A<unk> <unk> , for short) is any enzyme that catalyzes the hydrolytic cleavage of phosphodiester linkages in the DNA backbone.<unk> s are thus one type of nuclease.  A wide variety of<unk> s are known, which differ in their substrate specificities, chemical mechanisms, and biological functions.
Deoxyribonuclease
Ligase
Restriction enzyme
DNA glycosylase
DNA polymerase
Oxidoreductase
RNA polymerase
Hydrolase