The pathophysiologic mechanisms leading to<unk>  kidney disease stem from the underlying etiologies responsible for the primary renal damage. Maladaptive systemic and renal responses arise that maintain and perpetuate the existing renal disease. Broadly, 3 main mechanisms exist that are related in part to the activation of the RAAS: hyperfiltration, inflammation, and accelerated fibrosis. As loss of kidney function progresses, nitrogen waste products are no longer cleared by the kidneys, and patients develop uremia as these uremic solutes accumulate over time.
Chronic renal failure pathophysiology
Renal papillary necrosis risk factors
Acute kidney injury pathophysiology
Acute tubular necrosis risk factors
Analgesic nephropathy risk factors
Renal artery stenosis risk factors
Renal amyloidosis risk factors
Congestive heart failure pathophysiology