<unk>  is an anti rheumatic that is FDA approved for the treatment of adult patients with moderately to severely active rheumatoid arthritis. There is a Black Box Warning for this drug as shown here.  Common adverse reactions include anemia, hepatic steatosis, pruritis, tendonitis, pyrexia.
Tofacitinib
Ocrelizumab
Belatacept
Etanercept
Nebacumab
Efalizumab
Ibalizumab
Sarilumab