<unk>  (paramethoxyamphetamine, p-methoxyamphetamine or 4-methoxyamphetamine) is a synthetic phenethylamine drug, psychostimulant and hallucinogen. It is commonly sold as "Ecstasy" and both dealers and users are likely to be unaware that a particular batch of pills contains<unk>  rather than MDMA. Notable batches of pills containing<unk>  have included Mitsubishi Turbo or Red/Blue Mitsubishi and Yellow Euro pills.<unk>  is often synthesized from anethole, the flavor compound of anise and fennel, mainly because the starting material for MDMA, safrole has become less available due to law enforcement action, causing illicit drug manufacturers to use anethole as an alternative. Once thought to be a human invention , recent research suggests<unk>  occurs as a trace alkaloid in plants including certain Acacia species. . It is classified as a Schedule I hallucinogen under the Controlled Substances Act in the United States. Internationally,<unk>  is a Schedule I drug under the Convention on Psychotropic Substances .<unk>  has been associated with numerous adverse reactions including death. Effects of<unk>  ingestion include many effects of the hallucinogenic amphetamines including accelerated and irregular heartbeat, blurred vision, and a strong feeling of intoxication which is often unpleasant. While<unk>  can reportedly be euphoric at low doses, the dose-response curve is much steeper than that of MDMA, and at higher doses unpleasant effects such as nausea and vomiting, severe hyperthermia and hallucinations quickly overpower any pleasurable effects. The effects of<unk>  also seem to be much more unpredictable and variable between individuals than those of MDMA, and sensitive individuals may die from a dose of<unk>  that a less susceptible person might only be mildly affected by. There are approximately twice as many deaths caused by<unk>  as by MDMA, even though the actual proportion of<unk>  on the market is only a fraction of that of MDMA.  While<unk>  alone may cause significant toxicity, the combination of<unk>  with MDMA has a synergistic effect which seems to be particularly hazardous. Since<unk>  has a slow onset of effects, several deaths have occurred where individuals have taken a pill containing<unk> , followed by a pill containing MDMA some time afterwards due to thinking that the first pill was not active.
It appears that<unk>  elevates body temperatures dramatically; the cause of this property is suspected to be related to its ability to inhibit monoamine oxidase A and at the same time releasing large amounts of serotonin, effectively causing serotonin syndrome .  Amphetamines, especially serotonergic analogues such as MDMA, are strongly contraindicated to take with MAOIs.  Many amphetamines and adrenergic compounds raise body temperatures; whereas some tend to produce more euphoric activity, or peripheral vasoconstriction, or tend to favor one effect over another, it appears that<unk>  activates the hypothalamus much more strongly than MDMA and other drugs like ephedrine, thereby causing rapid increases in body temperature (which is the major cause of death in<unk>  mortalities). Many people taking<unk>  try to get rid of the heat by taking off their clothes, taking cold showers or wrapping themselves in wet towels, and even sometimes by shaving off their hair.
Because<unk>  is given out through the same venues and distribution channels that "Ecstasy" tablets are, the risk of being severely injured, hospitalized or even killed from use of Ecstasy increases significantly when a batch of "Ecstasy" pills containing<unk>  starts to be sold in a particular area.<unk>  pills could be a variety of colours or logos, and there is no way of knowing just from the appearance of a pill what drugs it might contain. . Due to the variations in street "Ecstasy" pills, the only way to reduce the risk of ingestion of<unk>  is to test any "Ecstasy" pill that is bought with a pill testing kit before it is consumed, and to monitor reported results from police or government drug testing laboratories and avoid any pills that are reported to contain<unk> .
Four analogues of<unk>  have been reported to be sold on the black market: PMMA, PMEA , 4-ETA and 4-MTA.  These are the N-methyl, N-ethyl, 4-ethoxy and 4-methylthio analogues of<unk> , respectively. PMMA and PMEA are reportedly weaker, more "ecstasy-like" and somewhat less dangerous than<unk>  itself, but can still produce nausea and hyperthermia similar to that produced by<unk> , albeit at slightly higher doses. 4-ETA was briefly sold in Canada in the 1970s but little is known about it.  4-MTA however is more dangerous even than<unk>  and produces strong stimulant effects and intense hyperthermia, but with little euphoria, and was implicated in several deaths in the late 1990s.
PMA
G-LOC
ALARA
Pro-ana
EVAR
HM 
MMDA 
SeHCAT