'''Hemophilia A''' is a blood clotting disorder caused by a mutation of the factor VIII gene, leading to a deficiency in Factor VIII. It is the most common hemophilia. Inheritance is X-linked recessive; hence, males are affected while females are carriers or very rarely display a mild phenotype. 1 in 5,000 males are affected.
"Hemophilia B" is also a blood clotting disorder similar to<unk>  to the extent that these two diseases have been considered clinically indistinguishable.<unk>  inheritance is also  X-linked, however it is caused by the mutation of factor IX gene. The overall clinical severity of<unk>  in terms of equal amount of factor deficency is believed to be less severe than<unk> , besides the prevalence of the disease is also lower; 1 in 30,000 males.
There is also another type of bleeding disorder related to deficiency of factor XI known as<unk> , it is a rare autosomal disease with usually mild phenotype and is almost exclusively seen in Ashkenazi Jews hence the concentration of our<unk> age here is mostly directed towards<unk>  and B.
Hemophilia A
Hemophilia C
Hemophilia B
Factor V Leiden
Von Willebrand disease
Familial dysfibrinogenemia
Bernard-Soulier syndrome
Patau syndrome