Observation is recommended for all pediatric patients with an isolated<unk>  cell<unk>  skin involvement. Medical therapy is suggested only for symptomatic cutaneous disease that presents with either extensive rash, sever pain, skin ulceration, or bleeding. Medical therapies used for the treatment of isolated skin lesions of<unk>  cell<unk>  include topical steroids, nitrogen mustard, and oral thalidomide. Curettage is the mainstay treatment for single skull lesions that involve the frontal, parietal, or occipital bones. The most commonly used systemic chemotherapy regimen for the management of multiple bone lesions is a combination of vinblastine AND prednisone. The standard therapy recommended for<unk>  cell<unk>  involving the spleen, liver, or bone marrow (high-risk organs) consists of vinblastine AND prednisone AND 6-mercaptopurine for a 12 month period.
Langerhans cell histiocytosis medical therapy
Thymoma medical therapy
Diffuse large B cell lymphoma medical therapy
Hodgkin's lymphoma medical therapy
Thymoma radiotherapy
POEMS syndrome medical therapy
Thymic carcinoma medical therapy
Kaposi's sarcoma medical therapy