<unk>  is a number of disorders which are the most severe form of congenital chondrodysplasia (malformation of bones and cartilage). These conditions are characterized by a small body, short limbs, and other skeletal abnormalities. As a result of their serious health problems, infants with<unk>  are usually born prematurely, are stillborn, or die shortly after birth from respiratory failure. Some infants, however, have lived for a while with intensive medical support.
Researchers have described at least two forms of<unk> , designated as type 1B and type 2. These types are distinguished by their signs and symptoms, inheritance pattern, and genetic cause. Other types of<unk>  may exist, but they have not been characterized or their cause is unknown.
Achondrogenesis
Oogenesis
Tooth fusion
Lipogenesis
Limb development
Kidney development
Labial fusion
Neurulation