<unk>  is an autosomal dominant thrombophilia, which leads to an increased risk of thromboembolic events. Protein S is a vitamin K-dependent glycoprotein and plays a role in anticoagulation. It is mainly a cofactor to the activated protein C (APC), which inactivates coagulation factors Va and VIIIa and thereby controlling the coagulation cascade.
Protein S deficiency
Protein C deficiency
Factor XIII deficiency
Antithrombin III deficiency
Factor I Deficiency
Activated protein C resistance
Factor V Leiden
Congenital protein C or S deficiency