In cellular pathology,<unk>  (also called fatty change) is the process describing the abnormal retention of lipids within a cell. It reflects an impairment of the normal processes of synthesis and breakdown of triglyceride fat. Excess lipid accumulates in vesicles that displace the cytoplasm. When the vesicles are large enough to distort the nucleus, the condition is known as macrovesicular<unk> , otherwise the condition is known as microvesicular<unk> . Whilst not particularly detrimental to the cell in mild cases, large accumulations can disrupt cell constituents, and in severe cases the cell may even burst.
The risk factors associated with<unk>  are varied, and include diabetes mellitus, protein malnutrition, hypertension cell toxins, obesity, and anoxia. As the liver is the primary organ of lipid metabolism it is most often associated with<unk> , however it may occur in any organ, commonly the kidneys, heart, and muscle.
Steatosis
Degranulation
Hyperpigmentation
Xerosis
Bauxite fibrosis
Siderosis
Porokeratosis
Transistasis