<unk>  (BRE) is the second most frequent type of postoperative endophthalmitis.<unk>  is a complication of trabeculectomy. The exact pathogenesis of<unk>  following trabeculectomy is not fully understood. It is thought that<unk>  is the result of<unk>  leakage, which allows bacterial entry from the tear film and the periocular structures into the anterior chamber or the vitreous humor.
Based on latency of onset,<unk>  (BRE) may be classified into early onset and late onset. Common causes of<unk>  include Streptococcus spp., Staphylococcus spp., and Haemophilus influenzae. Common risk factors for the development of<unk>  include<unk>  leakage, inappropriate use of  antifibrotic agents such as 5-fluorouracil (5-FU) and mitomycin C, inferior and nasal placement of<unk> , and prior history of<unk> itis.<unk>  is a medical emergency. If left untreated, it may lead to corneal infiltration, retinal toxicity, corneal perforation, retinal detachment, and panophthalmitis that may require enucleation.<unk>  presents as an accelerated prodromal syndrome, which can progress rapidly over several hours. It is usually characterized by severe visual loss and marked pain.
Endophthalmitis is a clinical diagnosis supported by culture and polymerase chain reaction (PCR) of intra-ocular fluids.
Patients with<unk>  need urgent examination by an expert ophthalmologist and/or vitreo-retinal specialist. Intravitreal injection of antibiotics, topical fortified antibiotics, and surgical repair are necessary in the management of<unk> . However, the benefit of vitrectomy in the management of<unk>  remains unclear. Assessment of<unk>  leakage following trabeculectomy surgery in every visit seems to be the most effective measure for the primary prevention of<unk> .
Bleb-related endophthalmitis
Post-traumatic endophthalmitis
Endogenous endophthalmitis
Bacterial endophthalmitis
Post-operative endophthalmitis
Post-cataract surgery endophthalmitis
Fungal keratitis
Herpes simplex ocular infection