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30 March 2014 Last updated at 13:54 BST
The remains may be part of a massive emergency burial pit where thousands of plague victims were left 600 years ago.
Lead archaeologist Jay Carver says the find "solves a 660-year-old mystery".
"This discovery is a hugely important step forward in documenting and understanding Europe's most devastating pandemic," he said.

The Zimbabwean hit 10 boundaries in his 207-ball knock before he was lbw to left-arm spinner Jack Leach (3-77).
Leach earlier bowled England batsman James Vince for a third-ball duck as the visitors struggled to 92-4.
Ryan McLaren, though, scored 61 as he and Ervine added 118, while Lewis McManus was 41 not out at the close.
Hampshire are second from bottom of the table but defeated Nottinghamshire in their last outing, while Somerset are fifth, 35 points behind leaders Middlesex.
Lewis Gregory struck the first blow for the home side by bowling Jimmy Adams in the fourth over of play.
Will Smith and Vince followed in successive overs as Somerset wasted no time in bringing their two spinners, Leach and Roelof van der Merwe, into the attack.
Paceman Craig Overton was awarded his county cap during the lunch interval but went through the day wicketless, and it was Leach ended the partnership between Ervine and McLaren by having the latter caught by Tom Abell at short leg.
Hampshire all-rounder Sean Ervine told BBC Radio Solent:
"We looked at the wicket and we all saw it was going to spin.
"They bowled well up front and obviously the partnership with Ryan McLaren was hugely important and great for us.
"He played very well and was a bit unlucky - it was a great catch at short leg.
"We had a game plan, I guess it helped us being left-handed, and just had to bide our time and try and hit the bad balls."

For hosts Forfar Athletic it was a second successive home 3-1 defeat after a run of nine straight wins.
Draper put the Welsh champions ahead after 24 minutes only for Stuart Malcolm to reply after the break against the run of play.
Forfar were on top after the break, but two Draper strikes won the tie.
The Welsh side who started their season in the Champions League qualifiers came to Forfar in confident form with 11 straight wins behind them and they looked the more imposing side in the opening 20 minutes.
Alex Darlington, who had scored both goals in a midweek domestic win, had the first opportunity of the match, but goalkeeper Grant Adam got down smartly to save his 20-yard effort.
TNS wasted another chance as Aeron Edwards came into the box unmarked to meet a corner but sent his header back across goal and off-target.
The Welsh side were dominating possession and the Scottish League Two leaders were struggling to link with Jim Lister and Josh Peters, who were trying to provide an attacking threat.
TNS took the lead after 23 minutes, but it was tinged by controversy.
Forfar were convinced they had won a corner, but a goal-kick was awarded that was swiftly taken and a defensive mis-header found its way to  Draper, who controlled the ball and slipped it beyond Adam.
TNS wasted two further chances to add to their lead before Forfar hit back.
Peters forced a save from Paul Harrison in the TNS goal, but from the resultant corner, Malcolm powered a header in off the bar.
Control switched to Forfar after the break as the home side enjoyed better possession and created the better opportunities.
Jim Lister was twice denied in the same move, with Phil Baker blocking his second effort, while goalkeeper Paul Harrison produced a fingertip save to deny Jamie Bain.
Forfar continued to press and a powerful Martyn Fotheringham free-kick just finished the wrong side of the post.
TNS had shown little in an attacking sense in the second half had the inspiration of substitute Robbie Parry to thank for the goal that put them ahead.
He finished his run into the box by shooting past Adam and Draper netted.
Draper, with one New Zealand cap to his name, secured his hat-trick three minutes from the end when Adam misjudged a long ball and the striker took it past him at the edge of the box to secure victory.
Skeletons unearthed in London Crossrail excavations have been found to be Black Death victims from the great disease of the 14th Century.
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All-rounder Sean Ervine made a vital century for Hampshire as they reached 281-6 on the opening day against Somerset at Taunton.
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Greg Draper grabbed a hat-trick as The New Saints made history by becoming the first non-Scottish side into the Scottish Challenge Cup quarter-finals.