HCM is the most common genetically transmitted cardiovascular disease.  Hypertrophic<unk>  is inherited as an autosomal dominant trait and is attributed to mutations in one of a number of genes that encode for one of the sarcomere proteins .  Penetrance of HCM is incomplete, variable and time or age-related.  The disease may be sporadic but affected family members are discovered in 13% of cases.  More than 200 mutations involving at least 10 chromosomes encoding structural proteins of the myocyte have been discovered.  These mutations have varying degrees of penetrance and even the same mutation may have variable expression, implying superimposed effects of other genes or environmental influences.   Children of a patient with HCM have a 50% chance of inheriting the trait.
Hypertrophic cardiomyopathy genetics
Noncompaction cardiomyopathy genetics
Hypertrophic cardiomyopathy classification
Hypertrophic cardiomyopathy electrocardiogram
Eisenmenger’s syndrome electrocardiogram
Hypertrophic cardiomyopathy histopathology
Hypertrophic cardiomyopathy laboratory findings
Noncompaction cardiomyopathy embryology