Proliferating Cell Nuclear Antigen, commonly known as<unk> , is a protein that acts as a processivity factor for DNA polymerase delta in eukaryotic cells.  It achieves this processivity by encircling the DNA, thus creating a topological link to the genome.  It is an example of a DNA clamp.
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
PCNA
APC 
MoCA
BRAF
TP53 
P53 
AKT
SMAS