Initial evaluation of a patient for a suspected functional platelet disorder should include a complete blood count and examination of the peripheral blood smear. The red blood cell count is usually normal. Some patients with Glanzmann's<unk>  may have reduced count of red blood cell, because of coexisting iron deficiency or bleeding. The platelet count in Glanzmann's<unk>  is mostly on the lower end of normal. The activated partial thromboplastin time (PTT) and prothrombin time (PT) are in this disease commonly normal. Platelet aggregation assays which is panel of assays measuring platelet aggregation and activation in vitro using like ADP, arachidonic acid, collagen, epinephrine, thrombin, and ristocetin. There are several newer technologies in current clinical use measuring various aspects of platelet function. The most widely tested is the PFA-100 device. It is used to distinguish between an aspirin-induced defect and more severe platelet dysfunction. Platelet aggregation failure in LTA with all agonists except ristocetin is diagnostic of Glanzmann's<unk> .  Laboratory<unk>  consistent with the diagnosis of Glanzmann's<unk>  include prolonged bleeding time (BT) and failure of platelets plugging to the collagen-based filter in the PFA-100 test.
Glanzmann's thrombasthenia laboratory findings
Heparin-induced thrombocytopenia laboratory findings
Von Willebrand disease laboratory findings
Disseminated intravascular coagulation laboratory findings
Thrombotic thrombocytopenic purpura risk factors
Antiphospholipid syndrome laboratory findings
Glanzmann's thrombasthenia physical examination
Glanzmann's thrombasthenia other diagnostic studies