Persons with<unk>  syndrome do not make a substance called lysosomal alpha-L-iduronidase. This substance, called an enzyme, helps break down long chains of sugar molecules called glycosaminoglycans (formerly called mucopolysaccharides). These molecules are found throughout the body, often in mucus and in fluid around the joints.
Without the enzyme, glycosaminoglycans build up and damage organs, including the heart.
Hurler syndrome causes
Noonan syndrome causes
Fanconi syndrome causes
Sezary syndrome causes
Cowden syndrome causes
Adams-Stokes syndrome causes
Pott's disease causes
Plummer-Vinson syndrome causes