<unk>  has numerous phenotypes with various clinical findings. The most aggressive one is Childhood cerebral type which results in behavioural changes, school failure, dementia, speech impairment, bulbar palsy, paralysis and audiovisual changes on examination. Most males in childhood have adrenal insufficiency that can show orthostatic hypotension, hyperpigmentation and confusion. Females who are heterozygous and symptomatic can have sphincter disturbances, incoordination and paraparesis.
Adrenoleukodystrophy physical examination
Scleroderma physical examination
Multiple sclerosis physical examination
Sjögren's syndrome physical examination
Dermatomyositis physical examination
Guillain-Barré syndrome physical examination
Undifferentiated connective tissue disease physical examination
Sarcoidosis physical examination