<unk>  is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Mucobrox, Mucol, Lasolvan, Mucoangin, Surbronc, Ambolar, and Lysopain. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the respiratory tract, which play an important role in the body’s natural defence mechanisms. It stimulates synthesis and release of surfactant by type II pneumocytes. Surfactant acts as an anti-glue factor by reducing the adhesion of mucus to the bronchial wall, in improving its transport and in providing protection against infection and irritating agents.<unk>  is often administered as an active ingredient in cough syrup.<unk>  is indicated as "secretolytic therapy in bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport. It promotes mucus clearance, facilitates expectoration and eases productive cough, allowing patients to breathe freely and deeply".
There are many different formulations developed since the first marketing authorisation in 1978.<unk>  is available as syrup, tablets, pastilles, dry powder sachets, inhalation solution, drops and ampules as well as effervescent tablets.<unk>  also provides pain relief in acute sore throat. Pain in sore throat is the hallmark of acute pharyngitis. Sore throat is usually caused by a viral infection. The infection is self limited and the patient recovers normally after a few days. What is most bothering for the patient is the continuous pain in the throat maximized when the patient is swallowing. The main goal of treatment is thus to reduce pain. The main property of<unk>  for treating sore throat is the local anaesthetic effect, described first in the late 1970s, but explained and confirmed in more recent work.<unk>  is a potent inhibitor of the neuronal Na+ channels. This property led to the development of a lozenge containing 20 mg of<unk> . Many state-of-the-art clinical studies have demonstrated the efficacy of<unk>  in relieving pain in acute sore throat, with a rapid onset of action, with its effect lasting at least three hours.<unk>  is also anti-inflammatory, reducing redness in a sore throat.<unk>  has recently been shown to increase activity of the lysosomal enzyme glucocerebrosidase.  Because of this it may be a useful therapeutic agent for both Gaucher disease and Parkinson's disease.
Ambroxol
Oxaceprol
Dronabinol
Mifepristone
Pixantrone
Dextropropoxyphene
Pipradrol
Norfenefrine