PROCESS FOR PREPARING SUBSTITUTED IMIDAZOLE DERIVATIVESThe invention relates to a process for preparing substituted imidazol derivatives of formula (II) starting from compounds of formula (I) via an intermediate stage of formula (IVa) or (IVb), wherein the structural elements indicated in formulae (I), (II), (VIa) and (IVb) have the meanings indicated in the description. The invention further relates to the intermediate stages of formulae (IVa) and (IVb).Process for preparing compounds of formula (ii)whereinq represents a structural elementwherein the symbol # represents a bond to the rest of the molecule, andq1represents n or cr6，q2represents n or cr6，q3represents a group of n or c, wherein,q4representation o, s, n, cr6or nr7，q5represents a group of n or c, wherein,q6represents n or ch, andq7represents a group of n or ch,wherein the variable q1、q2、q3、q4、q5、q6and q7up to five of which represent nitrogen simultaneously, and q3and q5not simultaneously represent n, andr6represents hydrogen, (c)1-c4) alkyl radicals, (c)1-c4) -haloalkyl, (c)1-c4) cyanoalkyl, (c)1-c4) -alkoxy- (c)1-c4) alkyl radicals, (c)1-c4) -haloalkoxy- (c)1-c4) alkyl radicals, (c)2-c4) -alkenyl, (c)2-c4) -alkenyloxy- (c)1-c4) alkyl radicals, (c)2-c4) -haloalkenyloxy- (c)1-c4) alkyl radicals, (c)2-c4) -haloalkenyl, (c)2-c4) -cyanoalkenyl, (c)2-c4) -alkynyl, (c)2-c4) -alkynyloxy- (c)1-c4) alkyl radicals, (c)2-c4) -haloalkynyl, (c)3-c6) -cycloalkyl, (c)3-c6) -cycloalkyl- (c)3-c6) -cycloalkyl, (c)1-c4) -alkyl- (c)3-c6) -cycloalkanesbase, halo- (c)3-c6) -cycloalkyl, (c)1-c4) -alkylthio- (c)1-c4) alkyl radicals, (c)1-c4) -alkylsulfinyl- (c)1-c4) alkyl radicals, (c)1-c4) -alkylsulfonyl- (c)1-c4) -alkyl or (c)1-c4) -alkylcarbonyl- (c)1-c4) -alkyl, andr7is represented by (c)1-c4) alkyl radicals, (c)1-c4) -haloalkyl, (c)1-c4) cyanoalkyl, (c)1-c4) -alkoxy- (c)1-c4) alkyl radicals, (c)1-c4) -haloalkoxy- (c)1-c4) alkyl radicals, (c)2-c4) -alkenyl, (c)2-c4) -alkenyloxy- (c)1-c4) alkyl radicals, (c)2-c4) -haloalkenyloxy- (c)1-c4) alkyl radicals, (c)2-c4) -haloalkenyl, (c)2-c4) -cyanoalkenyl, (c)2-c4) -alkynyl, (c)2-c4) -alkynyloxy- (c)1-c4) alkyl radicals, (c)2-c4) -haloalkynyl, (c)3-c6) -cycloalkyl, (c)3-c6) -cycloalkyl- (c)3-c6) -cycloalkyl, (c)1-c4) -alkyl- (c)3-c6) -cycloalkyl, halo- (c)3-c6) -cycloalkyl, (c)1-c4) -alkylthio- (c)1-c4) alkyl radicals, (c)1-c4) -alkylsulfinyl- (c)1-c4) alkyl radicals, (c)1-c4) -alkylsulfonyl- (c)1-c4) -alkyl or (c)1-c4) -alkylcarbonyl- (c)1-c4) -an alkyl group,a represents hydrogen, cyano, halogen, or (c)1-c4) alkyl radicals, (c)1-c4) -haloalkyl, (c)2-c4) -alkenyl, (c)2-c4) -haloalkenyl, (c)2-c4) -alkynyl radical、(c2-c4) -haloalkynyl, (c)3-c6) -cycloalkyl, (c)3-c6) -cycloalkyl- (c)3-c6) -cycloalkyl, (c)1-c4) -alkyl- (c)3-c6) -cycloalkyl, (c)1-c4) -alkoxy, (c)1-c4) -haloalkoxy, (c)1-c4) -alkoxyimino group, (c)1-c4) alkylthio group(s), (c)1-c4) -haloalkylthio, (c)1-c4) -alkylsulfinyl, (c)1-c4) -haloalkylsulfinyl, (c)1-c4) -alkylsulfonyl, (c)1-c4) -haloalkylsulfonyl, (c)1-c4) -alkylsulfonyloxy, (c)1-c4) -alkylcarbonyl, (c)1-c4) -haloalkylcarbonyl, aminocarbonyl, (c)1-c4) -alkylaminocarbonyl, di- (c)1-c4) -alkylaminocarbonyl, (c)1-c4) -alkylsulfonylamino, (c)1-c4) alkylamino, di- (c)1-c4) alkylamino, aminosulfonyl, (c)1-c4) an alkylaminosulfonyl or di- (c)1-c4) -alkylaminosulfonyl, ora represents-o-cf2-o-and with q1and the carbon atoms to which they are attached together form a 5-membered ring, wherein q1which represents carbon, is a carbon atom,w represents halogen or s (o)nr8whereinr8is represented by (c)1-c6) alkyl radicals, (c)1-c6) cyanoalkyl, (c)1-c6) -alkoxy- (c)1-c6) alkyl radicals, (c)1-c6) -haloalkyl, (c)2-c6) -alkenyl, (c)2-c6) -haloalkenyl, (c)2-c6) -alkynyl, (c)2-c6) -haloalkynyl or (c)3-c8) -a cycloalkyl group, andn represents 0, 1 or 2,v represents (c)1-c6) alkyl radicals, (c)1-c6) -haloalkyl, (c)1-c6) cyanoalkyl, (c)1-c6) -alkoxy- (c)1-c6) alkyl radicals, (c)1-c6) -haloalkoxy- (c)1-c6) alkyl radicals, (c)2-c6) -alkenyl, (c)2-c6) -alkenyloxy- (c)1-c6) alkyl radicals, (c)2-c6) -haloalkenyloxy- (c)1-c6) alkyl radicals, (c)2-c6) -haloalkenyl, (c)2-c6) -cyanoalkenyl, (c)2-c6) -alkynyl, (c)2-c6) -alkynyloxy- (c)1-c6) alkyl radicals, (c)2-c6) -haloalkynyloxy- (c)1-c6) alkyl radicals, (c)2-c6) -haloalkynyl, (c)2-c6) -cyanoalkynyl, (c)3-c8) -cycloalkyl, (c)3-c8) -cycloalkyl- (c)3-c8) -cycloalkyl, (c)1-c6) -alkyl- (c)3-c8) -cycloalkyl, halo- (c)3-c8) -cycloalkyl, cyano- (c)3-c8) -cycloalkyl, (c)1-c6) -alkylthio- (c)1-c6) alkyl radicals, (c)1-c6) -haloalkylthio- (c)1-c6) alkyl radicals, (c)1-c6) -alkylsulfinyl- (c)1-c6) alkyl radicals, (c)1-c6) -haloalkylsulfinyl- (c)1-c6) alkyl radicals, (c)1-c6) -alkylsulfonyl- (c)1-c6) alkyl radicals, (c)1-c6) -haloalkylsulfonyl- (c)1-c6) alkyl radicals, (c)1-c6) -alkylcarbonyl- (c)1-c6) alkyl radicals, (c)1-c6) -haloalkylcarbonyl- (c)1-c6) alkyl radicals, (c)1-c6) -alkoxycarbonyl- (c)1-c6) -alkyl or (c)1-c6) -haloalkoxycarbonyl- (c)1-c6) -alkyl, andy represents halogen, cyano, nitro, (c)1-c4) alkyl radicals, (c)1-c4) -haloalkyl, (c)1-c4) -alkoxy, (c)1-c4) -haloalkoxy, (c)1-c4) alkylthio group(s), (c)1-c4) -haloalkylthio, (c)1-c4) -alkylsulfinyl, (c)1-c4) -haloalkylsulfinyl, (c)1-c4) -alkylsulfonyl, (c)1-c4) haloalkylsulfonyl, scn, (c)1-c4) -alkylcarbonyl, (c)1-c4) -haloalkylcarbonyl, (c)1-c4) alkoxycarbonyl, (c)1-c4) -haloalkoxycarbonyl, aminocarbonyl, (c)1-c4) -alkylaminocarbonyl, di- (c)1-c4) -alkylaminocarbonyl, (c)1-c4) -haloa...
치환된 이미다졸 유도체의 제조 방법본 발명은 하기 화학식 (I)의 화합물로부터 출발하여 하기 화학식 (IVa) 또는 (IVb)의 중간체 단계를 거쳐 하기 화학식 (II)의 치환된 이미다졸 유도체를 제조하는 방법에 관한 것이다:[이미지][이미지][이미지] 여기서 화학식 (I), (II), (IVa) 및 (IVb)에 제시된 구조적 요소는 발명의 설명에 제시된 의미를 갖는다. 본 발명은 또한 화학식 (IVa) 및 (IVb)의 중간체 단계에 관한 것이다.화학식 (II)의 화합물을 제조하는 방법이며,[이미지]여기서Q는 하기 구조적 요소를 나타내고:[이미지]여기서 기호 #은 분자의 나머지 부분에 대한 결합을 나타내고,Q1은 N 또는 CR6을 나타내고,Q2는 N 또는 CR6을 나타내고,Q3은 N 또는 C를 나타내고,Q4는 O, S, N, CR6 또는 NR7을 나타내고,Q5는 N 또는 C를 나타내고,Q6은 N 또는 CH를 나타내고,Q7은 N 또는 CH를 나타내고,여기서 가변기 Q1, Q2, Q3, Q4, Q5, Q6 및 Q7 중 최대 5개는 동시에 질소를 나타내고, Q3 및 Q5는 동시에 N을 나타내지는 않고,R6은 수소, (C1-C4)-알킬, (C1-C4)-할로알킬, (C1-C4)-시아노알킬, (C1-C4)-알콕시-(C1-C4)-알킬, (C1-C4)-할로알콕시-(C1-C4)-알킬, (C2-C4)-알케닐, (C2-C4)-알케닐옥시-(C1-C4)-알킬, (C2-C4)-할로알케닐옥시-(C1-C4)-알킬, (C2-C4)-할로알케닐, (C2-C4)-시아노알케닐, (C2-C4)-알키닐, (C2-C4)-알키닐옥시-(C1-C4)-알킬, (C2-C4)-할로알키닐, (C3-C6)-시클로알킬, (C3-C6)-시클로알킬-(C3-C6)-시클로알킬, (C1-C4)-알킬-(C3-C6)-시클로알킬, 할로-(C3-C6)-시클로알킬, (C1-C4)-알킬티오-(C1-C4)-알킬, (C1-C4)-알킬술피닐-(C1-C4)-알킬, (C1-C4)-알킬술포닐-(C1-C4)-알킬 또는 (C1-C4)-알킬카르보닐-(C1-C4)-알킬을 나타내고,R7은 (C1-C4)-알킬, (C1-C4)-할로알킬, (C1-C4)-시아노알킬, (C1-C4)-알콕시-(C1-C4)-알킬, (C1-C4)-할로알콕시-(C1-C4)-알킬, (C2-C4)-알케닐, (C2-C4)-알케닐옥시-(C1-C4)-알킬, (C2-C4)-할로알케닐옥시-(C1-C4)-알킬, (C2-C4)-할로알케닐, (C2-C4)-시아노알케닐, (C2-C4)-알키닐, (C2-C4)-알키닐옥시-(C1-C4)-알킬, (C2-C4)-할로알키닐, (C3-C6)-시클로알킬, (C3-C6)-시클로알킬-(C3-C6)-시클로알킬, (C1-C4)-알킬-(C3-C6)-시클로알킬, 할로-(C3-C6)-시클로알킬, (C1-C4)-알킬티오-(C1-C4)-알킬, (C1-C4)-알킬술피닐-(C1-C4)-알킬, (C1-C4)-알킬술포닐-(C1-C4)-알킬 또는 (C1-C4)-알킬카르보닐-(C1-C4)-알킬을 나타내고,A는 수소, 시아노, 할로겐, (C1-C4)-알킬, (C1-C4)-할로알킬, (C2-C4)-알케닐, (C2-C4)-할로알케닐, (C2-C4)-알키닐, (C2-C4)-할로알키닐, (C3-C6)-시클로알킬, (C3-C6)-시클로알킬-(C3-C6)-시클로알킬, (C1-C4)-알킬-(C3-C6)-시클로알킬, (C1-C4)-알콕시, (C1-C4)-할로알콕시, (C1-C4)-알콕시이미노, (C1-C4)-알킬티오, (C1-C4)-할로알킬티오, (C1-C4)-알킬술피닐, (C1-C4)-할로알킬술피닐, (C1-C4)-알킬술포닐, (C1-C4)-할로알킬술포닐, (C1-C4)-알킬술포닐옥시, (C1-C4)-알킬카르보닐, (C1-C4)-할로알킬카르보닐, 아미노카르보닐, (C1-C4)-알킬아미노카르보닐, 디-(C1-C4)-알킬아미노카르보닐, (C1-C4)-알킬술포닐아미노, (C1-C4)-알킬아미노, 디-(C1-C4)-알킬아미노, 아미노술포닐, (C1-C4)-알킬아미노술포닐 또는 디-(C1-C4)-알킬아미노술포닐을 나타내거나, 또는A는 -O-CF2-O-를 나타내고, Q1 및 그가 부착되어 있는 탄소 원자와 함께 5-원 고리를 형성하고, 여기서 Q1은 탄소를 나타내고,W는 할로겐 또는 S(O)nR8을 나타내고, 여기서R8은 (C1-C6)-알킬, (C1-C6)-시아노알킬, (C1-C6)-알콕시-(C1-C6)-알킬, (C1-C6)-할로알킬, (C2-C6)-알케닐, (C2-C6)-할로알케닐, (C2-C6)-알키닐, (C2-C6)-할로알키닐 또는 (C3-C8)-시클로알킬을 나타내고,n은 0, 1 또는 2를 나타내고,V는 (C1-C6)-알킬, (C1-C6)-할로알킬, (C1-C6)-시아노알킬, (C1-C6)-알콕시-(C1-C6)-알킬, (C1-C6)-할로알콕시-(C1-C6)-알킬, (C2-C6)-알케닐, (C2-C6)-알케닐옥시-(C1-C6)-알킬, (C2-C6)-할로알케닐옥시-(C1-C6)-알킬, (C2-C6)-할로알케닐, (C2-C6)-시아노알케닐, (C2-C6)-알키닐, (C2-C6)-알키닐옥시-(C1-C6)-알킬, (C2-C6)-할로알키닐옥시-(C1-C6)-알킬, (C2-C6)-할로알키닐, (C2-C6)-시아노알키닐, (C3-C8)-시클로알킬, (C3-C8)-시클로알킬-(C3-C8)-시클로알킬, (C1-C6)-알킬-(C3-C8)-시클로알킬, 할로-(C3-C8)-시클로알킬, 시아노-(C3-C8)-시클로알킬, (C1-C6)-알킬티오-(C1-C6)-알킬, (C1-C6)-할로알킬티오-(C1-C6)-알킬, (C1-C6)-알킬술피닐-(C1-C6)-알킬, (C1-C6)-할로알킬술피닐-(C1-C6)-알킬, (C1-C6)-알킬술포닐-(C1-C6)-알킬, (C1-C6)-할로알킬술포닐-(C1-C6)-알킬, (C1-C6)-알킬카르보닐-(C1-C6)-알킬, (C1-C6)-할로알킬카르보닐-(C1-C6)-알킬, (C1-C6)-알콕시카르보닐-(C1-C6)-알킬 또는 (C1-C6)-할로알콕시카르보닐-(C1-C6)-알킬을 나타내고,Y는 할로겐, 시아노, 니트로, (C1-C4)-알킬, (C1-C4)-할로알킬, (C1-C4)-알콕시, (C1-C4)-할로알콕시, (C1-C4)-알킬티오, (C1-C4)-할로알킬티오, (C1-C4)-알킬술피닐, (C1-C4)-할로알킬술피닐, (C1-C4)-알킬술포닐, (C1-C4)-할로알킬술포닐, SCN, (C1-C4)-알킬카르보닐, (C1-C4)-할로알킬카르보닐, (C1-C4)-알콕시카르보닐, (C1-C4)-할로알콕시카르보닐, 아미노카르보닐, (C1-C4)-알킬아미노카르보닐, 디-(C1-C4)-알킬아미노카르보닐, (C1-C4)-할로알킬아미노카르보닐, (C3-C6)-시클로알킬아미노카르보닐, 아미노티오카르보닐, (C1-C4)-알킬아미노티오카르보닐, 디-(C1-C4)-알킬아미노티오카르보닐, (C1-C4)-할로알킬아미노티오카르보닐, (C3-C6)-시클로알킬아미노티오카르보닐, 아미노, (C1-C4)-알킬아미노, (C1-C4)-할로알킬아미노, 디-(C1-C4)-알킬아미노, (C3-C6)-시클로알킬아미노, (C1-C4)-알킬술포닐아미노, (C1-C4)-알킬카르보닐아미노, (C1-C4)-할로알킬카르보닐아미노, (C1-C4)-알킬카르보닐-(C1-C4)-알킬아미노, (C1-C4)-할로알킬카르보닐-(C1-C4)-알킬아미노, (C3-C6)-시클로알킬카르보닐아미노, (C3-C6)-시클로알킬카르보닐-(C1-C4)-알킬아미노, (C1-C4)-알킬티오카르보닐아미노, (C1-C4)-할로알킬티오카르보닐아미노, (C1-C4)-알킬티오카르보닐-(C1-C4)-알킬아미노, (C1-C4)-할로알킬티오카르보닐-(C1-C4)-알킬아미노, (C3-C6)-시클로알킬티오카르보닐아미노, (C3-C6)-시클로알킬티오카르보닐-(C1-C4)-알킬아미노, (C2-C4)-알케닐, (C2-C4)-할로알케닐, (C2-C4)-시아노알케닐, (C3-C6)-시클로알킬-(C2)-알케닐, (C2-C4)-알키닐 또는 (C2-C4)-할로알키닐을 나타내거나,또는 (C3-C6)-시클로알킬 또는 (C5-C6)-시클로알케닐을 나타내고, 이들 각각은 동일하거나 상이한 치환기에 의해 임의로 일치환 또는 다치환되고, 가능한 치환기는 각 경우에: (C3-C6)-시클로알킬, (C1-C4)-알킬, (C1-C4)-할로알킬, (C1-C4)-알콕시, (C1-C4)-할로알콕시, 아미노카르보닐, 아미노티오카르보닐, 할로겐 또는 시아노이거나,또는 아릴 또는 헤타릴을 나타내고, 이들 각각은 동일하거나 상이한 치환기에 의해 임의로 일치환 또는 다치환되고, 여기서 (헤타릴의 경우) 임의로 적어도 1개의 카르보닐 기가 존재할 수 있고, 가능한 치환기는 각 경우에: 시아노, 카르복실, 할로겐, 니트로, 아세틸, 히드록시, 아미노, SCN, SF5, 트리-(C1-C4)-알킬실릴, (C3-C6)-시클로알킬, (C3-C6)-시클로알킬-(C3-C6)-시클로알킬, (C1-C4)-알킬-(C3-C6)-시클로알킬, (C1-C4)-할로알킬-(C3-C6)-시클로알킬, 할로-(C3-C6)-시클로알킬, 시아노-(C3-C6)-시클로알킬, (C1-C4)-알킬, (C1-C4)-할로알킬, (C1-C4)-시아노알킬, (C1-C4)-히드록시알킬, 히드록시카르보닐-(C1-C4)-알콕시, (C1-C4)-알콕시카르보닐-(C1-C4)-알킬, (C1-C4)-알콕시-(C1-C4)-알킬, (C2-C4)-알케닐, (C2-C4)-할로알케닐, (C2-C4)-시아노알케닐, (C3-C6)-시클로알킬-(C2)-알케닐, (C2-C4)-알키닐, (C2-C4)-할로알키닐, (C2-C4)-시아노알키닐, (C1-C4)-알콕시, (C1-C4)-할로알콕시, (C1-C4)-시아노알콕시, (C1-C4)-알콕시카르보닐-(C1-C4)-알콕시, (C1-C4)-알콕시-(C1-C4)-알콕시, (C1-C4)-알콕시이미노, (C1-C4)-할로알콕시이미노, (C1-C4)-알킬티오, (C1-C4)-할로알킬티오, (C1-C4)-알콕시-(C1-C4)-알킬티오, (C1-C4)-알킬티오-(C1-C4)-알킬, (C1-C4)-알킬술피닐, (C1-C4)-할로알킬술피닐, (C1-C4)-알콕시-(C1-C4)-알킬술피닐, (C1-C4)-알킬술피닐-(C1-C4)-알킬, (C1-C4)-알킬술포닐, (C1-C4)-할로알킬술포닐, (C1-C4)-알콕시-(C1-C4)-알킬술포닐, (C1-C4)-알킬술포닐-(C1-C4)-알킬, (C1-C4)-알킬술포닐옥시, (C1-C4)-할로알킬술포닐옥시, (C1-C4)-알킬카르보닐, (C1-C4)-할로알킬카르보닐, (C1-C4)-알킬카르보닐옥시, (C1-C4)-알콕시카르보닐, (C1-C4)-할로알콕시카르보닐, 아미노카르보닐, (C1-C4)-알킬아미노카르보닐, (C1-C4)-할로알킬아미노카르보닐, 디-(C1-C4)-알킬아미노카르보닐, (C2-C4)-알케닐아미노카르보닐, 디-(C2-C...