<unk>  is a rare highly specific and characteristic paraneoplastic syndrome that usually affect older people. It is characterized by wood-grain scaly skin eruption with intense pruritus. The cause of<unk>  is unknown but many theories suggest immunologic etiology or toxicologic products that are released by the associated tumor. The first case of<unk>  was described by a  dermatologist named Gammel in the year 1952. For many years after<unk>  original description, there was little progress in defining the pathogenesis of<unk> .<unk>  has no specific classification but we can classify it based on its association with an internal malignancy into para-neoplastic and non-para-neoplastic<unk> . The most common malignancies associated with<unk>  are lung or bronchogenic cancer, esophageal cancer, and breast cancer.<unk>  can also be associated with non-neoplastic diseases such as tuberculosis, autoimmune disorders, or CREST syndrome.<unk>  is characterized by its pathogonomic figurate, gyrate, or annular<unk> tous skin eruptions. The intense pruritus can be debilitating and usually urges the patient to go to the emergency department. The microscopic histopathological features of<unk>  consist of acanthosis, focal parakeratotic, and spongiosis of the epidermis with perivascular mononuclear, lymphocytic, and histiocytic infiltrate in the superficial plexus of the dermis.<unk>  is very rare and it mainly affects people in their seventieth decade, the male to female ratio is 2:1.<unk>  is diagnosed clinically by its characteristic skin eruption and an urgent thorough paraneoplastic workup should be initiated to look for internal malignancies. Patients with<unk>  presents with intensely pruritic, gradually progressive, skin lesions that crawl rather than migrate from one body region to the other. It can start in the upper trunk or upper back and extends to involve the extremities sparing the face. The mainstay of the treatment of<unk>  is finding and treating the underlying malignancy. Symptomatic treatment is not very effective in relieving the pruritus and its associated pain. The management can be surgical removal of the tumor, chemotherapy, or palliative conservative management. The skin eruptions can improve completely after the removal of the underlying tumor, or can recur especially if the tumor recurred or metastasized. Patients can live a few weeks, months or up to five years depending on when and at what stage the malignancy was detected.
Erythema gyratum repens
Pityriasis rosea causes
Pseudoxanthoma elasticum causes
Acrodermatitis chronica atrophicans causes
Vesicular and bullous lesions
Pigmented lesions
Dermatophytosis causes
Stevens-Johnson syndrome causes