The exact pathogenesis of uveitis is not fully understood. It is thought that uveitis is mediated by a genetic predisposition and an acquired cross immunity to infectious agents, or cross immunity to self-antigens due to underlying autoimmune diseases. It is estimated that 35% to 50% of cases of uveitis are idiopathic. Development of uveitis is hypothesized to be the result of a genetic predisposition for acquiring the disease; contributions of several human leukocyte antigen (HLA) alleles are most commonly implicated.
Uveitis pathophysiology
Retinitis pathophysiology
Lymphangitis pathophysiology
Aortitis pathophysiology
Buerger's disease pathophysiology
Microscopic polyangiitis risk factors
Uveitis causes
Uveitis risk factors