A process for preparing a compound (III) is provided, in which the compound (III) is prepared from a methoxycarbonyl derivative through a methoxyamide derivative. These two reaction steps are continuously carried out and substantially the same as one step. The compound (III) is useful as a synthetic intermediate for preparing a dual tyrosine kinase inhibitor and can be conveniently prepared in high yield according to the present invention.
메톡시카보닐체로부터 메톡시아마이드체를 경유하여 목적물(III)을 제조하는 2공정을 연속하여 반응시켜, 이들을 실질상 1공정으로 행하는 제조방법을 제공한다. 본 발명에 의해, 듀얼 타이로신 키나아제 저해제의 제조 중간체로서 유용한 화합물(III)을 간편하고 고효율로 제조할 수 있다.