<unk>  (also known as<unk>  antibody,<unk> , or<unk>  inhibitors) is a medical phenomenon where autoantibodies bind to phospholipids and proteins associated with the cell membrane. Since interactions between the cell membrane and clotting factors are necessary for proper functioning of the coagulation cascade, the<unk>  can interfere with blood clotting as well as in-vitro tests of clotting function. Paradoxically,<unk> s are also risk factors for thrombosis.
The name<unk> " is a misnomer.  Most patients with a<unk>  do not actually have<unk>  erythematosus, and only a small proportion will proceed to develop this disease (which causes joint pains, skin problems and renal failure, amongst other complications).  Patients with<unk>  erythematosus are more likely to develop a<unk>  than the general population.
Conceptually,<unk> s overlap with the antiphospholipid antibody syndrome.<unk> s can be understood as the tendency of antiphospholipid antibodies to prolong the clotting times, especially in phospholipid rich clotting testing such as the dilute Russell's viper venom time.
Often, the<unk>  is diagnosed on asymptomatic patients by a routine blood testing prior to surgery. Patients with a<unk>  are prone to thrombosis, excess bleeding, and habitual abortion (repeated miscarriages).
Lupus anticoagulant
Antihemophilic Factor 
Antihemophilic factor
Antihemophilic factor 
Factor V Leiden
Antithrombin III
Thrombus precursor protein 
Fibrin degradation product