<unk>  (also known as calcium-alkali syndrome) is characterized by a history of excessive calcium intake and  hypercalcemia, metabolic<unk> sis and varying degrees of renal insufficiency. In 1915, Bertram Sippy introduced a treatment for peptic ulcer disease which was an hourly mixture of<unk>  and cream combined with<unk> ne powders. In 1923, the toxic effects of Sippy’s regimen were reported for the first time. With the introduction of histamine antagonists and decrease in antacid consumption since the 1970s, the incidence of<unk>  has decreased significantly. However, since the 1990s, there has been an increase in<unk>  due to an increase in calcium and vitamin D consumption in postmenopausal women for osteoporosis prevention. Treatment of<unk>  is mostly supportive and mainly includes the withdrawal of the offending agent, hydration, and intravenous volume expansion. Prognosis of<unk>  is generally good and early diagnosis and treatment, with the withdrawal of the offending agent and supportive therapy, usually resolve the symptoms and abnormalities in<unk>  (hypercalcemia,<unk> sis and renal insufficiency).
Milk-alkali syndrome
Refeeding syndrome
Johanson-Blizzard syndrome
Waterhouse–Friderichsen syndrome
Water intoxication
Zollinger-Ellison syndrome
Zieve's syndrome
Selye syndrome