Manimekalai (disambiguation)
Manimekalai is a Tamil epic composed by Sithalai Sattanar. Manimekalai (alternatively spelt Manimegalai) may refer to:
 Manimekhala, a Hindu-Buddhist goddess
 Manimekalai, the titular character of the epic, first appears as the daughter of Kovalan and Madhavi in a preceding Tamil epic Silappatikaram
 Manimekalai (1940 film), a 1940 Indian film adaptation of the epic
 Manimekalai (1959 film), a 1959 Indian film adaptation of the epic
 Manimegalai, an Indian VJ