Pools, who were relegated from the English Football League last season, lost their opening game at home to Dover on Saturday but started well at Moss Rose, with Cassidy and Jack Munns both firing inches wide.
Macclesfield hit back, with Danny Whitaker's volleyed effort superbly tipped away by goalkeeper Scott Loach.
The home side took the lead in the 38th minute when Elliott Durrell's ball into the box was headed home by Whitaker.
There was a let-off for Hartlepool at the start of the second half when a mistake from defender Scott Harrison set Tyrone Marsh clear but he shot straight at Loach.
Pools levelled after 58 minutes when Cassidy nodded in a cross from Ryan Donaldson and came closest to winning it when the striker's flicked header was saved.
Match report supplied by the Press Association.
Match ends, Macclesfield Town 1, Hartlepool United 1.
Second Half ends, Macclesfield Town 1, Hartlepool United 1.
Substitution, Macclesfield Town. Koby Arthur replaces Elliott Durrell.
Substitution, Macclesfield Town. Scott Wilson replaces Scott Burgess.
Substitution, Hartlepool United. Blair Adams replaces Jack Munns.
Substitution, Macclesfield Town. Kieran Kennedy replaces George Pilkington.
Goal!  Macclesfield Town 1, Hartlepool United 1. Jake Cassidy (Hartlepool United).
Second Half begins Macclesfield Town 1, Hartlepool United 0.
First Half ends, Macclesfield Town 1, Hartlepool United 0.
Jack Munns (Hartlepool United) is shown the yellow card.
Goal!  Macclesfield Town 1, Hartlepool United 0. Danny Whitaker (Macclesfield Town).
Tyrone Marsh (Macclesfield Town) is shown the yellow card.
Liam Donnelly (Hartlepool United) is shown the yellow card.
First Half begins.
Lineups are announced and players are warming up.

Ian Stewart, 56, denies murdering Helen Bailey at their home in Royston, Hertfordshire, in April.
Her body was found in July, dumped in a cesspit under the garage.
St Albans Crown Court heard Mr Stewart told a psychiatric nurse he had thought about taking his own life.
Follow updates on this story and other Hertfordshire news
The nurse Sarah Tooley told the jury she had spoken with Mr Stewart on the phone in May.
He had been to visit Broadstairs in Kent where Ms Bailey had a holiday cottage.
"He'd had thoughts of jumping off a cliff while he was down there," said Ms Tooley.
Earlier, the court was told Mr Stewart had tried to divert a police search of the garage.
According to a statement from Det Con Hollie Daines, read to the court, Mr Stewart said: "If searches are going to take place, you wouldn't find anything in the garage."
When they arrived, DC Daines said Mr Stewart told her he had considered suicide.
She said: "He appeared to be anxious and uncomfortable with what we were asking of him."
On the day of Ms Bailey's disappearance, Mr Stewart claimed he found a note from the Electra Brown author saying she had gone to the holiday cottage in Broadstairs.
According to a statement read to the court, he told police: "If Helen does come back, I don't think I want to be with her any more."
Mr Stewart, of Baldock Road, Royston, Hertfordshire, denies charges of murder, preventing a lawful burial, fraud and three counts of perverting the course of justice.
The trial continues.

Food price inflation was 4.9% in June, compared with 3.2% in May, with rising pork prices partly to blame.
While the headline inflation number was above analysts' expectations, it remains below the government's target figure of 3.5%.
Analysts say the latest figure reduces the prospect of interest rate cuts in 2013.
Cutting interest rates risks inflating a property bubble, while tightening may put additional pressure on the economy in the middle of the current global economic uncertainty.
Bank of America Merrill Lynch economists Lu Ting and Zhi Xiaojia expect authorities to keep monetary policy neutral with "neither easing nor tightening".
China expects economic growth this year to be 7.5% -  which would be the slowest rate in 23 years for the country.
The government is due to release data on gross domestic product for the second quarter of the year on 15 July.
Jake Cassidy's second-half equaliser earned Hartlepool their first point in the Vanarama National League as they drew against Macclesfield.
[NEXT_CONCEPT]
The fiancÃ© of a children's author considered throwing himself off a cliff two months before he was charged with the killing her, a court has heard.
[NEXT_CONCEPT]
China's inflation rate rose by more than expected in June, increasing to 2.7% from 2.1% the month before.