Accurate diagnosis requires a collateral history from an informant familiar with the patient's daily function.
The presenting symptom is usually loss of recent memory first, and often difficulty with executive function and/or nominal dysphasia (difficulties in word finding and naming).
Patients also experience loss of episodic memory that is marked by, for example, loss of recall of the names of recent visitors, and may exhibit confabulation, confusion, and marked distortions of memory. Globally, an estimated 47 million people are affected by<unk> . In the United States in 2011, there were an estimated 4.5 million individuals over the age of 65 years living with clinical AD; this included 0.7 million people age 65 to 74 years, 2.3 million age 75 to 84, and 1.8 million 85 years and older
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