<unk>  <unk>  is a highly reliable carcinogen, mutagen, and teratogen. <unk>  is an alkylating agent, and exhibits its toxicity by transferring its methyl group to nucleobases in nucleic acids, which can lead to AT:GC transition mutations.<unk>  is the traditional precursor in the synthesis of diazomethane. However, since it is unstable at temperatures beyond 20 °C and shock-sensitive to a degree, for this purpose it has become obsolete and replaced by other (N-methyl)nitrosamides. Most chemical supply houses have stopped carrying it.
Acute exposure to<unk>  in humans can result in skin and eye irritation, headache, nausea, and vomiting. <unk>  is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity in experimental animals (IARC 1972, 1978, 1987).  Various cancers induced in animal models include: squamous cell carcinomas of the forestomach, sarcomas and gliomas of the brain, adenocarcinomas of the pancreas, leukemia, and lymphomas.  However, the actual potential for human exposure is quite limited, as the chemical is not produced or used in large quantities <unk>  is teratogenic and embryotoxic, resulting in craniofacial (cleft palate) and skeletal defects, increased fetal resorption, and fetal growth retardation.  Exposure to<unk>  during pre-implantation, post-implantation, organogenesis, or by paternal exposure can result in these effects.
N-Nitroso-N-methylurea
N-Nitroso-N-Methylurea
8-Hyydroxyquinoline
Diiodohydroxyquinoline
4-Aminobenzoic acid
4-Nitroquinoline 1-oxide
Nitrazine
Monobenzone