<unk>  (bactoCeaze or Ensamycin) is an aminoglycoside antibiotic, isolated from the
fermentation broth of a new species of the genus Micromonospora. It is a newer broad-spectrum aminoglycoside most structurally related to gentamicin.<unk>  is the most predictably active aminoglycoside against gram-positive bacteria. Like most other aminoglycosides,<unk>  is bactericidal for sensitive clinical isolates. The minimum bactericidal concentrations (MBC) have been found to be equivalent or very close to the minimum inhibitory concentrations (MIC). Like other aminoglycosides, most clinical isolates of Pseudomonas aeruginosa remain susceptible to<unk> . Resistance to<unk>  may enzymatically or non-enzymatically be mediated.<unk>  is inactivated by the same enzymes as gentamicin but it is active against many, not all, organisms that resist gentamicin by non-enzymatic mechanisms.
Some studies show that<unk>  has been effective in the treatment of infections that either had failed to respond to other drugs or were due to microorganisms resistant in vitro to other aminoglycosides.
Sisomicin
Micronomicin
Desaspidin
Fidaxomicin
Plazomicin
Rifabutin
Pipemidic acid
Monoxerutin