<unk><unk><unk>  is a neurodegenerative disease of upper and lower motor neurons. It is diagnosed clinically along with supportive electrophysiological testing. However, there is no specific biological marker that correlates with the disease pathology. The clinical diagnosis is straightforward in the majority of the cases, but false positive and false negative cases can arise early in the disease process. It usually occurs when only upper motor neurons or lower motor neurons signs and symptoms are present. It might be difficult to exclude ALS with only LMN signs with other spinal muscular atrophies, poliomyelitis, and Kennedy disease, etc.
Amyotrophic lateral sclerosis differential diagnosis
Parkinson's disease differential diagnosis
Transverse myelitis differential diagnosis
Guillain-Barré syndrome differential diagnosis
Acute disseminated encephalomyelitis differential diagnosis
Viral encephalitis differential diagnosis
Encephalopathy differential diagnosis
Lightheadedness and vertigo differential diagnosis