<unk> s are<unk> s that become large as a result of antigen stimulation. Typically they can be more than 30 µm in diameter with varying size and shape.
The nucleus of a<unk>  can be round, elliptic, indented, cleft or folded. The cytoplasm is often abundant and can be basophilic. Vacuoles and/or azurophilic granules are also sometimes present. Most often the cytoplasm is gray, pale blue or deep blue in colour.
The distinctive cell associated with EBV or CMV is known as a "Downey cell", after Hal Downey, who contributed to the characterization of it in 1923. It is sometimes erroneously called a "Downy cell".
Reactive lymphocyte
Plasma cell
Histiocyte
Dendritic cell
T cell
Koilocyte
Monocyte
Follicular dendritic cells