The incidence of<unk> 's<unk>  has been ascertained from population studies in Norway and the United States and is similar at 6 to 7.1:100,000. Prevalence estimates for Northern Europe have ranged from 27–48 per 100,000.<unk> 's<unk>  tends to present initially in the teens and twenties, with another peak incidence in the fifties to seventies, although the<unk>  can occur at any age.<unk> 's<unk>  affects between 400,000 and 600,000 people in North America.<unk> 's<unk>  has a bimodal distribution in incidence as a function of age. There is no association with gender, social class or occupation.
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