<unk>  is a medical term for a defect in the body's mechanism for blood clotting.  While there are several possible causes they generally result in excessive bleeding and a lack of clotting.
Hemophilia is one type of congenital disease characterized by<unk> ; these are examples of severe lack of blood clotting.
Coagulopathy
Leukostasis
Neurotoxicity
Encephalopathy
Hepatotoxicity
Cardiotoxicity
Pancytopenia
Anemia