<unk>  poisoning is a medical condition, also known as saturnism, plumbism, or painter's colic caused by increased  blood<unk>  levels.<unk>  may cause irreversible neurological damage as well as renal disease, cardiovascular effects, and reproductive toxicity.
Humans have been mining and using this heavy metal for thousands of years, poisoning themselves in the process due to accumulation and exposure.  These dangers have long been known, though the modern understanding of their full extent and the small amount of<unk>  necessary to produce them is relatively recent; blood<unk>  levels once considered safe are now considered hazardous, with no known threshold.  Reducing these hazards requires both individual actions and public policy regulations.
Lead poisoning-1
Gold poisoning
Mercury poisoning
Coastal leucothoe poisoning
Arsenic poisoning
Organophosphate poisoning
Strychnine poisoning
Cyanide poisoning