<unk>  was first discovered by Lowenstein, in 1906. The index case of<unk>  was found in a patient suffering from severe post-traumatic lymphedema of arm.<unk>  is a rare malignant tumor which occurs in long-standing cases of primary or secondary lymphedema. It involves either the upper or lower lymphedemateous extremities but is most common in upper extremities.<unk>  must be differentiated from other diseases that cause swelling of limb.<unk>  is a rare entity and 300 cases of<unk>  after breast cancer have been reported worldwide. Common risk factors that may lead to the development of<unk>  include lymphatic blockage, radiotherapy, mastectomy, cardiovascular diseases, and hypertension. The sarcoma first appears as a bruise mark, a purplish discoloration or a tender skin nodule in the extremity, typically on the anterior surface. Findings on biopsy and ultrastructural histologic studies suggestive of<unk>  include proliferating vascular channels, hyperchromatism, pleomorphism, mitoses, pinocytosis, intercellular junctions, cytoplasmic intermediate filaments, Weibel-Palade bodies, and erythrophagocytosis. Amputation of the affected limb is the most common approach to the treatment of<unk> .
Lymphangiosarcoma
Angiosarcoma
Angiokeratoma
Liposarcoma
Lymphangioma
Pyogenic granuloma
Sarcoma
Hemangioma