<unk>  (INN), also known as diacetylrhein, is a slow-acting medicine of the class anthraquinone used to treat joint diseases such as osteoarthritis (swelling and pain in the joints). It works by inhibiting interleukin-1 beta. A 2005 Cochrane review found<unk>  to be slightly, but significantly, more effective than placebo in improving pain and slowing the progress of osteoarthritis in the hip and knee.<unk> -containing medicines are currently authorized in the following European Union (EU) Member States: Austria, Czech Republic, France, Greece, Italy, Portugal, Slovakia and Spain.
Diacerein
Ioglicic acid
Bitolterol
Piceatannol
Lanatoside C
Pyritinol
Gedocarnil
Clioquinol