It is understood that<unk><unk>  dystrophy is the result of genetic mutation of dystrophin gene located on X-chromosome.<unk><unk>  dystrophy arises from muscle cells, which are  involved in<unk>  contraction. Dystrophin protein is a part of the protein complex named dystrophin-associated protein complex (DAPC) which acts as an anchor that connect the intracellular cytoskeleton proteins such as α-dystrobrevin, syncoilin, synemin, sarcoglycan, dystroglycan, and sarcospan to the extracellular matrix. On microscopic histopathological analysis, replacement of muscle by fat and connective tissue, muscle degeneration, muscle regeneration, and opaque hypertrophic fibers are characteristic findings of<unk><unk>  dystrophy.
Duchenne muscular dystrophy pathophysiology
Laing distal myopathy
Duchenne muscular dystrophy laboratory findings
Cerebral palsy pathophysiology
Amyotrophic lateral sclerosis pathophysiology
Spinal muscular atrophy risk factor
Lesch-Nyhan syndrome pathophysiology
Congenital myopathy