<unk><unk> ’s<unk>  is an genetic coagulation disorder with resultant abnormality in platelet adhesion and aggregation.<unk>  <unk>  is the most common genetic coagulation disorder described in humans.  It affects up to 1% of the population, although most cases are mild. Symptomatic<unk>  is much rare, ~1 in 10000.<unk>  arises from a qualitative or quantitative deficiency of<unk><unk>  factor (vWF), a large glycoprotein protein that is required for platelets to bind to collagen.  vWF is therefore important in primary hemostasis.  When the<unk>  comes to medical attention, it usually presents in the typical manner for platelet disorders mucosal bleeding and easy bruising. The<unk>  is usually inherited in an autosomal dominant manner, although there are recessive forms as well, and it can also be acquired secondary to another<unk> .
Von Willebrand disease
Factor V Leiden
Hemophilia
Grey platelet syndrome
Bernard-Soulier syndrome
Familial dysfibrinogenemia
Hemophilia C
Hemophilia B