Since the syndrome was first described in 2000, < 30 cases have been identified. The median age of presentation in adults is 30 years. The overall prevalence of SQTS is is 0.02 to 0.1% in adults and 0.05% in the pediatric population. In Japanese cohort study of  114,334 patients, prevalence was found to be 0.37 %. In an American cohort of 46,129 prevalence was nearly 2 percent. The Swiss cohort of 1767 patients and Finnish cohort of 10,822 patients had a prevalence of 1 and 0.4 percent respectively.There is a higher male predominance with higher penetrance despite it being autosomal dominant. The mean age of presentation in 30 years.
According to a few studies prevalence of<unk> <unk>  interval is 0.02 to 0.1% in adults and it is believed to be 0.05% in the pediatric population.
Inability to identify the risks associated with<unk> <unk>  interval has led to failure in knowing precise prevalence in adults but it appears to be less than 2 percent if a cut off of 360 milliseconds is used. Studies with large cohorts have made attempts to identify how frequently could SQTS occur in the general population.
In a Japanese cohort of 114,334 patients with ECGs stored in an electronic database, 0.37 percent were found to have<unk> <unk> c intervals (≤357 milliseconds in males, ≤364 milliseconds in females) .
In an American cohort of 46,129 healthy volunteers (53 percent female), nearly 2 percent had a<unk> c interval ≤360 milliseconds .
In a Swiss cohort of 41,767 army conscripts (99.6 percent male, mean age 19 years), 1 percent had a<unk> <unk> c interval (<347 milliseconds), and 0.02 percent had a very<unk> <unk> c interval (<320 milliseconds) .
In a Finnish cohort of 10,822 middle-aged (mean 44 years) patients, 0.4 percent had a<unk> <unk> c interval (<340 milliseconds), and 0.1 percent had a very<unk> <unk> c interval (<320 milliseconds) 
The median age of presentation is 30 years but ranges from just weeks to the sixth decade of life.
SQTS is believed to affect both males and females equally due to the autosomal dominant nature of the disease. Although, A few studies believe it affects males more than females with high penetrance in males.
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