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# AMR prediction with LGBMClassifier models
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This repository contains a Python script for predicting antimicrobial resistance (AMR) using the LGBMClassifier model. The script reads input datasets from a directory, applies feature extraction techniques to obtain k-mer features, trains and tests the models using cross-validation, and outputs the results in text files.
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![Retrospectives](https://user-images.githubusercontent.com/43249674/224884310-71214a69-3f27-4628-ad21-bb34c6daac45.jpg)
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## Getting Started
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These instructions will get you a copy of the project up and running on your local machine for development and testing purposes.
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### Prerequisites
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This script requires the following Python libraries:
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pandas
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scikit-learn
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numpy
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tqdm
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lightgbm
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hyperopt
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joblib
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bayesian-optimization
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skopt
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### Installing
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Clone the repository to your local machine and install the required libraries:
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```bash
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$ git clone https://github.com/username/repo.git
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$ cd repo
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$ pip install -r requirements.txt
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```
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### Usage
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To use the script, execute the following command:
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css
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Copy code
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```bash
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$ python main.py
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```
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## Code Structure
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The main script consists of several sections:
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1 Import necessary libraries
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2 Set seed for reproducibility
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3 Define function to get list of models to evaluate
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4 Load list of selected samples
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5 Call function to get list of models
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6 Initialize KFold cross-validation
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7 Iterate over values of k to read the corresponding k-mer feature dataset
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8 Iterate over the models list
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9 Write results to text file
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## Data Description
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The input datasets are CSV files containing bacterial genomic sequences and their corresponding resistance profiles for selected antibiotics. The script reads these files from a directory and applies k-mer feature extraction techniques to obtain numerical feature vectors.
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## Models
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The script uses two models for AMR prediction: Random Forest and LGBMClassifier.
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## Output
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The script outputs the results of each model to a text file in the specified output directory. The results include accuracy, precision, recall, F1 score, and area under the ROC curve.
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## Authors
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Gabriel Sousa - gabrieltxs
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## License
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This project is licensed under the MIT License - see the LICENSE.md file for details.
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[![MIT License](https://img.shields.io/badge/License-MIT-green.svg)](https://choosealicense.com/licenses/mit/)
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