<unk>  <unk> , also known as chronic kidney<unk>  (CKF) or chronic kidney disease (CKD), or chronic renal insufficiency (CRI) is a slowly progressive loss of renal function over a period of months or years defined as an abnormally low glomerular filtration rate.  The glomerular filtration rate is usually determined indirectly by the creatinine level in blood serum.<unk>  that leads to severe illness and requires some form of renal replacement therapy (such as dialysis) is called end-stage renal disease (ESRD).
Definition
CKD is defined as:
Presence of markers of kidney damage for  > 3 months, and may include abnormalities in markers in blood or urine, and imaging tests.
GFR < 60 mL/min/1.73 m2 for > 3 months with or without other signs of kidney damage.
Presence of markers of kidney damage for  > 3 months, and may include abnormalities in markers in blood or urine, and imaging tests.
GFR < 60 mL/min/1.73 m2 for > 3 months with or without other signs of kidney damage.
Chronic renal failure
Chronic liver disease
Chronic hypertension
Cirrhosis
Renal amyloidosis
Prediabetes
Old age
Pediatric end-stage liver disease