The incidence of<unk><unk>  is hard to determine, as many sufferers of the milder forms of the disorder are asymptomatic and their condition never comes to medical attention.Around 90% of those with this disorder are thought to fall into the asymptomatic population.It is estimated that its incidence is between 3 and 5 per 10,000 in the USA.Some subtypes of<unk><unk>  are significantly more prevalent in regions where malaria is endemic.
Being an almost wholly autosomal dominant disorder, there is no predilection towards either sex in<unk><unk> .
The most important exception to this rule of autosomal dominant inheritance is for a subtype of<unk><unk>  called<unk>  pyropoikilocytosis (HPP). This condition is autosomal recessive.
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