<unk>  is cancer that begins in the cells of the<unk> . Approximately 25-30% of all oral cavity cancers begin in the<unk> . If cancer begins in the proximal two-thirds of the<unk>  it is described as oral cancer and if it begins on the distal third of the<unk>  it is described as throat cancer. Squamous cell carcinoma of the<unk>  usually arises from the ventrolateral aspect of the mid and posterior<unk> , probably due to adjacent pooling of carcinogens. More than 90% of oral cavity cancers are squamous cell carcinomas. The majority of the other lesions are of minor salivary gland origin. Nonsquamous cell cancers comprise fewer than 3% of all lingual malignancies. Genes involved in the pathogenesis of<unk>  include TP53, c-myc, and erb-b1. On gross pathology, exophytic, ulcerative, and infiltrative growth patterns are characteristic findings of<unk> .<unk>  must be differentiated from other diseases that cause malignant lesions of the oral cavity and from few non-neoplastic lesions of the oral cavity, such as lymphoma, adenoid cystic carcinoma, adenocarcinoma, mucoepidermoid carcinoma, rhabdomyosarcoma, liposarcoma, infections at the floor of mouth and mandible, and normal adenoid tissue for lesions at the base of<unk> . In 2009, the incidence of<unk>  was estimated to be 10,530 cases per 100,000 individuals in the United States. Males are more commonly affected by<unk>  than females. The incidence of<unk>  increases with age. The most potent risk factor in the development of oral cancer is alcohol intake, tobacco use and human papillomavirus transmitted through sexual contact. Head and neck MRI scan is diagnostic of<unk> . The predominant therapy for<unk>  is surgical resection. Adjunctive chemotherapy, radiation, chemoradiation, or brachytherapy may be required.
Tongue cancer
Epiglottitis
Blepharitis
Laryngeal cancer
Adenoiditis
Ear cancer
Oropharyngeal cancer
Geographic tongue