Aspiration of anaerobic bacteria is the inciting event for the development of lung abscess. Once the aspirate is localized it results in pneumonitis. Inflammatory mediators are released, resulting in the formation of colliquative necrosis. The right side lung is more commonly affected than the left. On gross morphology, the lesions are well circumscribed filled with necrotic debris and do not demonstrate well-defined borders with the surrounding lung parenchyma. Microscopic examination demonstrates neutrophilic granulocytes with dilated blood vessels and inflammatory edema.
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Lung abscess pathophysiology
Lung abscess classification
Aspergillosis diagnostic criteria
Lung abscess laboratory findings
Pleural empyema classification
Farmer's lung differential diagnosis
Mediastinitis diagnostic criteria
Bronchitis pathophysiology