The incidence ZD is approximately 2 per 100,000 individuals worldwide, The prevalence of ZD is between 10 to 110 per 100,000 individuals worldwide. The mortality rate is 300 individuals per 100,000 individuals for stapled rigid endoscopic procedures. Mortality rate for non-stapled rigid endoscopic procedures is 200 individuals per 100,000 individuals. ZD commonly affects middle-aged and elderly individuals, especially people in their 7th and 8th decades.There is no racial predilection to ZD. Males are more commonly affected by ZD than females. The men to women ratio are approximately 1.5 to 1. The majority of ZD cases are reported in northern Europe.
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