<unk>  is a pathogenic bacterium that causes<unk>  It is a facultatively anaerobic, gram positive organism characterized by non-encapsulated, non-sporulated, immobile, straight or curved rods. The genome of<unk>  contains 2,488,635 nucleotides, 2,389 genes, and  69 structural RNA genes. Gram-stain will result in a blue-purple coloration due to containing polymetaphosphate granules. Many strains of<unk>  produce<unk> toxin, a protein exotoxin, with a molecular weight of 62 kilodaltons which ADP-ribosylates host EF-2, resulting in the inhibition of protein synthesis and producing signs of<unk>  C.<unk>  is exclusively pathogenic in humans.<unk>  can be classified into following four subspecies: mitis, intermedius, gravis, and belfanti. The diagnosis of<unk>  includes a Gram stain procedure; results will indicate gram-positive, pleomorphic bacteria that will dye violet-blue and resemble clubs.<unk>  causes<unk> disease in non-immunized human hosts via secreted toxins. Toxigenic strains of the bacterium will secrete toxins in nasopharyngeal or skin lesions. It is common for hosts to carry<unk>  in the nasopharyngeal region without displaying symptoms. Lysogenic conversion of nontoxigenic-toxigenic phenotypes of the bacterium can occur following transmission, allowing non-human/affected hosts to transmit<unk> to humans.<unk>  is sensitive to antibiotic therapy.
Corynebacterium diphtheriae
Bacillus anthracis
Streptococcus pyogenes
Rhodococcus equi
Pseudomonas aeruginosa
Mycobacterium avium intracellulare
Mycobacterium tuberculosis
Fusobacterium necrophorum