In a documentary aired on BBC Radio 4, the Smack the Pony star claims stories about "brutalised women" have become "entertainment fodder".
Dramas like The Fall, she suggests, are part of an "industry" built on "rape and the ritualistic murder of women".
The show features an interview with a young actress who says she now regrets playing a rape victim on screen.
'Sophie' said her character's rape in the unnamed drama was used as "a shock device" she now feels was gratuitous "titillation".
In an interview for Radio 4's Seriously... podcast, Mackichan said recording the interview had left both her and 'Sophie' "in floods of tears".
The actress also admits that re-watching BBC Two's The Fall in preparation for the programme "had given her nightmares".
The Fall, now in its third series, tells of a serial killer, played by Jamie Dornan, who torments and rapes his victims before murdering them.
Screenwriter Allan Cubitt is heard justifying the violence in Mackichan's documentary, saying he wished to neither "sensationalise" or "sanitise" it.
Mackichan admits The Fall - also starring Gillian Anderson - is "exciting television", but says it is nevertheless "irresponsible" for perpetuating overused stereotypes.
"We do have a lot of what I call crime porn," she continued. "I'd like there to be a real sea change... because it bleeds into our culture.
"The onus is with commissioners who commission these programmes, and with screenwriters... who are pandering to the appetite that has been created."
Alison Graham of the Radio Times is another to have spoken out recently against "graphic portrayals of brutality towards women".
"Using a savage murder of a woman as an attention-grabbing plot device... is too much," she wrote in reference to ITV drama Paranoid.
Body Count Rising can currently be heard on the BBC iPlayer. The next edition of Radio 4's Seriously... podcast is available on Tuesday.
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Trevor O'Neill was shot outside a supermarket in Majorca just after 21:00 local time on Wednesday, Irish national broadcaster RTÃ‰ reports.
His shooting is understood to be linked to a feud between Irish criminal gangs.
Mr O'Neill's partner and three children, aged five, seven and 10, were with him when the attack happened.
They had travelled to Majorca on Saturday for a holiday for his 40th birthday.
Police believe the attack was connected to a dispute between the Hutch and Kinahan groups, but Mr O'Neill was not the intended victim.
The feud between the gangs was sparked by the killing of Dubliner Gary Hutch in Spain last year and most of the resulting violence and murders have happened in Dublin.
Attempts to revive Mr O'Neill at the scene failed and police are said to be searching for up to three suspects.
It is understood that he was not linked to organised crime but may have been talking to a member of the Hutch family at the time.

The incident happened after the vehicle left the A68 in Jedburgh at about 09:40.
Police said a "small number of passengers" on board had been left shaken and were checked over by paramedics at the scene.
Investigations are continuing to determine what caused the bus to leave the road.
It hit a car and also struck a roadside wall a number of times before travelling across a grassy area and finally coming to rest against a metal barrier overhanging the Jed Water.
The route was closed for about an hour while the vehicle was safely removed from the scene.
Actress Doon Mackichan has spoken out about the prevalence of rape and sexual violence in contemporary TV drama.
[NEXT_CONCEPT]
An Irishman who was shot dead on a Spanish island is believed to have been killed in a case of mistaken identity in a gang-related attack.
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A metal barrier has blocked a bus from ending up in a river after a crash in the Scottish Borders.