This most recent trial randomly assigned 17,802 healthy subjects with LDL < 130 mg/dL and high-sensitivity CRP > 2 g/L to Rosuvastatin 20 mg daily or placebo. A significant reduction in the composite and individual components of the primary end-point of myocardial infarction, stroke, arterial revascularization hospitalization for unstable angina or death from cardiovascular causes and all-cause mortality was noted and trial was stopped earlier at 1.9 years (maximum of 5 years).
JUPITER Trial
APEX Trial
ASPEN Trial
ACTIVE A Trial
PROSPER Trial
AFCAPS/TexCAPS Trial
Clinical prediction rule
Chronic stable angina COURAGE trial