Human<unk>  is usually transmitted via the sexual route to the human host. HPV life cycle is linked to epithelial differentiation and maturation of host keratinocytes, with transcription of specific gene products at every level. The pathogenesis of HPV infection causing cancer is mainly linked to high risk types of HPV (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 68). E6 and E7 protein products of HPV interact with two important cell cycle regulatory protiens, P53 and Rb proteins of host cell, causing unchecked cellular replication accumulating mutations leading to cancer.
Human papillomavirus pathophysiology
Vaginal cancer pathophysiology
Cervical dysplasia pathophysiology
Cervical cancer pathophysiology
Human papillomavirus epidemiology and demographics
Genital candidiasis pathophysiology
Chlamydia infection pathophysiology
Endometrial cancer pathophysiology