<unk>  foramen ovale has been associated with<unk>  headaches, particularly those with an aura. However,<unk>  foramen ovale's role as a causative factor for<unk>  headaches is still not clear. The beneficial effect of<unk>  foramen ovale closure in<unk> s with<unk>  is controversial. Some smaller studies have shown some benefits of these closure, however, the large randomized double blinded 'MIST' trial failed to show any difference in cessation of<unk> s, between the percutaneous and the sham group.
Patent foramen ovale and migraine
Patent foramen ovale and decompression sickness
Patent foramen ovale and stroke
Unstable angina / non ST elevation myocardial infarction and diabetes mellitus
Congestive heart failure and obstructive sleep apnea
Asthma and gastroesophageal reflux
Cardiac disease in pregnancy and valvular heart disease
Cardiac disease in pregnancy and pulmonary hypertension