<unk>  is a rare soft-tissue<unk>  defined by the presence of a unique translocation, t(X;18)(q11.2;p11.2). It usually occurs adjacent to joints in the limbs and was originally thought to arise from synovium.
However,<unk>  is a misnomer and the origin of the tissue is unknown. Primary<unk> s have been documented in most human tissues and organs, including the brain, prostate and heart.<unk>  occurs most commonly in adolescents and young adults. Diagnosis is based on histology; there are three major histologic subtypes: monophasic (consisting on sheets of spindle cells), biphasic (spindle cells admixed with areas of epithelial differentiation) and poorly differentiated. Immunohistochemical techniques can help, however the gold standard for diagnosing<unk>  is detection of t(X;18) by cytogenetics, FISH or RT-PCR. Despite treatment, prognosis is generally poor, with approximately 50% of patients dying from local reccurrence or metastasis within 10 years.
Synovial sarcoma
Osteochondroma
Osteoblastoma
Osteosarcoma
Ewing's sarcoma
Chondrosarcoma
Osteoma
Osteochondrosis