<unk>  is a malignant cancer, specifically a sarcoma (cancer of connective tissues), in which the cancer cells are thought to arise from skeletal muscle progenitors.<unk>  is considered as the most common malignant soft tissue tumors and the third most common extracranial solid tumors during childhood. The origin of<unk>  is straited muscle cells. The presentation sites of<unk>  are head and neck, extremities, Genitourinary tract, trunk, orbit, retroperitoneum, bladder, vagina, nasopharynx, and middle ear. The microscopic pathology of<unk>  depends on the histological subtype. Development of<unk>  is the result of specific genetic mutations. The four main subgroups are embryonal<unk>  (ERMS), alveolar<unk>  (ARMS), botryoid and spindle cell (leiomyomatous)<unk> , Sclerosing and spindle cell<unk> . Its two most common forms are embryonal<unk>  and alveolar<unk> . There are no established causes or risk factors for<unk> ; however,<unk>  is more prevalent among the patients with beckwith-wiedemann syndrome, li-fraumeni syndrome, Costello syndrome, and neurofibromatosis. Symptoms of<unk>  can vary greatly depending on the size, location and spread of the tumor. General symptoms of<unk>  are palpable mass, pain, erythmatous skin, fever, nasal discharge, headache, vomiting, change in hearing, vision, speech, or swallowing and physical exam's findings depend on the tumor origin and the presence or absence of metastases. The common sites of metastasis include lungs, bone marrow, and bone. Tissue biopsy is the gold standard test for the diagnosis of<unk> .<unk>  is associated with a 5 year survival rate of 72%. There are two staging classification for<unk>  including Children group (CG) and tumor, node, and metastasis system (TNM). Treatment for<unk>  may consists of chemotherapy, radiation therapy and surgery and treatments depends on staging classification and risk stratification. Primary resection of tumor is one of the main prognostic factors in<unk> .
Rhabdomyosarcoma
Rhabdomyoma
Liposarcoma
Angiosarcoma
Soft tissue sarcoma
Fibrosarcoma
Chondrosarcoma
Lymphangiosarcoma