Except in newborns,<unk>  infection is only characteristically clinically relevant in immunocompromised individuals, particularly AIDS (Acquired Immunodeficiency Syndrome) patients (CD4 <50-100) and transplant patients.
Approximately 40% of the U.S. have been infected.
Transmission is through secretions, either via sexual contact, mother-infant transmission, or prolonged close personal contact.<unk>  is a member of the herpes family, and once a patient is infected, the virus persists and can become reactivated under immunocompromising circumstances. Sites of latency include monocytes and PMNs (polymorphonuclear leukocytes).
Approximately 40% of the U.S. have been infected.
Transmission is through secretions, either via sexual contact, mother-infant transmission, or prolonged close personal contact.
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