<unk>  is one of the subtypes of familial amyloidosis, it is associated with four mutations include, Ile56Thr, Asp67His, Trp64Arg, and Phe57Ile. It is an extremely rare disease and it commonly affects individuals in their third to fourth decades of life. Manifestation of the disease are based on which organs are involved, and include GI symptoms, renal impairment, sicca syndrome, lymphadenopathy, splenomegaly, and petechiae or purpura. The diagnosis of<unk>  is based on the family history, histologic examination and amino acid sequencing. There is no treatment for<unk> ; the mainstay of therapy is supportive care. Organ transplant could be done as palliative treatment.
Lysozyme amyloid related amyloidosis
Gelsolin related amyloidosis
Transthyretin-related hereditary amyloidosis
Leucocyte cell-derived chemotaxin 2 related amyloidosis
Beta-2 microglobulin related amyloidosis
Secondary amyloidosis
Fibrinogen A alpha-chain associated amyloidosis
Primary amyloidosis pathophysiology