Incidence of SMA – 1 in 6,000 – 10,000 live births or 7.8-10 per 100,000 live births .
Carrier frequency for SMN 1 gene mutation is 1:38 to 1:50. , ,  , 
7.5 million Americans are carriers.
A 2005 study in Cuba found a reduced incidence of Type I SMA amongst the Cuban population overall, (3.53 per 100,000 live births) and especially amongst those of African ancestry (0.89 to 0.93 per 100,000 live births) .
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