<unk>  refers to the increase in size of the prostate in middle-aged and elderly men. To be accurate, the process is one of<unk>  rather than hypertrophy, but the nomenclature is often interchangeable, even amongst urologists. It is characterized by<unk>  of prostatic stromal and epithelial cells, resulting in the formation of large, fairly discrete nodules in the periurethral region of the prostate. When sufficiently large, the nodules compress the urethral canal to cause partial, or sometimes virtually complete, obstruction of the urethra which interferes the normal flow of urine. It leads to symptoms of urinary hesitancy, frequent urination, increased risk of urinary tract infections and urinary retention. Although prostate specific antigen levels may be elevated in these patients, because of increased organ volume and inflammation due to urinary tract infections,<unk>  is not considered to be a premalignant lesion.
Benign prostatic hyperplasia
Chronic bacterial prostatitis
Neurogenic bladder
Urethral cancer
Prostatic intraepithelial neoplasia
Interstitial cystitis
Bladder cancer
Prostate cancer