<unk> proteins (an acronym derived from "soluble N-ethylmaleimide sensitive fusion protein (NSF) attachment receptor") are a large protein superfamily consisting of more than 60 members in yeast and mammalian cells.
The primary role of<unk> proteins is to mediate fusion of cellular transport vesicles with the cell membrane or with a target compartment (such as a lysosome).<unk>  can be divided into two categories: vesicle or v-SNAREs , which are incorporated into the membranes of transport vesicles during budding, and target or t-SNAREs, which are located in the membranes of target compartments.
Recent classification however takes account of the structural features of the<unk> proteins and divides them into R-SNAREs and Q-SNAREs.
The best-studied<unk>  are those that mediate docking of synaptic vesicles with the presynaptic membrane. These<unk>  are the targets of the bacterial neurotoxins responsible for botulism and tetanus.
SNARE 
TORCH complex
Rho GTPase
AMPA receptor
Cadherin
Calcium channel
SMAS
Small GTPase