<unk>  <unk>  is a potentially life-threatening complication observed in patients with acute promyelocytic leukemia (APML) and first thought to be specifically associated with all-trans<unk> <unk>  (ATRA) (also known as tretinoin) treatment.  Subsequently it was recognized that so-called<unk>  appeared in APML patients who had been treated with another highly efficacious drug, arsenic trioxide, and yet did not appear in patients treated with tretinoin for other disorders.  These facts and others support the notion that<unk>  depends on the presence of the malignant promyelocytes.  This has led to the growing deprecation of the term<unk> ' and to an increasing use of the term differentiation syndrome to signify this APML treatment complication.
Retinoic acid syndrome
Hurler syndrome
Silver-Russell dwarfism
Gourmand Syndrome
Hadju Cheney Syndrome
Miller-Dieker syndrome
Down syndrome
Rotor syndrome