<unk>  is a disorder caused by the deletion of a small part of chromosome<unk> 2. It occurs in approximately 1:4000 births.
The deletion occurs near the middle of the chromosome at a location designated q11.2.
DiGeorge Syndrome (DGS) is a combination of signs and symptoms caused by defects in the development of structures derived from the pharyngeal arches during embryogenesis. Key findings comprises of thymic hypoplasia, hypocalcaemia, outflow tract defects of the heart, and dysmorphic facies.
The manifestations of this syndrome cross all medical specialties, and care of the children and adults can be complex. Many patients have a mild to moderate immune deficiency, and the majority of patients have a cardiac anomaly. Additional features include renal anomalies, eye anomalies, hypoparathyroidism, skeletal defects, and developmental delay. Each child's needs must be tailored to his or her specific medical problems, and as the child transitions to adulthood, additional issues will arise. A holistic approach, addressing medical and behavioral needs, can be very helpful.
22q11.2 deletion syndrome
13q deletion syndrome
9q34 deletion syndrome
Bardet-Biedl syndrome
Prader-Willi syndrome
Chromosome 2p16.1-p15 deletion syndrome
Saethre-Chotzen syndrome
Apert syndrome