Reading's Danson, who has scored 89 international goals, suffered a hand injury in February and missed Test series against Australia and Germany.
Great Britain play the Dutch in Amsterdam on Tuesday and Thursday.
"We're looking forward to testing ourselves against the number-one-ranked team," said GB coach Danny Kerry.
East Grinstead's Laura Unsworth and University of Birmingham's Lily Owsley are also fit again after injuries and included in the 20-strong squad.
"It is good to have Laura, Alex and Lily back after long periods of injury and it will be good to have competitive match play to help bring them up to match speed," added Kerry.
England came from 2-0 behind to beat the Dutch on penalties to win the EuroHockey Championships in August, with Danson picking up the player of the tournament award.
Maddie Hinch (GK), Emily Maguire, Shona McCallin, Sam Quek, Nicola White (all Holcombe); Kirsty Mackay (GK), Sophie Bray, Laura Unsworth (East Grinstead); Giselle Ansley, Georgie Twigg, Hollie Webb (Surbiton); Alex Danson, Kate Richardson-Walsh, Helen Richardson-Walsh (Reading); Joie Leigh (Clifton); Hannah Macleod, Ellie Watton (St Albans); Lily Owsley (University of Birmingham); Susannah Townsend (Canterbury); Crista Cullen (unattached).

The actor said he was "thrilled" to be asked to portray Tommy Butler in The Great Train Robbery: A Copper's Tale.
The drama will follow A Robber's Tale, which will view the heist from the perspective of its perpetrators.
Luke Evans will star in that film as Bruce Reynolds, the raid's key planner.
Broadbent said it would be "great fun" to play Butler, "a fascinating copper of the old school", in the drama, to air later this year.
"I have such strong memories of the massive impact of the actual robbery and it is wonderful to find out from the script so much of the real story."
Chris Chibnall, executive producer and writer of the Great Train Robbery dramas, said Broadbent was "a dream piece of casting".
The actor won an Oscar in 2001 for playing the husband of writer Iris Murdoch in Iris and a Bafta in 2007 for playing the campaigner Lord Longford.
Butler, whose astuteness earned him the nickname "Grey Fox", led the investigation into the Great Train Robbery which resulted in several of the robbers receiving lengthy sentences.
He retired in 1969 and died the following year at the age of 57.
Striker Alex Danson has been included in the Great Britain squad for their two Test matches against world and Olympic champions Netherlands.
[NEXT_CONCEPT]
Jim Broadbent will play the detective charged with tracking down the Great Train Robbers in the second of two BBC dramas marking the 50th anniversary of the August 1963 raid.