Autosomal dominant<unk>  (ADPKD), previously known as adult<unk> , is a systemic disorder characterized primarily by multiple, bilateral renal cysts, cysts in other organs namely the liver and pancreas, and cardiovascular abnormalities including intracranial aneurysms and mitral valve prolapse. ADPKD is one of the most common inherited disorders worldwide almost 15 times more common than cystic fibrosis in the general population.  It accounts for up to 3-5% of ESRD cases yearly. Classically, ADPKD presents with hypertension and varying degrees of renal insufficiency. Around half of the patients diagnosed with ADPKD will reach end-stage renal disease (ESRD) by the age of 60 years. Still, disease manifestation and severity is highly variable among patients even those within the same family.
Polycystic kidney disease
Renal amyloidosis
Medullary cystic kidney disease
Medullary sponge kidney
Shunt nephritis
Glomerulonephrosis
Lupus nephritis
Membranous nephritis