def is_negate(trial_value):
    """
    Example: !EGFR => (True, EGFR)

    :param trial_value:
    :return:
    """
    negate = (True if trial_value.__class__ is str and trial_value and 
        trial_value[0] == '!' else False)
    trial_value = trial_value[1:] if negate else trial_value
    return trial_value, negate
