<unk>  (or<unk><unk>  protein) <unk> s) is implicated in addressing system of vesicular transport. For example, Rab is GDP-bound and inactive in the cytosol before contact with<unk> . The membrane-bound<unk>  catalyses the removal of GDP and GDI (GDP dissociation inhibitor) and their replacement with GTP. This allows the Rab protein to bind budding vesicles (e.g., clathrin-coated vesicles). Un-coating of the vesicle allows an interaction between Rab and Rab effector (at the target site), which aids SNARE protein interactions.
Guanine nucleotide exchange factor
GTPase activating protein
Adenylate cyclase
Serine/threonine-specific protein kinase
Adenylate kinase
Receptor tyrosine kinase
Cyclin-dependent kinase
Caspase