<unk>  is the second most common subtype of mutations within long QT syndrome, occurring in 35-45% of LQTS patients. This subtype has been known to come to the attention of the cardiologist as a result of a cardiac event during the post-partum period, or after being triggered by an alarm clock or other auditory stimuli. The<unk>  mutation involves the HERG gene on chromosome 7, which regulates the channel responsible for the  potassium rectifying current, which terminates the cardiac action potential. Most drugs that cause acquired long QT syndrome, do so by blocking the potassium rectifying current via the HERG gene. These drugs include antiarrhythmic drugs, certain non-sedating antihistamines, macrolide antibiotics, certain psychotropic medications, and certain gastric motility agents.
LQT2
LQT1
LQT3
LQT4
LQT5
LQT6
LQT10
LQT8