<unk> es are conditions which cause impairment of<unk> <unk> ty, which can lead to<unk> deficiency. It can be mediated by failures of B cells, the plasma cells they differentiate into, or the antibody secreted by the plasma cells.
They are associated with increased vulnerability to infection, but can be difficult to detect (or asymptomatic) in the absence of infection.
They can be associated with increased risk of gastric cancer.
Humoral immune deficiency
Congenital defects of phagocytes
Defects in intrinsic and innate immunity
Natural killer cell deficiency
IgG deficiency
Complement deficiencies
Complement deficiency
Primary immunodeficiency