<unk>  arises from the cartilage cells (chondrocytes), which are normally involved in the mechanical support of the bone. The pathogenesis of<unk>  consists of abnormal outgrowth of bone and cartilage, associated with the aberrant development of the growth plate. Genes involved in the pathogenesis of<unk>  include EXT1 and EXT2 genes.<unk>  is associated with a number of syndromes that include Langer-Giedion syndrome, Potocki-Shaffer syndrome, and metachondromatosis syndrome. On gross pathology,<unk> s have a "mushroom-like shape", the tumor size ranges from 1 to 2 cm, and  they are normally located in the metaphysial region of the affected bone. On microscopic histopathological analysis,<unk>  shows cartilage cells growing in columns with a lobular arrangement.
Osteochondroma pathophysiology
Osteoma pathophysiology
Osteosarcoma pathophysiology
Osteochondroma epidemiology and demographics
Osteomyelitis pathophysiology
Osteoarthritis pathophysiology
Osteochondroma risk factors
Osteochondroma staging