<unk>  is an autoimmune disease in which an individual's antibodies attack their own RBCs as well as their platelets.  Its overall pathology is therefore effectively a combination of the two autoimmune induced conditions: autoimmune hemolytic anemia and immune thrombocytopenic purpura. 
Autoimmune hemolytic anemia is a condition in which the red blood cells that normally carry oxygen and carbon dioxide are destroyed by an autoimmune process. Immune thrombocytopenic purpura is a condition in which the platelets in the blood are destroyed by an autoimmune process.  Platelets are a component of blood that contribute to the formation of blood clots in the body to prevent bleeding. Patients with<unk>  usually appear normal. Physical examination of patients with<unk>  is usually remarkable for jaundice, hepatosplenomegaly, and lymphadenopathy.
Laboratory findings consistent with the diagnosis of<unk>  include anemia, direct coombs test positive, and antineutrophil antibody positive. Pharmacologic medical therapies for<unk>  include prednisone, intravenous immunoglobulin, and rituximab. Surgery is not the first­line treatment option for patients with<unk> . Splenectomy is usually reserved for patients who are unresponsive to treatment.
Evans syndrome
Mosse syndrome
Mann syndrome
Morvan's syndrome
Branchio-oto-renal syndrome
Amelo-cerebro-hypohidrotic syndrome
Dykes-Markes-Harper syndrome
Bartter syndrome