<unk><unk><unk><unk>  (SIBO) was first discovered by Barber and Hummel in 1939. There is no established system for the classification of<unk><unk><unk><unk>  (SIBO).The pathogenesis of<unk><unk><unk><unk>  (SIBO) is characterized by an increased microbial load in the<unk>  intestine. Disruption of protective homeostatic mechanisms can increase the risk of SIBO.<unk>  colonization causes an inflammatory response in the<unk>  mucosa. Damage to the<unk>  mucosa leads to malabsorption of bile acids, carbohydrates, proteins and vitamins resulting in symptoms of diarrhea and weight loss. On gross pathology, mucosal edema, loss of normal vascular pattern, patchy erythema, friability and ulceration of the<unk><unk>  wall is associated with<unk><unk><unk><unk>  (SIBO). On microscopic histopathological analysis<unk>  intestine and colon are normal in most patients with SIBO. Findings include blunting of the<unk>  villi, thinning of the mucosa and crypts, increased intraepithelial lymphocytes.<unk><unk><unk><unk>  (SIBO) must be differentiated from other diseases that cause chronic diarrhea.<unk><unk><unk><unk>  is more commonly observed among elderly patients.<unk><unk><unk><unk>  (SIBO) affects men and women equally.There is no racial predilection for<unk><unk><unk><unk>  (SIBO). Early clinical features include bloating, flatulence, abdominal pain. If left untreated, patients with<unk><unk><unk><unk>  (SIBO) may progress to develop diarrhea, dyspepsia and weight loss. Prognosis is generally good and associated with frequent relapses and symptom-free periods. The diagnosis of<unk><unk><unk><unk>  (SIBO) is made when at least one of the following diagnostic criteria are met: a positive carbohydrate breath test or<unk>  concentration of >103 units/mL in a jejunal aspirate culture. Physical examination may be remarkable for distended abdomen with positive succussion splash as a result of distended bowel loops and peripheral edema due to malabsorption.<unk><unk><unk>  obstruction(SIBO) may also be diagnosed using breath tests. The mainstay of therapy for<unk><unk><unk><unk>  (SIBO) is antibiotic therapy. Surgical approach can only be performed for patients with strictures, fistulae, and diverticula or any other structural abnormality resulting in obstruction and resultant<unk><unk> . Effective measures for the prevention of<unk>  bowel<unk><unk>  syndrome include avoiding medications like narcotics and benzodiazepines that decrease<unk>  motility and avoid achlorhydria in high-risk patients. Consider antibiotic prophylaxis for patients with four or more episodes of recurrent<unk>  bowel<unk><unk>  syndrome within one year.
Small intestinal bacterial overgrowth syndrome
Pseudomembranous enterocolitis
Seckel syndrome
Meckel syndrome
Necrotizing enterocolitis
Necrotising enterocolitis
Schnitzler syndrome
Tropical sprue