Gender identity plays a potentially important role contributing to HIV risk among MSM in South Africa. Where studies have included a focus on gender identity, MSM reporting gender non-conformity have been found to have a ...

Modern advances in genomics provide an opportunity to reinterpret historical bacterial culture collections. In this study, genotypic antibiotic resistance profiles of Mycobacterium tuberculosis isolates from a historical ...

The worldwide proliferation of life-threatening metallo-β-lactamase (MBLs)-producing Gram-negative bacteria is a serious concern to public health. MBLs are compromising the therapeutic efficacies of β-lactams, particularly ...

This study from South Africa highlights the importance of rectal Trichomonas vaginalis infection as a sexually transmitted infection among men who have sex with men (MSM). We report seven MSM presenting with rectal T. ...

Recently, NIH has funded a center for autophagy research named the Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence, located at the University of New Mexico Health Science Center (UNM ...

Bacterial vaginosis (BV) and genital mycoplasmas are infections of the reproductive tract that play important roles in maternal and foetal health. Genital mycoplasmas include Mycoplasma genitalium, M. hominis, Ureaplasma ...

Staphylococcus aureus (S. aureus) is one of the leading causes of human diseases in hospital and community settings. Methicillin resistant Staphylococcus aureus (MRSA) has emerged as a significant problem worldwide, resisting ...

Enterococcus faecalis is a lactic acid-producing Gram-positive bacterium
commonly found in the intestinal tract of humans and animals; it is implicated in
multidrug-resistant nosocomial infections. The draft genome of ...

Chlamydia trachomatis and Neisseria gonorrhoeae constitute major public health problems among women, but the burden of infection in sub-Saharan Africa is poorly documented. We conducted a structured review of the prevalence ...

BACKGROUND : Rapid and accurate diagnosis of neonatal sepsis is highly warranted because of high associated
morbidity and mortality. The aim of this study was to evaluate the performance of a novel multiplex PCR assay ...

BACKGROUND : In many countries, regular monitoring of the emergence of resistance to anti-tuberculosis drugs is
hampered by the limitations of phenotypic testing for drug susceptibility. We therefore evaluated the use ...

BACKGROUND : Globally, per-capita, South Africa reports a disproportionately high number of cases of multidrug-resistant (MDR) tuberculosis and extensively drug-resistant (XDR) tuberculosis. We sought to estimate the ...

BACKGROUND : The incidence of multidrug-resistant tuberculosis (MDR-TB) is increasing and the emergence of
extensively drug-resistant tuberculosis (XDR-TB) is a major challenge. Controlling resistance, reducing transmission
and ...

We describe here the draft genome sequence of a Mycobacterium goodii
isolate from a pediatric patient in Western Cape, South Africa. To our knowledge,
this is the second reported genome of this rapidly growing nontuberculous ...

We compared the proportion of cases of community-associated and healthcare-associated methicillin-resistant Staphylococcus aureus (CA-MRSA and HA-MRSA, respectively) bacteraemia among patients at five hospitals in the ...