Statin induced myopathy has a complex poorly understood multifactorial pathophysiology. It is postulated that statin induced myopathy is caused by apoptosis of the skeletal muscle cells due to disrupted intracellular calcium signaling and mitochondrial dysfunction secondary to depletion of mevalonate metabolism products, particularly coenzyme Q10.
Statin induced myopathy pathophysiology
Statin induced myopathy risk factors
Statin induced myopathy epidemiology and demographics
Statin induced myopathy medical therapy
Statin induced myopathy differential diagnosis
Cryoglobulinemia pathophysiology
Cardiac amyloidosis other diagnostic studies
Primary amyloidosis pathophysiology