The Amplatzer septal<unk>  (ASO) is currently the most widely used<unk> because it is easy to implant and has high success rates. It first came to be used for human subjects in 1995. However, the<unk> is still not approved for usage in<unk>  closure of primum, sinus venosus and  coronary sinus type of<unk>  septal defects.
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