<unk>  (autosomal dominant), also known as<unk> , is a human gene.
This gene encodes a member of the<unk>  protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. The encoded protein may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homoeostasis and other signal transduction pathways. This protein interacts with<unk>  1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal dominant<unk><unk>  disease.
Polycystic kidney disease 2
Medullary cystic kidney disease
Medullary sponge kidney
Horseshoe kidney
Multicystic dysplastic kidney
Cystic nephroma
Alport syndrome
Renal amyloidosis