<unk>  (INN) (abbreviated norepi or NE) 
or noradrenaline (BAN) (abbreviated<unk>  or<unk> d) is a catecholamine with multiple roles including as a hormone and a neurotransmitter.
As a stress hormone,<unk>  affects parts of the brain where attention and responding actions are controlled. Along with epinephrine,<unk>  also underlies the fight-or-flight response, directly increasing heart rate, triggering the release of glucose from energy stores, and increasing blood flow to skeletal muscle.<unk>  can also suppress neuroinflammation when released diffusely in the brain from the locus ceruleus.
When<unk>  acts as a drug it increases blood pressure by increasing vascular tone through α-adrenergic receptor activation. The resulting increase in vascular resistance triggers a compensatory reflex that overcomes its direct stimulatory effects on the heart, called the baroreceptor reflex, which results in a drop in heart rate called reflex bradycardia.<unk>  is synthesized from dopamine by dopamine β-hydroxylase. It is released from the adrenal medulla into the blood as a hormone, and is also a neurotransmitter in the central nervous system and sympathetic nervous system where it is released from noradrenergic neurons. The actions of<unk>  are carried out via the binding to adrenergic receptors.
Norepinephrine
Dopamine
Synephrine
Octopamine
Aldosterone
Hyoscyamine
Acetylcholine
Angiotensin II 