Preeclampsia may be the result of placental factors in maternal circulation leading to endothelial dysfunction, hypertension, and proteinuria. Increased levels of  an angiogenic factor named fms-like tyrosine kinase 1 in the placenta is correlated  with endothelial dysfunction. In villous trophoblast of preeclamptic women, apoptosis was considered. Following uteroplacental ischemia, and invasion spiral arteries by trophoblasts, releasing some angiogenic factors causes other organ involvement. Incomplete penetration in recessive or dominant genes was noticed in pathogenesis of preeclampsia.
Pre-eclampsia pathophysiology
Pre-eclampsia causes
Pre-eclampsia risk factors
Hyperemesis gravidarum pathophysiology
Antiphospholipid syndrome risk factors
Pre-eclampsia differential diagnosis
Endometrial hyperplasia risk factors
Endometriosis risk factors