<unk> (vaginal) is an endocrine-metabolic agent that is FDA approved for the treatment of vulval and vaginal atrophy. There is a Black Box Warning for this drug as shown here.  Common adverse reactions include Edema, Chloasma, Hirsutism, Bloating, Nausea, Stomach cramps, Vomiting, Headache, Migraine, Depression, Breast tenderness, Disorder of menstruation.
Estropipate 
Progabide
Troxipide
Fipexide
Rimiterol
Sermorelin
Celiprolol
Tesamorelin