It is understood that pheochromocytoma is mediated by excessive secretion of catecholamines and subsequent stimulation of adrenergic receptors. It arises from the chromaffin cells of the adrenal medulla and sympathetic ganglia. The pathophysiology of pheochromocytoma does not depend on the histological subtype. Malignant and benign pheochromocytomas share the same biochemical and histological features. It may be sporadic or familial. All of these forms have genetic origin depending on a large number of genes, for example, VHL, SDH, NF1, RET genes. It is associated with conditions like MEN 2A syndrome, MEN 2B syndrome, VHL disease, and NF1.
Pheochromocytoma pathophysiology
Pheochromocytoma laboratory findings
Pheochromocytoma classification
Pheochromocytoma risk factors
Primary hyperaldosteronism MRI Findings
Acromegaly pathophysiology
Pheochromocytoma medical therapy
Primary hyperaldosteronism pathophysiology