<unk>  (also known as hyperlipidemia or high lipoproteins) is defined as presence of high levels of one or more type of lipoproteins.<unk>  may be caused by primary genetic disorders or as a secondary complications of underlying medical conditions. After ruling out common secondary causes of<unk> , the clinician must begin the work-up for primary causes.
Patients with<unk>  may present with elevated LDL, HDL, or triglycerides.<unk> s have a high clinical significance due to the increased risk of cardiovascular, cerebrovascular, and peripheral arterial disease which they confer. Other complications of long-standing hyperlipidemia (specifically hypertriglyceridemia) may include pancreatitis, and steatohepatitis.
Primary causes of<unk>  have been classified into 5 subtypes by Friedrickson. The exact genetic cause of these conditions is not clearly understood. Secondary causes of<unk>  are more common and workup must be targeted at excluding them prior to evaluating primary causes. Regardless of the underlying pathogenesis of the disease, management is targeted at normalizing the affected lipid or lipoproteins either pharmacologically or by lifestyle modifications. However, gene therapy has been a subject of several investigational therapies aiming to treat familial<unk> s at the genomic level.
Hyperlipoproteinemia
Hypolipoproteinemia
Hypertriglyceridemia
Analbuminaemia
Neutrophilia
Dyslipidemia
Hypocholesterolemia
Lipiduria