<unk><unk>  (HCM) is the most common inherited heart disease. Prevalence rates have been reported between 1:500 (0.2%) and 1:3,000 (0.03%) because of variations in study designs and cohort characteristics including different age groups and ethnicity. According to the CARDIA (Coronary Artery Risk Development in Young Adults) cohort study that used standard echocardiography in 4,111 unrelated people 23 to 35 years of age, HCM prevalence is reported as 1 in 500 persons (0.2%). Nevertheless, lower prevalence has been reported in some European countries such as Germany (0.07%). Patients of all age groups may develop<unk><unk> . Prevalence increased with advancing age and showed a constant yearly rise but sudden death is more prevalent in young patients, particularly athletes. The case-fatality rate is  6 per 10,000 per year in young people without symptoms of<unk><unk>  but in syptomatic patients a case-fatality rate is 420 and 110 deaths per 10,000 per year in tertiary referral centers and general hospital clinics respectively.<unk><unk>  affects men and women equally. However, despite more frequent outflow obstruction, women with HCM are underrecognized and referred to centers later than men, often with more advanced heart failure. Greater awareness of HCM in women should lead to earlier diagnosis and treatment, with implications for improved quality of life. HCM is less prevalent in African Americans, but they are more pron to early presentation, developing heart failure, and sudden death is more prevalent due to less awareness and screening in this population.
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