It comes 12 years after their first, when Jose Mourinho's 2004-05 side stormed to glory, 12 points clear of nearest rivals Arsenal after having lost just once, to Manchester City, all season.
Didier Drogba spearheaded the attack, Claude Makelele reinvented the anchor man role and Frank Lampard top-scored from midfield as the Blues won their first top-flight title in more than half a century.
Antonio Conte's 2016-17 breed have wrapped up the league with two games to spare, with Diego Costa hitting 20 goals [as of 12 May], Eden Hazard impressing and N'Golo Kante winning player of the year.
But who, from Chelsea's first and most recent Premier League-winning teams, would make your combined XI?
Pick your best XI from Chelsea's Premier League winners in 2004-05 and 2016-17.

Earlier Prime Minister David Cameron attended the main celebration at Cleethorpes in North East Lincolnshire.
It featured an aerobatic display by the Red Arrows, a Battle of Britain Memorial Flight and parachute display by the Royal Navy, Army and RAF.
On Monday, a flag-raising ceremony was held at City Hall, in London, to mark this year's events.
Follow live updates of Armed Forces Day events
Alex Baxter, armed forces champion for North East Lincolnshire, said: "Hosting Armed Forces Day will give our residents and others in the region an unparalleled opportunity to show their support and appreciation for serving and former armed forces personnel."
The main celebration also included a display of military vehicles, including the Sandown-class mine countermeasures vessel HMS Blyth, the AS90 artillery tank and the Warrior and Terrier armoured vehicles.
North East Lincolnshire Council leader Ray Oxby said: "Our local Armed Forces Day has previously attracted more than 60,000 people into the area for the weekend to recognise our past and serving military personnel, and I've no doubt that figure will be dwarfed by hosting the national day."

Cornwall Live said its journalists were told they could not broadcast the PM's visit via Facebook Live.
The publication, owned by Trinity Mirror, took to social media to vent its frustrations.
The Conservatives said the reporters' "last minute" request to film had "not been possible" because a pooled resource had already been agreed.
Reporters and broadcasters are traditionally given a pooled resource for video, stills and text at such events.
Read more on this story and others from Cornwall
Cornwall Live sent two reporters and a photographer to cover the prime minister's visit to Helston.
The reporters published a photo of the room they were held in while the PM was interviewed by other media.
Editor Jacqui Merrington said they were "a lot more" than a local newspaper.
"When we arrived... we were told we were not allowed to film anything because we were invited as print media, which seems a bit 20th Century really."
She added: "We are digital media and that is the case for most local media nowadays and to be restricted on that basis seems very archaic."
A spokesman for the Conservatives said Cornwall Live only made a request to film on the morning of the visit.
"One media organisation's last minute request to add a camera to a pre-arranged pool of broadcast cameras was not possible this morning.
"The organisation's journalists did interview the prime minister and their photographer accompanied [her] on a factory tour."
Chelsea's 1-0 win at West Brom on Friday clinched the Blues their fifth Premier League title.
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Tributes were paid to service personnel at hundreds of events around the UK on Armed Forces Day.
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Website reporters covering Theresa May's visit to Cornwall have complained they were not allowed to film her.