<unk>  <unk>  is an enzyme secreted by several species of streptococci that can bind and activate human plasminogen.<unk>  is used as an effective and inexpensive thrombolysis medication in some cases of myocardial infarction (heart attack) and pulmonary embolism.<unk>  belongs to a group of medications known as fibrinolytics, and complexes of<unk>  with human plasminogen can hydrolytically activate other unbound plasminogen by activating through bond cleavage to produce plasmin. There are three domains to<unk> , denoted α (residues 1–150), β (residues 151–287), and γ (residues 288–414). Each domain binds plasminogen, although none can activate plasminogen independently.
It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Streptokinase
Brinase
Fibrinolysin
Isozyme
Ocriplasmin
Plasminogen
Elastase
Pegademase