<unk>  is a selective serotonin 5-HT3 antagonist that is FDA approved for the {{{indicationType}}} of severe diarrhea-predominant irritable bowel syndrome (IBS). There is a Black Box Warning for this drug as shown here.  Common adverse reactions include constipation, abdominal pain, nausea, and gastrointestinal discomfort and pain.
Alosetron
Lerisetron
Tropisetron
Ramosetron
Granisetron 
Cilansetron
Palonosetron
Dolastetron 