Fibroadenoma is a common benign tumor of the breast. Fibroadenoma arises from connective tissue cells, which are cells that are normally involved in the functional and mechanical support of the surrounding tissues. Fibroadenomas may demonstrate estrogen and progesterone sensitivity and may grow during pregnancy. The mediator complex subunit 12 (MED12) gene is the most common gene involved in the pathogenesis of fibroadenoma. On gross pathology, a rubbery, tan colored, and lobulated mass is a characteristic finding of fibroadenoma. On microscopic pathology, charectersitic findings of fibroadenoma include a biphasic proliferation of both stromal and epithelial components that can be arranged in two growth patterns; a pericanalicular growth pattern and an intracanalicular growth pattern.
Fibroadenoma pathophysiology
Mucinous cystadenocarcinoma pathophysiology
Pleomorphic adenoma pathophysiology
Acinic cell carcinoma pathophysiology
Fibroadenoma risk factors
Hepatocellular adenoma pathophysiology
Fibroadenoma epidemiology and demographics
Adrenolipoma pathophysiology