TRICYCLIC CARBOXAMIDES FOR CONTROLLING ARTHROPODSThe invention relates, inter alia, to compounds of general formula (I). The invention also relates to methods for synthesizing the compounds of formula (I). The compounds according to the invention are in particular suitable for controlling insects, arachnids and nematodes in agricultural applications and for controlling ectoparasites in veterinary medicine.A compound of formula (I) in whichR1 is H, optionally in each case mutually independently substituted by one or more substituents, selected from amino, hydroxyl, halogen, nitro, cyano, isocyano, mercapto, isothiocyanato, C1-C4-carboxyl, carbonamide, SF5, aminosulfonyl, C1-C4-alkyl, C3-C4-cycloalkyl, C2-C4-alkenyl, C5-C6-cycloalkenyl, C2-C4-alkynyl, N-mono-C1-C4-alkylamino, N,N-di-C1-C4-alkylamino, N—C1-C4-alkanoylamino, C1-C4-alkoxy, C2-C4-alkenyloxy, C2-C4-alkynyloxy, C3-C4-cycloalkoxy, C5-C6-cycloalkenyloxy, C1-C4-alkoxycarbonyl, C2-C4-alkenyloxycarbonyl, C2-C4-alkynyloxycarbonyl, C6-,C10-,C4-aryloxycarbonyl, C1-C4-alkanoyl, C2-C4-alkenylcarbonyl, C2-C4-alkynylcarbonyl, C6-,C10-,C14-arylcarbonyl, C1-C4-alkylsulfanyl, C3-C4-cycloalkylsulfanyl, C1-C4-alkylthio, C2-C4-alkenylthio, C5-C6-cycloalkenylthio, C2-C4-alkynylthio, C1-C4-alkylsulfenyl and C1-C4-alkylsulfinyl, wherein both enantiomers of the C1-C4-alkylsulfinyl group are included, C1-C4-alkylsulfonyl, N-mono-C1-C4-alkylaminosulfonyl, N,N-di-C1-C4-alkylaminosulfonyl, C1-C4-alkylphosphinyl, C1-C4-alkylphosphonyl, wherein for C1-C4-alkylphosphinyl or C1-C4-alkylphosphonyl both enantiomers are included, N—C1-C4-alkylaminocarbonyl, N,N-di-C1-C4-alkylaminocarbonyl, N—C1-C4-alkanoylaminocarbonyl, N—C1-C4-alkanoyl-N—C1-C4-alkylaminocarbonyl, C6-,C10-,C14-aryl, C6-,C10-,C14-aryloxy, benzyl, benzyloxy, benzylthio, C6-,C10-,C14-arylthio, C6-,C10-,C14-arylamino, benzylamino, heterocyclyl and trialkylsilyl, having substituents linked by a double bond such as C1-C4-alkylidene, an oxo group-substituted or an imino group-substituted C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C7-cycloalkyl, C1-C6-alkylcarbonyl, C1-C6-alkoxycarbonyl, C6-,C10-,C14-aryl(C1-C3)-alkyl, 3, 4, 5, 6, 7, 8, 9 or 10-membered heterocyclyl (optionally thietanyl optionally thiethanyl-3-yl, oxidothiethane such as 1-oxidothietan-3-yl, or dioxidothiethane such as 1,1-dioxidothietan-3-yl) or 3, 4, 5, 6, 7, 8, 9 or 10-membered-heterocyclyl(C1-C3)-alkyl, optionally C3-C7-cycloalkyl optionally substituted by halogen or cyano, orC6-,C10-,C14-aryl(C1-C3)-alkyl, wherein C6-,C10-,C14-Aryl may optionally be substituted mutually independently by one or more substituents selected from amino, hydroxyl, halogen, nitro, cyano, isocyano, mercapto and C1-C4-alkyl, orC1-C6-alkylcarbonyl;optionally C3-cycloalkyl optionally substituted by cyano or C6-aryl(C1-C3)-alkyl;R2 is H or optionally mutually independently substituted by one or more substituents selected from amino, hydroxyl, halogen, nitro, cyano, mercapto, C1-C4-carboxyl, carbonamide, aminosulfonyl, C1-C4-alkyl, C3-C4-cycloalkyl, C2-C4-alkenyl, C5-C6-cycloalkenyl, C2-C4-alkynyl, N-mono-C1-C4-alkylamino, N,N-di-C1-C4-alkylamino, N—C1-C4-alkanoylamino, C1-C4-alkoxy, C2-C4-alkenyloxy, C2-C4-alkynyloxy, C3-C4-cycloalkoxy, C5-C6-cycloalkenyloxy, C1-C4-alkoxycarbonyl, C2-C4-alkenyloxycarbonyl, C2-C4-alkynyloxycarbonyl, C6-,C10-,C14-aryloxycarbonyl, C1-C4-alkanoyl, C2-C4-alkenylcarbonyl, C2-C4-alkynylcarbonyl, C6-,C10-,C14-arylcarbonyl, C1-C4-alkylsulfanyl, C3-C4-cycloalkylsulfanyl, C1-C4-alkylthio, C2-C4-alkenylthio, C5-C6-cycloalkenylthio, C2-C4-alkynylthio, C1-C4-alkylsulfenyl and C1-C4-alkylsulfinyl, wherein both enantiomers of the C1-C4-alkylsulfinyl group are included, C1-C4-alkylsulfonyl, N-mono-C1-C4-alkylaminosulfonyl, N,N-di-C1-C4-alkylaminosulfonyl, C1-C4-alkylphosphinyl, C1-C4-alkylphosphonyl, wherein both enantiomers are included for C1-C4-alkylphosphinyl or C1-C4-alkylphosphonyl, N—C1-C4-alkylaminocarbonyl, N,N-di-C1-C4-alkylaminocarbonyl, N—C1-C4-alkanoylaminocarbonyl, N—C1-C4-alkanoyl-N—C1-C4-alkylaminocarbonyl, C6-,C10-,C14-aryl, C6-,C10-,C4-aryloxy, benzyloxy, benzylthio, C6-,C10-,C14-arylthio, C6-,C10-,C14-arylamino, benzylamino, heterocyclyl and trialkylsilyl, having substituents linked by a double bond such as C1-C4-alkylidene or an oxo group-substituted C1-C6-alkyl;the moietiesA1, A2 and A3 are each independently N, O, CR3, S or N—R4, optionally N, CR3, S or N—R4, wherein A1, A2, A3, Z and the carbon atom of the ring form an aromatic system;R3 is each independently H, Cl, F, I, Br or optionally halogenated C1-C4-alkyl, optionally methyl;R4 is each independently H or optionally halogenated C1-C4-alkyl, optionally methyl;Q is O or S, optionally O;Z is C or N; optionally C;B1 and B5 are each independently N or C—R5 andB2, B3 and B4 are each independently C—R5, whereinR5 is each independently H, halogen, cyano, nitro, SF5, in each case optionally substituted by one or more substituents selected from amino, hydroxyl, halogen, nitro, cyano, isocyano, mercapto, isothiocyanato, C1-C4-carboxyl, carbonamide, SF5, aminosulfonyl, C1-C4-alkyl, C3-C4-cycloalkyl, C2-C4-alkenyl, C5-C6-cycloalkenyl, C2-C4-alkynyl, N-mono-C1-C4-alkylamino, N,N-di-C1-C4-alkylamino, N—C1-C4-alkanoylamino, C1-C4-alkoxy, C2-C4-alkenyloxy, C2-C4-alkynyloxy, C3-C4-cycloalkoxy, C5-C6-cycloalkenyloxy, C1-C4-alkoxycarbonyl, C2-C4-alkenyloxycarbonyl, C2-C4-alkynyloxycarbonyl, C...
절지동물을 방제하기 위한 트리시클릭 카르복스아미드본 발명은, 특히, 화학식 (I)의 화합물에 관한 것이다. 본 발명은 또한 화학식 (I)의 화합물을 합성하는 방법에 관한 것이다. 본 발명에 따른 화합물은 농업 응용분야에서 곤충류, 거미류 및 선충류를 방제하고, 수의학 의약분야에서 외부기생충을 방제하는데 특히 적합하다.화학식 (I)의 화합물 및 화학식 (I)의 화합물의 염, N-옥시드 및 호변이성질체 형태.여기서R1은 H이고, 이는 임의로 각 경우에 아미노, 히드록실, 할로겐, 니트로, 시아노, 이소시아노, 메르캅토, 이소티오시아네이토, C1-C4-카르복실, 카본아미드, SF5, 아미노술포닐, C1-C4-알킬, C3-C4-시클로알킬, C2-C4-알케닐, C5-C6-시클로알케닐, C2-C4-알키닐, N-모노-C1-C4-알킬아미노, N,N-디-C1-C4-알킬아미노, N-C1-C4-알카노일아미노, C1-C4-알콕시, C2-C4-알케닐옥시, C2-C4-알키닐옥시, C3-C4-시클로알콕시, C5-C6-시클로알케닐옥시, C1-C4-알콕시카르보닐, C2-C4-알케닐옥시카르보닐, C2-C4-알키닐옥시카르보닐, C6-,C10-,C14-아릴옥시카르보닐, C1-C4-알카노일, C2-C4-알케닐카르보닐, C2-C4-알키닐카르보닐, C6-,C10-,C14-아릴카르보닐, C1-C4-알킬술파닐, C3-C4-시클로알킬술파닐, C1-C4-알킬티오, C2-C4-알케닐티오, C5-C6-시클로알케닐티오, C2-C4-알키닐티오, C1-C4-알킬술페닐 및 C1-C4-알킬술피닐 (여기서 C1-C4-알킬술피닐 기의 둘 다의 거울상이성질체가 포함됨), C1-C4-알킬술포닐, N-모노-C1-C4-알킬아미노술포닐, N,N-디-C1-C4-알킬아미노술포닐, C1-C4-알킬포스피닐, C1-C4-알킬포스포닐 (여기서 C1-C4-알킬포스피닐 또는 C1-C4-알킬포스포닐의 경우 둘 다의 거울상이성질체가 포함됨), N-C1-C4-알킬아미노카르보닐, N,N-디-C1-C4-알킬아미노카르보닐, N-C1-C4-알카노일아미노카르보닐, N-C1-C4-알카노일-N-C1-C4-알킬아미노카르보닐, C6-,C10-,C14-아릴, C6-,C10-,C14-아릴옥시, 벤질, 벤질옥시, 벤질티오, C6-,C10-,C14-아릴티오, C6-,C10-,C14-아릴아미노, 벤질아미노, 헤테로시클릴 및 트리알킬실릴 (이중 결합에 의해 연결된 치환기, 예컨대 C1-C4-알킬리덴을 가짐), 옥소 기-치환된 또는 이미노 기-치환된 C1-C6-알킬, C2-C6-알케닐, C2-C6-알키닐, C3-C7-시클로알킬, C1-C6-알킬카르보닐, C1-C6-알콕시카르보닐, C6-,C10-,C14-아릴(C1-C3)-알킬, 3, 4, 5, 6, 7, 8, 9 또는 10-원 헤테로시클릴 (예를 들어, 티에타닐 예컨대 티에타닐-3-일, 옥시도티에탄 예컨대 1-옥시도티에탄-3-일, 또는 디옥시도티에탄 예컨대 1,1-디옥시도티에탄-3-일) 또는 3, 4, 5, 6, 7, 8, 9 또는 10-원-헤테로시클릴(C1-C3)-알킬로부터 선택된 1개 이상의 치환기에 의해 서로 독립적으로 치환되고,바람직하게는 할로겐 또는 시아노에 의해 임의로 치환된 C3-C7-시클로알킬, 또는C6-,C10-,C14-아릴(C1-C3)-알킬 (여기서 C6-,C10-,C14-아릴은 아미노, 히드록실, 할로겐, 니트로, 시아노, 이소시아노, 메르캅토 및 C1-C4-알킬로부터 선택된 1개 이상의 치환기에 의해 서로 독립적으로 임의로 치환될 수 있음), 또는C1-C6-알킬카르보닐이고;보다 바람직하게는 시아노에 의해 임의로 치환된 C3-시클로알킬 또는 C6-아릴(C1-C3)-알킬이고;R2는 H이거나, 또는 임의로 아미노, 히드록실, 할로겐, 니트로, 시아노, 메르캅토, C1-C4-카르복실, 카본아미드, 아미노술포닐, C1-C4-알킬, C3-C4-시클로알킬, C2-C4-알케닐, C5-C6-시클로알케닐, C2-C4-알키닐, N-모노-C1-C4-알킬아미노, N,N-디-C1-C4-알킬아미노, N-C1-C4-알카노일아미노, C1-C4-알콕시, C2-C4-알케닐옥시, C2-C4-알키닐옥시, C3-C4-시클로알콕시, C5-C6-시클로알케닐옥시, C1-C4-알콕시카르보닐, C2-C4-알케닐옥시카르보닐, C2-C4-알키닐옥시카르보닐, C6-,C10-,C14-아릴옥시카르보닐, C1-C4-알카노일, C2-C4-알케닐카르보닐, C2-C4-알키닐카르보닐, C6-,C10-,C14-아릴카르보닐, C1-C4-알킬술파닐, C3-C4-시클로알킬술파닐, C1-C4-알킬티오, C2-C4-알케닐티오, C5-C6-시클로알케닐티오, C2-C4-알키닐티오, C1-C4-알킬술페닐 및 C1-C4-알킬술피닐 (여기서 C1-C4-알킬술피닐 기의 둘 다의 거울상이성질체가 포함됨), C1-C4-알킬술포닐, N-모노-C1-C4-알킬아미노술포닐, N,N-디-C1-C4-알킬아미노술포닐, C1-C4-알킬포스피닐, C1-C4-알킬포스포닐 (여기서 C1-C4-알킬포스피닐 또는 C1-C4-알킬포스포닐의 경우 둘 다의 거울상이성질체가 포함됨), N-C1-C4-알킬아미노카르보닐, N,N-디-C1-C4-알킬아미노카르보닐, N-C1-C4-알카노일아미노카르보닐, N-C1-C4-알카노일-N-C1-C4-알킬아미노카르보닐, C6-,C10-,C14-아릴, C6-,C10-,C14-아릴옥시, 벤질옥시, 벤질티오, C6-,C10-,C14-아릴티오, C6-,C10-,C14-아릴아미노, 벤질아미노, 헤테로시클릴 및 트리알킬실릴 (이중 결합에 의해 연결된 치환기, 예컨대 C1-C4-알킬리덴을 가짐) 또는 옥소 기-치환된 C1-C6-알킬로부터 선택된 1개 이상의 치환기에 의해 서로 독립적으로 치환되고;모이어티A1, A2 및 A3은 각각 독립적으로 N, O, CR3, S 또는 N-R4, 바람직하게는 N, CR3, S 또는 N-R4이고, 여기서 고리의 A1, A2, A3, Z 및 탄소 원자는 방향족계를 형성하고;R3은 각각 독립적으로 H, Cl, F, I, Br 또는 임의로 할로겐화된 C1-C4-알킬, 바람직하게는 메틸이고;R4는 각각 독립적으로 H 또는 임의로 할로겐화된 C1-C4-알킬, 바람직하게는 메틸이고;Q는 O 또는 S, 바람직하게는 O이고;Z는 C 또는 N; 바람직하게는 C이고;B1 및 B5는 각각 독립적으로 N 또는 C-R5이고B2, B3 및 B4는 각각 독립적으로 C-R5이고, 여기서R5는 각각 독립적으로 H, 할로겐, 시아노, 니트로, SF5이고, 이는 각 경우에 임의로 아미노, 히드록실, 할로겐, 니트로, 시아노, 이소시아노, 메르캅토, 이소티오시아네이토, C1-C4-카르복실, 카본아미드, SF5, 아미노술포닐, C1-C4-알킬, C3-C4-시클로알킬, C2-C4-알케닐, C5-C6-시클로알케닐, C2-C4-알키닐, N-모노-C1-C4-알킬아미노, N,N-디-C1-C4-알킬아미노, N-C1-C4-알카노일아미노, C1-C4-알콕시, C2-C4-알케닐옥시, C2-C4-알키닐옥시, C3-C4-시클로알콕시, C5-C6-시클로알케닐옥시, C1-C4-알콕시카르보닐, C2-C4-알케닐옥시카르보닐, C2-C4-알키닐옥시카르보닐, C6-,C10-,C14-아릴옥시카르보닐, C1-C4-알카노일, C2-C4-알케닐카르보닐, C2-C4-알키닐카르보닐, C6-,C10-,C14-아릴카르보닐, C1-C4-알킬술파닐, C3-C4-시클로알킬술파닐, C1-C4-알킬티오, C2-C4-알케닐티오, C5-C6-시클로알케닐티오, C2-C4-알키닐티오, C1-C4-알킬술페닐 및 C1-C4-알킬술피닐 (여기서 C1-C4-알킬술피닐 기의 둘 다의 거울상이성질체가 포함됨), C1-C4-알킬술포닐, N-모노-C1-C4-알킬아미노술포닐, N,N-디-C1-C4-알킬아미노술포닐, C1-C4-알킬포스피닐, C1-C4-알킬포스포닐 (여기서 C1-C4-알킬포스피닐 또는 C1-C4-알킬포스포닐의 경우 둘 다의 거울상이성질체가 포함됨), N-C1-C4-알킬아미노카르보닐, N,N-디-C1-C4-알킬아미노카르보닐, N-C1-C4-알카노일아미노카르보닐, N-C1-C4-알카노일-N-C1-C4-알킬아미노카르보닐, C6-,C10-,C14-아릴, C6-,C10-,C14-아릴옥시, 벤질, 벤질옥시, 벤질티오, C6-,C10-,C14-아릴티오, C6-,C10-,C14-아릴아미노, 벤질아미노, 헤테로시클릴 및 트리알킬실릴 (이중 결합에 의해 연결된 치환기, 예컨대 C1-C4-알킬리덴을 가짐), 옥소 기-치환된 또는 이미노 기-치환된 C1-C6-알킬, C3-C6-시클로알킬, C1-C6-알콕시, N-C1-C6-알콕시이미노-C1-C3-알킬, C1-C6-알킬술파닐, C1-C6-알킬술피닐, C1-C6-알킬술포닐, N-C1-C6-알킬아미노 또는 N,N-디-C1-C6-알킬아미노로부터 선택된 1개 이상의 치환기에 의해 치환되고;T는 하기 열거된 5-원 헤테로방향족 T1-T4 및 T6 중 하나이고,여기서 에 대한 결합은 해쉬 #로 표시된다.