An estimated 20 million HEV infections and 3.3 million acute cases occur annually worldwide with an estimated 56 600 deaths. HEV displays different epidemiological and clinical characteristics between developing and developed countries. In the United States, studies show an incidence of 700 cases per 100,000 of the overall population, and a seroprevalence of 21,000 per 100,000 persons.  Clinical manifestations of hepatitis E are more frequent among adult patients.  When compared to men, women have a smaller rate of hepatitis E (20,4% vs 21,6%). Pregnant women are more prone to develop severe cases of the disease.  In developed countries, the disease often occurs as small outbreaks, commonly transmitted by ingestion of undercooked meat. In developing countries, the disease may occur as an epidemic, or as outbreaks, and is often associated with genotypes 1 and 2, which are transmitted through the ingestion of contaminated water.
Hepatitis E epidemiology and demographics
Hepatitis B epidemiology and demographics
Hepatitis C epidemiology and demographics
Alcoholic hepatitis epidemiology and demographics
Autoimmune hepatitis epidemiology and demographics
Hepatitis B diagnostic criteria
Malaria epidemiology and demographics
Hepatitis C classification