<unk>  group of infections include: toxoplasmosis, Treponema pallidum , rubella, cytomegalovirus, herpesvirus, hepatitis viruses, Human immunodeficiency virus, and other infections such as varicella, parvovirus B19, and enteroviruses. All of these infections affect the fetus and can cause significant morbidity and mortality. Most of the infections reach the fetus via the transplacental route or by ascending infection. The timing of infection varies  with individual infections to cause severe damage. Most of the infections can result in misscarriage or fetal demise or severe clinical manifestations in the newborn. The infections can compromise normal development during infancy and have poor development. Therefore, early diagnosis and treatment plays an important role in the management of these infections to improve outcomes in the newborn.
TORCH complex
SNARE 
Von Hippel-Lindau tumor suppressor
Cytome
Ankyrin repeat
Rho family of GTPases
SUMO protein
Desmosome