In 1941,<unk>  was recognized as a complication of<unk>  infection among pregnant women who became infected with the virus early in their pregnancy. An Australian ophthalmologist made the connection and reported 78 cases of congenital cataract among infants born to mothers who had a<unk>  infection early in their pregnancy. The pathogenesis of<unk>  is multifactorial. However, pregnant women who are not vaccinated against<unk>  are at high risk of contracting the infection. If they get infected during pregnancy, the virus can infect the placenta and spread to the fetus, leading to disruption of the normal process of organogenesis.<unk>  virus has largely been eradicated in many parts of the developed world. However, in the developing world where MMR vaccine is not available or accessible, infection with<unk>  and consequently,<unk>  is an important health issue. Many of the congenital infections have overlapping features and hence, congenital<unk>  must be differentiated from the other TORCH infections.<unk>  affects multiple organ systems. The classic triad consists of cataracts, sensorineural hearing loss and patent ductus arteriosus (PDA).
Congenital rubella syndrome
Neonatal malaria
Congenital CMV
Congenital syphilis
Congenital Toxoplasmosis
Neonatal tetanus
Neonatal herpes simplex
Neonatal lupus erythematosus