<unk>  (also known as cerebral gigantism) is a rare genetic disorder characterized by excessive physical growth during the first 2 to 3 years of life. The disorder may be accompanied by mild mental retardation, delayed motor, cognitive, and social development, hypotonia (low muscle tone), and speech impairments. Children with<unk>  tend to be large at birth and are often taller, heavier, and have larger heads (macrocrania) than is normal for their age. Symptoms of the disorder, which vary among individuals, include a disportionately large and long head with a slightly protrusive forehead, large hands and feet, hypertelorism (an abnormally increased distance between the eyes), and downslanting eyes. Clumsiness, an awkward gait, and unusual aggressiveness or irritability may also occur. Although most cases of<unk>  occur sporadically, familial cases have also been reported.
Sotos syndrome
Clark-Baraitser syndrome
Patau syndrome
Weinstein Kliman Scully syndrome
Grange syndrome
De Grouchy Syndrome
Pierson syndrome
Mosse syndrome