<unk>  arise from remnants of ameloblast or dental lamina, dentigerous cysts, or basal layer of oral mucosa. There is evidence that suppression of matrix metalloproteinase-2 may inhibit the local invasiveness of<unk> . On gross pathology, the characteristic findings of<unk>  may include solid and cystic, multicystic and intraosseous or extraosseous, or rarely unicystic. On microscopic histopathological analysis, stellate reticulum, giant cells, subepithelial hyalinization, and columnar basal cells in palisading arrangement with vacuolated cytoplasm are characteristic findings of<unk> . The exact<unk>  of<unk>  is not fully understood. It is thought that<unk>  is the result of either suppression of matrix metalloproteinase-2 that may inhibit the local invasiveness of<unk> , or there is also some research suggesting that α5β1 integrin may participate in the local invasiveness of<unk> . Genes involved in the pathogenesis of<unk>  include BRAF V600E.
Ameloblastoma pathophysiology
Medulloblastoma pathophysiology
Glioma pathophysiology
Astrocytoma pathophysiology
Glioblastoma multiforme pathophysiology
Meningioma pathophysiology
Schwannoma pathophysiology
Oligodendroglioma pathophysiology