<unk>  treatment is required for patients who are annoyed by wheals appearance and pruritus. First line treatment is H1 antihistamine<unk> ions, such as diphenhydramine, hydroxyzine, cetirizine and other H1 antihistamine. Some patients might require high doses of antihistamines for a complete control of their symptoms, but fortunately it's high doses are tolerated by most patients. If antihistamines as the first line treatment didn't successfully controlled the symptoms, omalizumab and cyclosporine should be tried as the second line treatment. Omalizumab has been effective in different sub-types of<unk> , such as solar<unk> , cold<unk> , cholinergic<unk> ,<unk> l vasculitis and symptomatic dermatographic<unk> . There are some other alternatives if the aforementioned<unk> ions didn't help, alternatives such as dapsone, hydroxychloroquine, sulfasalazine, colchicine, methotrexate, intravenous gamma globulin, plasmapheresis, corticosteroids, H2 antagonists and leukotriene antagonists. Some studies recommended specific alternative treatment for each subtypes of<unk> .
Urticaria medical therapy
Rhinitis medical therapy
Conjunctivitis medical therapy
Listeriosis medical therapy
Impetigo medical therapy
Cough medical therapy
Yaws medical therapy
Measles medical therapy