<unk>  <unk>  is an inherited systemic disorder that affects the elastic tissue of the skin, retina, gastrointestinal tract, and the cardiovascular system.  It is caused by a mutation of the ABCC6 gene on the short arm of chromosome 16 (16p13.1) that encodes an ATP-binding cassette transporter. <unk>  causes fragmentation and mineralization of elastic fibers in connective tissues and medium-sized arteries.
Pseudoxanthoma elasticum
Keratosis pilaris
Dermatosis neglecta
Lymphangioma circumscriptum
Dermatosis papulosa nigra
Ichthyosis bullosa of Siemens
Nevus anemicus
Nevus comedonicus