where are cftr channels located?
The gene defective in cystic fibrosis, the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene, was identified in 1989 [5], [6], [7]. This gene encodes a small conductance ATP- and cAMP-dependent chloride channel that is found at the apical border of epithelial cells lining most exocrine glands.