<unk>  is a clinical state where there is reduced production of adrenocortical hormones. The<unk>  cortex is divided into three zones- zona glomerulosa, zona fasciculata and zona reticularis producing mineralocorticoids, glucocorticoids and androgens respectively.<unk>  can cause glucocorticoid and mineralocorticoid deficiency. It is classified as primary, secondary and tertiary. Its presentation depends on the rapidity and degree of hormone depletion. It can present acutely as<unk>  crisis, especially when the body is under stress due infections, trauma etc. If it presents chronically, it is called Addison's disease. The common causes include chronic glucocorticoid use and autoimmune<unk> itis. It is diagnosed using serum basal cortisol measurement and ACTH stimulation test.  Treatment consists of lifelong glucocorticoid and mineralocorticoid replacement.
Adrenal insufficiency
Adrenal fatigue
Adrenal atrophy
Precocious puberty
Hypogonadism
Adrenal hemorrhage
Thyroid storm
Ototoxicity