Title: EMFlow: Data Imputation in Latent Space via EM and Deep Flow Models. Abstract: The presence of missing values within high-dimensional data is an ubiquitous problem for many applied sciences. A serious limitation of many available data mining and machine learning methods is their inability to handle partially missing values and so an integrated approach that combines imputation and model estimation is vital for down-stream analysis. A computationally fast algorithm, called EMFlow, is introduced that performs imputation in a latent space via an online version of Expectation-Maximization (EM) algorithm by using a normalizing flow (NF) model which maps the data space to a latent space. The proposed EMFlow algorithm is iterative, involving updating the parameters of online EM and NF alternatively. Extensive experimental results for high-dimensional multivariate and image datasets are presented to illustrate the superior performance of the EMFlow compared to a couple of recently available methods in terms of both predictive accuracy and speed of algorithmic convergence.