<unk>  (INN), formerly bendrofluazide (BAN), trade name Aprinox, is a thiazide diuretic used to treat hypertension.<unk>  is a thiazide diuretic which works by inhibiting sodium reabsorption at the beginning of the distal convoluted tubule (DCT). Water is lost as a result of more sodium reaching the collecting ducts.<unk>  has a role in the treatment of mild heart failure although loop diuretics are better for reducing overload. The main use of<unk>  currently is in hypertension (part of the effect is due to vasodilation).
Common adverse effects:
postural hypotension
hyponatraemia, hypokalaemia, hypercalcaemia
gout
impaired glucose tolerance
impotence
Rare adverse effects:
thrombocytopenia
agranulocytosis
pancreatitis
Bendroflumethiazide
Hydroflumethiazide
Trichlormethiazide
Anetholtrithione
Periciazine
Thiazinam
Clomethiazole
Guanoclor