<unk>  ( also known as<unk>  cell lung cancer") is a type of non-small cell carcinoma of the lung. It is the second most commonly encountered lung cancer after lung adenocarcinoma.<unk>  cell carcinoma accounts for 30-35% of all lung cancers and has a strong association with smoking.<unk>  may be classified according to the WHO histological classification system into 4 main types: papillary, clear cell, small cell, and basaloid.<unk>  arises from the epithelial cells of the lung from the central bronchi to the terminal alveoli, which are normally involved in the protection of the airways.<unk>  has a central location and usually appears as a hiliar or perihiliar mass.<unk>  is a rapidly growing cancer which may metastasize to various organs of the body. Genes involved in the pathogenesis of<unk>  cell carcinoma include EGFR, EML-4, KRAS, HER2, and ALK. Common causes of<unk>  include precursor lesions, such as metaplasia or dysplasia induced by smoking, asbestos exposure, ionizing radiation, atmospheric pollution, and chronic interstitial pneumonitis. Less common causes of non-small cell lung cancer include chromium and nickel exposure, vinyl chloride exposure, and inorganic arsenic exposure. The optimal treatment management of<unk>  will depend on several characteristics, such as pre-treatment evaluation (performance status), location, and adequate staging. Common medical treatment options for the management of<unk>  include chemotherapy (neoadjuvant/adjuvant) and radiation therapy. Surgery is the mainstay of treatment for<unk> . Common surgical procedures for the treatment of<unk>  include pulmonary lobectomy, pneumonectomy, lung resection with lobectomy, or lung resection with pneumonectomy with or without lymph node dissection. The preferred surgical procedure is thoracotomy with removal of the entire lung or lobe (lobectomy) along with regional lymph nodes and contiguous structures. Prognosis of<unk>  is generally regarded as poor, with the average survival rate ranging from 16% to 49%.
Squamous cell carcinoma of the lung
Large cell carcinoma of the lung
Adenocarcinoma of the lung
Sarcomatoid carcinoma of the lung
Non small cell lung cancer
Small cell carcinoma of the lung
Bronchoalveolar carcinoma
Bronchioloalveolar carcinoma