<unk> <unk>  is a strategy to overcome the problems of lack of tumor selectivity. An antibody designed/developed against a tumor antigen is linked to an<unk>  and injected to the blood, resulting in selective binding of the<unk>  in the tumor. When the discrimination between tumor and normal tissue<unk>  levels is sufficient, a<unk>  is administrated into the blood circultion, which is converted to an active cytotoxic drug by the<unk> , only within the tumor. Selectivity is achieved by the tumor specificity of the antibody and by delaying<unk>  administration until there is a large differential between tumor and normal tissue<unk>  levels.<unk>  has shown antitumor activity in animal tumor models of human choriocarcinoma and colonic and breast carcinoma.
Antibody-Directed Enzyme Prodrug Therapy
Boron Neutron Capture Therapy
Liver transplantation immune therapy
Bioartificial liver device
Monoclonal antibody therapy
Targeted therapy
Cryoglobulinemia medical therapy
Glucose-6-phosphate dehydrogenase deficiency surgery