<unk>  in<unk>  refers to the<unk>  ion, Li+, used as a drug.<unk>  is administered in a number of chemical salts of<unk> , which are used primarily in the treatment of bipolar disorder as mood stabilizing drugs. In bipolar disorder they have a role in the treatment of depression and particularly of mania - acutely and in the long term. As a mood stabiliser,<unk>  is probably more effective in preventing mania than depression, and may reduce the risk of suicide. In depression alone (unipolar disorder)<unk>  can be used to augment other antidepressants.<unk>  carbonate (Li2CO3), sold as Carbolith®, Cibalith-S®, Duralith®, Eskalith®, Lithane®, Lithizine®, Lithobid®, Lithonate®, Lithotabs® and Maniprex®, is the most commonly prescribed, whilst the citrate salt<unk>  citrate (Li3C6H5O7), the sulfate salt<unk>  sulfate (Li2SO4) sold as Lithionit®, aspartate and the orotate salt<unk>  orotate are alternatives.
Upon ingestion<unk>  becomes widely distributed in the central nervous system and interacts with a number of neurotransmitters and receptors, decreasing norepinephrine release and increasing serotonin synthesis.
Lithium pharmacology
Opioid indications
Short-term effects of alcohol
Antidepressants
Typical antipsychotic
Alcohol withdrawal pathophysiology
Atypical antipsychotics
Tricyclic antidepressant