<unk>  is a clinical state where there is a reduced production or action of thyroid  hormones - Thyroxine (T4) and Triiodothyronine (T3). It is classified based on the location of pathology into primary<unk> , secondary<unk>  and tertiary<unk> . The most common cause worldwide is Iodine deficiency. In iodine sufficient areas the most common cause is autoimmune thyroiditis. Risk factors for the development of<unk>  include female sex, iodine deficiency, selenium deficiency, presence of other autoimmune conditions. Clinical presentation depends on the degree and rapidity of hormone depletion. Patients can be asymptomatic or present with  symptoms like cold intolerance, fatigue, weight gain, constipation, depression, neck mass. The diagnosis of<unk>  is made with the help of biochemical tests measuring TSH and Thyroxine (FT4) levels. Treatment of this condition is with Levothyroxine supplementation.
Hypothyroidism
Hyerthyroidism
Nodular thyroid disease
Acromegaly
Hypopituitarism
Thyroid adenoma
Toxic multinodular goiter
Hyperprolactinemia