Cystic fibrosis may be classified according to CFTR protein function abnormality into 6 classes and includes lack of production (class 1), failure to reach the site of action due to misfolding (class 2), defects in gating (class 3), reduced ion conductance (class 4), abnormally low channel numbers (class 5), and decreased half-life (class 6). Cystic fibrosis classes 1,2 and 3 are the most commonly associated with pancreatic insufficiency.
Cystic fibrosis classification
Cystic fibrosis laboratory findings
Cystic fibrosis laboratory tests
ACG guidelines classification scheme
Cyanosis classification
Silicosis classification
Alpha 1-antitrypsin deficiency epidemiology and demographics
Cystic fibrosis chest x ray