Glycine encephalopathy, also known as non-ketotic hyperglycinemia or NKH, is an autosomal recessive metabolic disorder characterized by abnormally high levels of the amino acid glycine. Glycine acts as a neurotransmitter, which is a chemical messenger that transmits signals in the brain.
Glycine encephalopathy is caused by the shortage of an enzyme that normally breaks down glycine in the body. A lack of this enzyme allows excess glycine to build up in tissues and organs, particularly the brain, leading to serious medical problems.
D-Glyceric acidemia
Galactosemia
Dysbetalipoproteinemia
Hypobetalipoproteinemia
Abetalipoproteinemia
Glycosuria
Isovaleric acidemia
Glucosuria