The exact pathogenesis of<unk>  connective tissue disorder (UCTD) is not fully understood. It is understood that UCTD is the result of an autoimmune process and occurs in phases: Initial phase: which is asymptomatic and is characterized by absence of auto-antibodies and second phase which is characterized by the presence of auto-antibodies. The second phase is usually triggered by the environmental factors, such as infection. Auto-antibodies appear before the symptoms of the disease.The time between the two is variable. Autoantibodies usually seen in UCTD with positive correlation are antibodies against C1q ,Anti heat shock protein (hsp)-65, Anti hsp 60. The clinical picture involves the overlap of symptoms of other rheumatological disease but not completing the criteria of their diagnosis. More studies are needed to find the pathogenesis of UCTD.
Undifferentiated connective tissue disease pathophysiology
Mixed connective tissue disease pathophysiology
Fibromuscular dysplasia pathophysiology
Polymyalgia rheumatica pathophysiology
Buerger's disease pathophysiology
Scleroderma pathophysiology
Adrenoleukodystrophy pathophysiology
Autoimmune polyendocrine syndrome pathophysiology