<unk>  (marketed under the brand name Hismanal) is a second generation antihistamine drug which has a long duration of action.<unk>  was discovered by Janssen Pharmaceutica in 1977. It has been withdrawn from the market in most countries because of rare but potentially fatal interactions with CYP3A4 enzyme inhibitors (e.g. erythromycin, grapefruit juice).
Astemizole
Azatadine
Alcaftadine
Acetylcysteine 
Hexamidine
Loratadine
Desloratadine
Fomepizole