<unk> s are naturally produced eicosanoid lipid mediators, which may be responsible for a number of the effects of asthma and allergies.<unk> s use both autocrine signalling and paracrine signalling to regulate the body's response.<unk> s are produced in the body from arachidonic acid by the enzyme 5-lipoxygenase. Their production by the body is part of a complex response that usually includes the production of histamine.
Leukotriene
Thromboxane
Nitric oxide
Prostaglandin F2alpha
Prostaglandin
Eicosanoid
Superoxide
Nitrosamine