def remove_duplicates(list_of_tuples):
    """
    Takes a list of tuples and removes duplicate entries.
    Reverses the pairs (0, 1, 2, 3) to (2, 3, 0, 1) for comparison.
    :param list_of_tuples: [(0, 1, 2, 3), (2, 3, 0, 1)]
    :return: List of unique tuples.
    """
    reduced = set()
    for i in list_of_tuples:
        if not (i[2], i[3], i[0], i[1]) in reduced:
            reduced.add(i)
    return list(reduced)
