<unk>  is defined as a predilection for clot formation (thrombosis). It could be inherited/genetical or acquired, nevertheless most of the time<unk>  is due to an interplay between both inherited and acquired factors. Protein C deficiency is the most common cause of inherited<unk> . This clot formation tendency can lead to venous or arterial thrombus formation and subsequent conditions such as pulmonary embolism, deep venous thrombosis, pregnancy loss, severe pre-eclampsia, myocardial infarction and stroke. Most of patients with<unk>  may remain asymptomatic until another<unk>  condition has been added and patients with more than one inherited/genetical defects carry higher chance of thrombus formation. Symptoms, if present, are generally depended on organ that is involved. There are numerous causes related to<unk> , such as protein C deficiency, prothrombin gene mutation, Factor V Leiden, protein S deficiency and antiphospholipid syndrome. Nevertheless it is recommended to first rule out acquired causes and look for necessity of further laboratory evaluations. In other words not every patient presented with thrombosis requires<unk>  diagnostic evaluation. Acute thromboembolism management with anticoagulation therapy should be considered for at least 3-6 months, although they are specific cases which need indefinite anticoagulation therapy.
Thrombophilia
Basophilia
Giant platelet disorder
Hemophilia
Essential thrombocytosis
Eosinophilia
Heparin-induced thrombocytopenia
DIC