The sensitivity and the specificity of ANCA testing for pauci-immune glomerulonephritis is only 80-90%, a renal biopsy is crucial for diagnosis of<unk>  progressive glomerulonephritis. It helps to determine the severity of the disease. The initiation of therapy should not be delayed for biopsy results. Renal biopsy specimens show a diffuse, proliferation, necrotizing glomerulonephritis with crescent formation. Immunofluorescence microscopy shows finding of linear deposition of immunoglobulin G (IgG) along the glomerular capillaries and occasionally the distal tubules.
Rapidly progressive glomerulonephritis other diagnostic studies
Lupus nephritis other diagnostic studies
Membranous glomerulonephritis other diagnostic studies
C4 glomerulopathy other diagnostic studies
Renal amyloidosis other diagnostic studies
Renal papillary necrosis other diagnostic studies
Thin basement membrane disease other diagnostic studies
Rapidly progressive glomerulonephritis diagnostic study of choice