<unk> s are a diverse type of blood<unk> s characterized by proliferation of a single clone of<unk> <unk> s that produces a homogeneous monoclonal (M) protein. These monoclonal paraprotein are seen in the serum or urine.  Monoclonal<unk> <unk> s are present in the bone marrow or, rarely, in other tissues.<unk> s include monoclonal gammopathy of undetermined significance (MGUS), multiple myeloma (MM), lymphoplasmacytic lymphoma or Waldenstrom macroglobulinemia  (LPL/WM), lymphoproliferative<unk> s, smoldering multiple myeloma (SMM); solitary or extramedullary<unk> cytoma,  amyloidosis, and POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes). These<unk> s have been defined by the International Myeloma Working Group in 2006.
Plasma cell disorder
Secondary amyloidosis
Myeloproliferative neoplasm
Autoimmune lymphoproliferative syndrome
Tumor induced osteomalacia
Vitamin D deficiency
Monoclonal gammopathy of undetermined significance
Primary cutaneous amyloidosis