Aspergillus is primarily transmitted to the human host by inhalation of airborne conidia (usually by dust exposure during building renovation or construction) or contaminated biomedical devices. Aspergillus is not transmitted from one individual to another. The pathogenesis of aspergillosis varies according to the associated clinical syndrome. Allergic bronchopulmonary aspergillosis and allergic Aspergillus rhinosinusitis are thought to be caused by both type I and type III hypersensitivity responses. Aspergilloma, chronic pulmonary aspergillosis, and invasive aspergillosis are directly related to the growth and expansion of the Aspergillus hyphae in the lungs. Lastly, cutaneous aspergillosis may result either from direct access of the Aspergillus through a skin break (primary) or dissemination of the Aspergillus to the skin from a distant infected organ (secondary).
Aspergillosis pathophysiology
Aspergillosis diagnostic criteria
Tuberculosis pathophysiology
Mucormycosis risk factors
Coccidioidomycosis pathophysiology
Mucormycosis diagnostic criteria
Mucormycosis pathophysiology
Blastomycosis pathophysiology