<unk>  acidemia<unk> <unk>  (or<unk>  Aciduria", "GA1", or "GAT1")  is an inherited disorder in which the body is unable to breakdown completely the amino acids lysine, hydroxylysine and tryptophan. Excessive levels of their intermediate breakdown products<unk>  acid, glutaryl-CoA, 3-hydroxyglutaric acid, glutaconic acid) can accumulate and cause damage to the brain (and also other organs), but particularly the basal ganglia, which are regions that help regulate movement.<unk>  causes secondary carnitine deficiency, as<unk>  acid, like other organic acids, is detoxified by carnitine. Mental retardation may also occur.
Glutaric aciduria type 1
Alkaptonuria
Homocystinuria
Essential fructosuria
Phenylketonuria
3-Methylglutaconic aciduria
Mevalonic aciduria
Argininosuccinic aciduria