<unk>  is a molecule which is given in combination with beta-lactam antibiotics to inhibit beta-lactamase, an enzyme produced by bacteria that destroys the antibiotics.<unk>  is an irreversible inhibitor of beta-lactamase; it binds the enzyme and does not allow it to interact with the antibiotic.<unk>  is able to inhibit the most common forms of beta-lactamase but is not able to interact with the ampC cephalosporinase. Thus, it confers little protection against bacteria such as Pseudomonas aeruginosa, Citrobacter, Enterobacter, and Serratia, which often express this gene. In the United States,<unk>  is combined to form cefoperazone/sulbactam and ampicillin/sulbactam.  It does possess some antibacterial activity when administered alone, but it is too weak to have any clinical importance.  Its use in the UK is restricted to hospitals.
Sulbactam
Tazobactam
Meropenem
Biapenem
Cefdinir
Vancomycin 
Linezolid
Temocillin