The disease caused by EV-D68 infection is considered a rare entity. The true incidence and prevalence are not known, but a recent rise in reported cases has been observed. Although old data suggested predominance among children between the ages 4 to 5 years, new cases reveal adult preponderance. EV-D68 infection is more prevalent among males, with no variation by race or ethnicity. People with respiratory infections such as asthma, chronic obstructive pulmonary disease and atopy are also more prone to develop severe infection with EV-D68.
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