<unk>  occurs due to the discontinuation or reduction of opioid use in individuals with heavy and prolonged opioid use or may be precipitated by the administration of an opioid antagonist in an individual with prolonged opioid use or by the administration of an opioid partial agonist in an individual that is currently using a full opioid agonist. Symptoms of withdrawal from opiates include, but are not limited to, depression, anxiety, irritability, leg cramps, abdominal cramps, nausea, vomiting, diarrhea, insomnia, pain, tremor, rhinorrhea, sweating, and cravings for the drug itself. Depending on the opioid's half-life, the symptoms of<unk>  usually resolve within 5 to 14 days, however, many patients require appropriate treatment. The DSM-V diagnostic criteria is used for the diagnosis of<unk> . The medications for treatment include methadone, clonidine, buprenorphine, and adjunctive drugs.
Opioid withdrawal
Opiate withdrawal
Cocaine withdrawal
Alcohol withdrawal
Opioid abuse and dependence
Opioid overdose
Cocaine dependence
Marijuana intoxication