<unk>  is a disease of the central nervous system caused by infection from Naegleria fowleri. Naegleria fowleri is a free-living ameboflagellate that invades the brain and meninges via the nasal mucosa and olfactory nerve to cause acute, fulminant hemorrhagic<unk>  <unk>  –<unk> ,<unk> ly in healthy children and young adults with a recent history of exposure to warm fresh water. Initial signs and symptoms of<unk>  begin 1 to 14 days after infection and include sudden onset of headache, fever, nausea, vomiting, and stiff neck accompanied by positive Kernig’s sign and Brudzinski’s sign. In some cases, abnormalities in taste or smell, nasal obstruction and nasal discharge might be seen. Other symptoms might include photophobia, mental-state abnormalities, lethargy, dizziness, loss of balance, other visual disturbances, hallucinations, delirium, seizures, and coma. After the onset of symptoms, the disease progresses rapidly and usually results in death within 3 to 7 days. Although a variety of treatments have been shown to be active against amoebae in vitro and have been used to treat infected persons, most infections have still been fatal.
Primary amoebic meningoencephalitis
Granulomatous amoebic encephalitis
Fungal meningitis
Eastern equine encephalitis
Japanese encephalitis
Rasmussen's encephalitis
Herpes simplex encephalitis
La Crosse encephalitis