The<unk>  or node, also called<unk> <unk><unk>  sign, refers to a palpable<unk>  bulging into the umbilicus as a result of metastasis of a malignant cancer in the pelvis or abdomen.
Gastrointestinal malignancies account for about half of underlying sources (most commonly gastric cancer, colon cancer or pancreatic cancer, mostly of the tail and body of the pancreas), and men are even more likely to have an underlying cancer of the gastrointestinal tract.
Gynecological cancers account for about 1 in 4 cases (primarily ovarian cancer and also uterine cancer). Unknown primary tumors and rarely, urinary or respiratory tract malignancies cause umbilical metastases. How exactly the metastases reach the umbilicus remains largely unknown. Proposed mechanisms for the spread of cancer cells to the umbilicus include direct transperitoneal spread, via the lymphatics which run alongside the obliterated umbilical vein, hematogenous spread, or via remnant structures such as the falciform ligament, median umbilical ligament, or a remnant of the vitelline duct.<unk><unk><unk>  is associated with multiple peritoneal metastases and a poor prognosis.<unk>  in a patient with metastatic ovarian cancer
Sister Mary Joseph nodule
Mucoepidermoid carcinoma x ray
Nodular lesions
Hydroa vacciniforme-like lymphoma
Janeway lesions
Lymphoepithelioma
Pyogenic granuloma
Trousseau sign of malignancy