While cryptococcus and candida infections occur worldwide, other<unk>  infections tend to cluster in specific geographical regions. There is an increasing trend of<unk><unk> . This has been attributed  to enlarging population of high-risk immunosuppressed patients, more successful pharmacological immunosuppression and chemotherapies, increase in numbers of patients living with human immunodeficiency virus (HIV) infection and the acquired immunodeficiency syndrome (AIDS), migration of susceptible persons into hyperendemic areas and aging of the population. Cryptococcal<unk>  occurs worldwide but it is highly prevalent in southeast Asia and southern and east Africa where the prevalence of HIV is high. The incidence of cryptococcal<unk>  is almost the same as in meningococcal<unk>  with an incidence of one case per 100,000 persons.
Prior to the introduction of highly active antiretroviral therapy (HAART) in the United States, yearly incidence rate of cryptococcal<unk>  was on ascendancy with incidence of  6600 cases per 100,000 persons with AIDS  The incidence has decreased with the advent of HAART  although cases are still reported. The worldwide incidence of cryptococcal<unk>  is pegged at 1,000,000 annually according to an estimate by Centers for Disease Control and Prevention CDC in 2009 with approximately half of these resulting in death. The prevalence of<unk><unk>  does not vary with gender. Non-Caucasian race have a higher prediclection to developing<unk><unk>  especially coccidioidal<unk>  The prevalence of<unk><unk>  does not vary with age. The major factor accounting for age predilection has to do with the clinical state of the patient and the immune response. For example candida<unk>  may occur in older children and in adults with neutropenia, often presenting with brain abscesses rather than<unk> . Children with certain conditions have higher incidence of<unk><unk>  example myeloperoxidase deficiency, chronic granulomatous disease of childhood and chronic mucocutaneous candidiasis.
Fungal meningitis epidemiology and demographics
Bacterial meningitis epidemiology and demographics
Japanese encephalitis epidemiology and demographics
Neoplastic meningitis epidemiology and demographics
St. Louis encephalitis epidemiology and demographics
Meningococcemia epidemiology and demographics
Viral encephalitis Epidemiology and Demographics
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