<unk>  is a phenylalanine-metabolizing enzyme that is FDA approved for the reduction of blood phenylalanine concentrations in adult patients with phenylketonuria who have uncontrolled blood phenylalanine concentrations greater than 600 micromol/L on existing management. There is a Black Box Warning for this drug as shown here.  Common adverse reactions include injection site reactions, arthralgia, hypersensitivity reactions, headache, generalized skin reactions lasting at least 14 days, pruritus, nausea, abdominal pain, oropharyngeal pain, vomiting, cough, diarrhea, and fatigue.
Pegvaliase
Tolnaftate
Phenkapton
Gefarnate
Iproclozide
Crofelemer
Pegloticase
Fasudil