SIRS can be diagnosed when two or more of the following are present:
Heart rate > 90 beats per minute
Temperature < 36 (96.8 °F) or > 38 °C (100.4 °F)
Tachypnea > 20 breaths per minute or, on blood gas, a PaCO2 < 32 mm Hg
White blood cell count < 4000 cells/mm³ or > 12000 cells/mm³ (< 4 x 109 or > 12 x 109 cells/L), or > 10% band forms (immature white blood cells / bandemia).
SIRS can be seen in non infectious conditions like pancreatitis and myocardial infarction.
Heart rate > 90 beats per minute
Temperature < 36 (96.8 °F) or > 38 °C (100.4 °F)
Tachypnea > 20 breaths per minute or, on blood gas, a PaCO2 < 32 mm Hg
White blood cell count < 4000 cells/mm³ or > 12000 cells/mm³ (< 4 x 109 or > 12 x 109 cells/L), or > 10% band forms (immature white blood cells / bandemia).
SIRS + Source of infection
Sepsis + organ dysfunction
Organ damage can present as decreased urine output, acute kidney injury, and elevated liver function tests.
Severe sepsis + persistent hypotension after adequate fluid challenge.
Progressive multiple organ failure secondary to severe sepsis.
MICU Intern's survival guide sepsis
Cardiogenic shock diagnostic criteria
Sepsis diagnostic criteria
Cardiogenic shock echocardiography or ultrasound
MICU intern's survival guide vasopressors
Anoxic brain injury physical examination
Tumor lysis syndrome diagnostic criteria
Toxic shock syndrome classification