It seems portal vein thrombosis is caused by Virchow's triad which includes: Reduced portal blood flow, hypercoagulable state, and vascular endothelial injury. There are two mechanisms that contribute in loss of portal vein blood flow to liver, arterial rescue and venous rescue. It is a rapid process and takes a few days to start and 3-5 weeks to complete after portal vein obstruction. Collateral vessel joins to form cavernoma which connects the proximal and distal part of thrombosed portal vein. Finally, the portal vein becomes a fibrosed and thin cord. All these events leads to low systemic vascular resistance and high. These are the characterstic findings of hyperkinetic circulation.
Portal vein thrombosis pathophysiology
Deep vein thrombosis pathophysiology
Splenic vein thrombosis pathophysiology
Varicose veins pathophysiology
Splenic vein thrombosis risk factors
Portal vein thrombosis risk factors
Suppurative thrombophlebitis pathophysiology
Suppurative thrombophlebitis risk factors