L S F A Y D S T F P T R G L V F D T L Y G N L L K V D A Y G N L L V C A H G F N F I R G P E T R E Q Y P N K F I Q R D D T E R F Y I L N T L F N L P E T Y L L A C L V D F F T N C P R Y T S C E T G F K D G D L F M S Y R S M F Q D V R D A V D W V H Y K G S L K E K T V E N L E K Y V V K D G K L P L L L S R M K E V G K V F L A T N S D Y K Y T D K I M T Y L F D F P H G P K P G S S H R P W Q S Y F D L I L V D A R K P L F F G E G T V L R Q V D T K T G K L K I H G I V Y S G G S S D T I C D L L G A K G K D I L Y I G D H I F G D R Q G W R T F L V I P E L A Q E L H V W T D K S S L F E E L Q S L D I F L A E L Y K H L D S S S N E R P D I S S I Q R R I K K V T H D M D M C Y G M M G S L F R S G S R Q T L F A S Q V M R Y A D L Y A A S F I N L L Y Y P F S Y L F R A A H V L M P H E S T V E H

AH

UNSTRUCTURED

5.00E+75

FYTSDEALEAATAPLYNRAWFDYNQRSIVPIGSGRANDMYSPWNYPQFVTFQVTALDENLSGAWSGFYSVVTMANSVINAVETQTQSVSEAAKTKAIAEARLMRACAYFYMLRIWGPVILIEDNQKLVDNPVRPLNREEDVFQFIINDLNYAVDNLSEQSDKGRATSWAAKGILAKVYLARSGWNNGGTRDEGDLELARQYASDVCENSGLDLMTNYEDLFKYKNNNNQESLLAMQWVPLGEWYECNTLLSDLAFSTEVTGGVNCWSSYNGSIDMLQQYELADTLRRNATFFTKGSYYSYICIKDGGYTYKGTASPIKKGVPGGPDDDNDGKVKQMNSPLNTYILRLADVYLTYAEACLGNNSTLSDGRGLYFFNRVRERAKINKKSSITLDDIIRERRVEFGMEYSNWYDMVTWFRYLPDKMLNYFNNQWRGYRTDAIIKDEDGKLHFGKYDTDGTTFLEGPEYYTAPEFTINIEAEDIFLPYPESDVIQNPLLNEPPVPYTFNE

~B~SHHHHHHHHGGGGTGGGHHHHTTTHHHHHTTTTTSEE~SSSSHHHHHT~~~TT~HHHHHHHHHHHHHHHHHHHHHHHHHHSB~~~~HHHHHHHHHHHHHHHHHHHHHHHTTTSSB~~~S~HHHHHH~~~~~~B~HHHHHHHHHHHHHHHHHHS~SS~STTS~~HHHHHHHHHHHHHHHHTTTSTT~~~HHHHHHHHHHHHHHHHHS~~~~~SSGGGGGSGGGTT~TTEEEEE~~~TTS~GGGSBTTHHHH~~~GGGTTT~~~~~~~EE~HHHHHHS~TT~HHHHHHHB~~TT~EETTSSGGGT~EE~~SSS~~B~TT~~~~TTTTSTT~~BTTBB~~~EEEEEHHHHHHHHHHHHHTTSS~B~SSHHHHHHHHHHHHTT~~~~SSB~HHHHHHHHHHHHTTTT~HHHHHHHHHHHSHHHHHHHHHTS~TT~B~SEEEE~TT~~EEEEEE~TTSSSEEESGGGSB~~S~~~~~~HHHHS~~~~HHHHHH~GGGGS~~B~~~~~~

F Y T S D E A L E A A T A P L Y N R A W F D Y N Q R S I V P I G S G R A N D M Y S P W N Y P Q F V T F Q V T A L D E N L S G A W S G F Y S V V T M A N S V I N A V E T Q T Q S V S E A A K T K A I A E A R L M R A C A Y F Y M L R I W G P V I L I E D N Q K L V D N P V R P L N R E E D V F Q F I I N D L N Y A V D N L S E Q S D K G R A T S W A A K G I L A K V Y L A R S G W N N G G T R D E G D L E L A R Q Y A S D V C E N S G L D L M T N Y E D L F K Y K N N N N Q E S L L A M Q W V P L G E W Y E C N T L L S D L A F S T E V T G G V N C W S S Y N G S I D M L Q Q Y E L A D T L R R N A T F F T K G S Y Y S Y I C I K D G G Y T Y K G T A S P I K K G V P G G P D D D N D G K V K Q M N S P L N T Y I L R L A D V Y L T Y A E A C L G N N S T L S D G R G L Y F F N R V R E R A K I N K K S S I T L D D I I R E R R V E F G M E Y S N W Y D M V T W F R Y L P D K M L N Y F N N Q W R G Y R T D A I I K D E D G K L H F G K Y D T D G T T F L E G P E Y Y T A P E F T I N I E A E D I F L P Y P E S D V I Q N P L L N E P P V P Y T F N E

AH

UNSTRUCTURED

4DAL

DTQLLIGSRFEAGTEAEEHILNPRTGAGIIDLAEASHAQIDAAVDAAERAFVGWSQTTPAERSNALLKIADAIEKEADEFAALEALNCGKPINAVKNDELPAIIDCWRFFAGAVRNLHAPAAGEYLPGHTSIRRDPIGIVGSIAPWNYPLAWKLAPAIGGGNTVVFKPSEQTPLTALKLARLIADILPEGVVNVITGRGETVGNALINHPKVGVSITGDIATGKKVLAAAAKTVKRTHLELGGKAPVIVYGDADLEAVVNGIRTFGYYNAGQDCTAACRIYAEAGIYEKLVADLTSAVSTIRYNLDDDTENEIGPLISRRQRDRVASFVERAADQKHIEITTGGRTGSDEGFFFQPTVVAGATQEDEIVRREVFGPVVSVTRFTGKDDAVAWANDSDYGLASSVWTKDISKARAASRLQYGCTWINTHFLTNEPHGGIKQSGYGKDSVYALEDYTAVRHIINHGDTQLLIGSRFEAGTEAEEHILNPRTGAGIIDLAEASHAQIDAAVDAAERAFVGWSQTTPAERSNALLKIADAIEKEADEFAALEALNCGKPINAVKNDELPAIIDCWRFFAGAVRNLHAPAAGEYLPGHTSIRRDPIGIVGSIAPWNYPLAWKLAPAIGGGNTVVFKPSEQTPLTALKLARLIADILPEGVVNVITGRGETVGNALINHPKVGVSITGDIATGKKVLAAAAKTVKRTHLELGGKAPVIVYGDADLEAVVNGIRTFGYYNAGQDCTAACRIYAEAGIYEKLVADLTSAVSTIRYNLDDDTENEIGPLISRRQRDRVASFVERAADQKHIEITTGGRTGSDEGFFFQPTVVAGATQEDEIVRREVFGPVVSVTRFTGKDDAVAWANDSDYGLASSVWTKDISKARAASRLQYGCTWINTHFLTNEPHGGIKQSGYGKDSVYALEDYTAVRHIINHGDTQLLIGSRFEAGTEAEEHILNPRTGAGIIDLAEASHAQIDAAVDAAERAFVGWSQTTPAERSNALLKIADAIEKEADEFAALEALNCGKPINAVKNDELPAIIDCWRFFAGAVRNLHAPAAGEYLPGHTSIRRDPIGIVGSIAPWNYPLAWKLAPAIGGGNTVVFKPSEQTPLTALKLARLIADILPEGVVNVITGRGETVGNALINHPKVGVSITGDIATGKKVLAAAAKTVKRTHLELGGKAPVIVYGDADLEAVVNGIRTFGYYNAGQDCTAACRIYAEAGIYEKLVADLTSAVSTIRYNLDDDTENEIGPLISRRQRDRVASFVERAADQKHIEITTGGRTGSDEGFFFQPTVVAGATQEDEIVRREVFGPVVSVTRFTGKDDAVAWANDSDYGLASSVWTKDISKARAASRLQYGCTWINTHFLTNEPHGGIKQSGYGKDSVYALEDYTAVRHIINHGDTQLLIGSRFEAGTEAEEHILNPRTGAGIIDLAEASHAQIDAAVDAAERAFVGWSQTTPAERSNALLKIADAIEKEADEFAALEALNCGKPINAVKNDELPAIIDCWRFFAGAVRNLHAPAAGEYLPGHTSIRRDPIGIVGSIAPWNYPLAWKLAPAIGGGNTVVFKPSEQTPLTALKLARLIADILPEGVVNVITGRGETVGNALINHPKVGVSITGDIATGKKVLAAAAKTVKRTHLELGGKAPVIVYGDADLEAVVNGIRTFGYYNAGQDCTAACRIYAEAGIYEKLVADLTSAVSTIRYNLDDDTENEIGPLISRRQRDRVASFVERAADQKHIEITTGGRTGSDEGFFFQPTVVAGATQEDEIVRREVFGPVVSVTRFTGKDDAVAWANDSDYGLASSVWTKDISKARAASRLQYGCTWINTHFLTNEPHGGIKQSGYGKDSVYALEDYTAVRHIINHGDTQLLIGSRFEAGTEAEEHILNPRTGAGIIDLAEASHAQIDAAVDAAERAFVGWSQTTPAERSNALLKIADAIEKEADEFAALEALNCGKPINAVKNDELPAIIDCWRFFAGAVRNLHAPAAGEYLPGHTSIRRDPIGIVGSIAPWNYPLAWKLAPAIGGGNTVVFKPSEQTPLTALKLARLIADILPEGVVNVITGRGETVGNALINHPKVGVSITGDIATGKKVLAAAAKTVKRTHLELGGKAPVIVYGDADLEAVVNGIRTFGYYNAGQDCTAACRIYAEAGIYEKLVADLTSAVSTIRYNLDDDTENEIGPLISRRQRDRVASFVERAADQKHIEITTGGRTGSDEGFFFQPTVVAGATQEDEIVRREVFGPVVSVTRFTGKDDAVAWANDSDYGLASSVWTKDISKARAASRLQYGCTWINTHFLTNEPHGGIKQSGYGKDSVYALEDYTAVRHIINHGDTQLLIGSRFEAGTEAEEHILNPRTGAGIIDLAEASHAQIDAAVDAAERAFVGWSQTTPAERSNALLKIADAIEKEADEFAALEALNCGKPINAVKNDELPAIIDCWRFFAGAVRNLHAPAAGEYLPGHTSIRRDPIGIVGSIAPWNYPLAWKLAPAIGGGNTVVFKPSEQTPLTALKLARLIADILPEGVVNVITGRGETVGNALINHPKVGVSITGDIATGKKVLAAAAKTVKRTHLELGGKAPVIVYGDADLEAVVNGIRTFGYYNAGQDCTAACRIYAEAGIYEKLVADLTSAVSTIRYNLDDDTENEIGPLISRRQRDRVASFVERAADQKHIEITTGGRTGSDEGFFFQPTVVAGATQEDEIVRREVFGPVVSVTRFTGKDDAVAWANDSDYGLASSVWTKDISKARAASRLQYGCTWINTHFLTNEPHGGIKQSGYGKDSVYALEDYTAVRHIINHGDTQLLIGSRFEAGTEAEEHILNPRTGAGIIDLAEASHAQIDAAVDAAERAFVGWSQTTPAERSNALLKIADAIEKEADEFAALEALNCGKPINAVKNDELPAIIDCWRFFAGAVRNLHAPAAGEYLPGHTSIRRDPIGIVGSIAPWNYPLAWKLAPAIGGGNTVVFKPSEQTPLTALKLARLIADILPEGVVNVITGRGETVGNALINHPKVGVSITGDIATGKKVLAAAAKTVKRTHLELGGKAPVIVYGDADLEAVVNGIRTFGYYNAGQDCTAACRIYAEAGIYEKLVADLTSAVSTIRYNLDDDTENEIGPLISRRQRDRVASFVERAADQKHIEITTGGRTGSDEGFFFQPTVVAGATQEDEIVRREVFGPVVSVTRFTGKDDAVAWANDSDYGLASSVWTKDISKARAASRLQYGCTWINTHFLTNEPHGGIKQSGYGKDSVYALEDYTAVRHIINHDTQLLIGSRFEAGTEAEEHILNPRTGAGIIDLAEASHAQIDAAVDAAERAFVGWSQTTPAERSNALLKIADAIEKEADEFAALEALNCGKPINAVKNDELPAIIDCWRFFAGAVRNLHAPAAGEYLPGHTSIRRDPIGIVGSIAPWNYPLAWKLAPAIGGGNTVVFKPSEQTPLTALKLARLIADILPEGVVNVITGRGETVGNALINHPKVGVSITGDIATGKKVLAAAAKTVKRTHLELGGKAPVIVYGDADLEAVVNGIRTFGYYNAGQDCTAACRIYAEAGIYEKLVADLTSAVSTIRYNLDDDTENEIGPLISRRQRDRVASFVERAADQKHIEITTGGRTGSDEGFFFQPTVVAGATQEDEIVRREVFGPVVSVTRFTGKDDAVAWANDSDYGLASSVWTKDISKARAASRLQYGCTWINTHFLTNEPHGGIKQSGYGKDSVYALEDYTAVRHIINHG

~~~EEETTEEE~~~S~EEEEE~TTT~~EEEEEE~~~HHHHHHHHHHHHHHHHHHTTS~HHHHHHHHHHHHHHHHHTHHHHHHHHHHHH~~~HHHHHHTHHHHHHHHHHHHHHHHTT~EEE~BSEEETTEE~~EEE~~~EEEEE~~SSS~~~TTHHHHHHTT~EEEEE~~TT~~HHHHHHHHHHHHHS~TTSEEE~~~~TTTHHHHHHT~TT~~~EEES~HHHHHHHHHHHHHHT~~~EEE~~~~EEEEE~TTS~HHHHHHHHHHHTTGGGG~STT~EEEEEEEHHHHHHHHHHHHHHHTT~~BS~SSGGG~SB~~~SSHHHHHHHHHHHHHHHHSTT~EEEE~~SB~~SSS~~B~~EEEES~~TTSHHHHS~~~SSEEEEEEE~TTS~HHHHHHSSS~~SEEEEE~SBTTT~~HHHH~~SSEEEES~~~~~~~~~~~SGGGEE~~~~HHHHHHTSEEEB~~B~~~~~EEETTEEE~~~S~EEEEE~TTT~~EEEEEE~~~HHHHHHHHHHHHHHHHHHTT~~HHHHHHHHHHHHHHHHHTHHHHHHHHHHHH~~~HHHHHHTHHHHHHHHHHHHHHHHT~~EEE~BSEEETTEE~~EEEE~~EEEEE~~SSS~~~TTTHHHHHTT~EEEEE~~TT~~HHHHHHHHHHHTTS~TTSEEE~~~~TTTHHHHHHT~TT~~~EEES~HHHHHHHHHHHTTTT~~~EEE~~~~~EEEE~TTS~HHHHHHHHHHHTTGGGG~STT~S~EEEEEHHHHHHHHHHHHHHHTT~~~S~SSGGG~S~~~~SSHHHHHHHHHHHHHHHTSTT~EEEE~~SBS~SSS~~B~~EEEES~~TT~HHHHS~~~SSEEEEEEE~TTS~HHHHHHSSS~~S~EEEE~SBTTT~~HHHH~~SSBEEES~~~~~~~~~~~SGGGEE~~~~HHHHHTTEEEEB~~B~~~~~EEETTEEE~~~S~EEEEE~TTT~~EEEEEE~~~HHHHHHHHHHHHHHHHHHTTS~HHHHHHHHHHHHHHHHHTHHHHHHHHHHHH~~~HHHHHHTHHHHHHHHHHHHHHHTT~~EEE~BS~SBTTB~~~EEEE~~EEEEE~~SSS~~~TTHHHHHHTT~EEEEE~~TT~~HHHHHHHHHHHTTS~TTSEEE~~~~TTTHHHHHHT~TT~~~EEES~HHHHHHHHHHHHTTT~~~EEE~~~~EEEEE~TTS~HHHHHHHHHHHTTGGGG~STT~EEEEEEEHHHHHHHHHHHHHHHHT~~~S~SSTTT~S~~~~S~HHHHHHHHHHHHHHHHSTT~EEEE~~SB~~SSSS~B~~EEEES~~TTSHHHHS~~~SSEEEEEEE~TTS~HHHHHHSSS~~SEEEEE~SBTTT~~HHHH~~SSEEEES~~~~~~~~~~~SGGGEE~~~~HHHHHHTEEEEB~~B~~~~~EEETTEEE~~~S~EEEEEETTTTEEEEEEE~~~HHHHHHHHHHHHHHHHHHTTS~HHHHHHHHHHHHHHHHHTHHHHHHHHHHHH~~~HHHHHHTHHHHHHHHHHHHHHHHT~~EEE~BS~SBTTB~~~EEEE~~EEEEE~~SSS~~~TTHHHHHHTT~EEEEE~~TT~~HHHHHHHHHHHTTS~TTSEEE~~~~TTTHHHHHHH~TTB~~EEES~HHHHHHHHHHHHHHT~~~EEE~~~~EEEEE~TTS~HHHHHHHHHHHTTGGGG~STT~EEEEEEEHHHHHHHHHHHHHHHTT~~~S~SSGGG~SS~~~S~HHHHHHHHHHHHHHHTSSS~EEEE~~SB~~SSS~~B~~EEEES~~TTSHHHHS~~~SSEEEEEEE~TTS~HHHHHHSSS~~SEEEEE~SBTTT~~HHHH~~SSEEEES~~~~~~~~~~~SGGG~~~~~~HHHHHHTEEEEB~~B~~~~~EEETTEEE~~~S~EEEEE~TTT~~EEEEEE~~~HHHHHHHHHHHHHHHHHHTT~~HHHHHHHHHHHHHHHHHTHHHHHHHHHHHH~~~HHHHHHTHHHHHHHHHHHHHHHTT~~EEE~BS~SBTTB~~~EEEE~~EEEEE~~SSS~~~TTHHHHHHTT~EEEEE~~TT~~HHHHHHHHHHTTTS~TTSEEE~~~~TTTHHHHHHH~TT~~~EEES~HHHHHHHHHHHTTTT~~~EEE~~~~~EEEE~TTS~HHHHHHHHHHHTTGGGG~STT~~~EEEEEHHHHHHHHHHHHHHHTT~~~S~S~GGG~S~~~~SSHHHHHHHHHHHHHHHTSTT~EEEE~~SB~~SSS~~B~~EEEES~~TTSHHHHS~~~SSEEEEEEE~TTS~HHHHHHSSS~~S~EEEE~SBTTT~~HHHH~~SSBEEES~~~~~~~~~~~SGGGEE~~~~HHHHHHTEEEEB~~B~~~~~EEETTEEE~~~S~EEEEE~TTT~~EEEEEE~~~HHHHHHHHHHHHHHHHHHTTS~HHHHHHHHHHHHHHHHHTHHHHHHHHHHHH~~~HHHHHHTHHHHHHHHHHHHHHHHT~~EEE~BS~SBTTB~~~EEEE~~EEEEE~~SSS~~~TTHHHHHHTT~EEEEE~~TT~~HHHHHHHHHHHTTS~TTTEEE~~~~TTTHHHHHHT~TT~~~EEES~HHHHHHHHHHHTTTT~~~EEE~~~~EEEEE~TT~~HHHHHHHHHHHTTGGGG~STT~EEEEEEETTTHHHHHHHHHHHHTT~~BS~S~GGG~SB~~~SSHHHHHHHHHHHHHHHTSSS~EEEE~~SB~~SSS~~B~~EEEES~~TTSHHHHS~~~SSEEEEEEE~TTS~HHHHHHSSS~~SEEEEE~SBTTT~~HHHH~~SSEEEES~~~~~~~~~~~SGGGEE~~~~HHHHHHTEEEEB~~B~~~~~EEETTEEE~~~S~EEEEE~TTT~~EEEEEE~~~HHHHHHHHHHHHHHHHHHTTS~HHHHHHHHHHHHHHHHHTHHHHHHHHHHHH~~~HHHHHHTHHHHHHHHHHHHHHHTT~~EEE~BS~SBTTB~~~EEEE~~EEEEE~~SSS~~~TTHHHHHHTT~EEEEE~~SS~~HHHHHHHHHHHTTS~TTSEEE~~~~TTTHHHHHHH~TT~~~EEES~HHHHHHHHHHHHTTT~~~EEE~~~~~EEEE~TTS~HHHHHHHHHHHTTGGGG~STT~~~EEEEEGGGHHHHHHHHHHHHTT~~BS~SSGGG~SB~~~SSHHHHHHHHHHHHHHHTSTT~EEEE~~SB~~SSS~~B~~EEEES~~TTSHHHHS~~~SSEEEEEEE~TTS~HHHHHHSSS~~SEEEEE~SBTTT~~HHHH~~SSEEEES~~~~~~~~~~~SGGG~S~~~~HHHHHHTEEEEB~~B~~~~EEETTEEE~~~S~EEEEE~TTT~~EEEEEE~~~HHHHHHHHHHHHHHHHHHTTS~HHHHHHHHHHHHHHHHTTHHHHHHHHHHHH~~~HHHHHHTHHHHHHHHHHHHHHHHT~~EEE~BS~SBTTB~~~EEEE~~EEEEE~~SSS~~~TTHHHHHHTT~EEEEE~~TT~~HHHHHHHHHHHTTS~TTSEEE~~~~TTTHHHHHHT~TT~~~EEES~HHHHHHHHHHHHHHT~~~EEE~~~~~EEEE~TTS~HHHHHHHHHHHTTGGGG~~TT~~~EEEEEHHHHHHHHHHHHHHHHT~~BS~SSGGG~SB~~~S~HHHHHHHHHHHHHHHT~TT~EEEE~~SB~~SSS~~B~~EEEES~~TTSHHHHS~~~SSEEEEEEE~TTS~HHHHHHSSS~~SEEEEE~SBTTT~~HHHH~~SSEEEES~~~~~~~~~~~SGGGEE~~~~HHHHHHTEEEEB~~B~~

D T Q L L I G S R F E A G T E A E E H I L N P R T G A G I I D L A E A S H A Q I D A A V D A A E R A F V G W S Q T T P A E R S N A L L K I A D A I E K E A D E F A A L E A L N C G K P I N A V K N D E L P A I I D C W R F F A G A V R N L H A P A A G E Y L P G H T S I R R D P I G I V G S I A P W N Y P L A W K L A P A I G G G N T V V F K P S E Q T P L T A L K L A R L I A D I L P E G V V N V I T G R G E T V G N A L I N H P K V G V S I T G D I A T G K K V L A A A A K T V K R T H L E L G G K A P V I V Y G D A D L E A V V N G I R T F G Y Y N A G Q D C T A A C R I Y A E A G I Y E K L V A D L T S A V S T I R Y N L D D D T E N E I G P L I S R R Q R D R V A S F V E R A A D Q K H I E I T T G G R T G S D E G F F F Q P T V V A G A T Q E D E I V R R E V F G P V V S V T R F T G K D D A V A W A N D S D Y G L A S S V W T K D I S K A R A A S R L Q Y G C T W I N T H F L T N E P H G G I K Q S G Y G K D S V Y A L E D Y T A V R H I I N H G D T Q L L I G S R F E A G T E A E E H I L N P R T G A G I I D L A E A S H A Q I D A A V D A A E R A F V G W S Q T T P A E R S N A L L K I A D A I E K E A D E F A A L E A L N C G K P I N A V K N D E L P A I I D C W R F F A G A V R N L H A P A A G E Y L P G H T S I R R D P I G I V G S I A P W N Y P L A W K L A P A I G G G N T V V F K P S E Q T P L T A L K L A R L I A D I L P E G V V N V I T G R G E T V G N A L I N H P K V G V S I T G D I A T G K K V L A A A A K T V K R T H L E L G G K A P V I V Y G D A D L E A V V N G I R T F G Y Y N A G Q D C T A A C R I Y A E A G I Y E K L V A D L T S A V S T I R Y N L D D D T E N E I G P L I S R R Q R D R V A S F V E R A A D Q K H I E I T T G G R T G S D E G F F F Q P T V V A G A T Q E D E I V R R E V F G P V V S V T R F T G K D D A V A W A N D S D Y G L A S S V W T K D I S K A R A A S R L Q Y G C T W I N T H F L T N E P H G G I K Q S G Y G K D S V Y A L E D Y T A V R H I I N H G D T Q L L I G S R F E A G T E A E E H I L N P R T G A G I I D L A E A S H A Q I D A A V D A A E R A F V G W S Q T T P A E R S N A L L K I A D A I E K E A D E F A A L E A L N C G K P I N A V K N D E L P A I I D C W R F F A G A V R N L H A P A A G E Y L P G H T S I R R D P I G I V G S I A P W N Y P L A W K L A P A I G G G N T V V F K P S E Q T P L T A L K L A R L I A D I L P E G V V N V I T G R G E T V G N A L I N H P K V G V S I T G D I A T G K K V L A A A A K T V K R T H L E L G G K A P V I V Y G D A D L E A V V N G I R T F G Y Y N A G Q D C T A A C R I Y A E A G I Y E K L V A D L T S A V S T I R Y N L D D D T E N E I G P L I S R R Q R D R V A S F V E R A A D Q K H I E I T T G G R T G S D E G F F F Q P T V V A G A T Q E D E I V R R E V F G P V V S V T R F T G K D D A V A W A N D S D Y G L A S S V W T K D I S K A R A A S R L Q Y G C T W I N T H F L T N E P H G G I K Q S G Y G K D S V Y A L E D Y T A V R H I I N H G D T Q L L I G S R F E A G T E A E E H I L N P R T G A G I I D L A E A S H A Q I D A A V D A A E R A F V G W S Q T T P A E R S N A L L K I A D A I E K E A D E F A A L E A L N C G K P I N A V K N D E L P A I I D C W R F F A G A V R N L H A P A A G E Y L P G H T S I R R D P I G I V G S I A P W N Y P L A W K L A P A I G G G N T V V F K P S E Q T P L T A L K L A R L I A D I L P E G V V N V I T G R G E T V G N A L I N H P K V G V S I T G D I A T G K K V L A A A A K T V K R T H L E L G G K A P V I V Y G D A D L E A V V N G I R T F G Y Y N A G Q D C T A A C R I Y A E A G I Y E K L V A D L T S A V S T I R Y N L D D D T E N E I G P L I S R R Q R D R V A S F V E R A A D Q K H I E I T T G G R T G S D E G F F F Q P T V V A G A T Q E D E I V R R E V F G P V V S V T R F T G K D D A V A W A N D S D Y G L A S S V W T K D I S K A R A A S R L Q Y G C T W I N T H F L T N E P H G G I K Q S G Y G K D S V Y A L E D Y T A V R H I I N H G D T Q L L I G S R F E A G T E A E E H I L N P R T G A G I I D L A E A S H A Q I D A A V D A A E R A F V G W S Q T T P A E R S N A L L K I A D A I E K E A D E F A A L E A L N C G K P I N A V K N D E L P A I I D C W R F F A G A V R N L H A P A A G E Y L P G H T S I R R D P I G I V G S I A P W N Y P L A W K L A P A I G G G N T V V F K P S E Q T P L T A L K L A R L I A D I L P E G V V N V I T G R G E T V G N A L I N H P K V G V S I T G D I A T G K K V L A A A A K T V K R T H L E L G G K A P V I V Y G D A D L E A V V N G I R T F G Y Y N A G Q D C T A A C R I Y A E A G I Y E K L V A D L T S A V S T I R Y N L D D D T E N E I G P L I S R R Q R D R V A S F V E R A A D Q K H I E I T T G G R T G S D E G F F F Q P T V V A G A T Q E D E I V R R E V F G P V V S V T R F T G K D D A V A W A N D S D Y G L A S S V W T K D I S K A R A A S R L Q Y G C T W I N T H F L T N E P H G G I K Q S G Y G K D S V Y A L E D Y T A V R H I I N H G D T Q L L I G S R F E A G T E A E E H I L N P R T G A G I I D L A E A S H A Q I D A A V D A A E R A F V G W S Q T T P A E R S N A L L K I A D A I E K E A D E F A A L E A L N C G K P I N A V K N D E L P A I I D C W R F F A G A V R N L H A P A A G E Y L P G H T S I R R D P I G I V G S I A P W N Y P L A W K L A P A I G G G N T V V F K P S E Q T P L T A L K L A R L I A D I L P E G V V N V I T G R G E T V G N A L I N H P K V G V S I T G D I A T G K K V L A A A A K T V K R T H L E L G G K A P V I V Y G D A D L E A V V N G I R T F G Y Y N A G Q D C T A A C R I Y A E A G I Y E K L V A D L T S A V S T I R Y N L D D D T E N E I G P L I S R R Q R D R V A S F V E R A A D Q K H I E I T T G G R T G S D E G F F F Q P T V V A G A T Q E D E I V R R E V F G P V V S V T R F T G K D D A V A W A N D S D Y G L A S S V W T K D I S K A R A A S R L Q Y G C T W I N T H F L T N E P H G G I K Q S G Y G K D S V Y A L E D Y T A V R H I I N H G D T Q L L I G S R F E A G T E A E E H I L N P R T G A G I I D L A E A S H A Q I D A A V D A A E R A F V G W S Q T T P A E R S N A L L K I A D A I E K E A D E F A A L E A L N C G K P I N A V K N D E L P A I I D C W R F F A G A V R N L H A P A A G E Y L P G H T S I R R D P I G I V G S I A P W N Y P L A W K L A P A I G G G N T V V F K P S E Q T P L T A L K L A R L I A D I L P E G V V N V I T G R G E T V G N A L I N H P K V G V S I T G D I A T G K K V L A A A A K T V K R T H L E L G G K A P V I V Y G D A D L E A V V N G I R T F G Y Y N A G Q D C T A A C R I Y A E A G I Y E K L V A D L T S A V S T I R Y N L D D D T E N E I G P L I S R R Q R D R V A S F V E R A A D Q K H I E I T T G G R T G S D E G F F F Q P T V V A G A T Q E D E I V R R E V F G P V V S V T R F T G K D D A V A W A N D S D Y G L A S S V W T K D I S K A R A A S R L Q Y G C T W I N T H F L T N E P H G G I K Q S G Y G K D S V Y A L E D Y T A V R H I I N H D T Q L L I G S R F E A G T E A E E H I L N P R T G A G I I D L A E A S H A Q I D A A V D A A E R A F V G W S Q T T P A E R S N A L L K I A D A I E K E A D E F A A L E A L N C G K P I N A V K N D E L P A I I D C W R F F A G A V R N L H A P A A G E Y L P G H T S I R R D P I G I V G S I A P W N Y P L A W K L A P A I G G G N T V V F K P S E Q T P L T A L K L A R L I A D I L P E G V V N V I T G R G E T V G N A L I N H P K V G V S I T G D I A T G K K V L A A A A K T V K R T H L E L G G K A P V I V Y G D A D L E A V V N G I R T F G Y Y N A G Q D C T A A C R I Y A E A G I Y E K L V A D L T S A V S T I R Y N L D D D T E N E I G P L I S R R Q R D R V A S F V E R A A D Q K H I E I T T G G R T G S D E G F F F Q P T V V A G A T Q E D E I V R R E V F G P V V S V T R F T G K D D A V A W A N D S D Y G L A S S V W T K D I S K A R A A S R L Q Y G C T W I N T H F L T N E P H G G I K Q S G Y G K D S V Y A L E D Y T A V R H I I N H G

AH

UNSTRUCTURED

5PCX

SMSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKWTDTFK

~TT~~E~~~~~TTHHHHHHHHHHHHHHSGGGGGGSS~~~TTTSTTHHHH~SS~~~HHHHHHHHHTT~~~SHHHHHHHHHHHHHHHHHHS~SSSHHHHHHHHHHHHHHHHHHHHH~

S M S V K K P K R D D S K D L A L C S M I L T E M E T H E D A W P F L L P V N L K L V P G Y K K V I K K P M D F S T I R E K L S S G Q Y P N L E T F A L D V R L V F D N C E T F N E D D S D I G R A G H N M R K Y F E K K W T D T F K

AH

UNSTRUCTURED

3JUA

SMRSIASSKLWMLEFSAFLERQQDPDTYNKHLFVHIPYLETVDIRQIYDKFPEKKGGLKELFERGPSNAFFLVKFWADLNTNEGSAFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYLYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASAQHHIYRLVKETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPESMRSIASSKLWMLEFSAFLERQQDPDTYNKHLFVHISQDPYLETVDIRQIYDKFPEKKGGLKELFERGPSNAFFLVKFWADLNTNIDDEGSAFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYLYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKTDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKSMRSIASSKLWMLEFSAFLERQQDPDTYNKHLFVHISQSSPSYSDPYLETVDIRQIYDKFPEKKGGLKELFERGPSNAFFLVKFWADLNTNIDDEGSAFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYLYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASAQHHIYRLVKTDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPSMRSIASSKLWMLEFSAFLERQQDPDTYNKHLFVHISQSDPYLETVDIRQIYDKFPEGGLKELFERGPSNAFFLVKFWADLNTNYGVSSQYESPENMIITCSTKVCVETEYARYENGHYLYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSAQHHIYRLVKVPQTVPMRLRKLPDSFFKP

~~SSSB~SS~EEEEEEEEEEE~SSSEEEEEEEEEE~~~~~EEEGGGTGGGS~~SSSSHHHHHHHS~TTSEEEEEEEE~~~~~~~SEEEEEEEEEEESS~~EEEEEEEEEETTEEEEEEEEEEE~EEETTEEEEEEEEEE~~HHHHHHHHHHHSSS~HHHHHHHHTTEEEEEEEEESSS~~EEEEEEEEEEE~~~~EEEEEEEE~~~TTHHHHHHHHS~SSS~~~~~~~GGGS~~~SGGG~~~~~~SSSB~SS~EEEEEEEEEEEESSSEEEEEEEEEE~~~~~~~EEEEGGGTGGGS~~SSS~HHHHHHHS~GGGEEEEEEEE~~~~~GGGSS~~EEEEEEEEEESS~~EEEEEEEEEETTEEEEEEEEEEE~EE~SSSEEEEE~S~~~~HHHHHHHHHHTTSS~HHHHHHHHHTEEEEEEEEESSS~~EEEEEEEEEEE~~SSS~~EEEEEEEE~~~THHHHTTTSSTTT~~~~~~~~TTSSS~~GGGG~~~SSSB~SS~EEEEEEEEEEE~~TT~EEEEEEE~~SS~~~~~TTS~~~EEEEGGGTGGGS~~SSS~HHHHHHHS~GGGEEEEEEEE~~~~~TTTTS~~EEEEEEEEEESS~~~EEEEEEEESSSSEEEEEEEEE~~EEETTEEEEEEEEEE~~HHHHHHHHHHHTSS~HHHHHHHHTT~EEEEEEEESSS~~EEEEEEEEEEE~~~~EEEEEEEE~~~GGGGTGGGTSSS~~~~~~~~~GGGSS~~GGGS~~~~SSSB~SS~EEEEEEEEEEEESSSEEEEEEEEE~~~~~~~~~~EEEGGGSGGGTT~~~HHHHHHHS~GGGEEEEEEEE~~~~~~EEEEEEEESS~~EEEEEEE~~~EEEE~~B~SSSEEEEE~S~~S~HHHHHHHHHHHTSS~HHHHHHHTTS~EEEEEEEETTT~~EEEEEEEEEEE~~EEEEEEEE~~~~S~~SSSSS~~GGGT~~

S M R S I A S S K L W M L E F S A F L E R Q Q D P D T Y N K H L F V H I P Y L E T V D I R Q I Y D K F P E K K G G L K E L F E R G P S N A F F L V K F W A D L N T N E G S A F Y G V S S Q Y E S P E N M I I T C S T K V C S F G K Q V V E K V E T E Y A R Y E N G H Y L Y R I H R S P L C E Y M I N F I H K L K H L P E K Y M M N S V L E N F T I L Q V V T N R D T Q E T L L C I A Y V F E V S A S A Q H H I Y R L V K E T D L E A L F N A V M N P K T A N V P Q T V P M R L R K L P D S F F K P P E S M R S I A S S K L W M L E F S A F L E R Q Q D P D T Y N K H L F V H I S Q D P Y L E T V D I R Q I Y D K F P E K K G G L K E L F E R G P S N A F F L V K F W A D L N T N I D D E G S A F Y G V S S Q Y E S P E N M I I T C S T K V C S F G K Q V V E K V E T E Y A R Y E N G H Y L Y R I H R S P L C E Y M I N F I H K L K H L P E K Y M M N S V L E N F T I L Q V V T N R D T Q E T L L C I A Y V F E V S A S E H G A Q H H I Y R L V K T D L E A L F N A V M N P K T A N V P Q T V P M R L R K L P D S F F K S M R S I A S S K L W M L E F S A F L E R Q Q D P D T Y N K H L F V H I S Q S S P S Y S D P Y L E T V D I R Q I Y D K F P E K K G G L K E L F E R G P S N A F F L V K F W A D L N T N I D D E G S A F Y G V S S Q Y E S P E N M I I T C S T K V C S F G K Q V V E K V E T E Y A R Y E N G H Y L Y R I H R S P L C E Y M I N F I H K L K H L P E K Y M M N S V L E N F T I L Q V V T N R D T Q E T L L C I A Y V F E V S A S A Q H H I Y R L V K T D L E A L F N A V M N P K T A N V P Q T V P M R L R K L P D S F F K P S M R S I A S S K L W M L E F S A F L E R Q Q D P D T Y N K H L F V H I S Q S D P Y L E T V D I R Q I Y D K F P E G G L K E L F E R G P S N A F F L V K F W A D L N T N Y G V S S Q Y E S P E N M I I T C S T K V C V E T E Y A R Y E N G H Y L Y R I H R S P L C E Y M I N F I H K L K H L P E K Y M M N S V L E N F T I L Q V V T N R D T Q E T L L C I A Y V F E V S A Q H H I Y R L V K V P Q T V P M R L R K L P D S F F K P

BS

UNSTRUCTURED

3KSQ

GFLSLDSPTYVLYRDRAEWADIDPVPQNDGPSPVVQIIYSEKFRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKDLQEEMNYITAIIEEQPKNYQVWHHRRVLVEWLKDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFRLWDNELQYVDQLLKEDVRNNSVWNQRHFVISNTTGYSDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSRYPNLLNQLLDLQPSHSSPYLIAFLVDIYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSKHSEPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPDGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYNVINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVMGVPENVLQPTHPVYNIGPDKVIQATTHFLQKPVPGF

~~~~TT~TT~~~GGG~GGGTTS~~~~~~~~SS~SSEE~~~HHHHHHHHHHHHHHHTT~~SHHHHHHHHHHHHH~TT~HHHHHHHHHHHHHTT~~HHHHHHHHHHHHHH~TT~HHHHHHHHHHHHHHT~~TTHHHHHHHHHHH~TT~HHHHHHHHHHHHHHT~~TTHHHHHHHHHHH~TT~HHHHHHHHHHHHTTT~S~SHHHHHHHHHHHHHHHHH~TT~HHHHHHHHHHHTTT~GGG~HHHHHHHHTSTTTS~~HHHHHHHHHHHHHHHHTT~SSHHHHHHHHHHHHHHHHHTT~GGGHHHHHHHHHHHHHHH~~~SGGGSGGGGGGS~~~TT~~~HHHHHHHHHHHHHHHHHHHHHHHT~~~~~~~~HHHHHHHHHHHHHEE~GGGGGGTT~HHHHHHHHHHHHHHTT~~~~HHHHHHHHHHHHHHB~TTSSEESSTT~~EEHHHHHHHHHHHHHH~~HHHHHHS~HHHHHHHHHHHB~TTS~BBSSTT~~B~HHHHHHHHHHHHHTT~~~TTTTTTHHHHHHTTB~TTSSB~SSTTS~~~HHHHHHHHHHHHHHT~GGGS~HHHHHHHHHTTB~TTT~SBBSSTTS~B~TTHHHHTTTHHHHHHHHHHHTT~TTS~SS~~SS~HHHHHHHHHHHSB~TTS~B~SSTTS~~BHHHHHHHHHHHHHHHEEEETTEEEE~~~SSGGG~~~~~~TTTSS~HHHHHHHHHHHTTS~~~~~

G F L S L D S P T Y V L Y R D R A E W A D I D P V P Q N D G P S P V V Q I I Y S E K F R D V Y D Y F R A V L Q R D E R S E R A F K L T R D A I E L N A A N Y T V W H F R R V L L R S L Q K D L Q E E M N Y I T A I I E E Q P K N Y Q V W H H R R V L V E W L K D P S Q E L E F I A D I L N Q D A K N Y H A W Q H R Q W V I Q E F R L W D N E L Q Y V D Q L L K E D V R N N S V W N Q R H F V I S N T T G Y S D R A V L E R E V Q Y T L E M I K L V P H N E S A W N Y L K G I L Q D R G L S R Y P N L L N Q L L D L Q P S H S S P Y L I A F L V D I Y E D M L E N Q C D N K E D I L N K A L E L C E I L A K E K D T I R K E Y W R Y I G R S L Q S K H S E P L Y S L R P E H A R E R L Q D D S V E T V T S I E Q A K V E E K I Q E V F S S Y K F N H L V P R L V L Q R E K H F H Y L K R G L R Q L T D A Y E C L D A S R P W L C Y W I L H S L E L L D E P I P Q I V A T D V C Q F L E L C Q S P D G G F G G G P G Q Y P H L A P T Y A A V N A L C I I G T E E A Y N V I N R E K L L Q Y L Y S L K Q P D G S F L M H V G G E V D V R S A Y C A A S V A S L T N I I T P D L F E G T A E W I A R C Q N W E G G I G G V P G M E A H G G Y T F C G L A A L V I L K K E R S L N L K S L L Q W V T S R Q M R F E G G F Q G R C N K L V D G C Y S F W Q A G L L P L L H R A L H A Q G D P A L S M S H W M F H Q Q A L Q E Y I L M C C Q C P A G G L L D K P G K S R D F Y H T C Y C L S G L S I A Q H F G S G A M L H D V V M G V P E N V L Q P T H P V Y N I G P D K V I Q A T T H F L Q K P V P G F

AH

UNSTRUCTURED

1JMX

EQGPSLLQNKCMGCHIPEGNDTYSRISHQRKTPEGWLMSIARMQVMHGLQISDDDRRTLVKYLADKQGLAPSETDGVRYAMERRLNTVEQFDTQLSETCGRCHSGARVALQRRPAKEWEHLVNFHLGQWPSLEYQAQARDRDWLPIALQQVVPDLAKRYPLESAAWAEWQKARPKADALPGQWAFSGHMLAKGDVRGVMSVTPDQGDTFKVEVKGAYADGTPFNGSGSAILYNGYEWRGNVKVGDANLRQVFAALDGEMKGRMFEAEHDERGLDFTAVKEGKARLLAVQPAFIKAGGESEITLVGSGLAGKPDLGAGVEVTEVLEQTPTLVRLKARAAADAKPGQREVAVGTLKGVNLAVYDKVEEVKVVPAFSIARIGENGASVPKVQGRFEAEAWGKDANGQPLRIGYLPASWKVEPFNERAVEDEDVKFAGKMQADGVFVPGGAGPNPERKMMTNNAGNLKVIATLADGGQTGEGHMIVTVQRWNNPPLPGPALKAGHEYMIVTNYPNNLHVVDVASDTVYKSCVMPDKFGPGTAMMAPDNRTAYVLNNHYGDIYGIDLDTCKNTFHANLSSVPGEVGRSMYSFAISPDGKEVYATVNPTQRLNDHYVVKPPRLEVFSTADGLEAKPVRTFPMPRQVYLMRAADDGSLYVAGPDIYKMDVKTGKYTVALPLRNWNRKGYSAPDVLYFWPHQSPRHEFSMLYTIARFATADLLYGYLSVDLKTGKTHTQEFADLTELYFTGLRSPKDPNQIYGVLNRLAKYDLKQRKLIKAANLDHTYYCVAFDKKGDKLYLGGTFNDLAVFNPDTLEKVKNIKLPGGDMSTTTPQVFIRAVAGCTATTDPGWEVDAFGGVSSLCQPMEADLYGCSDPCWPAQVPDMMSTYQDWNAQASNSAEDWRNLGTVFPKDK

~~HHHHHHHHHBTTB~EEETTEETTGGG~EE~HHHHHHHHHHHHHHH~~~~~HHHHHHHHHHHHHHT~~~GGGSTT~TTTTTT~TT~~~~~~HHHHHHHSSSS~SHHHHTEE~~HHHHHHHHHHHHHH~GGGGGSTTTTTTTHHHHHHHTHHHHHHHHS~S~~HHHHHHHHH~~~GGGS~EEEEEEEEETTTEEEEEEEEEEE~STTEEEEEEEEEETTS~EEEEEEEEEEETTTEEEEEEEETTEEEEEEEEEETTEEEEEEEETTEEEEEEEEEEEETTS~EEEEEESSEEETT~EEEEEEEEES~~S~EE~~TTEEEEEEEEE~SSEEEEEEEE~TT~~SEEEEEEETTEEEEEEEEES~~~EEEEESSEEEEE~B~TT~SS~~B~EE~EEEEEEE~TTS~EEEEEE~~EEEEEEESSHHHHHTTHHHHSEEE~TTSEEEE~BSS~~TTSGGG~~S~EEEEEEEEETTT~~EEEEEEEEE~~~S~~~S~~~~~~~TT~EEEEEEETTTEEEEEETTTTEEEEEEE~SS~~SS~EEEE~TTSSEEEEEETTTTEEEEEETTTTEEEEEEES~~STTEEEE~SS~EEE~TTSSEEEEEEEEEEE~SS~EEE~~~EEEEEEGGGGGGB~~SEEEE~~SS~~~EEE~TTS~EEEESSSEEEE~TTT~~EEEEE~STT~~~TTB~~~B~~~~~~~~~TT~EEEEEEEEEE~~~~EEEEEEEEEETTT~~EEEEEEEE~SS~EEEEEE~SS~TTEEEEEESEEEEEETTTTEEEEEEE~SS~~~EEEE~SSSS~EEEESBSSEEEEEETTTTEEEEEEE~SSS~~BT~~~EEEE~~~TTS~~~~SS~SSS~TTSSSSSS~SSGGGGHHHHHTTT~~~SS~~TTTT~TTTTTT~SSHHHHGGG~~~~S~~~~

E Q G P S L L Q N K C M G C H I P E G N D T Y S R I S H Q R K T P E G W L M S I A R M Q V M H G L Q I S D D D R R T L V K Y L A D K Q G L A P S E T D G V R Y A M E R R L N T V E Q F D T Q L S E T C G R C H S G A R V A L Q R R P A K E W E H L V N F H L G Q W P S L E Y Q A Q A R D R D W L P I A L Q Q V V P D L A K R Y P L E S A A W A E W Q K A R P K A D A L P G Q W A F S G H M L A K G D V R G V M S V T P D Q G D T F K V E V K G A Y A D G T P F N G S G S A I L Y N G Y E W R G N V K V G D A N L R Q V F A A L D G E M K G R M F E A E H D E R G L D F T A V K E G K A R L L A V Q P A F I K A G G E S E I T L V G S G L A G K P D L G A G V E V T E V L E Q T P T L V R L K A R A A A D A K P G Q R E V A V G T L K G V N L A V Y D K V E E V K V V P A F S I A R I G E N G A S V P K V Q G R F E A E A W G K D A N G Q P L R I G Y L P A S W K V E P F N E R A V E D E D V K F A G K M Q A D G V F V P G G A G P N P E R K M M T N N A G N L K V I A T L A D G G Q T G E G H M I V T V Q R W N N P P L P G P A L K A G H E Y M I V T N Y P N N L H V V D V A S D T V Y K S C V M P D K F G P G T A M M A P D N R T A Y V L N N H Y G D I Y G I D L D T C K N T F H A N L S S V P G E V G R S M Y S F A I S P D G K E V Y A T V N P T Q R L N D H Y V V K P P R L E V F S T A D G L E A K P V R T F P M P R Q V Y L M R A A D D G S L Y V A G P D I Y K M D V K T G K Y T V A L P L R N W N R K G Y S A P D V L Y F W P H Q S P R H E F S M L Y T I A R F A T A D L L Y G Y L S V D L K T G K T H T Q E F A D L T E L Y F T G L R S P K D P N Q I Y G V L N R L A K Y D L K Q R K L I K A A N L D H T Y Y C V A F D K K G D K L Y L G G T F N D L A V F N P D T L E K V K N I K L P G G D M S T T T P Q V F I R A V A G C T A T T D P G W E V D A F G G V S S L C Q P M E A D L Y G C S D P C W P A Q V P D M M S T Y Q D W N A Q A S N S A E D W R N L G T V F P K D K

BS

UNSTRUCTURED

2MU1

GHMQKTAFIWDLDGTLMPGAREVLAWADESGIQQFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTYYIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK

~~~~S~EEEE~SS~~~~TTHHHHHHHHHHTT~EEEEE~S~~THHHHHHHHHT~GGGSS~EE~GGG~~~SSS~THHHHHHHHTTT~~GGGEEEEESSSHHHHHHHHHT~EEEESS~~S~TTEEE~SSTTHHHHHTT~~

G H M Q K T A F I W D L D G T L M P G A R E V L A W A D E S G I Q Q F I Y T H K G N N A F T I L K D L G V E S Y F T E I L T S Q S G F V R K P S P E A A T Y L L D K Y Q L N S D N T Y Y I G D R T L D V E F A Q N S G I Q S I N F L E S T Y E G N H R I Q A L A D I S R I F E T K

AH

UNSTRUCTURED

2YFW

DLLISRMPFARLVKEVTDQFTTEEPLRWQSMAIMALQEASEAYLVGLLEHTNLLALHAKRITIMRKDMQLARRIRGQFITKPAIRRLARRGGVKRISGLIYEEVRNVLKTFLESVIRDAVTYTEHAKRKTVTSLDVVYALKRQGTDLLISRMPFARLVKEVTDQLRWQSMAIMALQEASEAYLVGLLEHTNLLALHAKRITIMRKDMQLARRIRGDNIQGITKPAIRRLARRGGVKRISGLIYEEVRNVLKTFLESVIRDAVTYTEHAKRKTVTSLDVVYALKRQGALAEIRKYQRSTDLLISRMPFARLVKEVTDQFTPLRWQSMAIMALQEASEAYLVGLLEHTNLLALHAKRITIMRKDMQLARRIRGQFIRDNIQGITKPAIRRLARRGGVKRISGLIYEEVRNVLKTFLESVIRDAVTYTEHAKRKTVTSLDVVYALKRQGTDLLISRMPFARLVKEVTDQFTTESEPLRWQSMAIMALQEASEAYLVGLLEHTNLLALHAKRITIMRKDMQLARRIRGRDNIQGITKPAIRRLARRGGVKRISGLIYEEVRNVLKTFLESVIRDAVTYTEHAKRKTVTSLDVVYALKRQGRTLYGFGG

~~~S~HHHHHHHHHHHHHHH~~~~~~EE~HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT~SEE~HHHHHHHHHHH~~~~~HHHHHHHHHHTT~~EE~TTHHHHHHHHHHHHHHHHHHHHHHHHHHTT~SEE~HHHHHHHHHHH~~~~SS~HHHHHHHHHHHHT~~EE~HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT~SEE~HHHHHHHHHHH~~~STTS~HHHHHHHHHHTT~~EE~THHHHHHHHHHHHHHHHHHHHHHHHHHHTT~SEE~HHHHHHHHHH~~~HHHHHHHHT~~S~~S~HHHHHHHHHHHHTT~~~~EE~HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT~SEE~HHHHHHHHHHH~~~~~~GGGGS~HHHHHHHHHHTT~SEE~TTHHHHHHHHHHHHHHHHHHHHHHHHHHTT~SEE~HHHHHHHHHH~~~~~SS~HHHHHHHHHHHHHHH~S~SS~~EE~HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT~SEE~HHHHHHHHHHH~~~GGGGS~HHHHHHHHHHTT~SEE~TTHHHHHHHHHHHHHHHHHHHHHHHHHHTT~SEE~HHHHHHHHT~SSS~SSSTT~

D L L I S R M P F A R L V K E V T D Q F T T E E P L R W Q S M A I M A L Q E A S E A Y L V G L L E H T N L L A L H A K R I T I M R K D M Q L A R R I R G Q F I T K P A I R R L A R R G G V K R I S G L I Y E E V R N V L K T F L E S V I R D A V T Y T E H A K R K T V T S L D V V Y A L K R Q G T D L L I S R M P F A R L V K E V T D Q L R W Q S M A I M A L Q E A S E A Y L V G L L E H T N L L A L H A K R I T I M R K D M Q L A R R I R G D N I Q G I T K P A I R R L A R R G G V K R I S G L I Y E E V R N V L K T F L E S V I R D A V T Y T E H A K R K T V T S L D V V Y A L K R Q G A L A E I R K Y Q R S T D L L I S R M P F A R L V K E V T D Q F T P L R W Q S M A I M A L Q E A S E A Y L V G L L E H T N L L A L H A K R I T I M R K D M Q L A R R I R G Q F I R D N I Q G I T K P A I R R L A R R G G V K R I S G L I Y E E V R N V L K T F L E S V I R D A V T Y T E H A K R K T V T S L D V V Y A L K R Q G T D L L I S R M P F A R L V K E V T D Q F T T E S E P L R W Q S M A I M A L Q E A S E A Y L V G L L E H T N L L A L H A K R I T I M R K D M Q L A R R I R G R D N I Q G I T K P A I R R L A R R G G V K R I S G L I Y E E V R N V L K T F L E S V I R D A V T Y T E H A K R K T V T S L D V V Y A L K R Q G R T L Y G F G G

AH

UNSTRUCTURED

2DRE

NDEEPVKDTNGNPLKIETRYFIQPASDNNGGGLVPANVDLSHLCPLGIVRTSLPYQPGLPVTISTPSSSEGNDVLTNTNIAITFDAPIWLCPSSKTWTVDSSSEEKYIITGGDPKSGESFFRIEKYGNGKNTYKLVRYDNGEGKSVGSTKSLWGPALVLNDNAFPIKFREVDEEPVKDTNGNPLKIETRYFIQPASDNNGGGLVPANVDLSHLCPLGIVRTSLPYQPGLPVTISTPSSSEGNDVLTNTNIAITFDAPIWLCPSSKTWTVDSSSEEKYIITGGDPKSGESFFRIEKYGNGKNTYKLVRGEGKSVGSTKSLWGPALVLNDDDDSDENAFPIKFREVDDEEPVKDTNGNPLKIETRYFIQPASDNNGGGLVPANVDLSHLCPLGIVRTSLPYQPGLPVTISTPSSSEGNDVLTNTNIAITFDAPIWLCPSSKTWTVDSSSEEKYIITGGDPKSGESFFRIEKYGNGKNTYKLVRYDNGEGKSVGSTKSLWGPALVLNDDDDSDENAFPIKFREVDDEEPVKDTNGNPLKIETRYFIQPASDNNGGGLVPANVDLSHLCPLGIVRTSLPYQPGLPVTISTPSSSEGNDVLTNTNIAITFDAPIWLCPSSKTWTVDSSSEEKYIITGGDPKSGESFFRIEKYGNGKNTYKLVRYDNGEGKSVGSTKSLWGPALVLNDDDDSDENAFPIKFREVD

~~~~B~B~TTS~B~BTT~~EEEEESS~SSS~~EEEE~SSSS~SSS~EEEE~SSTT~~~~~EEEE~TT~~SSSB~BTTS~BEEEE~~S~~SSSS~SB~EE~SSSTT~BEES~~~TTSGGG~BEEEE~SSSTT~EEEEEESSSSEEEEEEEE~SSSEEEEE~~~~~~EEEEE~~~~B~B~TTS~B~BTT~~EEEEE~SS~SS~~EEEE~SSSS~SSS~EEEE~~STT~~~~EEEEE~S~SSSTTB~BTTS~BEEEE~~S~~SSSS~SB~EE~SSSSS~BEES~~~TTSGGG~BEEEE~TTSSS~EEEE~~~~~BEEEEE~SSSEEEEE~SS~~STTS~~~EEEEE~~~~~B~B~TTS~B~BTT~~EEEEESS~SSS~~EEEE~SBTTBSSS~EEEE~~STT~~~~~EEEE~SSS~STTB~BTTSEEEEEE~~S~~SSSS~SB~EE~TTSSS~BEES~~~TTSTTSEEEEEE~SSSTT~EEEEEESSS~EEEEEEEEETTEEEEEE~S~~SSSTT~~~EEEEE~~~~~B~B~TTS~B~BTT~EEEEEESS~~SS~~EEEE~SBTTBSSS~EEEE~SSTT~~~~~EEEE~HHSSSTTB~BSSS~BEEEE~~S~~SSSS~SEEEE~SS~TT~BEEEEE~SSSGGG~BEEEE~SSSTT~EEEEEESSS~EEEEEEEEETTEEEEEE~S~~S~GGG~~~EEEEE~~

N D E E P V K D T N G N P L K I E T R Y F I Q P A S D N N G G G L V P A N V D L S H L C P L G I V R T S L P Y Q P G L P V T I S T P S S S E G N D V L T N T N I A I T F D A P I W L C P S S K T W T V D S S S E E K Y I I T G G D P K S G E S F F R I E K Y G N G K N T Y K L V R Y D N G E G K S V G S T K S L W G P A L V L N D N A F P I K F R E V D E E P V K D T N G N P L K I E T R Y F I Q P A S D N N G G G L V P A N V D L S H L C P L G I V R T S L P Y Q P G L P V T I S T P S S S E G N D V L T N T N I A I T F D A P I W L C P S S K T W T V D S S S E E K Y I I T G G D P K S G E S F F R I E K Y G N G K N T Y K L V R G E G K S V G S T K S L W G P A L V L N D D D D S D E N A F P I K F R E V D D E E P V K D T N G N P L K I E T R Y F I Q P A S D N N G G G L V P A N V D L S H L C P L G I V R T S L P Y Q P G L P V T I S T P S S S E G N D V L T N T N I A I T F D A P I W L C P S S K T W T V D S S S E E K Y I I T G G D P K S G E S F F R I E K Y G N G K N T Y K L V R Y D N G E G K S V G S T K S L W G P A L V L N D D D D S D E N A F P I K F R E V D D E E P V K D T N G N P L K I E T R Y F I Q P A S D N N G G G L V P A N V D L S H L C P L G I V R T S L P Y Q P G L P V T I S T P S S S E G N D V L T N T N I A I T F D A P I W L C P S S K T W T V D S S S E E K Y I I T G G D P K S G E S F F R I E K Y G N G K N T Y K L V R Y D N G E G K S V G S T K S L W G P A L V L N D D D D S D E N A F P I K F R E V D

BS

UNSTRUCTURED

4H43

STNKHLKNNFNSLHNQMRKMPVSHFKEALDVPDYSGMRQSGFFAMSQGFQLNNHGYDVFIHARRESPQSQGKFAGDKFNISVLRDMVPQAFQALSGLLFSEDSPVDKWKVTDMEKVVQQARVSLGAQFTLYIKPDQENSQYSASFLHKTRQFIECLESRLSENGVISGQCPESDVHPENWKYLSYRNELRSGRDGGEMQRQALREEPFYRLMTESTNKHLKNNFNSLHNQMRKMPVSHFKEALDVPDYSGMRQSGFFAMSQGFQLNNHGYDVFIHARRESPQSQGKFAGDKFNISVLRDMVPQAFQALSGLLFSEDSPVDKWKVTDMEKVVQQARVSLGAQFTLYIKPDQENSQYSASFLHKTRQFIECLESRLSENGVISGQCPESDVHPENWKYLSYRNELRSGRDGGEMQRQALREEPFYRLMTE

~HHHHHHHTHHHHHHHHTTS~~~~~~~~SS~~~HHHHHTTTT~EEETTEEEE~~TTSSEEEEEESS~S~~S~~~SEEEEE~B~GGGHHHHHHHHHHHHT~TT~S~SEEEEE~TTTB~TTSHHHHS~~EEEE~~~SSTTS~~~HHHHHHHHHHHHHHHHHHHHTT~~B~~~~TT~B~~TT~SSEEEEESSS~~SS~TTHHHHHHHT~HHHHHHH~~HHHHHHHTHHHHHHHHTTS~~~~~~~~SS~~~HHHHHT~TT~EEETTEEEE~~TT~SEEEEEESS~S~~S~~~SEEEEE~B~GGGHHHHHHHHHHHHT~TT~S~SEEEEE~GGGB~TTSHHHHS~~EEEE~~~SSTTS~~~HHHHHHHHHHHHHHHHHHHHTT~~B~~~~TT~B~~TT~SSEEEEEGGG~~SS~HHHHHHHHHT~HHHHHHH~

S T N K H L K N N F N S L H N Q M R K M P V S H F K E A L D V P D Y S G M R Q S G F F A M S Q G F Q L N N H G Y D V F I H A R R E S P Q S Q G K F A G D K F N I S V L R D M V P Q A F Q A L S G L L F S E D S P V D K W K V T D M E K V V Q Q A R V S L G A Q F T L Y I K P D Q E N S Q Y S A S F L H K T R Q F I E C L E S R L S E N G V I S G Q C P E S D V H P E N W K Y L S Y R N E L R S G R D G G E M Q R Q A L R E E P F Y R L M T E S T N K H L K N N F N S L H N Q M R K M P V S H F K E A L D V P D Y S G M R Q S G F F A M S Q G F Q L N N H G Y D V F I H A R R E S P Q S Q G K F A G D K F N I S V L R D M V P Q A F Q A L S G L L F S E D S P V D K W K V T D M E K V V Q Q A R V S L G A Q F T L Y I K P D Q E N S Q Y S A S F L H K T R Q F I E C L E S R L S E N G V I S G Q C P E S D V H P E N W K Y L S Y R N E L R S G R D G G E M Q R Q A L R E E P F Y R L M T E

AH

UNSTRUCTURED

2WQ0

MKQLEDKIEENTSKIYHNTNEIARNTKLVGE

~HHHHHHHHHHHHHHHHHHHHHHHHHHHH~~

M K Q L E D K I E E N T S K I Y H N T N E I A R N T K L V G E

AH

UNSTRUCTURED

2H2J

LSPAVQTFWKWLQEEGVITAKTPVKASVVTEGLGLVALKDISRNDVILQVPKRLWINPDAVAASEIGRVCSELKPWLSVILFLIRERSREDSVWKHYFGILPQETDSTIYWSEEELQELQGSQLLKTTVSVKEYVKNECLKLEQEIILPNKRLFPDPVTLDDFFWAFGILRSRAFSRLNLVVVPMADLINHSAGVTTEDHAYEYLFSLKSPLSVKAGEQVYIQYDLNKSNAELALDYGFIEPNENRHAYTLTLEISESDPFFDDKLDVAESNGFAQTAYFDIFYNRTLPPGLLPYLRLVALGGTDAFLLESLFRDTIWGHLELSVSRDNEELLCKAVREACKSALAGYHTTIEQDRELKEGNLDSRLAIAVGIREGEKMVLQQIDGIFEQKELELDQLEYYQERRLKDLGLCGENGDILENLYSLSPAVQTFWKWLQEEGVITAKTPVKASVVTEGLGLVALKDISRNDVILQVPKRLWINPDAVAASEIGRVCSELKPWLSVILFLIRERSREDSVWKHYFGILPQETDSTIYWSEEELQELQGSQLLKTTVSVKEYVKNECLKLEQEIILPNKRLFPDPVTLDDFFWAFGILRSRAFSRLRNENLVVVPMADLINHSAGVTTEDHAYEVKGAAGLFSWDYLFSLKSPLSVKAGEQVYIQYDLNKSNAELALDYGFIEPNENRHAYTLTLEISESDPFFDDKLDVAESNGFAQTAYFDIFYNRTLPPGLLPYLRLVALGGTDAFLLESLFRDTIWGHLELSVSRDNEELLCKAVREACKSALAGYHTTIEQDRELKEGNLDSRLAIAVGIREGEKMVLQQIDGIFEQKELELDQLEYYQERRLKDLGLCGENGDILENLYFLSPAVQTFWKWLQEEGVITAKTPVKASVVTEGLGLVALKDISRNDVILQVPKRLWINPDAVAASEIGRVCSELKPWLSVILFLIRERSREDSVWKHYFGILPQETDSTIYWSEEELQELQGSQLLKTTVSVKEYVKNECLKLEQEIILPNKRLFPDPVTLDDFFWAFGILRSRAFSRLRNENLVVVPMADLINHSAGVTTEDHAYEVKGAAGLFSWDYLFSLKSPLSVKAGEQVYIQYDLNKSNAELALDYGFIEPNENRHAYTLTLEISESDPFFDDKLDVAESNGFAQTAYFDIFYNRTLPPGLLPYLRLVALGGTDAFLLESLFRDTIWGHLELSVSRDNEELLCKAVREACKSALAGYHTTIEQDRELKEGNLDSRLAIAVGIREGEKMVLQQIDGIFEQKELELDQLEYYQERRLKDLGLCGENGDILENLYF

~~HHHHHHHHHHHTTTSS~SS~~~EEEEETTEEEEE~SS~~~TT~EEEEEEGGG~~SHHHHHTSGGGTTTTTS~HHHHHHHHHHHHHH~TT~TTHHHHTTS~S~~S~GGG~~HHHHHTTTT~HHHHHHHHHHHHHHHHHHHHHHHTTTTTTTT~~S~~~HHHHHHHHHHHHHHSB~~~~~B~~TTGGG~EE~SS~~S~~~~~~~EEEEE~SS~~~TTSB~EE~S~SS~~HHHHHHHSS~~~S~GGG~EEEEEEE~~TTSTTHHHHHHHHHTTT~~SEEEEEEETTS~~~TTHHHHHHHHH~~GGGGGGGSGGGTTTHHHHHHH~~~HHHHHHHHHHHHHHHHHHHTT~SS~HHHHHHHTTS~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHGGGTS~~HHHHHHTT~~SS~~~THHHHT~~~HHHHHHHHHHHHHHTTS~~TT~~EEEEEETTEEEEEESS~B~TT~EEEEEEGGG~BSHHHHHTSTTTTTTTTS~HHHHHHHHHHHHHH~TT~TTHHHHTTS~S~~S~GGG~~HHHHHTTTT~HHHHHHHHHHHHHHHHHHHHHHHTTTTTTTT~~S~~~HHHHHHHHHHHHHH~B~SSSS~S~BB~TTGGG~EE~TT~~~~~~EEEE~GGGT~~GGG~EEEEE~SS~B~TTSB~EE~S~TT~~HHHHHHHSS~~~S~GGG~EEEEEEE~~TTSTTHHHHHHHHHTTT~~SEEEEEEETTS~~~TTHHHHHHHHH~~SGGGGGGSTTTTTTHHHHHHH~~~HHHHHHHHHHHHHHHHHHHTT~SS~HHHHHHHHHS~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSTTTS~~HHHHHTTT~~~S~~~HHHHTTT~~~~HHHHHHHHHHHHTT~S~TT~~EEEEEETTEEEEEESS~B~TT~EEEEEEGGG~~SHHHHHTSGGGTTTTTS~HHHHHHHHHHHHHH~TT~TTHHHHTTS~S~~S~GGG~~HHHHHTTTT~HHHHHHHHHHHHHHHHHHHHHTTTTTTTTTT~~S~~~HHHHHHHHHHHHHH~B~~SSS~S~B~~TTGGG~EE~TT~~~~S~SEEEE~~TT~~GGG~EEEEE~SS~B~TTSB~EE~S~TT~~HHHHHHHSS~~~S~GGG~EEEEEEE~~TTSTTHHHHHHHHHTTT~~SEEEEEEETTS~~~TTHHHHHHHHH~~TTTGGGGSTTTTTTHHHHHHH~~~HHHHHHHHHHHHHHHHHHHTT~SS~HHHHHHHHTS~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTS~~HHHHHTS~~~~S~~~THHHHTT~~

L S P A V Q T F W K W L Q E E G V I T A K T P V K A S V V T E G L G L V A L K D I S R N D V I L Q V P K R L W I N P D A V A A S E I G R V C S E L K P W L S V I L F L I R E R S R E D S V W K H Y F G I L P Q E T D S T I Y W S E E E L Q E L Q G S Q L L K T T V S V K E Y V K N E C L K L E Q E I I L P N K R L F P D P V T L D D F F W A F G I L R S R A F S R L N L V V V P M A D L I N H S A G V T T E D H A Y E Y L F S L K S P L S V K A G E Q V Y I Q Y D L N K S N A E L A L D Y G F I E P N E N R H A Y T L T L E I S E S D P F F D D K L D V A E S N G F A Q T A Y F D I F Y N R T L P P G L L P Y L R L V A L G G T D A F L L E S L F R D T I W G H L E L S V S R D N E E L L C K A V R E A C K S A L A G Y H T T I E Q D R E L K E G N L D S R L A I A V G I R E G E K M V L Q Q I D G I F E Q K E L E L D Q L E Y Y Q E R R L K D L G L C G E N G D I L E N L Y S L S P A V Q T F W K W L Q E E G V I T A K T P V K A S V V T E G L G L V A L K D I S R N D V I L Q V P K R L W I N P D A V A A S E I G R V C S E L K P W L S V I L F L I R E R S R E D S V W K H Y F G I L P Q E T D S T I Y W S E E E L Q E L Q G S Q L L K T T V S V K E Y V K N E C L K L E Q E I I L P N K R L F P D P V T L D D F F W A F G I L R S R A F S R L R N E N L V V V P M A D L I N H S A G V T T E D H A Y E V K G A A G L F S W D Y L F S L K S P L S V K A G E Q V Y I Q Y D L N K S N A E L A L D Y G F I E P N E N R H A Y T L T L E I S E S D P F F D D K L D V A E S N G F A Q T A Y F D I F Y N R T L P P G L L P Y L R L V A L G G T D A F L L E S L F R D T I W G H L E L S V S R D N E E L L C K A V R E A C K S A L A G Y H T T I E Q D R E L K E G N L D S R L A I A V G I R E G E K M V L Q Q I D G I F E Q K E L E L D Q L E Y Y Q E R R L K D L G L C G E N G D I L E N L Y F L S P A V Q T F W K W L Q E E G V I T A K T P V K A S V V T E G L G L V A L K D I S R N D V I L Q V P K R L W I N P D A V A A S E I G R V C S E L K P W L S V I L F L I R E R S R E D S V W K H Y F G I L P Q E T D S T I Y W S E E E L Q E L Q G S Q L L K T T V S V K E Y V K N E C L K L E Q E I I L P N K R L F P D P V T L D D F F W A F G I L R S R A F S R L R N E N L V V V P M A D L I N H S A G V T T E D H A Y E V K G A A G L F S W D Y L F S L K S P L S V K A G E Q V Y I Q Y D L N K S N A E L A L D Y G F I E P N E N R H A Y T L T L E I S E S D P F F D D K L D V A E S N G F A Q T A Y F D I F Y N R T L P P G L L P Y L R L V A L G G T D A F L L E S L F R D T I W G H L E L S V S R D N E E L L C K A V R E A C K S A L A G Y H T T I E Q D R E L K E G N L D S R L A I A V G I R E G E K M V L Q Q I D G I F E Q K E L E L D Q L E Y Y Q E R R L K D L G L C G E N G D I L E N L Y F

AH

UNSTRUCTURED

1CUC

RTTRDDLINGNSASCADVIFIYARGSTETGNLGTLGPSIASNLESAFGKDGVWIQGVGGAYRATLGDNALPRGTSSAAIREMLGLFQQANTKCPDATLIAGGYSQGAALAAASIEDLDSAIRDKIAGTVLFGYTKNLQNRGRIPNYPADRTKVFCKTGDLVCTGSLIVAAPHLAYGPDAEGPAPEFLIEKVRAVRGS

~~~~BHHHH~~GGG~~SEEEEEE~~TT~STTTTTTHHHHHHHHHHHH~TTTEEEEE~~TT~~~~GGGGGSTTSS~HHHHHHHHHHHHHHHHH~TT~EEEEEEETHHHHHHHHHHHHS~HHHHTTEEEEEEES~TTTTTTTT~~TTS~GGGEEEE~~TT~GGGGT~~~~~GGGG~~HHHHHTHHHHHHHHHHHHHH~~

R T T R D D L I N G N S A S C A D V I F I Y A R G S T E T G N L G T L G P S I A S N L E S A F G K D G V W I Q G V G G A Y R A T L G D N A L P R G T S S A A I R E M L G L F Q Q A N T K C P D A T L I A G G Y S Q G A A L A A A S I E D L D S A I R D K I A G T V L F G Y T K N L Q N R G R I P N Y P A D R T K V F C K T G D L V C T G S L I V A A P H L A Y G P D A E G P A P E F L I E K V R A V R G S

AH

UNSTRUCTURED

1PVX

GTTPNSEGWHDGYYYSWWSDGGGDSTYTNNSGGTYEITWGNGGNLVGGKGWNPGLNARAIHFTGVYQPNGTSYLSVYGWTRNPLVEYYIVENFGSSNPSSGSTDLGTVSCDGSTYTLGQSTRYNAPSIDGTQTFNQYWSVRQDKRSSGTVQTGCHFDAWASAGLNVTGDHYYQIVATEGYFSSGYARITVADVG

~~~~~EEEEETTEEEEEEE~S~S~EEEEE~STTEEEEEE~SSSEEEEEEEESS~~SS~EEEEEEEEEESSSEEEEEEEEEETTTEEEEEEEEESSS~TTTTSEEEEEEEETTEEEEEEEEEEEEEEETTEEEEEEEEEEEESS~~SSEEEEHHHHHHHHHHTT~~~~SEEEEEEEEEEEESS~EEEEEEEEE~~

G T T P N S E G W H D G Y Y Y S W W S D G G G D S T Y T N N S G G T Y E I T W G N G G N L V G G K G W N P G L N A R A I H F T G V Y Q P N G T S Y L S V Y G W T R N P L V E Y Y I V E N F G S S N P S S G S T D L G T V S C D G S T Y T L G Q S T R Y N A P S I D G T Q T F N Q Y W S V R Q D K R S S G T V Q T G C H F D A W A S A G L N V T G D H Y Y Q I V A T E G Y F S S G Y A R I T V A D V G

BS

BEND

5AO1

MKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLDSLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAISQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLEDSLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDNPIDHVSFYCKTAPNRAIEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRISQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDPGMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDKNPIDHVSFYCKTAPNRAIEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQ

~EEEEETTTEEEEE~HHHHHHHSSHHHHGGGGSBTTGGGGGT~TT~~~BHHHHHHHHHHHHHHHHHHHHHH~GGG~~~HHHHHHHHHHHHHTTTT~~TTTHHHHHTHHHHH~TT~~~~HHHHHHHHHHHHHHHTTHHHHHHHTT~~HHHHHHHHHHHHH~~~~~S~~~SSS~GGGGGGGGSS~~TTT~~SHHHHHHHHHHHHHHT~~~~~~HHHHHHH~EEEEETTEEEEEEEGGGHHHHHHHHHHHHHHHHHTTT~HHHHHHHHHHHHHHHHHHTT~~EE~GGG~EE~TTTGGG~HHHHHT~STHHHHHHHH~~~GGGHHHHHHHHHHHTT~~~EEEEEE~~TTS~~~~GGGGGGHHHHHHTS~~SS~~S~~~~GGGEEEEEEESSTT~~~~~TTTT~~EEETTEEEEE~~~SS~S~SS~EEEEEEES~~SHHHHHHHHHHHHHHHHHTT~~~~~~~EEEEETTTEEEEE~HHHHHHHSSHHHHGGGGSBTTGGGGGT~TT~~~BHHHHHHHHHHHHHHHHHHHHHH~GGG~~~HHHHHHHHHHHHHTTTT~~TTTHHHHHTHHHHH~TT~~~~HHHHHHHHHHHHHHHHTHHHHHHHTT~~HHHHHHHHHHHHH~~~~~~S~~~SSS~GGGGGGGGTS~~~TTS~~HHHHHHHHHHHHHHT~~~~~~HHHHHHH~EEEEETTEEEEEEEGGGHHHHHHHHHHHHHHHHHTTT~HHHHHHHHHHHHHHHHHHTT~~EE~GGG~EE~TTTGGG~HHHHHT~STHHHHHHHH~~~GGGHHHHHHHHHHHTT~~~EEEEEE~~~TT~~~~GGGTTHHHHHHHT~~~SS~~S~~~~GGGEEEEEEE~~~GGGGS~EE~SSSTTBB~~EEEEEEES~~SHHHHHHHHHHHHHHHHHTT~~~~~~~EEEEETTTEEEEE~HHHHHHHSSHHHHGGGGSBTTGGGGGT~TT~~~BHHHHHHHHHHHHHHHHHHHHHH~GGG~~~HHHHHHHHHHHHHTTTT~~TTTHHHHHTHHHHH~TT~~~~HHHHHHHHHHHHHHHTTHHHHHHHTT~~HHHHHHHHHHHHH~~~~~~~SSS~GGGGGGGGTS~~TTT~~SHHHHHHHHHHHHHHT~~~~~~HHHHHHH~EEEEETTEEEEEEEGGGHHHHHHHHHHHHHHHHHTTT~HHHHHHHHHHHHHHHHHHTT~~EE~GGG~EE~TTTGGG~HHHHHT~STHHHHHHHH~~~GGGHHHHHHHHHHHHT~~~EEEEEE~~~SS~~~~GGGTTTHHHHHHT~~~SS~~SS~~~GGGEEEEEEESSTT~~~~~TTTT~~EE~SSSTTBB~~~~~SS~S~SS~EEEEEEES~~SHHHHHHHHHHHHHHHHTTT~~~~~~~~~EEEEETTTEEEEE~HHHHHHHSSHHHHGGGGSBSSGGGGGT~TT~~~BHHHHHHHHHHHHHHHHHHHHHH~GGG~~~HHHHHHHHHHHHHTTTT~~TTTHHHHHTHHHHH~TT~~~~HHHHHHHHHHHHHHHTTHHHHHHHTT~~HHHHHHHHHHHHH~~~~~~~SSS~GGGGGGGGSS~~~SS~~~HHHHHHHHHHHHHHT~~~~~~HHHHHHH~EEEEETTEEEEEEEGGGHHHHHHHHHHHHHHHHHTTT~HHHHHHHHHHHHHHHHHTTT~~EE~GGG~EE~TTTGGG~HHHHTT~STHHHHHHHH~~~GGGHHHHHHHHHHHTT~~~EEEEEE~B~SS~~~~GGGTTTHHHHHHT~~~SS~~S~~~~GGGEEEEEEE~~~~GGGGS~EEBTTB~S~~~~EEEEEEES~~SHHHHHHHHHHHHHHHHHTTB~~~~

M K V I N D P I H G H I E L H P L L V R I I D T P Q F Q R L R Y I K Q L G G G Y Y V F P G A S H N R F E H S L G V G Y L A G C L V H A L G E K Q P E L Q I S E R D V L C V Q I A G L C H D L G H G P F S H M F D G R F I P L A R P E V K W T H E Q G S V M M F E H L I N S N G I K P V M E Q Y G L I P E E D I C F I K E Q I V G P L D S L W P Y K G R P E N K S F L Y E I V S N K R N G I D V D K W D Y F A R D C H H L G I Q N N F D Y K R F I K F A R V C E V D N E L R I C A R D K E V G N L Y D M F H T R N S L H R R A Y Q H K V G N I I D T M I T D A F L K A D D Y I E I T G A G G K K Y R I S T A I D D M E A Y T K L T D N I F L E I L Y S T D P K L K D A R E I L K Q I E Y R N L F K Y V G E T Q P T G Q I K I K R E D Y E S L P K E V A S A K P K V L L D V K L K A E D F I V D V I N M D Y G M Q E K N P I D H V S F Y C K T A P N R A I S Q L L P E K F A E Q L I R V Y C K K V D R K S L Y A A R Q Y F V Q W C A D R N F T K P Q D M K V I N D P I H G H I E L H P L L V R I I D T P Q F Q R L R Y I K Q L G G G Y Y V F P G A S H N R F E H S L G V G Y L A G C L V H A L G E K Q P E L Q I S E R D V L C V Q I A G L C H D L G H G P F S H M F D G R F I P L A R P E V K W T H E Q G S V M M F E H L I N S N G I K P V M E Q Y G L I P E E D I C F I K E Q I V G P L E D S L W P Y K G R P E N K S F L Y E I V S N K R N G I D V D K W D Y F A R D C H H L G I Q N N F D Y K R F I K F A R V C E V D N E L R I C A R D K E V G N L Y D M F H T R N S L H R R A Y Q H K V G N I I D T M I T D A F L K A D D Y I E I T G A G G K K Y R I S T A I D D M E A Y T K L T D N I F L E I L Y S T D P K L K D A R E I L K Q I E Y R N L F K Y V G E T Q P T G Q I K I K R E D Y E S L P K E V A S A K P K V L L D V K L K A E D F I V D V I N M D N P I D H V S F Y C K T A P N R A I E Q L I R V Y C K K V D R K S L Y A A R Q Y F V Q W C A D R N F T K P Q D M K V I N D P I H G H I E L H P L L V R I I D T P Q F Q R L R Y I K Q L G G G Y Y V F P G A S H N R F E H S L G V G Y L A G C L V H A L G E K Q P E L Q I S E R D V L C V Q I A G L C H D L G H G P F S H M F D G R F I P L A R P E V K W T H E Q G S V M M F E H L I N S N G I K P V M E Q Y G L I P E E D I C F I K E Q I V G P L L W P Y K G R P E N K S F L Y E I V S N K R N G I D V D K W D Y F A R D C H H L G I Q N N F D Y K R F I K F A R V C E V D N E L R I C A R D K E V G N L Y D M F H T R N S L H R R A Y Q H K V G N I I D T M I T D A F L K A D D Y I E I T G A G G K K Y R I S T A I D D M E A Y T K L T D N I F L E I L Y S T D P K L K D A R E I L K Q I E Y R N L F K Y V G E T Q P T G Q I K I K R E D Y E S L P K E V A S A K P K V L L D V K L K A E D F I V D V I N M D Y G M Q E K N P I D H V S F Y C K T A P N R A I R I S Q L L P E K F A E Q L I R V Y C K K V D R K S L Y A A R Q Y F V Q W C A D R N F T K P Q D P G M K V I N D P I H G H I E L H P L L V R I I D T P Q F Q R L R Y I K Q L G G G Y Y V F P G A S H N R F E H S L G V G Y L A G C L V H A L G E K Q P E L Q I S E R D V L C V Q I A G L C H D L G H G P F S H M F D G R F I P L A R P E V K W T H E Q G S V M M F E H L I N S N G I K P V M E Q Y G L I P E E D I C F I K E Q I V G P L L W P Y K G R P E N K S F L Y E I V S N K R N G I D V D K W D Y F A R D C H H L G I Q N N F D Y K R F I K F A R V C E V D N E L R I C A R D K E V G N L Y D M F H T R N S L H R R A Y Q H K V G N I I D T M I T D A F L K A D D Y I E I T G A G G K K Y R I S T A I D D M E A Y T K L T D N I F L E I L Y S T D P K L K D A R E I L K Q I E Y R N L F K Y V G E T Q P T G Q I K I K R E D Y E S L P K E V A S A K P K V L L D V K L K A E D F I V D V I N M D K N P I D H V S F Y C K T A P N R A I E Q L I R V Y C K K V D R K S L Y A A R Q Y F V Q W C A D R N F T K P Q

AH

UNSTRUCTURED

2B48

MSQSNRELVVDFLSYKLSQKGYSWPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNNAA

~HHHHHHHHHHHHHHHHHHTT~~~~~HHHHHHHHHHHHHHHHH~~STTTTTTTTTS~~TE~~HHHHHHHHHHHHSS~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTS~HHHHHHHHSS~~~

M S Q S N R E L V V D F L S Y K L S Q K G Y S W P M A A V K Q A L R E A G D E F E L R Y R R A F S D L T S Q L H I T P G T A Y Q S F E Q V V N E L F R D G V N W G R I V A F F S F G G A L C V E S V D K E M Q V L V S R I A A W M A T Y L N D H L E P W I Q E N G G W D T F V E L Y G N N A A

AH

UNSTRUCTURED

4ERM

NLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAINNLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAINNLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAINNLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAINNLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQLSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISIPELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDELIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDLFVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIPWINTWLSEVDTDDLSNFQLAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQLSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISIPELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDELIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDLFVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIPWINTWLVQIDSEVDTDDLSNFQLAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQLSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISIPELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDELIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDLFVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIPWINTWLVQIDSEVDTDDLSNFQLAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQLSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISIPELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDELIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDLFVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIPWINTWLVSIDSEVDTDDLSNFQL

~~EEE~TTS~EEE~~HHHHHHHHHHHTTT~SS~~HHHHHHHHT~~~~SSEEHHHHHHHHHHHHHHH~~SS~TTHHHHHHHHHHHHHHHHHHSSSS~~~HHHHHHHHHHHTSS~THHHHHS~HHHHHHHTTT~~GGGGGSS~HHHHHHHHHTTS~B~TTT~~B~~~HHHHHHHHHHHHTTTS~TTTHHHHHHHHHHHHTTTSEE~~HHHHHHTTSS~~~~~~EEEEE~~SSHHHHHHHHHHHHHHHTTT~EEEEE~TTS~~TT~EEGGGTEE~~~SHHHHHHHHHHHHSSSBTTTBS~~BEEEEETTBTTHHHHTTTT~SSS~GGG~~~SSEEEEEE~HHHHHHHHTT~EEE~B~TTTSTTHHHHHHH~HHHHHHHHHHHHH~TTS~~~EEEHHHHHHHHHHHHHHTS~EEEEEHHHHHHS~SB~TTTS~~~~~~TTS~~~~~~B~~SSTT~SS~B~EE~~EEEEETTT~SSGGGHHHHHHHHHHHHHHHHHHS~~SSHHHHHHHHHH~~~EEEEE~HHHHHHHTT~~SSS~TTHHHHHHHHHHHHHHHHHHHHHHHHHH~~~TTGGGBGGGGT~~TTTSS~GGGGGS~~~~~~S~HHHHHHHHHHH~~SSS~~B~~~~~HHHHTTTT~~SSS~~~SSTEEEEE~SSSEEEEE~TTHHHHTTT~~~GGG~S~STTHHHHHHHHHTT~SS~~~~~EEE~TTSSGGG~B~HHHHHHHHHHHHHTT~~EE~~EEE~~~~EEE~TTS~EEE~~HHHHHHHHHHHTTT~SS~~HHHHHHHHT~~~~TT~BHHHHHHHHHHHHHHT~~SS~TTHHHHHHHHHHHHHHHHHHSSSS~~~HHHHHHHHHHHTSS~THHHHHS~HHHHHHHTTT~~GGGGGSS~HHHHHHHHHTTS~B~TTT~~B~~~HHHHHHHHHHHHSTTS~TTTHHHHHHHHHHHHTTTSEE~~HHHHHHTTSS~~~~~~EEEE~~~SSHHHHHHHHHHHHHHHTTT~EEEE~GGGS~~TT~EEGGGTEE~~~SHHHHHHHHHHHSTTSGGGTSS~~EEEEEETT~TTHHHHTTTT~SSS~GGG~~~SSEEEEEE~HHHHHHHHTT~EEE~~~TTTSTTHHHHHHH~HHHHHHHHHHHHH~TTS~~~EEEHHHHHHHHHHHHHHTS~EEEEEHHHHHHS~SS~TTTS~~~~~~TTS~~~~~~B~~SSTT~SS~B~EE~~~~EEETTT~SSGGGHHHHHHHHHHHHHHHHHHS~~SSHHHHHHHHHH~~~~~EEE~HHHHHHHTT~~SSS~TTHHHHHHHHHHHHHHHHHHHHHHHHHH~~~TTGGGSGGGGT~~HHHHS~GGGGGS~~~~~~S~HHHHHHHHTTT~~SSS~~~~~~~~HHHHHHHT~~STT~~~SSTEEEEE~SSSEEEEE~TTHHHHTTT~~~TTT~S~STTHHHHHHHHHTT~SS~~~~~EEE~TTSSGGG~~~HHHHHHHHHHHHHTT~~EE~~EEE~~~~B~TTS~B~~~~HHHHHHHHHHHTTT~SS~~HHHHHHHHT~~~~TT~BHHHHHHHHHHHHHTT~~SS~TTHHHHHHHHHHHHHHHHHTSSSS~~~HHHHHHHHHHHTSS~THHHHHS~HHHHHHHTTT~~GGGGGGS~HHHHHHHHHTTS~B~TTT~~B~~~HHHHHHHHHHHHTTTS~HHHHHHHHHHHHHHHTTTSEE~~HHHHHHTTSS~~~~~~EEEE~~~SSHHHHHHHHHHHHHHHTTT~EEEE~GGGS~~TT~EEGGGTEE~~~SHHHHHHHHHHHSTTSSTTSSS~~BEEEEETTBTTHHHHTTTT~SSS~GGG~~~SSEEEEEE~HHHHHHHHTT~EEE~B~TTTSTTHHHHHHH~HHHHHHHHHHHHH~TTS~~~EEEHHHHHHHHHHHHHHTS~EEEEEHHHHHHSSSB~TTTS~~~~~~TTS~~~~~~B~~SSTT~SS~B~~B~~EEEEEGGG~SSGGGHHHHHHHHHHHHHHHHHHS~~SSHHHHHHHHHT~~~EEEEE~HHHHHHHTT~~SSS~TTHHHHHHHHHHHHHHHHHHHHHHHHHH~~~TTGGGBGGGGT~~TTTSS~GGGGGT~~~~~~S~HHHHHHHHHHH~~SSS~~~~B~~~SHHHHHTT~~STTS~~SSTEEEEE~SSSEEEEE~TTTTT~SSS~~~TTTSS~STTHHHHHHHHHTT~SS~B~~~~EE~TTSSGGG~~~HHHHHHHHHHHHHTT~~EE~~~EE~~~~EEE~TTS~EEE~~HHHHHHHHHHHHTT~SS~~HHHHHHHHT~~~~TTEEHHHHHHHHHHHHHHT~BTTBTTHHHHHHHHHHHHHHHHHSSSSS~~~HHHHHHHHHHHTSS~THHHHHS~HHHHHHHTTT~~GGGGGGS~HHHHHHHHHTTS~B~TTT~~B~~~HHHHHHHHHHHHSTTS~HHHHHHHHHHHHHHHTTTSEE~~HHHHHHTTSS~~~~~~EEEE~~~SSHHHHHHHHHHHHHHHTTT~EEEE~GGGS~~TT~EEGGGTEE~~~SHHHHHHHHHHHSSSSSTTTSS~~BEEEEETTBTTHHHHTTSS~SSS~GGG~~TTSEEEEEE~HHHHHHHHTT~EEE~B~TTTSTTTTHHHHS~HHHHHHHHHHHHH~TTS~~~EEEHHHHHHHHHHHHHHTS~EEEEEHHHHHHSSSB~TTTS~~~~~~TTS~~~~~~B~~SSTT~SS~B~~B~~EEEEETTT~SSGGGHHHHHHHHHHHHHHHHHHS~~SSHHHHHHHHHH~~~EEEEE~HHHHHHHTT~~SSS~TTHHHHHHHHHHHHHHHHHHHHHHHHHH~~~TTGGGBGGGGT~~TTTSS~GGGGGT~~~~~~S~HHHHHHHHHHH~~SSS~~~~B~~~SHHHHHTT~~STTS~~SSTEEEEE~SSSEEEEE~TTHHHHTTT~~~TTTSS~STTHHHHHHHHHTT~SS~B~~~EEE~TTSSGGG~~BHHHHHHHHHHHHHTT~~EE~~EEE~~~~~~SS~~S~~~TTTS~SBSS~~~~S~~~S~~S~HHHHHHHHHHHHT~~~TTTS~~TTHHHHHHHS~HHHHHHHHHHHHHHHHHHHHTTTHHHHHHTTTB~~HHHHHHHHHHHHHHHHHHHHHHHHHHHH~S~THHHHHHHHH~HHHHHHHHHHHHHHHHHHHHHHHHHHH~SEEEEETTEEEEE~HHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHTT~SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSS~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSS~~~TT~~HHHHHHHHHHHHHHHHHHHT~~~~S~~~~~S~GGGGGG~~~~~SHHHHT~~~~~~SS~~S~~~TTTS~SBSS~~~~S~~~S~~S~HHHHHHHHHHHHT~~~TTTS~~STHHHHHHHS~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTB~~HHHHHHHHHHHHHHHHHHHHHHHHHHHH~S~THHHHHHHHH~HHHHHHHHHHHHHHHHHHHHHHHHHHT~SEEEEETTEEEEE~HHHHHHHHHHHHHHHHHHHHTTTHHHHHHHHHHHHTT~SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSS~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS~~BTTB~HHHHHHHHHHHHHHHHHHHT~~~~S~~~~~S~GGGGSS~~~B~~~~~HHHHHT~~~~~~SS~~S~~~TTTS~SBSS~~~~S~~~S~~S~HHHHHHHHHHHHT~~~TTTS~~TTHHHHHHHS~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHB~~HHHHHHHHHHHHHHHHHHHHHHHHHHHH~S~THHHHHHHHH~HHHHHHHHHHHHHHHHHHHHHHHHHHT~SEEEEETTEEEEE~HHHHHHHHHHHHHHHHHHHHTTTHHHHHHHHHHHHTT~SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSS~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSTT~~~TT~~HHHHHHHHHHHHHHHHHHHT~~~~S~~~~~S~GGGHHHH~~~B~~~~SHHHHT~~~~~~SS~~S~~~TTTS~SBSS~~~~S~~~S~~S~HHHHHHHHHHHHT~~~GGGS~~STHHHHHHHS~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTB~~HHHHHHHHHHHHHHHHHHHHHHHHHHHH~S~THHHHHHHHH~HHHHHHHHHHHHHHHHHHHHHHHHHHT~SEEEEETTEEEEE~HHHHHHHHHHHHHHHHHHHHTTTHHHHHHHHHHHHTT~SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSS~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSS~~~SS~~HHHHHHHHHHHHHHHHHHHT~~~~S~~~~~S~GGGGGGS~~~~~~~~HHHHHT~~~

N L L V T K R D G S T E R I N L D K I H R V L D W A A E G L H N V S I S Q V E L R S H I Q F Y D G I K T S D I H E T I I K A A A D L I S R D A P D Y Q Y L A A R L A I F H L R K K A Y G Q F E P P A L Y D H V V K M V E M G K Y D N H L L E D Y T E E E F K Q M D T F I D H D R D M T F S Y A A V K Q L E G K Y L V Q N R V T G E I Y E S A Q F L Y I L V A A C L F S N Y P R E T R L Q Y V K R F Y D A V S T F K I S L P T P I M S G V R T P T R Q F S S C V L I E C G D S L D S I N A T S S A I V K Y V S Q R A G I G I N A G R I R A L G S P I R G G E A F H T G C I P F Y K H F Q T A V K S C S Q G G V R G G A A T L F Y P M W H L E V E S L L V L K N N R G V E G N R V R H M D Y G V Q I N K L M Y T R L L K G E D I T L F S P S D V P G L Y D A F F A D Q E E F E R L Y T K Y E K D D S I R K Q R V K A V E L F S L M M Q E R A S T G R I Y I Q N V D H C N T H S P F D P A I A P V R Q S N L C L E I A L P T K P L N D V N D E N G E I A L C T L S A F N L G A I N N L D E L E E L A I L A V R A L D A L L D Y Q D Y P I P A A K R G A M G R R T L G I G V I N F A Y Y L A K H G K R Y S D G S A N N L T H K T F E A I Q Y Y L L K A S N E L A K E Q G A C P W F N E T T Y A K G I L P I D T Y K K D L D T I A N E P L H Y D W E A L R E S I K T H G L R N S T L S A L M P S E T S S Q I S N A T N G I E P P R G Y V S I K A S K D G I L R Q V V P D Y E H L H D A Y E L L W E M P G N D G Y L Q L V G I M Q K F I D Q S I S A N T N Y D P S R F P S G K V P M Q Q L L K D L L T A Y K F G V K T L Y Y Q N T R D N L L V T K R D G S T E R I N L D K I H R V L D W A A E G L H N V S I S Q V E L R S H I Q F Y D G I K T S D I H E T I I K A A A D L I S R D A P D Y Q Y L A A R L A I F H L R K K A Y G Q F E P P A L Y D H V V K M V E M G K Y D N H L L E D Y T E E E F K Q M D T F I D H D R D M T F S Y A A V K Q L E G K Y L V Q N R V T G E I Y E S A Q F L Y I L V A A C L F S N Y P R E T R L Q Y V K R F Y D A V S T F K I S L P T P I M S G V R T P T R Q F S S C V L I E C G D S L D S I N A T S S A I V K Y V S Q R A G I G I N A G R I R A L G S P I R G G E A F H T G C I P F Y K H F Q T A V K S C S Q G G V R G G A A T L F Y P M W H L E V E S L L V L K N N R G V E G N R V R H M D Y G V Q I N K L M Y T R L L K G E D I T L F S P S D V P G L Y D A F F A D Q E E F E R L Y T K Y E K D D S I R K Q R V K A V E L F S L M M Q E R A S T G R I Y I Q N V D H C N T H S P F D P A I A P V R Q S N L C L E I A L P T K P L N D V N D E N G E I A L C T L S A F N L G A I N N L D E L E E L A I L A V R A L D A L L D Y Q D Y P I P A A K R G A M G R R T L G I G V I N F A Y Y L A K H G K R Y S D G S A N N L T H K T F E A I Q Y Y L L K A S N E L A K E Q G A C P W F N E T T Y A K G I L P I D T Y K K D L D T I A N E P L H Y D W E A L R E S I K T H G L R N S T L S A L M P S E T S S Q I S N A T N G I E P P R G Y V S I K A S K D G I L R Q V V P D Y E H L H D A Y E L L W E M P G N D G Y L Q L V G I M Q K F I D Q S I S A N T N Y D P S R F P S G K V P M Q Q L L K D L L T A Y K F G V K T L Y Y Q N T R D G V T K R D G S T E R I N L D K I H R V L D W A A E G L H N V S I S Q V E L R S H I Q F Y D G I K T S D I H E T I I K A A A D L I S R D A P D Y Q Y L A A R L A I F H L R K K A Y G Q F E P P A L Y D H V V K M V E M G K Y D N H L L E D Y T E E E F K Q M D T F I D H D R D M T F S Y A A V K Q L E G K Y L V Q N R V T G E I Y E S A Q F L Y I L V A A C L F S N Y P R E T R L Q Y V K R F Y D A V S T F K I S L P T P I M S G V R T P T R Q F S S C V L I E C G D S L D S I N A T S S A I V K Y V S Q R A G I G I N A G R I R A L G S P I R G G E A F H T G C I P F Y K H F Q T A V K S C S Q G G V R G G A A T L F Y P M W H L E V E S L L V L K N N R G V E G N R V R H M D Y G V Q I N K L M Y T R L L K G E D I T L F S P S D V P G L Y D A F F A D Q E E F E R L Y T K Y E K D D S I R K Q R V K A V E L F S L M M Q E R A S T G R I Y I Q N V D H C N T H S P F D P A I A P V R Q S N L C L E I A L P T K P L N D V N D E N G E I A L C T L S A F N L G A I N N L D E L E E L A I L A V R A L D A L L D Y Q D Y P I P A A K R G A M G R R T L G I G V I N F A Y Y L A K H G K R Y S D G S A N N L T H K T F E A I Q Y Y L L K A S N E L A K E Q G A C P W F N E T T Y A K G I L P I D T Y K K D L D T I A N E P L H Y D W E A L R E S I K T H G L R N S T L S A L M P S E T S S Q I S N A T N G I E P P R G Y V S I K A S K D G I L R Q V V P D Y E H L H D A Y E L L W E M P G N D G Y L Q L V G I M Q K F I D Q S I S A N T N Y D P S R F P S G K V P M Q Q L L K D L L T A Y K F G V K T L Y Y Q N T R D G L L V T K R D G S T E R I N L D K I H R V L D W A A E G L H N V S I S Q V E L R S H I Q F Y D G I K T S D I H E T I I K A A A D L I S R D A P D Y Q Y L A A R L A I F H L R K K A Y G Q F E P P A L Y D H V V K M V E M G K Y D N H L L E D Y T E E E F K Q M D T F I D H D R D M T F S Y A A V K Q L E G K Y L V Q N R V T G E I Y E S A Q F L Y I L V A A C L F S N Y P R E T R L Q Y V K R F Y D A V S T F K I S L P T P I M S G V R T P T R Q F S S C V L I E C G D S L D S I N A T S S A I V K Y V S Q R A G I G I N A G R I R A L G S P I R G G E A F H T G C I P F Y K H F Q T A V K S C S Q G G V R G G A A T L F Y P M W H L E V E S L L V L K N N R G V E G N R V R H M D Y G V Q I N K L M Y T R L L K G E D I T L F S P S D V P G L Y D A F F A D Q E E F E R L Y T K Y E K D D S I R K Q R V K A V E L F S L M M Q E R A S T G R I Y I Q N V D H C N T H S P F D P A I A P V R Q S N L C L E I A L P T K P L N D V N D E N G E I A L C T L S A F N L G A I N N L D E L E E L A I L A V R A L D A L L D Y Q D Y P I P A A K R G A M G R R T L G I G V I N F A Y Y L A K H G K R Y S D G S A N N L T H K T F E A I Q Y Y L L K A S N E L A K E Q G A C P W F N E T T Y A K G I L P I D T Y K K D L D T I A N E P L H Y D W E A L R E S I K T H G L R N S T L S A L M P S E T S S Q I S N A T N G I E P P R G Y V S I K A S K D G I L R Q V V P D Y E H L H D A Y E L L W E M P G N D G Y L Q L V G I M Q K F I D Q S I S A N T N Y D P S R F P S G K V P M Q Q L L K D L L T A Y K F G V K T L Y Y Q N T R D G A Y T T F S Q T K N D Q L K E P M F F G Q P V N V A R Y D Q Q K Y D I F E K L I E K Q L S F F W R P E E V D V S R D R I D Y Q A L P E H E K H I F I S N L K Y Q T L L D S I Q G R S P N V A L L P L I S I P E L E T W V E T W A F S E T I H S R S Y T H I I R N I V N D P S V V F D D I V T N E Q I Q K R A E G I S S Y Y D E L I E M T S Y W H L L G E G T H T V N G K T V T V S L R E L K K K L Y L C L M S V N A L E A I R F Y V S F A C S F A F A E R E L M E G N A K I I R L I A R D E A L H L T G T Q H M L N L L R S G A D D P E M A E I A E E C K Q E C Y D L F V Q A A Q Q E K D W A D Y L F R D G S M I G L N K D I L C Q Y V E Y I T N I R M Q A V G L D L P F Q T R S N P I P W I N T W L S E V D T D D L S N F Q L A Y T T F S Q T K N D Q L K E P M F F G Q P V N V A R Y D Q Q K Y D I F E K L I E K Q L S F F W R P E E V D V S R D R I D Y Q A L P E H E K H I F I S N L K Y Q T L L D S I Q G R S P N V A L L P L I S I P E L E T W V E T W A F S E T I H S R S Y T H I I R N I V N D P S V V F D D I V T N E Q I Q K R A E G I S S Y Y D E L I E M T S Y W H L L G E G T H T V N G K T V T V S L R E L K K K L Y L C L M S V N A L E A I R F Y V S F A C S F A F A E R E L M E G N A K I I R L I A R D E A L H L T G T Q H M L N L L R S G A D D P E M A E I A E E C K Q E C Y D L F V Q A A Q Q E K D W A D Y L F R D G S M I G L N K D I L C Q Y V E Y I T N I R M Q A V G L D L P F Q T R S N P I P W I N T W L V Q I D S E V D T D D L S N F Q L A Y T T F S Q T K N D Q L K E P M F F G Q P V N V A R Y D Q Q K Y D I F E K L I E K Q L S F F W R P E E V D V S R D R I D Y Q A L P E H E K H I F I S N L K Y Q T L L D S I Q G R S P N V A L L P L I S I P E L E T W V E T W A F S E T I H S R S Y T H I I R N I V N D P S V V F D D I V T N E Q I Q K R A E G I S S Y Y D E L I E M T S Y W H L L G E G T H T V N G K T V T V S L R E L K K K L Y L C L M S V N A L E A I R F Y V S F A C S F A F A E R E L M E G N A K I I R L I A R D E A L H L T G T Q H M L N L L R S G A D D P E M A E I A E E C K Q E C Y D L F V Q A A Q Q E K D W A D Y L F R D G S M I G L N K D I L C Q Y V E Y I T N I R M Q A V G L D L P F Q T R S N P I P W I N T W L V Q I D S E V D T D D L S N F Q L A Y T T F S Q T K N D Q L K E P M F F G Q P V N V A R Y D Q Q K Y D I F E K L I E K Q L S F F W R P E E V D V S R D R I D Y Q A L P E H E K H I F I S N L K Y Q T L L D S I Q G R S P N V A L L P L I S I P E L E T W V E T W A F S E T I H S R S Y T H I I R N I V N D P S V V F D D I V T N E Q I Q K R A E G I S S Y Y D E L I E M T S Y W H L L G E G T H T V N G K T V T V S L R E L K K K L Y L C L M S V N A L E A I R F Y V S F A C S F A F A E R E L M E G N A K I I R L I A R D E A L H L T G T Q H M L N L L R S G A D D P E M A E I A E E C K Q E C Y D L F V Q A A Q Q E K D W A D Y L F R D G S M I G L N K D I L C Q Y V E Y I T N I R M Q A V G L D L P F Q T R S N P I P W I N T W L V S I D S E V D T D D L S N F Q L

AH

UNSTRUCTURED

3IQO

SELEKAVVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDSDGDGECDFQEFMAFVAMITTACHEFFSELEKAVVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDSDGDGECDFQEFMAFVAMITTACHEFF

~HHHHHHHHHHHHHHHHHTSSSSTTSB~HHHHHHHHHHH~TTTS~~~~SHHHHHHHHHHE~TTSSSSB~HHHHHHHHHHHHHHHHHH~~HHHHHHHHHHHHHHHHHTSSSSTTSB~HHHHHHHHHHH~TTTS~~~~SHHHHHHHHHHH~TTSSSSB~HHHHHHHHHHHHHHHHHH~

S E L E K A V V A L I D V F H Q Y S G R E G D K H K L K K S E L K E L I N N E L S H F L E E I K E Q E V V D K V M E T L D S D G D G E C D F Q E F M A F V A M I T T A C H E F F S E L E K A V V A L I D V F H Q Y S G R E G D K H K L K K S E L K E L I N N E L S H F L E E I K E Q E V V D K V M E T L D S D G D G E C D F Q E F M A F V A M I T T A C H E F F

AH

BEND

4WRU

RPLSELVERGWAAALEPVADQVAHMGQFLRAEIAAGRRYLPAGSNVLRAFTFPFDNVRVLIVGQDPYPTPGHAVGLSFSVAPDVRPWPRSLANIFDEYTADLGYPLPSNGDLTPWAQRGVLLLNRVLTVRPSNPASHRGKGWEAVTECAIRALAARAAPLVAILWGRDASTLKPMLAAGNCVAIESPHPSPLSASRGFFGSRPFSRANELLVGMGAEPIDWRLP

~~GGGTS~HHHHHHTGGGHHHHHHHHHHHHHHHHTT~~~BS~GGGTTGGGGS~GGG~~EEEEESS~~~STTT~~SSTT~~~TT~~S~~HHHHHHHHHHHHHH~~~~~SSS~~HHHHHTTEEEEESS~~BBTTBTTTTTTSSHHHHHHHHHHHHHHT~S~EEEEEESTTHHHHGGGG~STTEEEEEE~~~STTTGGGTTTT~~HHHHHHHHHHHTT~~~~~~~~~

R P L S E L V E R G W A A A L E P V A D Q V A H M G Q F L R A E I A A G R R Y L P A G S N V L R A F T F P F D N V R V L I V G Q D P Y P T P G H A V G L S F S V A P D V R P W P R S L A N I F D E Y T A D L G Y P L P S N G D L T P W A Q R G V L L L N R V L T V R P S N P A S H R G K G W E A V T E C A I R A L A A R A A P L V A I L W G R D A S T L K P M L A A G N C V A I E S P H P S P L S A S R G F F G S R P F S R A N E L L V G M G A E P I D W R L P

AH

UNSTRUCTURED

3I3N

YFQSEAEDFECSSHCSELSWRQNEQRRQGLFCDITLCFGREFRAHRSVLAAATEYFTPLLSGRVERKWSSEPGPEPDTVEAVIEYYTGRIRVSTGSVHEVLELADRFLLIRLKEFCGEFLKKKLHLSNCVAIHSLAHYTLSQLALKAADIRRNFHKVIQDEEFYTLPFHLIRDWLSDLEITVDSEEVLFETVLKWVQRNAEERERYFEELFKLLRLSQKPTYLTRHVKPERLVANNEVCVKLVADAVERHALRAENSEAEDFECSSHCSELSWRQNEQRRQGLFCDITLCFGGREFRAHRSVLAAATEYFTPLLSGQFSESRSGRVERKWSSEPGPEPDTVEAVIEYYTGRIRVSTGSVHEVLELADRFLLIRLKEFCGEFLKKKLHLSNCVAIHSLAHYTLSQLALKAADIRRNFHKVIQDEEFYTLPFHLIRDWLSDLEITVDSEEVLFETVLKWVQRNAEERERYFEELFKLLRLSQKPTYLTRHVKPERLVANNEVCVKLVADAVERHALRAE

~~~~~EEEEE~TTHHHHHHHHHHHHHHHTTT~~EEEE~~~EEEE~HHHHHHH~TTSGGG~~~EE~~~~SSTT~S~HHHHHHHHH~~~SEEEEETTTHHHHHHHHHHTT~HHHHHHHHHHHHHH~~TTTHHHHHHHH~~~~HHHHHHHH~~~TTHHHHTTSSGGGGS~HHHHHHHHT~SS~~~S~HHHHHHHHHHHHHTTHHHHTTTHHHHHTTS~TT~~HHHHHHTTTTSHHHHT~HHHHHHHHHHHHHHHHTT~~~~EEEEE~SSHHHHHHHHHHHHHHTTTT~~EEEE~~~~EEEE~HHHHHHH~TTSGGGTTT~S~~~TT~EE~~~~SSTT~S~HHHHHHHHH~~~SEEEEETTTHHHHHHHHHHTT~HHHHHHHHHHHHHH~~TTTHHHHHHHH~~~~HHHHHHHH~~~TTHHHHTTSSSGGGS~HHHHHHHHT~SS~~~S~HHHHHHHHHHHHHT~HHHHTTTHHHHHTTS~TT~~HHHHHHTTTTSHHHHS~HHHHHHHHHHHHHHHHT~~

Y F Q S E A E D F E C S S H C S E L S W R Q N E Q R R Q G L F C D I T L C F G R E F R A H R S V L A A A T E Y F T P L L S G R V E R K W S S E P G P E P D T V E A V I E Y Y T G R I R V S T G S V H E V L E L A D R F L L I R L K E F C G E F L K K K L H L S N C V A I H S L A H Y T L S Q L A L K A A D I R R N F H K V I Q D E E F Y T L P F H L I R D W L S D L E I T V D S E E V L F E T V L K W V Q R N A E E R E R Y F E E L F K L L R L S Q K P T Y L T R H V K P E R L V A N N E V C V K L V A D A V E R H A L R A E N S E A E D F E C S S H C S E L S W R Q N E Q R R Q G L F C D I T L C F G G R E F R A H R S V L A A A T E Y F T P L L S G Q F S E S R S G R V E R K W S S E P G P E P D T V E A V I E Y Y T G R I R V S T G S V H E V L E L A D R F L L I R L K E F C G E F L K K K L H L S N C V A I H S L A H Y T L S Q L A L K A A D I R R N F H K V I Q D E E F Y T L P F H L I R D W L S D L E I T V D S E E V L F E T V L K W V Q R N A E E R E R Y F E E L F K L L R L S Q K P T Y L T R H V K P E R L V A N N E V C V K L V A D A V E R H A L R A E

AH

UNSTRUCTURED

2EPV

GSSGSSGSGEKPYECNECGKAFIWKSLLIVHERTHAGVSGPSSG

~~~~~~~~~~~SEE~SSS~~EESSHHHHHHHHGGGSS~S~~~~~

G S S G S S G S G E K P Y E C N E C G K A F I W K S L L I V H E R T H A G V S G P S S G

UNSTRUCTURED

BEND

3NP0

SSQIRQNYSTEVEAAVNRLVNLYLRASYTYLSLGFYFDRDDVALCGVCAFFHELAEEKREGAERLLKMQNQRGGRALFQDLQKPSQDEWGTTLDAMKAAIVLEKSLNQALLDLHALGSAQADPHLCDFLESHFLDEEVKLIKKMGDHLTNIQRLVGSQAGLGEYLFERLTLKHD

~~S~~~S~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHTSTTT~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHT~~~~~~~~~~~S~S~~~SHHHHHHHHHHHHHHHHHHHHHHHHHHHETT~HHHHHHHHTTTHHHHHHHHHHHHHHHHHHHHHHTT~HHHHHHHHHHHTS~~~

S S Q I R Q N Y S T E V E A A V N R L V N L Y L R A S Y T Y L S L G F Y F D R D D V A L C G V C A F F H E L A E E K R E G A E R L L K M Q N Q R G G R A L F Q D L Q K P S Q D E W G T T L D A M K A A I V L E K S L N Q A L L D L H A L G S A Q A D P H L C D F L E S H F L D E E V K L I K K M G D H L T N I Q R L V G S Q A G L G E Y L F E R L T L K H D

AH

UNSTRUCTURED

3LZ6

KFRPEMLQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAHYIAGSMEDMTFAEEFVAEAGNLMGGLDMLILNHVLYNRLTFFHGEIDNVRKSMEVNFHSFVVLSVAAMPMLMQSQGSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTLRSEFLVNKVNVSITLCILGLIDTETAIKATSGIYLGPASPKEECALEIIKGTALRQDEMYYVGSRWVPYLLGNPGRKIMEFLSAAEYNWDNKFRPEMLQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAHYIAGSMEDMTFAEEFVAEAGNLMGGLDMLILNHVLYNRLTFFHGEIDNVRKSMEVNFHSFVVLSVAAMPMLMQSQGSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTLRSEFLVNKVNVSITLCILGLIDTETAIKATSGIYLGPASPKEECALEIIKGTALRQDEMYYVGSRWVPYLLGNPGRKIMEFLSAAEYNWDNKFRPEMLQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAHYIAGSMEDMTFAEEFVAEAGNLMGGLDMLILNHVLYNRLTFFHGEIDNVRKSMEVNFHSFVVLSVAAMPMLMQSQGSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTLRSEFLVNKVNVSITLCILGLIDTETAIKATSGIYLGPASPKEECALEIIKGTALRQDEMYYVGSRWVPYLLGNPGRKIMEFLSAAEYNWDNKFRPEMLQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAHYIAGSMEDMTFAEEFVAEAGNLMGGLDMLILNHVLYNRLTFFHGEIDNVRKSMEVNFHSFVVLSVAAMPMLMQSQGSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTLRSEFLVNKVNVSITLCILGLIDTETAIKATSGIYLGPASPKEECALEIIKGTALRQDEMYYVGSRWVPYLLGNPGRKIMEFLSAAEYNWDN

~~~GGGGTT~EEEESS~SSHHHHHHHHHHHHTT~EEEEEES~HHHHHHHHHHHHHHT~SEEEEEE~~TT~HHHHHHHHHHHHHHHTS~SEEEE~~~~~~~~~~~~S~HHHHHHHHHHHTHHHHHHHHHHHHHHHHHT~EEEEEEEGGGTS~~TT~HHHHHHHHHHHHHHHHHHHHHHHTT~~~EEEEEEE~~B~~HHHHHHHTTTB~~~~B~HHHHHHHHHHHHHTT~SEEEESS~SSHHHHHS~HHHHHHHHHHHTTB~S~~~~~GGGGTT~EEEESS~SSHHHHHHHHHHHHTT~EEEEEES~HHHHHHHHHHHHHHT~SEEEEEE~~TT~HHHHHHHHHHHHHHHTS~SEEEE~~~~~~~~~~~SS~HHHHHHHHHHHTHHHHHHHHHHHHHHHHHT~EEEEEEEGGGTS~~TT~HHHHHHHHHHHHHHHHHHHHHHHTT~~~EEEEEEE~~B~~HHHHHHHTTTB~~~~B~HHHHHHHHHHHHHTT~SEEEE~S~TTHHHHHS~HHHHHHHHHHHTTB~S~~~~~GGGGTT~EEEESS~SSHHHHHHHHHHHHTT~EEEEEES~HHHHHHHHHHHHHTT~SEEEEEE~~TT~HHHHHHHHHHHHHHHTS~SEEEE~~~~~~~~~~~SS~HHHHHHHHHHHTHHHHHHHHHHHHHHHHHT~EEEEEEEGGGTS~~TT~HHHHHHHHHHHHHHHHHHHHHHHHT~~~EEEEEEE~~B~~HHHHHHHTTTB~~~~B~HHHHHHHHHHHHHTT~SEEEESS~SSHHHHHS~HHHHHHHHHHHTTB~TT~~~~GGGGTT~EEEESS~SSHHHHHHHHHHHHTT~EEEEEES~HHHHHHHHHHHHHHT~SEEEEEE~~TT~HHHHHHHHHHHHHHHTS~SEEEE~~~~~~~~~~~~~~HHHHHHHHHHHTHHHHHHHHHHHHHHHHHT~EEEEEEEGGGTS~~TT~HHHHHHHHHHHHHHHHHHHHHHHTT~~~EEEEEEE~~B~~HHHHHHHTTTB~~~~B~HHHHHHHHHHHHHTT~SEEEESS~SSHHHHHS~HHHHHHHHHHGGGB~TT~

K F R P E M L Q G K K V I V T G A S K G I G R E I A Y H L A K M G A H V V V T A R S K E A L Q K V V A R C L E L G A A S A H Y I A G S M E D M T F A E E F V A E A G N L M G G L D M L I L N H V L Y N R L T F F H G E I D N V R K S M E V N F H S F V V L S V A A M P M L M Q S Q G S I A V V S S V A G K I T Y P L I A P Y S A S K F A L D G F F S T L R S E F L V N K V N V S I T L C I L G L I D T E T A I K A T S G I Y L G P A S P K E E C A L E I I K G T A L R Q D E M Y Y V G S R W V P Y L L G N P G R K I M E F L S A A E Y N W D N K F R P E M L Q G K K V I V T G A S K G I G R E I A Y H L A K M G A H V V V T A R S K E A L Q K V V A R C L E L G A A S A H Y I A G S M E D M T F A E E F V A E A G N L M G G L D M L I L N H V L Y N R L T F F H G E I D N V R K S M E V N F H S F V V L S V A A M P M L M Q S Q G S I A V V S S V A G K I T Y P L I A P Y S A S K F A L D G F F S T L R S E F L V N K V N V S I T L C I L G L I D T E T A I K A T S G I Y L G P A S P K E E C A L E I I K G T A L R Q D E M Y Y V G S R W V P Y L L G N P G R K I M E F L S A A E Y N W D N K F R P E M L Q G K K V I V T G A S K G I G R E I A Y H L A K M G A H V V V T A R S K E A L Q K V V A R C L E L G A A S A H Y I A G S M E D M T F A E E F V A E A G N L M G G L D M L I L N H V L Y N R L T F F H G E I D N V R K S M E V N F H S F V V L S V A A M P M L M Q S Q G S I A V V S S V A G K I T Y P L I A P Y S A S K F A L D G F F S T L R S E F L V N K V N V S I T L C I L G L I D T E T A I K A T S G I Y L G P A S P K E E C A L E I I K G T A L R Q D E M Y Y V G S R W V P Y L L G N P G R K I M E F L S A A E Y N W D N K F R P E M L Q G K K V I V T G A S K G I G R E I A Y H L A K M G A H V V V T A R S K E A L Q K V V A R C L E L G A A S A H Y I A G S M E D M T F A E E F V A E A G N L M G G L D M L I L N H V L Y N R L T F F H G E I D N V R K S M E V N F H S F V V L S V A A M P M L M Q S Q G S I A V V S S V A G K I T Y P L I A P Y S A S K F A L D G F F S T L R S E F L V N K V N V S I T L C I L G L I D T E T A I K A T S G I Y L G P A S P K E E C A L E I I K G T A L R Q D E M Y Y V G S R W V P Y L L G N P G R K I M E F L S A A E Y N W D N

AH

UNSTRUCTURED

4BLS

MIHLYDAKSFAKLRAAQYAAFHTDAPGSWFDHTSGVLESVEDGTPVLAIGVESGDAIVFDKNAQRIVAYKEKSVKAEDGSVSVVQVENGFMKQGHRGWLVDLTGELVGCSPVVAEFGGHRYASGMVIVTGKGNSGKTPLVHALGEALGGKDKYATVRFGEPLSGYNTDFNVFVDDIARAMLQHRVIVIDSLKNVIISRGAFDLLSDIGAMAASRGCVVIASLNPTSNDDKIVELVKEASRSNSTSLVISTDVDGEWQVLTRTGEGLARLTHTLQTSYGEHSVLTIHTSQTVIKNDELESVLRMIHLYDAKSFAKLRAAQYAAFHTDAPGSWFDHTSGVLESVEDGTPVLAIGVESGDAIVFDKNAQRIVAYKEKSVKAEDGSVSVVQVENGFMKQGHRGWLVDLTGELVGCSPVVAEFGGHRYASGMVIVTGKGNSGKTPLVHALGEALGGKDKYATVRFGEPLSGYNTDFNVFVDDIARAMLQHRVIVIDSLKNVIISRGAFDLLSDIGAMAASRGCVVIASLNPTSNDDKIVELVKEASRSNSTSLVISTDVDGEWQVLTRTGEGLARLTHTLQTSYGEHSVLTIHTSQTVIKNDELESVLRRMIHLYDAKSFAKLRAAQYAAFHTDAPGSWFDHTSGVLESVEDGTPVLAIGVESGDAIVFDKNAQRIVAYKEKSVKAEDGSVSVVQVENGFMKQGHRGWLVDLTGELVGCSPVVAEFGGHRYASGMVIVTGKGNSGKTPLVHALGEALGGKDKYATVRFGEPLSGYNTDFNVFVDDIARAMLQHRVIVIDSLKNVIISRGAFDLLSDIGAMAASRGCVVIASLNPSNDDKIVELVKEASRSNSTSLVISTDVDGEWQVLTRTGEGLARLTHTLQTSYGEHSVLTIHTSQTVIKNDELESVLRR

~~EEE~HHHHHHHHHHHHHHHHTS~TTHHHHHHHHHHHHS~TT~~~EEEE~TTS~EEEE~TTS~B~S~EEEEEEE~TTS~EEEEEEETTEEEES~SEESS~SSTT~~S~~~EEEEETTEEEESEEEEEE~SSS~~HHHHHHHHHHHHHTTS~~EEEE~S~SSTT~~~~HHHHHHHHHHHHHH~SEEEEE~~TTT~~~HHHHHHHHHHHHHHHHHT~EEEEE~~~~~~~HHHHHHHHHHHHTT~SEEEEE~SSTT~EEEEEE~STT~~EEEEEE~EEE~GGG~EEE~~~~EEE~HHHHHHHT~~~EEE~HHHHHHHHHHHHHHHHTS~TTHHHHHHHHHHHHS~TT~~~EEEE~TTS~EEEE~TTS~B~S~EEEEEEE~TTS~EEEEEEETTEEEES~SEESS~SSTT~~S~~~EEEEETTEEEESEEEEEE~SSSS~HHHHHHHHHHHHHTTS~EEEEE~S~SSTT~~~~HHHHHHHHHHHHHH~SEEEEE~~TTT~~~HHHHHHHHHHHHHHHHHT~EEEEE~~~~S~~HHHHHHHHHHHHTT~SEEEEE~SSTT~EEEEEE~STT~~EEEEEE~EEE~GGG~EEE~~~~EEE~HHHHHHHT~~~~~~~~HHHHHHHHHHHHHHHHTS~TTHHHHHHHHHHHHS~TT~~~EEEE~TTS~EEEE~TTS~B~S~EEEEEEE~TTS~EEEEEEETTEEEES~SEESS~SSTT~~S~~~EEEEETTEEEESEEEEEE~SSSS~HHHHHHHHHHHHHTTS~EEEEE~S~SSTT~~~~HHHHHHHHHHHHHH~SEEEEE~~TTT~~~HHHHHHHHHHHHHHHHHT~EEEEE~~~~~~HHHHHHHHHHHHTT~SEEEEE~SSTT~EEEEEE~STT~~EEEEEE~EEE~GGG~EEE~~~~EEE~HHHHHHHT~~

M I H L Y D A K S F A K L R A A Q Y A A F H T D A P G S W F D H T S G V L E S V E D G T P V L A I G V E S G D A I V F D K N A Q R I V A Y K E K S V K A E D G S V S V V Q V E N G F M K Q G H R G W L V D L T G E L V G C S P V V A E F G G H R Y A S G M V I V T G K G N S G K T P L V H A L G E A L G G K D K Y A T V R F G E P L S G Y N T D F N V F V D D I A R A M L Q H R V I V I D S L K N V I I S R G A F D L L S D I G A M A A S R G C V V I A S L N P T S N D D K I V E L V K E A S R S N S T S L V I S T D V D G E W Q V L T R T G E G L A R L T H T L Q T S Y G E H S V L T I H T S Q T V I K N D E L E S V L R M I H L Y D A K S F A K L R A A Q Y A A F H T D A P G S W F D H T S G V L E S V E D G T P V L A I G V E S G D A I V F D K N A Q R I V A Y K E K S V K A E D G S V S V V Q V E N G F M K Q G H R G W L V D L T G E L V G C S P V V A E F G G H R Y A S G M V I V T G K G N S G K T P L V H A L G E A L G G K D K Y A T V R F G E P L S G Y N T D F N V F V D D I A R A M L Q H R V I V I D S L K N V I I S R G A F D L L S D I G A M A A S R G C V V I A S L N P T S N D D K I V E L V K E A S R S N S T S L V I S T D V D G E W Q V L T R T G E G L A R L T H T L Q T S Y G E H S V L T I H T S Q T V I K N D E L E S V L R R M I H L Y D A K S F A K L R A A Q Y A A F H T D A P G S W F D H T S G V L E S V E D G T P V L A I G V E S G D A I V F D K N A Q R I V A Y K E K S V K A E D G S V S V V Q V E N G F M K Q G H R G W L V D L T G E L V G C S P V V A E F G G H R Y A S G M V I V T G K G N S G K T P L V H A L G E A L G G K D K Y A T V R F G E P L S G Y N T D F N V F V D D I A R A M L Q H R V I V I D S L K N V I I S R G A F D L L S D I G A M A A S R G C V V I A S L N P S N D D K I V E L V K E A S R S N S T S L V I S T D V D G E W Q V L T R T G E G L A R L T H T L Q T S Y G E H S V L T I H T S Q T V I K N D E L E S V L R R

AH

BS

4K43

TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCTTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKC

~~~EEEEE~SSEEEEEETT~SS~SEEEE~~EEE~~~S~EESHHHHHTTTTSEEE~TTGGGS~~~HHHHHHHHHHHHHTTT~~~GGGS~EEEEE~TT~~HHHHHHHHHHHHHTT~~SEEEEEEHHHHHHHHHT~SSEEEEEE~SS~EEEEEEETTEE~GGG~EEE~~~HHHHHHHHHHHHHHHT~~~~SHHHHHHHHHHHHHH~~~~SSHHHHHHHHHH~SSS~EEEE~TTS~EEEE~THHHHTGGGGT~GGGGT~~S~~HHHHHHHHHTTS~GGGHHHHHT~EEEESGGGGSTTHHHHHHHHHHHHS~TT~~~~EE~~TTTTSHHHHHHHHHHT~TTTGGG~EEHHHHHHH~GGGHHHH~~~~EEEEE~SSEEEEEETT~SS~SEEEE~~EEE~~~S~EESHHHHHTTTTSEEE~TTGGGS~~~HHHHHHHHHHHHHTTT~~~GGGS~EEEEE~TT~~HHHHHHHHHHHHHTT~~SEEEEEEHHHHHHHHHT~SSEEEEEE~SS~EEEEEEETTEE~GGG~EEE~~~HHHHHHHHHHHHHHHT~~~~SHHHHHHHHHHHHHH~~~~SSHHHHHHHHHH~SSS~EEEE~TTS~EEEE~THHHHTGGGGT~GGGGT~~S~~HHHHHHHHHTTS~GGGHHHHHT~EEEESGGGGSTTHHHHHHHHHHHHS~TT~~~~EE~~TTTTSHHHHHHHHHHT~TTTGGG~EEHHHHHHH~GGGHHHH~

T T A L V C D N G S G L V K A G F A G D D A P R A V F P S I V G R P Q K D S Y V G D E A Q S K R G I L T L K Y P I E H G I I T N W D D M E K I W H H T F Y N E L R V A P E E H P T L L T E A P L N P K A N R E K M T Q I M F E T F N V P A M Y V A I Q A V L S L Y A S G R T T G I V L D S G D G V T H N V P I Y E G Y A L P H A I M R L D L A G R D L T D Y L M K I L T E R G Y S F V T T A E R E I V R D I K E K L C Y V A L D F E N E M A T A A S S S S L E K S Y E L P D G Q V I T I G N E R F R C P E T L F Q P S F I G M E S A G I H E T T Y N S I M K C D I D I R K D L Y A N N V M S G G T T M Y P G I A D R M Q K E I T A L A P S T M K I K I I A P P E R K Y S V W I G G S I L A S L S T F Q Q M W I T K Q E Y D E A G P S I V H R K C T T A L V C D N G S G L V K A G F A G D D A P R A V F P S I V G R P Q K D S Y V G D E A Q S K R G I L T L K Y P I E H G I I T N W D D M E K I W H H T F Y N E L R V A P E E H P T L L T E A P L N P K A N R E K M T Q I M F E T F N V P A M Y V A I Q A V L S L Y A S G R T T G I V L D S G D G V T H N V P I Y E G Y A L P H A I M R L D L A G R D L T D Y L M K I L T E R G Y S F V T T A E R E I V R D I K E K L C Y V A L D F E N E M A T A A S S S S L E K S Y E L P D G Q V I T I G N E R F R C P E T L F Q P S F I G M E S A G I H E T T Y N S I M K C D I D I R K D L Y A N N V M S G G T T M Y P G I A D R M Q K E I T A L A P S T M K I K I I A P P E R K Y S V W I G G S I L A S L S T F Q Q M W I T K Q E Y D E A G P S I V H R K C

AH

BS

2MBK

WLITGTEASCENEGEVLHIPNITDNPCISCVCLNQKAECKQEKCAPLAEDCALVVKQTGACCEKCKG

~~~~~S~~~~SSTTS~~~~HHHHTSTTEE~~EETTEE~~EE~~~~~SSSS~~~S~~~TT~S~~~~~~

W L I T G T E A S C E N E G E V L H I P N I T D N P C I S C V C L N Q K A E C K Q E K C A P L A E D C A L V V K Q T G A C C E K C K G

UNSTRUCTURED

BEND

3TKW

PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEIAGHKAIGTVLVGPTPVNIIGRNLLTQIGATLNFSFNFPQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEIAGHKAIGTVLVGPTPVNIIGRNLLTQIGATLNF

~EE~SSS~~EEEEEETTEEEEEEE~TT~SSEEE~S~~~SS~EEEEEEEETTEEEEEEEEEEEEEEETTEEEEEEEEES~~SS~EE~HHHHGGGT~EEE~~~BTTBTTSSS~~EEEEEETTEEEEEEE~TT~SS~EE~S~~~SS~EEEEEEEETTEEEEEEEEEEEEEEETTEEEEEEEEES~~SS~EE~HHHHHHHT~EEE~

P Q I T L W K R P L V T I K I G G Q L K E A L L D T G A D D T V I E E M S L P G R W K P K M I G G I G G F I K V R Q Y D Q I I I E I A G H K A I G T V L V G P T P V N I I G R N L L T Q I G A T L N F S F N F P Q I T L W K R P L V T I K I G G Q L K E A L L D T G A D D T V I E E M S L P G R W K P K M I G G I G G F I K V R Q Y D Q I I I E I A G H K A I G T V L V G P T P V N I I G R N L L T Q I G A T L N F

BS

UNSTRUCTURED

2AYW

IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN

~BS~EE~~TTSSTTEEEEESSSEEEEEEEEETTEEEE~GGG~~SS~EEEES~SSTTS~~S~~EEEEEEEEEE~TT~~TTT~TT~~EEEEESS~~~~BTTB~~~B~~SS~~~TT~EEEEEESS~~~SSS~~~~SS~EEEEEEB~~HHHHHHHSTTT~~TTEEEES~TTSS~B~~TT~TT~EEEETTEEEEEEEE~SSSS~TT~~EEEEEGGGSHHHHHHHHHH~

I V G G Y T C G A N T V P Y Q V S L N S G Y H F C G G S L I N S Q W V V S A A H C Y K S G I Q V R L G E D N I N V V E G N E Q F I S A S K S I V H P S Y N S N T L N N D I M L I K L K S A A S L N S R V A S I S L P T S C A S A G T Q C L I S G W G N T K S S G T S Y P D V L K C L K A P I L S D S S C K S A Y P G Q I T S N M F C A G Y L E G G K D S C Q G D S G G P V V C S G K L Q G I V S W G S G C A Q K N K P G V Y T K V C N Y V S W I K Q T I A S N

BS

UNSTRUCTURED

4UZS

KRRKHSWPQPLKGAESRLWYGGDYNPDQWPEEVWDDDIRLMKKAGVNLVSVGIFSWAKIEPEEGKYDFDWLDRAIDKLGKAGIAVDLASATASPPMWLTQAHPEVLWKDERGDTVWPGAREHWRPTSPVFREYALNLCRRMAEHYKGNPYVVAWHVSNEYGCHNRFDYSDDAMRAFQKWCKKRYKTIDAVNEAWGTAFWAQHMNDFSEIIPPRYIGDGNFMNPGKLLDYKRFSSDALKELYIAERDVLESITPGLPLTTNFMVSAGGSMLDYDDWGAEVDFVSNDHYFTPGEAHFDEVAYAASLMDGISRKEPWFQMEHSTSAVNWRPINYRAEPGSVVRDSLAQVAMGADAICYFQWRQSKAGAEKWHSSMVPHAGEDSQIFRDVCELGADLGRLSDEGLMGTKTVKSKVAVVFDYESQWATEYTANPTQQVDHWTEPLDWFRALADNGITADVVPVRSDWDSYEIAVLPCVYLLSEETSRRVREFVANGGKLFVTYYTGLSDENDHIWLGGYPGSIRDVVGVRVEEFAPMGNDMPGALDHLDLDNGTVAHDFADVITSTADTSTVLASYKAERWTGMNEVPAIVANGYGDGRTVYVGCRLGRQGLAKSLPAMLGSMGLSDLAGDGRVLRVERADAAAASHFEFVFNRTHEPVTVDVEGEAIAASLAHVDDGRATIDPTGVVVLRRRRKHSWPQPLKGAESRLWYGGDYNPDQWPEEVWDDDIRLMKKAGVNLVSVGIFSWAKIEPEEGKYDFDWLDRAIDKLGKAGIAVDLASATASPPMWLTQAHPEVLWKDERGDTVWPGAREHWRPTSPVFREYALNLCRRMAEHYKGNPYVVAWHVSNEYGCHNRFDYSDDAMRAFQKWCKKRYKTIDAVNEAWGTAFWAQHMNDFSEIIPPRYIGDGNFMNPGKLLDYKRFSSDALKELYIAERDVLESITPGLPLTTNFMVSAGGSMLDYDDWGAEVDFVSNDHYFTPGEAHFDEVAYAASLMDGISRKEPWFQMEHSTSAVNWRPINYRAEPGSVVRDSLAQVAMGADAICYFQWRQSKAGAEKWHSSMVPHAGEDSQIFRDVCELGADLGRLSDEGLMGTKTVKSKVAVVFDYESQWATEYTANPTQQVDHWTEPLDWFRALADNGITADVVPVRSDWDSYEIAVLPCVYLLSEETSRRVREFVANGGKLFVTYYTGLSDENDHIWLGGYPGSIRDVVGVRVEEFAPMGNDMPGALDHLDLDNGTVAHDFADVITSTADTSTVLASYKAERWTGMNEVPAIVANGYGDGRTVYVGCRLGRQGLAKSLPAMLGSMGLSGDGRVLRVERADSHFEFVFNRTHEPVTVDVEGEAIAASLAHVDDGRATIDPTGVVVLRRKRRKHSWPQPLKGAESRLWYGGDYNPDQWPEEVWDDDIRLMKKAGVNLVSVGIFSWAKIEPEEGKYDFDWLDRAIDKLGKAGIAVDLASATASPPMWLTQAHPEVLWKDERGDTVWPGAREHWRPTSPVFREYALNLCRRMAEHYKGNPYVVAWHVSNEYGCHNRFDYSDDAMRAFQKWCKKRYKTIDAVNEAWGTAFWAQHMNDFSEIIPPRYIGDGNFMNPGKLLDYKRFSSDALKELYIAERDVLESITPGLPLTTNFMVSAGGSMLDYDDWGAEVDFVSNDHYFTPGEAHFDEVAYAASLMDGISRKEPWFQMEHSTSAVNWRPINYRAEPGSVVRDSLAQVAMGADAICYFQWRQSKAGAEKWHSSMVPHAGEDSQIFRDVCELGADLGRLSDEGLMGTKTVKSKVAVVFDYESQWATEYTANPTQQVDHWTEPLDWFRALADNGITADVVPVRSDWDSYEIAVLPCVYLLSEETSRRVREFVANGGKLFVTYYTGLSDENDHIWLGGYPGSIRDVVGVRVEEFAPMGNDMPGALDHLDLDNGTVAHDFADVITSTADTSTVLASYKAERWTGMNEVPAIVANGYGDGRTVYVGCRLGRQGLAKSLPAMLGSMGLSDLAGDGRVLRVERADSHFEFVFNRTHEPVTVDVEGEAIAASLAHVDDGRATIDPTGVVVLRR

~~~~~~~~~~GGG~~~~~EEEEEE~GGGS~HHHHHHHHHHHHHHT~~EEEE~TT~HHHHSSBTTB~~~HHHHHHHHHHHHTT~EEEEE~STTS~~HHHHHH~GGGS~B~TT~~B~~SSSS~~S~TT~HHHHHHHHHHHHHHHHHHTT~TTEEEEE~SSSTTTTTS~~~SHHHHHHHHHHHHHHHSSHHHHHHHHTTTGGG~~~SSGGG~~~~~~~~TT~~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSTTS~EE~EE~~STT~~SS~HHHHGGGSSS~EEE~~~~SSTTHHHHHHHHHHHHHHHTTTS~EEEEE~~SS~~SSSSB~~~~~TTHHHHHHHHHHHTTEEEEEES~SB~~SSSTTTTS~~SB~TT~SSSHHHHHHHHHHHHHHHHHHTT~TT~EE~~~SEEEEE~HHHHHHHT~TTSSBTT~~TTHHHHHHHHHHHHTT~~~EEEETTSSGGGSSEEEE~S~~B~~HHHHHHHHHHHHTT~EEEEETT~S~B~TTS~B~~SSBSTTTHHHHTEEEEEEEE~~SSSTTS~~~EEETTS~EEEEEEEEEEEE~TTEEEEEEEE~~GGGS~TT~EEEEEEEETTEEEEEE~EE~HHHHHHHHHHHHHHHTT~GGG~~~TTEEEEEEE~GGG~SEEEEEEE~SSS~EEEE~~SEEEEEEEEEEETTEEEEEEEEEEEEE~~~~~~~~~~~TT~~~~~EEEEEE~GGGS~HHHHHHHHHHHHHHT~~EEEE~TT~HHHHSSBTTB~~~HHHHHHHHHHHHTT~EEEEE~S~SS~~HHHHHH~GGGS~B~TT~~B~~SSSS~~S~TT~HHHHHHHHHHHHHHHHHHTT~TTEEEEE~SSSTTTTTS~~~SHHHHHHHHHHHHHHHSSHHHHHHHTTTTGGG~~~SSGGG~~~~~~~~TT~~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSTTS~EE~EE~~~TT~~SS~HHHHGGGSSS~EEE~~~~~STTHHHHHHHHHHHHHHHTTTS~EEEEE~~SS~~SSSSB~~~~~TTHHHHHHHHHHHTTEEEEEES~SB~~SSSTTTTS~~SB~TT~SSSHHHHHHHHHHHHHHHHHHTT~TT~EE~~~SEEEEE~HHHHHHHT~TTSSBTT~~TTHHHHHHHHHHHHTT~~~EEEETTSSGGGSSEEEE~S~~B~~HHHHHHHHHHHHTT~EEEEESSSSSB~TTS~B~~SSBSTTTHHHHTEEEEEEEE~~SSSTT~~~~EEETTS~EEEEEEEEEEEE~TTEEEEEEEE~~GGGS~TT~EEEEEEEETTEEEEEE~EE~HHHHHHHHHHHHHHHTT~~~~TTEEEEEEE~~EEEEEEE~SSS~EEEE~~SEEEEEEEEEEETTEEEEEEEEEEEEE~~~~~~~~~~~~TT~~~~~EEEEEE~GGGS~GGGHHHHHHHHHHHT~~EEEE~TT~HHHHSSBTTB~~~HHHHHHHHHHHHTT~EEEEE~STTS~~HHHHHH~GGGS~B~TT~~B~~SSSS~~S~TT~HHHHHHHHHHHHHHHHHHTT~TTEEEEE~SSSTTTTTS~~~SHHHHHHHHHHHHHHHSSHHHHHHHTTTTGGG~~~SSGGG~~~S~~~~TT~~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSTTS~EE~EE~~~TT~~SS~HHHHGGGSSS~EEE~~~~~STTHHHHHHHHHHHHHHHTTTS~EEEEE~~SS~~SSSSB~~~~~TTHHHHHHHHHHHTTEEEEEES~SB~~SSSTTTTS~~SB~TT~SSSHHHHHHHHHHHHHHHHHHTT~TT~EE~~~SEEEEE~HHHHHHHT~TTSSBTT~~TTHHHHHHHHHHHHTT~~~EEEETTSSGGGSSEEEE~S~~B~~HHHHHHHHHHHHTT~EEEEETTSSSB~TTS~B~~SSBSTTTHHHHTEEEEEE~~~~SSSTTS~~~EEETTS~EEEEEEEEEEEE~TT~EEEEEEE~~GGGT~TT~EEEEEEEETTEEEEEE~EE~HHHHHHHHHHHHHHHTT~TTS~~~TTEEEEEEE~~EEEEEEE~SSS~EEEE~~SEEEEEEEEEEETTEEEEEEEEEEEEE~

K R R K H S W P Q P L K G A E S R L W Y G G D Y N P D Q W P E E V W D D D I R L M K K A G V N L V S V G I F S W A K I E P E E G K Y D F D W L D R A I D K L G K A G I A V D L A S A T A S P P M W L T Q A H P E V L W K D E R G D T V W P G A R E H W R P T S P V F R E Y A L N L C R R M A E H Y K G N P Y V V A W H V S N E Y G C H N R F D Y S D D A M R A F Q K W C K K R Y K T I D A V N E A W G T A F W A Q H M N D F S E I I P P R Y I G D G N F M N P G K L L D Y K R F S S D A L K E L Y I A E R D V L E S I T P G L P L T T N F M V S A G G S M L D Y D D W G A E V D F V S N D H Y F T P G E A H F D E V A Y A A S L M D G I S R K E P W F Q M E H S T S A V N W R P I N Y R A E P G S V V R D S L A Q V A M G A D A I C Y F Q W R Q S K A G A E K W H S S M V P H A G E D S Q I F R D V C E L G A D L G R L S D E G L M G T K T V K S K V A V V F D Y E S Q W A T E Y T A N P T Q Q V D H W T E P L D W F R A L A D N G I T A D V V P V R S D W D S Y E I A V L P C V Y L L S E E T S R R V R E F V A N G G K L F V T Y Y T G L S D E N D H I W L G G Y P G S I R D V V G V R V E E F A P M G N D M P G A L D H L D L D N G T V A H D F A D V I T S T A D T S T V L A S Y K A E R W T G M N E V P A I V A N G Y G D G R T V Y V G C R L G R Q G L A K S L P A M L G S M G L S D L A G D G R V L R V E R A D A A A A S H F E F V F N R T H E P V T V D V E G E A I A A S L A H V D D G R A T I D P T G V V V L R R R R K H S W P Q P L K G A E S R L W Y G G D Y N P D Q W P E E V W D D D I R L M K K A G V N L V S V G I F S W A K I E P E E G K Y D F D W L D R A I D K L G K A G I A V D L A S A T A S P P M W L T Q A H P E V L W K D E R G D T V W P G A R E H W R P T S P V F R E Y A L N L C R R M A E H Y K G N P Y V V A W H V S N E Y G C H N R F D Y S D D A M R A F Q K W C K K R Y K T I D A V N E A W G T A F W A Q H M N D F S E I I P P R Y I G D G N F M N P G K L L D Y K R F S S D A L K E L Y I A E R D V L E S I T P G L P L T T N F M V S A G G S M L D Y D D W G A E V D F V S N D H Y F T P G E A H F D E V A Y A A S L M D G I S R K E P W F Q M E H S T S A V N W R P I N Y R A E P G S V V R D S L A Q V A M G A D A I C Y F Q W R Q S K A G A E K W H S S M V P H A G E D S Q I F R D V C E L G A D L G R L S D E G L M G T K T V K S K V A V V F D Y E S Q W A T E Y T A N P T Q Q V D H W T E P L D W F R A L A D N G I T A D V V P V R S D W D S Y E I A V L P C V Y L L S E E T S R R V R E F V A N G G K L F V T Y Y T G L S D E N D H I W L G G Y P G S I R D V V G V R V E E F A P M G N D M P G A L D H L D L D N G T V A H D F A D V I T S T A D T S T V L A S Y K A E R W T G M N E V P A I V A N G Y G D G R T V Y V G C R L G R Q G L A K S L P A M L G S M G L S G D G R V L R V E R A D S H F E F V F N R T H E P V T V D V E G E A I A A S L A H V D D G R A T I D P T G V V V L R R K R R K H S W P Q P L K G A E S R L W Y G G D Y N P D Q W P E E V W D D D I R L M K K A G V N L V S V G I F S W A K I E P E E G K Y D F D W L D R A I D K L G K A G I A V D L A S A T A S P P M W L T Q A H P E V L W K D E R G D T V W P G A R E H W R P T S P V F R E Y A L N L C R R M A E H Y K G N P Y V V A W H V S N E Y G C H N R F D Y S D D A M R A F Q K W C K K R Y K T I D A V N E A W G T A F W A Q H M N D F S E I I P P R Y I G D G N F M N P G K L L D Y K R F S S D A L K E L Y I A E R D V L E S I T P G L P L T T N F M V S A G G S M L D Y D D W G A E V D F V S N D H Y F T P G E A H F D E V A Y A A S L M D G I S R K E P W F Q M E H S T S A V N W R P I N Y R A E P G S V V R D S L A Q V A M G A D A I C Y F Q W R Q S K A G A E K W H S S M V P H A G E D S Q I F R D V C E L G A D L G R L S D E G L M G T K T V K S K V A V V F D Y E S Q W A T E Y T A N P T Q Q V D H W T E P L D W F R A L A D N G I T A D V V P V R S D W D S Y E I A V L P C V Y L L S E E T S R R V R E F V A N G G K L F V T Y Y T G L S D E N D H I W L G G Y P G S I R D V V G V R V E E F A P M G N D M P G A L D H L D L D N G T V A H D F A D V I T S T A D T S T V L A S Y K A E R W T G M N E V P A I V A N G Y G D G R T V Y V G C R L G R Q G L A K S L P A M L G S M G L S D L A G D G R V L R V E R A D S H F E F V F N R T H E P V T V D V E G E A I A A S L A H V D D G R A T I D P T G V V V L R R

AH

BS

2PY1

GSMSFSGKYQLQSQENFEAFMKAIGLPEELIQKGKDIKGVSEIVQNGKHFKFTITAGSKVIQNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKSVTELNGDIITNTMTLGDIVFKRISKRI

~~~~~~~~~EEEEESSHHHHHHHHT~~HHHHHHHTTS~~~~~B~~BTTBEEE~~~SSS~~~~EEE~TTS~EEEE~TTS~EEEEEEEE~SSSEEEEE~SS~EEEEEEETTEEEEEEEETTEEEEEEEE~~

G S M S F S G K Y Q L Q S Q E N F E A F M K A I G L P E E L I Q K G K D I K G V S E I V Q N G K H F K F T I T A G S K V I Q N E F T V G E E C E L E T M T G E K V K T V V Q L E G D N K L V T T F K N I K S V T E L N G D I I T N T M T L G D I V F K R I S K R I

BS

UNSTRUCTURED

4JP5

KSDVFHLGLTKNDLQGATLAIVPGDPQRVEKIAKLMDNPVHLASHREFTSWRAELDGKAVIVCSTGIGGPSTSIAVEELAQLGVRTFLRIGTTGAIQPHINVGDVLVTTAAVRLDGASLHFAPMEFPAVADFSCTTALVNAAKSVGATTHIGITASSDTFYPGQERYDTFSGRVVRHFKGSMEEWQSMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQESHAVKIVVEAARHLLSDVFHLGLTKNDLQGATLAIVPGDPQRVEKIAKLMDNPVHLASHREFTSWRAELDGKAVIVCSTGIGGPSTSIAVEELAQLGVRTFLRIGTTGAIQPHINVGDVLVTTAAVRLDGASLHFAPMEFPAVADFSCTTALVNAAKSVGATTHIGITASSDTFYPGQERYDTFSGRVVRHFKGSMEEWQSMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQATESHAVKIVVEAARHLLKSDVFHLGLTKNDLQGATLAIVPGDPQRVEKIAKLMDNPVHLASHREFTSWRAELDGKAVIVCSTGIGGPSTSIAVEELAQLGVRTFLRIGTTGAIQPHINVGDVLVTTAAVRLDGASLHFAPMEFPAVADFSCTTALVNAAKSVGATTHIGITASSDTFYPGQERYDTFSGRVVRHFKGSMEEWQSMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQSHAVKIVVEAARHLLSDVFHLGLTKNDLQGATLAIVPGDPQRVEKIAKLMDNPVHLASHREFTSWRAELDGKAVIVCSTGIGGPSTSIAVEELAQLGVRTFLRIGTTGAIQPHINVGDVLVTTAAVRLDGASLHFAPMEFPAVADFSCTTALVNAAKSVGATTHIGITASSDTFYPGQERYDTFSGRVVRHFKGSMEEWQSMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQESHAVKIVVEAARHLLKSDVFHLGLTKNDLQGATLAIVPGDPQRVEKIAKLMDNPVHLASHREFTSWRAELDGKAVIVCSTGIGGPSTSIAVEELAQLGVRTFLRIGTTGAIQPHINVGDVLVTTAAVRLDGASLHFAPMEFPAVADFSCTTALVNAAKSVGATTHIGITASSDTFYPGQERYDTFSGRVVRHFKGSMEEWQSMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQEITESHAVKIVVEAARHLLSDVFHLGLTKNDLQGATLAIVPGDPQRVEKIAKLMDNPVHLASHREFTSWRAELDGKAVIVCSTGIGGPSTSIAVEELAQLGVRTFLRIGTTGAIQPHINVGDVLVTTAAVRLDGASLHFAPMEFPAVADFSCTTALVNAAKSVGATTHIGITASSDTFYPGQERYDTFSGRVVRHFKGSMEEWQSMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQTESHAVKIVVEAARHLL

~~SSSSS~~~GGGGTS~~EEEE~S~THHHHHHHTTSEEEEEEEEETTEEEEEEEETTEEEEEE~~~SSHHHHHHHHHHHHTTT~~EEEEEEEEEE~STT~~TT~EEEEEEEEEESSGGGGTS~TTS~~B~~HHHHHHHHHHHHHHT~~EEEEEEEEES~SSGGGT~~~SSS~~~~GGGTTHHHHHHHTT~~EEESSHHHHHHHHHTTT~EEEEEEEEEEESTT~~~HHHHHHHHHHHHH~~~SSSS~~~HHHHTS~~EEEE~S~THHHHHHHTTSEEEEEEEEETTEEEEEEEETTEEEEEE~~~SSHHHHHHHHHHHHTTT~~EEEEEEEEEE~STT~~TT~EEEEEEEEEESSSGGGTS~TTS~EE~~HHHHHHHHHHHHHTT~~EEEEEEEEES~SSTTTT~~SSSS~~~~GGGTTHHHHHHHTTEEEEESSHHHHHHHHHTTT~EEEEEEEEEEESS~~~~~~HHHHHHHHHHHHT~~~SSSSS~~~GGGGTT~~EEEE~S~TTSHHHHHTTSEEEEEEEEETTEEEEEEEETTEEEEEE~~~SSHHHHHHHHHHHHHTT~~EEEEEEEE~~S~TT~~TT~EEEEEEEEEESSGGGGTS~TTS~~B~~HHHHHHHHHHHHHTT~~EEEEEEEEES~SSGGGT~~~SSS~~~~GGGTTHHHHHHHTT~~~EESSHHHHHHHHHTTT~EEEEEEEE~~~TT~~~HHHHHHHHHHHHT~~~STTT~~~HHHHTS~~EEEE~S~HHHHHHHHTTSEEEEEEEEETTEEEEEEEETTEEEEEE~~~SSHHHHHHHHHHHHHTT~~EEEEEEEEEE~STT~~TT~EEEEEEEEEE~SGGGGTS~TTS~EE~~HHHHHHHHHHHHHHT~~EEEEEEEEES~SSGGGT~~SSSS~~~~TTTTTHHHHHHHTTEEEEESSHHHHHHHHHTTT~EEEEEEEEEEESS~~~~HHHHHHHHHHHTT~~~SSSSS~~~HHHHTT~~EEEE~S~GGGHHHHHTTSEEEEEEEEETTEEEEEEEETTEEEEEE~~~SSHHHHHHHHHHHHHTT~~EEEEEEEE~~~STT~~TT~EEEEEEEEEE~SGGGGTS~TTS~EE~~HHHHHHHHHHHHHHT~~EEEEEEEEES~SSGGGT~~~SSS~~~~TTTTTHHHHHHHTTEEEEESSHHHHHHHHHTTT~EEEEEEEE~~~SS~~~~~~~HHHHHHHHHHHTT~~~SSSS~~~GGGTTS~~EEE~~S~TTTHHHHHTTSEEEEEEEEETTEEEEEEEETTEEEEEE~~~SSHHHHHHHHHHHHHTT~~EEEEEEEEEE~STT~~TT~EEEEEEEEEESSGGGGTS~TTS~EE~~HHHHHHHHHHHHHHT~~EEEEEEEEES~SSGGGT~~SSSS~~~~GGGTTHHHHHHHTT~~EEESSHHHHHHHHHTTT~EEEEEEEEEEETT~~~~TTHHHHHHHHHHH~

K S D V F H L G L T K N D L Q G A T L A I V P G D P Q R V E K I A K L M D N P V H L A S H R E F T S W R A E L D G K A V I V C S T G I G G P S T S I A V E E L A Q L G V R T F L R I G T T G A I Q P H I N V G D V L V T T A A V R L D G A S L H F A P M E F P A V A D F S C T T A L V N A A K S V G A T T H I G I T A S S D T F Y P G Q E R Y D T F S G R V V R H F K G S M E E W Q S M G V M N Y E M E S A T L L T M C A S Q G L R A G M V A G V I V N R T Q Q E S H A V K I V V E A A R H L L S D V F H L G L T K N D L Q G A T L A I V P G D P Q R V E K I A K L M D N P V H L A S H R E F T S W R A E L D G K A V I V C S T G I G G P S T S I A V E E L A Q L G V R T F L R I G T T G A I Q P H I N V G D V L V T T A A V R L D G A S L H F A P M E F P A V A D F S C T T A L V N A A K S V G A T T H I G I T A S S D T F Y P G Q E R Y D T F S G R V V R H F K G S M E E W Q S M G V M N Y E M E S A T L L T M C A S Q G L R A G M V A G V I V N R T Q Q A T E S H A V K I V V E A A R H L L K S D V F H L G L T K N D L Q G A T L A I V P G D P Q R V E K I A K L M D N P V H L A S H R E F T S W R A E L D G K A V I V C S T G I G G P S T S I A V E E L A Q L G V R T F L R I G T T G A I Q P H I N V G D V L V T T A A V R L D G A S L H F A P M E F P A V A D F S C T T A L V N A A K S V G A T T H I G I T A S S D T F Y P G Q E R Y D T F S G R V V R H F K G S M E E W Q S M G V M N Y E M E S A T L L T M C A S Q G L R A G M V A G V I V N R T Q Q S H A V K I V V E A A R H L L S D V F H L G L T K N D L Q G A T L A I V P G D P Q R V E K I A K L M D N P V H L A S H R E F T S W R A E L D G K A V I V C S T G I G G P S T S I A V E E L A Q L G V R T F L R I G T T G A I Q P H I N V G D V L V T T A A V R L D G A S L H F A P M E F P A V A D F S C T T A L V N A A K S V G A T T H I G I T A S S D T F Y P G Q E R Y D T F S G R V V R H F K G S M E E W Q S M G V M N Y E M E S A T L L T M C A S Q G L R A G M V A G V I V N R T Q Q E S H A V K I V V E A A R H L L K S D V F H L G L T K N D L Q G A T L A I V P G D P Q R V E K I A K L M D N P V H L A S H R E F T S W R A E L D G K A V I V C S T G I G G P S T S I A V E E L A Q L G V R T F L R I G T T G A I Q P H I N V G D V L V T T A A V R L D G A S L H F A P M E F P A V A D F S C T T A L V N A A K S V G A T T H I G I T A S S D T F Y P G Q E R Y D T F S G R V V R H F K G S M E E W Q S M G V M N Y E M E S A T L L T M C A S Q G L R A G M V A G V I V N R T Q Q E I T E S H A V K I V V E A A R H L L S D V F H L G L T K N D L Q G A T L A I V P G D P Q R V E K I A K L M D N P V H L A S H R E F T S W R A E L D G K A V I V C S T G I G G P S T S I A V E E L A Q L G V R T F L R I G T T G A I Q P H I N V G D V L V T T A A V R L D G A S L H F A P M E F P A V A D F S C T T A L V N A A K S V G A T T H I G I T A S S D T F Y P G Q E R Y D T F S G R V V R H F K G S M E E W Q S M G V M N Y E M E S A T L L T M C A S Q G L R A G M V A G V I V N R T Q T E S H A V K I V V E A A R H L L

BS

AH

1WEX

GSSGSSGSHHKVSVSPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTFAADVPVYIAGQQAFFNYSTSKRITRPGNSGPSSG

~~SS~~~S~~~~~~~SEEEEES~~SS~~HHHHHHHHTTTS~EEEEEEETTTTEEEEEESSHHHHHHHHHHHHHS~~BSSSSB~EEEE~SSSS~~~S~~S~~~~~

G S S G S S G S H H K V S V S P V V H V R G L C E S V V E A D L V E A L E K F G T I C Y V M M M P F K R Q A L V E F E N I D S A K E C V T F A A D V P V Y I A G Q Q A F F N Y S T S K R I T R P G N S G P S S G

UNSTRUCTURED

BS

4EOI

SMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKDFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPENLLINTEGAIKLADFGLARAFGVPVRTYHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRLVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNLSMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKDFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPENLLINTEGAIKLADFGLARAFGVPVRTYHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL

~GGGEEEEEEEEE~SSSEEEEEEETTT~~EEEEEEEE~~~S~HHHHHHHHHHHH~~~TTB~~EEEEEE~SSEEEEEEE~~SEEHHHHHHHS~TT~S~HHHHHHHHHHHHHHHHHHHHTTEE~~~~SGGGEEE~TTS~EEE~~GGG~EE~~SS~~~~~~~S~GGG~~HHHHTT~S~~~THHHHHHHHHHHHHHHHSS~S~~~SSHHHHHHHHHHHH~~~~TTTSTTGGGSTT~~TT~~~~~~~~HHHHSTT~~HHHHHHHHHHT~SSTTTS~~HHHHTTSGGGTT~~~~~~~~~~~~SSHHHHHHHHHHHHHHT~~~TTHHHH~SS~~HHHHHHHHHHHHHHHHHTT~~HHHHHHHHHHHHHHHTT~~~~GGGHHHHHHHHHHHHHHHH~SS~~~HHHHHHTTTTSS~HHHHHHHHHHHHHHTTT~~~~~~HHHHHHHHHTT~SS~~HHHHHHHHHHHHHHHH~HHHHTTS~HHHHHHHHHHHHHHHHTS~~S~HHHHHHH~~~HHHHHHHHHHHHHHHHHGGGSS~~HHHHHTTSGGGTTGGGS~~~S~~~~~~TTEEEEEEEEE~SSSEEEEEEETTT~~EEEEEEEE~BTTTTBS~HHHHHHHHHHHH~~~TTB~~EEEEE~~SSEEEEEEE~~SEEHHHHHHHTTTT~~~HHHHHHHHHHHHHHHHHHHHTTEE~~~~~GGGEEE~SSS~EEE~~GGG~EE~~SS~~~~~~~S~GGG~~HHHHTT~S~~~THHHHHHHHHHHHHHHHSS~S~~~SSHHHHHHHHHHHH~~~~TTTSTT~TT~TT~~TTS~~~~~~~GGGTSTT~~HHHHHHHHHHT~SSTTTS~~HHHHTTSGGGTT~~~~~~~~~HHHHHHHHHHHHHHT~~~TT~GGG~SS~~HHHHHHHHHHHHHHHHHTT~~HHHHHHHHHHHHHHHHH~~~~GGGHHHHHHHHHHHHHHHH~SS~~~HHHHHHTTTTSS~HHHHHHHHHHHHHHTTT~~~~~~HHHHHHHHHTTSSS~~HHHHHHHHHHHHHHHH~HHHHTTS~HHHHHHHHHHHHHHHHT~~~S~HHHHHHH~~~TTTSHHHHHHHHHHHHHGGGSS~~HHHHHTTSGGGTTTTSS~~~S~~~~

S M E N F Q K V E K I G E G T Y G V V Y K A R N K L T G E V V A L K K I R L E G V P S T A I R E I S L L K E L N H P N I V K L L D V I H T E N K L Y L V F E F L H Q D L K D F M D A S A L T G I P L P L I K S Y L F Q L L Q G L A F C H S H R V L H R D L K P E N L L I N T E G A I K L A D F G L A R A F G V P V R T Y H E V V T L W Y R A P E I L L G C K Y Y S T A V D I W S L G C I F A E M V T R R A L F P G D S E I D Q L F R I F R T L G T P D E V V W P G V T S M P D Y K P S F P K W A R Q D F S K V V P P L D E D G R S L L S Q M L H Y D P N K R I S A K A A L A H P F F Q D V T K P V P H L R L V P D Y H E D I H T Y L R E M E V K C K P K V G Y M K K Q P D I T N S M R A I L V D W L V E V G E E Y K L Q N E T L H L A V N Y I D R F L S S M S V L R G K L Q L V G T A A M L L A S K F E E I Y P P E V A E F V Y I T D D T Y T K K Q V L R M E H L V L K V L T F D L A A P T V N Q F L T Q Y F L H Q Q P A N C K V E S L A M F L G E L S L I D A D P Y L K Y L P S V I A G A A F H L A L Y T V T G Q S W P E S L I R K T G Y T L E S L K P C L M D L H Q T Y L K A P Q H A Q Q S I R E K Y K N S K Y H G V S L L N P P E T L N L S M E N F Q K V E K I G E G T Y G V V Y K A R N K L T G E V V A L K K I R L D T E T E G V P S T A I R E I S L L K E L N H P N I V K L L D V I H T E N K L Y L V F E F L H Q D L K D F M D A S A L T G I P L P L I K S Y L F Q L L Q G L A F C H S H R V L H R D L K P E N L L I N T E G A I K L A D F G L A R A F G V P V R T Y H E V V T L W Y R A P E I L L G C K Y Y S T A V D I W S L G C I F A E M V T R R A L F P G D S E I D Q L F R I F R T L G T P D E V V W P G V T S M P D Y K P S F P K W A R Q D F S K V V P P L D E D G R S L L S Q M L H Y D P N K R I S A K A A L A H P F F Q D V T K P V P H L Y H E D I H T Y L R E M E V K C K P K V G Y M K K Q P D I T N S M R A I L V D W L V E V G E E Y K L Q N E T L H L A V N Y I D R F L S S M S V L R G K L Q L V G T A A M L L A S K F E E I Y P P E V A E F V Y I T D D T Y T K K Q V L R M E H L V L K V L T F D L A A P T V N Q F L T Q Y F L H Q Q P A N C K V E S L A M F L G E L S L I D A D P Y L K Y L P S V I A G A A F H L A L Y T V T G Q S W P E S L I R K T G Y T L E S L K P C L M D L H Q T Y L K A P Q H A Q Q S I R E K Y K N S K Y H G V S L L N P P E T L N L

AH

UNSTRUCTURED

4BRB

GFTRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFGAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFGAGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFGGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHF

~~HHHHHHHHHHHHHHHHHHHH~HHHHHHHHHHHHHHHHHHHS~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT~~S~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~~~GGGSHHHHHHHHHHHHHHHHHHHS~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~SS~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHGGG~EESHHHHHHHHHHHHHHHHS~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~SS~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~~~~HHHHHHHHHHH~HHHHHHHHHHHHHHHHHHHS~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~SS~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~~HHHHHHHHHHHHS~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHT~TTGGGS~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHH~~HHHHHHHHHHHHHHHHHHS~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH~~~~TTHHHHHHHHHHHHHHHHHHHHHHHHHHH~

G F T R I I K A A G Y S W K G L R A A W I N E A A F R Q E G V A V L L C V V I A A W L D V D A V T R V L L I S S V M L V M I V E L L N S A I E A V V D R I G S E Y H E L S G R A K D L G S A A V L I A I I D A V I T W A I L L W S H F A A W I N E A A F R Q E G V A V L L C V V I A A W L D V D A V T R V L L I S S V M L V M I V E L L N S A I E A V V D R I G S E Y H E L S G R A K D L G S A A V L I A I I D A V I T W A I L L W S H F G A A F R Q E G V A V L L C V V I A A W L D V D A V T R V L L I S S V M L V M I V E L L N S A I E A V V D R I G S E Y H E L S G R A K D L G S A A V L I A I I D A V I T W A I L L W S H F G A G Y S W K G L R A A W I N E A A F R Q E G V A V L L C V V I A A W L D V D A V T R V L L I S S V M L V M I V E L L N S A I E A V V D R I G S E Y H E L S G R A K D L G S A A V L I A I I D A V I T W A I L L W S H F G G V A V L L C V V I A A W L D V D A V T R V L L I S S V M L V M I V E L L N S A I E A V V D R I G S E Y H E L S G R A K D L G S A A V L I A I I D A V I T W A I L L W S H F A A F R Q E G V A V L L C V V I A A W L D V D A V T R V L L I S S V M L V M I V E L L N S A I E A V V D R I G S E Y H E L S G R A K D L G S A A V L I A I I D A V I T W A I L L W S H F

AH

UNSTRUCTURED

5D9Z

LGTNYLLSGQTLDREGHLKNGDFDLVMQDDCNLVLYNGNWQSNTANKGRDCKLTLTDYGELVIKNGDGSTVWRSRAQSVKGNYAAVVHPDGRLVVFGPSVFKIDPWVPGNIPFTNNLLFSGQVLYGDGRLTAKSHQLVMQGDCNLVLYGGKYGWQSNTHGNGEHCFLRLNHKGELIIKDDDFKTIWSSSSSSKHGDYVLILRDDGFAVIYGPAIWETSPQA

~~SSEEETT~EE~TT~EEEETTEEEEE~TTS~EEEETTTEE~~~TTS~SS~EEEE~TTS~EEEE~SSS~EEEE~~~~~~SS~~EEEEHHHS~EEEE~SEEEEE~SSS~~~~~~~TTEEETT~EEETTEEEEETTEEEEE~TTS~EEEESSSS~EE~~~TTS~SS~EEEE~SSS~EEEE~TT~~EEEE~~~~~SSS~~EEEE~TTS~EEEE~~EEEESS~~~

L G T N Y L L S G Q T L D R E G H L K N G D F D L V M Q D D C N L V L Y N G N W Q S N T A N K G R D C K L T L T D Y G E L V I K N G D G S T V W R S R A Q S V K G N Y A A V V H P D G R L V V F G P S V F K I D P W V P G N I P F T N N L L F S G Q V L Y G D G R L T A K S H Q L V M Q G D C N L V L Y G G K Y G W Q S N T H G N G E H C F L R L N H K G E L I I K D D D F K T I W S S S S S S K H G D Y V L I L R D D G F A V I Y G P A I W E T S P Q A

BS

UNSTRUCTURED

3PUB

VPNDILEEQLYNSIVVADYDSAVEKSKHLYEEKKSEVITNVVNKLIRNNKMNCMEYAYQLWLQGSKDIVRDCFPVEFRLIFAENAIKLMYKRDGLALTLSNDVHGNDGRLAFGDGKDKTSPKVSWKFIALWENNKVYFKILNTERNQYLVLGVGTNPNGDHMAFGVNSVDSFRAQWYLQPAKYDKDNLFYIYNREYSKALTLSRTLETSGNRMAWGYNGRVIGSPEHYAWGVKAFVPNDILEEQLYNSIVVADYDSAVEKSKHLYEEKKSEVITNVVNKLIRNNKMNCMEYAYQLWLQGSKDIVRDCFPVEFRLIFAENAIKLMYKRDGLALTLSNDVHGNDGRLAFGDGKDKTSPKVSWKFIALWENNKVYFKILNTERNQYLVLGVGTNPNGDHMAFGVNSVDSFRAQWYLQPAKYDKDNLFYIYNREYSKALTLSRTLETSGNRMAWGYNGRVIGSPEHYAWGVKAFA

~~HHHHHHHHHHHHHTT~HHHHHHHHHHHHHTT~HHHHHHHHHHHHHTT~THHHHHHHHHHHTT~HHHHHHHS~HHHHHHHTT~~EEEEETTTTEEEEEEEEE~TTS~EEEEE~SS~SSSGGG~EEEEEEEETTEEEEEEEETTTTEEEEEEEEE~TTS~EEEEEES~~~SGGG~EEEEEEEETTEEEEEEEETTT~~EEEE~SS~~TTS~EEEEEE~S~~TT~HHHH~EEEEE~~~HHHHHHHHHHHHHTT~HHHHHHHHHHHHHTT~HHHHHHHHHHHHHTT~THHHHHHHHHHHTT~HHHHHHHS~HHHHHHHTT~~EEEEETTTTEEEEEEEEE~GGG~EEEEEESS~SSSGGG~EEEEEEEETTEEEEEEEETTTTEEEEEEEEE~TTS~EEEEEES~~~SGGG~EEEEEEEETTEEEEEEEETTT~~EEEE~SS~~TTS~EEEEEE~S~~TT~HHHH~EEEEE~~

V P N D I L E E Q L Y N S I V V A D Y D S A V E K S K H L Y E E K K S E V I T N V V N K L I R N N K M N C M E Y A Y Q L W L Q G S K D I V R D C F P V E F R L I F A E N A I K L M Y K R D G L A L T L S N D V H G N D G R L A F G D G K D K T S P K V S W K F I A L W E N N K V Y F K I L N T E R N Q Y L V L G V G T N P N G D H M A F G V N S V D S F R A Q W Y L Q P A K Y D K D N L F Y I Y N R E Y S K A L T L S R T L E T S G N R M A W G Y N G R V I G S P E H Y A W G V K A F V P N D I L E E Q L Y N S I V V A D Y D S A V E K S K H L Y E E K K S E V I T N V V N K L I R N N K M N C M E Y A Y Q L W L Q G S K D I V R D C F P V E F R L I F A E N A I K L M Y K R D G L A L T L S N D V H G N D G R L A F G D G K D K T S P K V S W K F I A L W E N N K V Y F K I L N T E R N Q Y L V L G V G T N P N G D H M A F G V N S V D S F R A Q W Y L Q P A K Y D K D N L F Y I Y N R E Y S K A L T L S R T L E T S G N R M A W G Y N G R V I G S P E H Y A W G V K A F A

BS

AH

4ZN7

SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRKILHRLLQDKHKILHRLLQD

~~GGGS~HHHHHHHHHHH~~~~~~~~~~~~SS~~HHHHHHHHHHHHHHHHHHHHHHHHTSTTSTTS~HHHHHHHHHHHHHHHHHHHHHHHTTTSTTEEEEETTEEEEGGGGGGSTTHHHHHHHHHHHHHHHHHHT~~HHHHHHHHHHHHHHTTGGG~~HHHHHHHHHHHHHHHHHHHHTT~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS~~~HHHHHHHHTT~~~TTT~~HHHHHHHHHHT~~~~~~~~~~TTS~~~HHHHHHHHHHHHHHHHHHHHHHHTTSTTGGGS~HHHHHHHHHHHHHHHHHHHHHHHHTTSTT~EEEETTEEE~TTGGGGSTTHHHHHHHHHHHHHHHHHHT~~HHHHHHHHHHHHHHTTTT~~~HHHHHHHHHHHHHHHHHHHHHHTT~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS~~~HHHHHHHHTT~~HHHHHHH~~~~HHHHHHH~

S L A L S L T A D Q M V S A L L D A E P P I L Y S E Y D P T R P F S E A S M M G L L T N L A D R E L V H M I N W A K R V P G F V D L T L H D Q V H L L E C A W L E I L M I G L V W R S M E H P G K L L F A P N L L L D R N Q G K C V E G M V E I F D M L L A T S S R F R M M N L Q G E E F V C L K S I I L L N S G V Y T F K D H I H R V L D K I T D T L I H L M A K A G L T L Q Q Q H Q R L A Q L L L I L S H I R H M S N K G M E H L Y S M K C K N V V P L S D L L L E M L D A H R S L A L S L T A D Q M V S A L L D A E P P I L Y S E Y D P T R P F S E A S M M G L L T N L A D R E L V H M I N W A K R V P G F V D L T L H D Q V H L L E C A W L E I L M I G L V W R S M E H P G K L L F A P N L L L D R N Q G K C V E G M V E I F D M L L A T S S R F R M M N L Q G E E F V C L K S I I L L N S G V Y T F E E K D H I H R V L D K I T D T L I H L M A K A G L T L Q Q Q H Q R L A Q L L L I L S H I R H M S N K G M E H L Y S M K C K N V V P L S D L L L E M L D A H R K I L H R L L Q D K H K I L H R L L Q D

AH

UNSTRUCTURED

2QCE

MELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELITLAKHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLPLHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRLG

~~~~HHHHTT~TT~~HHHHHHHHHHHHHT~~EEEE~~~S~HHHHHHHHHHHGGG~SEEEE~GGG~TT~~HHHHHHHHHHH~~~~EEEEEEEE~S~HHHHHHHHH~TTT~GGGT~SEEEEESTT~THHHHHHHHHHTTTT~EEEEE~~~~STT~~~~HHHHHHHHHHHHHTTTTEEEEE~SS~~~~~TTSEEEE~SB~SSS~B~TTS~B~B~HHHHHHTS~~SEEEESHHHHTSS~HHHHHHHHHHHHHHHHHHHH~

M E L S F G A R A E L P R I H P V A S K L L R L M Q K K E T N L C L S A D V S L A R E L L Q L A D A L G P S I C M L K T H V D I L N D F T L D V M K E L I T L A K H E F L I F E D R K F A D I G N T V K K Q Y E G G I F K I A S W A D L V N A H V V P G S G V V K G L Q E V G L P L H R G C L L I A E M S S T G S L A T G D Y T R A A V R M A E E H S E F V V G F I S G S R V S M K P E F L H L T P G V Q L E A G G D N L G Q Q Y N S P Q E V I G K R G S D I I I V G R G I I S A A D R L E A A E M Y R K A A W E A Y L S R L G

AH

UNSTRUCTURED

3SV9

HMASMKKKGSVVIVGRINLSGDTAYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVSTATQTFLATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRTAVSTRGVAKAVDFIPVESLETTMR

~~TT~~~~~~BEEEEEEE~SSSS~EEEE~S~HHHHHHHHHH~B~~S~~~BSEEEEE~SS~EEEEEEETTEEEEEHHHHTT~~B~BTTS~B~~SEEETTTTEEEEE~~TTB~~B~B~~S~~~EEEEE~TT~~EEEEEE~SSSEEEEEEEEEGGGGTT~TT~EEE~TTS~EEEEEEEEEEETTEEEEEEEEEHHHHHHHH~

H M A S M K K K G S V V I V G R I N L S G D T A Y A Q Q T R G E E G C Q E T S Q T G R D K N Q V E G E V Q I V S T A T Q T F L A T S I N G V L W T V Y H G A G T R T I A S P K G P V T Q M Y T N V D K D L V G W Q A P Q G S R S L T P C T C G S S D L Y L V T R H A D V I P V R R R G D S R G S L L S P R P I S Y L K G S S G G P L L C P A G H A V G I F R T A V S T R G V A K A V D F I P V E S L E T T M R

BS

UNSTRUCTURED

1HNV

PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIRKPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWY

~~~~~~~~~~~B~TT~~~~~~~~~~~~HHHHHHHHHHHHHHHHTTSEEE~~SS~~~~B~EEEE~~SS~SS~EEEE~~HHHHHHB~~~~~TTS~~~~GGG~B~~SEEEEEE~TTTTTTSB~~TTGGGGSEEE~~~SSS~~~~~EEEESB~~TT~SSHHHHHHHHHHHHHHHHHHHS~SSEEE~~~EEEEEES~~HHHHHHHHHHHHHHHHHTT~~~~~GGG~~~SSEEETTEEE~SS~EEE~~~~~~~~S~~BHHHHHHHHHHHHHHHTTSTT~~~HHHHHHT~S~S~TTSB~~~~HHHHHHHHHHHHHTTS~~~B~~B~TTS~~EEEEEEEETTEEEEEEESSTT~EEEEE~~BTTSSSS~~HHHHHHHHHHHHHHHHHHHHSS~~EEEESB~HHHHTTTTTT~SSB~~~~SEEE~~~SS~B~~~~~~~SS~~SSSEEEE~EEEEETTTTEEEEEEEBSSS~EEEEEEES~~HHHHHHHHHHHHHHS~~SBEEEEBS~SHHHHHHHT~~~S~S~HHHHHHHHHHHH~SB~~~~B~~TTS~~HHHHHHHHGGGGT~~~~~~~~~~~~~~~~SS~~~~B~~~~~~~HHHHHHHHHHHHHHHHTTSEEE~~TT~~~B~~EEEEEHHHH~SEEEEE~~HHHHHHHHHHHHHHS~~~~~GGGGGSSEEEEEE~TTTTSSS~~~TTGGGGG~~EE~~GGG~S~~EEEEESS~~SS~SHHHHHTHHHHHHHHHHHHHH~SSSEEEEETTEEEEEE~~~HHHHHHHHHHHHHHHHHHH~~~~~~~~~SS~~SS~~~S~B~TTS~~~~~~~~~~~SS~~HHHHHHHHHHHHHHTTSSTT~~~HHHHSTT~S~~~SSS~~~~~HHHHHHHHHHHHHTTS~~S~~~~~SSS~~EEEEEE~SSS~EEEEEESBTTB~SEEEEE~~~SSS~~~HHHHHHHHHHHHHHHHHHHTSS~~BEEE~B~HHHHHHHHHHH~~~S~~~~EEE~~S~~TT~S~~

P I S P I E T V P V K L K P G M D G P K V K Q W P L T E E K I K A L V E I C T E M E K E G K I S K I G P E N P Y N T P V F A I K K K D S T K W R K L V D F R E L N K R T Q D F W E V Q L G I P H P A G L K K K K S V T V L D V G D A Y F S V P L D E D F R K Y T A F T I P S I N N E T P G I R Y Q Y N V L P Q G W K G S P A I F Q S S M T K I L E P F K K Q N P D I V I Y Q M D D L Y V G S D L E I G Q H R T K I E E L R Q H L L R W G L T T P D K K H Q K E P P F L W M G Y E L H P D K W T V Q P I V L P E K D S W T V N D I Q K L V G K L N W A S Q I Y P G I K V R Q L S K L L R G T K A L T E V I P L T E E A E L E L A E N R E I L K E P V H G V Y Y D P S K D L I A E I Q K Q G Q G Q W T Y Q I Y Q E P F K N L K T G K Y A R M R G A H T N D V K Q L T E A V Q K I T T E S I V I W G K T P K F K L P I Q K E T W E T W W T E Y W Q A T W I P E W E F V N T P P L V K L W Y Q L E K E P I V G A E T F Y V D G A A N R E T K L G K A G Y V T N K G R Q K V V P L T N T T N Q K T E L Q A I Y L A L Q D S G L E V N I V T D S Q Y A L G I I Q A Q P D K S E S E L V N Q I I E Q L I K K E K V Y L A W V P A H K G I G G N E Q V D K L V S A G I R K P I S P I E T V P V K L K P G M D G P K V K Q W P L T E E K I K A L V E I C T E M E K E G K I S K I G P E N P Y N T P V F A I K K K D S T K W R K L V D F R E L N K R T Q D F W E V Q L G I P H P A G L K K K K S V T V L D V G D A Y F S V P L D E D F R K Y T A F T I P S I N N E T P G I R Y Q Y N V L P Q G W K G S P A I F Q S S M T K I L E P F K K Q N P D I V I Y Q Y M D D L Y V G S D L E I G Q H R T K I E E L R Q H L L R W G L T T P D K K H Q K E P P F L W M G Y E L H P D K W T V Q P I V L P E K D S W T V N D I Q K L V G K L N W A S Q I Y P G I K V R Q L S K L L R G T K A L T E V I P L T E E A E L E L A E N R E I L K E P V H G V Y Y D P S K D L I A E I Q K Q G Q G Q W T Y Q I Y Q E P F K N L K T G K Y A R M R G A H T N D V K Q L T E A V Q K I T T E S I V I W G K T P K F K L P I Q K E T W E T W W T E Y W Q A T W I P E W E F V N T P P L V K L W Y

UNSTRUCTURED

AH

4DEM

DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK

~HHHHHHHHHHHTHHHHHHHHHTHHHH~GGGHHHHHHHHHHHHHHSSSS~~HHHHHHHHHHHHHS~GGG~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT~~EETTEE~GGGSTTTGGGHHHHHHHHHHHHHHHHHHHHTTSTTHHHHHHHHHHHHHHHHHHHHHHHHHS~TTS~~GGG~~HHHHHHHHHHHTHHHHTHHHHHHHHHHTT~~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHS~HHHH~S~~~TTTTT~~~HHHHHHHHH~~HHHHHHHHHHTT~~~HHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHHHH~TTS~HHHHHHHHHHHTT~~~

D V Y A Q E K Q D F V Q H F S Q I V R V L T E D E M G H P E I G D A I A R L K E V L E Y N A I G G K Y N R G L T V V V A F R E L V E P R K Q D A D S L Q R A W T V G W C V E L L Q A F F L V A D D I M D S S L T R R G Q I C W Y Q K P G V G L D A I N D A N L L E A C I Y R L L K L Y C R E Q P Y Y L N L I E L F L Q S S Y Q T E I G Q T L D L L T A P Q G N V D L V R F T E K R Y K S I V K Y K T A F Y S F Y L P I A A A M Y M A G I D G E K E H A N A K K I L L E M G E F F Q I Q D D Y L D L F G D P S V T G K I G T D I Q D N K C S W L V V Q C L Q R A T P E Q Y Q I L K E N Y G Q K E A E K V A R V K A L Y E E L D L P A V F L Q Y E E D S Y S H I M A L I E Q Y A A P L P P A V F L G L A R K I Y K R R K

AH

UNSTRUCTURED

3QTL

AQTVPYGIPLIKADKVQAQGFKGANVKVAVLDTGIQASHPDLNVVGGASFVAGEAYNTDGNGHGTHVAGTVAALDNTTGVLGVAPSVSLYAVKVLNSSGSGSYSGIVSGIEWATTNGMDVINMSLGGASGSTAMKQAVDNAYARGVVVVAAAGNSGNTIGYPAKYDSVIAVGAVDSNSNRASFSSVGAELEVMAPGAGVYSTYPTNTYATLNGTSMASPHVAGAAALILSKHPNLSASQVRNRLSSTATYLGSSFYYGKGLINVEAAAQAQTVPYGIPLIKADKVQAQGFKGANVKVAVLDTGIQASHPDLNVVGGASFVAGEAYNTDGNGHGTHVAGTVAALDNTTGVLGVAPSVSLYAVKVLNSSGSGSYSGIVSGIEWATTNGMDVINMSLGGASGSTAMKQAVDNAYARGVVVVAAAGNSGSSGNTNTIGYPAKYDSVIAVGAVDSNSNRASFSSVGAELEVMAPGAGVYSTYPTNTYATLNGTSMASPHVAGAAALILSKHPNLSASQVRNRLSSTATYLGSSFYYGKGLINVEAAAQAQTVPYGIPLIKADKVQAQGFKGANVKVAVLDTGIQASHPDLNVVGGASFVAGEAYNTDGNGHGTHVAGTVAALDNTTGVLGVAPSVSLYAVKVLNSSGSGSYSGIVSGIEWATTNGMDVINMSLGGASGSTAMKQAVDNAYARGVVVVAAAGNSGSSGNTNTIGYPAKYDSVIAVGAVDSNSNRASFSSVGAELEVMAPGAGVYSTYPTNTYATLNGTSMASPHVAGAAALILSKHPNLSASQVRNRLSSTATYLGSSFYYGKGLINVEAAAQAPCPHTYKPVCGANGEVYDNECFLNKAGIEPAESWETCRGHELCPSVCTEEYDPVCVEGKIYGNRCMQSHFCGKV

~~~~~THHHHTTHHHHHHHT~S~TT~EEEEEES~~~TT~TT~~EEEEEE~STT~~SS~~SSSHHHHHHHHHH~~~SSSS~~~SSTT~EEEEEE~S~TTS~~~HHHHHHHHHHHHHTT~SEEEE~EEBSS~~HHHHHHHHHHHHTT~EEEEE~~S~~~~~~BTTTSTTSEEEEEE~TTS~B~TT~~~STT~~EEEE~SSEEEEETTTEEEEE~SHHHHHHHHHHHHHHHHHHSTT~~HHHHHHHHHTT~B~~S~HHHHTT~B~~HHHHT~~~~~~THHHHTTHHHHHHTT~S~TT~EEEEEES~~~TT~TT~~EEEEEE~STT~~TT~~SSSHHHHHHHHHH~~~SSSS~~~SSTTSEEEEEE~S~TTS~~~HHHHHHHHHHHHHTT~SEEEE~~~BS~~~HHHHHHHHHHHHHT~EEEEE~~S~~~~TT~~~~~BTTTSTTSEEEEEE~TTS~B~TT~~~STT~~EEEE~SSEEEEETTTEEEEE~SHHHHHHHHHHHHHHHHHH~TT~~HHHHHHHHHTS~B~~S~HHHHTT~B~~HHHHT~~B~~~THHHHTTHHHHHTTT~S~TT~EEEEEES~~~TT~TT~~EEEEEE~STT~~SS~~SSSHHHHHHHHHH~~~SSSB~~~SSTTSEEEEEE~S~TTS~~~HHHHHHHHHHHHHTT~SEEEE~B~BSS~~HHHHHHHHHHHTTT~EEEEE~~S~~~~TT~~~~~BTTSSTTSEEE~~B~TTS~B~TTS~~SSSEEEB~B~SSEEEEETTTEEEEE~SHHHHHHHHHHHHHHHHHHSTT~~HHHHHHHHHHTSB~~S~TTTSTT~B~~HHHHT~~~EE~~~~~EEBTTS~EESSHHHHHHTT~~B~S~GGGG~SSSSS~S~~B~~~~~~~SSSS~~SSHHHHH~STT~~

A Q T V P Y G I P L I K A D K V Q A Q G F K G A N V K V A V L D T G I Q A S H P D L N V V G G A S F V A G E A Y N T D G N G H G T H V A G T V A A L D N T T G V L G V A P S V S L Y A V K V L N S S G S G S Y S G I V S G I E W A T T N G M D V I N M S L G G A S G S T A M K Q A V D N A Y A R G V V V V A A A G N S G N T I G Y P A K Y D S V I A V G A V D S N S N R A S F S S V G A E L E V M A P G A G V Y S T Y P T N T Y A T L N G T S M A S P H V A G A A A L I L S K H P N L S A S Q V R N R L S S T A T Y L G S S F Y Y G K G L I N V E A A A Q A Q T V P Y G I P L I K A D K V Q A Q G F K G A N V K V A V L D T G I Q A S H P D L N V V G G A S F V A G E A Y N T D G N G H G T H V A G T V A A L D N T T G V L G V A P S V S L Y A V K V L N S S G S G S Y S G I V S G I E W A T T N G M D V I N M S L G G A S G S T A M K Q A V D N A Y A R G V V V V A A A G N S G S S G N T N T I G Y P A K Y D S V I A V G A V D S N S N R A S F S S V G A E L E V M A P G A G V Y S T Y P T N T Y A T L N G T S M A S P H V A G A A A L I L S K H P N L S A S Q V R N R L S S T A T Y L G S S F Y Y G K G L I N V E A A A Q A Q T V P Y G I P L I K A D K V Q A Q G F K G A N V K V A V L D T G I Q A S H P D L N V V G G A S F V A G E A Y N T D G N G H G T H V A G T V A A L D N T T G V L G V A P S V S L Y A V K V L N S S G S G S Y S G I V S G I E W A T T N G M D V I N M S L G G A S G S T A M K Q A V D N A Y A R G V V V V A A A G N S G S S G N T N T I G Y P A K Y D S V I A V G A V D S N S N R A S F S S V G A E L E V M A P G A G V Y S T Y P T N T Y A T L N G T S M A S P H V A G A A A L I L S K H P N L S A S Q V R N R L S S T A T Y L G S S F Y Y G K G L I N V E A A A Q A P C P H T Y K P V C G A N G E V Y D N E C F L N K A G I E P A E S W E T C R G H E L C P S V C T E E Y D P V C V E G K I Y G N R C M Q S H F C G K V

AH

UNSTRUCTURED

3CLS

MKILVAVKQTAALEEDFEIREDGMDVDEDFMMYDLNEWDDFSLEEAMKIKESSDTDVEVVVVSVGPDRVDESLRKCLAKGADRAVRVWDDAAEGSDAIVVGRILTEVIKKEAPDMVFAGVQSSDQAYASTGISVASYLNWPHAAVVADLQYKPGDNKAVIRRELEGGMLQEVEINCPAVLTIQLGINKPRYASTKPIEEVSLADIGLSANDVGAAQSMSRVRRMYIPEKGRATMIEGTISEQAAKIIQIINEFKSKILVIAEHRRNDLRPVSLELIGAANGLKKSGEDKVVVAVIGSQADAFVPALSVNGVDELVVVKGSSIDFDPDVFEASVSALIAAHNPSVVLLPHSVDSLGYASSLASKTGYGFATDVYIVEYQGDELVATRGGYNQKVNVEVDFPGKSTVVLTIRPSVFKPLEGAGSPVVSNVDAPSVQSRSQNKDYVEVGGGNDIDITTVDFIMSIGRGIGEETNVEQFRELADEAGATLCCSCPIADAGWLPKSRQVGQSGKVVGSCKLYVAMGISGSIQHMAGMKHVPTIIAVNTDPGASIFTIAKYGIVADIFDIEEELKAQL

~EEEEE~~EEEEE~TT~~B~TTSSSB~GGGEEEEE~HHHHHHHHHHHHHHHH~SS~~EEEEEEES~TTHHHHHHHHHHTT~SEEEEE~~GGGTT~~HHHHHHHHHHHHHHH~~SEEEEES~~TTT~~~~HHHHHHHHHT~~EEEEEEEEE~~TT~SEEEEEEEETTTEEEEEEEESS~EEEE~TTSS~~TT~~~~~~EEE~TGGGT~~GGGSSGGGSSSEEEEEE~~~~~~~EE~~S~HHHHHHHHHHHHHHH~~EEEEE~~EETTEE~THHHHHHHHHHHH~SSTT~EEEEEEESTTGGGGHHHH~BTT~SEEEEEE~S~SS~~HHHHHHHHHHHHHHH~~SEEEEESSHHHHTTHHHHHHHSS~EEEEEE~EEEEETTEEEEEEEETTTTEEEEEE~TT~S~EEEEE~TTSS~~~~SB~~~EEEEEE~~~~~~SEEEEEEE~~~S~~S~~TTS~SEEEEE~GGG~SGGGHHHHHHHHHHHT~EEEE~HHHHHTTSS~GGGBBSSSSB~~TT~SEEEEES~~~~HHHHHHHTT~SEEEEE~S~TT~GGGGT~SEEE~S~HHHHHHHHHHH~

M K I L V A V K Q T A A L E E D F E I R E D G M D V D E D F M M Y D L N E W D D F S L E E A M K I K E S S D T D V E V V V V S V G P D R V D E S L R K C L A K G A D R A V R V W D D A A E G S D A I V V G R I L T E V I K K E A P D M V F A G V Q S S D Q A Y A S T G I S V A S Y L N W P H A A V V A D L Q Y K P G D N K A V I R R E L E G G M L Q E V E I N C P A V L T I Q L G I N K P R Y A S T K P I E E V S L A D I G L S A N D V G A A Q S M S R V R R M Y I P E K G R A T M I E G T I S E Q A A K I I Q I I N E F K S K I L V I A E H R R N D L R P V S L E L I G A A N G L K K S G E D K V V V A V I G S Q A D A F V P A L S V N G V D E L V V V K G S S I D F D P D V F E A S V S A L I A A H N P S V V L L P H S V D S L G Y A S S L A S K T G Y G F A T D V Y I V E Y Q G D E L V A T R G G Y N Q K V N V E V D F P G K S T V V L T I R P S V F K P L E G A G S P V V S N V D A P S V Q S R S Q N K D Y V E V G G G N D I D I T T V D F I M S I G R G I G E E T N V E Q F R E L A D E A G A T L C C S C P I A D A G W L P K S R Q V G Q S G K V V G S C K L Y V A M G I S G S I Q H M A G M K H V P T I I A V N T D P G A S I F T I A K Y G I V A D I F D I E E E L K A Q L

BS

AH

5F7G

TRDQNGTWEMESNENFEGWMKALDIDFATRKIAVRLTLTLVIDQDGDNFKVKTTSTFYNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKKWIEGDKLYLELTCGDQVCRQVFKKKTRDQNGTWEMESNENFEGWMKALDIDFATRKIAVRLTLTLVIDQDGDNFKVKTTSTFYNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKKWIEGDKLYLELTCGDQVCRQVFKKK

~~~~~EEEEEEEEESHHHHHHHTT~~HHHHHHHTT~~~EEEEEEETTEEEEEEE~SS~EEEEEEETT~~EEEE~TTTT~~EEEEEEEEETTEEEEEEESSSTT~EEEEEEETTEEEEEEEETTEEEEEEEEE~~~~~~EEEEEEEEESHHHHHHHTT~~HHHHHHHTTB~~EEEEEEETTEEEEEEE~SS~EEEEEEETT~~EEEE~HHHH~~EEEEEEEEETTEEEEEEESSSTT~EEEEEEETTEEEEEEEETTEEEEEEEEE~

T R D Q N G T W E M E S N E N F E G W M K A L D I D F A T R K I A V R L T L T L V I D Q D G D N F K V K T T S T F Y N Y D V D F T V G V E F D E Y T K S L D N R H V K A L V T W E G D V L V C V Q K G E K E N R G W K K W I E G D K L Y L E L T C G D Q V C R Q V F K K K T R D Q N G T W E M E S N E N F E G W M K A L D I D F A T R K I A V R L T L T L V I D Q D G D N F K V K T T S T F Y N Y D V D F T V G V E F D E Y T K S L D N R H V K A L V T W E G D V L V C V Q K G E K E N R G W K K W I E G D K L Y L E L T C G D Q V C R Q V F K K K

BS

UNSTRUCTURED

4O8V

PGVVLGRDQWLFSDEEFKPTAGAEQLQENLALIRGVRDTLQQHGSQLVLAIVPAKARVYTEYLGKERPASLHDDLYNQFHAQARQANVFAPDLAPEQAKARGQVFLRTDTHWTPGAEVAAQALAEAVSRQSLLNGDPQAFITEAGNTAPYKGDLTNFLPDPLFSNLLPAPDNLQKRTTRPVDQIPVALVGTSYSANPHWNFLGALQQALRSDVANYAEDGHGPLLPLKYLQSDAFKNAAPQVVVWEFPERYLPKNDLSSFDPQWIAQLKNSRRPGVVLGRDQWLFSDEEFKPTAGAEQLQENLALIRGVRDTLQQHGSQLVLAIVPAKARVYTEYLGKERPASLHDDLYNQFHAQARQANVFAPDLAPEQAKARGQVFLRTDTHWTPGAEVAAQALAEAVSRQSLLNGDPQAFITEAGNTAPYKGDLTNFLPLDFSNLLPAPDNLQKRTTRPVDQIPVALVGTSYSANPHWNFLGALQQALRSDVANYAEDGHGPLLPLKYLQSDAFKNAAPQVVVWEFPERYLPKNDLSSFDPQWIAQLKNSR

~~EEE~STT~EEEGGGT~~~TTTTT~~HHHHHHHHHHHHHHHTT~EEEEEEE~~HHHHTGGG~~S~~~~GGGTTHHHHHHHHHHHTT~~~~~~~~~GGGGTS~SB~SSSSSB~~~HHHHHHHHHHHHHHTT~~~S~~~~EEEEEEEEEEE~~GGGGG~~~GGGGGGS~~~EEEEEEEEEE~~~~SEEEE~SHHHH~GGG~HHHHHHHHHTS~~EE~~~SSSTTT~~~TTTTSHHHHHS~~SEEEEEEEGGG~~~~~~TTS~HHHHHHHHT~~~~~EEE~STT~EEEGGGTS~~TTTTT~~HHHHHHHHHHHHHHHTT~EEEEEEE~~HHHHTGGG~~S~~~~HHHHTHHHHHHHHHHHTT~~~~~~~~~GGGGTS~SB~SSSSSB~~~HHHHHHHHHHHHHHTT~~~S~~~~EEEEEEEEEEE~~GGGGGS~~~~GGGS~~~EEEEEEEEEE~~~~SEEEE~SHHHH~GGG~HHHHHHHHHTS~EEE~~~SSSTTT~~~TGGGSHHHHH~~~SEEEEEEEGGG~~~~~~TTS~HHHHHHHHT~~

P G V V L G R D Q W L F S D E E F K P T A G A E Q L Q E N L A L I R G V R D T L Q Q H G S Q L V L A I V P A K A R V Y T E Y L G K E R P A S L H D D L Y N Q F H A Q A R Q A N V F A P D L A P E Q A K A R G Q V F L R T D T H W T P G A E V A A Q A L A E A V S R Q S L L N G D P Q A F I T E A G N T A P Y K G D L T N F L P D P L F S N L L P A P D N L Q K R T T R P V D Q I P V A L V G T S Y S A N P H W N F L G A L Q Q A L R S D V A N Y A E D G H G P L L P L K Y L Q S D A F K N A A P Q V V V W E F P E R Y L P K N D L S S F D P Q W I A Q L K N S R R P G V V L G R D Q W L F S D E E F K P T A G A E Q L Q E N L A L I R G V R D T L Q Q H G S Q L V L A I V P A K A R V Y T E Y L G K E R P A S L H D D L Y N Q F H A Q A R Q A N V F A P D L A P E Q A K A R G Q V F L R T D T H W T P G A E V A A Q A L A E A V S R Q S L L N G D P Q A F I T E A G N T A P Y K G D L T N F L P L D F S N L L P A P D N L Q K R T T R P V D Q I P V A L V G T S Y S A N P H W N F L G A L Q Q A L R S D V A N Y A E D G H G P L L P L K Y L Q S D A F K N A A P Q V V V W E F P E R Y L P K N D L S S F D P Q W I A Q L K N S R

UNSTRUCTURED

AH

1LCA

MLEQPYLDLAKKVLDEGHFKPDRTHTGTYSIFGHQMRFDLSKGFPLLTTKKVPFGLIKSELLWFLHGDTNIRFLLQHRNHIWDEWAFEKWVKSDEYHGPDMTDFGHRSQKDPEFAAVYHEEMAKFDDRVLHDDAFAAKYGDLGLVYGSQWRAWHTSKGDTIDQLGDVIEQIKTHPYSRRLIVSAWNPEDVPTMALPPCHTLYQFYVNDGKLSLQLYQRSADIFLGVPFNIASYALLTHLVAHECGLEVGEFIHTFGDAHLYVNHLDQIKEQLSRTPRPAPTLQLNPDKHDIFDFDMKDIKLLNYDPYPAIKAPVAV

~TTHHHHHHHHHHHHH~EEEE~SSS~EEEEEEEEEEEEETTS~~~~~SSS~~~HHHHHHHHHHHHTT~~~THHHHHTT~~TTHHHHHHHHHTSSS~~SS~~TTGGGGTSSSSSHHHHHHHHHHHHHHHHTT~HHHHHHHTT~~SSHHHHHH~B~~TTS~~B~HHHHHHHHHHH~TT~TT~EEE~~~TTTTTS~SS~~SS~EEEEEEETTEEEEEEEEEEEETTTHHHHHHHHHHHHHHHHHHHTT~EE~EEEEEEEEEEEEGGGHHHHHHHTT~~~~~~~EEEE~SS~~~GGG~~GGGEEEE~~~~~~~~~~~~~~

M L E Q P Y L D L A K K V L D E G H F K P D R T H T G T Y S I F G H Q M R F D L S K G F P L L T T K K V P F G L I K S E L L W F L H G D T N I R F L L Q H R N H I W D E W A F E K W V K S D E Y H G P D M T D F G H R S Q K D P E F A A V Y H E E M A K F D D R V L H D D A F A A K Y G D L G L V Y G S Q W R A W H T S K G D T I D Q L G D V I E Q I K T H P Y S R R L I V S A W N P E D V P T M A L P P C H T L Y Q F Y V N D G K L S L Q L Y Q R S A D I F L G V P F N I A S Y A L L T H L V A H E C G L E V G E F I H T F G D A H L Y V N H L D Q I K E Q L S R T P R P A P T L Q L N P D K H D I F D F D M K D I K L L N Y D P Y P A I K A P V A V

AH

UNSTRUCTURED

3BBJ

TRFDSATEVVRVGENRYAVELDPGYLIGTANGGYLTVLQRSALAESDHLHAVSSSYHFHRPASSGPAEIETRVLKRGRTVTTVQTTLFQEGRTILTGTLATATLDPHAEPRYAAPQPAIPPQHQCRRVDPRQSHLPDDGFLARVDVDFSPDSYAALARERTVTTPELCGYVDLSARDGGSAKDPLAFLPLAVDALPPIVSLLVDWSWAPTVELTWHLRAIPEPGPLAFRSTCALVSDGWFDENVDLWDARGRLVAQSRQLARVGRGVPTRFDSATEVVRVGENRYAVELDPGYLIGTANGGYLTVLQRSALAESDHLHAVSSSYHFHRPASSGPAEIETRVLKRGRTVTTVQTTLFQEGRTILTGTLATATLDPHAEPRYAAPQPAIPPQHQCRRVDPDDGFLARVDVDFSPDSYAALARERTVTTPELCGYVDLSARDGGSAKDPLAFLPLAVDALPPIVSLLVDWSWAPTVELTWHLRAIPEPGPLAFRSTCALVSDGWFDENVDLWDARGRLVAQSRQLARVGR

~HHHHHT~EEEEETTEEEEEE~GGG~SS~~~TTT~~HHHHHHHHT~SSSEEEEEEEEE~S~~~SEEEEEEEEEEE~~SS~EEEEEEEEETTEEEEEEEEEEE~~~TT~~~SEE~~~~~~~~GGGSEE~~~~~~SSGGG~GGGTEEEEE~HHHHHHHTT~S~~SS~EEEEEEEE~TTTTSS~SSHHHHHHHHTT~S~~GGGGTSS~S~~~EEEEEEEE~S~~~SS~EEEEEE~SEEETTEEEEEEEEE~TTS~EEEEEEEEEETT~~~~~HHHHHT~~EEEETTEEEEEE~GGG~STT~~TTT~~HHHHHHHHT~SSSEEEEEEEEE~S~~~SEEEEEEEEEEE~~SS~EEEEEEEEETTEEEEEEEEEEE~~~TT~~~SEE~~~~~~~~GGG~EE~~~~~SGGGTEEEEE~HHHHHHHTT~S~~SS~EEEEEEEE~TTTTSS~SSHHHHHHHHTT~S~~GGGGT~~~SB~~EEEEEEEE~S~~~SS~EEEEEE~SEEETTEEEEEEEEE~TTS~EEEEEEEEEE~B~

T R F D S A T E V V R V G E N R Y A V E L D P G Y L I G T A N G G Y L T V L Q R S A L A E S D H L H A V S S S Y H F H R P A S S G P A E I E T R V L K R G R T V T T V Q T T L F Q E G R T I L T G T L A T A T L D P H A E P R Y A A P Q P A I P P Q H Q C R R V D P R Q S H L P D D G F L A R V D V D F S P D S Y A A L A R E R T V T T P E L C G Y V D L S A R D G G S A K D P L A F L P L A V D A L P P I V S L L V D W S W A P T V E L T W H L R A I P E P G P L A F R S T C A L V S D G W F D E N V D L W D A R G R L V A Q S R Q L A R V G R G V P T R F D S A T E V V R V G E N R Y A V E L D P G Y L I G T A N G G Y L T V L Q R S A L A E S D H L H A V S S S Y H F H R P A S S G P A E I E T R V L K R G R T V T T V Q T T L F Q E G R T I L T G T L A T A T L D P H A E P R Y A A P Q P A I P P Q H Q C R R V D P D D G F L A R V D V D F S P D S Y A A L A R E R T V T T P E L C G Y V D L S A R D G G S A K D P L A F L P L A V D A L P P I V S L L V D W S W A P T V E L T W H L R A I P E P G P L A F R S T C A L V S D G W F D E N V D L W D A R G R L V A Q S R Q L A R V G R

BS

UNSTRUCTURED

2V1W

MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTHLEAQNRIKGCHDHLTLSVSRPEGESDLSMPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTHLEAQNRIKGCHDHLTLSVSRPEGESDL

~~EEEEEESSS~~~EEEEEEGGGTEEEEEEEE~TTSHHHHTT~~TT~EEEEETTEE~TT~~HHHHHHHHHT~~SEEEEEEE~~TT~~~~~~~EEEEEESSS~~~EEEEEEGGGTEEEEEEEE~TTSHHHHTT~~TT~EEEEETTEE~TT~~HHHHHHHHTS~SSEEEEEEE~~TT~~~~

M P H S V T L R G P S P W G F R L V G G R D F S A P L T I S R V H A G S K A A L A A L C P G D L I Q A I N G E S T E L M T H L E A Q N R I K G C H D H L T L S V S R P E G E S D L S M P H S V T L R G P S P W G F R L V G G R D F S A P L T I S R V H A G S K A A L A A L C P G D L I Q A I N G E S T E L M T H L E A Q N R I K G C H D H L T L S V S R P E G E S D L

BS

UNSTRUCTURED

1AVK

ASPFRLASAGEISEVQGILRTAGLLGPEKRIAYLGVLDPARGAGSEAEDRRFRVFIHDVSGARPQEVTVSVTNGTVISAVELDTAATGELPVLEEEFEVVEQLLATDERWLKALAARNLDVSKVRVAPLSAGVFEYAEERGRRILRGLAFVQDFPEDSAWAHPVDGLVAYVDVVSKEVTRVIDTGVFPVPAEHGNYTDPELTGPLRTTQKPISITQPEGPSFTVTGGNHIEWEKWSLDVGFDVREGVVLHNIAFRDGDRLRPIINRASIAEMVVPYGDPSPIRSWQNYFDTGEYLVGQYANSLELGCDCLGDITYLSPVISDAFGNPREIRNGICMHEEDWGILAKHSDLWSGINYTRRNRRMVISFFTTIGNYDYGFYWYLYLDGTIEFEAKATGVVFTSAFPEGGSDNISQLAPGLGAPFHQHIFSARLDMAIDGFTNRVEEEDVVRQTMGPGNERGNAFSRKRTVLTRESEAVREADARTGRTWIISNPESKNRLNEPVGYKLHAHNQPTLLADPGSSIARRAAFATKDLWVTRYADDERYPTGDFVNQHSGGAGLPSYIAQDRDIDGQDIVVWHTFGLTHFPRVEDWPIMPVDTVGFKLRPEGFFDRSPVLDVPAN

~~TTS~~~HHHHHHHHHHHHHTT~S~TTEEEEEEEE~~~~S~TTS~S~~~EEEEEEEESSS~~~EEEEEETTTTEEEEEEE~~HHHH~~~~~~HHHHTHHHHHHHT~HHHHHHHHTTT~~GGGEEEEEEE~~~~S~TTSTTS~EEEEEEEE~SSTTS~GGGSEEEEEEEEEETTTTEEEEEEE~~~~~~~~S~~~TT~HHHH~S~~~~~~~~~~~~TT~~S~EEETTTEEEETTEEEEEEEETTTEEEEEEEEEE~SS~EEEEEEEEEEEEEEEEB~~~STTTTT~EE~TTTTS~GGGGB~~~~BTTTB~SS~EEE~~EEE~TTS~EEE~TT~EEEEEEEEEEEEEEE~TTT~~EEEEEEEEEEEEEEEEETTEEEEEEEEEETTS~EEEEEEEEE~~~~EE~~TT~~SSEEEEETTEEEE~EEEEEEEEEEE~TTSS~BEEEEEEEEE~~SSSS~STT~~EEEEEEEE~BGGG~EE~~~GGGT~EEEEEEEEEE~TTS~EEEEEEEE~~~~~~~S~TTSHHHHHTGGGGSSEEEEE~~TT~~~TT~S~~TT~~S~TTHHHHHTT~~B~TTB~EEEEEEEEEEE~~~GGGSSSEEEEEEEEEEEESS~SSS~TTTT~~~~

A S P F R L A S A G E I S E V Q G I L R T A G L L G P E K R I A Y L G V L D P A R G A G S E A E D R R F R V F I H D V S G A R P Q E V T V S V T N G T V I S A V E L D T A A T G E L P V L E E E F E V V E Q L L A T D E R W L K A L A A R N L D V S K V R V A P L S A G V F E Y A E E R G R R I L R G L A F V Q D F P E D S A W A H P V D G L V A Y V D V V S K E V T R V I D T G V F P V P A E H G N Y T D P E L T G P L R T T Q K P I S I T Q P E G P S F T V T G G N H I E W E K W S L D V G F D V R E G V V L H N I A F R D G D R L R P I I N R A S I A E M V V P Y G D P S P I R S W Q N Y F D T G E Y L V G Q Y A N S L E L G C D C L G D I T Y L S P V I S D A F G N P R E I R N G I C M H E E D W G I L A K H S D L W S G I N Y T R R N R R M V I S F F T T I G N Y D Y G F Y W Y L Y L D G T I E F E A K A T G V V F T S A F P E G G S D N I S Q L A P G L G A P F H Q H I F S A R L D M A I D G F T N R V E E E D V V R Q T M G P G N E R G N A F S R K R T V L T R E S E A V R E A D A R T G R T W I I S N P E S K N R L N E P V G Y K L H A H N Q P T L L A D P G S S I A R R A A F A T K D L W V T R Y A D D E R Y P T G D F V N Q H S G G A G L P S Y I A Q D R D I D G Q D I V V W H T F G L T H F P R V E D W P I M P V D T V G F K L R P E G F F D R S P V L D V P A N

BS

UNSTRUCTURED

2KMD

HMECADVPLLPSKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCMSGAALCALGKECFLELAPDFVGDILWEHLEILQKEDVK

~~~SSE~~~~~~~HHHHHHHHHHHHHHHHHHHHH~~~S~STT~~HHHHHHHHHHHHHHTT~~S~~SSTT~S~HHHHHHHHHHHHHHHS~TTHHHHHHHHHHHHHHHT~~

H M E C A D V P L L P S K E M M S Q A L K A T F S G F T K E Q Q R L G I P K D P R Q W T E T H V R D W V M W A V N E F S L K G V D F Q K F C M S G A A L C A L G K E C F L E L A P D F V G D I L W E H L E I L Q K E D V K

AH

UNSTRUCTURED

5H1J

EPRTLPPSPNWYCARCSDAVPGGLFGFAARTSVFLVRVGPGAGESPGTPPFRVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLGCYLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERLWLTLHWPSNQPTQLVSSCFGGELLQWDLTQSWRRKYTLFSASSEGQNHSRIVFNLCPLQTEDDKQLLLSTSMDRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLGGEGDRPSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQDHSRPPQ

~~EEE~B~~~SS~TTSEEEETBTEEEEEETTEEEEEEESGGG~~~TTS~SEEEEEEE~~~SS~EEEEEE~~STT~TTEEEEEETTS~EEEEETTTTEEEEEE~~~~S~EEEEEE~SSSTTEEEEEETTSEEEEEEGGGTEEEEEE~~SS~EEEEEE~SS~TTEEEEEETTS~EEEEEGGGTTEEEEEE~~~~S~EEEEEE~SS~SS~~~~~EEEEEETTSEEEEEETTTTEEEEEEE~~~~~~~S~~~~SSS~~~~~~~EE~~TT~TTEEEEE~GGG~EEEEESTTGGGTEEEETTSSSSS~S~SS~EEEEEEEEBTT~~EEEEEEETTSEEEEEETTTTEEEEEEE~BSS~EEEEEE~SSSTTEEEEEETTS~EEEEETT~SS~TT~EEEE~TTT~S~EEEEEE~SSSTTEEEEEETTS~EEEEETTS~S~~EE~SS~~SS~EEEEEEE~~~TTTTSS~TTTS~S~EEEEEETTS~EEEE~TT~TTS~~EETHHHHHHHHT~~S~~~~EEEEEE~TTSSEEEEEETTS~EEEEETTTTEEEEEE~~~SS~EEEEEE~~S~SSSGGGGGEEEEEESSS~EEEEE~HHHHHH~~SS~EEE~S~SEEE~~~SS~EEEEEE~TTSSSEEEEEETTS~EEEEEGGGTEEEEEE~~~SS~EEEEEE~SS~TTEEEEEETTS~EEEEEGGG~~~~S~~~

E P R T L P P S P N W Y C A R C S D A V P G G L F G F A A R T S V F L V R V G P G A G E S P G T P P F R V I G E L V G H T E R V S G F T F S H H P G Q Y N L C A T S S D D G T V K I W D V E T K T V V T E H A L H Q H T I S T L H W S P R V K D L I V S G D E K G V V F C Y W F N R N D S Q H L F I E P R T I F C L T C S P H H E D L V A I G Y K D G I V V I I D I S K K G E V I H R L R G H D D E I H S I A W C P L P G E D C L G C Y L A T G S K D Q T I R I W S C S R G R G V M I L K L P F L K R R G G G I D P T V K E R L W L T L H W P S N Q P T Q L V S S C F G G E L L Q W D L T Q S W R R K Y T L F S A S S E G Q N H S R I V F N L C P L Q T E D D K Q L L L S T S M D R D V K C W D I A T L E C S W T L P S L G G F A Y S L A F S S V D I G S L A I G V G D G M I R V W N T L S I K N N Y D V K N F W Q G V K S K V T A L C W H P T K E G C L A F G T D D G K V G L Y D T Y S N K P P Q I S S T Y H K K T V Y T L A W G P P V P P M S L G G E G D R P S L A L Y S C G G E G I V L Q H N P W K L S G E A F D I N K L I R D T N S I K Y K L P V H T E I S W K A D G K I M A L G N E D G S I E I F Q I P N L K L I C T I Q Q H H K L V N T I S W H H E H G S Q P E L S Y L M A S G S N N A V I Y V H N L K T V I E S S P E S P V T I T E P Y R T L S G H T A K I T S V A W S P H H D G R L V S A S Y D G T A Q V W D A L R E E P L C N F R G H R G R L L C V A W S P L D P D C I Y S G A D D F C V H K W L T S M Q D H S R P P Q

BS

UNSTRUCTURED

4ZSA

LPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEEYELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALT

~~~~TTTB~~GGGEEEEEEESTTTTSEEEEEEEETSSTTSTT~EEEEEEEE~~SS~~HHHHHHHHHHHHHHHHH~~~TTB~~EEEEE~SSSS~EEEEE~~TT~BHHHHHHTTS~~~~~~~HHHHHHHHHHHHHHHHHHHHTT~~~S~~SGGGEEE~TT~~EEE~S~S~~~~STT~~TT~~~TTS~~GGGGS~HHHHHH~~~~HHHHHHHHHHHHHHHHTTS~~SSTT~~HHHHHHHHHTT~~~~~~SS~~HHHHHHHHHHT~SSGGGS~~HHHHHHHHHHHHHHS~S~~~~~~~~~TTTB~~GGGEEEEEE~GGGTTSSEEEEEEE~SSTTSTT~EEEEEEE~~~TT~~HHHHHHHHHHHHHHHHH~~~TTB~~EEEEE~SSS~~EEEEE~~TT~BHHHHHHTT~~~~~~~~HHHHHHHHHHHHHHHHHHHHTT~~~S~~SGGGEEE~TT~~EEE~S~~~~~TT~~~TTS~~GGGGS~HHHHHS~~~~HHHHHHHHHHHHHHHHTTS~~SSTT~~HHHHHHHHHTT~~~~~~SS~~HHHHHHHHHHT~SSGGGS~~HHHHHHHHHHHHHT~

L P E D P R W E L P R D R L V L G K P L G E G A F G Q V V L A E A I G L D K D K P N R V T K V A V K M L K S D A T E K D L S D L I S E M E M M K M I G K H K N I I N L L G A C T Q D G P L Y V I V E Y A S K G N L R E Y L Q A R R P P E E Q L S S K D L V S C A Y Q V A R G M E Y L A S K K C I H R D L A A R N V L V T E D N V M K I A D F G L A R D I H H I D Y Y K K T T N G R L P V K W M A P E A L F D R I Y T H Q S D V W S F G V L L W E I F T L G G S P Y P G V P V E E L F K L L K E G H R M D K P S N C T N E L Y M M M R D C W H A V P S Q R P T F K Q L V E D L D R I V A L T S N Q E E Y E L P E D P R W E L P R D R L V L G K P L G E G A F G Q V V L A E A I G L D K D K P N R V T K V A V K M L K S D A T E K D L S D L I S E M E M M K M I G K H K N I I N L L G A C T Q D G P L Y V I V E Y A S K G N L R E Y L Q A R R P P E E Q L S S K D L V S C A Y Q V A R G M E Y L A S K K C I H R D L A A R N V L V T E D N V M K I A D F G L I D Y Y K K T T N G R L P V K W M A P E A L F D R I Y T H Q S D V W S F G V L L W E I F T L G G S P Y P G V P V E E L F K L L K E G H R M D K P S N C T N E L Y M M M R D C W H A V P S Q R P T F K Q L V E D L D R I V A L T

AH

UNSTRUCTURED

2DWV

GSSGSSGPLEREGLPPGWERVESSEFGTYYVDHTNKRAQYRHPSGPSSGGSSGSSGPLEREGLPPGWERVESSEFGTYYVDHTNKRAQYRHPSGPSSG

~~SSS~~H~~SS~~~TTEEEEEETTTEEEEEETTTTEEESS~~~~~S~~~~SSS~~S~~S~~~~TTEEEEE~SSS~EEEEETTTTEEESS~~~~~~~~

G S S G S S G P L E R E G L P P G W E R V E S S E F G T Y Y V D H T N K R A Q Y R H P S G P S S G G S S G S S G P L E R E G L P P G W E R V E S S E F G T Y Y V D H T N K R A Q Y R H P S G P S S G

UNSTRUCTURED

BS

5DUP

RDCSVAGWLLGNPMCDEKANPANDLCYPGNFNDYEELKHLLSRINHFEKIQIIPKSSWSDHEASSGVSSACPYQGTPSFFRNVVWLIKKNNTYPTIKRSYNNTNQEDLLILWGIHHSNDAAEQTKLYQNPTTYISVGTSTLNQRLVPKIATRSKVNGQSGRMDFFWTILKPNDAINFESNGNFIAPEYAYKIVKKEVQLLESGGGLVQPGGSLRVSCTNSGFTFSNYAMSWVRQAPGKGLEWVSAISGTYYADSVKGRFTISRDNSKNTMYLQMNSLRAEDTAVYYCVRDDSYDGGGHYGLHNWFDSWGQGTLVTVSSSTKGPSVFPLAPSALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSTYICNVNHKPSNTKVDKKVEPSVLTQPPSVSGAPGQRVTISCTGSSSNIGAGYDVHWYQQLPGTAPKLLIYGNSNRPSGVPDRFSGSKSGTSASLAITGLQAEDEADYYCQSYDSSVVVFGGGTKLGTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR

~~B~SHHHHH~~TT~~~~SS~SBS~SS~S~BTTHHHHHHHHS~EEEEEEEES~~GGG~SSSB~S~~~EEEEEETTEEE~~SSEEE~B~BTTB~~~~~EEEE~~SSSEEEEEEEEEE~S~HHHHHHHTS~SS~~EEEE~SS~EEEE~~~~S~~~~BTTBS~EEEEEEEEE~TT~EEEEE~SSSEEEE~EEEEEEE~~~EEEE~~~~EE~TTEEEEEEEEEESS~GGGSEEEEEEE~TT~~EEEEEEE~~EEE~STTBTTEEEEEETTTTEEEEEEEEE~STT~EEEEEEEEE~TTTT~~~~SS~EEEEE~~~EEEEE~S~~~~~EEEEE~~~~EEEEEEEE~SS~~EEEEGGG~~~SS~EE~~~B~~TTS~EEEEEEE~~S~~~EEEEEEEGGGTEEEEEEE~~~~~~~~SB~~~~TT~~EEEEE~~~TTTTTTT~~~EEEEE~TTS~EEEEEBTTTB~~TTS~TTEEEEEETTEEEEEE~S~~TT~~SEEEEEE~SSSS~EE~~~BB~~~~B~~EEEEE~~~SHHHHHS~EEEEEEEEEEB~S~~EEE~EETTEE~~SSEEEEEE~~~SSS~~EEEEEEEEE~HHHHSS~~EEEEEEE~SS~SS~EEEEEE~

R D C S V A G W L L G N P M C D E K A N P A N D L C Y P G N F N D Y E E L K H L L S R I N H F E K I Q I I P K S S W S D H E A S S G V S S A C P Y Q G T P S F F R N V V W L I K K N N T Y P T I K R S Y N N T N Q E D L L I L W G I H H S N D A A E Q T K L Y Q N P T T Y I S V G T S T L N Q R L V P K I A T R S K V N G Q S G R M D F F W T I L K P N D A I N F E S N G N F I A P E Y A Y K I V K K E V Q L L E S G G G L V Q P G G S L R V S C T N S G F T F S N Y A M S W V R Q A P G K G L E W V S A I S G T Y Y A D S V K G R F T I S R D N S K N T M Y L Q M N S L R A E D T A V Y Y C V R D D S Y D G G G H Y G L H N W F D S W G Q G T L V T V S S S T K G P S V F P L A P S A L G C L V K D Y F P E P V T V S W N S G A L T S G V H T F P A V L Q S S G L Y S L S S V V T V P S S T Y I C N V N H K P S N T K V D K K V E P S V L T Q P P S V S G A P G Q R V T I S C T G S S S N I G A G Y D V H W Y Q Q L P G T A P K L L I Y G N S N R P S G V P D R F S G S K S G T S A S L A I T G L Q A E D E A D Y Y C Q S Y D S S V V V F G G G T K L G T V A A P S V F I F P P S D E Q L K S G T A S V V C L L N N F Y P R E A K V Q W K V D N A L Q S G N S Q E S V T E Q D S K D S T Y S L S S T L T L S K A D Y E K H K V Y A C E V T H Q G L S S P V T K S F N R

BS

UNSTRUCTURED

2WFO

ELPSLCMLNNSFYYMKGGANIFLIRVSDVSVLMKEYDVSVYEPEDLGNCLNKSDSSWAIHWFSIALGHDWLMDPPMLCRNKTKKEGSNIQFNISKADESRVYGKKIRNGMRHLFRGFYDPCEEGKVCYVTINQCGDPSSFEYCGTNYLSKCQF

~~~EEEESSSSEEEEEETTEEEEEEEES~~~~~TTTSEEE~SGGGGGGT~S~GGGHHHHHHHHHHHT~~TTTS~~EEE~~TT~TT~~~EEEE~~BSTTTHHHHHHHHHHHHHH~TT~~~~~~BTS~~EEEEEETTSGGGTTTTSHHHHTTS~~

E L P S L C M L N N S F Y Y M K G G A N I F L I R V S D V S V L M K E Y D V S V Y E P E D L G N C L N K S D S S W A I H W F S I A L G H D W L M D P P M L C R N K T K K E G S N I Q F N I S K A D E S R V Y G K K I R N G M R H L F R G F Y D P C E E G K V C Y V T I N Q C G D P S S F E Y C G T N Y L S K C Q F

BS

BS

1EO7

APDTSVSNKQNFSTDVIYQIFTDRFSDGNPANNPTGAAFDGTCTNLRLYCGGDWQGIINKINDGYLTGMGVTAIWISQPVENIYSIINYSGVNNTAYHGYWARDFKKTNPAYGTIADFQNLIAAAHAKNIKVIIDFAPNHTSPASSDQPSFAENGRLYDNGTLLGGYTNDTQNLFHHNGGTDFSTTENGIYKNLYDLADLNHNNSTVDVYLKDAIKMWLDLGIDGIRMAAVKHMPFGWQKSFMAAVNNYKPVFTFGAWFLGVNEVSPENHKFANESGMSLLDFRFAQKVRQVFRDNTDNMYGLKAMLEGSAADYAQVDDQVTFIDNHDMERFHASNANRRKLEQALAFTLTSRGVPAIYYGTEQYMSGGTDPDNRARIPSFSTSTTAYQVIQKLAPLRKSNPAIAYGSTQERWINNDVLIYERKFGSNVAVVAVNRNLNAPASISGLVTSLPQGSYNDVLGGLLNGNTLSVGSGGAASNFTLAAGGTAVWQYTAATATPTIGHVGPMMAKPGVTITIDGRGFGSSKGTVYFGTTAVSGADITSWEDTQIKVKIPAVAGGNYNIKVANAAGTASNVYDNFEVLSGDQVSVRFVVNNATTALGQNVYLTGSVSELGNWDPAKAIGPMYNQVVYQYPNWYYDVSVPAGKTIEFKFLKKQGSTVTWEGGSNHTFTAPSSGTATINVNWQP

~~TTSTT~TT~~TT~~EEEE~GGGT~~S~GGG~~~GGGB~TT~~STTSB~~~~HHHHHHHHHTTHHHHHT~~EEEE~~~EEE~~~~EESSS~EE~GGGS~SEEEEEEE~TTT~~HHHHHHHHHHHHHTT~EEEEEE~TTEEEE~~SS~TTSTTTT~EEETTEEEE~STT~TT~~B~~S~B~~SSSHHHHHSSBSTTEEEB~TTSHHHHHHHHHHHHHHHHTT~~EEEETTTTSS~HHHHHHHHHHHHTTS~~EEEE~~~~~TT~~~HHHHHHHHHSSSEEB~HHHHHHHHHHHTT~SS~HHHHHHHHHHHHHH~TTGGGSEE~S~~TTS~~S~~TTS~HHHHHHHHHHHHTSSSEEEEETTGGGT~~~~STTGGG~~~S~~~S~SHHHHHHHHHTTHHHH~HHHHT~~~EEEEE~SSEEEEEEEETTEEEEEEEE~~SS~~EEE~SEE~S~~SEEE~~TTTTTTS~~~EEE~GGGEE~~EEE~TT~EEEEEE~~~~~S~EEEEEE~SEE~TT~EEEEEEE~~~SS~~EEEETTEEEEGGG~~EE~SSEEEEE~~S~~SEEEEEEEE~TT~~B~~~EEEEEE~SSSEEEEEEEEES~~~~TT~EEEEEESSGGGTTT~GGG~B~~~B~SSSS~TT~EEEEEEEETT~EEEEEEEEEETTEEEE~~SS~EEEE~~SSS~EEEEEE~~~

A P D T S V S N K Q N F S T D V I Y Q I F T D R F S D G N P A N N P T G A A F D G T C T N L R L Y C G G D W Q G I I N K I N D G Y L T G M G V T A I W I S Q P V E N I Y S I I N Y S G V N N T A Y H G Y W A R D F K K T N P A Y G T I A D F Q N L I A A A H A K N I K V I I D F A P N H T S P A S S D Q P S F A E N G R L Y D N G T L L G G Y T N D T Q N L F H H N G G T D F S T T E N G I Y K N L Y D L A D L N H N N S T V D V Y L K D A I K M W L D L G I D G I R M A A V K H M P F G W Q K S F M A A V N N Y K P V F T F G A W F L G V N E V S P E N H K F A N E S G M S L L D F R F A Q K V R Q V F R D N T D N M Y G L K A M L E G S A A D Y A Q V D D Q V T F I D N H D M E R F H A S N A N R R K L E Q A L A F T L T S R G V P A I Y Y G T E Q Y M S G G T D P D N R A R I P S F S T S T T A Y Q V I Q K L A P L R K S N P A I A Y G S T Q E R W I N N D V L I Y E R K F G S N V A V V A V N R N L N A P A S I S G L V T S L P Q G S Y N D V L G G L L N G N T L S V G S G G A A S N F T L A A G G T A V W Q Y T A A T A T P T I G H V G P M M A K P G V T I T I D G R G F G S S K G T V Y F G T T A V S G A D I T S W E D T Q I K V K I P A V A G G N Y N I K V A N A A G T A S N V Y D N F E V L S G D Q V S V R F V V N N A T T A L G Q N V Y L T G S V S E L G N W D P A K A I G P M Y N Q V V Y Q Y P N W Y Y D V S V P A G K T I E F K F L K K Q G S T V T W E G G S N H T F T A P S S G T A T I N V N W Q P

BS

UNSTRUCTURED

5IC4

NSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIEHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIEKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIEKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYDEVDEVDEVDEV

~B~~~~SSEEEEEEEEE~~~~~GGGT~~~~TTHHHHHHHHHHHHHHTT~EEEEEES~~HHHHHHHHHHHHTS~~TTEEEEEEEEES~EETTEEEETTEEEEHHHHHGGGSTTT~GGGTTS~EEEEEES~~SSB~B~~B~~~B~TTTTEEEEESS~TTB~~~EETTTEEHHHHHHHHHHHHHTTTS~HHHHHHHHHHHHHHH~~~~~SSGGGTT~B~~~EEEEE~SSB~~~~~B~~~~SSEEEEEEEEE~~~~~TTTT~~~~TTHHHHHHHHHHHHHHTT~EEEEEES~~HHHHHHHHHHHHTS~~TTEEEEEEEEES~EETTEEEETTEEEEHHHHHHTTSTTT~GGGTTS~EEEEEES~~SSB~B~~B~~B~TTTTEEEEESS~TTB~~~EETTTEEHHHHHHHHHHHHHTTTS~HHHHHHHHHHHHHHH~~~~~SSGGGSS~B~~~EEEE~~SSB~~~~~B~~~~SSEEEEEEEEE~~~~~TTTT~~~~TTHHHHHHHHHHHHHHTT~EEEEEES~~HHHHHHHHHHHHTS~~TTEEEEEEEEES~EETTEEEETTEEEEHHHHHHTTSTTT~GGGTTS~EEEEEES~~~SB~B~~B~~B~TTTTEEEEESS~TTB~~~EETTTEEHHHHHHHHHHHHHTTTS~HHHHHHHHHHHHHHH~~~~~SSGGGSS~B~~~EEEEE~SSB~~~~~~~~~SSEEEEEEEEE~~~~~TTTT~~~~TTHHHHHHHHHHHHHTTT~EEEEEES~~HHHHHHHHHHHHTS~~TTEEEEEEEEES~EETTEEEETTEEEEHHHHHHTTSTTT~GGGTTS~EEEEEES~~SSB~B~~B~~~~B~TTTTEEEEESS~TTB~~~EETTTEEHHHHHHHHHHHHHTTTS~HHHHHHHHHHHHHHH~~~~~SSGGGTT~B~~~EEEE~~SS~~~~~~B~~B~~B~~B~

N S Y K M D Y P E M G L C I I I N N K N F H K S T G M T S R S G T D V D A A N L R E T F R N L K Y E V R N K N D L T R E E I V E L M R D V S K E D H S K R S S F V C V L L S H G E E G I I F G T N G P V D L K K I T N F F R G D R C R S L T G K P K L F I I Q A C R G T E L D C G I E H K I P V E A D F L Y A Y S T A P G Y Y S W R N S K D G S W F I Q S L C A M L K Q Y A D K L E F M H I L T R V N R K V A T E F E S F S F D A T F H A K K Q I P C I V S M L T K E L Y F Y N S Y K M D Y P E M G L C I I I N N K N F H K S T G M T S R S G T D V D A A N L R E T F R N L K Y E V R N K N D L T R E E I V E L M R D V S K E D H S K R S S F V C V L L S H G E E G I I F G T N G P V D L K K I T N F F R G D R C R S L T G K P K L F I I Q A C R G T E L D C G I E K I P V E A D F L Y A Y S T A P G Y Y S W R N S K D G S W F I Q S L C A M L K Q Y A D K L E F M H I L T R V N R K V A T E F E S F S F D A T F H A K K Q I P C I V S M L T K E L Y F Y N S Y K M D Y P E M G L C I I I N N K N F H K S T G M T S R S G T D V D A A N L R E T F R N L K Y E V R N K N D L T R E E I V E L M R D V S K E D H S K R S S F V C V L L S H G E E G I I F G T N G P V D L K K I T N F F R G D R C R S L T G K P K L F I I Q A C R G T E L D C G I E K I P V E A D F L Y A Y S T A P G Y Y S W R N S K D G S W F I Q S L C A M L K Q Y A D K L E F M H I L T R V N R K V A T E F E S F S F D A T F H A K K Q I P C I V S M L T K E L Y F Y S Y K M D Y P E M G L C I I I N N K N F H K S T G M T S R S G T D V D A A N L R E T F R N L K Y E V R N K N D L T R E E I V E L M R D V S K E D H S K R S S F V C V L L S H G E E G I I F G T N G P V D L K K I T N F F R G D R C R S L T G K P K L F I I Q A C R G T E L D C G I E T H K I P V E A D F L Y A Y S T A P G Y Y S W R N S K D G S W F I Q S L C A M L K Q Y A D K L E F M H I L T R V N R K V A T E F E S F S F D A T F H A K K Q I P C I V S M L T K E L Y F Y D E V D E V D E V D E V

AH

BS

3R6Y

VRIEKDFLGEKEIPKDAYYGVQTIRATENFPITGYRIHPELIKSLGIVKKSAALANMEVGLLDKEVGQYIVKAADEVIEGKWNDQFIVDPIQGGAGTSINMNANEVIANRALELMGEEKGNYSKISPNSHVNMSQSTNDAFPTATHIAVLSLLNQLIETTKYMQQEFMKKADEFAGVIKMGRTHLQDAVPILLGQEFEAYARVIARDIERIANTRNNLYDINMGATAVGTGLNADPEYISIVTEHLAKFSGHPLRSAQHLVDATQNTDCYTEVSSALKVCMINMSKIANDLRLMASGPRAGLSEIVLPARQPGSSIMPGKVNPVMPEVMNQVAFQVFGNDLTITSASEAGQFELNVMEPVLFFNLIQSISIMTNVFKSFTENCLKGIKANVRIEKDFLGEKEIPKDAYYGVQTIRATENFPITGYRIHPELIKSLGIVKKSAALANMEVGLLDKEVGQYIVKAADEVIEGKWNDQFIVDPIQGGAGTSINMNANEVIANRALELMGEEKGNYSKISPNSHVNMSQSTNDAFPTATHIAVLSLLNQLIETTKYMQQEFMKKADEFAGVIKMGRTHLQDAVPILLGQEFEAYARVIARDIERIANTRNNLYDINMGATAVGTGLNADPEYISIVTEHLAKFSGHPLRSAQHLVDATQNTDCYTEVSSALKVCMINMSKIANDLRLMASGPRAGLSEIVLPARQPGSSIMPGKVNPVMPEVMNQVAFQVFGNDLTITSASEAGQFELNVMEPVLFFNLIQSISIMTNVFKSFTENCLKGIKANVRIEKDFLGEKEIPKDAYYGVQTIRATENFPITGYRIHPELIKSLGIVKKSAALANMEVGLLDKEVGQYIVKAADEVIEGKWNDQFIVDPIQGGAGTSINMNANEVIANRALELMGEEKGNYSKISPNSHVNMSQSTNDAFPTATHIAVLSLLNQLIETTKYMQQEFMKKADEFAGVIKMGRTHLQDAVPILLGQEFEAYARVIARDIERIANTRNNLYDINMGATAVGTGLNADPEYISIVTEHLAKFSGHPLRSAQHLVDATQNTDCYTEVSSALKVCMINMSKIANDLRLMASGPRAGLSEIVLPARQPGVNPVMPEVMNQVAFQVFGNDLTITSASEAGQFELNVMEPVLFFNLIQSISIMTNVFKSFTENCLKGIKANVRIEKDFLGEKEIPKDAYYGVQTIRATENFPITGYRIHPELIKSLGIVKKSAALANMEVGLLDKEVGQYIVKAADEVIEGKWNDQFIVDPIQGGAGTSINMNANEVIANRALELMGEEKGNYSKISPNSHVNMSQSTNDAFPTATHIAVLSLLNQLIETTKYMQQEFMKKADEFAGVIKMGRTHLQDAVPILLGQEFEAYARVIARDIERIANTRNNLYDINMGATAVGTGLNADPEYISIVTEHLAKFSGHPLRSAQHLVDATQNTDCYTEVSSALKVCMINMSKIANDLRLMASGPRAGLSEIVLPARQPGSSIMPGKVNPVMPEVMNQVAFQVFGNDLTITSASEAGQFELNVMEPVLFFNLIQSISIMTNVFKSFTENCLKGIKANVRIEKDFLGEKEIPKDAYYGVQTIRATENFPITGYRIHPELIKSLGIVKKSAALANMEVGLLDKEVGQYIVKAADEVIEGKWNDQFIVDPIQGGAGTSINMNANEVIANRALELMGEEKGNYSKISPNSHVNMSQSTNDAFPTATHIAVLSLLNQLIETTKYMQQEFMKKADEFAGVIKMGRTHLQDAVPILLGQEFEAYARVIARDIERIANTRNNLYDINMGATAVGTGLNADPEYISIVTEHLAKFSGHPLRSAQHLVDATQNTDCYTEVSSALKVCMINMSKIANDLRLMASGPRAGLSEIVLPARQPGSSIMPGKVNPVMPEVMNQVAFQVFGNDLTITSASEAGQFELNVMEPVLFFNLIQSISIMTNVFKSFTENCLKGIKANEVRIEKDFLGEKEIPKDAYYGVQTIRATENFPITGYRIHPELIKSLGIVKKSAALANMEVGLLDKEVGQYIVKAADEVIEGKWNDQFIVDPIQGGAGTSINMNANEVIANRALELMGEEKGNYSKISPNSHVNMSQSTNDAFPTATHIAVLSLLNQLIETTKYMQQEFMKKADEFAGVIKMGRTHLQDAVPILLGQEFEAYARVIARDIERIANTRNNLYDINMGATAVGTGLNADPEYISIVTEHLAKFSGHPLRSAQHLVDATQNTDCYTEVSSALKVCMINMSKIANDLRLMASGPRAGLSEIVLPARQPGSSIMPGKVNPVMPEVMNQVAFQVFGNDLTITSASEAGQFELNVMEPVLFFNLIQSISIMTNVFKSFTENCLKGIKANVRIEKDFLGEKEIPKDAYYGVQTIRATENFPITGYRIHPELIKSLGIVKKSAALANMEVGLLDKEVGQYIVKAADEVIEGKWNDQFIVDPIQGGAGTSINMNANEVIANRALELMGEEKGNYSKISPNSHVNMSQSTNDAFPTATHIAVLSLLNQLIETTKYMQQEFMKKADEFAGVIKMGRTHLQDAVPILLGQEFEAYARVIARDIERIANTRNNLYDINMGATAVGTGLNADPEYISIVTEHLAKFSGHPLRSAQHLVDATQNTDCYTEVSSALKVCMINMSKIANDLRLMASGPRAGLSEIVLPARQPGVNPVMPEVMNQVAFQVFGNDLTITSASEAGQFELNVMEPVLFFNLIQSISIMTNVFKSFTENCLKGIKANEVRIEKDFLGEKEIPKDAYYGVQTIRATENFPITGYRIHPELIKSLGIVKKSAALANMEVGLLDKEVGQYIVKAADEVIEGKWNDQFIVDPIQGGAGTSINMNANEVIANRALELMGEEKGNYSKISPNSHVNMSQSTNDAFPTATHIAVLSLLNQLIETTKYMQQEFMKKADEFAGVIKMGRTHLQDAVPILLGQEFEAYARVIARDIERIANTRNNLYDINMGATAVGTGLNADPEYISIVTEHLAKFSGHPLRSAQHLVDATQNTDCYTEVSSALKVCMINMSKIANDLRLMASGPRAGLSEIVLPARQPGSSIMPGKVNPVMPEVMNQVAFQVFGNDLTITSASEAGQFELNVMEPVLFFNLIQSISIMTNVFKSFTENCLKGIKAN

~~~EE~SS~EE~~~TT~~~~HHHHHHHHH~~SS~~~~~HHHHHHHHHHHHHHHHHHHHTTSS~HHHHHHHHHHHHHHHTTS~STT~~~~SS~SSTTHHHHHHHHHHHHHHHHHHTT~~TT~TTTS~IIIIITTT~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTT~EEEEEETTEEEEEEEHHHHHHHHHHHHHHHHHHHHTTSHHHHEE~TT~TTTSS~SS~~HHHHHHHHHHHHHHHTS~~EE~S~HHHHHH~~HHHHHHHHHHHHHHHHHHHHHHHHHHHT~BSSSS~~~EE~~~~S~~~SSSTT~~~~HHHHHHHHHHHHHHHHHHHHHHHHHH~BTTB~TTHHHHHHHHHHHHHHHHHHHHHHHHHTGGG~EE~~~~EE~SS~EE~~~SS~S~~HHHHHHHHH~~SS~~~~~HHHHHHHHHHHHHHHHHHHHHT~S~HHHHHHHHHHHHHHHTTTTTTT~~S~SS~SSTTHHHHHHHHHHHHHHHHHHTT~~SS~TTTS~TTTTTTTT~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS~EEEEEETTEEEEEEEHHHHHHHHHHHHHHHHHHHHHTTHHHH~~~TT~TTTSS~SS~~HHHHHHHHHHHHHHH~S~~~~~S~TTHHHH~~HHHHHHHHHHHHHHHHHHHHHHHHHHHT~BSSSS~~~EE~~~~S~~~SS~TT~~~~HHHHHHHHHHHHHHHHHHHHHHHHHT~BTTB~TTHHHHHHHHHHHHHHHHHHHHHHHHTTTTT~EE~~~~EE~SS~EE~~~TT~~~~HHHHHHHHH~~SS~~~~~HHHHHHHHHHHHHHHHHHHHTT~S~HHHHHHHHHHHHHHHTTS~SSS~~~~SS~SGGGHHHHHHHHHHHHHHHHHHTT~~TT~TTTS~IIIIITTT~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS~EEEEEETTEEEEEEEHHHHHHHHHHHHHHHHHHHHTTSHHHHEE~TT~TTTSS~SS~~HHHHHHHHHHHHHHH~S~~EE~SSTTHHHH~~HHHHHHHHHHHHHHHHHHHHHHHHHHHT~BSSSS~~~EE~~~~S~~~~~HHHHHHHHHHHHHHHHHHHHHHHHHT~BTTB~TTHHHHHHHHHHHHHHHHHHHHHHHHTTGGG~EE~~~~EE~SS~EE~~~TT~~~~HHHHHHHHH~~SS~~~~~HHHHHHHHHHHHHHHHHHHHTTSS~TTHHHHHHHHHHHHHTTTTSTT~~S~SS~SSTTHHHHHHHHHHHHHHHHHHTT~~TT~TTTS~IIIIITTT~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS~EE~~EETTEE~S~EEHHHHHHHHHHHHHHHHHHHHHTTHHHHEE~TT~TTTSS~SS~~HHHHHHHHHHHHHHHSS~~EE~S~TTHHHH~~HHHHHHHHHHHHHHHHHHHHHHHHHHHT~BSSSS~~~EE~~~~~~~~SSSTT~~~~HHHHHHHHHHHHHHHHHHHHHHHHHT~BTTB~TTHHHHHHHHHHHHHHHHHHHHHHHHTTGGG~EE~~~~EE~SS~EE~~~TT~~~~HHHHHHHHH~~SS~~~~~HHHHHHHHHHHHHHHHHHHHTT~S~HHHHHHHHHHHHHHHTTSS~TT~~~~SS~SGGGHHHHHHHHHHHHHHHHHHTT~~TT~TTTS~TTTTTTTT~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTT~EEEEEETTEEEEEEEHHHHHHHHHHHHHHHHHHHHHTTGGGSEE~TT~TTTSS~SS~~HHHHHHHHHHHHHHH~S~~EE~S~HHHHHH~~HHHHHHHHHHHHHHHHHHHHHHHHHHHT~BSSSS~~~EE~~~~S~~~SSSTT~~~~HHHHHHHHHHHHHHHHHHHHHHHHHH~BTTB~TTHHHHHHHHHHHHHHHHHHHHHHHHHTTTT~EE~~~~~~B~SS~B~~~~TT~~~~HHHHHHHHH~~SS~~~~~HHHHHHHHHHHHHHHHHHHHHTSS~HHHHHHHHHHHHHHTTTTTGGG~~~~SS~SSTTHHHHHHHHHHHHHHHHHHTT~~SS~TTTS~IIIIITTT~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS~EEEEEETTEEEEEEEHHHHHHHHHHHHHHHHHHHHHTTGGGSEE~TT~TTTSS~SS~~HHHHHHHHHHHHHHT~S~~EE~SSTTHHHH~~HHHHHHHHHHHHHHHHHHHHHHHHHHHT~BSSSS~~~EE~~~~S~~~SSSSS~~~~HHHHHHHHHHHHHHHHHHHHHHHHHT~BTTB~TTHHHHHHHHHHHHHHHHHHHHHHHHHTGGG~EE~~~~EE~SS~EE~~~TT~S~~HHHHHHHHH~~SS~~~~~HHHHHHHHHHHHHHHHHHHHTTSS~HHHHHHHHHHHHHHHTTTTTTT~~~~SS~SGGGHHHHHHHHHHHHHHHHHHTT~~TT~TTTS~IIIIITTT~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSS~EEEEEETTEEEEEEEHHHHHHHHHHHHHHHHHHHHTTSGGGSEE~TT~TTTSS~SS~~HHHHHHHHHHHHHHH~S~~EE~SSTTHHHH~~HHHHHHHHHHHHHHHHHHHHHHHHHHHT~BSSSS~~~EE~~~~S~~~~~HHHHHHHHHHHHHHHHHHHHHHHHHH~BTTB~TTHHHHHHHHHHHHHHHHHHHHHHHHHTGGG~EE~~~~~EE~SS~EE~~~TT~~~~HHHHHHHHH~~SS~~~~~HHHHHHHHHHHHHHHHHHHHHTSS~HHHHHHHHHHHHHHHTTTTSTT~~S~SS~SSTTHHHHHHHHHHHHHHHHHHTT~~TT~TTTS~IIIIITTT~~HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS~EEEEEETTEEEEEEEHHHHHHHHHHHHHHHHHHHHHTTTTTSEE~TT~TTTSS~SS~~HHHHHHHHHHHHHHHTS~~EE~S~HHHHHH~~HHHHHHHHHHHHHHHHHHHHHHHHHHHT~BSSSS~~~EE~~~~~~~~SSSTT~~~~HHHHHHHHHHHHHHHHHHHHHHHHHT~BTTB~TTHHHHHHHHHHHHHHHHHHHHHHHHHTGGG~EE~

V R I E K D F L G E K E I P K D A Y Y G V Q T I R A T E N F P I T G Y R I H P E L I K S L G I V K K S A A L A N M E V G L L D K E V G Q Y I V K A A D E V I E G K W N D Q F I V D P I Q G G A G T S I N M N A N E V I A N R A L E L M G E E K G N Y S K I S P N S H V N M S Q S T N D A F P T A T H I A V L S L L N Q L I E T T K Y M Q Q E F M K K A D E F A G V I K M G R T H L Q D A V P I L L G Q E F E A Y A R V I A R D I E R I A N T R N N L Y D I N M G A T A V G T G L N A D P E Y I S I V T E H L A K F S G H P L R S A Q H L V D A T Q N T D C Y T E V S S A L K V C M I N M S K I A N D L R L M A S G P R A G L S E I V L P A R Q P G S S I M P G K V N P V M P E V M N Q V A F Q V F G N D L T I T S A S E A G Q F E L N V M E P V L F F N L I Q S I S I M T N V F K S F T E N C L K G I K A N V R I E K D F L G E K E I P K D A Y Y G V Q T I R A T E N F P I T G Y R I H P E L I K S L G I V K K S A A L A N M E V G L L D K E V G Q Y I V K A A D E V I E G K W N D Q F I V D P I Q G G A G T S I N M N A N E V I A N R A L E L M G E E K G N Y S K I S P N S H V N M S Q S T N D A F P T A T H I A V L S L L N Q L I E T T K Y M Q Q E F M K K A D E F A G V I K M G R T H L Q D A V P I L L G Q E F E A Y A R V I A R D I E R I A N T R N N L Y D I N M G A T A V G T G L N A D P E Y I S I V T E H L A K F S G H P L R S A Q H L V D A T Q N T D C Y T E V S S A L K V C M I N M S K I A N D L R L M A S G P R A G L S E I V L P A R Q P G S S I M P G K V N P V M P E V M N Q V A F Q V F G N D L T I T S A S E A G Q F E L N V M E P V L F F N L I Q S I S I M T N V F K S F T E N C L K G I K A N V R I E K D F L G E K E I P K D A Y Y G V Q T I R A T E N F P I T G Y R I H P E L I K S L G I V K K S A A L A N M E V G L L D K E V G Q Y I V K A A D E V I E G K W N D Q F I V D P I Q G G A G T S I N M N A N E V I A N R A L E L M G E E K G N Y S K I S P N S H V N M S Q S T N D A F P T A T H I A V L S L L N Q L I E T T K Y M Q Q E F M K K A D E F A G V I K M G R T H L Q D A V P I L L G Q E F E A Y A R V I A R D I E R I A N T R N N L Y D I N M G A T A V G T G L N A D P E Y I S I V T E H L A K F S G H P L R S A Q H L V D A T Q N T D C Y T E V S S A L K V C M I N M S K I A N D L R L M A S G P R A G L S E I V L P A R Q P G V N P V M P E V M N Q V A F Q V F G N D L T I T S A S E A G Q F E L N V M E P V L F F N L I Q S I S I M T N V F K S F T E N C L K G I K A N V R I E K D F L G E K E I P K D A Y Y G V Q T I R A T E N F P I T G Y R I H P E L I K S L G I V K K S A A L A N M E V G L L D K E V G Q Y I V K A A D E V I E G K W N D Q F I V D P I Q G G A G T S I N M N A N E V I A N R A L E L M G E E K G N Y S K I S P N S H V N M S Q S T N D A F P T A T H I A V L S L L N Q L I E T T K Y M Q Q E F M K K A D E F A G V I K M G R T H L Q D A V P I L L G Q E F E A Y A R V I A R D I E R I A N T R N N L Y D I N M G A T A V G T G L N A D P E Y I S I V T E H L A K F S G H P L R S A Q H L V D A T Q N T D C Y T E V S S A L K V C M I N M S K I A N D L R L M A S G P R A G L S E I V L P A R Q P G S S I M P G K V N P V M P E V M N Q V A F Q V F G N D L T I T S A S E A G Q F E L N V M E P V L F F N L I Q S I S I M T N V F K S F T E N C L K G I K A N V R I E K D F L G E K E I P K D A Y Y G V Q T I R A T E N F P I T G Y R I H P E L I K S L G I V K K S A A L A N M E V G L L D K E V G Q Y I V K A A D E V I E G K W N D Q F I V D P I Q G G A G T S I N M N A N E V I A N R A L E L M G E E K G N Y S K I S P N S H V N M S Q S T N D A F P T A T H I A V L S L L N Q L I E T T K Y M Q Q E F M K K A D E F A G V I K M G R T H L Q D A V P I L L G Q E F E A Y A R V I A R D I E R I A N T R N N L Y D I N M G A T A V G T G L N A D P E Y I S I V T E H L A K F S G H P L R S A Q H L V D A T Q N T D C Y T E V S S A L K V C M I N M S K I A N D L R L M A S G P R A G L S E I V L P A R Q P G S S I M P G K V N P V M P E V M N Q V A F Q V F G N D L T I T S A S E A G Q F E L N V M E P V L F F N L I Q S I S I M T N V F K S F T E N C L K G I K A N E V R I E K D F L G E K E I P K D A Y Y G V Q T I R A T E N F P I T G Y R I H P E L I K S L G I V K K S A A L A N M E V G L L D K E V G Q Y I V K A A D E V I E G K W N D Q F I V D P I Q G G A G T S I N M N A N E V I A N R A L E L M G E E K G N Y S K I S P N S H V N M S Q S T N D A F P T A T H I A V L S L L N Q L I E T T K Y M Q Q E F M K K A D E F A G V I K M G R T H L Q D A V P I L L G Q E F E A Y A R V I A R D I E R I A N T R N N L Y D I N M G A T A V G T G L N A D P E Y I S I V T E H L A K F S G H P L R S A Q H L V D A T Q N T D C Y T E V S S A L K V C M I N M S K I A N D L R L M A S G P R A G L S E I V L P A R Q P G S S I M P G K V N P V M P E V M N Q V A F Q V F G N D L T I T S A S E A G Q F E L N V M E P V L F F N L I Q S I S I M T N V F K S F T E N C L K G I K A N V R I E K D F L G E K E I P K D A Y Y G V Q T I R A T E N F P I T G Y R I H P E L I K S L G I V K K S A A L A N M E V G L L D K E V G Q Y I V K A A D E V I E G K W N D Q F I V D P I Q G G A G T S I N M N A N E V I A N R A L E L M G E E K G N Y S K I S P N S H V N M S Q S T N D A F P T A T H I A V L S L L N Q L I E T T K Y M Q Q E F M K K A D E F A G V I K M G R T H L Q D A V P I L L G Q E F E A Y A R V I A R D I E R I A N T R N N L Y D I N M G A T A V G T G L N A D P E Y I S I V T E H L A K F S G H P L R S A Q H L V D A T Q N T D C Y T E V S S A L K V C M I N M S K I A N D L R L M A S G P R A G L S E I V L P A R Q P G V N P V M P E V M N Q V A F Q V F G N D L T I T S A S E A G Q F E L N V M E P V L F F N L I Q S I S I M T N V F K S F T E N C L K G I K A N E V R I E K D F L G E K E I P K D A Y Y G V Q T I R A T E N F P I T G Y R I H P E L I K S L G I V K K S A A L A N M E V G L L D K E V G Q Y I V K A A D E V I E G K W N D Q F I V D P I Q G G A G T S I N M N A N E V I A N R A L E L M G E E K G N Y S K I S P N S H V N M S Q S T N D A F P T A T H I A V L S L L N Q L I E T T K Y M Q Q E F M K K A D E F A G V I K M G R T H L Q D A V P I L L G Q E F E A Y A R V I A R D I E R I A N T R N N L Y D I N M G A T A V G T G L N A D P E Y I S I V T E H L A K F S G H P L R S A Q H L V D A T Q N T D C Y T E V S S A L K V C M I N M S K I A N D L R L M A S G P R A G L S E I V L P A R Q P G S S I M P G K V N P V M P E V M N Q V A F Q V F G N D L T I T S A S E A G Q F E L N V M E P V L F F N L I Q S I S I M T N V F K S F T E N C L K G I K A N

AH

UNSTRUCTURED

5OB0

TFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLTTGETGYIPSNYVAPSDAPPLPPRNRPRL

~EEESS~B~~SHTTB~~B~TT~EEEEEE~SSSSEEEEEETTT~~EEEEEGGGEEE~~~~~~~~~~~~~~

T F V A L Y D Y E S R T E T D L S F K K G E R L Q I V N N T E G D W W L A H S L T T G E T G Y I P S N Y V A P S D A P P L P P R N R P R L

UNSTRUCTURED

BS

2I47

PMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS

~~~~EEEEEEEE~HHHHHHTSTT~HHHHHHHHHHHHHHHHHHHHT~~TTSSS~~~~EEEEEEEEE~~S~~~~~TT~~~TT~SS~SS~TTSSS~~HHHHHHHHHHHTHHHHTTSSEEEEEE~~~~GGG~~EEE~~~~S~TT~~SSSS~~~EEETTTTEEE~~~EEEEESEETTEE~~HHHHHHHHHHHHHHHTT~~~~~~STTSSS~~GGGT~~~TT~SS~~~S~SGGGGS~~HHHHHHHHHHHHHHHHHH~B~~~~~~EEEEEEEE~HHHHHHTSTT~HHHHHHHHHHHHHHHHHHHHT~~TTSSS~~~~EEEEEEEEE~~S~~~~~TT~~~TT~SS~SS~TTSSS~~HHHHHHHHHHHTHHHHTTSSEEEEEE~~~~GGG~~EEE~~~~S~TT~~SSSS~~~EEETTTTEEE~~~EEEEESEETTEE~~HHHHHHHHHHHHHHHTT~~~~~~STT~SS~~TTTT~~~TT~SS~~~S~STTTTS~~HHHHHHHHHHHHHHHHHH~B~~~~EEEEEEEEEE~HHHHHHTSTT~HHHHHHHHHHHHHHHHHHHHT~~TTSSS~~~~EEEEEEEEE~~S~~~~~TT~~~TT~SS~SS~SSSSS~~HHHHHHHHHHHTHHHHTTSSEEEEEE~~~~GGG~~EEE~~~~S~TT~~SSSS~~~EEETTTTEEE~~~EEEEE~EETTEE~~HHHHHHHHHHHHHHHTT~~~~~SSSSTTS~~GGGT~~~TT~SS~~~S~SGGGGS~~HHHHHHHHHHHHHHHHHH~EE~~~~~~EEEEEEEE~HHHHHHTSTT~HHHHHHHHHHHHHHHHHHHHT~~TTSSS~~~~EEEEEEEEE~~S~B~~~TT~~~TTBSS~SS~TTSSS~~HHHHHHHHHHHHHHHHTTSSEEEEEE~~~~GGG~~EEE~~~~S~TT~~SSSS~~~EE~TTTSSEE~~~EEEEE~EETTEE~~HHHHHHHHHHHHHHHTT~~~~~S~TTTSS~~GGGT~~~TT~SS~~~S~SGGGGS~~HHHHHHHHHHHHHHHHHH~B~~~

P M K N T C K L L V V A D H R F Y R Y M G R G E E S T T T N Y L I E L I D R V D D I Y R N T A W D N A G F K G Y G I Q I E Q I R I L K S P Q E V K P G E K H Y N M A K S Y P N E E K D A W D V K M L L E Q F S F D I A E E A S K V C L A H L F T Y Q D F D M G T L G L A Y V G S P R A N S H G G V C P K A Y Y S P V G K K N I Y L N S G L T S T K N Y G K T I L T K E A D L V T T H E L G H N F G A E H D P D G L A E C A P N E D Q G G K Y V M Y P I A V S G D H E N N K M F S Q C S K Q S I Y K T I E S K A Q E C F Q E R S M K N T C K L L V V A D H R F Y R Y M G R G E E S T T T N Y L I E L I D R V D D I Y R N T A W D N A G F K G Y G I Q I E Q I R I L K S P Q E V K P G E K H Y N M A K S Y P N E E K D A W D V K M L L E Q F S F D I A E E A S K V C L A H L F T Y Q D F D M G T L G L A Y V G S P R A N S H G G V C P K A Y Y S P V G K K N I Y L N S G L T S T K N Y G K T I L T K E A D L V T T H E L G H N F G A E H D P D G L A E C A P N E D Q G G K Y V M Y P I A V S G D H E N N K M F S Q C S K Q S I Y K T I E S K A Q E C F Q E R S M K N T C K L L V V A D H R F Y R Y M G R G E E S T T T N Y L I E L I D R V D D I Y R N T A W D N A G F K G Y G I Q I E Q I R I L K S P Q E V K P G E K H Y N M A K S Y P N E E K D A W D V K M L L E Q F S F D I A E E A S K V C L A H L F T Y Q D F D M G T L G L A Y V G S P R A N S H G G V C P K A Y Y S P V G K K N I Y L N S G L T S T K N Y G K T I L T K E A D L V T T H E L G H N F G A E H D P D G L A E C A P N E D Q G G K Y V M Y P I A V S G D H E N N K M F S Q C S K Q S I Y K T I E S K A Q E C F Q E R S P M K N T C K L L V V A D H R F Y R Y M G R G E E S T T T N Y L I E L I D R V D D I Y R N T A W D N A G F K G Y G I Q I E Q I R I L K S P Q E V K P G E K H Y N M A K S Y P N E E K D A W D V K M L L E Q F S F D I A E E A S K V C L A H L F T Y Q D F D M G T L G L A Y V G S P R A N S H G G V C P K A Y Y S P V G K K N I Y L N S G L T S T K N Y G K T I L T K E A D L V T T H E L G H N F G A E H D P D G L A E C A P N E D Q G G K Y V M Y P I A V S G D H E N N K M F S Q C S K Q S I Y K T I E S K A Q E C F Q E R S

AH

UNSTRUCTURED

4I25

SQLLNYIDGNFVTSASSFANINPVNGKLISDVFEADAKQVNEAVVAAQNALKGPWGKLSVQDRAALIHKIADGIQARFEEFVAAEVADTGRPVHQARTLDIPRAIANFRTFADLAKTSHTDLFEMSTSDGSGALNYTVRKPLGVIGVISPWNLPLLLFTWKVAPALACGNTVVAKPSEESPSSATLLAEVMHDAGVPPGVFNLIHGFGKDSAGEFLTQHPGISALTFTGESKTGSTIMKAVADGVKEVSFELGGKNAAVVFADADLDAAIEGVLRSSFTNSGQVCLCSERVYVHRSIFDEFVSGLKVEAERLVVGYPDQDGVNMGPLISHGHRDKVLSYYRLAVDEGATVVTGGGVPKFNDERDQGAYVQPTIWTGLSDKARCVTEEIFGPVCHISPFDDEDEVINRVNDSNYGLACAIWTTNLSRAHRVSRQIHVGLVWVNTWYLRDLRTPFGGVKLSGLGREGGRFSMDFYSDIANICIKISQLLNYIDGNFVTSASSFANINPVNGKLISDVFEADAKQVNEAVVAAQNALKGPWGKLSVQDRAALIHKIADGIQARFEEFVAAEVADTGRPVHQARTLDIPRAIANFRTFADLAKTSHTDLFEMSTSDGSGALNYTVRKPLGVIGVISPWNLPLLLFTWKVAPALACGNTVVAKPSEESPSSATLLAEVMHDAGVPPGVFNLIHGFGKDSAGEFLTQHPGISALTFTGESKTGSTIMKAVADGVKEVSFELGGKNAAVVFADADLDAAIEGVLRSSFTNSGQVCLCSERVYVHRSIFDEFVSGLKVEAERLVVGYPDQDGVNMGPLISHGHRDKVLSYYRLAVDEGATVVTGGGVPKFNDERDQGAYVQPTIWTGLSDKARCVTEEIFGPVCHISPFDDEDEVINRVNDSNYGLACAIWTTNLSRAHRVSRQIHVGLVWVNTWYLRDLRTPFGGVKLSGLGREGGRFSMDFYSDIANICIKISQLLNYIDGNFVTSASSFANINPVNGKLISDVFEADAKQVNEAVVAAQNALKGPWGKLSVQDRAALIHKIADGIQARFEEFVAAEVADTGRPVHQARTLDIPRAIANFRTFADLAKTSHTDLFEMSTSDGSGALNYTVRKPLGVIGVISPWNLPLLLFTWKVAPALACGNTVVAKPSEESPSSATLLAEVMHDAGVPPGVFNLIHGFGKDSAGEFLTQHPGISALTFTGESKTGSTIMKAVADGVKEVSFELGGKNAAVVFADADLDAAIEGVLRSSFTNSGQVCLCSERVYVHRSIFDEFVSGLKVEAERLVVGYPDQDGVNMGPLISHGHRDKVLSYYRLAVDEGATVVTGGGVPKFNDERDQGAYVQPTIWTGLSDKARCVTEEIFGPVCHISPFDDEDEVINRVNDSNYGLACAIWTTNLSRAHRVSRQIHVGLVWVNTWYLRDLRTPFGGVKLSGLGREGGRFSMDFYSDIANICIKISQLLNYIDGNFVTSASSFANINPVNGKLISDVFEADAKQVNEAVVAAQNALKGPWGKLSVQDRAALIHKIADGIQARFEEFVAAEVADTGRPVHQARTLDIPRAIANFRTFADLAKTSHTDLFEMSTSDGSGALNYTVRKPLGVIGVISPWNLPLLLFTWKVAPALACGNTVVAKPSEESPSSATLLAEVMHDAGVPPGVFNLIHGFGKDSAGEFLTQHPGISALTFTGESKTGSTIMKAVADGVKEVSFELGGKNAAVVFADADLDAAIEGVLRSSFTNSGQVCLCSERVYVHRSIFDEFVSGLKVEAERLVVGYPDQDGVNMGPLISHGHRDKVLSYYRLAVDEGATVVTGGGVPKFNDERDQGAYVQPTIWTGLSDKARCVTEEIFGPVCHISPFDDEDEVINRVNDSNYGLACAIWTTNLSRAHRVSRQIHVGLVWVNTWYLRDLRTPFGGVKLSGLGREGGRFSMDFYSDIANICIKI

~EE~EEETTEEE~~SEEEEEE~TTT~~EEEEEEE~~HHHHHHHHHHHHHHTTSHHHH~~HHHHHHHHHHHHHHHHTTHHHHHHHHHHHH~~~HHHHHHTHHHHHHHHHHHHHHHHHH~~EEEEEE~~TTSS~EEEEEEEEE~SEEEEE~~SSSHHHHHHHHHHHHHHTT~EEEEE~~TTS~HHHHHHHHHHHHTT~~TTSEEE~~~~STTSHHHHHHH~TT~SEEEEES~HHHHHHHHHHHGGGT~EEEEE~~~~EEEEE~TTS~HHHHHHHHHHHHHGGGG~STT~EEEEEEEHHHHHHHHHHHHHHHHH~~BS~TTSTT~~B~~~S~HHHHHHHHHHHHHHHHTT~EEEE~~S~~~~SSGGGGS~~~~~EEEE~~~TTSHHHHS~~~SSEEEEEEE~~HHHHHHHHH~SSEESEEEEE~~BHHHHHHHHTTS~SSEEEESSSS~~~TTS~B~~EETTEES~BSHHHHHHHTEEEEEEEEE~~~B~EEETTEEE~~SEEEEEE~TTT~~EEEEEEE~~HHHHHHHHHHHHHHTTSHHHH~~HHHHHHHHHHHHHHHHHTHHHHHHHHHHHH~~~HHHHHHTHHHHHHHHHHHHHHHHHH~~EEEEEE~~TTSS~EEEEEEEEE~SEEEEE~~SSSHHHHHHHHHHHHHHTT~EEEEE~~TT~~HHHHHHHHHHHHHT~~TTTEEE~~~~STTSHHHHHHH~TT~SEEEEES~HHHHHHHHHHTGGGT~EEEEE~~~~EEEEE~TTS~HHHHHHHHHHHHHGGGG~STT~EEEEEEETTTHHHHHHHHHHHHHH~~B~~TTSTT~~B~~~S~HHHHHHHHHHHHHHHHTT~EEEE~~S~~~~SSGGGGS~~~~~EEEE~~~TT~HHHHS~~~SSEEEEEEE~~HHHHHHHHH~SSEESEEEEE~~BHHHHHHHHTTS~SSEEEES~SS~~~TTS~B~~EETTEES~BSHHHHHHHTEEEEEEEEE~~EE~EEETTEEE~~SEEEEEE~TTT~~EEEEEEE~~HHHHHHHHHHHHHHTTSGGGG~~HHHHHHHHHHHHHHHHTTHHHHHHHHHHHH~~~HHHHHHTHHHHHHHHHHHHHHHHHH~~EEEEEE~~TTS~~EEEEEEEEE~SEEEEE~~SSSHHHHHHHHHHHHHHTT~EEEEE~~TT~~HHHHHHHHHHHHTT~~TTSEEE~~~~STTSHHHHHHT~TT~SEEEEES~HHHHHHHHHHTGGGT~EEEEE~~~~EEEEE~TTS~HHHHHHHHHHHHHGGGG~STT~EEEEEEEGGGHHHHHHHHHHHHHH~~BS~TTSTT~~B~~~S~HHHHHHHHHHHHHHHHTT~EEEE~~S~~~~SSGGGGS~~~~~EEEE~~~TT~HHHHS~~~SSEEEEEEE~~HHHHHHHHH~SS~~SEEEEE~~BHHHHHHHHTTS~SSEEEESSSS~~~TTS~B~~SGGGEES~BSHHHHHHHTEEEEEEEEE~~EE~EEETTEEE~~SEEEEEE~TTT~~EEEEEEE~~HHHHHHHHHHHHHHHTSHHHH~~HHHHHHHHHHHHHHHHHTHHHHHHHHHHHH~~~HHHHHHTHHHHHHHHHHHHHHHHHH~~EEEEEE~~TTSS~EEEEEEEEE~SEEEEE~~SSSHHHHHHHHHHHHHHTT~EEEEE~~TT~~HHHHHHHHHHHHTT~~TTSEEE~~~~STTSHHHHHHH~TT~SEEEEES~HHHHHHHHHHHGGGT~EEEEE~~~~EEEEE~TTS~HHHHHHHHHHHHHGGGG~STT~EEEEEEEGGGHHHHHHHHHHHHHH~~B~~TTSTT~~B~~~S~HHHHHHHHHHHHHHHHTT~EEEE~~S~~~~SSGGGGS~~~~~EEEE~~~TTSHHHHS~~~SSEEEEEEE~~HHHHHHHHH~SS~~SEEEEE~~BHHHHHHHHTTS~SSEEEESSSS~~~TTS~B~~SGGGEES~BSTHHHHHHTEEEEEEEEE~

S Q L L N Y I D G N F V T S A S S F A N I N P V N G K L I S D V F E A D A K Q V N E A V V A A Q N A L K G P W G K L S V Q D R A A L I H K I A D G I Q A R F E E F V A A E V A D T G R P V H Q A R T L D I P R A I A N F R T F A D L A K T S H T D L F E M S T S D G S G A L N Y T V R K P L G V I G V I S P W N L P L L L F T W K V A P A L A C G N T V V A K P S E E S P S S A T L L A E V M H D A G V P P G V F N L I H G F G K D S A G E F L T Q H P G I S A L T F T G E S K T G S T I M K A V A D G V K E V S F E L G G K N A A V V F A D A D L D A A I E G V L R S S F T N S G Q V C L C S E R V Y V H R S I F D E F V S G L K V E A E R L V V G Y P D Q D G V N M G P L I S H G H R D K V L S Y Y R L A V D E G A T V V T G G G V P K F N D E R D Q G A Y V Q P T I W T G L S D K A R C V T E E I F G P V C H I S P F D D E D E V I N R V N D S N Y G L A C A I W T T N L S R A H R V S R Q I H V G L V W V N T W Y L R D L R T P F G G V K L S G L G R E G G R F S M D F Y S D I A N I C I K I S Q L L N Y I D G N F V T S A S S F A N I N P V N G K L I S D V F E A D A K Q V N E A V V A A Q N A L K G P W G K L S V Q D R A A L I H K I A D G I Q A R F E E F V A A E V A D T G R P V H Q A R T L D I P R A I A N F R T F A D L A K T S H T D L F E M S T S D G S G A L N Y T V R K P L G V I G V I S P W N L P L L L F T W K V A P A L A C G N T V V A K P S E E S P S S A T L L A E V M H D A G V P P G V F N L I H G F G K D S A G E F L T Q H P G I S A L T F T G E S K T G S T I M K A V A D G V K E V S F E L G G K N A A V V F A D A D L D A A I E G V L R S S F T N S G Q V C L C S E R V Y V H R S I F D E F V S G L K V E A E R L V V G Y P D Q D G V N M G P L I S H G H R D K V L S Y Y R L A V D E G A T V V T G G G V P K F N D E R D Q G A Y V Q P T I W T G L S D K A R C V T E E I F G P V C H I S P F D D E D E V I N R V N D S N Y G L A C A I W T T N L S R A H R V S R Q I H V G L V W V N T W Y L R D L R T P F G G V K L S G L G R E G G R F S M D F Y S D I A N I C I K I S Q L L N Y I D G N F V T S A S S F A N I N P V N G K L I S D V F E A D A K Q V N E A V V A A Q N A L K G P W G K L S V Q D R A A L I H K I A D G I Q A R F E E F V A A E V A D T G R P V H Q A R T L D I P R A I A N F R T F A D L A K T S H T D L F E M S T S D G S G A L N Y T V R K P L G V I G V I S P W N L P L L L F T W K V A P A L A C G N T V V A K P S E E S P S S A T L L A E V M H D A G V P P G V F N L I H G F G K D S A G E F L T Q H P G I S A L T F T G E S K T G S T I M K A V A D G V K E V S F E L G G K N A A V V F A D A D L D A A I E G V L R S S F T N S G Q V C L C S E R V Y V H R S I F D E F V S G L K V E A E R L V V G Y P D Q D G V N M G P L I S H G H R D K V L S Y Y R L A V D E G A T V V T G G G V P K F N D E R D Q G A Y V Q P T I W T G L S D K A R C V T E E I F G P V C H I S P F D D E D E V I N R V N D S N Y G L A C A I W T T N L S R A H R V S R Q I H V G L V W V N T W Y L R D L R T P F G G V K L S G L G R E G G R F S M D F Y S D I A N I C I K I S Q L L N Y I D G N F V T S A S S F A N I N P V N G K L I S D V F E A D A K Q V N E A V V A A Q N A L K G P W G K L S V Q D R A A L I H K I A D G I Q A R F E E F V A A E V A D T G R P V H Q A R T L D I P R A I A N F R T F A D L A K T S H T D L F E M S T S D G S G A L N Y T V R K P L G V I G V I S P W N L P L L L F T W K V A P A L A C G N T V V A K P S E E S P S S A T L L A E V M H D A G V P P G V F N L I H G F G K D S A G E F L T Q H P G I S A L T F T G E S K T G S T I M K A V A D G V K E V S F E L G G K N A A V V F A D A D L D A A I E G V L R S S F T N S G Q V C L C S E R V Y V H R S I F D E F V S G L K V E A E R L V V G Y P D Q D G V N M G P L I S H G H R D K V L S Y Y R L A V D E G A T V V T G G G V P K F N D E R D Q G A Y V Q P T I W T G L S D K A R C V T E E I F G P V C H I S P F D D E D E V I N R V N D S N Y G L A C A I W T T N L S R A H R V S R Q I H V G L V W V N T W Y L R D L R T P F G G V K L S G L G R E G G R F S M D F Y S D I A N I C I K I

AH

BS

3SV8

KGSVVIVGRINLSGDTAYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVSTATQTFLATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRAAVSTRGVAKAVAFIPVESLETTMRS

~~~BEEEEEEE~SSSS~EEEE~~~HHHHHHHHHH~B~~~~~~SSEEEEE~SS~EEEEEEETTEEEEEHHHHTT~~B~BTTS~B~~SEEETTTTEEEEE~~TT~~~B~B~~S~~SEEEEE~TT~~EEEEEE~SSSEEEEEEEEEHHHHTT~TT~EEE~TTS~EEEEEEEEEEETTEEEEEEEEEHHHHHHHH~~

K G S V V I V G R I N L S G D T A Y A Q Q T R G E E G C Q E T S Q T G R D K N Q V E G E V Q I V S T A T Q T F L A T S I N G V L W T V Y H G A G T R T I A S P K G P V T Q M Y T N V D K D L V G W Q A P Q G S R S L T P C T C G S S D L Y L V T R H A D V I P V R R R G D S R G S L L S P R P I S Y L K G S S G G P L L C P A G H A V G I F R A A V S T R G V A K A V A F I P V E S L E T T M R S

BS

UNSTRUCTURED

1M2F

MLSQIAICIWVESTAILQDCQRALSADRYQLQVCESGEMLLEYAQTHRDQIDCLILVAANPSFRAVVQQLCFEGVVVPAIVVGDRDSEDPDEPAKEQLYHSAELHLGIHQLEQLPYQVDAALAEFLRLAPVETMA

~~~~EEEEEE~S~HHHHHHHHHHS~~TTEEEEEESSSHHHHHHHTTTTTT~~EEEEETTSSTHHHHHHHHHHHT~~~~EEEE~~~~S~~SS~~~~S~SS~TT~EEE~GGGTT~HHHHHHHHHHHHHHH~S~~~~~

M L S Q I A I C I W V E S T A I L Q D C Q R A L S A D R Y Q L Q V C E S G E M L L E Y A Q T H R D Q I D C L I L V A A N P S F R A V V Q Q L C F E G V V V P A I V V G D R D S E D P D E P A K E Q L Y H S A E L H L G I H Q L E Q L P Y Q V D A A L A E F L R L A P V E T M A

AH

UNSTRUCTURED

1XII

YQPTPEDRFTFGLWTVGWQGRDPFGDATRRALDPVESVQRLAELGAHGVTFHDDDLIPFGSSDSEREEHVKRFRQALDDTGMKVPMATTNLFTHPVFKDGGFTANDRDVRRYALRKTIRNIDLAVELGAETYVAWGGREGAESGGAKDVRDALDRMKEAFDLLGEYVTSQGYDIRFAIEPKPNEPRGDILLPTVGHALAFIERLERPELYGVNPEVGHEQMAGLNFPHGIAQALWAGKLFHIDLNGQNGIKYDQDLRFGAGDLRAAFWLVDLLESAGYSGPRHFDFKPPRTEDFDGVWASAAGCMRNYLILKERAAAFRADPEVQEALRASRLDELARPTAADGLQALLDDRSAFEEFDVDAAAARGMAFERLDQLAMDHLLGAR

~~~~GGG~EEEEHHHHT~~~~BTTB~~SS~~~~HHHHHHHHHHHT~~EEEEEHHHHS~TT~~HHHHHHHHHHHHHHHHHHT~B~~EEE~~~SSSGGGTT~STT~SSHHHHHHHHHHHHHHHHHHHHTT~SEEEE~~TT~EESSSTT~~HHHHHHHHHHHHHHHHHHHHHHT~~~EEEE~~~SSSSSSEESS~SHHHHHHHHTTSSSGGGEEE~~BHHHHHTTT~~HHHHHHHHHHTT~B~~~EE~B~~SSSS~~~B~TTSS~HHHHHHHHHHHHHTT~~S~EEE~~~~~TT~~HHHHHHHHHHHHHHHHHHHHHHHHHHH~HHHHHHHHHTTHHHHTS~S~TT~HHHHHH~GGGTTT~~HHHHHTS~~~HHHHHHHHHHHHHT~~

Y Q P T P E D R F T F G L W T V G W Q G R D P F G D A T R R A L D P V E S V Q R L A E L G A H G V T F H D D D L I P F G S S D S E R E E H V K R F R Q A L D D T G M K V P M A T T N L F T H P V F K D G G F T A N D R D V R R Y A L R K T I R N I D L A V E L G A E T Y V A W G G R E G A E S G G A K D V R D A L D R M K E A F D L L G E Y V T S Q G Y D I R F A I E P K P N E P R G D I L L P T V G H A L A F I E R L E R P E L Y G V N P E V G H E Q M A G L N F P H G I A Q A L W A G K L F H I D L N G Q N G I K Y D Q D L R F G A G D L R A A F W L V D L L E S A G Y S G P R H F D F K P P R T E D F D G V W A S A A G C M R N Y L I L K E R A A A F R A D P E V Q E A L R A S R L D E L A R P T A A D G L Q A L L D D R S A F E E F D V D A A A A R G M A F E R L D Q L A M D H L L G A R

AH

UNSTRUCTURED