<unk>  arises from the arachnoid "cap" cells, which are normally involved in the protection of the central nervous system by forming a thick envelope of meninges around the brain and spinal cord. The majority of<unk> s are benign. They can be found anywhere in the central nervous system but are most commonly seen in the parasagittal, convexity and turbeculum sellae areas. There may be genetic mutations involved in the development of a<unk> , some of the genes involved includes NF2, MEG3, NDRG2, and SMARCE1. Multiple endocrine neoplasia 1, cowden syndrome, werner syndrome and neurofibromatosis 2 are some of the conditions that may be associated with<unk> . On microscopic pathology, some of the characteristic findings of a<unk>  include mitotic figures, necrosis, interdigitating processes, and brain invasion. Most<unk> s are positive for vimentin and negative for cytokeratin.
Meningioma pathophysiology
Glioma pathophysiology
Glioblastoma multiforme pathophysiology
Astrocytoma pathophysiology
Schwannoma pathophysiology
Lymphangioma pathophysiology
Ameloblastoma pathophysiology
Gliomatosis cerebri pathophysiology