<unk>  is a condition of altered intestinal water and electrolyte transport. The pathophysiology of acute<unk>  includes osmotic, secretory, inflammatory types, and<unk>  due to altered motility. Acute<unk>  due to osmotic causes includes osmotic laxatives such as lactose intolerance, antacids, fructose, lactulose, and increased concentration of magnesium, phosphate, and sorbitol, which induce a secretory state. Bacterial infection of the intestine leads to activation of epithelial ion channels with increased secretion of anions. Invasion of the epithelium by various pathogens lead to exotoxin production and enhancement of enterocyte secretion by cytotoxins or intracellular signalling. In case of motility disorders of the gut, rapid transit time delivers fluid secreted during digestion to the distal small bowel or colon. This prevents reabsorption of normally secreted fluid in the small bowel, overwhelming the reabsorptive capacity of the colon.
Acute diarrhea pathophysiology
Gastrointestinal perforation pathophysiology
Secondary peritonitis pathophysiology
Acute mesenteric ischemia pathophysiology
Spontaneous bacterial peritonitis pathophysiology
Mesenteric ischemia pathophysiology
Ileus pathophysiology
Diverticulitis pathophysiology