<unk>  or chronic beryllium disorder (CBD) is a chronic allergic-type lung response and chronic lung disease caused by exposure to beryllium and its compounds. The condition is incurable but symptoms can be treated.<unk>  was first discovered by Dr. Harriet Hardy, an American pathologist, in 1945 following an outbreak of respiratory illnesses affecting nearby factory workers.<unk>  may be classified as a rare disorder and an occupational disease. Exposure to beryllium can cause cell-mediated immunity. In each subsequent exposure macrophages and CD4+ helper T - lymphocytes accumulation in the lungs. As a result macrophages, CD4+ helper T - lymphocytes and plasma cells accumulate to form noncaseating granulomas that cause fibrosis. Granulomas are seen in other chronic diseases, such as tuberculosis, sarcoidosis, and it can occasionally be hard to distinguish<unk>  from these disorders.
Berylliosis
Tungiasis
Necatoriasis
Byssinosis
Chalicosis
Strongyloidiasis
Trichinosis
Trichiasis