<unk>  lymphoma (HL) is a neoplasm characterized by involving lymph nodes and the lymphatic system, and is classified according to WHO classification into two major subgroups: nodular lymphocyte predominant and classic<unk> 's lymphoma. Classic<unk> 's lymphoma is further divided into four subtypes: nodular sclerosis , mixed cellularity , lymphocyte rich, and lymphocyte .<unk>  lymphoma is characterized by the presence of multinucleated giant cells Reed-Sternberg cells, derived from germinal center or postgerminal center B cells. In all four subtypes of classic<unk>  lymphoma the Reed-Sternberg cells have a similar immunophenotype. Whereas in the NLPHL the Reed-Sternberg cells have a distinctive B-cell immunophenotype. On gross pathology, white-grey, uniform, and enlarged lymph nodes are characteristic findings of<unk> 's lymphoma. On microscopic histopathological analysis, Reed-Sternberg cells, reactive cell infiltrate, and complete or partial effacement of the lymph node architecture are characteristic findings of<unk> 's lymphoma.
Hodgkin's lymphoma pathophysiology
Non-Hodgkin lymphoma pathophysiology
Burkitt's lymphoma pathophysiology
B-cell lymphoma risk factors
B-cell lymphoma pathophysiology
Follicular lymphoma risk factors
Lymphoplasmacytic lymphoma risk factors
Diffuse large B cell lymphoma risk factors