<unk>  is a well-known progressive condition, which has been reported with varying incidence rates. It refers to extracellular deposition of light chains of some serum proteins, that assume a beta pleated structure. Myocardial involvement results in congestive heart failure and fatal arrhythmias and is the leading cause of death in patients with<unk> . Systemic<unk>  of AL and TTR type is often associated with amyloid deposition in heart valves, in addition to blood vessels and myocardium. In this classical type of valvular<unk> , the deposits occur in previously unaltered valves. There is also another type of<unk>  restricted entirely to the heart valves (surgically removed for chronic valvular disease) or only the atria (also called isolated atrial<unk> . This condition is heavily under-diagnosed because the thickening of ventricles from extracellular deposition of amyloid material in the heart is mostly attributed to chronic hypertension, which is also a feature of<unk> .<unk>  should be suspected in the following scenarios:
Congestive heart failure and an increase in left ventricular wall thickness (> 12 mm) in the absence of hypertension or other causes of increased left ventricular mass
Congestive heart failure and an increase in left ventricular wall thickness (> 12 mm) in the absence of hypertension or other causes of increased left ventricular mass in an African-American > 60 years old
Congestive heart failure with preserved left ventricular ejection fraction fraction (HFPEF) in an individual > 60 years old
Congestive heart failure in an individual (particularly an elderly male) with unexplained neuropathy, bilateral carpal tunnel syndrome without risk factors, atrial fibrillation
Signs or symptoms in an individual with a family history of<unk> 
Individuals with hyperenhancement on<unk>  Magnetic Resonance (CMR) or echogenicity on echocardiography
Cardiac amyloidosis
Eosinophilic cardiomyopathy
Alcoholic cardiomyopathy
Dilated cardiomyopathy
Noncompaction cardiomyopathy
Restrictive cardiomyopathy
Multivessel coronary artery disease
Hypertrophic cardiomyopathy