<unk>  is an orally active selective estrogen receptor modulator (SERM) which is used in the treatment of breast cancer and is currently the world's largest selling drug for that purpose.<unk>  was discovered by ICI Pharmaceuticals (now AstraZeneca) and is sold under the trade names Nolvadex,® Istubal,® and Valodex.® However, the drug, even before its patent expiration, was and still is widely referred to by its generic name<unk> ."
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