<unk>  sclerosis is a disease in which the myelin (a fatty substance which covers the axons of nerve cells, important for proper nerve conduction) degenerates. This includes not only the usually known white matter demyelination, but also demyelination in the cortex and deep gray matter (GM) nuclei, as well as diffuse injury of the normal-appearing white matter. GM atrophy is independent of the MS lesions and is associated with physical disability, fatigue, and cognitive impairment in MS
Pathophysiology of multiple sclerosis
Multiple sclerosis pathophysiology
Dermatomyositis pathophysiology
Adrenoleukodystrophy pathophysiology
Amyotrophic lateral sclerosis pathophysiology
Multiple sclerosis laboratory findings
Adrenoleukodystrophy laboratory findings
Ganglioglioma pathophysiology