def _point_mutation(individual, idx, random_state):
    """Apply a point mutation on individual at position idx

    Args:
        individual: instance of Base
        idx: index
        random_state: an instance of np.random.RandomState

    Returns:
        mutated individual
    """
    el, c, r, lst = individual.mapping[idx]
    gene = lst[r]
    if isinstance(gene, list):
        new_gene = gene[:]
        j = random_state.randint(0, len(gene))
        if j == 0:
            choices = individual.pset.operators[:]
            if len(choices) > 1:
                prim = individual.pset.mapping[gene[j]]
                choices.pop(choices.index(prim))
            new_j = individual.pset.imapping[random_state.choice(choices)]
        else:
            valid_inputs = individual._valid_inputs[idx][:]
            if len(valid_inputs) > 1:
                valid_inputs.pop(valid_inputs.index(gene[j]))
            new_j = random_state.choice(valid_inputs)
        new_gene[j] = new_j
    else:
        new_gene = random_state.randint(0, len(individual) - individual.
            n_out - 1)
    new_individual = individual.clone()
    new_individual[idx] = new_gene
    return new_individual
