<unk>  refers to a form of<unk>  where the presentation appears in the lower limbs before the upper limbs.
It can be associated with:
Guillain-Barré syndrome (another name for this condition is "Landry's<unk> ")
Tick<unk> 
It can be contrasted to "descending<unk> ", which occurs in conditions such as botulism.
Ascending paralysis
Spinal autonomic dysreflexia
Cycloplegia
Fasciculation
Transverse myelitis pathophysiology
Acute motor axonal neuropathy
Amyotrophic lateral sclerosis pathophysiology
Neuromyotonia