<unk>  is a systemic immune disease that may develop after an infection with Streptococcus bacteria, such as strep throat and scarlet fever. It usually affects the heart, joints, blood vessels, and brain. Based on the duration of symptoms,<unk>  may be classified into either acute or chronic. The most common cause of<unk>  is Group A beta-hemolytic streptococci infection. If left untreated,<unk>  may cause valvular diseases including stenosis, regurgitation of mitral/aortic valves and myocarditis. This may lead to decreased cardiac output, pulmonary edema, and ultimately cardiac failure. For cases without carditis,  the prognosis is excellent, demonstrating no residual heart disease. In cases with preexisting heart disease, the prognosis is poor, leading to mortality. Common complications of<unk>  include arrhythmias, systemic emboli, and stroke. Common physical examination findings include fever, cardiac murmurs, and erythema marginatum. Echocardiogram and radiograph may be diagnostic of<unk> . The Jones criteria is used to establish the diagnosis of<unk> .<unk>  is usually treated using antibiotics to control Streptococcus infection and medications such as aspirin and corticosteroids to decrease inflammation. A long-lasting dose of penicillin is important and effective to prevent further complications and recurrence.
Rheumatic fever
Lyme disease
Cotton fever
Typhoid fever
Scarlet fever
Rabies
Boutonneuse fever
Periodic fever syndrome