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RCR_SP_70K_SMILES-MMChat

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OpenMol 3

{ "selfies": [ "[C][I]", "[O][=C][Branch1][C][O][C][Branch1][C][O][C][=C][C][=C][C][=Branch1][Ring2][=C][Ring1][=Branch1][N][C][=N][C][=C][N][=C][Ring1][=Branch1][S][Ring1][O]", "[C][O][C][=Branch1][C][=O][C][Branch1][C][O][C][=C][C][=C][C][=Branch1][Ring2][=C][Ring1][=Branch1][N][C][=N][C][=C][N][=C][Ring1][=Branch1][S][Ring1][O]" ], "smiles": [ "CI", "O=C(O)C(O)c1ccc2c(c1)Nc1nccnc1S2", "COC(=O)C(O)c1ccc2c(c1)Nc1nccnc1S2" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Please suggest some possible solvents that could have been used in the following chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>.", "role": "user" }, { "content": "CN(C)C=O .", "role": "assistant" } ]

{ "selfies": [ "[C][C][Branch1][C][C][Branch1][C][C][O][C][=Branch1][C][=O][N][C][C][N][C][C][Ring1][=Branch1]", "[O][=C][Branch1][C][O][C][C][C][N][Branch1][#C][C][=Branch1][C][=O][O][C][C][=C][C][=C][C][=C][Ring1][=Branch1][C][C][Ring1][S]", "[C][C][Branch1][C][C][Branch1][C][C][O][C][=Branch1][C][=O][N][C][C][N][Branch2][Ring1][=N][C][=Branch1][C][=O][C][C][C][N][Branch1][#C][C][=Branch1][C][=O][O][C][C][=C][C][=C][C][=C][Ring1][=Branch1][C][C][Ring1][S][C][C][Ring2][Ring1][Branch2]" ], "smiles": [ "CC(C)(C)OC(=O)N1CCNCC1", "O=C(O)C1CCN(C(=O)OCc2ccccc2)CC1", "CC(C)(C)OC(=O)N1CCN(C(=O)C2CCN(C(=O)OCc3ccccc3)CC2)CC1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Please suggest some possible solvents that could have been used in the following chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>.", "role": "user" }, { "content": "C1CCOC1.ClCCl .", "role": "assistant" } ]

{ "selfies": [ "[C][C][Branch1][C][C][Branch1][C][C][O][C][=Branch1][C][=O][N][C][C][N][Branch1][#C][C][=C][C][=C][Branch1][Branch1][C][#C][C][O][C][=C][Ring1][#Branch2][C][C][Ring1][S]", "[C][C][Branch1][C][C][Branch1][C][C][O][C][=Branch1][C][=O][N][C][C][N][Branch1][#C][C][=C][C][=C][Branch1][Branch1][C][C][C][O][C][=C][Ring1][#Branch2][C][C][Ring1][S]" ], "smiles": [ "CC(C)(C)OC(=O)N1CCN(c2ccc(C#CCO)cc2)CC1", "CC(C)(C)OC(=O)N1CCN(c2ccc(CCCO)cc2)CC1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Can you provide potential solvents for the following chemical reaction? <molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "CCO .", "role": "assistant" } ]

{ "selfies": [ "[C][C][=C][C][=C][Branch1][C][F][C][Branch1][C][Br][=N][Ring1][Branch2]", "[O][=C][Branch1][Ring1][O][O][C][=C][C][=C][C][Branch1][C][Cl][=C][Ring1][#Branch1]", "[C][C][=C][C][=C][Branch1][C][F][C][Branch1][C][Br][=N+1][Ring1][Branch2][O-1]" ], "smiles": [ "Cc1ccc(F)c(Br)n1", "O=C(OO)c1cccc(Cl)c1", "Cc1ccc(F)c(Br)[n+]1[O-]" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Based on the given chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>, suggest some possible solvents.", "role": "user" }, { "content": "The solvent can be ClC(Cl)Cl.O .", "role": "assistant" } ]

{ "selfies": [ "[C][O][C][=Branch1][C][=O][C][=Branch1][C][=O][C][=C][C][=C][C][=C][Ring1][=Branch1][C]", "[O][=C][C][C][C][=Branch1][C][=O][N][Ring1][=Branch1][Br]", "[C][O][C][=Branch1][C][=O][C][=Branch1][C][=O][C][=C][C][=C][C][=C][Ring1][=Branch1][C][Br]" ], "smiles": [ "COC(=O)C(=O)c1ccccc1C", "O=C1CCC(=O)N1Br", "COC(=O)C(=O)c1ccccc1CBr" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given the following chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>, what are some potential solvents that could have been employed?", "role": "user" }, { "content": "ClC(Cl)(Cl)Cl .", "role": "assistant" } ]

{ "selfies": [ "[C][C][C][C][=C][Branch2][Ring1][=Branch1][C][C][=C][C][=C][Branch1][O][C][=C][C][=C][C][=C][Ring1][=Branch1][C][#N][C][=C][Ring1][=C][C][=Branch1][C][=O][N][Branch1][Branch2][C][C][=C][S][C][=Ring1][Branch1][C][=N][C][=N][N][Ring2][Ring1][=C][Ring1][Branch1]", "[O][=C][Branch1][C][O-1][O]", "[NH3+1][O]", "[C][C][C][C][=C][Branch2][Ring1][S][C][C][=C][C][=C][Branch2][Ring1][Ring1][C][=C][C][=C][C][=C][Ring1][=Branch1][C][=N][O][C][=Branch1][C][=O][NH1][Ring1][=Branch1][C][=C][Ring2][Ring1][C][C][=Branch1][C][=O][N][Branch1][Branch2][C][C][=C][S][C][=Ring1][Branch1][C][=N][C][=N][N][Ring2][Ring2][C][Ring1][Branch1]" ], "smiles": [ "CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(-c2ccsc2)c2ncnn12", "O=C([O-])O", "[NH3+]O", "CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(-c2ccsc2)c2ncnn12" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Can you suggest some solvents that might have been used in the given chemical reaction? <molecule_2d>.<molecule_2d>.<molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "A probable solvent could be CCOC(C)=O .", "role": "assistant" } ]

{ "selfies": [ "[C][C][O][C][=Branch1][C][=O][C][=C][C][=C][N][=C][Branch1][#Branch2][C][C][=C][C][=C][C][=C][Ring1][=Branch1][N][Branch1][=C][C][C][=C][C][=C][Branch1][C][Cl][C][=C][Ring1][#Branch1][Cl][C][Ring2][Ring1][Branch1][=C][Ring2][Ring1][=Branch2]", "[O][=C][Branch1][C][O][C][=C][C][=C][N][=C][Branch1][#Branch2][C][C][=C][C][=C][C][=C][Ring1][=Branch1][N][Branch1][=C][C][C][=C][C][=C][Branch1][C][Cl][C][=C][Ring1][#Branch1][Cl][C][Ring2][Ring1][Branch1][=C][Ring2][Ring1][=Branch2]" ], "smiles": [ "CCOC(=O)c1ccc2nc(Cc3ccccc3)n(Cc3ccc(Cl)cc3Cl)c2c1", "O=C(O)c1ccc2nc(Cc3ccccc3)n(Cc3ccc(Cl)cc3Cl)c2c1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given the following chemical reaction <molecule_2d>>><molecule_2d>, what are some potential solvents that could have been employed?", "role": "user" }, { "content": "CCO .", "role": "assistant" } ]

{ "selfies": [ "[C][C][Branch1][C][C][Branch1][C][C][O][C][=Branch1][C][=O][N][C][C][C][Branch1][C][O][C][Ring1][=Branch1]", "[C][S][=Branch1][C][=O][=Branch1][C][=O][Cl]", "[C][C][Branch1][C][C][Branch1][C][C][O][C][=Branch1][C][=O][N][C][C][C][Branch1][#Branch2][O][S][Branch1][C][C][=Branch1][C][=O][=O][C][Ring1][#Branch2]" ], "smiles": [ "CC(C)(C)OC(=O)N1CCC(O)C1", "CS(=O)(=O)Cl", "CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)C1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Can you provide potential solvents for the following chemical reaction? <molecule_2d>.<molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "CCOC(C)=O.ClCCl .", "role": "assistant" } ]

{ "selfies": [ "[C][C][O][C][=Branch1][C][=O][C][O][C][=C][C][=C][Branch1][#Branch1][C][=Branch1][C][=O][C][Br][C][=C][Ring1][#Branch2][Br]", "[C][C][O][C][=Branch1][C][=O][C][O][C][=C][C][=C][Branch1][Ring2][C][C][Br][C][=C][Ring1][=Branch2][Br]" ], "smiles": [ "CCOC(=O)COc1ccc(C(=O)CBr)cc1Br", "CCOC(=O)COc1ccc(CCBr)cc1Br" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given the following reaction <molecule_2d>>><molecule_2d>, what are some possible solvents that could have been utilized?", "role": "user" }, { "content": "O=C(O)C(F)(F)F .", "role": "assistant" } ]

{ "selfies": [ "[C][C][Branch1][C][C][Branch1][C][C][O][C][=Branch1][C][=O][N][C][C][N][C][C][Ring1][=Branch1]", "[C][C][C][C][C][=N][C][=N][C][Branch1][C][Cl][=C][Ring1][#Branch1][Ring1][#Branch2]", "[C][C][C][C][C][=N][C][=N][C][Branch2][Ring1][Branch2][N][C][C][N][Branch1][=C][C][=Branch1][C][=O][O][C][Branch1][C][C][Branch1][C][C][C][C][C][Ring1][=N][=C][Ring2][Ring1][Ring1][Ring2][Ring1][=Branch1]" ], "smiles": [ "CC(C)(C)OC(=O)N1CCNCC1", "CC1CCc2ncnc(Cl)c21", "CC1CCc2ncnc(N3CCN(C(=O)OC(C)(C)C)CC3)c21" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Based on the given chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>, suggest some possible solvents.", "role": "user" }, { "content": "The solvent can be CCOC(C)=O.CN1CCCC1=O .", "role": "assistant" } ]

{ "selfies": [ "[C][C][Branch1][C][C][Branch1][C][C][Si][Branch1][C][C][Branch1][C][C][Cl]", "[C][C][O][P][=Branch1][C][=O][Branch1][#Branch2][C][O][C][C][Branch1][C][O][C][O][O][C][C]", "[C][C][O][P][=Branch1][C][=O][Branch2][Ring1][=Branch2][C][O][C][C][Branch1][C][O][C][O][Si][Branch1][C][C][Branch1][C][C][C][Branch1][C][C][Branch1][C][C][C][O][C][C]" ], "smiles": [ "CC(C)(C)[Si](C)(C)Cl", "CCOP(=O)(COCC(O)CO)OCC", "CCOP(=O)(COCC(O)CO[Si](C)(C)C(C)(C)C)OCC" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>.<molecule_2d>>><molecule_2d> Based on the given chemical reaction, can you propose some likely solvents that might have been utilized?", "role": "user" }, { "content": "A possible solvent can be ClCCl .", "role": "assistant" } ]

{ "selfies": [ "[C][S][C][C][C][N][C][=C][Branch2][Ring1][C][C][=Branch1][C][=O][N][C][C][=C][C][=C][Branch1][C][Cl][C][=C][Ring1][#Branch1][C][=Branch1][C][=O][C][=C][C][Branch1][#Branch2][C][N][C][C][O][C][C][Ring1][=Branch1][=C][C][=C][Ring1][=N][Ring2][Ring1][=N]", "[O][=C][Branch1][Ring1][O][O][C][=C][C][=C][C][Branch1][C][Cl][=C][Ring1][#Branch1]", "[C][S][=Branch1][C][=O][C][C][C][N][C][=C][Branch2][Ring1][C][C][=Branch1][C][=O][N][C][C][=C][C][=C][Branch1][C][Cl][C][=C][Ring1][#Branch1][C][=Branch1][C][=O][C][=C][C][Branch1][#Branch2][C][N][C][C][O][C][C][Ring1][=Branch1][=C][C][=C][Ring1][=N][Ring2][Ring1][=N]" ], "smiles": [ "CSCCCn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN3CCOCC3)ccc21", "O=C(OO)c1cccc(Cl)c1", "CS(=O)CCCn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN3CCOCC3)ccc21" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Can you provide potential solvents for the following chemical reaction? <molecule_2d>.<molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "ClCCl .", "role": "assistant" } ]

{ "selfies": [ "[C][O][C][=Branch1][C][=O][C][=C][C][=C][C][Branch2][Ring1][=Branch2][N][C][=Branch1][C][=O][N][C][=C][C][=C][Branch1][=Branch2][C][Branch1][C][C][Branch1][C][C][C][C][=C][Ring1][#Branch2][=C][Ring2][Ring1][Ring2]", "[C][C][Branch1][C][C][Branch1][C][C][C][=C][C][=C][Branch2][Ring1][=Branch1][N][C][=Branch1][C][=O][N][C][=C][C][=C][C][Branch1][=Branch1][C][=Branch1][C][=O][O][=C][Ring1][=Branch2][C][=C][Ring2][Ring1][Ring1]" ], "smiles": [ "COC(=O)c1cccc(NC(=O)Nc2ccc(C(C)(C)C)cc2)c1", "CC(C)(C)c1ccc(NC(=O)Nc2cccc(C(=O)O)c2)cc1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Can you suggest some solvents that might have been used in the given chemical reaction? <molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "A probable solvent could be c1ccncc1 .", "role": "assistant" } ]

{ "selfies": [ "[N][C][C][C][Ring1][Ring1]", "[O][=N+1][Branch1][C][O-1][C][=C][C][=C][C][=C][Ring1][=Branch1][S][=Branch1][C][=O][=Branch1][C][=O][Cl]", "[O][=N+1][Branch1][C][O-1][C][=C][C][=C][C][=C][Ring1][=Branch1][S][=Branch1][C][=O][=Branch1][C][=O][N][C][C][C][Ring1][Ring1]" ], "smiles": [ "NC1CC1", "O=[N+]([O-])c1ccccc1S(=O)(=O)Cl", "O=[N+]([O-])c1ccccc1S(=O)(=O)NC1CC1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given this chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>, what are some solvents that could have been used?", "role": "user" }, { "content": "ClCCl .", "role": "assistant" } ]

{ "selfies": [ "[O][=N+1][Branch1][C][O-1][C][=C][C][Branch1][C][Cl][=C][Branch2][Ring1][#C][O][C][=C][C][=C][Branch2][Ring1][Ring1][S][=Branch1][C][=O][=Branch1][C][=O][C][=C][C][=C][Branch1][C][Cl][C][=C][Ring1][#Branch1][C][=C][Ring1][S][C][Branch1][C][Cl][=C][Ring2][Ring1][=Branch2]", "[N][C][=C][C][Branch1][C][Cl][=C][Branch2][Ring1][#C][O][C][=C][C][=C][Branch2][Ring1][Ring1][S][=Branch1][C][=O][=Branch1][C][=O][C][=C][C][=C][Branch1][C][Cl][C][=C][Ring1][#Branch1][C][=C][Ring1][S][C][Branch1][C][Cl][=C][Ring2][Ring1][=Branch2]" ], "smiles": [ "O=[N+]([O-])c1cc(Cl)c(Oc2ccc(S(=O)(=O)c3ccc(Cl)cc3)cc2)c(Cl)c1", "Nc1cc(Cl)c(Oc2ccc(S(=O)(=O)c3ccc(Cl)cc3)cc2)c(Cl)c1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given the following reaction <molecule_2d>>><molecule_2d>, what are some possible solvents that could have been utilized?", "role": "user" }, { "content": "C1COCCO1 .", "role": "assistant" } ]

{ "selfies": [ "[O][=C][Branch2][Ring1][=Branch2][N][C][C][C][=C][Branch1][C][F][C][=C][Branch1][C][Cl][C][Branch1][C][O][=C][Ring1][=Branch2][C][C][Ring1][=C][C][Branch1][C][F][Branch1][C][F][F]", "[O][=S][=Branch1][C][=O][Branch1][P][O][S][=Branch1][C][=O][=Branch1][C][=O][C][Branch1][C][F][Branch1][C][F][F][C][Branch1][C][F][Branch1][C][F][F]", "[O][=C][Branch2][Ring2][=Branch2][N][C][C][C][=C][Branch1][C][F][C][=C][Branch1][C][Cl][C][Branch1][P][O][S][=Branch1][C][=O][=Branch1][C][=O][C][Branch1][C][F][Branch1][C][F][F][=C][Ring1][S][C][C][Ring2][Ring1][Branch1][C][Branch1][C][F][Branch1][C][F][F]" ], "smiles": [ "O=C(N1CCc2c(F)cc(Cl)c(O)c2CC1)C(F)(F)F", "O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F", "O=C(N1CCc2c(F)cc(Cl)c(OS(=O)(=O)C(F)(F)F)c2CC1)C(F)(F)F" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Please suggest some possible solvents that could have been used in the following chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>.", "role": "user" }, { "content": "ClCCl .", "role": "assistant" } ]

{ "selfies": [ "[C][O][C][=C][C][Branch1][=Branch1][N+1][=Branch1][C][=O][O-1][=C][C][=C][Ring1][=Branch2][N][C][=N][C][Branch1][=Branch1][C][Branch1][C][F][F][=C][Ring1][Branch2]", "[C][O][C][=C][C][Branch1][C][N][=C][C][=C][Ring1][#Branch1][N][C][=N][C][Branch1][=Branch1][C][Branch1][C][F][F][=C][Ring1][Branch2]" ], "smiles": [ "COc1cc([N+](=O)[O-])ccc1-n1cnc(C(F)F)c1", "COc1cc(N)ccc1-n1cnc(C(F)F)c1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Can you suggest some solvents that might have been used in the given chemical reaction? <molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "A probable solvent could be CO .", "role": "assistant" } ]

{ "selfies": [ "[C][I]", "[O][=C][C][=C][Branch1][C][I][C][=C][NH1][Ring1][#Branch1]", "[C][N][C][=C][C][Branch1][C][I][=C][C][Ring1][#Branch1][=O]" ], "smiles": [ "CI", "O=c1cc(I)cc[nH]1", "Cn1ccc(I)cc1=O" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>.<molecule_2d>>><molecule_2d> From the provided chemical reaction, propose some possible solvents that could have been used.", "role": "user" }, { "content": "CCOC(C)=O.CN(C)C=O .", "role": "assistant" } ]

{ "selfies": [ "[C][C][O][C][=Branch1][C][=O][C][C][=C][S][C][=C][C][Branch1][C][O][=C][C][=C][Ring1][#Branch2][Ring1][#Branch1]", "[O][=S][=Branch1][C][=O][Branch1][P][O][S][=Branch1][C][=O][=Branch1][C][=O][C][Branch1][C][F][Branch1][C][F][F][C][Branch1][C][F][Branch1][C][F][F]", "[C][C][O][C][=Branch1][C][=O][C][C][=C][S][C][=C][C][Branch1][P][O][S][=Branch1][C][=O][=Branch1][C][=O][C][Branch1][C][F][Branch1][C][F][F][=C][C][=C][Ring1][P][Ring1][=C]" ], "smiles": [ "CCOC(=O)Cc1csc2cc(O)ccc12", "O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F", "CCOC(=O)Cc1csc2cc(OS(=O)(=O)C(F)(F)F)ccc12" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Please provide possible solvents based on the following chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>.", "role": "user" }, { "content": "CC#N .", "role": "assistant" } ]

{ "selfies": [ "[C][C][Branch1][C][C][Branch1][C][C][O][C][=Branch1][C][=O][O][C][=Branch1][C][=O][O][C][Branch1][C][C][Branch1][C][C][C]", "[N][C][=C][C][=C][Branch1][C][O][C][=C][Ring1][#Branch1]", "[C][C][Branch1][C][C][Branch1][C][C][O][C][=Branch1][C][=O][N][C][=C][C][=C][Branch1][C][O][C][=C][Ring1][#Branch1]" ], "smiles": [ "CC(C)(C)OC(=O)OC(=O)OC(C)(C)C", "Nc1ccc(O)cc1", "CC(C)(C)OC(=O)Nc1ccc(O)cc1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given the following chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>, what are some potential solvents that could have been employed?", "role": "user" }, { "content": "C1COCCO1.O .", "role": "assistant" } ]

{ "selfies": [ "[C][O][C][=C][C][Branch1][=Branch1][C][Branch1][C][C][=O][=C][C][=C][Ring1][=Branch2][O][C][C][C][Cl]", "[F][C][=C][C][=C][C][Branch1][=Branch2][C][C][C][N][C][C][Ring1][=Branch1][=N][NH1][C][Ring1][O][=C][Ring1][#C]", "[C][O][C][=C][C][Branch1][=Branch1][C][Branch1][C][C][=O][=C][C][=C][Ring1][=Branch2][O][C][C][C][N][C][C][C][Branch1][P][C][=N][NH1][C][=C][C][Branch1][C][F][=C][C][=C][Ring1][#Branch2][Ring1][#Branch1][C][C][Ring1][S]" ], "smiles": [ "COc1cc(C(C)=O)ccc1OCCCCl", "Fc1ccc2c(C3CCNCC3)n[nH]c2c1", "COc1cc(C(C)=O)ccc1OCCCN1CCC(c2n[nH]c3cc(F)ccc23)CC1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given this chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>, what are some solvents that could have been used?", "role": "user" }, { "content": "O .", "role": "assistant" } ]

{ "selfies": [ "[F][C][=C][C][=C][Branch1][Branch2][O][C][C][N][C][Ring1][Ring2][C][=C][Ring1][O]", "[F][C][=C][C][=C][C][Branch1][C][Br][=N][Ring1][#Branch1]", "[F][C][=C][C][=C][Branch2][Ring1][Branch1][O][C][C][N][Branch1][N][C][=C][C][=C][C][Branch1][C][Br][=N][Ring1][#Branch1][C][Ring1][O][C][=C][Ring2][Ring1][C]" ], "smiles": [ "Fc1ccc(OC2CNC2)cc1", "Fc1cccc(Br)n1", "Fc1ccc(OC2CN(c3cccc(Br)n3)C2)cc1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "What solvents could have been utilized in the following chemical reaction? <molecule_2d>.<molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "CC(C)O .", "role": "assistant" } ]

{ "selfies": [ "[C][C][C][C][Branch1][#Branch1][C][=Branch1][C][=O][O][C][C][=C][Branch1][=Branch2][C][=C][C][=C][C][=C][Ring1][=Branch1][N][=C][S][C][=C][Branch2][Ring1][C][C][Ring1][Branch1][=C][Ring1][#C][C][=C][C][=C][Branch1][C][C][C][=C][Ring1][#Branch1][C][C][C][Ring1][=C]", "[C][C][C][C][Branch1][=Branch1][C][=Branch1][C][=O][O][C][=C][Branch1][=Branch2][C][=C][C][=C][C][=C][Ring1][=Branch1][N][=C][S][C][=C][Branch2][Ring1][C][C][Ring1][Branch1][=C][Ring1][#C][C][=C][C][=C][Branch1][C][C][C][=C][Ring1][#Branch1][C][C][C][Ring1][=C]" ], "smiles": [ "CCCC(C(=O)OC)c1c(-c2ccccc2)nc2sc3c(c2c1-c1ccc(C)cc1)CCC3", "CCCC(C(=O)O)c1c(-c2ccccc2)nc2sc3c(c2c1-c1ccc(C)cc1)CCC3" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given this chemical reaction <molecule_2d>>><molecule_2d>, what are some solvents that could have been used?", "role": "user" }, { "content": "CO .", "role": "assistant" } ]

{ "selfies": [ "[C][C][=Branch1][C][=O][C][C][C][O]", "[C][C][Branch1][C][C][Branch1][C][C][Si][Branch1][C][C][Branch1][C][C][Cl]", "[C][C][=Branch1][C][=O][C][C][C][O][Si][Branch1][C][C][Branch1][C][C][C][Branch1][C][C][Branch1][C][C][C]" ], "smiles": [ "CC(=O)CCCO", "CC(C)(C)[Si](C)(C)Cl", "CC(=O)CCCO[Si](C)(C)C(C)(C)C" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Based on the given chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>, suggest some possible solvents.", "role": "user" }, { "content": "The solvent can be CN(C)C=O .", "role": "assistant" } ]

{ "selfies": [ "[O][=C][Branch1][C][O][C][C][=C][C][=C][C][=C][Ring1][=Branch1][O]", "[O][C][C][C][N][C][Ring1][Branch1]", "[O][=C][Branch1][O][C][C][=C][C][=C][C][=C][Ring1][=Branch1][O][N][C][C][C][Branch1][C][O][C][Ring1][=Branch1]" ], "smiles": [ "O=C(O)Cc1ccccc1O", "OC1CCNC1", "O=C(Cc1ccccc1O)N1CCC(O)C1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Based on the given chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>, suggest some possible solvents.", "role": "user" }, { "content": "The solvent can be CN(C)C=O .", "role": "assistant" } ]

{ "selfies": [ "[C][C][O][C][=Branch1][C][=O][C][Branch1][O][C][C][C][=C][C][=C][C][=C][Ring1][=Branch1][O][C][=C][C][=C][Branch1][Branch2][C][=C][C][=C][O][Ring1][Branch1][C][=C][Ring1][O]", "[O][=C][Branch1][C][O][C][Branch1][O][C][C][C][=C][C][=C][C][=C][Ring1][=Branch1][O][C][=C][C][=C][Branch1][Branch2][C][=C][C][=C][O][Ring1][Branch1][C][=C][Ring1][O]" ], "smiles": [ "CCOC(=O)C(CCc1ccccc1)Oc1ccc(-c2ccco2)cc1", "O=C(O)C(CCc1ccccc1)Oc1ccc(-c2ccco2)cc1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Can you provide potential solvents for the following chemical reaction? <molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "CCO .", "role": "assistant" } ]

{ "selfies": [ "[N][C][=C][C][=C][Branch1][C][F][C][=C][Ring1][#Branch1][Br]", "[O][B][Branch1][C][O][C][=C][C][=C][Branch1][C][Cl][C][Branch1][C][F][=C][Ring1][Branch2]", "[N][C][=C][C][=C][Branch1][C][F][C][=C][Ring1][#Branch1][C][=C][C][=C][Branch1][C][Cl][C][Branch1][C][F][=C][Ring1][Branch2]" ], "smiles": [ "Nc1ccc(F)cc1Br", "OB(O)c1ccc(Cl)c(F)c1", "Nc1ccc(F)cc1-c1ccc(Cl)c(F)c1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given this chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>, what are some solvents that could have been used?", "role": "user" }, { "content": "CCO.Cc1ccccc1 .", "role": "assistant" } ]

{ "selfies": [ "[Br][C][C][=C][C][=C][C][=C][Ring1][=Branch1]", "[O][C][=C][C][=C][N][=C][Ring1][=Branch1][C][N][C][=C][N][=C][Ring1][Branch1]", "[C][=C][C][=C][Branch2][Ring1][Ring1][C][O][C][=C][C][=C][N][=C][Ring1][=Branch1][C][N][C][=C][N][=C][Ring1][Branch1][C][=C][Ring2][Ring1][Ring2]" ], "smiles": [ "BrCc1ccccc1", "Oc1cccnc1Cn1ccnc1", "c1ccc(COc2cccnc2Cn2ccnc2)cc1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>.<molecule_2d>>><molecule_2d> From the provided chemical reaction, propose some possible solvents that could have been used.", "role": "user" }, { "content": "CN(C)C=O .", "role": "assistant" } ]

{ "selfies": [ "[C][O][C][C][O][C][C][O][C][=C][C][=C][C][Branch2][Ring1][Ring1][C][=N][C][Branch1][C][C][Branch1][#Branch1][C][=Branch1][C][=O][O][C][C][N][Ring1][#Branch2][=C][Ring1][S][O]", "[C][O][C][C][O][C][C][O][C][=C][C][=C][C][Branch2][Ring1][C][C][=N][C][Branch1][C][C][Branch1][=Branch1][C][=Branch1][C][=O][O][C][N][Ring1][=Branch2][=C][Ring1][#C][O]" ], "smiles": [ "COCCOCCOc1cccc(C2=NC(C)(C(=O)OC)CN2)c1O", "COCCOCCOc1cccc(C2=NC(C)(C(=O)O)CN2)c1O" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>>><molecule_2d> Please propose potential solvents that might have been utilized in the provided chemical reaction.", "role": "user" }, { "content": "Sure. A potential answer could be: CO .", "role": "assistant" } ]

{ "selfies": [ "[C][O][C][=Branch1][C][=O][C][C][=C][C][Branch1][C][Cl][=C][Branch2][Ring1][#C][O][C][=C][C][=C][Branch1][O][N][C][=Branch1][C][=O][C][Branch1][C][C][C][C][Branch1][Branch2][C][=C][C][=Branch1][C][=O][O][=C][Ring1][P][C][Branch1][C][Cl][=C][Ring2][Ring1][#Branch2]", "[C][C][Branch1][C][C][C][=Branch1][C][=O][N][C][=C][C][=C][Branch2][Ring1][=Branch1][O][C][=C][Branch1][C][Cl][C][=C][Branch1][#Branch1][C][C][=Branch1][C][=O][O][C][=C][Ring1][O][Cl][C][=C][Ring2][Ring1][Ring1][C][=C][C][=Branch1][C][=O][O]" ], "smiles": [ "COC(=O)Cc1cc(Cl)c(Oc2ccc(NC(=O)C(C)C)c(C=CC(=O)O)c2)c(Cl)c1", "CC(C)C(=O)Nc1ccc(Oc2c(Cl)cc(CC(=O)O)cc2Cl)cc1C=CC(=O)O" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>>><molecule_2d> Based on the given chemical reaction, can you propose some likely solvents that might have been utilized?", "role": "user" }, { "content": "A possible solvent can be C1CCOC1 .", "role": "assistant" } ]

{ "selfies": [ "[C][C][O][C][=Branch1][C][=O][C][N][Branch1][P][C][C][=C][C][=C][C][Branch1][=Branch1][N+1][=Branch1][C][=O][O-1][=C][Ring1][=Branch2][C][=Branch1][C][=O][C][Branch1][=C][N][C][=Branch1][C][=O][C][=C][C][=C][C][=C][Ring1][=Branch1][C][Branch1][C][C][C]", "[C][C][O][C][=Branch1][C][=O][C][N][Branch1][=N][C][C][=C][C][=C][C][Branch1][C][N][=C][Ring1][#Branch1][C][=Branch1][C][=O][C][Branch1][=C][N][C][=Branch1][C][=O][C][=C][C][=C][C][=C][Ring1][=Branch1][C][Branch1][C][C][C]" ], "smiles": [ "CCOC(=O)CN(Cc1cccc([N+](=O)[O-])c1)C(=O)C(NC(=O)c1ccccc1)C(C)C", "CCOC(=O)CN(Cc1cccc(N)c1)C(=O)C(NC(=O)c1ccccc1)C(C)C" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given the following chemical reaction <molecule_2d>>><molecule_2d>, what are some potential solvents that could have been employed?", "role": "user" }, { "content": "CO .", "role": "assistant" } ]

{ "selfies": [ "[C][C][=C][Branch1][C][O][C][=C][C][Branch1][=Branch1][N+1][=Branch1][C][=O][O-1][=C][Ring1][#Branch2][C]", "[C][C][=C][Branch1][C][N][C][=C][C][Branch1][C][O][=C][Ring1][Branch2][C]" ], "smiles": [ "Cc1c(O)ccc([N+](=O)[O-])c1C", "Cc1c(N)ccc(O)c1C" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given the following chemical reaction <molecule_2d>>><molecule_2d>, what are some potential solvents that could have been employed?", "role": "user" }, { "content": "CCO .", "role": "assistant" } ]

{ "selfies": [ "[C][C][Branch1][C][C][Branch1][C][C][C][=C][C][Branch1][N][C][=Branch1][C][=O][C][C][=C][NH1][C][=Ring1][Branch1][=C][C][Branch1][=Branch2][C][Branch1][C][C][Branch1][C][C][C][=C][Ring1][P][O]", "[C][I]", "[C][N][C][=C][C][Branch2][Ring2][Ring2][C][=Branch1][C][=O][C][=C][C][Branch1][=Branch2][C][Branch1][C][C][Branch1][C][C][C][=C][Branch1][C][O][C][Branch1][=Branch2][C][Branch1][C][C][Branch1][C][C][C][=C][Ring1][#C][=C][Ring2][Ring1][=Branch1]" ], "smiles": [ "CC(C)(C)c1cc(C(=O)c2cc[nH]c2)cc(C(C)(C)C)c1O", "CI", "Cn1ccc(C(=O)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Please suggest some possible solvents that could have been used in the following chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>.", "role": "user" }, { "content": "CN(C)C=O .", "role": "assistant" } ]

{ "selfies": [ "[C][I]", "[O][=N+1][Branch1][C][O-1][C][=C][C][Branch1][C][Cl][=C][C][Branch1][C][Cl][=C][Ring1][Branch2][O]", "[C][O][C][=C][Branch1][C][Cl][C][=C][Branch1][C][Cl][C][=C][Ring1][Branch2][N+1][=Branch1][C][=O][O-1]" ], "smiles": [ "CI", "O=[N+]([O-])c1cc(Cl)cc(Cl)c1O", "COc1c(Cl)cc(Cl)cc1[N+](=O)[O-]" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>.<molecule_2d>>><molecule_2d> Please propose potential solvents that might have been utilized in the provided chemical reaction.", "role": "user" }, { "content": "Sure. A potential answer could be: CN(C)C=O .", "role": "assistant" } ]

{ "selfies": [ "[C][C][Branch1][C][C][Branch1][C][C][O][C][=Branch1][C][=O][N][C][C][Branch1][C][O][C][C][Ring1][=Branch1][C][=Branch1][C][=O][O]", "[C][O][C][=C][N][=C][Branch1][C][Cl][C][=C][C][=C][C][=C][Ring1][O][Ring1][=Branch1]", "[C][O][C][=C][N][=C][Branch2][Ring1][#C][O][C][C][C][Branch1][=Branch1][C][=Branch1][C][=O][O][N][Branch1][=C][C][=Branch1][C][=O][O][C][Branch1][C][C][Branch1][C][C][C][C][Ring1][#C][C][=C][C][=C][C][=C][Ring2][Ring1][#Branch2][Ring1][=Branch1]" ], "smiles": [ "CC(C)(C)OC(=O)N1CC(O)CC1C(=O)O", "COc1cnc(Cl)c2ccccc12", "COc1cnc(OC2CC(C(=O)O)N(C(=O)OC(C)(C)C)C2)c2ccccc12" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "What solvents could have been utilized in the following chemical reaction? <molecule_2d>.<molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "CS(C)=O .", "role": "assistant" } ]

{ "selfies": [ "[C][C][O][C][C][N][Ring1][=Branch1]", "[C][C][C][Branch1][Ring1][C][#N][Branch1][=Branch1][C][=Branch1][C][=O][Cl][C][=C][C][=C][C][=C][Ring1][=Branch1]", "[C][C][C][Branch1][Ring1][C][#N][Branch1][=N][C][=Branch1][C][=O][N][C][C][O][C][C][Ring1][=Branch1][C][=C][C][=C][C][=C][Ring1][=Branch1]" ], "smiles": [ "C1COCCN1", "CCC(C#N)(C(=O)Cl)c1ccccc1", "CCC(C#N)(C(=O)N1CCOCC1)c1ccccc1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given the following chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>, what are some potential solvents that could have been employed?", "role": "user" }, { "content": "ClCCl .", "role": "assistant" } ]

{ "selfies": [ "[C][C][C][Branch1][C][C][C][Branch2][Ring1][=N][C][N][C][=C][C][=C][Branch1][P][O][Si][Branch1][C][C][Branch1][C][C][C][Branch1][C][C][Branch1][C][C][C][C][=C][Ring1][=C][N][C][=Branch1][C][=O][O][C][Branch1][C][C][Branch1][C][C][C]", "[O][=C][Branch1][C][O][C][C][C][Ring1][Ring1][C][=C][C][=C][C][=N][Ring1][=Branch1]", "[C][C][C][Branch1][C][C][C][Branch2][Ring2][P][C][N][Branch2][Ring1][C][C][=Branch1][C][=O][C][C][C][Ring1][Ring1][C][=C][C][=C][C][=N][Ring1][=Branch1][C][=C][C][=C][Branch1][P][O][Si][Branch1][C][C][Branch1][C][C][C][Branch1][C][C][Branch1][C][C][C][C][=C][Ring1][=C][N][C][=Branch1][C][=O][O][C][Branch1][C][C][Branch1][C][C][C]" ], "smiles": [ "CCC(C)C(CNc1ccc(O[Si](C)(C)C(C)(C)C)cc1)NC(=O)OC(C)(C)C", "O=C(O)C1CC1c1ccccn1", "CCC(C)C(CN(C(=O)C1CC1c1ccccn1)c1ccc(O[Si](C)(C)C(C)(C)C)cc1)NC(=O)OC(C)(C)C" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>.<molecule_2d>>><molecule_2d> Please propose potential solvents that might have been utilized in the provided chemical reaction.", "role": "user" }, { "content": "Sure. A potential answer could be: CCOCC.ClCCl .", "role": "assistant" } ]

{ "selfies": [ "[N][C][=C][C][=C][C][=C][Ring1][=Branch1][S][Branch1][C][N][=Branch1][C][=O][=O]", "[O][=C][Branch1][C][O][C][=C][C][=C][Branch1][O][C][#C][C][=C][C][=C][C][=C][Ring1][=Branch1][C][=C][Ring1][=C]", "[N][S][=Branch1][C][=O][=Branch1][C][=O][C][=C][C][=C][C][=C][Ring1][=Branch1][N][C][=Branch1][C][=O][C][=C][C][=C][Branch1][O][C][#C][C][=C][C][=C][C][=C][Ring1][=Branch1][C][=C][Ring1][=C]" ], "smiles": [ "Nc1ccccc1S(N)(=O)=O", "O=C(O)c1ccc(C#Cc2ccccc2)cc1", "NS(=O)(=O)c1ccccc1NC(=O)c1ccc(C#Cc2ccccc2)cc1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given this chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>, what are some solvents that could have been used?", "role": "user" }, { "content": "c1ccccc1 .", "role": "assistant" } ]

{ "selfies": [ "[O][=C][N][Branch2][Ring1][=Branch1][C][C][=C][C][=C][Branch1][=Branch2][C][Branch1][C][F][Branch1][C][F][F][N][=C][Ring1][#Branch2][C][O][N][=C][C][Branch1][=Branch2][C][=C][C][=N][C][=C][Ring1][=Branch1][=C][Branch1][N][C][=C][C][=C][Branch1][C][Cl][C][=C][Ring1][#Branch1][C][=C][N][Ring2][Ring2][Ring1][Ring2][Ring1][Ring1]", "[O][=C][C][=N][C][Branch1][=Branch2][C][Branch1][C][F][Branch1][C][F][F][=C][C][=C][Ring1][#Branch2][C][N][N][=C][C][Branch1][=Branch2][C][=C][C][=N][C][=C][Ring1][=Branch1][=C][Branch1][N][C][=C][C][=C][Branch1][C][Cl][C][=C][Ring1][#Branch1][C][=C][N][Ring2][Ring1][Ring1][C][Ring2][Ring1][=Branch1][=O]" ], "smiles": [ "O=c1n(Cc2ccc(C(F)(F)F)nc2CO)nc2c(-c3ccncc3)c(-c3ccc(Cl)cc3)ccn12", "O=Cc1nc(C(F)(F)F)ccc1Cn1nc2c(-c3ccncc3)c(-c3ccc(Cl)cc3)ccn2c1=O" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Please provide possible solvents based on the following chemical reaction <molecule_2d>>><molecule_2d>.", "role": "user" }, { "content": "ClCCl .", "role": "assistant" } ]

{ "selfies": [ "[C][C][Branch1][C][C][Branch1][C][C][O][C][=Branch1][C][=O][N][C][C][Branch1][C][O][C][Ring1][Branch1]", "[O][=N+1][Branch1][C][O-1][C][=C][C][=C][N][=C][Ring1][=Branch1][F]", "[C][C][Branch1][C][C][Branch1][C][C][O][C][=Branch1][C][=O][N][C][C][Branch1][#C][O][C][=N][C][=C][C][=C][Ring1][=Branch1][N+1][=Branch1][C][=O][O-1][C][Ring1][=C]" ], "smiles": [ "CC(C)(C)OC(=O)N1CC(O)C1", "O=[N+]([O-])c1cccnc1F", "CC(C)(C)OC(=O)N1CC(Oc2ncccc2[N+](=O)[O-])C1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>.<molecule_2d>>><molecule_2d> Based on the given chemical reaction, can you propose some likely solvents that might have been utilized?", "role": "user" }, { "content": "A possible solvent can be C1CCOC1 .", "role": "assistant" } ]

{ "selfies": [ "[O][=C][Branch1][C][Cl][C][=C][C][=C][C][=C][Ring1][=Branch1]", "[O][=C][Branch1][#Branch2][N][C][C][C][N][C][C][Ring1][=Branch1][C][=C][C][=C][C][=C][Ring1][=Branch1][O][C][=C][C][=C][Branch1][C][Cl][C][=C][Ring1][#Branch1][Cl]", "[O][=C][Branch2][Ring1][Branch2][N][C][C][C][N][Branch1][=N][C][=Branch1][C][=O][C][=C][C][=C][C][=C][Ring1][=Branch1][C][C][Ring1][=C][C][=C][C][=C][C][=C][Ring1][=Branch1][O][C][=C][C][=C][Branch1][C][Cl][C][=C][Ring1][#Branch1][Cl]" ], "smiles": [ "O=C(Cl)c1ccccc1", "O=C(NC1CCNCC1)c1ccccc1Oc1ccc(Cl)cc1Cl", "O=C(NC1CCN(C(=O)c2ccccc2)CC1)c1ccccc1Oc1ccc(Cl)cc1Cl" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Can you suggest some solvents that might have been used in the given chemical reaction? <molecule_2d>.<molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "A probable solvent could be ClCCl .", "role": "assistant" } ]

{ "selfies": [ "[C][C][Branch1][C][C][Si][Branch1][=C][O][C][=C][C][=C][Branch1][Ring1][C][Br][C][=C][Ring1][Branch2][Branch1][=Branch1][C][Branch1][C][C][C][C][Branch1][C][C][C]", "[C][C][=C][C][Branch2][Ring1][=C][C][=N][C][Branch2][Ring1][Ring2][C][=C][C][=C][Branch1][#Branch2][O][C][Branch1][C][F][Branch1][C][F][F][C][=C][Ring1][O][=N][O][Ring1][S][=N][NH1][Ring2][Ring1][Branch1]", "[C][C][=C][C][Branch2][Ring1][=C][C][=N][C][Branch2][Ring1][Ring2][C][=C][C][=C][Branch1][#Branch2][O][C][Branch1][C][F][Branch1][C][F][F][C][=C][Ring1][O][=N][O][Ring1][S][=N][N][Ring2][Ring1][Branch1][C][C][=C][C][=C][Branch2][Ring1][=Branch1][O][Si][Branch1][=Branch1][C][Branch1][C][C][C][Branch1][=Branch1][C][Branch1][C][C][C][C][Branch1][C][C][C][C][=C][Ring1][P]" ], "smiles": [ "CC(C)[Si](Oc1ccc(CBr)cc1)(C(C)C)C(C)C", "Cc1cc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)n[nH]1", "Cc1cc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)nn1Cc1ccc(O[Si](C(C)C)(C(C)C)C(C)C)cc1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Can you suggest some solvents that might have been used in the given chemical reaction? <molecule_2d>.<molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "A probable solvent could be C1CCOC1 .", "role": "assistant" } ]

{ "selfies": [ "[C][O]", "[O][=C][Branch1][C][Cl][C][=C][C][=C][Branch1][=Branch2][S][=Branch1][C][=O][=Branch1][C][=O][Cl][C][=C][Ring1][#Branch2]", "[C][O][C][=Branch1][C][=O][C][=C][C][=C][Branch1][=Branch2][S][=Branch1][C][=O][=Branch1][C][=O][Cl][C][=C][Ring1][#Branch2]" ], "smiles": [ "CO", "O=C(Cl)c1ccc(S(=O)(=O)Cl)cc1", "COC(=O)c1ccc(S(=O)(=O)Cl)cc1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given the following chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>, what are some potential solvents that could have been employed?", "role": "user" }, { "content": "O .", "role": "assistant" } ]

{ "selfies": [ "[C][O][C][=Branch1][C][=O][C][=C][C][=Branch1][C][=O][C][O][C][=C][C][=C][Branch1][C][Cl][C][=C][Ring1][#Branch1][C][=Branch1][C][=O][C][=Ring1][N][NH1][Ring1][P]", "[O][=C][Branch1][C][O][C][=C][C][=Branch1][C][=O][C][O][C][=C][C][=C][Branch1][C][Cl][C][=C][Ring1][#Branch1][C][=Branch1][C][=O][C][=Ring1][N][NH1][Ring1][P]" ], "smiles": [ "COC(=O)c1cc(=O)c2oc3ccc(Cl)cc3c(=O)c2[nH]1", "O=C(O)c1cc(=O)c2oc3ccc(Cl)cc3c(=O)c2[nH]1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "What solvents could have been utilized in the following chemical reaction? <molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "[Na+].[OH-] .", "role": "assistant" } ]

{ "selfies": [ "[C][N][C][C][N][C][C][Ring1][=Branch1]", "[O][=C][Branch1][C][O][C][=C][N][Branch1][=Branch1][C][C][C][Ring1][Ring1][C][=C][C][Branch1][C][Cl][=C][Branch1][C][F][C][=C][Ring1][Branch2][C][Ring1][#C][=O]", "[C][N][C][C][N][Branch2][Ring1][P][C][=C][C][=C][Branch1][=Branch1][C][=C][Ring1][=Branch1][F][C][=Branch1][C][=O][C][Branch1][=Branch1][C][=Branch1][C][=O][O][=C][N][Ring1][=N][C][C][C][Ring1][Ring1][C][C][Ring2][Ring1][Branch2]" ], "smiles": [ "CN1CCNCC1", "O=C(O)c1cn(C2CC2)c2cc(Cl)c(F)cc2c1=O", "CN1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Please provide possible solvents based on the following chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>.", "role": "user" }, { "content": "CS(C)=O .", "role": "assistant" } ]

{ "selfies": [ "[C][O][C][=C][C][=C][Branch2][Branch1][Ring2][C][N][C][C][C][=C][Branch2][Ring1][=Branch1][S][C][Branch1][C][N][=C][Ring1][=Branch1][C][=Branch1][C][=O][O][C][Branch1][C][C][Branch1][C][C][C][C][Ring1][P][C][N][C][=Branch1][C][=O][C][=C][C][=C][C][=C][Ring1][=Branch1][C][Ring1][#Branch2][=O][C][=C][Ring2][Ring2][Ring2]", "[C][O][C][=C][C][=C][Branch2][Ring2][Ring2][C][N][C][C][C][=C][Branch2][Ring1][=Branch1][S][C][Branch1][C][N][=C][Ring1][=Branch1][C][=Branch1][C][=O][O][C][Branch1][C][C][Branch1][C][C][C][C][Ring1][P][C][N][C][=C][Ring2][Ring1][#Branch2]" ], "smiles": [ "COc1ccc(CN2CCc3c(sc(N)c3C(=O)OC(C)(C)C)C2CN2C(=O)c3ccccc3C2=O)cc1", "COc1ccc(CN2CCc3c(sc(N)c3C(=O)OC(C)(C)C)C2CN)cc1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>>><molecule_2d> Please propose potential solvents that might have been utilized in the provided chemical reaction.", "role": "user" }, { "content": "Sure. A potential answer could be: CCO .", "role": "assistant" } ]

{ "selfies": [ "[C][O][C][C][O]", "[C][O][C][=C][C][Branch1][C][F][=C][Branch1][Ring1][C][#N][C][Branch1][C][F][=C][Ring1][#Branch2]", "[C][O][C][C][O][C][=C][C][Branch1][Ring1][O][C][=C][C][Branch1][C][F][=C][Ring1][=Branch2][C][#N]" ], "smiles": [ "COCCO", "COc1cc(F)c(C#N)c(F)c1", "COCCOc1cc(OC)cc(F)c1C#N" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Please suggest some possible solvents that could have been used in the following chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>.", "role": "user" }, { "content": "C1CCOC1 .", "role": "assistant" } ]

{ "selfies": [ "[C][C][Branch1][C][C][Branch1][Ring1][C][O][C][Br]", "[C][C][O][C][=C][C][=C][Branch1][#C][C][=C][C][=C][C][=C][Ring1][=Branch1][C][C][C][Ring1][Branch1][=O][C][Branch1][C][O][=C][Ring1][P][O][C]", "[C][C][O][C][=C][C][=C][Branch1][#C][C][=C][C][=C][C][=C][Ring1][=Branch1][C][C][C][Ring1][Branch1][=O][C][Branch1][N][O][C][C][Branch1][C][C][Branch1][C][C][C][O][=C][Ring2][Ring1][#Branch1][O][C]" ], "smiles": [ "CC(C)(CO)CBr", "CCOc1ccc(-c2cccc3c2CCC3=O)c(O)c1OC", "CCOc1ccc(-c2cccc3c2CCC3=O)c(OCC(C)(C)CO)c1OC" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Can you provide potential solvents for the following chemical reaction? <molecule_2d>.<molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "CC#N .", "role": "assistant" } ]

{ "selfies": [ "[C][C][Branch1][C][C][Branch1][C][C][O][C][=Branch1][C][=O][N][C][C][C][C][Branch2][Ring2][=N][C][C][C][N][C][Branch1][=C][C][O][C][=C][C][=C][Branch1][C][Cl][C][=C][Ring1][#Branch1][=N][C][=C][Branch1][O][O][C][C][=C][C][=C][C][=C][Ring1][=Branch1][C][=C][C][=C][Ring1][=C][Ring2][Ring1][#Branch2][C][Ring2][Ring2][Ring1]", "[C][C][Branch1][C][C][Branch1][C][C][O][C][=Branch1][C][=O][N][C][C][C][C][Branch2][Ring2][Ring2][C][C][C][N][C][Branch1][=C][C][O][C][=C][C][=C][Branch1][C][Cl][C][=C][Ring1][#Branch1][=N][C][=C][Branch1][C][O][C][=C][C][=C][Ring1][#Branch1][Ring2][Ring1][Ring1][C][Ring2][Ring1][N]" ], "smiles": [ "CC(C)(C)OC(=O)N1CCCC(CCCn2c(COc3ccc(Cl)cc3)nc3c(OCc4ccccc4)cccc32)C1", "CC(C)(C)OC(=O)N1CCCC(CCCn2c(COc3ccc(Cl)cc3)nc3c(O)cccc32)C1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Based on the given chemical reaction <molecule_2d>>><molecule_2d>, suggest some possible solvents.", "role": "user" }, { "content": "The solvent can be CCOC(C)=O .", "role": "assistant" } ]

{ "selfies": [ "[C][C][=C][C][=C][Branch1][O][C][#C][Si][Branch1][C][C][Branch1][C][C][C][C][=N][Ring1][N]", "[C][#C][C][=C][C][=C][Branch1][C][C][N][=C][Ring1][#Branch1]" ], "smiles": [ "Cc1ccc(C#C[Si](C)(C)C)cn1", "C#Cc1ccc(C)nc1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given the following reaction <molecule_2d>>><molecule_2d>, what are some possible solvents that could have been utilized?", "role": "user" }, { "content": "C1CCOC1 .", "role": "assistant" } ]

{ "selfies": [ "[Cl][C][=C][C][=C][C][Branch1][Ring1][C][Br][=C][Ring1][Branch2]", "[N][C][=N][C][=C][C][=C][Ring1][=Branch1][O]", "[N][C][=N][C][=C][C][=C][Ring1][=Branch1][O][C][C][=C][C][=C][C][Branch1][C][Cl][=C][Ring1][#Branch1]" ], "smiles": [ "Clc1cccc(CBr)c1", "Nc1ncccc1O", "Nc1ncccc1OCc1cccc(Cl)c1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>.<molecule_2d>>><molecule_2d> Please propose potential solvents that might have been utilized in the provided chemical reaction.", "role": "user" }, { "content": "Sure. A potential answer could be: CCOC(C)=O.O .", "role": "assistant" } ]

{ "selfies": [ "[C][=C][C][O][C][=C][C][Branch1][C][O][=C][C][=Branch1][Ring2][=C][Ring1][#Branch1][O][C][Branch1][C][C][Branch1][C][C][C][C][Ring1][=Branch2][=O]", "[C][I]", "[C][=C][C][O][C][=C][C][Branch1][Ring1][O][C][=C][C][=Branch1][Ring2][=C][Ring1][Branch2][O][C][Branch1][C][C][Branch1][C][C][C][C][Ring1][=Branch2][=O]" ], "smiles": [ "C=CCOc1cc(O)c2c(c1)OC(C)(C)CC2=O", "CI", "C=CCOc1cc(OC)c2c(c1)OC(C)(C)CC2=O" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>.<molecule_2d>>><molecule_2d> Please propose potential solvents that might have been utilized in the provided chemical reaction.", "role": "user" }, { "content": "Sure. A potential answer could be: CCOC(C)=O.CN(C)C=O .", "role": "assistant" } ]

{ "selfies": [ "[C][C][O][C][=Branch1][C][=O][C][C][C][Br]", "[O][=C][C][=C][C][=C][Branch1][C][O][C][=C][Ring1][#Branch1]", "[C][C][O][C][=Branch1][C][=O][C][C][C][O][C][=C][C][=C][Branch1][Ring1][C][=O][C][=C][Ring1][Branch2]" ], "smiles": [ "CCOC(=O)CCCBr", "O=Cc1ccc(O)cc1", "CCOC(=O)CCCOc1ccc(C=O)cc1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given the following chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>, what are some potential solvents that could have been employed?", "role": "user" }, { "content": "CC#N .", "role": "assistant" } ]

{ "selfies": [ "[Br][C][=C][C][=C][C][=C][Ring1][=Branch1]", "[C][#C][N][C][=C][Branch1][=C][C][=C][C][Branch1][C][C][=C][C][=C][Ring1][#Branch1][Ring1][#Branch2][C][N][Branch1][C][C][C][C][Ring1][=C]", "[C][C][=C][C][=C][C][=Branch1][Ring2][=C][Ring1][=Branch1][C][=C][Branch1][=C][N][Ring1][=Branch1][C][#C][C][=C][C][=C][C][=C][Ring1][=Branch1][C][C][N][Branch1][C][C][C][Ring1][S]" ], "smiles": [ "Brc1ccccc1", "C#Cn1c2c(c3cc(C)ccc31)CN(C)CC2", "Cc1ccc2c(c1)c1c(n2C#Cc2ccccc2)CCN(C)C1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Please suggest some possible solvents that could have been used in the following chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>.", "role": "user" }, { "content": "O .", "role": "assistant" } ]

{ "selfies": [ "[C][S][=Branch1][C][=O][=Branch1][C][=O][Cl]", "[C][N][C][Branch1][Ring1][C][O][=C][Branch1][N][C][=C][C][=C][Branch1][C][Cl][C][=C][Ring1][#Branch1][C][C][=C][N][Branch1][#Branch2][C][C][=C][C][=C][C][=C][Ring1][=Branch1][C][=Ring1][N][C][Ring2][Ring1][=Branch2][=O]", "[C][N][C][Branch1][O][C][O][S][Branch1][C][C][=Branch1][C][=O][=O][=C][Branch1][N][C][=C][C][=C][Branch1][C][Cl][C][=C][Ring1][#Branch1][C][C][=C][N][Branch1][#Branch2][C][C][=C][C][=C][C][=C][Ring1][=Branch1][C][=Ring1][N][C][Ring2][Ring1][=N][=O]" ], "smiles": [ "CS(=O)(=O)Cl", "Cn1c(CO)c(-c2ccc(Cl)cc2)c2ccn(Cc3ccccc3)c2c1=O", "Cn1c(COS(C)(=O)=O)c(-c2ccc(Cl)cc2)c2ccn(Cc3ccccc3)c2c1=O" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Please suggest some possible solvents that could have been used in the following chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>.", "role": "user" }, { "content": "ClCCl .", "role": "assistant" } ]

{ "selfies": [ "[C][C][C][C][C][C][C][C][Branch1][=Branch1][C][=Branch1][C][=O][O][C][Ring1][#Branch1]", "[O][=S][Branch1][C][Cl][Cl]", "[C][C][C][C][C][C][C][C][Branch1][=Branch1][C][=Branch1][C][=O][Cl][C][Ring1][#Branch1]" ], "smiles": [ "CCCCCC1CC(C(=O)O)C1", "O=S(Cl)Cl", "CCCCCC1CC(C(=O)Cl)C1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given the following reaction <molecule_2d>.<molecule_2d>>><molecule_2d>, what are some possible solvents that could have been utilized?", "role": "user" }, { "content": "c1ccccc1 .", "role": "assistant" } ]

{ "selfies": [ "[N][C][=C][C][=C][C][=C][Ring1][=Branch1][F]", "[O][=C][Branch1][C][Cl][C][C][Cl]", "[O][=C][Branch1][Ring2][C][C][Cl][N][C][=C][C][=C][C][=C][Ring1][=Branch1][F]" ], "smiles": [ "Nc1ccccc1F", "O=C(Cl)CCCl", "O=C(CCCl)Nc1ccccc1F" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Please provide possible solvents based on the following chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>.", "role": "user" }, { "content": "ClCCl.O .", "role": "assistant" } ]

{ "selfies": [ "[C][C][O][C][=Branch1][C][=O][C][=C][C][=C][C][=C][Branch1][=Branch1][C][Branch1][C][N][=O][NH1][C][Ring1][Branch2][=C][Ring1][N]", "[N][C][=Branch1][C][=O][C][=C][C][=C][C][=C][Branch1][=Branch1][C][=Branch1][C][=O][O][C][=C][Ring1][=Branch2][NH1][Ring1][N]" ], "smiles": [ "CCOC(=O)c1ccc2cc(C(N)=O)[nH]c2c1", "NC(=O)c1cc2ccc(C(=O)O)cc2[nH]1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>>><molecule_2d> From the provided chemical reaction, propose some possible solvents that could have been used.", "role": "user" }, { "content": "CO .", "role": "assistant" } ]

{ "selfies": [ "[C][C][Branch1][C][C][Branch1][C][N][C][O]", "[O][=N+1][Branch1][C][O-1][C][=C][C][Branch1][=Branch2][C][Branch1][C][F][Branch1][C][F][F][=C][N][=C][Ring1][#Branch2][Cl]", "[C][C][Branch1][C][C][Branch1][Ring1][C][O][N][C][=N][C][=C][Branch1][=Branch2][C][Branch1][C][F][Branch1][C][F][F][C][=C][Ring1][#Branch2][N+1][=Branch1][C][=O][O-1]" ], "smiles": [ "CC(C)(N)CO", "O=[N+]([O-])c1cc(C(F)(F)F)cnc1Cl", "CC(C)(CO)Nc1ncc(C(F)(F)F)cc1[N+](=O)[O-]" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>.<molecule_2d>>><molecule_2d> Based on the given chemical reaction, can you propose some likely solvents that might have been utilized?", "role": "user" }, { "content": "A possible solvent can be CCOC(C)=O.CN(C)C=O .", "role": "assistant" } ]

{ "selfies": [ "[N][S][=Branch1][C][=O][=Branch1][C][=O][C][=C][C][Branch1][=Branch1][C][=Branch1][C][=O][O][=C][Branch1][C][Cl][C][=C][Ring1][#Branch2][F]", "[N][S][=Branch1][C][=O][=Branch1][C][=O][C][=C][C][Branch1][Ring1][C][O][=C][Branch1][C][Cl][C][=C][Ring1][=Branch2][F]" ], "smiles": [ "NS(=O)(=O)c1cc(C(=O)O)c(Cl)cc1F", "NS(=O)(=O)c1cc(CO)c(Cl)cc1F" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>>><molecule_2d> From the provided chemical reaction, propose some possible solvents that could have been used.", "role": "user" }, { "content": "C1CCOC1 .", "role": "assistant" } ]

{ "selfies": [ "[C][C][O][C][=Branch1][C][=O][C][C][N][Branch1][C][C][C][=Branch1][C][=O][C][=C][C][=C][Branch2][Ring1][P][N][C][Branch1][#Branch1][C][C][Branch1][C][C][C][C][C][=C][Branch1][=N][C][=C][C][=C][Branch1][Ring1][O][C][N][=C][Ring1][Branch2][O][C][=Ring1][=N][C][C][=C][Ring2][Ring1][#Branch2]", "[C][O][C][=C][C][=C][Branch2][Branch1][C][C][=C][C][Branch2][Ring2][Ring2][C][Branch1][#Branch1][C][C][Branch1][C][C][C][N][C][=C][C][=C][Branch1][S][C][=Branch1][C][=O][N][Branch1][C][C][C][C][C][=Branch1][C][=O][O][C][=C][Ring1][#C][=C][Branch1][C][C][O][Ring2][Ring1][O][C][=N][Ring2][Ring1][P]" ], "smiles": [ "CCOC(=O)CCN(C)C(=O)c1ccc(NC(CC(C)C)c2cc(-c3ccc(OC)nc3)oc2C)cc1", "COc1ccc(-c2cc(C(CC(C)C)Nc3ccc(C(=O)N(C)CCC(=O)O)cc3)c(C)o2)cn1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>>><molecule_2d> From the provided chemical reaction, propose some possible solvents that could have been used.", "role": "user" }, { "content": "CCO .", "role": "assistant" } ]

{ "selfies": [ "[C][C][Branch1][C][C][Branch1][C][C][O][C][=Branch1][C][=O][C][Branch1][Branch2][C][C][C][Branch1][C][N][=O][N][C][=Branch1][C][=O][C][=C][C][=C][Branch2][Ring1][Branch2][N][C][Branch1][=Branch2][C][N][C][=C][N][=C][Ring1][Branch1][C][=C][C][=C][Branch1][C][F][C][=C][Ring1][#Branch1][C][=C][Ring2][Ring1][Branch1][C][=C][C][=C][C][=C][Ring1][=Branch1]", "[N][C][=Branch1][C][=O][C][C][C][Branch2][Ring2][P][N][C][=Branch1][C][=O][C][=C][C][=C][Branch2][Ring1][Branch2][N][C][Branch1][=Branch2][C][N][C][=C][N][=C][Ring1][Branch1][C][=C][C][=C][Branch1][C][F][C][=C][Ring1][#Branch1][C][=C][Ring2][Ring1][Branch1][C][=C][C][=C][C][=C][Ring1][=Branch1][C][=Branch1][C][=O][O]" ], "smiles": [ "CC(C)(C)OC(=O)C(CCC(N)=O)NC(=O)c1ccc(NC(Cn2ccnc2)c2ccc(F)cc2)cc1-c1ccccc1", "NC(=O)CCC(NC(=O)c1ccc(NC(Cn2ccnc2)c2ccc(F)cc2)cc1-c1ccccc1)C(=O)O" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Please suggest some possible solvents that could have been used in the following chemical reaction <molecule_2d>>><molecule_2d>.", "role": "user" }, { "content": "O=C(O)C(F)(F)F .", "role": "assistant" } ]

{ "selfies": [ "[C][C][Branch1][C][C][O][B][Branch2][Ring1][Ring2][B][O][C][Branch1][C][C][Branch1][C][C][C][Branch1][C][C][Branch1][C][C][O][Ring1][=Branch2][O][C][Ring1][#C][Branch1][C][C][C]", "[C][C][S][C][=C][C][Branch1][C][Br][=C][C][Branch1][=Branch2][C][Branch1][C][F][Branch1][C][F][F][=C][Ring1][O]", "[C][C][S][C][=C][C][Branch2][Ring1][Ring2][B][O][C][Branch1][C][C][Branch1][C][C][C][Branch1][C][C][Branch1][C][C][O][Ring1][=Branch2][=C][C][Branch1][=Branch2][C][Branch1][C][F][Branch1][C][F][F][=C][Ring2][Ring1][Ring1]" ], "smiles": [ "CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C", "CCSc1cc(Br)cc(C(F)(F)F)c1", "CCSc1cc(B2OC(C)(C)C(C)(C)O2)cc(C(F)(F)F)c1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Can you provide potential solvents for the following chemical reaction? <molecule_2d>.<molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "CS(C)=O .", "role": "assistant" } ]

{ "selfies": [ "[O][=C][Branch1][O][O][C][C][=C][C][=C][C][=C][Ring1][=Branch1][C][C][C][C][=C][C][Branch1][O][O][C][C][=C][C][=C][C][=C][Ring1][=Branch1][=C][C][=C][Ring1][=C][C][Ring2][Ring1][C]", "[O][=C][Branch1][C][O][C][C][C][C][=C][C][Branch1][O][O][C][C][=C][C][=C][C][=C][Ring1][=Branch1][=C][C][=C][Ring1][=C][C][Ring2][Ring1][C]" ], "smiles": [ "O=C(OCc1ccccc1)C1CCc2cc(OCc3ccccc3)ccc2C1", "O=C(O)C1CCc2cc(OCc3ccccc3)ccc2C1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Can you provide potential solvents for the following chemical reaction? <molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "CCO.O .", "role": "assistant" } ]

{ "selfies": [ "[C][S][=Branch1][C][=O][=Branch1][C][=O][N][C][C][C][C][C][C][=Branch1][C][=O][O]", "[N][C][=C][C][=C][C][=C][Ring1][=Branch1]", "[C][S][=Branch1][C][=O][=Branch1][C][=O][N][C][C][C][C][C][C][=Branch1][C][=O][N][C][=C][C][=C][C][=C][Ring1][=Branch1]" ], "smiles": [ "CS(=O)(=O)NCCCCCC(=O)O", "Nc1ccccc1", "CS(=O)(=O)NCCCCCC(=O)Nc1ccccc1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Please provide possible solvents based on the following chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>.", "role": "user" }, { "content": "C1CCOC1 .", "role": "assistant" } ]

{ "selfies": [ "[C][C][=C][C][=C][Branch1][=Branch2][S][=Branch1][C][=O][=Branch1][C][=O][Cl][C][=C][Ring1][#Branch2]", "[O][C][C][C][C][Ring1][Ring2]", "[C][C][=C][C][=C][Branch1][#C][S][=Branch1][C][=O][=Branch1][C][=O][O][C][C][C][C][Ring1][Ring2][C][=C][Ring1][=C]" ], "smiles": [ "Cc1ccc(S(=O)(=O)Cl)cc1", "OC1CCC1", "Cc1ccc(S(=O)(=O)OC2CCC2)cc1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given this chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>, what are some solvents that could have been used?", "role": "user" }, { "content": "c1ccncc1 .", "role": "assistant" } ]

{ "selfies": [ "[C][O][C][=Branch1][C][=O][C][N][C][N][Branch1][=Branch2][C][=C][C][=C][C][=C][Ring1][=Branch1][C][Branch2][Ring1][#Branch1][C][C][N][Branch1][=C][C][=Branch1][C][=O][O][C][Branch1][C][C][Branch1][C][C][C][C][C][Ring1][=N][C][Ring2][Ring1][#Branch1][=O]", "[C][C][Branch1][C][C][Branch1][C][C][O][C][=Branch1][C][=O][N][C][C][C][Branch1][Branch1][C][C][Ring1][=Branch1][C][=Branch1][C][=O][N][Branch1][#Branch1][C][C][=Branch1][C][=O][O][C][N][Ring1][N][C][=C][C][=C][C][=C][Ring1][=Branch1]" ], "smiles": [ "COC(=O)CN1CN(c2ccccc2)C2(CCN(C(=O)OC(C)(C)C)CC2)C1=O", "CC(C)(C)OC(=O)N1CCC2(CC1)C(=O)N(CC(=O)O)CN2c1ccccc1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>>><molecule_2d> Please propose potential solvents that might have been utilized in the provided chemical reaction.", "role": "user" }, { "content": "Sure. A potential answer could be: O .", "role": "assistant" } ]

{ "selfies": [ "[C][C][C][Branch1][C][C][C][C][=C][C][=C][Branch1][=N][C][=C][C][=C][Branch1][Ring1][O][C][C][=C][Ring1][Branch2][C][=C][Ring1][=C]", "[C][C][C][Branch1][C][C][C][C][=C][C][=C][Branch1][N][C][=C][C][=C][Branch1][C][O][C][=C][Ring1][#Branch1][C][=C][Ring1][=N]" ], "smiles": [ "CCC(C)Cc1ccc(-c2ccc(OC)cc2)cc1", "CCC(C)Cc1ccc(-c2ccc(O)cc2)cc1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given the following chemical reaction <molecule_2d>>><molecule_2d>, what are some potential solvents that could have been employed?", "role": "user" }, { "content": "ClCCl .", "role": "assistant" } ]

{ "selfies": [ "[C][C][=N][C][Branch1][=Branch2][N][C][C][O][C][C][Ring1][=Branch1][=C][C][=C][Ring1][N][N+1][=Branch1][C][=O][O-1]", "[C][C][=N][C][Branch1][=Branch2][N][C][C][O][C][C][Ring1][=Branch1][=C][C][=C][Ring1][N][N]" ], "smiles": [ "Cc1nc(N2CCOCC2)ccc1[N+](=O)[O-]", "Cc1nc(N2CCOCC2)ccc1N" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>>><molecule_2d> From the provided chemical reaction, propose some possible solvents that could have been used.", "role": "user" }, { "content": "CCO.O .", "role": "assistant" } ]

{ "selfies": [ "[C][C][=Branch1][C][=O][N][C][=C][C][=C][Branch2][Ring1][Ring1][S][=Branch1][C][=O][=Branch1][C][=O][N][C][C][C][=C][C][=C][C][=C][Ring1][=Branch1][C][=C][Ring2][Ring1][C]", "[N][C][=C][C][=C][Branch2][Ring1][Ring1][S][=Branch1][C][=O][=Branch1][C][=O][N][C][C][C][=C][C][=C][C][=C][Ring1][=Branch1][C][=C][Ring2][Ring1][C]" ], "smiles": [ "CC(=O)Nc1ccc(S(=O)(=O)NCCc2ccccc2)cc1", "Nc1ccc(S(=O)(=O)NCCc2ccccc2)cc1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>>><molecule_2d> From the provided chemical reaction, propose some possible solvents that could have been used.", "role": "user" }, { "content": "C1COCCO1 .", "role": "assistant" } ]

{ "selfies": [ "[C][N][C][C][N][Branch1][C][C][C][=Branch1][C][=O][O][C][Branch1][#Branch2][C][C][=C][C][=C][C][=C][Ring1][=Branch1][C][=Branch1][C][=O][O][C]", "[O][=C][Branch1][C][Cl][N][C][C][O][C][C][Ring1][=Branch1]", "[C][O][C][=Branch1][C][=O][C][Branch1][#Branch2][C][C][=C][C][=C][C][=C][Ring1][=Branch1][O][C][=Branch1][C][=O][N][Branch1][C][C][C][C][N][Branch1][C][C][C][=Branch1][C][=O][N][C][C][O][C][C][Ring1][=Branch1]" ], "smiles": [ "CNCCN(C)C(=O)OC(Cc1ccccc1)C(=O)OC", "O=C(Cl)N1CCOCC1", "COC(=O)C(Cc1ccccc1)OC(=O)N(C)CCN(C)C(=O)N1CCOCC1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given the following reaction <molecule_2d>.<molecule_2d>>><molecule_2d>, what are some possible solvents that could have been utilized?", "role": "user" }, { "content": "ClCCl .", "role": "assistant" } ]

{ "selfies": [ "[C][C][=Branch1][C][=O][C][=C][C][=C][C][Branch1][=Branch1][N+1][=Branch1][C][=O][O-1][=C][Ring1][=Branch2][O]", "[C][I]", "[C][O][C][=C][Branch1][=Branch1][C][Branch1][C][C][=O][C][=C][C][=C][Ring1][=Branch2][N+1][=Branch1][C][=O][O-1]" ], "smiles": [ "CC(=O)c1cccc([N+](=O)[O-])c1O", "CI", "COc1c(C(C)=O)cccc1[N+](=O)[O-]" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given this chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>, what are some solvents that could have been used?", "role": "user" }, { "content": "CN(C)C=O .", "role": "assistant" } ]

{ "selfies": [ "[Cl][C][C][C][Br]", "[O][C][C][C][C][C][N][C][C][Ring1][=Branch1]", "[O][C][C][C][C][C][N][Branch1][Branch1][C][C][C][Cl][C][C][Ring1][#Branch2]" ], "smiles": [ "ClCCCBr", "OCCC1CCNCC1", "OCCC1CCN(CCCCl)CC1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Please suggest some possible solvents that could have been used in the following chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>.", "role": "user" }, { "content": "CC(C)=O .", "role": "assistant" } ]

{ "selfies": [ "[C][C][=C][C][=C][Branch1][=Branch1][C][=Branch1][C][=O][O][C][Branch1][C][N][=C][Ring1][#Branch2]", "[O][=C][Branch1][=C][O][C][=Branch1][C][=O][C][Branch1][C][F][Branch1][C][F][F][C][Branch1][C][F][Branch1][C][F][F]", "[C][C][=C][C][=C][Branch1][=Branch1][C][=Branch1][C][=O][O][C][Branch1][=C][N][C][=Branch1][C][=O][C][Branch1][C][F][Branch1][C][F][F][=C][Ring1][S]" ], "smiles": [ "Cc1ccc(C(=O)O)c(N)c1", "O=C(OC(=O)C(F)(F)F)C(F)(F)F", "Cc1ccc(C(=O)O)c(NC(=O)C(F)(F)F)c1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>.<molecule_2d>>><molecule_2d> Please propose potential solvents that might have been utilized in the provided chemical reaction.", "role": "user" }, { "content": "Sure. A potential answer could be: C1COCCO1 .", "role": "assistant" } ]

{ "selfies": [ "[O][=C][Branch2][Ring1][=Branch1][N][C][=N][C][=C][C][=C][Branch1][=Branch1][N+1][=Branch1][C][=O][O-1][C][=C][Ring1][=Branch2][S][Ring1][N][C][=C][C][=C][C][=C][Ring1][=Branch1]", "[N][C][=C][C][=C][N][=C][Branch1][=C][N][C][=Branch1][C][=O][C][=C][C][=C][C][=C][Ring1][=Branch1][S][C][Ring1][=C][=C][Ring2][Ring1][C]" ], "smiles": [ "O=C(Nc1nc2ccc([N+](=O)[O-])cc2s1)c1ccccc1", "Nc1ccc2nc(NC(=O)c3ccccc3)sc2c1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Can you suggest some solvents that might have been used in the given chemical reaction? <molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "A probable solvent could be CCOC(C)=O .", "role": "assistant" } ]

{ "selfies": [ "[Cl][C][C][N][C][C][C][C][Ring1][Branch1]", "[O][C][=C][C][=C][Branch2][Ring1][S][C][=Branch2][Ring1][Ring2][=C][Branch1][=Branch2][C][=C][C][=C][C][=C][Ring1][=Branch1][C][Branch1][C][F][Branch1][C][F][F][C][=C][C][=C][C][=C][Ring1][=Branch1][C][=C][Ring2][Ring1][Branch2]", "[F][C][Branch1][C][F][Branch1][C][F][C][=Branch2][Ring1][S][=C][Branch1][=Branch2][C][=C][C][=C][C][=C][Ring1][=Branch1][C][=C][C][=C][Branch1][O][O][C][C][N][C][C][C][C][Ring1][Branch1][C][=C][Ring1][=C][C][=C][C][=C][C][=C][Ring1][=Branch1]" ], "smiles": [ "ClCCN1CCCC1", "Oc1ccc(C(=C(c2ccccc2)C(F)(F)F)c2ccccc2)cc1", "FC(F)(F)C(=C(c1ccccc1)c1ccc(OCCN2CCCC2)cc1)c1ccccc1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>.<molecule_2d>>><molecule_2d> Please propose potential solvents that might have been utilized in the provided chemical reaction.", "role": "user" }, { "content": "Sure. A potential answer could be: Cc1ccccc1C .", "role": "assistant" } ]

{ "selfies": [ "[C][C][Branch1][C][C][Branch1][C][C][C][=C][C][=C][Branch1][C][N][C][Branch1][C][N][=C][Ring1][Branch2]", "[C][C][N][Branch2][Branch1][=Branch2][C][C][C][C][Branch2][Ring2][C][N][C][=C][C][=C][Branch1][P][N][C][C][=C][C][=C][Branch1][Ring1][O][C][C][=C][Ring1][Branch2][O][C][N][=C][N][=C][Ring2][Ring1][C][Ring2][Ring1][Branch1][C][O][C][Branch1][C][C][Branch1][C][C][O][C][Ring2][Ring1][#C][Ring1][#Branch1][C][C][C][Branch1][Branch2][C][C][C][=Branch1][C][=O][O][C][Ring1][=Branch2]", "[C][C][N][Branch2][Branch1][=Branch2][C][C][C][C][Branch2][Ring2][C][N][C][=C][C][=C][Branch1][P][N][C][C][=C][C][=C][Branch1][Ring1][O][C][C][=C][Ring1][Branch2][O][C][N][=C][N][=C][Ring2][Ring1][C][Ring2][Ring1][Branch1][C][O][C][Branch1][C][C][Branch1][C][C][O][C][Ring2][Ring1][#C][Ring1][#Branch1][C][C][C][Branch2][Ring1][O][C][C][C][=Branch1][C][=O][N][C][=C][C][=C][Branch1][=Branch2][C][Branch1][C][C][Branch1][C][C][C][C][=C][Ring1][#Branch2][N][C][Ring2][Ring1][Ring2]" ], "smiles": [ "CC(C)(C)c1ccc(N)c(N)c1", "CCN(CC1CC(n2ccc3c(NCc4ccc(OC)cc4OC)ncnc32)C2OC(C)(C)OC12)C1CC(CCC(=O)O)C1", "CCN(CC1CC(n2ccc3c(NCc4ccc(OC)cc4OC)ncnc32)C2OC(C)(C)OC12)C1CC(CCC(=O)Nc2ccc(C(C)(C)C)cc2N)C1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "What solvents could have been utilized in the following chemical reaction? <molecule_2d>.<molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "CN(C)C=O .", "role": "assistant" } ]

{ "selfies": [ "[C][C][=C][Branch1][#Branch1][C][C][=Branch1][C][=O][O][C][=C][C][=C][C][Branch1][C][F][=C][C][Ring1][#Branch1][=C][Ring1][#C][C][=Branch1][C][=O][C][=C][C][=C][Branch1][=Branch2][S][Branch1][C][C][=Branch1][C][=O][=O][C][=C][Ring1][#Branch2]", "[C][C][=C][Branch1][#Branch1][C][C][=Branch1][C][=O][O][C][=C][C][=C][C][Branch1][C][F][=C][C][Ring1][#Branch1][=C][Ring1][#C][C][Branch1][C][O][C][=C][C][=C][Branch1][=Branch2][S][Branch1][C][C][=Branch1][C][=O][=O][C][=C][Ring1][#Branch2]" ], "smiles": [ "Cc1c(CC(=O)O)cc2ccc(F)cc2c1C(=O)c1ccc(S(C)(=O)=O)cc1", "Cc1c(CC(=O)O)cc2ccc(F)cc2c1C(O)c1ccc(S(C)(=O)=O)cc1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given the following reaction <molecule_2d>>><molecule_2d>, what are some possible solvents that could have been utilized?", "role": "user" }, { "content": "CO .", "role": "assistant" } ]

{ "selfies": [ "[C][C][I]", "[O][C][=C][C][=C][Branch1][C][Br][C][Branch1][C][Cl][=C][Ring1][Branch2]", "[C][C][O][C][=C][C][=C][Branch1][C][Br][C][Branch1][C][Cl][=C][Ring1][Branch2]" ], "smiles": [ "CCI", "Oc1ccc(Br)c(Cl)c1", "CCOc1ccc(Br)c(Cl)c1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Can you provide potential solvents for the following chemical reaction? <molecule_2d>.<molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "C1CCOC1 .", "role": "assistant" } ]

{ "selfies": [ "[C][O][C][=C][C][Branch1][=Branch1][N+1][=Branch1][C][=O][O-1][=C][C][=C][Ring1][=Branch2][F]", "[O][C][=C][C][=C][Branch1][C][Cl][C][Branch1][C][Cl][=C][Ring1][Branch2]", "[C][O][C][=C][C][Branch1][=Branch1][N+1][=Branch1][C][=O][O-1][=C][C][=C][Ring1][=Branch2][O][C][=C][C][=C][Branch1][C][Cl][C][Branch1][C][Cl][=C][Ring1][Branch2]" ], "smiles": [ "COc1cc([N+](=O)[O-])ccc1F", "Oc1ccc(Cl)c(Cl)c1", "COc1cc([N+](=O)[O-])ccc1Oc1ccc(Cl)c(Cl)c1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>.<molecule_2d>>><molecule_2d> Based on the given chemical reaction, can you propose some likely solvents that might have been utilized?", "role": "user" }, { "content": "A possible solvent can be O .", "role": "assistant" } ]

{ "selfies": [ "[C][O][C][=C][C][=C][Branch1][Ring1][O][C][C][Branch1][=Branch1][C][=Branch1][C][=O][O][=C][Ring1][O][F]", "[O][=S][Branch1][C][Cl][Cl]", "[C][O][C][=C][C][=C][Branch1][Ring1][O][C][C][Branch1][=Branch1][C][=Branch1][C][=O][Cl][=C][Ring1][O][F]" ], "smiles": [ "COc1ccc(OC)c(C(=O)O)c1F", "O=S(Cl)Cl", "COc1ccc(OC)c(C(=O)Cl)c1F" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>.<molecule_2d>>><molecule_2d> Based on the given chemical reaction, can you propose some likely solvents that might have been utilized?", "role": "user" }, { "content": "A possible solvent can be ClCCl .", "role": "assistant" } ]

{ "selfies": [ "[C][C][O][C][=Branch1][C][=O][C][=C][Branch1][=Branch2][C][=C][C][=C][C][=C][Ring1][=Branch1][C][=C][C][Branch1][C][Cl][=C][C][=C][Ring1][#Branch1][NH1][C][Ring1][P][=O]", "[C][I]", "[C][C][O][C][=Branch1][C][=O][C][=C][Branch1][=Branch2][C][=C][C][=C][C][=C][Ring1][=Branch1][C][=C][C][Branch1][C][Cl][=C][C][=C][Ring1][#Branch1][N][Branch1][C][C][C][Ring2][Ring1][C][=O]" ], "smiles": [ "CCOC(=O)c1c(-c2ccccc2)c2cc(Cl)ccc2[nH]c1=O", "CI", "CCOC(=O)c1c(-c2ccccc2)c2cc(Cl)ccc2n(C)c1=O" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>.<molecule_2d>>><molecule_2d> Based on the given chemical reaction, can you propose some likely solvents that might have been utilized?", "role": "user" }, { "content": "A possible solvent can be CN(C)C=O .", "role": "assistant" } ]

{ "selfies": [ "[C][O][C][=Branch1][C][=O][C][Branch1][C][C][Branch1][C][C][C][N][C][=Branch1][C][=O][C][=N][C][Branch1][Ring1][C][#N][=C][C][Branch2][Ring1][=N][C][=C][Branch1][=Branch2][C][=C][C][=C][C][=C][Ring1][=Branch1][C][=Branch1][C][=O][N][Ring1][=N][C][C][=C][C][=C][C][=C][Ring1][=Branch1][=C][Ring2][Ring1][#Branch2][O]", "[C][C][Branch1][C][C][Branch2][Branch1][Ring2][C][N][C][=Branch1][C][=O][C][=N][C][Branch1][Ring1][C][#N][=C][C][Branch2][Ring1][=N][C][=C][Branch1][=Branch2][C][=C][C][=C][C][=C][Ring1][=Branch1][C][=Branch1][C][=O][N][Ring1][=N][C][C][=C][C][=C][C][=C][Ring1][=Branch1][=C][Ring2][Ring1][#Branch2][O][C][=Branch1][C][=O][O]" ], "smiles": [ "COC(=O)C(C)(C)CNC(=O)c1nc(C#N)c2c(cc(-c3ccccc3)c(=O)n2Cc2ccccc2)c1O", "CC(C)(CNC(=O)c1nc(C#N)c2c(cc(-c3ccccc3)c(=O)n2Cc2ccccc2)c1O)C(=O)O" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Can you suggest some solvents that might have been used in the given chemical reaction? <molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "A probable solvent could be CO .", "role": "assistant" } ]

{ "selfies": [ "[C][N][Branch1][C][C][C][C][C][C][C][C][C][C][C][C][C][N][C][=Branch1][C][=O][C][=C][C][=C][C][=C][Ring1][=Branch1][C][Ring1][#Branch2][=O]", "[C][N][Branch1][C][C][C][C][C][C][C][C][C][C][C][C][C][N]" ], "smiles": [ "CN(C)CCCCCCCCCCCN1C(=O)c2ccccc2C1=O", "CN(C)CCCCCCCCCCCN" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given this chemical reaction <molecule_2d>>><molecule_2d>, what are some solvents that could have been used?", "role": "user" }, { "content": "CCO.Cl .", "role": "assistant" } ]

{ "selfies": [ "[C][O][C][=C][C][=C][Branch2][Ring1][=Branch1][C][=N][C][C][Branch1][C][O][C][Branch1][=Branch2][C][=C][C][=C][C][=C][Ring1][=Branch1][O][Ring1][=N][C][=C][Ring2][Ring1][Ring1]", "[O][=C][=N][C][=C][C][=C][C][=C][Ring1][=Branch1]", "[C][O][C][=C][C][=C][Branch2][Ring2][Ring2][C][=N][C][C][Branch1][#C][O][C][=Branch1][C][=O][N][C][=C][C][=C][C][=C][Ring1][=Branch1][C][Branch1][=Branch2][C][=C][C][=C][C][=C][Ring1][=Branch1][O][Ring2][Ring1][=Branch1][C][=C][Ring2][Ring1][N]" ], "smiles": [ "COc1ccc(C2=NCC(O)C(c3ccccc3)O2)cc1", "O=C=Nc1ccccc1", "COc1ccc(C2=NCC(OC(=O)Nc3ccccc3)C(c3ccccc3)O2)cc1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given this chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>, what are some solvents that could have been used?", "role": "user" }, { "content": "ClCCCl .", "role": "assistant" } ]

{ "selfies": [ "[C][C][Branch1][C][C][Branch1][C][C][O][C][=Branch1][C][=O][N][C][C][C][Branch1][S][O][C][=C][C][Branch1][C][F][=C][C][Branch1][C][Br][=C][Ring1][Branch2][C][C][Ring1][#C]", "[C][N][Branch1][C][C][C][=O]", "[C][C][Branch1][C][C][Branch1][C][C][O][C][=Branch1][C][=O][N][C][C][C][Branch1][P][O][C][=C][C][Branch1][C][F][=C][C][Branch1][Ring1][C][=O][=C][Ring1][=Branch2][C][C][Ring1][S]" ], "smiles": [ "CC(C)(C)OC(=O)N1CCC(Oc2cc(F)cc(Br)c2)CC1", "CN(C)C=O", "CC(C)(C)OC(=O)N1CCC(Oc2cc(F)cc(C=O)c2)CC1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given this chemical reaction <molecule_2d>.<molecule_2d>>><molecule_2d>, what are some solvents that could have been used?", "role": "user" }, { "content": "C1CCOC1 .", "role": "assistant" } ]

{ "selfies": [ "[C][C][C][N][C][=C][Branch2][Ring1][C][C][=C][C][Branch1][=Branch1][N+1][=Branch1][C][=O][O-1][=C][C][=C][Ring1][=Branch2][Ring1][N][C][C][C][C][Ring1][#C]", "[C][C][C][N][C][=C][Branch1][=C][C][=C][C][Branch1][C][N][=C][C][=C][Ring1][#Branch1][Ring1][#Branch2][C][C][C][C][Ring1][=N]" ], "smiles": [ "CCCn1c2c(c3cc([N+](=O)[O-])ccc31)CCCC2", "CCCn1c2c(c3cc(N)ccc31)CCCC2" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "What solvents could have been utilized in the following chemical reaction? <molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "CCOC(C)=O .", "role": "assistant" } ]

{ "selfies": [ "[C][C][Branch1][C][C][Branch1][C][C][O][C][=Branch1][C][=O][N][C][C][C][Br]", "[N][C][=Branch1][C][=O][C][=C][Branch2][Ring1][C][N][C][=Branch1][C][=O][N][C][=C][C][=C][Branch1][C][Cl][C][=C][Ring1][#Branch1][S][C][=C][Ring1][S][C][C][N][C][Ring1][=Branch1]", "[C][C][Branch1][C][C][Branch1][C][C][O][C][=Branch1][C][=O][N][C][C][C][N][C][C][C][=C][Branch2][Ring1][#C][S][C][Branch2][Ring1][C][N][C][=Branch1][C][=O][N][C][=C][C][=C][Branch1][C][Cl][C][=C][Ring1][#Branch1][=C][Ring1][S][C][Branch1][C][N][=O][C][Ring2][Ring1][#Branch1]" ], "smiles": [ "CC(C)(C)OC(=O)NCCCBr", "NC(=O)c1c(NC(=O)Nc2ccc(Cl)cc2)sc2c1CCNC2", "CC(C)(C)OC(=O)NCCCN1CCc2c(sc(NC(=O)Nc3ccc(Cl)cc3)c2C(N)=O)C1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Can you suggest some solvents that might have been used in the given chemical reaction? <molecule_2d>.<molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "A probable solvent could be CN(C)C=O .", "role": "assistant" } ]

{ "selfies": [ "[C][C][Branch1][C][C][N][Branch1][C][C][C][C][=C][C][=C][C][=C][Ring1][=Branch1][C][C][Ring1][=Branch2][O]", "[O][=C][Branch1][C][Cl][C][Cl]", "[C][C][Branch1][C][C][N][Branch1][C][C][C][C][=C][C][=C][C][=C][Ring1][=Branch1][C][C][Ring1][=Branch2][O][C][=Branch1][C][=O][C][Cl]" ], "smiles": [ "CC(C)N(C)C1c2ccccc2CC1O", "O=C(Cl)CCl", "CC(C)N(C)C1c2ccccc2CC1OC(=O)CCl" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>.<molecule_2d>>><molecule_2d> Please propose potential solvents that might have been utilized in the provided chemical reaction.", "role": "user" }, { "content": "Sure. A potential answer could be: ClCCl.O .", "role": "assistant" } ]

{ "selfies": [ "[C][N][Branch1][C][C][C][C][O][C][=C][C][=C][Branch1][=Branch1][N+1][=Branch1][C][=O][O-1][C][=N][Ring1][=Branch2]", "[C][N][Branch1][C][C][C][C][O][C][=C][C][=C][Branch1][C][N][C][=N][Ring1][#Branch1]" ], "smiles": [ "CN(C)CCOc1ccc([N+](=O)[O-])cn1", "CN(C)CCOc1ccc(N)cn1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given the following reaction <molecule_2d>>><molecule_2d>, what are some possible solvents that could have been utilized?", "role": "user" }, { "content": "CO .", "role": "assistant" } ]

{ "selfies": [ "[C][C][C][C][Branch1][#Branch1][C][=Branch1][C][=O][O][C][C][=C][Branch1][C][C][N][=C][Branch1][=Branch2][N][C][C][C][C][C][Ring1][=Branch1][N][=C][Ring1][=N][N][C][C][C][C][C][Ring1][=Branch1]", "[C][C][C][C][Branch1][=Branch1][C][=Branch1][C][=O][O][C][=C][Branch1][C][C][N][=C][Branch1][=Branch2][N][C][C][C][C][C][Ring1][=Branch1][N][=C][Ring1][=N][N][C][C][C][C][C][Ring1][=Branch1]" ], "smiles": [ "CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1N1CCCCC1", "CCCC(C(=O)O)c1c(C)nc(N2CCCCC2)nc1N1CCCCC1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>>><molecule_2d> Please propose potential solvents that might have been utilized in the provided chemical reaction.", "role": "user" }, { "content": "Sure. A potential answer could be: CO .", "role": "assistant" } ]

{ "selfies": [ "[O][=N+1][Branch1][C][O-1][C][=C][C][=C][N][=C][NH1][C][Ring1][Branch1][=C][Ring1][=Branch2]", "[N][C][=C][C][=C][N][=C][NH1][C][Ring1][Branch1][=C][Ring1][=Branch2]" ], "smiles": [ "O=[N+]([O-])c1ccc2nc[nH]c2c1", "Nc1ccc2nc[nH]c2c1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Can you provide potential solvents for the following chemical reaction? <molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "C1CCOC1 .", "role": "assistant" } ]

{ "selfies": [ "[C][#C][C][C][Branch1][=N][C][=C][C][=C][Branch1][C][Cl][C][=C][Ring1][#Branch1][Cl][C][Branch1][C][O][Branch1][=Branch1][C][Branch1][C][C][=O][C][=C][C][=C][N][=C][Ring1][=Branch1]", "[C][#C][C][C][Branch1][=N][C][=C][C][=C][Branch1][C][Cl][C][=C][Ring1][#Branch1][Cl][C][Branch1][C][O][Branch1][=Branch2][C][=C][C][=C][N][=C][Ring1][=Branch1][C][Branch1][C][C][O]" ], "smiles": [ "C#CCC(c1ccc(Cl)cc1Cl)C(O)(C(C)=O)c1cccnc1", "C#CCC(c1ccc(Cl)cc1Cl)C(O)(c1cccnc1)C(C)O" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Please provide possible solvents based on the following chemical reaction <molecule_2d>>><molecule_2d>.", "role": "user" }, { "content": "CCO .", "role": "assistant" } ]

{ "selfies": [ "[C][C][=C][C][=C][Branch1][=Branch1][C][=C][Ring1][=Branch1][Br][NH1][C][=Branch1][C][=O][N][Ring1][=Branch2][C][C][C][N][C][C][Ring1][=Branch1]", "[O][=C][C][C][O][C][C][Ring1][=Branch1]", "[C][C][=C][C][=C][Branch1][=Branch1][C][=C][Ring1][=Branch1][Br][NH1][C][=Branch1][C][=O][N][Ring1][=Branch2][C][C][C][N][Branch1][=Branch2][C][C][C][O][C][C][Ring1][=Branch1][C][C][Ring1][N]" ], "smiles": [ "Cc1cc2c(cc1Br)[nH]c(=O)n2C1CCNCC1", "O=C1CCOCC1", "Cc1cc2c(cc1Br)[nH]c(=O)n2C1CCN(C2CCOCC2)CC1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given the following reaction <molecule_2d>.<molecule_2d>>><molecule_2d>, what are some possible solvents that could have been utilized?", "role": "user" }, { "content": "ClCCl .", "role": "assistant" } ]

{ "selfies": [ "[O][=C][C][=C][Branch1][C][O][C][=C][C][=C][C][Branch1][C][Br][=C][C][=C][Ring1][N][Ring1][#Branch1]", "[O][=S][=Branch1][C][=O][Branch2][Ring1][O][N][Branch1][=Branch2][C][=C][C][=C][C][=C][Ring1][=Branch1][S][=Branch1][C][=O][=Branch1][C][=O][C][Branch1][C][F][Branch1][C][F][F][C][Branch1][C][F][Branch1][C][F][F]", "[O][=C][C][=C][Branch1][P][O][S][=Branch1][C][=O][=Branch1][C][=O][C][Branch1][C][F][Branch1][C][F][F][C][=C][C][=C][C][Branch1][C][Br][=C][C][=C][Ring2][Ring1][Ring1][Ring1][#Branch1]" ], "smiles": [ "O=Cc1c(O)ccc2cc(Br)ccc12", "O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F", "O=Cc1c(OS(=O)(=O)C(F)(F)F)ccc2cc(Br)ccc12" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Can you suggest some solvents that might have been used in the given chemical reaction? <molecule_2d>.<molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "A probable solvent could be ClCCl .", "role": "assistant" } ]

{ "selfies": [ "[C][O][C][=Branch1][C][=O][C][=C][C][=C][Branch1][C][Cl][C][=C][C][=C][Ring1][#Branch1][S][Ring1][#Branch2]", "[O][=C][Branch1][C][O][C][=C][C][=C][Branch1][C][Cl][C][=C][C][=C][Ring1][#Branch1][S][Ring1][#Branch2]" ], "smiles": [ "COC(=O)c1cc2c(Cl)cccc2s1", "O=C(O)c1cc2c(Cl)cccc2s1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "<molecule_2d>>><molecule_2d> Please propose potential solvents that might have been utilized in the provided chemical reaction.", "role": "user" }, { "content": "Sure. A potential answer could be: CO.O .", "role": "assistant" } ]

{ "selfies": [ "[O][C][C][=C][C][=C][NH1][N][=N][C][Ring1][Branch1][=C][Ring1][=Branch2]", "[O][=C][C][=C][C][=C][NH1][N][=N][C][Ring1][Branch1][=C][Ring1][=Branch2]" ], "smiles": [ "OCc1ccc2[nH]nnc2c1", "O=Cc1ccc2[nH]nnc2c1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Given the following chemical reaction <molecule_2d>>><molecule_2d>, what are some potential solvents that could have been employed?", "role": "user" }, { "content": "CC(C)=O .", "role": "assistant" } ]

{ "selfies": [ "[C][C][C][C][C][Branch1][Ring1][C][O][C][=C][C][=C][C][=Branch1][Ring2][=C][Ring1][=Branch1][O][C][O][Ring1][=Branch1]", "[C][S][=Branch1][C][=O][=Branch1][C][=O][Cl]", "[C][C][C][C][C][Branch1][O][C][O][S][Branch1][C][C][=Branch1][C][=O][=O][C][=C][C][=C][C][=Branch1][Ring2][=C][Ring1][=Branch1][O][C][O][Ring1][=Branch1]" ], "smiles": [ "CCCCC(CO)c1ccc2c(c1)OCO2", "CS(=O)(=O)Cl", "CCCCC(COS(C)(=O)=O)c1ccc2c(c1)OCO2" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Can you provide potential solvents for the following chemical reaction? <molecule_2d>.<molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "ClCCl .", "role": "assistant" } ]

{ "selfies": [ "[C][O][C][=Branch1][C][=O][C][C][=C][C][=C][Branch1][P][C][=C][C][=C][C][NH1][N][=C][Branch1][C][N][C][Ring1][#Branch2][=Ring1][=Branch1][C][=C][Ring1][S]", "[N][C][=N][NH1][C][=C][C][=C][C][Branch1][P][C][=C][C][=C][Branch1][#Branch1][C][C][=Branch1][C][=O][O][C][=C][Ring1][#Branch2][=C][Ring2][Ring1][Ring1][Ring1][S]" ], "smiles": [ "COC(=O)Cc1ccc(-c2cccc3[nH]nc(N)c23)cc1", "Nc1n[nH]c2cccc(-c3ccc(CC(=O)O)cc3)c12" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Can you suggest some solvents that might have been used in the given chemical reaction? <molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "A probable solvent could be CO .", "role": "assistant" } ]

{ "selfies": [ "[C][C][Branch1][C][O][C][C][N][Branch1][#Branch2][C][C][=C][C][=C][C][=C][Ring1][=Branch1][C][C][N][Ring1][=N][C][C][=C][C][=C][C][=C][Ring1][=Branch1]", "[C][I]", "[C][O][C][Branch1][C][C][C][C][N][Branch1][#Branch2][C][C][=C][C][=C][C][=C][Ring1][=Branch1][C][C][N][Ring1][=N][C][C][=C][C][=C][C][=C][Ring1][=Branch1]" ], "smiles": [ "CC(O)C1CN(Cc2ccccc2)CCN1Cc1ccccc1", "CI", "COC(C)C1CN(Cc2ccccc2)CCN1Cc1ccccc1" ] }

[ { "content": "You are a chemist. Now you are given a reaction equation. Please predict the possible solvents of the reaction. The reaction equation has the following format:\n```\nreactant1.reactant2. ... .reactantN>>product\n```\nYour task is to predict the structure representation of the solvents. We provide the SMILES of the reactions.", "role": "system" }, { "content": "Can you provide potential solvents for the following chemical reaction? <molecule_2d>.<molecule_2d>>><molecule_2d>", "role": "user" }, { "content": "CN(C)C=O .", "role": "assistant" } ]