<unk>  <unk> , also known as vacuum assisted closure) is a technique of<unk>  closure used to promote healing in large or chronic<unk> s, fight infection and enhance healing of burns.  A vacuum is used to reduce<unk>  around the<unk> , drawing out excess fluids and cellular wastes.
A Cochrane Review reviewed studies published regarding<unk>  and stated that there was no evidence that the procedure significantly increased the healing time of<unk> s compared to alternative treatment, calling for more and better research to be performed before a final conclusion could be reached.<unk>  seals the<unk>  with a gauze or foam dressing and applies<unk><unk>  to the<unk>  bed with a tube threaded through the dressing.  The vacuum may be applied continuously or intermittently, depending on the type of<unk>  being treated and the clinical objectives.  Intermittent removal of used instillation fluid supports the cleaning and drainage of the<unk>  bed and the removal of infectious material.
Negative pressure wound therapy
Split thickness skin graft
Skin grafting
Surgical suture
Amputation of the leg or foot
Lost-wax casting
Foreskin restoration
Incision and drainage