<unk>  1 and 2 <unk> -1 and<unk> -2) are two strains of the<unk>  virus family,<unk> viridae, which cause extremely painful infections in humans. They are also called Human<unk>  Virus 1 and 2 (HHV-1 and HHV-2).
An infection is marked by watery blisters in the skin or mucous membranes (such as the mouth or lips) or on the genitals. Lesions heal with a scab characteristic of<unk> ic disease. However, the infection is persistent and symptoms may recur periodically as outbreaks of sores near the site of original infection.  After the initial, or primary, infection,<unk>  becomes latent present in the cell bodies of nerves in the area.  When it becomes reactivated, it is produced in the nerve cell and transported to the skin via the nerve's axon.<unk>  is contagious if the carrier is producing and shedding virus. This is especially likely during an outbreak but possible at other times.  There is no cure yet, but there are treatments which reduce the likelihood of viral shedding. An<unk>  infection on the lips is commonly known as a "cold sore" or "fever blister".  The blisters resemble those of chickenpox, an infection caused by another member of the alpha-Herpesviridae subfamily, Varicella Zoster Virus (VZV), also known as Human<unk>  Virus 3 (HHV-3).
Herpes simplex virus
Cytomegalovirus
Human papillomavirus
Varicella zoster virus
Smallpox virus
Treponema pallidum
Parvovirus B19
Rubella virus