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<b>Mass action rate law for first order irreversible reactions</b>
<p>
Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of one reactant.
</p>
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      <Expression>
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      <Expression>
        total/(1+exp(-sigma)^wfunction)
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      </MiriamAnnotation>
      <Expression>
        mu*V
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_482" name="V" order="0" role="product"/>
        <ParameterDescription key="FunctionParameter_483" name="mu" order="1" role="constant"/>
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    </Function>
    <Function key="Function_73" name="Rate Law for Cln3 Synth_1" type="UserDefined" reversible="false">
      <Expression>
        ks_n3*Dn3*V/(Jn3+Dn3*V)
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      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_488" name="Dn3" order="0" role="constant"/>
        <ParameterDescription key="FunctionParameter_489" name="Jn3" order="1" role="constant"/>
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    </Function>
    <Function key="Function_74" name="Rate Law for Bck2 Synth_1" type="UserDefined" reversible="false">
      <Expression>
        V*ks_k2
      </Expression>
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        <ParameterDescription key="FunctionParameter_496" name="V" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_497" name="ks_k2" order="1" role="constant"/>
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      </MiriamAnnotation>
      <Expression>
        gamma*(Sigmoid(WHI5T,sig,kdp_i5+kdp_i5_14*CDC14-kp_i5-kp_i5_n3*CLN3-kp_i5_k2*BCK2-kp_i5_n2*CLN2-kp_i5_b5*CLB5)-WHI5deP)
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      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_516" name="BCK2" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_517" name="CDC14" order="1" role="modifier"/>
        <ParameterDescription key="FunctionParameter_518" name="CLB5" order="2" role="modifier"/>
        <ParameterDescription key="FunctionParameter_519" name="CLN2" order="3" role="modifier"/>
        <ParameterDescription key="FunctionParameter_520" name="CLN3" order="4" role="modifier"/>
        <ParameterDescription key="FunctionParameter_521" name="WHI5T" order="5" role="constant"/>
        <ParameterDescription key="FunctionParameter_522" name="WHI5deP" order="6" role="product"/>
        <ParameterDescription key="FunctionParameter_523" name="gamma" order="7" role="constant"/>
        <ParameterDescription key="FunctionParameter_524" name="kdp_i5" order="8" role="constant"/>
        <ParameterDescription key="FunctionParameter_525" name="kdp_i5_14" order="9" role="constant"/>
        <ParameterDescription key="FunctionParameter_526" name="kp_i5" order="10" role="constant"/>
        <ParameterDescription key="FunctionParameter_527" name="kp_i5_b5" order="11" role="constant"/>
        <ParameterDescription key="FunctionParameter_528" name="kp_i5_k2" order="12" role="constant"/>
        <ParameterDescription key="FunctionParameter_529" name="kp_i5_n2" order="13" role="constant"/>
        <ParameterDescription key="FunctionParameter_530" name="kp_i5_n3" order="14" role="constant"/>
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      <Expression>
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      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_503" name="CLB2" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_500" name="SBFT" order="1" role="constant"/>
        <ParameterDescription key="FunctionParameter_515" name="SBFdeP" order="2" role="product"/>
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        <ParameterDescription key="FunctionParameter_508" name="kdp_bf" order="4" role="constant"/>
        <ParameterDescription key="FunctionParameter_512" name="kp_bf_b2" order="5" role="constant"/>
        <ParameterDescription key="FunctionParameter_514" name="sig" order="6" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
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        ks_n2+ks_n2_bf*SBF
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_502" name="SBF" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_504" name="ks_n2" order="1" role="constant"/>
        <ParameterDescription key="FunctionParameter_507" name="ks_n2_bf" order="2" role="constant"/>
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  </rdf:Description>
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      </MiriamAnnotation>
      <Expression>
        ks_ki+ks_ki_swi5*SWI5A
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_557" name="SWI5A" order="0" role="modifier"/>
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    <Function key="Function_79" name="Rate Law for CKIT Degr_1" type="UserDefined" reversible="false">
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        kd_ki*(CKIT-CKIP)+kd_kip*CKIP
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        <ParameterDescription key="FunctionParameter_564" name="CKIP" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_565" name="CKIT" order="1" role="substrate"/>
        <ParameterDescription key="FunctionParameter_566" name="kd_ki" order="2" role="constant"/>
        <ParameterDescription key="FunctionParameter_567" name="kd_kip" order="3" role="constant"/>
      </ListOfParameterDescriptions>
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      <Expression>
        gammaki*(Sigmoid(CKIT,sig,kp_ki_e*(e_ki_n3*CLN3+e_ki_k2*BCK2+e_ki_n2*CLN2+e_ki_b5*CLB5+e_ki_b2*CLB2)-kdp_ki-kdp_ki_14*CDC14)-CKIP)-kd_kip*CKIP
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_587" name="BCK2" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_588" name="CDC14" order="1" role="modifier"/>
        <ParameterDescription key="FunctionParameter_589" name="CKIP" order="2" role="product"/>
        <ParameterDescription key="FunctionParameter_590" name="CKIT" order="3" role="modifier"/>
        <ParameterDescription key="FunctionParameter_591" name="CLB2" order="4" role="modifier"/>
        <ParameterDescription key="FunctionParameter_592" name="CLB5" order="5" role="modifier"/>
        <ParameterDescription key="FunctionParameter_593" name="CLN2" order="6" role="modifier"/>
        <ParameterDescription key="FunctionParameter_594" name="CLN3" order="7" role="modifier"/>
        <ParameterDescription key="FunctionParameter_595" name="e_ki_b2" order="8" role="constant"/>
        <ParameterDescription key="FunctionParameter_596" name="e_ki_b5" order="9" role="constant"/>
        <ParameterDescription key="FunctionParameter_597" name="e_ki_k2" order="10" role="constant"/>
        <ParameterDescription key="FunctionParameter_598" name="e_ki_n2" order="11" role="constant"/>
        <ParameterDescription key="FunctionParameter_599" name="e_ki_n3" order="12" role="constant"/>
        <ParameterDescription key="FunctionParameter_600" name="gammaki" order="13" role="constant"/>
        <ParameterDescription key="FunctionParameter_601" name="kd_kip" order="14" role="constant"/>
        <ParameterDescription key="FunctionParameter_602" name="kdp_ki" order="15" role="constant"/>
        <ParameterDescription key="FunctionParameter_603" name="kdp_ki_14" order="16" role="constant"/>
        <ParameterDescription key="FunctionParameter_604" name="kp_ki_e" order="17" role="constant"/>
        <ParameterDescription key="FunctionParameter_605" name="sig" order="18" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
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      <Expression>
        ks_b5+ks_b5_bf*SBF
      </Expression>
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        <ParameterDescription key="FunctionParameter_582" name="SBF" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_586" name="ks_b5" order="1" role="constant"/>
        <ParameterDescription key="FunctionParameter_563" name="ks_b5_bf" order="2" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
    <Function key="Function_82" name="Rate Law for Clb5T Degr_1" type="UserDefined" reversible="false">
      <Expression>
        (kd_b5+kd_b5_20*CDC20A+kd_b5_20_i*CDC20A_APC)*CLB5T
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_584" name="CDC20A" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_585" name="CDC20A_APC" order="1" role="modifier"/>
        <ParameterDescription key="FunctionParameter_555" name="CLB5T" order="2" role="substrate"/>
        <ParameterDescription key="FunctionParameter_581" name="kd_b5" order="3" role="constant"/>
        <ParameterDescription key="FunctionParameter_579" name="kd_b5_20" order="4" role="constant"/>
        <ParameterDescription key="FunctionParameter_577" name="kd_b5_20_i" order="5" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
    <Function key="Function_83" name="Rate Law for Clb2T Synth_1" type="UserDefined" reversible="false">
      <Expression>
        (ks_b2+ks_b2_m1*MCM1)*V
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_580" name="MCM1" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_583" name="V" order="1" role="modifier"/>
        <ParameterDescription key="FunctionParameter_630" name="ks_b2" order="2" role="constant"/>
        <ParameterDescription key="FunctionParameter_631" name="ks_b2_m1" order="3" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
    <Function key="Function_84" name="Rate Law for Clb2T Degr_1" type="UserDefined" reversible="false">
      <Expression>
        (kd_b2+kd_b2_20*CDC20A+kd_b2_20_i*CDC20A_APC+kd_b2_h1*CDH1A)*CLB2T
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_647" name="CDC20A" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_646" name="CDC20A_APC" order="1" role="modifier"/>
        <ParameterDescription key="FunctionParameter_645" name="CDH1A" order="2" role="modifier"/>
        <ParameterDescription key="FunctionParameter_644" name="CLB2T" order="3" role="substrate"/>
        <ParameterDescription key="FunctionParameter_643" name="kd_b2" order="4" role="constant"/>
        <ParameterDescription key="FunctionParameter_642" name="kd_b2_20" order="5" role="constant"/>
        <ParameterDescription key="FunctionParameter_641" name="kd_b2_20_i" order="6" role="constant"/>
        <ParameterDescription key="FunctionParameter_640" name="kd_b2_h1" order="7" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
    <Function key="Function_85" name="Rate Law for BUD Synth_1" type="UserDefined" reversible="false">
      <Expression>
        ks_bud_e*(e_bud_n3*CLN3+e_bud_n2*CLN2+e_bud_b5*CLB5+e_bud_b2*CLB2)
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_657" name="CLB2" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_658" name="CLB5" order="1" role="modifier"/>
        <ParameterDescription key="FunctionParameter_659" name="CLN2" order="2" role="modifier"/>
        <ParameterDescription key="FunctionParameter_660" name="CLN3" order="3" role="modifier"/>
        <ParameterDescription key="FunctionParameter_661" name="e_bud_b2" order="4" role="constant"/>
        <ParameterDescription key="FunctionParameter_662" name="e_bud_b5" order="5" role="constant"/>
        <ParameterDescription key="FunctionParameter_663" name="e_bud_n2" order="6" role="constant"/>
        <ParameterDescription key="FunctionParameter_664" name="e_bud_n3" order="7" role="constant"/>
        <ParameterDescription key="FunctionParameter_665" name="ks_bud_e" order="8" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
    <Function key="Function_86" name="Rate Law for ORI Synth_1" type="UserDefined" reversible="false">
      <Expression>
        ks_ori_e*(e_ori_b5*CLB5+e_ori_b2*CLB2)
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_636" name="CLB2" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_656" name="CLB5" order="1" role="modifier"/>
        <ParameterDescription key="FunctionParameter_675" name="e_ori_b2" order="2" role="constant"/>
        <ParameterDescription key="FunctionParameter_676" name="e_ori_b5" order="3" role="constant"/>
        <ParameterDescription key="FunctionParameter_677" name="ks_ori_e" order="4" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
    <Function key="Function_87" name="Rate Law for SPN Synth_1" type="UserDefined" reversible="false">
      <Expression>
        ks_spn*Heav(CLB2-Jspn)
      </Expression>
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        <ParameterDescription key="FunctionParameter_683" name="CLB2" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_684" name="Jspn" order="1" role="constant"/>
        <ParameterDescription key="FunctionParameter_685" name="ks_spn" order="2" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
    <Function key="Function_88" name="Rate Law for SWI5T Synth_1" type="UserDefined" reversible="false">
      <Expression>
        ks_swi5+ks_swi5_m1*MCM1
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_691" name="MCM1" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_692" name="ks_swi5" order="1" role="constant"/>
        <ParameterDescription key="FunctionParameter_693" name="ks_swi5_m1" order="2" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
    <Function key="Function_89" name="Rate Law for CDC20T Synth_1" type="UserDefined" reversible="false">
      <Expression>
        ks_20+ks_20_m1*MCM1
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_699" name="MCM1" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_700" name="ks_20" order="1" role="constant"/>
        <ParameterDescription key="FunctionParameter_701" name="ks_20_m1" order="2" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
    <Function key="Function_90" name="Rate Law for CDC20A_APCP Synth_1" type="UserDefined" reversible="true">
      <Expression>
        gamma*(Sigmoid(CDC20A_APCP_T,sig,ka_20-ki_20_ori*Heav(ORI-1)*(1-Heav(SPN-1)))-CDC20A)-kd_20*CDC20A
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_721" name="CDC20A" order="0" role="product"/>
        <ParameterDescription key="FunctionParameter_720" name="CDC20A_APCP_T" order="1" role="modifier"/>
        <ParameterDescription key="FunctionParameter_719" name="ORI" order="2" role="modifier"/>
        <ParameterDescription key="FunctionParameter_718" name="SPN" order="3" role="modifier"/>
        <ParameterDescription key="FunctionParameter_717" name="gamma" order="4" role="constant"/>
        <ParameterDescription key="FunctionParameter_716" name="ka_20" order="5" role="constant"/>
        <ParameterDescription key="FunctionParameter_715" name="kd_20" order="6" role="constant"/>
        <ParameterDescription key="FunctionParameter_714" name="ki_20_ori" order="7" role="constant"/>
        <ParameterDescription key="FunctionParameter_713" name="sig" order="8" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
    <Function key="Function_91" name="Rate Law for APCP Synth_1" type="UserDefined" reversible="true">
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      <Expression>
        gammacp*(Sigmoid(APCPT,sig,ka_cp_b2*CLB2-ki_cp)-APCP)
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_705" name="APCP" order="0" role="product"/>
        <ParameterDescription key="FunctionParameter_711" name="APCPT" order="1" role="constant"/>
        <ParameterDescription key="FunctionParameter_731" name="CLB2" order="2" role="modifier"/>
        <ParameterDescription key="FunctionParameter_732" name="gammacp" order="3" role="constant"/>
        <ParameterDescription key="FunctionParameter_733" name="ka_cp_b2" order="4" role="constant"/>
        <ParameterDescription key="FunctionParameter_734" name="ki_cp" order="5" role="constant"/>
        <ParameterDescription key="FunctionParameter_735" name="sig" order="6" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
    <Function key="Function_92" name="Rate Law for CDH1A Synth_1" type="UserDefined" reversible="true">
      <Expression>
        gamma*(Sigmoid(CDH1T,sig,ka_h1+ka_h1_14*CDC14-ki_h1-ki_h1_e*(e_h1_n3*CLN3+e_h1_n2*CLN2+e_h1_b5*CLB5+e_h1_b2*CLB2))-CDH1A)
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_753" name="CDC14" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_754" name="CDH1A" order="1" role="product"/>
        <ParameterDescription key="FunctionParameter_755" name="CDH1T" order="2" role="constant"/>
        <ParameterDescription key="FunctionParameter_756" name="CLB2" order="3" role="modifier"/>
        <ParameterDescription key="FunctionParameter_757" name="CLB5" order="4" role="modifier"/>
        <ParameterDescription key="FunctionParameter_758" name="CLN2" order="5" role="modifier"/>
        <ParameterDescription key="FunctionParameter_759" name="CLN3" order="6" role="modifier"/>
        <ParameterDescription key="FunctionParameter_760" name="e_h1_b2" order="7" role="constant"/>
        <ParameterDescription key="FunctionParameter_761" name="e_h1_b5" order="8" role="constant"/>
        <ParameterDescription key="FunctionParameter_762" name="e_h1_n2" order="9" role="constant"/>
        <ParameterDescription key="FunctionParameter_763" name="e_h1_n3" order="10" role="constant"/>
        <ParameterDescription key="FunctionParameter_764" name="gamma" order="11" role="constant"/>
        <ParameterDescription key="FunctionParameter_765" name="ka_h1" order="12" role="constant"/>
        <ParameterDescription key="FunctionParameter_766" name="ka_h1_14" order="13" role="constant"/>
        <ParameterDescription key="FunctionParameter_767" name="ki_h1" order="14" role="constant"/>
        <ParameterDescription key="FunctionParameter_768" name="ki_h1_e" order="15" role="constant"/>
        <ParameterDescription key="FunctionParameter_769" name="sig" order="16" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
    <Function key="Function_93" name="Rate Law for NET1deP Synth_1" type="UserDefined" reversible="true">
      <Expression>
        gamma*(Sigmoid(NET1T,signet,kdp_net+kdp_net_14*CDC14+kdp_net_px*PPX-kp_net-kp_net_b2*CLB2-kp_net_en*MEN-kp_net_15*CDC15)-NET1deP)
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_708" name="CDC14" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_787" name="CDC15" order="1" role="modifier"/>
        <ParameterDescription key="FunctionParameter_788" name="CLB2" order="2" role="modifier"/>
        <ParameterDescription key="FunctionParameter_789" name="MEN" order="3" role="modifier"/>
        <ParameterDescription key="FunctionParameter_790" name="NET1T" order="4" role="constant"/>
        <ParameterDescription key="FunctionParameter_791" name="NET1deP" order="5" role="product"/>
        <ParameterDescription key="FunctionParameter_792" name="PPX" order="6" role="modifier"/>
        <ParameterDescription key="FunctionParameter_793" name="gamma" order="7" role="constant"/>
        <ParameterDescription key="FunctionParameter_794" name="kdp_net" order="8" role="constant"/>
        <ParameterDescription key="FunctionParameter_795" name="kdp_net_14" order="9" role="constant"/>
        <ParameterDescription key="FunctionParameter_796" name="kdp_net_px" order="10" role="constant"/>
        <ParameterDescription key="FunctionParameter_797" name="kp_net" order="11" role="constant"/>
        <ParameterDescription key="FunctionParameter_798" name="kp_net_15" order="12" role="constant"/>
        <ParameterDescription key="FunctionParameter_799" name="kp_net_b2" order="13" role="constant"/>
        <ParameterDescription key="FunctionParameter_800" name="kp_net_en" order="14" role="constant"/>
        <ParameterDescription key="FunctionParameter_801" name="signet" order="15" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
    <Function key="Function_94" name="Rate Law for PPX Synth_1" type="UserDefined" reversible="true">
      <Expression>
        gamma*(Sigmoid(PPXT,sig,ka_px-ki_px-ki_px_p1*ESP1)-PPX)
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_707" name="ESP1" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_746" name="PPX" order="1" role="product"/>
        <ParameterDescription key="FunctionParameter_752" name="PPXT" order="2" role="constant"/>
        <ParameterDescription key="FunctionParameter_743" name="gamma" order="3" role="constant"/>
        <ParameterDescription key="FunctionParameter_749" name="ka_px" order="4" role="constant"/>
        <ParameterDescription key="FunctionParameter_745" name="ki_px" order="5" role="constant"/>
        <ParameterDescription key="FunctionParameter_710" name="ki_px_p1" order="6" role="constant"/>
        <ParameterDescription key="FunctionParameter_712" name="sig" order="7" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
    <Function key="Function_95" name="Rate Law for PDS1T Degr_1" type="UserDefined" reversible="false">
      <Expression>
        (kd_pds+ks_pds_20*CDC20A+kd_pds_20_i*CDC20A_APC)*PDS1T
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_830" name="CDC20A" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_829" name="CDC20A_APC" order="1" role="modifier"/>
        <ParameterDescription key="FunctionParameter_828" name="PDS1T" order="2" role="substrate"/>
        <ParameterDescription key="FunctionParameter_827" name="kd_pds" order="3" role="constant"/>
        <ParameterDescription key="FunctionParameter_826" name="kd_pds_20_i" order="4" role="constant"/>
        <ParameterDescription key="FunctionParameter_706" name="ks_pds_20" order="5" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
    <Function key="Function_96" name="Rate Law for CDC15 Synth_1" type="UserDefined" reversible="true">
      <Expression>
        gamma*(Sigmoid(CDC15T,sig,ka_15+ka_15_14*CDC14-ki_15-ki_15_b2*CLB2)-CDC15)
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_841" name="CDC14" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_842" name="CDC15" order="1" role="product"/>
        <ParameterDescription key="FunctionParameter_843" name="CDC15T" order="2" role="constant"/>
        <ParameterDescription key="FunctionParameter_844" name="CLB2" order="3" role="modifier"/>
        <ParameterDescription key="FunctionParameter_845" name="gamma" order="4" role="constant"/>
        <ParameterDescription key="FunctionParameter_846" name="ka_15" order="5" role="constant"/>
        <ParameterDescription key="FunctionParameter_847" name="ka_15_14" order="6" role="constant"/>
        <ParameterDescription key="FunctionParameter_848" name="ki_15" order="7" role="constant"/>
        <ParameterDescription key="FunctionParameter_849" name="ki_15_b2" order="8" role="constant"/>
        <ParameterDescription key="FunctionParameter_850" name="sig" order="9" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
    <Function key="Function_97" name="Rate Law for TEM1 Synth_1" type="UserDefined" reversible="true">
      <MiriamAnnotation>
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  <rdf:Description rdf:about="#Function_97">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-04-09T15:10:39Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
      </MiriamAnnotation>
      <Expression>
        gammatem*(Sigmoid(TEM1T,sig,ka_tem+ka_tem_lo*POLOA+ka_tem_p1*ESP1-ki_tem-ki_tem_px*PPX)-TEM1)
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_863" name="ESP1" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_864" name="POLOA" order="1" role="modifier"/>
        <ParameterDescription key="FunctionParameter_865" name="PPX" order="2" role="modifier"/>
        <ParameterDescription key="FunctionParameter_866" name="TEM1" order="3" role="product"/>
        <ParameterDescription key="FunctionParameter_867" name="TEM1T" order="4" role="constant"/>
        <ParameterDescription key="FunctionParameter_868" name="gammatem" order="5" role="constant"/>
        <ParameterDescription key="FunctionParameter_869" name="ka_tem" order="6" role="constant"/>
        <ParameterDescription key="FunctionParameter_870" name="ka_tem_lo" order="7" role="constant"/>
        <ParameterDescription key="FunctionParameter_871" name="ka_tem_p1" order="8" role="constant"/>
        <ParameterDescription key="FunctionParameter_872" name="ki_tem" order="9" role="constant"/>
        <ParameterDescription key="FunctionParameter_873" name="ki_tem_px" order="10" role="constant"/>
        <ParameterDescription key="FunctionParameter_874" name="sig" order="11" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
    <Function key="Function_98" name="Rate Law for POLOT Synth_1" type="UserDefined" reversible="false">
      <Expression>
        ks_lo+ks_lo_m1*MCM1
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_839" name="MCM1" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_698" name="ks_lo" order="1" role="constant"/>
        <ParameterDescription key="FunctionParameter_747" name="ks_lo_m1" order="2" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
    <Function key="Function_99" name="Rate Law for POLOT Degr_1" type="UserDefined" reversible="false">
      <Expression>
        (kd_lo+kd_lo_h1*CDH1A)*POLOT
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_748" name="CDH1A" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_709" name="POLOT" order="1" role="substrate"/>
        <ParameterDescription key="FunctionParameter_887" name="kd_lo" order="2" role="constant"/>
        <ParameterDescription key="FunctionParameter_888" name="kd_lo_h1" order="3" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
    <Function key="Function_100" name="Rate Law for POLOA Synth_1" type="UserDefined" reversible="true">
      <Expression>
        gamma*(Sigmoid(POLOT,sig,ka_lo+ka_lo_b2*CLB2-ki_lo)-POLOA)-(kd_lo+kd_lo_h1*CDH1A)*POLOA
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_900" name="CDH1A" order="0" role="modifier"/>
        <ParameterDescription key="FunctionParameter_901" name="CLB2" order="1" role="modifier"/>
        <ParameterDescription key="FunctionParameter_902" name="POLOA" order="2" role="product"/>
        <ParameterDescription key="FunctionParameter_903" name="POLOT" order="3" role="modifier"/>
        <ParameterDescription key="FunctionParameter_904" name="gamma" order="4" role="constant"/>
        <ParameterDescription key="FunctionParameter_905" name="ka_lo" order="5" role="constant"/>
        <ParameterDescription key="FunctionParameter_906" name="ka_lo_b2" order="6" role="constant"/>
        <ParameterDescription key="FunctionParameter_907" name="kd_lo" order="7" role="constant"/>
        <ParameterDescription key="FunctionParameter_908" name="kd_lo_h1" order="8" role="constant"/>
        <ParameterDescription key="FunctionParameter_909" name="ki_lo" order="9" role="constant"/>
        <ParameterDescription key="FunctionParameter_910" name="sig" order="10" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
    <Function key="Function_101" name="Rate Law for CDC20A_APC Synth_1" type="UserDefined" reversible="true">
      <Expression>
        gamma*(Sigmoid(CDC20A_APC_T,sig,ka_20-ki_20_ori*Heav(ORI-1)*(1-Heav(SPN-1)))-CDC20A_APC)-kd_20*CDC20A_APC
      </Expression>
      <ListOfParameterDescriptions>
        <ParameterDescription key="FunctionParameter_894" name="CDC20A_APC" order="0" role="product"/>
        <ParameterDescription key="FunctionParameter_899" name="CDC20A_APC_T" order="1" role="modifier"/>
        <ParameterDescription key="FunctionParameter_922" name="ORI" order="2" role="modifier"/>
        <ParameterDescription key="FunctionParameter_923" name="SPN" order="3" role="modifier"/>
        <ParameterDescription key="FunctionParameter_924" name="gamma" order="4" role="constant"/>
        <ParameterDescription key="FunctionParameter_925" name="ka_20" order="5" role="constant"/>
        <ParameterDescription key="FunctionParameter_926" name="kd_20" order="6" role="constant"/>
        <ParameterDescription key="FunctionParameter_927" name="ki_20_ori" order="7" role="constant"/>
        <ParameterDescription key="FunctionParameter_928" name="sig" order="8" role="constant"/>
      </ListOfParameterDescriptions>
    </Function>
  </ListOfFunctions>
  <Model key="Model_1" name="Yeast Cell Cycle_1_1" simulationType="time" timeUnit="min" volumeUnit="l" areaUnit="m²" lengthUnit="m" quantityUnit="mol" type="deterministic" avogadroConstant="6.0221408570000002e+23">
    <MiriamAnnotation>
<rdf:RDF
   xmlns:dcterms="http://purl.org/dc/terms/"
   xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
   xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#">
  <rdf:Description rdf:about="#Model_1">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T09:04:54Z</dcterms:W3CDTF>
      </rdf:Description>
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    <dcterms:creator>
      <rdf:Bag>
        <rdf:li>
          <rdf:Description>
            <vCard:N>
              <rdf:Description>
                <vCard:Family>Mitra</vCard:Family>
                <vCard:Given>Eshan</vCard:Given>
              </rdf:Description>
            </vCard:N>
            <vCard:ORG>
              <rdf:Description>
                <vCard:Orgname>Los Alamos National Lab</vCard:Orgname>
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            </vCard:ORG>
          </rdf:Description>
        </rdf:li>
      </rdf:Bag>
    </dcterms:creator>
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      </rdf:Description>
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  </rdf:Description>
</rdf:RDF>

    </MiriamAnnotation>
    <Comment>
      <body xmlns="http://www.w3.org/1999/xhtml">
    <pre>Model of the yeast cell cycle originally described in Oguz et al (2013) "Optimization and model reduction in the high dimensional parameter space of a budding yeast cell cycle model" BMC Syst. Biol.
Adapted to SBML format and used as an example problem in Mitra et al (2018) "Using both qualitative and quantitative data to imporve parameter identification for systems biology models".</pre>
  </body>
    </Comment>
    <ListOfCompartments>
      <Compartment key="Compartment_1" name="cell" simulationType="fixed" dimensionality="3">
      </Compartment>
    </ListOfCompartments>
    <ListOfMetabolites>
      <Metabolite key="Metabolite_81" name="V" simulationType="reactions" compartment="Compartment_1">
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  <rdf:Description rdf:about="#Metabolite_81">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T09:10:10Z</dcterms:W3CDTF>
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        </MiriamAnnotation>
      </Metabolite>
      <Metabolite key="Metabolite_80" name="BCK2" simulationType="reactions" compartment="Compartment_1">
        <MiriamAnnotation>
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  <rdf:Description rdf:about="#Metabolite_80">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T09:13:02Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
      </Metabolite>
      <Metabolite key="Metabolite_79" name="CLN3" simulationType="reactions" compartment="Compartment_1">
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  <rdf:Description rdf:about="#Metabolite_79">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T10:04:23Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
      </Metabolite>
      <Metabolite key="Metabolite_78" name="WHI5deP" simulationType="reactions" compartment="Compartment_1">
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  <rdf:Description rdf:about="#Metabolite_78">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T10:26:53Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
      </Metabolite>
      <Metabolite key="Metabolite_77" name="SBFdeP" simulationType="reactions" compartment="Compartment_1">
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        <dcterms:W3CDTF>2018-01-06T10:26:52Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
      </Metabolite>
      <Metabolite key="Metabolite_76" name="CLN2" simulationType="reactions" compartment="Compartment_1">
        <MiriamAnnotation>
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  <rdf:Description rdf:about="#Metabolite_76">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T10:18:34Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
      </Metabolite>
      <Metabolite key="Metabolite_75" name="CKIT" simulationType="reactions" compartment="Compartment_1">
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        </MiriamAnnotation>
      </Metabolite>
      <Metabolite key="Metabolite_74" name="CKIP" simulationType="reactions" compartment="Compartment_1">
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    <dcterms:created>
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    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
      </Metabolite>
      <Metabolite key="Metabolite_73" name="CLB5T" simulationType="reactions" compartment="Compartment_1">
        <MiriamAnnotation>
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  <rdf:Description rdf:about="#Metabolite_73">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T10:17:21Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
      </Metabolite>
      <Metabolite key="Metabolite_72" name="CLB2T" simulationType="reactions" compartment="Compartment_1">
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    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T10:26:49Z</dcterms:W3CDTF>
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    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
      </Metabolite>
      <Metabolite key="Metabolite_71" name="BUD" simulationType="reactions" compartment="Compartment_1">
        <MiriamAnnotation>
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  <rdf:Description rdf:about="#Metabolite_71">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T10:26:52Z</dcterms:W3CDTF>
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    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
      </Metabolite>
      <Metabolite key="Metabolite_70" name="ORI" simulationType="reactions" compartment="Compartment_1">
        <MiriamAnnotation>
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    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
      </Metabolite>
      <Metabolite key="Metabolite_69" name="SPN" simulationType="reactions" compartment="Compartment_1">
        <MiriamAnnotation>
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    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
      </Metabolite>
      <Metabolite key="Metabolite_68" name="SWI5T" simulationType="reactions" compartment="Compartment_1">
        <MiriamAnnotation>
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    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T10:17:13Z</dcterms:W3CDTF>
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    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
      </Metabolite>
      <Metabolite key="Metabolite_67" name="CDC20T" simulationType="reactions" compartment="Compartment_1">
        <MiriamAnnotation>
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        </MiriamAnnotation>
      </Metabolite>
      <Metabolite key="Metabolite_66" name="CDC20A_APCP" simulationType="reactions" compartment="Compartment_1">
        <MiriamAnnotation>
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      </Metabolite>
      <Metabolite key="Metabolite_65" name="APCP" simulationType="reactions" compartment="Compartment_1">
        <MiriamAnnotation>
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          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[V],Reference=Concentration>*&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_k2],Reference=Value>-&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_k2],Reference=Value>*&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[BCK2],Reference=Concentration>
        </Expression>
      </Metabolite>
      <Metabolite key="Metabolite_88" name="dCLN2" simulationType="assignment" compartment="Compartment_1">
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          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_ki],Reference=Value>+&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_ki_swi5],Reference=Value>*&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[SWI5A],Reference=Concentration>-(&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_ki],Reference=Value>*(&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CKIT],Reference=Concentration>-&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CKIP],Reference=Concentration>)+&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_kip],Reference=Value>*&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CKIP],Reference=Concentration>)
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      <Metabolite key="Metabolite_90" name="dCLB5T" simulationType="assignment" compartment="Compartment_1">
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</rdf:RDF>
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          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_b5],Reference=Value>+&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_b5_bf],Reference=Value>*&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[SBF],Reference=Concentration>-(&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_b5],Reference=Value>+&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_b5_20],Reference=Value>*&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CDC20A_APCP],Reference=Concentration>+&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_b5_20_i],Reference=Value>*&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CDC20A_APC],Reference=Concentration>)*&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CLB5T],Reference=Concentration>
        </Expression>
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      <Metabolite key="Metabolite_91" name="dCLB2T" simulationType="assignment" compartment="Compartment_1">
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      <Metabolite key="Metabolite_92" name="dSWI5T" simulationType="assignment" compartment="Compartment_1">
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  <rdf:Description rdf:about="#Metabolite_92">
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      <rdf:Description>
        <dcterms:W3CDTF>2018-04-17T09:10:28Z</dcterms:W3CDTF>
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        <Expression>
          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_swi5],Reference=Value>+&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_swi5_m1],Reference=Value>*&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[MCM1],Reference=Concentration>-&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_swi5],Reference=Value>*&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[SWI5T],Reference=Concentration>
        </Expression>
      </Metabolite>
      <Metabolite key="Metabolite_93" name="dCDC20T" simulationType="assignment" compartment="Compartment_1">
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  <rdf:Description rdf:about="#Metabolite_93">
    <dcterms:created>
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        <dcterms:W3CDTF>2018-04-17T09:13:02Z</dcterms:W3CDTF>
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        </MiriamAnnotation>
        <Expression>
          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_20],Reference=Value>+&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_20_m1],Reference=Value>*&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[MCM1],Reference=Concentration>-&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_20],Reference=Value>*&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CDC20T],Reference=Concentration>
        </Expression>
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      <Metabolite key="Metabolite_94" name="dPDS1T" simulationType="assignment" compartment="Compartment_1">
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  <rdf:Description rdf:about="#Metabolite_94">
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        <dcterms:W3CDTF>2018-04-17T09:14:29Z</dcterms:W3CDTF>
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        <Expression>
          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_pds],Reference=Value>-(&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_pds],Reference=Value>+&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_pds_20],Reference=Value>*&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CDC20A_APCP],Reference=Concentration>+&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_pds_20_i],Reference=Value>*&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CDC20A_APC],Reference=Concentration>)*&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[PDS1T],Reference=Concentration>
        </Expression>
      </Metabolite>
      <Metabolite key="Metabolite_95" name="dPOLOT" simulationType="assignment" compartment="Compartment_1">
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        <dcterms:W3CDTF>2018-04-17T09:16:54Z</dcterms:W3CDTF>
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</rdf:RDF>
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        <Expression>
          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_lo],Reference=Value>+&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_lo_m1],Reference=Value>*&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[MCM1],Reference=Concentration>-(&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_lo],Reference=Value>+&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_lo_h1],Reference=Value>*&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CDH1A],Reference=Concentration>)*&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[POLOT],Reference=Concentration>
        </Expression>
      </Metabolite>
      <Metabolite key="Metabolite_96" name="CLN3_peaks" simulationType="reactions" compartment="Compartment_1">
      </Metabolite>
      <Metabolite key="Metabolite_97" name="BCK2_peaks" simulationType="reactions" compartment="Compartment_1">
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      <Metabolite key="Metabolite_98" name="CLN2_peaks" simulationType="reactions" compartment="Compartment_1">
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      <Metabolite key="Metabolite_99" name="CKIT_peaks" simulationType="reactions" compartment="Compartment_1">
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      <Metabolite key="Metabolite_100" name="CLB5T_peaks" simulationType="reactions" compartment="Compartment_1">
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      <Metabolite key="Metabolite_101" name="CLB2T_peaks" simulationType="reactions" compartment="Compartment_1">
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      <Metabolite key="Metabolite_102" name="SWI5T_peaks" simulationType="reactions" compartment="Compartment_1">
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      <Metabolite key="Metabolite_103" name="CDC20T_peaks" simulationType="reactions" compartment="Compartment_1">
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      <Metabolite key="Metabolite_104" name="PDS1T_peaks" simulationType="reactions" compartment="Compartment_1">
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      <Metabolite key="Metabolite_105" name="POLOT_peaks" simulationType="reactions" compartment="Compartment_1">
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      <Metabolite key="Metabolite_106" name="OffsetTime" simulationType="assignment" compartment="Compartment_1">
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   xmlns:dcterms="http://purl.org/dc/terms/"
   xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
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        <dcterms:W3CDTF>2018-04-17T10:33:29Z</dcterms:W3CDTF>
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        </MiriamAnnotation>
        <Expression>
          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Reference=Time>-&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[phi_28],Reference=Value>
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      <Metabolite key="Metabolite_107" name="VDiv1" simulationType="reactions" compartment="Compartment_1">
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      <Metabolite key="Metabolite_108" name="VDiv2" simulationType="reactions" compartment="Compartment_1">
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      <Metabolite key="Metabolite_109" name="VDiv3" simulationType="reactions" compartment="Compartment_1">
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      <Metabolite key="Metabolite_110" name="DIff1" simulationType="assignment" compartment="Compartment_1">
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        <dcterms:W3CDTF>2018-04-17T10:58:30Z</dcterms:W3CDTF>
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          abs(&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[VDiv2],Reference=Concentration>-&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[VDiv1],Reference=Concentration>)
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      <Metabolite key="Metabolite_39" name="OK_LICENSE" simulationType="reactions" compartment="Compartment_1">
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        </MiriamAnnotation>
        <ListOfSubstrates>
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        <ListOfConstants>
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        <ListOfProducts>
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        </ListOfProducts>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_81" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3447" name="ks_k2" value="0.0553"/>
        </ListOfConstants>
        <KineticLaw function="Function_74" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_496">
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        <ListOfSubstrates>
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        <ListOfConstants>
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        <ListOfConstants>
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            <CallParameter functionParameter="FunctionParameter_522">
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            <CallParameter functionParameter="FunctionParameter_524">
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            <CallParameter functionParameter="FunctionParameter_525">
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            <CallParameter functionParameter="FunctionParameter_526">
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            <CallParameter functionParameter="FunctionParameter_527">
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            <CallParameter functionParameter="FunctionParameter_528">
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            <CallParameter functionParameter="FunctionParameter_529">
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            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_530">
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            <CallParameter functionParameter="FunctionParameter_531">
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          </ListOfCallParameters>
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        <ListOfModifiers>
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        <ListOfConstants>
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            <CallParameter functionParameter="FunctionParameter_515">
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            <CallParameter functionParameter="FunctionParameter_508">
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            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_512">
              <SourceParameter reference="ModelValue_231"/>
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            <CallParameter functionParameter="FunctionParameter_514">
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        <ListOfModifiers>
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        <ListOfConstants>
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        </ListOfConstants>
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            <CallParameter functionParameter="FunctionParameter_504">
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            <CallParameter functionParameter="FunctionParameter_507">
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          </ListOfCallParameters>
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        </MiriamAnnotation>
        <ListOfSubstrates>
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        <ListOfConstants>
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        <KineticLaw function="Function_13" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
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            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_68" name="CKIT Synth" reversible="false" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_68">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T13:35:10Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfProducts>
          <Product metabolite="Metabolite_75" stoichiometry="1"/>
        </ListOfProducts>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_47" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3415" name="ks_ki" value="0.00663"/>
          <Constant key="Parameter_3414" name="ks_ki_swi5" value="0.089"/>
        </ListOfConstants>
        <KineticLaw function="Function_78" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_557">
              <SourceParameter reference="Metabolite_47"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_558">
              <SourceParameter reference="ModelValue_227"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_559">
              <SourceParameter reference="ModelValue_226"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_67" name="CKIT Degr" reversible="false" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_67">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T13:42:23Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfSubstrates>
          <Substrate metabolite="Metabolite_75" stoichiometry="1"/>
        </ListOfSubstrates>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_74" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3413" name="kd_ki" value="0.0524"/>
          <Constant key="Parameter_3412" name="kd_kip" value="0.899"/>
        </ListOfConstants>
        <KineticLaw function="Function_79" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_564">
              <SourceParameter reference="Metabolite_74"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_565">
              <SourceParameter reference="Metabolite_75"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_566">
              <SourceParameter reference="ModelValue_225"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_567">
              <SourceParameter reference="ModelValue_224"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_66" name="CKIP Synth" reversible="true" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_66">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T13:44:52Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfProducts>
          <Product metabolite="Metabolite_74" stoichiometry="1"/>
        </ListOfProducts>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_75" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_79" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_80" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_76" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_54" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_53" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_51" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3411" name="e_ki_b2" value="3.12"/>
          <Constant key="Parameter_3410" name="e_ki_b5" value="2.39"/>
          <Constant key="Parameter_3409" name="e_ki_k2" value="0.397"/>
          <Constant key="Parameter_3408" name="e_ki_n2" value="19.5"/>
          <Constant key="Parameter_3407" name="e_ki_n3" value="1.05"/>
          <Constant key="Parameter_3406" name="gammaki" value="12.9"/>
          <Constant key="Parameter_3405" name="kd_kip" value="0.899"/>
          <Constant key="Parameter_3404" name="kdp_ki" value="0.836"/>
          <Constant key="Parameter_3403" name="kdp_ki_14" value="1.11"/>
          <Constant key="Parameter_3402" name="kp_ki_e" value="0.65"/>
          <Constant key="Parameter_3401" name="sig" value="9.63"/>
        </ListOfConstants>
        <KineticLaw function="Function_80" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_587">
              <SourceParameter reference="Metabolite_80"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_588">
              <SourceParameter reference="Metabolite_51"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_589">
              <SourceParameter reference="Metabolite_74"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_590">
              <SourceParameter reference="Metabolite_75"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_591">
              <SourceParameter reference="Metabolite_53"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_592">
              <SourceParameter reference="Metabolite_54"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_593">
              <SourceParameter reference="Metabolite_76"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_594">
              <SourceParameter reference="Metabolite_79"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_595">
              <SourceParameter reference="ModelValue_218"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_596">
              <SourceParameter reference="ModelValue_219"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_597">
              <SourceParameter reference="ModelValue_221"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_598">
              <SourceParameter reference="ModelValue_220"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_599">
              <SourceParameter reference="ModelValue_222"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_600">
              <SourceParameter reference="ModelValue_246"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_601">
              <SourceParameter reference="ModelValue_224"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_602">
              <SourceParameter reference="ModelValue_217"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_603">
              <SourceParameter reference="ModelValue_216"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_604">
              <SourceParameter reference="ModelValue_223"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_605">
              <SourceParameter reference="ModelValue_243"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_65" name="Clb5T Synth" reversible="false" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_65">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T13:50:59Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfProducts>
          <Product metabolite="Metabolite_73" stoichiometry="1"/>
        </ListOfProducts>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_52" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3400" name="ks_b5" value="0.000538"/>
          <Constant key="Parameter_3399" name="ks_b5_bf" value="0.0178"/>
        </ListOfConstants>
        <KineticLaw function="Function_81" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_582">
              <SourceParameter reference="Metabolite_52"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_586">
              <SourceParameter reference="ModelValue_215"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_563">
              <SourceParameter reference="ModelValue_214"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_64" name="Clb5T Degr" reversible="false" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_64">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T13:52:13Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfSubstrates>
          <Substrate metabolite="Metabolite_73" stoichiometry="1"/>
        </ListOfSubstrates>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_66" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_56" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3398" name="kd_b5" value="0.0556"/>
          <Constant key="Parameter_3397" name="kd_b5_20" value="0.0445"/>
          <Constant key="Parameter_3396" name="kd_b5_20_i" value="0.00498"/>
        </ListOfConstants>
        <KineticLaw function="Function_82" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_584">
              <SourceParameter reference="Metabolite_66"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_585">
              <SourceParameter reference="Metabolite_56"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_555">
              <SourceParameter reference="Metabolite_73"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_581">
              <SourceParameter reference="ModelValue_213"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_579">
              <SourceParameter reference="ModelValue_212"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_577">
              <SourceParameter reference="ModelValue_182"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_63" name="Clb2T Synth" reversible="false" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_63">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:00:34Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfProducts>
          <Product metabolite="Metabolite_72" stoichiometry="1"/>
        </ListOfProducts>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_48" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_81" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3395" name="ks_b2" value="0.00762"/>
          <Constant key="Parameter_3394" name="ks_b2_m1" value="0.031"/>
        </ListOfConstants>
        <KineticLaw function="Function_83" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_580">
              <SourceParameter reference="Metabolite_48"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_583">
              <SourceParameter reference="Metabolite_81"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_630">
              <SourceParameter reference="ModelValue_211"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_631">
              <SourceParameter reference="ModelValue_210"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_62" name="Clb2T Degr" reversible="false" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_62">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:01:37Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfSubstrates>
          <Substrate metabolite="Metabolite_72" stoichiometry="1"/>
        </ListOfSubstrates>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_66" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_56" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_64" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3393" name="kd_b2" value="0.00298"/>
          <Constant key="Parameter_3392" name="kd_b2_20" value="0.136"/>
          <Constant key="Parameter_3391" name="kd_b2_20_i" value="0.0374"/>
          <Constant key="Parameter_3390" name="kd_b2_h1" value="0.662"/>
        </ListOfConstants>
        <KineticLaw function="Function_84" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_647">
              <SourceParameter reference="Metabolite_66"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_646">
              <SourceParameter reference="Metabolite_56"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_645">
              <SourceParameter reference="Metabolite_64"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_644">
              <SourceParameter reference="Metabolite_72"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_643">
              <SourceParameter reference="ModelValue_209"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_642">
              <SourceParameter reference="ModelValue_208"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_641">
              <SourceParameter reference="ModelValue_181"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_640">
              <SourceParameter reference="ModelValue_207"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_61" name="BUD Synth" reversible="false" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_61">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:05:26Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfProducts>
          <Product metabolite="Metabolite_71" stoichiometry="1"/>
        </ListOfProducts>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_79" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_76" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_54" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_53" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3389" name="e_bud_b2" value="1.89"/>
          <Constant key="Parameter_3388" name="e_bud_b5" value="3"/>
          <Constant key="Parameter_3387" name="e_bud_n2" value="1.12"/>
          <Constant key="Parameter_3386" name="e_bud_n3" value="0.0078"/>
          <Constant key="Parameter_3385" name="ks_bud_e" value="0.287"/>
        </ListOfConstants>
        <KineticLaw function="Function_85" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_657">
              <SourceParameter reference="Metabolite_53"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_658">
              <SourceParameter reference="Metabolite_54"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_659">
              <SourceParameter reference="Metabolite_76"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_660">
              <SourceParameter reference="Metabolite_79"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_661">
              <SourceParameter reference="ModelValue_202"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_662">
              <SourceParameter reference="ModelValue_203"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_663">
              <SourceParameter reference="ModelValue_204"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_664">
              <SourceParameter reference="ModelValue_205"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_665">
              <SourceParameter reference="ModelValue_206"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_60" name="BUD Degr" reversible="false" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_60">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:06:23Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfSubstrates>
          <Substrate metabolite="Metabolite_71" stoichiometry="1"/>
        </ListOfSubstrates>
        <ListOfConstants>
          <Constant key="Parameter_3384" name="k1" value="0.059"/>
        </ListOfConstants>
        <KineticLaw function="Function_13" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_81">
              <SourceParameter reference="ModelValue_201"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_79">
              <SourceParameter reference="Metabolite_71"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_59" name="ORI Synth" reversible="false" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_59">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:08:50Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfProducts>
          <Product metabolite="Metabolite_70" stoichiometry="1"/>
        </ListOfProducts>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_54" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_53" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3383" name="e_ori_b2" value="0.124"/>
          <Constant key="Parameter_3382" name="e_ori_b5" value="5.04"/>
          <Constant key="Parameter_3381" name="ks_ori_e" value="1.9"/>
        </ListOfConstants>
        <KineticLaw function="Function_86" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_636">
              <SourceParameter reference="Metabolite_53"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_656">
              <SourceParameter reference="Metabolite_54"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_675">
              <SourceParameter reference="ModelValue_195"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_676">
              <SourceParameter reference="ModelValue_196"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_677">
              <SourceParameter reference="ModelValue_197"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_58" name="ORI Degr" reversible="false" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_58">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:09:26Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfSubstrates>
          <Substrate metabolite="Metabolite_70" stoichiometry="1"/>
        </ListOfSubstrates>
        <ListOfConstants>
          <Constant key="Parameter_3380" name="k1" value="0.0817"/>
        </ListOfConstants>
        <KineticLaw function="Function_13" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_81">
              <SourceParameter reference="ModelValue_194"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_79">
              <SourceParameter reference="Metabolite_70"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_57" name="SPN Synth" reversible="false" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_57">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:09:51Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfProducts>
          <Product metabolite="Metabolite_69" stoichiometry="1"/>
        </ListOfProducts>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_53" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3379" name="Jspn" value="0.809"/>
          <Constant key="Parameter_3378" name="ks_spn" value="0.0743"/>
        </ListOfConstants>
        <KineticLaw function="Function_87" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_683">
              <SourceParameter reference="Metabolite_53"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_684">
              <SourceParameter reference="ModelValue_198"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_685">
              <SourceParameter reference="ModelValue_200"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_56" name="SPN Degr" reversible="false" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_56">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:10:24Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfSubstrates>
          <Substrate metabolite="Metabolite_69" stoichiometry="1"/>
        </ListOfSubstrates>
        <ListOfConstants>
          <Constant key="Parameter_3377" name="k1" value="0.0384"/>
        </ListOfConstants>
        <KineticLaw function="Function_13" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_81">
              <SourceParameter reference="ModelValue_199"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_79">
              <SourceParameter reference="Metabolite_69"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_55" name="SWI5T Synth" reversible="false" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_55">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:11:54Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfProducts>
          <Product metabolite="Metabolite_68" stoichiometry="1"/>
        </ListOfProducts>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_48" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3376" name="ks_swi5" value="0.00558"/>
          <Constant key="Parameter_3375" name="ks_swi5_m1" value="0.0389"/>
        </ListOfConstants>
        <KineticLaw function="Function_88" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_691">
              <SourceParameter reference="Metabolite_48"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_692">
              <SourceParameter reference="ModelValue_193"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_693">
              <SourceParameter reference="ModelValue_192"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_54" name="SWI5T Degr" reversible="false" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_54">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:13:43Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfSubstrates>
          <Substrate metabolite="Metabolite_68" stoichiometry="1"/>
        </ListOfSubstrates>
        <ListOfConstants>
          <Constant key="Parameter_3374" name="k1" value="0.042"/>
        </ListOfConstants>
        <KineticLaw function="Function_13" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_81">
              <SourceParameter reference="ModelValue_191"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_79">
              <SourceParameter reference="Metabolite_68"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_53" name="CDC20T Synth" reversible="false" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_53">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:11:31Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfProducts>
          <Product metabolite="Metabolite_67" stoichiometry="1"/>
        </ListOfProducts>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_48" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3373" name="ks_20" value="0.0221"/>
          <Constant key="Parameter_3372" name="ks_20_m1" value="0.354"/>
        </ListOfConstants>
        <KineticLaw function="Function_89" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_699">
              <SourceParameter reference="Metabolite_48"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_700">
              <SourceParameter reference="ModelValue_186"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_701">
              <SourceParameter reference="ModelValue_185"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_52" name="CDC20T Degr" reversible="false" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_52">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:14:33Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfSubstrates>
          <Substrate metabolite="Metabolite_67" stoichiometry="1"/>
        </ListOfSubstrates>
        <ListOfConstants>
          <Constant key="Parameter_3371" name="k1" value="0.124"/>
        </ListOfConstants>
        <KineticLaw function="Function_13" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_81">
              <SourceParameter reference="ModelValue_184"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_79">
              <SourceParameter reference="Metabolite_67"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_51" name="CDC20A_APCP Synth" reversible="true" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_51">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:17:25Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfProducts>
          <Product metabolite="Metabolite_66" stoichiometry="1"/>
        </ListOfProducts>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_46" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_70" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_69" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3370" name="gamma" value="2.22"/>
          <Constant key="Parameter_3369" name="ka_20" value="0.0104"/>
          <Constant key="Parameter_3368" name="kd_20" value="0.124"/>
          <Constant key="Parameter_3367" name="ki_20_ori" value="5.04"/>
          <Constant key="Parameter_3366" name="sig" value="9.63"/>
        </ListOfConstants>
        <KineticLaw function="Function_90" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_721">
              <SourceParameter reference="Metabolite_66"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_720">
              <SourceParameter reference="Metabolite_46"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_719">
              <SourceParameter reference="Metabolite_70"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_718">
              <SourceParameter reference="Metabolite_69"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_717">
              <SourceParameter reference="ModelValue_247"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_716">
              <SourceParameter reference="ModelValue_183"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_715">
              <SourceParameter reference="ModelValue_184"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_714">
              <SourceParameter reference="ModelValue_180"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_713">
              <SourceParameter reference="ModelValue_243"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_50" name="APCP Synth" reversible="true" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_50">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:21:13Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfProducts>
          <Product metabolite="Metabolite_65" stoichiometry="1"/>
        </ListOfProducts>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_53" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3365" name="APCPT" value="45.7"/>
          <Constant key="Parameter_3364" name="gammacp" value="1.34"/>
          <Constant key="Parameter_3363" name="ka_cp_b2" value="0.334"/>
          <Constant key="Parameter_3362" name="ki_cp" value="0.21"/>
          <Constant key="Parameter_3361" name="sig" value="9.63"/>
        </ListOfConstants>
        <KineticLaw function="Function_91" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_705">
              <SourceParameter reference="Metabolite_65"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_711">
              <SourceParameter reference="ModelValue_136"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_731">
              <SourceParameter reference="Metabolite_53"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_732">
              <SourceParameter reference="ModelValue_245"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_733">
              <SourceParameter reference="ModelValue_179"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_734">
              <SourceParameter reference="ModelValue_178"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_735">
              <SourceParameter reference="ModelValue_243"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_49" name="CDH1A Synth" reversible="true" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_49">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:22:42Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfProducts>
          <Product metabolite="Metabolite_64" stoichiometry="1"/>
        </ListOfProducts>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_51" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_79" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_76" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_54" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_53" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3360" name="CDH1T" value="0.808"/>
          <Constant key="Parameter_3359" name="e_h1_b2" value="2.35"/>
          <Constant key="Parameter_3358" name="e_h1_b5" value="9.73"/>
          <Constant key="Parameter_3357" name="e_h1_n2" value="1.56"/>
          <Constant key="Parameter_3356" name="e_h1_n3" value="3.75"/>
          <Constant key="Parameter_3355" name="gamma" value="2.22"/>
          <Constant key="Parameter_3354" name="ka_h1" value="0.241"/>
          <Constant key="Parameter_3353" name="ka_h1_14" value="32.2"/>
          <Constant key="Parameter_3352" name="ki_h1" value="0.144"/>
          <Constant key="Parameter_3351" name="ki_h1_e" value="0.215"/>
          <Constant key="Parameter_3350" name="sig" value="9.63"/>
        </ListOfConstants>
        <KineticLaw function="Function_92" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_753">
              <SourceParameter reference="Metabolite_51"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_754">
              <SourceParameter reference="Metabolite_64"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_755">
              <SourceParameter reference="ModelValue_135"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_756">
              <SourceParameter reference="Metabolite_53"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_757">
              <SourceParameter reference="Metabolite_54"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_758">
              <SourceParameter reference="Metabolite_76"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_759">
              <SourceParameter reference="Metabolite_79"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_760">
              <SourceParameter reference="ModelValue_170"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_761">
              <SourceParameter reference="ModelValue_171"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_762">
              <SourceParameter reference="ModelValue_172"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_763">
              <SourceParameter reference="ModelValue_173"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_764">
              <SourceParameter reference="ModelValue_247"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_765">
              <SourceParameter reference="ModelValue_177"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_766">
              <SourceParameter reference="ModelValue_176"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_767">
              <SourceParameter reference="ModelValue_175"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_768">
              <SourceParameter reference="ModelValue_174"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_769">
              <SourceParameter reference="ModelValue_243"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_48" name="NET1deP Synth" reversible="true" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_48">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:26:49Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfProducts>
          <Product metabolite="Metabolite_63" stoichiometry="1"/>
        </ListOfProducts>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_51" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_62" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_53" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_49" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_60" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3349" name="NET1T" value="6.4"/>
          <Constant key="Parameter_3348" name="gamma" value="2.22"/>
          <Constant key="Parameter_3347" name="kdp_net" value="0.106"/>
          <Constant key="Parameter_3346" name="kdp_net_14" value="0.00663"/>
          <Constant key="Parameter_3345" name="kdp_net_px" value="83.3"/>
          <Constant key="Parameter_3344" name="kp_net" value="0.556"/>
          <Constant key="Parameter_3343" name="kp_net_15" value="0.00881"/>
          <Constant key="Parameter_3342" name="kp_net_b2" value="1.5"/>
          <Constant key="Parameter_3341" name="kp_net_en" value="6.88"/>
          <Constant key="Parameter_3340" name="signet" value="1.52"/>
        </ListOfConstants>
        <KineticLaw function="Function_93" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_708">
              <SourceParameter reference="Metabolite_51"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_787">
              <SourceParameter reference="Metabolite_60"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_788">
              <SourceParameter reference="Metabolite_53"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_789">
              <SourceParameter reference="Metabolite_49"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_790">
              <SourceParameter reference="ModelValue_134"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_791">
              <SourceParameter reference="Metabolite_63"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_792">
              <SourceParameter reference="Metabolite_62"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_793">
              <SourceParameter reference="ModelValue_247"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_794">
              <SourceParameter reference="ModelValue_169"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_795">
              <SourceParameter reference="ModelValue_168"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_796">
              <SourceParameter reference="ModelValue_167"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_797">
              <SourceParameter reference="ModelValue_166"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_798">
              <SourceParameter reference="ModelValue_163"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_799">
              <SourceParameter reference="ModelValue_165"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_800">
              <SourceParameter reference="ModelValue_164"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_801">
              <SourceParameter reference="ModelValue_242"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_47" name="PPX Synth" reversible="true" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_47">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:29:21Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfProducts>
          <Product metabolite="Metabolite_62" stoichiometry="1"/>
        </ListOfProducts>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_50" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3339" name="PPXT" value="0.866"/>
          <Constant key="Parameter_3338" name="gamma" value="2.22"/>
          <Constant key="Parameter_3337" name="ka_px" value="0.055"/>
          <Constant key="Parameter_3336" name="ki_px" value="0.119"/>
          <Constant key="Parameter_3335" name="ki_px_p1" value="6.69"/>
          <Constant key="Parameter_3334" name="sig" value="9.63"/>
        </ListOfConstants>
        <KineticLaw function="Function_94" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_707">
              <SourceParameter reference="Metabolite_50"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_746">
              <SourceParameter reference="Metabolite_62"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_752">
              <SourceParameter reference="ModelValue_132"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_743">
              <SourceParameter reference="ModelValue_247"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_749">
              <SourceParameter reference="ModelValue_162"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_745">
              <SourceParameter reference="ModelValue_161"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_710">
              <SourceParameter reference="ModelValue_160"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_712">
              <SourceParameter reference="ModelValue_243"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_46" name="PDS1T Synth" reversible="false" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_46">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:30:52Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfProducts>
          <Product metabolite="Metabolite_61" stoichiometry="1"/>
        </ListOfProducts>
        <ListOfConstants>
          <Constant key="Parameter_3333" name="v" value="0.0467"/>
        </ListOfConstants>
        <KineticLaw function="Function_6" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_49">
              <SourceParameter reference="ModelValue_159"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_45" name="PDS1T Degr" reversible="false" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_45">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:31:06Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfSubstrates>
          <Substrate metabolite="Metabolite_61" stoichiometry="1"/>
        </ListOfSubstrates>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_66" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_56" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3332" name="kd_pds" value="0.0144"/>
          <Constant key="Parameter_3331" name="kd_pds_20_i" value="0.125"/>
          <Constant key="Parameter_3330" name="ks_pds_20" value="3.04"/>
        </ListOfConstants>
        <KineticLaw function="Function_95" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_830">
              <SourceParameter reference="Metabolite_66"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_829">
              <SourceParameter reference="Metabolite_56"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_828">
              <SourceParameter reference="Metabolite_61"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_827">
              <SourceParameter reference="ModelValue_158"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_826">
              <SourceParameter reference="ModelValue_128"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_706">
              <SourceParameter reference="ModelValue_157"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_44" name="CDC15 Synth" reversible="true" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_44">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:33:11Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfProducts>
          <Product metabolite="Metabolite_60" stoichiometry="1"/>
        </ListOfProducts>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_51" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_53" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3329" name="CDC15T" value="1.02"/>
          <Constant key="Parameter_3328" name="gamma" value="2.22"/>
          <Constant key="Parameter_3327" name="ka_15" value="0.709"/>
          <Constant key="Parameter_3326" name="ka_15_14" value="7.38"/>
          <Constant key="Parameter_3325" name="ki_15" value="0.894"/>
          <Constant key="Parameter_3324" name="ki_15_b2" value="2.16"/>
          <Constant key="Parameter_3323" name="sig" value="9.63"/>
        </ListOfConstants>
        <KineticLaw function="Function_96" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_841">
              <SourceParameter reference="Metabolite_51"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_842">
              <SourceParameter reference="Metabolite_60"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_843">
              <SourceParameter reference="ModelValue_130"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_844">
              <SourceParameter reference="Metabolite_53"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_845">
              <SourceParameter reference="ModelValue_247"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_846">
              <SourceParameter reference="ModelValue_156"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_847">
              <SourceParameter reference="ModelValue_155"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_848">
              <SourceParameter reference="ModelValue_154"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_849">
              <SourceParameter reference="ModelValue_153"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_850">
              <SourceParameter reference="ModelValue_243"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_43" name="TEM1 Synth" reversible="true" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_43">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:34:57Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfProducts>
          <Product metabolite="Metabolite_59" stoichiometry="1"/>
        </ListOfProducts>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_57" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_50" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_62" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3322" name="TEM1T" value="1.29"/>
          <Constant key="Parameter_3321" name="gammatem" value="0.369"/>
          <Constant key="Parameter_3320" name="ka_tem" value="0.0848"/>
          <Constant key="Parameter_3319" name="ka_tem_lo" value="3.84"/>
          <Constant key="Parameter_3318" name="ka_tem_p1" value="0.0638"/>
          <Constant key="Parameter_3317" name="ki_tem" value="0.323"/>
          <Constant key="Parameter_3316" name="ki_tem_px" value="1.92"/>
          <Constant key="Parameter_3315" name="sig" value="9.63"/>
        </ListOfConstants>
        <KineticLaw function="Function_97" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_863">
              <SourceParameter reference="Metabolite_50"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_864">
              <SourceParameter reference="Metabolite_57"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_865">
              <SourceParameter reference="Metabolite_62"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_866">
              <SourceParameter reference="Metabolite_59"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_867">
              <SourceParameter reference="ModelValue_129"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_868">
              <SourceParameter reference="ModelValue_244"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_869">
              <SourceParameter reference="ModelValue_152"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_870">
              <SourceParameter reference="ModelValue_151"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_871">
              <SourceParameter reference="ModelValue_150"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_872">
              <SourceParameter reference="ModelValue_149"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_873">
              <SourceParameter reference="ModelValue_148"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_874">
              <SourceParameter reference="ModelValue_243"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_42" name="POLOT Synth" reversible="false" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_42">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:37:58Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfProducts>
          <Product metabolite="Metabolite_58" stoichiometry="1"/>
        </ListOfProducts>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_48" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3314" name="ks_lo" value="0.045"/>
          <Constant key="Parameter_3313" name="ks_lo_m1" value="0.0113"/>
        </ListOfConstants>
        <KineticLaw function="Function_98" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_839">
              <SourceParameter reference="Metabolite_48"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_698">
              <SourceParameter reference="ModelValue_147"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_747">
              <SourceParameter reference="ModelValue_146"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_41" name="POLOT Degr" reversible="false" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_41">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:38:40Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfSubstrates>
          <Substrate metabolite="Metabolite_58" stoichiometry="1"/>
        </ListOfSubstrates>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_64" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3312" name="kd_lo" value="0.00483"/>
          <Constant key="Parameter_3311" name="kd_lo_h1" value="0.139"/>
        </ListOfConstants>
        <KineticLaw function="Function_99" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_748">
              <SourceParameter reference="Metabolite_64"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_709">
              <SourceParameter reference="Metabolite_58"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_887">
              <SourceParameter reference="ModelValue_145"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_888">
              <SourceParameter reference="ModelValue_144"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_40" name="POLOA Synth" reversible="true" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_40">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:39:37Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfProducts>
          <Product metabolite="Metabolite_57" stoichiometry="1"/>
        </ListOfProducts>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_58" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_53" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_64" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3310" name="gamma" value="2.22"/>
          <Constant key="Parameter_3309" name="ka_lo" value="0.0232"/>
          <Constant key="Parameter_3308" name="ka_lo_b2" value="1.11"/>
          <Constant key="Parameter_3307" name="kd_lo" value="0.00483"/>
          <Constant key="Parameter_3306" name="kd_lo_h1" value="0.139"/>
          <Constant key="Parameter_3305" name="ki_lo" value="0.965"/>
          <Constant key="Parameter_3304" name="sig" value="9.63"/>
        </ListOfConstants>
        <KineticLaw function="Function_100" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_900">
              <SourceParameter reference="Metabolite_64"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_901">
              <SourceParameter reference="Metabolite_53"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_902">
              <SourceParameter reference="Metabolite_57"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_903">
              <SourceParameter reference="Metabolite_58"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_904">
              <SourceParameter reference="ModelValue_247"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_905">
              <SourceParameter reference="ModelValue_143"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_906">
              <SourceParameter reference="ModelValue_142"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_907">
              <SourceParameter reference="ModelValue_145"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_908">
              <SourceParameter reference="ModelValue_144"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_909">
              <SourceParameter reference="ModelValue_141"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_910">
              <SourceParameter reference="ModelValue_243"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
      <Reaction key="Reaction_39" name="CDC20A_APC Synth" reversible="true" fast="false">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Reaction_39">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-01-06T14:45:13Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <ListOfProducts>
          <Product metabolite="Metabolite_56" stoichiometry="1"/>
        </ListOfProducts>
        <ListOfModifiers>
          <Modifier metabolite="Metabolite_45" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_70" stoichiometry="1"/>
          <Modifier metabolite="Metabolite_69" stoichiometry="1"/>
        </ListOfModifiers>
        <ListOfConstants>
          <Constant key="Parameter_3303" name="gamma" value="2.22"/>
          <Constant key="Parameter_3302" name="ka_20" value="0.0104"/>
          <Constant key="Parameter_3301" name="kd_20" value="0.124"/>
          <Constant key="Parameter_3300" name="ki_20_ori" value="5.04"/>
          <Constant key="Parameter_3299" name="sig" value="9.63"/>
        </ListOfConstants>
        <KineticLaw function="Function_101" unitType="Default" scalingCompartment="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]">
          <ListOfCallParameters>
            <CallParameter functionParameter="FunctionParameter_894">
              <SourceParameter reference="Metabolite_56"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_899">
              <SourceParameter reference="Metabolite_45"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_922">
              <SourceParameter reference="Metabolite_70"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_923">
              <SourceParameter reference="Metabolite_69"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_924">
              <SourceParameter reference="ModelValue_247"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_925">
              <SourceParameter reference="ModelValue_183"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_926">
              <SourceParameter reference="ModelValue_184"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_927">
              <SourceParameter reference="ModelValue_180"/>
            </CallParameter>
            <CallParameter functionParameter="FunctionParameter_928">
              <SourceParameter reference="ModelValue_243"/>
            </CallParameter>
          </ListOfCallParameters>
        </KineticLaw>
      </Reaction>
    </ListOfReactions>
    <ListOfEvents>
      <Event key="Event_18" name="Cell division" delayAssignment="true" fireAtInitialTime="0" persistentTrigger="1">
        <MiriamAnnotation>
<rdf:RDF
   xmlns:dcterms="http://purl.org/dc/terms/"
   xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Event_18">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-04-17T10:19:41Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>

        </MiriamAnnotation>
        <TriggerExpression>
          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CLB2],Reference=Concentration> lt 0.20000000000000001 and &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[OK_DIV],Reference=Concentration> eq 1
        </TriggerExpression>
        <DelayExpression>
          0
        </DelayExpression>
        <ListOfAssignments>
          <Assignment targetKey="Metabolite_81">
            <Expression>
              &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[V],Reference=Concentration>*&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[f],Reference=Value>
            </Expression>
          </Assignment>
          <Assignment targetKey="Metabolite_71">
            <Expression>
              0
            </Expression>
          </Assignment>
          <Assignment targetKey="Metabolite_44">
            <Expression>
              &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[DIV_COUNT],Reference=Concentration>+1
            </Expression>
          </Assignment>
          <Assignment targetKey="Metabolite_43">
            <Expression>
              0
            </Expression>
          </Assignment>
          <Assignment targetKey="Metabolite_41">
            <Expression>
              0
            </Expression>
          </Assignment>
          <Assignment targetKey="Metabolite_42">
            <Expression>
              0
            </Expression>
          </Assignment>
          <Assignment targetKey="Metabolite_107">
            <Expression>
              &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[V],Reference=Concentration>
            </Expression>
          </Assignment>
          <Assignment targetKey="Metabolite_108">
            <Expression>
              &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[VDiv1],Reference=Concentration>
            </Expression>
          </Assignment>
          <Assignment targetKey="Metabolite_109">
            <Expression>
              &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[VDiv2],Reference=Concentration>
            </Expression>
          </Assignment>
        </ListOfAssignments>
      </Event>
      <Event key="Event_4" name="Origin relicensing" delayAssignment="true" fireAtInitialTime="0" persistentTrigger="1">
        <MiriamAnnotation>
<rdf:RDF
   xmlns:dcterms="http://purl.org/dc/terms/"
   xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Event_4">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-04-17T10:19:37Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>

        </MiriamAnnotation>
        <TriggerExpression>
          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CLB2],Reference=Concentration>+&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CLB5],Reference=Concentration> lt 0.20000000000000001 and &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[OK_LICENSE],Reference=Concentration> eq 1
        </TriggerExpression>
        <DelayExpression>
          0
        </DelayExpression>
        <ListOfAssignments>
          <Assignment targetKey="Metabolite_70">
            <Expression>
              0
            </Expression>
          </Assignment>
          <Assignment targetKey="Metabolite_69">
            <Expression>
              0
            </Expression>
          </Assignment>
        </ListOfAssignments>
      </Event>
      <Event key="Event_9" name="Bud emergence" delayAssignment="true" fireAtInitialTime="0" persistentTrigger="1">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Event_9">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-04-17T10:19:42Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <TriggerExpression>
          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[BUD],Reference=Concentration> ge 1
        </TriggerExpression>
        <DelayExpression>
          0
        </DelayExpression>
        <ListOfAssignments>
          <Assignment targetKey="Metabolite_43">
            <Expression>
              1
            </Expression>
          </Assignment>
        </ListOfAssignments>
      </Event>
      <Event key="Event_8" name="ORI activation" delayAssignment="true" fireAtInitialTime="0" persistentTrigger="1">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Event_8">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-04-17T10:19:37Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <TriggerExpression>
          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[ORI],Reference=Concentration> ge 1
        </TriggerExpression>
        <DelayExpression>
          0
        </DelayExpression>
        <ListOfAssignments>
          <Assignment targetKey="Metabolite_42">
            <Expression>
              1
            </Expression>
          </Assignment>
        </ListOfAssignments>
      </Event>
      <Event key="Event_7" name="SPN completion" delayAssignment="true" fireAtInitialTime="0" persistentTrigger="1">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Event_7">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-04-17T10:19:38Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <TriggerExpression>
          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[SPN],Reference=Concentration> ge 1
        </TriggerExpression>
        <DelayExpression>
          0
        </DelayExpression>
        <ListOfAssignments>
          <Assignment targetKey="Metabolite_41">
            <Expression>
              1
            </Expression>
          </Assignment>
        </ListOfAssignments>
      </Event>
      <Event key="Event_6" name="Cln3 peak" fireAtInitialTime="0" persistentTrigger="0">
        <MiriamAnnotation>
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Event_6">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-04-16T16:26:32Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
</rdf:RDF>
        </MiriamAnnotation>
        <TriggerExpression>
          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[dCLN3],Reference=Concentration> lt 0
        </TriggerExpression>
        <ListOfAssignments>
          <Assignment targetKey="Metabolite_96">
            <Expression>
              &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CLN3_peaks],Reference=Concentration>+1
            </Expression>
          </Assignment>
        </ListOfAssignments>
      </Event>
      <Event key="Event_5" name="Bck2 peak" fireAtInitialTime="0" persistentTrigger="0">
        <MiriamAnnotation>
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  <rdf:Description rdf:about="#Event_5">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-04-17T09:23:46Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
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        </MiriamAnnotation>
        <TriggerExpression>
          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[dBCK2],Reference=Concentration> lt 0
        </TriggerExpression>
        <ListOfAssignments>
          <Assignment targetKey="Metabolite_97">
            <Expression>
              &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[BCK2_peaks],Reference=Concentration>+1
            </Expression>
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        </ListOfAssignments>
      </Event>
      <Event key="Event_25" name="Cln2 peak" fireAtInitialTime="0" persistentTrigger="0">
        <MiriamAnnotation>
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    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-04-17T09:23:52Z</dcterms:W3CDTF>
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        </MiriamAnnotation>
        <TriggerExpression>
          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[dCLN2],Reference=Concentration> lt 0
        </TriggerExpression>
        <ListOfAssignments>
          <Assignment targetKey="Metabolite_98">
            <Expression>
              &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CLN2_peaks],Reference=Concentration>+1
            </Expression>
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      </Event>
      <Event key="Event_24" name="CKIT peak" fireAtInitialTime="0" persistentTrigger="0">
        <MiriamAnnotation>
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    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-04-17T09:25:15Z</dcterms:W3CDTF>
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        </MiriamAnnotation>
        <TriggerExpression>
          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[dCKIT],Reference=Concentration> lt 0
        </TriggerExpression>
        <ListOfAssignments>
          <Assignment targetKey="Metabolite_99">
            <Expression>
              &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CKIT_peaks],Reference=Concentration>+1
            </Expression>
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      </Event>
      <Event key="Event_10" name="Clb5T peak" fireAtInitialTime="0" persistentTrigger="0">
        <MiriamAnnotation>
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  <rdf:Description rdf:about="#Event_10">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-04-17T09:27:12Z</dcterms:W3CDTF>
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        </MiriamAnnotation>
        <TriggerExpression>
          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[dCLB5T],Reference=Concentration> lt 0
        </TriggerExpression>
        <ListOfAssignments>
          <Assignment targetKey="Metabolite_100">
            <Expression>
              &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CLB5T_peaks],Reference=Concentration>+1
            </Expression>
          </Assignment>
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      </Event>
      <Event key="Event_11" name="Clb2T peak" fireAtInitialTime="0" persistentTrigger="0">
        <MiriamAnnotation>
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  <rdf:Description rdf:about="#Event_11">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-04-17T09:26:04Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
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        </MiriamAnnotation>
        <TriggerExpression>
          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[dCLB2T],Reference=Concentration> lt 0
        </TriggerExpression>
        <ListOfAssignments>
          <Assignment targetKey="Metabolite_101">
            <Expression>
              &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CLB2T_peaks],Reference=Concentration>+1
            </Expression>
          </Assignment>
        </ListOfAssignments>
      </Event>
      <Event key="Event_12" name="Swi5T peak" fireAtInitialTime="0" persistentTrigger="0">
        <MiriamAnnotation>
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  <rdf:Description rdf:about="#Event_12">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-04-17T09:32:33Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
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        </MiriamAnnotation>
        <TriggerExpression>
          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[dPOLOT],Reference=Concentration> lt 0
        </TriggerExpression>
        <ListOfAssignments>
          <Assignment targetKey="Metabolite_102">
            <Expression>
              &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[SWI5T_peaks],Reference=Concentration>+1
            </Expression>
          </Assignment>
        </ListOfAssignments>
      </Event>
      <Event key="Event_15" name="CDC20T peak" fireAtInitialTime="0" persistentTrigger="0">
        <MiriamAnnotation>
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  <rdf:Description rdf:about="#Event_15">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-04-17T09:24:37Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
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        </MiriamAnnotation>
        <TriggerExpression>
          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[dCDC20T],Reference=Concentration> lt 0
        </TriggerExpression>
        <ListOfAssignments>
          <Assignment targetKey="Metabolite_103">
            <Expression>
              &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CDC20T_peaks],Reference=Concentration>+1
            </Expression>
          </Assignment>
        </ListOfAssignments>
      </Event>
      <Event key="Event_16" name="PDS1T peak" fireAtInitialTime="0" persistentTrigger="0">
        <MiriamAnnotation>
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  <rdf:Description rdf:about="#Event_16">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-04-17T09:29:01Z</dcterms:W3CDTF>
      </rdf:Description>
    </dcterms:created>
  </rdf:Description>
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        </MiriamAnnotation>
        <TriggerExpression>
          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[dPDS1T],Reference=Concentration> lt 0
        </TriggerExpression>
        <ListOfAssignments>
          <Assignment targetKey="Metabolite_104">
            <Expression>
              &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[PDS1T_peaks],Reference=Concentration>+1
            </Expression>
          </Assignment>
        </ListOfAssignments>
      </Event>
      <Event key="Event_19" name="POLOT peak" fireAtInitialTime="0" persistentTrigger="0">
        <MiriamAnnotation>
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  <rdf:Description rdf:about="#Event_19">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-04-17T09:30:03Z</dcterms:W3CDTF>
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        </MiriamAnnotation>
        <TriggerExpression>
          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[dPOLOT],Reference=Concentration> lt 0
        </TriggerExpression>
        <ListOfAssignments>
          <Assignment targetKey="Metabolite_105">
            <Expression>
              &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[POLOT_peaks],Reference=Concentration>+1
            </Expression>
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      </Event>
      <Event key="Event_17" name="Allow division" fireAtInitialTime="0" persistentTrigger="0">
        <MiriamAnnotation>
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   xmlns:dcterms="http://purl.org/dc/terms/"
   xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Event_17">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-05-01T14:40:46Z</dcterms:W3CDTF>
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        </MiriamAnnotation>
        <TriggerExpression>
          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[OK_DIV],Reference=Concentration> eq 0 and &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CLB2],Reference=Concentration> gt 0.2
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        <ListOfAssignments>
          <Assignment targetKey="Metabolite_40">
            <Expression>
              1
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      <Event key="Event_28" name="Allow relicensing" fireAtInitialTime="0" persistentTrigger="0">
        <MiriamAnnotation>
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   xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
  <rdf:Description rdf:about="#Event_28">
    <dcterms:created>
      <rdf:Description>
        <dcterms:W3CDTF>2018-05-01T14:41:43Z</dcterms:W3CDTF>
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        </MiriamAnnotation>
        <TriggerExpression>
          &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[OK_LICENSE],Reference=Concentration> eq 0 and &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CLB2],Reference=Concentration>+&lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CLB5],Reference=Concentration> gt 0.2
        </TriggerExpression>
        <ListOfAssignments>
          <Assignment targetKey="Metabolite_39">
            <Expression>
              1
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          </Assignment>
        </ListOfAssignments>
      </Event>
    </ListOfEvents>
    <ListOfModelParameterSets activeSet="ModelParameterSet_2">
      <ModelParameterSet key="ModelParameterSet_2" name="Initial State">
        <ModelParameterGroup cn="String=Initial Time" type="Group">
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1" value="0" type="Model" simulationType="time"/>
        </ModelParameterGroup>
        <ModelParameterGroup cn="String=Initial Compartment Sizes" type="Group">
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell]" value="1" type="Compartment" simulationType="fixed"/>
        </ModelParameterGroup>
        <ModelParameterGroup cn="String=Initial Species Values" type="Group">
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[V]" value="2.7701847942200001e+23" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[BCK2]" value="1.2586274391129999e+22" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CLN3]" value="4.3660521213250001e+23" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[WHI5deP]" value="1.065918931689e+24" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[SBFdeP]" value="4.0830115010460004e+23" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CLN2]" value="3.7698601764820001e+22" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CKIT]" value="3.3483103164919997e+22" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CKIP]" value="2.1077492999500002e+22" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CLB5T]" value="3.1254911047830002e+22" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CLB2T]" value="8.9127684683600002e+21" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[BUD]" value="1.4453138056800002e+22" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[ORI]" value="3.9565465430489997e+22" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[SPN]" value="8.9729898769300001e+22" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[SWI5T]" value="7.3470118455400001e+22" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CDC20T]" value="4.8357791081710003e+22" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CDC20A_APCP]" value="1.56575662282e+23" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[APCP]" value="8.9127684683599997e+23" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CDH1A]" value="1.6560887356750001e+24" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[NET1deP]" value="1.4874687916790001e+24" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[PPX]" value="1.9451514968110002e+23" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[PDS1T]" value="1.4212252422519999e+23" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CDC15]" value="3.8903029936220005e+23" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[TEM1]" value="4.293786431041e+22" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[POLOT]" value="5.5825245744390006e+22" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[POLOA]" value="6.0040744344289997e+22" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CDC20A_APC]" value="3.2218453584950002e+22" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[FuncSafety]" value="2.0721811535692416e+25" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CLB5]" value="5.1245127419632697e+21" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CLB2]" value="1.4613254061860575e+21" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[SBF]" value="0" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CDC14]" value="0" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[ESP1]" value="1.6861994399600015e+22" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[MEN]" value="4.293786431041e+22" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[MCM1]" value="1257024356.8376269" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[SWI5A]" value="3.6723041258761773e+22" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CDC20A_APCP_T]" value="4.8357791081710003e+22" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CDC20A_APC_T]" value="0" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[DIV_COUNT]" value="0" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[FLAG_BUD]" value="0" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[FLAG_UDNA]" value="0" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[FLAG_SPC]" value="0" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CLB2CLB5]" value="6.5858381481493272e+21" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[dCLN3]" value="-2.9780481722159167e+23" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[dBCK2]" value="-2.2565564005264694e+22" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[dCLN2]" value="-1.2063492343333831e+21" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[dCKIT]" value="-1.2337690118997716e+22" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[dCLB5T]" value="-1.7837284429266144e+21" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[dCLB2T]" value="-1.4458904355433668e+22" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[dSWI5T]" value="2.7460962307924899e+20" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[dCDC20T]" value="7.3125651998384062e+21" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[dPDS1T]" value="-8.720725407500697e+22" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[dPOLOT]" value="5.4907977337615281e+21" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CLN3_peaks]" value="0" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[BCK2_peaks]" value="0" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CLN2_peaks]" value="0" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CKIT_peaks]" value="0" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CLB5T_peaks]" value="0" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CLB2T_peaks]" value="0" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[SWI5T_peaks]" value="0" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[CDC20T_peaks]" value="0" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[PDS1T_peaks]" value="0" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[POLOT_peaks]" value="0" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[OffsetTime]" value="0" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[VDiv1]" value="0" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[VDiv2]" value="0" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[VDiv3]" value="0" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[DIff1]" value="0" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[Diff2]" value="0" type="Species" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[OK_DIV]" value="0" type="Species" simulationType="reactions"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Compartments[cell],Vector=Metabolites[OK_LICENSE]" value="0" type="Species" simulationType="reactions"/>
        </ModelParameterGroup>
        <ModelParameterGroup cn="String=Initial Global Quantities" type="Group">
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[mdt]" value="90" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[mu]" value="0.0077016353395549476" type="ModelValue" simulationType="assignment"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_n3]" value="1.1100000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[Dn3]" value="0.73199999999999998" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[Jn3]" value="4.2699999999999996" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_n3]" value="0.79400000000000004" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[gamma]" value="2.2200000000000002" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[gammaki]" value="12.9" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[gammacp]" value="1.3400000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[gammatem]" value="0.36899999999999999" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[sig]" value="9.6300000000000008" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[signet]" value="1.52" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_k2]" value="0.055300000000000002" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_k2]" value="3.0099999999999998" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kdp_i5]" value="1.22" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kdp_i5_14]" value="0.19500000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kp_i5]" value="0.0275" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kp_i5_n3]" value="6.0999999999999996" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kp_i5_k2]" value="23.699999999999999" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kp_i5_n2]" value="2.9700000000000002" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kp_i5_b5]" value="0.042200000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kdp_bf]" value="2.9300000000000002" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kp_bf_b2]" value="9.3599999999999994" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_n2]" value="1e-08" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_n2_bf]" value="0.996" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_n2]" value="0.032000000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_ki]" value="0.0066299999999999996" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_ki_swi5]" value="0.088999999999999996" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_ki]" value="0.052400000000000002" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_kip]" value="0.89900000000000002" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kp_ki_e]" value="0.65000000000000002" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_ki_n3]" value="1.05" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_ki_k2]" value="0.39700000000000002" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_ki_n2]" value="19.5" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_ki_b5]" value="2.3900000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_ki_b2]" value="3.1200000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kdp_ki]" value="0.83599999999999997" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kdp_ki_14]" value="1.1100000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_b5]" value="0.00053799999999999996" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_b5_bf]" value="0.0178" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_b5]" value="0.055599999999999997" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_b5_20]" value="0.044499999999999998" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_b2]" value="0.00762" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_b2_m1]" value="0.031" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_b2]" value="0.00298" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_b2_20]" value="0.13600000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_b2_h1]" value="0.66200000000000003" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_bud_e]" value="0.28699999999999998" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_bud_n3]" value="0.0077999999999999996" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_bud_n2]" value="1.1200000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_bud_b5]" value="3" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_bud_b2]" value="1.8899999999999999" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_bud]" value="0.058999999999999997" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_spn]" value="0.074300000000000005" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_spn]" value="0.038399999999999997" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[Jspn]" value="0.80900000000000005" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_ori_e]" value="1.8999999999999999" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_ori_b5]" value="5.04" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_ori_b2]" value="0.124" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_ori]" value="0.081699999999999995" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_swi5]" value="0.0055799999999999999" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_swi5_m1]" value="0.038899999999999997" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_swi5]" value="0.042000000000000003" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ka_swi5_14]" value="1.4099999999999999" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ki_swi5_b2]" value="0.028000000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ka_m1_b2]" value="4.6500000000000004" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ki_m1]" value="3.3900000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_20]" value="0.022100000000000002" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_20_m1]" value="0.35399999999999998" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_20]" value="0.124" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ka_20]" value="0.0104" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_b5_20_i]" value="0.0049800000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_b2_20_i]" value="0.037400000000000003" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ki_20_ori]" value="5.04" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ka_cp_b2]" value="0.33400000000000002" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ki_cp]" value="0.20999999999999999" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ka_h1]" value="0.24099999999999999" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ka_h1_14]" value="32.200000000000003" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ki_h1]" value="0.14399999999999999" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ki_h1_e]" value="0.215" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_h1_n3]" value="3.75" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_h1_n2]" value="1.5600000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_h1_b5]" value="9.7300000000000004" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_h1_b2]" value="2.3500000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kdp_net]" value="0.106" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kdp_net_14]" value="0.0066299999999999996" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kdp_net_px]" value="83.299999999999997" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kp_net]" value="0.55600000000000005" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kp_net_b2]" value="1.5" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kp_net_en]" value="6.8799999999999999" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kp_net_15]" value="0.0088100000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ka_px]" value="0.055" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ki_px]" value="0.11899999999999999" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ki_px_p1]" value="6.6900000000000004" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_pds]" value="0.046699999999999998" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_pds]" value="0.0144" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_pds_20]" value="3.04" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ka_15]" value="0.70899999999999996" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ka_15_14]" value="7.3799999999999999" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ki_15]" value="0.89400000000000002" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ki_15_b2]" value="2.1600000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ka_tem]" value="0.0848" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ka_tem_lo]" value="3.8399999999999999" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ka_tem_p1]" value="0.063799999999999996" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ki_tem]" value="0.32300000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ki_tem_px]" value="1.9199999999999999" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_lo]" value="0.044999999999999998" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_lo_m1]" value="0.011299999999999999" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_lo]" value="0.0048300000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_lo_h1]" value="0.13900000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ka_lo]" value="0.023199999999999998" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ka_lo_b2]" value="1.1100000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ki_lo]" value="0.96499999999999997" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kas_net]" value="5.6100000000000003" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[WHI5T]" value="2.1000000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[SBFT]" value="0.46800000000000003" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[MCM1T]" value="0.28199999999999997" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[APCPT]" value="45.700000000000003" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[CDH1T]" value="0.80800000000000005" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[NET1T]" value="6.4000000000000004" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[CDC14T]" value="6.2300000000000004" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[PPXT]" value="0.86599999999999999" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ESP1T]" value="0.26400000000000001" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[CDC15T]" value="1.02" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[TEM1T]" value="1.29" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_pds_20_i]" value="0.125" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[f]" value="0.40000000000000002" type="ModelValue" simulationType="fixed"/>
          <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[phi_28]" value="0" type="ModelValue" simulationType="fixed"/>
        </ModelParameterGroup>
        <ModelParameterGroup cn="String=Kinetic Parameters" type="Group">
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Growth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Growth],ParameterGroup=Parameters,Parameter=mu" value="0.0077016353395549476" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[mu],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Cln3 Synth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Cln3 Synth],ParameterGroup=Parameters,Parameter=Dn3" value="0.73199999999999998" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[Dn3],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Cln3 Synth],ParameterGroup=Parameters,Parameter=Jn3" value="4.2699999999999996" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[Jn3],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Cln3 Synth],ParameterGroup=Parameters,Parameter=ks_n3" value="1.1100000000000001" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_n3],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Cln3 Degr]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Cln3 Degr],ParameterGroup=Parameters,Parameter=k1" value="0.79400000000000004" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_n3],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Bck2 Synth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Bck2 Synth],ParameterGroup=Parameters,Parameter=ks_k2" value="0.055300000000000002" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_k2],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Bck2 Degr]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Bck2 Degr],ParameterGroup=Parameters,Parameter=k1" value="3.0099999999999998" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_k2],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[WHI5deP Synth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[WHI5deP Synth],ParameterGroup=Parameters,Parameter=WHI5T" value="2.1000000000000001" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[WHI5T],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[WHI5deP Synth],ParameterGroup=Parameters,Parameter=gamma" value="2.2200000000000002" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[gamma],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[WHI5deP Synth],ParameterGroup=Parameters,Parameter=kdp_i5" value="1.22" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kdp_i5],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[WHI5deP Synth],ParameterGroup=Parameters,Parameter=kdp_i5_14" value="0.19500000000000001" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kdp_i5_14],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[WHI5deP Synth],ParameterGroup=Parameters,Parameter=kp_i5" value="0.0275" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kp_i5],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[WHI5deP Synth],ParameterGroup=Parameters,Parameter=kp_i5_b5" value="0.042200000000000001" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kp_i5_b5],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[WHI5deP Synth],ParameterGroup=Parameters,Parameter=kp_i5_k2" value="23.699999999999999" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kp_i5_k2],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[WHI5deP Synth],ParameterGroup=Parameters,Parameter=kp_i5_n2" value="2.9700000000000002" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kp_i5_n2],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[WHI5deP Synth],ParameterGroup=Parameters,Parameter=kp_i5_n3" value="6.0999999999999996" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kp_i5_n3],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[WHI5deP Synth],ParameterGroup=Parameters,Parameter=sig" value="9.6300000000000008" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[sig],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[SBFdeP Synth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[SBFdeP Synth],ParameterGroup=Parameters,Parameter=SBFT" value="0.46800000000000003" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[SBFT],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[SBFdeP Synth],ParameterGroup=Parameters,Parameter=gamma" value="2.2200000000000002" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[gamma],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[SBFdeP Synth],ParameterGroup=Parameters,Parameter=kdp_bf" value="2.9300000000000002" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kdp_bf],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[SBFdeP Synth],ParameterGroup=Parameters,Parameter=kp_bf_b2" value="9.3599999999999994" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kp_bf_b2],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[SBFdeP Synth],ParameterGroup=Parameters,Parameter=sig" value="9.6300000000000008" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[sig],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Cln2 Synth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Cln2 Synth],ParameterGroup=Parameters,Parameter=ks_n2" value="1e-08" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_n2],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Cln2 Synth],ParameterGroup=Parameters,Parameter=ks_n2_bf" value="0.996" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_n2_bf],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Cln2 Degr]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Cln2 Degr],ParameterGroup=Parameters,Parameter=k1" value="0.032000000000000001" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_n2],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CKIT Synth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CKIT Synth],ParameterGroup=Parameters,Parameter=ks_ki" value="0.0066299999999999996" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_ki],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CKIT Synth],ParameterGroup=Parameters,Parameter=ks_ki_swi5" value="0.088999999999999996" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_ki_swi5],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CKIT Degr]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CKIT Degr],ParameterGroup=Parameters,Parameter=kd_ki" value="0.052400000000000002" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_ki],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CKIT Degr],ParameterGroup=Parameters,Parameter=kd_kip" value="0.89900000000000002" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_kip],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CKIP Synth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CKIP Synth],ParameterGroup=Parameters,Parameter=e_ki_b2" value="3.1200000000000001" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_ki_b2],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CKIP Synth],ParameterGroup=Parameters,Parameter=e_ki_b5" value="2.3900000000000001" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_ki_b5],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CKIP Synth],ParameterGroup=Parameters,Parameter=e_ki_k2" value="0.39700000000000002" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_ki_k2],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CKIP Synth],ParameterGroup=Parameters,Parameter=e_ki_n2" value="19.5" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_ki_n2],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CKIP Synth],ParameterGroup=Parameters,Parameter=e_ki_n3" value="1.05" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_ki_n3],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CKIP Synth],ParameterGroup=Parameters,Parameter=gammaki" value="12.9" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[gammaki],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CKIP Synth],ParameterGroup=Parameters,Parameter=kd_kip" value="0.89900000000000002" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_kip],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CKIP Synth],ParameterGroup=Parameters,Parameter=kdp_ki" value="0.83599999999999997" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kdp_ki],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CKIP Synth],ParameterGroup=Parameters,Parameter=kdp_ki_14" value="1.1100000000000001" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kdp_ki_14],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CKIP Synth],ParameterGroup=Parameters,Parameter=kp_ki_e" value="0.65000000000000002" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kp_ki_e],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CKIP Synth],ParameterGroup=Parameters,Parameter=sig" value="9.6300000000000008" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[sig],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Clb5T Synth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Clb5T Synth],ParameterGroup=Parameters,Parameter=ks_b5" value="0.00053799999999999996" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_b5],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Clb5T Synth],ParameterGroup=Parameters,Parameter=ks_b5_bf" value="0.0178" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_b5_bf],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Clb5T Degr]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Clb5T Degr],ParameterGroup=Parameters,Parameter=kd_b5" value="0.055599999999999997" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_b5],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Clb5T Degr],ParameterGroup=Parameters,Parameter=kd_b5_20" value="0.044499999999999998" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_b5_20],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Clb5T Degr],ParameterGroup=Parameters,Parameter=kd_b5_20_i" value="0.0049800000000000001" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_b5_20_i],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Clb2T Synth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Clb2T Synth],ParameterGroup=Parameters,Parameter=ks_b2" value="0.00762" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_b2],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Clb2T Synth],ParameterGroup=Parameters,Parameter=ks_b2_m1" value="0.031" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_b2_m1],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Clb2T Degr]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Clb2T Degr],ParameterGroup=Parameters,Parameter=kd_b2" value="0.00298" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_b2],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Clb2T Degr],ParameterGroup=Parameters,Parameter=kd_b2_20" value="0.13600000000000001" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_b2_20],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Clb2T Degr],ParameterGroup=Parameters,Parameter=kd_b2_20_i" value="0.037400000000000003" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_b2_20_i],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[Clb2T Degr],ParameterGroup=Parameters,Parameter=kd_b2_h1" value="0.66200000000000003" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_b2_h1],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[BUD Synth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[BUD Synth],ParameterGroup=Parameters,Parameter=e_bud_b2" value="1.8899999999999999" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_bud_b2],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[BUD Synth],ParameterGroup=Parameters,Parameter=e_bud_b5" value="3" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_bud_b5],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[BUD Synth],ParameterGroup=Parameters,Parameter=e_bud_n2" value="1.1200000000000001" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_bud_n2],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[BUD Synth],ParameterGroup=Parameters,Parameter=e_bud_n3" value="0.0077999999999999996" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_bud_n3],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[BUD Synth],ParameterGroup=Parameters,Parameter=ks_bud_e" value="0.28699999999999998" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_bud_e],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[BUD Degr]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[BUD Degr],ParameterGroup=Parameters,Parameter=k1" value="0.058999999999999997" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_bud],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[ORI Synth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[ORI Synth],ParameterGroup=Parameters,Parameter=e_ori_b2" value="0.124" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_ori_b2],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[ORI Synth],ParameterGroup=Parameters,Parameter=e_ori_b5" value="5.04" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_ori_b5],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[ORI Synth],ParameterGroup=Parameters,Parameter=ks_ori_e" value="1.8999999999999999" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_ori_e],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[ORI Degr]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[ORI Degr],ParameterGroup=Parameters,Parameter=k1" value="0.081699999999999995" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_ori],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[SPN Synth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[SPN Synth],ParameterGroup=Parameters,Parameter=Jspn" value="0.80900000000000005" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[Jspn],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[SPN Synth],ParameterGroup=Parameters,Parameter=ks_spn" value="0.074300000000000005" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_spn],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[SPN Degr]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[SPN Degr],ParameterGroup=Parameters,Parameter=k1" value="0.038399999999999997" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_spn],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[SWI5T Synth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[SWI5T Synth],ParameterGroup=Parameters,Parameter=ks_swi5" value="0.0055799999999999999" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_swi5],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[SWI5T Synth],ParameterGroup=Parameters,Parameter=ks_swi5_m1" value="0.038899999999999997" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_swi5_m1],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[SWI5T Degr]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[SWI5T Degr],ParameterGroup=Parameters,Parameter=k1" value="0.042000000000000003" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_swi5],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDC20T Synth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDC20T Synth],ParameterGroup=Parameters,Parameter=ks_20" value="0.022100000000000002" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_20],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDC20T Synth],ParameterGroup=Parameters,Parameter=ks_20_m1" value="0.35399999999999998" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_20_m1],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDC20T Degr]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDC20T Degr],ParameterGroup=Parameters,Parameter=k1" value="0.124" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_20],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDC20A_APCP Synth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDC20A_APCP Synth],ParameterGroup=Parameters,Parameter=gamma" value="2.2200000000000002" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[gamma],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDC20A_APCP Synth],ParameterGroup=Parameters,Parameter=ka_20" value="0.0104" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ka_20],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDC20A_APCP Synth],ParameterGroup=Parameters,Parameter=kd_20" value="0.124" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_20],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDC20A_APCP Synth],ParameterGroup=Parameters,Parameter=ki_20_ori" value="5.04" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ki_20_ori],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDC20A_APCP Synth],ParameterGroup=Parameters,Parameter=sig" value="9.6300000000000008" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[sig],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[APCP Synth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[APCP Synth],ParameterGroup=Parameters,Parameter=APCPT" value="45.700000000000003" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[APCPT],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[APCP Synth],ParameterGroup=Parameters,Parameter=gammacp" value="1.3400000000000001" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[gammacp],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[APCP Synth],ParameterGroup=Parameters,Parameter=ka_cp_b2" value="0.33400000000000002" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ka_cp_b2],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[APCP Synth],ParameterGroup=Parameters,Parameter=ki_cp" value="0.20999999999999999" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ki_cp],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[APCP Synth],ParameterGroup=Parameters,Parameter=sig" value="9.6300000000000008" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[sig],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDH1A Synth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDH1A Synth],ParameterGroup=Parameters,Parameter=CDH1T" value="0.80800000000000005" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[CDH1T],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDH1A Synth],ParameterGroup=Parameters,Parameter=e_h1_b2" value="2.3500000000000001" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_h1_b2],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDH1A Synth],ParameterGroup=Parameters,Parameter=e_h1_b5" value="9.7300000000000004" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_h1_b5],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDH1A Synth],ParameterGroup=Parameters,Parameter=e_h1_n2" value="1.5600000000000001" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_h1_n2],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDH1A Synth],ParameterGroup=Parameters,Parameter=e_h1_n3" value="3.75" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[e_h1_n3],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDH1A Synth],ParameterGroup=Parameters,Parameter=gamma" value="2.2200000000000002" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[gamma],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDH1A Synth],ParameterGroup=Parameters,Parameter=ka_h1" value="0.24099999999999999" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ka_h1],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDH1A Synth],ParameterGroup=Parameters,Parameter=ka_h1_14" value="32.200000000000003" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ka_h1_14],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDH1A Synth],ParameterGroup=Parameters,Parameter=ki_h1" value="0.14399999999999999" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ki_h1],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDH1A Synth],ParameterGroup=Parameters,Parameter=ki_h1_e" value="0.215" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ki_h1_e],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDH1A Synth],ParameterGroup=Parameters,Parameter=sig" value="9.6300000000000008" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[sig],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[NET1deP Synth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[NET1deP Synth],ParameterGroup=Parameters,Parameter=NET1T" value="6.4000000000000004" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[NET1T],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[NET1deP Synth],ParameterGroup=Parameters,Parameter=gamma" value="2.2200000000000002" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[gamma],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[NET1deP Synth],ParameterGroup=Parameters,Parameter=kdp_net" value="0.106" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kdp_net],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[NET1deP Synth],ParameterGroup=Parameters,Parameter=kdp_net_14" value="0.0066299999999999996" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kdp_net_14],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[NET1deP Synth],ParameterGroup=Parameters,Parameter=kdp_net_px" value="83.299999999999997" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kdp_net_px],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[NET1deP Synth],ParameterGroup=Parameters,Parameter=kp_net" value="0.55600000000000005" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kp_net],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[NET1deP Synth],ParameterGroup=Parameters,Parameter=kp_net_15" value="0.0088100000000000001" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kp_net_15],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[NET1deP Synth],ParameterGroup=Parameters,Parameter=kp_net_b2" value="1.5" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kp_net_b2],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[NET1deP Synth],ParameterGroup=Parameters,Parameter=kp_net_en" value="6.8799999999999999" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kp_net_en],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[NET1deP Synth],ParameterGroup=Parameters,Parameter=signet" value="1.52" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[signet],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[PPX Synth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[PPX Synth],ParameterGroup=Parameters,Parameter=PPXT" value="0.86599999999999999" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[PPXT],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[PPX Synth],ParameterGroup=Parameters,Parameter=gamma" value="2.2200000000000002" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[gamma],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[PPX Synth],ParameterGroup=Parameters,Parameter=ka_px" value="0.055" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ka_px],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[PPX Synth],ParameterGroup=Parameters,Parameter=ki_px" value="0.11899999999999999" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ki_px],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[PPX Synth],ParameterGroup=Parameters,Parameter=ki_px_p1" value="6.6900000000000004" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ki_px_p1],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[PPX Synth],ParameterGroup=Parameters,Parameter=sig" value="9.6300000000000008" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[sig],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[PDS1T Synth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[PDS1T Synth],ParameterGroup=Parameters,Parameter=v" value="0.046699999999999998" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ks_pds],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[PDS1T Degr]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[PDS1T Degr],ParameterGroup=Parameters,Parameter=kd_pds" value="0.0144" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_pds],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[PDS1T Degr],ParameterGroup=Parameters,Parameter=kd_pds_20_i" value="0.125" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_pds_20_i],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[PDS1T Degr],ParameterGroup=Parameters,Parameter=ks_pds_20" value="3.04" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[kd_pds_20],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDC15 Synth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDC15 Synth],ParameterGroup=Parameters,Parameter=CDC15T" value="1.02" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[CDC15T],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDC15 Synth],ParameterGroup=Parameters,Parameter=gamma" value="2.2200000000000002" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[gamma],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDC15 Synth],ParameterGroup=Parameters,Parameter=ka_15" value="0.70899999999999996" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ka_15],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDC15 Synth],ParameterGroup=Parameters,Parameter=ka_15_14" value="7.3799999999999999" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ka_15_14],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDC15 Synth],ParameterGroup=Parameters,Parameter=ki_15" value="0.89400000000000002" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ki_15],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDC15 Synth],ParameterGroup=Parameters,Parameter=ki_15_b2" value="2.1600000000000001" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ki_15_b2],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[CDC15 Synth],ParameterGroup=Parameters,Parameter=sig" value="9.6300000000000008" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[sig],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
          </ModelParameterGroup>
          <ModelParameterGroup cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[TEM1 Synth]" type="Reaction">
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[TEM1 Synth],ParameterGroup=Parameters,Parameter=TEM1T" value="1.29" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[TEM1T],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[TEM1 Synth],ParameterGroup=Parameters,Parameter=gammatem" value="0.36899999999999999" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[gammatem],Reference=InitialValue>
              </InitialExpression>
            </ModelParameter>
            <ModelParameter cn="CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Reactions[TEM1 Synth],ParameterGroup=Parameters,Parameter=ka_tem" value="0.0848" type="ReactionParameter" simulationType="assignment">
              <InitialExpression>
                &lt;CN=Root,Model=Yeast Cell Cycle_1_1,Vector=Values[ka_tem],Reference=InitialValue>
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        <ParameterGroup name="OptimizationConstraintList">
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        <Parameter name="Time-Course" type="cn" value="CN=Root,Vector=TaskList[Time-Course]"/>
        <Parameter name="Create Parameter Sets" type="bool" value="0"/>
        <ParameterGroup name="Experiment Set">
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        <ParameterGroup name="Validation Set">
          <Parameter name="Threshold" type="unsignedInteger" value="5"/>
          <Parameter name="Weight" type="unsignedFloat" value="1"/>
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      <Method name="Evolutionary Programming" type="EvolutionaryProgram">
        <Parameter name="Number of Generations" type="unsignedInteger" value="200"/>
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        <Parameter name="Steady-State" type="key" value="Task_27"/>
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      <Method name="MCA Method (Reder)" type="MCAMethod(Reder)">
        <Parameter name="Modulation Factor" type="unsignedFloat" value="1.0000000000000001e-09"/>
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        <Parameter name="Use Smallbone" type="bool" value="1"/>
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        <Parameter name="ExponentNumber" type="unsignedInteger" value="3"/>
        <Parameter name="DivergenceRequested" type="bool" value="1"/>
        <Parameter name="TransientTime" type="float" value="0"/>
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      <Method name="Wolf Method" type="WolfMethod">
        <Parameter name="Orthonormalization Interval" type="unsignedFloat" value="1"/>
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      </Method>
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        <Parameter name="StepNumber" type="unsignedInteger" value="100"/>
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        <Parameter name="Duration" type="float" value="1"/>
        <Parameter name="TimeSeriesRequested" type="bool" value="1"/>
        <Parameter name="OutputStartTime" type="float" value="0"/>
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        <Parameter name="Deuflhard Tolerance" type="unsignedFloat" value="0.0001"/>
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    <Task key="Task_23" name="Sensitivities" type="sensitivities" scheduled="false" updateModel="false">
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        <ParameterGroup name="TargetFunctions">
          <Parameter name="SingleObject" type="cn" value=""/>
          <Parameter name="ObjectListType" type="unsignedInteger" value="7"/>
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        <ParameterGroup name="ListOfVariables">
          <ParameterGroup name="Variables">
            <Parameter name="SingleObject" type="cn" value=""/>
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          <ParameterGroup name="Variables">
            <Parameter name="SingleObject" type="cn" value=""/>
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      </Problem>
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    <SBMLMap SBMLid="Rate_Law_for_SPN_Synth_1" COPASIkey="Function_87"/>
    <SBMLMap SBMLid="Rate_Law_for_SWI5T_Synth_1" COPASIkey="Function_88"/>
    <SBMLMap SBMLid="Rate_Law_for_TEM1_Synth_1" COPASIkey="Function_97"/>
    <SBMLMap SBMLid="Rate_Law_for_WHI5deP_Synth_1" COPASIkey="Function_75"/>
    <SBMLMap SBMLid="SBF" COPASIkey="Metabolite_52"/>
    <SBMLMap SBMLid="SBFT" COPASIkey="ModelValue_138"/>
    <SBMLMap SBMLid="SBFdeP" COPASIkey="Metabolite_77"/>
    <SBMLMap SBMLid="SBFdeP_Synth" COPASIkey="Reaction_71"/>
    <SBMLMap SBMLid="SPN" COPASIkey="Metabolite_69"/>
    <SBMLMap SBMLid="SPN_Degr" COPASIkey="Reaction_56"/>
    <SBMLMap SBMLid="SPN_Synth" COPASIkey="Reaction_57"/>
    <SBMLMap SBMLid="SPN_completion" COPASIkey="Event_7"/>
    <SBMLMap SBMLid="SWI5A" COPASIkey="Metabolite_47"/>
    <SBMLMap SBMLid="SWI5T" COPASIkey="Metabolite_68"/>
    <SBMLMap SBMLid="SWI5T_Degr" COPASIkey="Reaction_54"/>
    <SBMLMap SBMLid="SWI5T_Synth" COPASIkey="Reaction_55"/>
    <SBMLMap SBMLid="SWI5T_peaks" COPASIkey="Metabolite_102"/>
    <SBMLMap SBMLid="Sigmoid" COPASIkey="Function_46"/>
    <SBMLMap SBMLid="Swi5T_peak" COPASIkey="Event_12"/>
    <SBMLMap SBMLid="TEM1" COPASIkey="Metabolite_59"/>
    <SBMLMap SBMLid="TEM1T" COPASIkey="ModelValue_129"/>
    <SBMLMap SBMLid="TEM1_Synth" COPASIkey="Reaction_43"/>
    <SBMLMap SBMLid="V" COPASIkey="Metabolite_81"/>
    <SBMLMap SBMLid="VDiv1" COPASIkey="Metabolite_107"/>
    <SBMLMap SBMLid="VDiv2" COPASIkey="Metabolite_108"/>
    <SBMLMap SBMLid="VDiv3" COPASIkey="Metabolite_109"/>
    <SBMLMap SBMLid="WHI5T" COPASIkey="ModelValue_139"/>
    <SBMLMap SBMLid="WHI5deP" COPASIkey="Metabolite_78"/>
    <SBMLMap SBMLid="WHI5deP_Synth" COPASIkey="Reaction_72"/>
    <SBMLMap SBMLid="cell" COPASIkey="Compartment_1"/>
    <SBMLMap SBMLid="dBCK2" COPASIkey="Metabolite_87"/>
    <SBMLMap SBMLid="dCDC20T" COPASIkey="Metabolite_93"/>
    <SBMLMap SBMLid="dCKIT" COPASIkey="Metabolite_89"/>
    <SBMLMap SBMLid="dCLB2T" COPASIkey="Metabolite_91"/>
    <SBMLMap SBMLid="dCLB5T" COPASIkey="Metabolite_90"/>
    <SBMLMap SBMLid="dCLN2" COPASIkey="Metabolite_88"/>
    <SBMLMap SBMLid="dCLN3" COPASIkey="Metabolite_86"/>
    <SBMLMap SBMLid="dPDS1T" COPASIkey="Metabolite_94"/>
    <SBMLMap SBMLid="dPOLOT" COPASIkey="Metabolite_95"/>
    <SBMLMap SBMLid="dSWI5T" COPASIkey="Metabolite_92"/>
    <SBMLMap SBMLid="e_bud_b2" COPASIkey="ModelValue_202"/>
    <SBMLMap SBMLid="e_bud_b5" COPASIkey="ModelValue_203"/>
    <SBMLMap SBMLid="e_bud_n2" COPASIkey="ModelValue_204"/>
    <SBMLMap SBMLid="e_bud_n3" COPASIkey="ModelValue_205"/>
    <SBMLMap SBMLid="e_h1_b2" COPASIkey="ModelValue_170"/>
    <SBMLMap SBMLid="e_h1_b5" COPASIkey="ModelValue_171"/>
    <SBMLMap SBMLid="e_h1_n2" COPASIkey="ModelValue_172"/>
    <SBMLMap SBMLid="e_h1_n3" COPASIkey="ModelValue_173"/>
    <SBMLMap SBMLid="e_ki_b2" COPASIkey="ModelValue_218"/>
    <SBMLMap SBMLid="e_ki_b5" COPASIkey="ModelValue_219"/>
    <SBMLMap SBMLid="e_ki_k2" COPASIkey="ModelValue_221"/>
    <SBMLMap SBMLid="e_ki_n2" COPASIkey="ModelValue_220"/>
    <SBMLMap SBMLid="e_ki_n3" COPASIkey="ModelValue_222"/>
    <SBMLMap SBMLid="e_ori_b2" COPASIkey="ModelValue_195"/>
    <SBMLMap SBMLid="e_ori_b5" COPASIkey="ModelValue_196"/>
    <SBMLMap SBMLid="f" COPASIkey="ModelValue_127"/>
    <SBMLMap SBMLid="gamma" COPASIkey="ModelValue_247"/>
    <SBMLMap SBMLid="gammacp" COPASIkey="ModelValue_245"/>
    <SBMLMap SBMLid="gammaki" COPASIkey="ModelValue_246"/>
    <SBMLMap SBMLid="gammatem" COPASIkey="ModelValue_244"/>
    <SBMLMap SBMLid="ka_15" COPASIkey="ModelValue_156"/>
    <SBMLMap SBMLid="ka_15_14" COPASIkey="ModelValue_155"/>
    <SBMLMap SBMLid="ka_20" COPASIkey="ModelValue_183"/>
    <SBMLMap SBMLid="ka_cp_b2" COPASIkey="ModelValue_179"/>
    <SBMLMap SBMLid="ka_h1" COPASIkey="ModelValue_177"/>
    <SBMLMap SBMLid="ka_h1_14" COPASIkey="ModelValue_176"/>
    <SBMLMap SBMLid="ka_lo" COPASIkey="ModelValue_143"/>
    <SBMLMap SBMLid="ka_lo_b2" COPASIkey="ModelValue_142"/>
    <SBMLMap SBMLid="ka_m1_b2" COPASIkey="ModelValue_188"/>
    <SBMLMap SBMLid="ka_px" COPASIkey="ModelValue_162"/>
    <SBMLMap SBMLid="ka_swi5_14" COPASIkey="ModelValue_190"/>
    <SBMLMap SBMLid="ka_tem" COPASIkey="ModelValue_152"/>
    <SBMLMap SBMLid="ka_tem_lo" COPASIkey="ModelValue_151"/>
    <SBMLMap SBMLid="ka_tem_p1" COPASIkey="ModelValue_150"/>
    <SBMLMap SBMLid="kas_net" COPASIkey="ModelValue_140"/>
    <SBMLMap SBMLid="kd_20" COPASIkey="ModelValue_184"/>
    <SBMLMap SBMLid="kd_b2" COPASIkey="ModelValue_209"/>
    <SBMLMap SBMLid="kd_b2_20" COPASIkey="ModelValue_208"/>
    <SBMLMap SBMLid="kd_b2_20_i" COPASIkey="ModelValue_181"/>
    <SBMLMap SBMLid="kd_b2_h1" COPASIkey="ModelValue_207"/>
    <SBMLMap SBMLid="kd_b5" COPASIkey="ModelValue_213"/>
    <SBMLMap SBMLid="kd_b5_20" COPASIkey="ModelValue_212"/>
    <SBMLMap SBMLid="kd_b5_20_i" COPASIkey="ModelValue_182"/>
    <SBMLMap SBMLid="kd_bud" COPASIkey="ModelValue_201"/>
    <SBMLMap SBMLid="kd_k2" COPASIkey="ModelValue_240"/>
    <SBMLMap SBMLid="kd_ki" COPASIkey="ModelValue_225"/>
    <SBMLMap SBMLid="kd_kip" COPASIkey="ModelValue_224"/>
    <SBMLMap SBMLid="kd_lo" COPASIkey="ModelValue_145"/>
    <SBMLMap SBMLid="kd_lo_h1" COPASIkey="ModelValue_144"/>
    <SBMLMap SBMLid="kd_n2" COPASIkey="ModelValue_228"/>
    <SBMLMap SBMLid="kd_n3" COPASIkey="ModelValue_248"/>
    <SBMLMap SBMLid="kd_ori" COPASIkey="ModelValue_194"/>
    <SBMLMap SBMLid="kd_pds" COPASIkey="ModelValue_158"/>
    <SBMLMap SBMLid="kd_pds_20_i" COPASIkey="ModelValue_128"/>
    <SBMLMap SBMLid="kd_spn" COPASIkey="ModelValue_199"/>
    <SBMLMap SBMLid="kd_swi5" COPASIkey="ModelValue_191"/>
    <SBMLMap SBMLid="kdp_bf" COPASIkey="ModelValue_232"/>
    <SBMLMap SBMLid="kdp_i5" COPASIkey="ModelValue_239"/>
    <SBMLMap SBMLid="kdp_i5_14" COPASIkey="ModelValue_238"/>
    <SBMLMap SBMLid="kdp_ki" COPASIkey="ModelValue_217"/>
    <SBMLMap SBMLid="kdp_ki_14" COPASIkey="ModelValue_216"/>
    <SBMLMap SBMLid="kdp_net" COPASIkey="ModelValue_169"/>
    <SBMLMap SBMLid="kdp_net_14" COPASIkey="ModelValue_168"/>
    <SBMLMap SBMLid="kdp_net_px" COPASIkey="ModelValue_167"/>
    <SBMLMap SBMLid="ki_15" COPASIkey="ModelValue_154"/>
    <SBMLMap SBMLid="ki_15_b2" COPASIkey="ModelValue_153"/>
    <SBMLMap SBMLid="ki_20_ori" COPASIkey="ModelValue_180"/>
    <SBMLMap SBMLid="ki_cp" COPASIkey="ModelValue_178"/>
    <SBMLMap SBMLid="ki_h1" COPASIkey="ModelValue_175"/>
    <SBMLMap SBMLid="ki_h1_e" COPASIkey="ModelValue_174"/>
    <SBMLMap SBMLid="ki_lo" COPASIkey="ModelValue_141"/>
    <SBMLMap SBMLid="ki_m1" COPASIkey="ModelValue_187"/>
    <SBMLMap SBMLid="ki_px" COPASIkey="ModelValue_161"/>
    <SBMLMap SBMLid="ki_px_p1" COPASIkey="ModelValue_160"/>
    <SBMLMap SBMLid="ki_swi5_b2" COPASIkey="ModelValue_189"/>
    <SBMLMap SBMLid="ki_tem" COPASIkey="ModelValue_149"/>
    <SBMLMap SBMLid="ki_tem_px" COPASIkey="ModelValue_148"/>
    <SBMLMap SBMLid="kp_bf_b2" COPASIkey="ModelValue_231"/>
    <SBMLMap SBMLid="kp_i5" COPASIkey="ModelValue_237"/>
    <SBMLMap SBMLid="kp_i5_b5" COPASIkey="ModelValue_233"/>
    <SBMLMap SBMLid="kp_i5_k2" COPASIkey="ModelValue_235"/>
    <SBMLMap SBMLid="kp_i5_n2" COPASIkey="ModelValue_234"/>
    <SBMLMap SBMLid="kp_i5_n3" COPASIkey="ModelValue_236"/>
    <SBMLMap SBMLid="kp_ki_e" COPASIkey="ModelValue_223"/>
    <SBMLMap SBMLid="kp_net" COPASIkey="ModelValue_166"/>
    <SBMLMap SBMLid="kp_net_15" COPASIkey="ModelValue_163"/>
    <SBMLMap SBMLid="kp_net_b2" COPASIkey="ModelValue_165"/>
    <SBMLMap SBMLid="kp_net_en" COPASIkey="ModelValue_164"/>
    <SBMLMap SBMLid="ks_20" COPASIkey="ModelValue_186"/>
    <SBMLMap SBMLid="ks_20_m1" COPASIkey="ModelValue_185"/>
    <SBMLMap SBMLid="ks_b2" COPASIkey="ModelValue_211"/>
    <SBMLMap SBMLid="ks_b2_m1" COPASIkey="ModelValue_210"/>
    <SBMLMap SBMLid="ks_b5" COPASIkey="ModelValue_215"/>
    <SBMLMap SBMLid="ks_b5_bf" COPASIkey="ModelValue_214"/>
    <SBMLMap SBMLid="ks_bud_e" COPASIkey="ModelValue_206"/>
    <SBMLMap SBMLid="ks_k2" COPASIkey="ModelValue_241"/>
    <SBMLMap SBMLid="ks_ki" COPASIkey="ModelValue_227"/>
    <SBMLMap SBMLid="ks_ki_swi5" COPASIkey="ModelValue_226"/>
    <SBMLMap SBMLid="ks_lo" COPASIkey="ModelValue_147"/>
    <SBMLMap SBMLid="ks_lo_m1" COPASIkey="ModelValue_146"/>
    <SBMLMap SBMLid="ks_n2" COPASIkey="ModelValue_230"/>
    <SBMLMap SBMLid="ks_n2_bf" COPASIkey="ModelValue_229"/>
    <SBMLMap SBMLid="ks_n3" COPASIkey="ModelValue_251"/>
    <SBMLMap SBMLid="ks_ori_e" COPASIkey="ModelValue_197"/>
    <SBMLMap SBMLid="ks_pds" COPASIkey="ModelValue_159"/>
    <SBMLMap SBMLid="ks_pds_20" COPASIkey="ModelValue_157"/>
    <SBMLMap SBMLid="ks_spn" COPASIkey="ModelValue_200"/>
    <SBMLMap SBMLid="ks_swi5" COPASIkey="ModelValue_193"/>
    <SBMLMap SBMLid="ks_swi5_m1" COPASIkey="ModelValue_192"/>
    <SBMLMap SBMLid="mdt" COPASIkey="ModelValue_253"/>
    <SBMLMap SBMLid="mu" COPASIkey="ModelValue_252"/>
    <SBMLMap SBMLid="sig" COPASIkey="ModelValue_243"/>
    <SBMLMap SBMLid="signet" COPASIkey="ModelValue_242"/>
  </SBMLReference>
  <ListOfUnitDefinitions>
    <UnitDefinition key="Unit_0" name="meter" symbol="m">
      <Expression>
        m
      </Expression>
    </UnitDefinition>
    <UnitDefinition key="Unit_2" name="second" symbol="s">
      <Expression>
        s
      </Expression>
    </UnitDefinition>
    <UnitDefinition key="Unit_6" name="Avogadro" symbol="Avogadro">
      <Expression>
        Avogadro
      </Expression>
    </UnitDefinition>
    <UnitDefinition key="Unit_8" name="item" symbol="#">
      <Expression>
        #
      </Expression>
    </UnitDefinition>
  </ListOfUnitDefinitions>
</COPASI>
