<unk>  is a guanylate cyclase-C agonist that is FDA approved for the treatment of chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C). There is a Black Box Warning for this drug as shown here.  Common adverse reactions include diarrhea.
Plecanatide
Peginesatide
Eptifibatide
Defibrotide
Oprelvekin
Drotrecogin alfa
Iofendylate
Picloxydine