<unk>  is a common sexually transmitted disease (STD) caused by the gram negative bacterium<unk>  trachomatis.<unk>  is the most frequently reported bacterial sexually transmitted<unk>  in the United States and is a major<unk> s cause of human eye and genital disease.<unk>  must be differentiated from other genital tract<unk> s, such as gonorrhea<unk> , bacterial vaginosis, vaginal candidiasis,<unk>  with Trichomonas vaginalis, and mycoplasma<unk> . Almost two-thirds of new<unk> s occur among youth aged 15-24 years. Females are more commonly affected with<unk>  than males. The female to male ratio is approximately 1.52 to 1. Common risk factors in the development of<unk>  include unprotected sexual activity, multiple sexual partners, age, men who have sex with men, and low socioeconomic status. According to the 2015 Sexually Transmitted Diseases Treatment Guidelines released by the CDC, screening for<unk>  is recommended for sexually active individuals under 25 years of age, women over 25 who are at increased risk, all pregnant women under 25 years, pregnant women over 25 who are at increased risk, men who have sex with men, and individuals with HIV. If left untreated,<unk>  can cause pelvic inflammatory disease in females and epididymitis and orchitis in males. Common complications of<unk>  among women include cervicitis, infertility, ectopic pregnancy, and chronic pelvic pain.  Complications of<unk>  in men include proctitis, epididymitis, and sterility. Prognosis of<unk>  is generally good with adequate treatment. Common symptoms of<unk>  among women include abnormal vaginal bleeding or discharge, abdominal pain, painful sexual intercourse, painful urination, and urinary urgency. Symptoms of<unk>  among men include penile discharge and pruritus, testicular pain or swelling, and pain during urination. Physical examination of women with<unk>  is usually remarkable for a cloudy, yellow mucoid cervical discharge; a friable appearance of the cervix; and cervical motion tenderness. Common physical examination findings of<unk>  among men include a clear or white urethral discharge, testicular tenderness, and testicular swelling. Transvaginal ultrasound, pelvic MRI, and laboratory nucleic acid amplification tests (NAAT) may be used in the diagnosis of<unk> . The mainstay of therapy for<unk>  is antimicrobial therapy with doxycycline. Effective measures for the primary prevention of<unk>  include practicing abstinence, avoiding high-risk sexual behaviors such as unprotected sex or multiple sexual partners, and using latex condoms. Secondary prevention of<unk>  includes early detection, treatment of sexual partners, and treatment of other sexually transmitted<unk> s (such as gonorrhea).
Chlamydia infection
Bacterial vaginosis
Cervical dysplasia
Leukorrhea
Atrophic vaginitis
Endometritis
Cervical polyp
Miscarriage