Sacrococcygeal teratoma originates from the pluripotent cells in primitive knot or Hensen's node, which is the primary organizer of embryonic development, located on the anterior surface of the sacrum or coccyx by the 2nd or 3rd gestational week. Development of sacrococcygeal teratoma is associated with gain of chromosomes 1q32-qter regions and loss of the 6q24-qter and 18q21-qter regions. The pathophysiology of sacrococcygeal teratoma depends on the histological subtype.
Sacrococcygeal teratoma pathophysiology
Germinoma pathophysiology
Sacrococcygeal teratoma epidemiology and demographics
Seminoma pathophysiology
Teratoma pathophysiology
Sacrococcygeal teratoma laboratory findings
Myxoma pathophysiology
Hamartoma pathophysiology