<unk>  are characterized by spontaneous inflammation, due to the over activation of innate immunity, which occur without any predisposing infections or<unk> immunity<unk> . These<unk>  can be broadly classified into type types; hereditary and acquired.<unk>  which are related to primary immunodeficiency diseases belong to the hereditary type. Although immunodeficiency and<unk> -inflammation are separate entities, situations can occur when both inflammation and infections coexist. Hence, it is important to rule out infections when diagnosing<unk>  in immunodeficiency.
Auto-inflammatory disorders
Systemic autoimmune diseases
Idiopathic
Scleroderma risk factors
Spondylopathies
Diseases of immune dysregulation
Inflammatory dermatoses
Immunoproliferative disorders