<unk>  therapy is recommended as palliative care among patients who develop advanced stage of large cell<unk>  of the lung or symptomatic patients with local involvement (pain, vocal cord paralysis, and hemoptysis). Curative<unk>  therapy may be indicated in patients who are not suitable for surgery with early stage large cell<unk>  of the lung. The main goal of<unk>  therapy for large cell<unk>  of the lung is maximum tumor control with minimal tissue toxicity. There are 2 main types of<unk>  therapy for large cell<unk>  of the lung: external beam<unk>  therapy and brachytherapy (internal<unk>  therapy).<unk>  therapy for large cell<unk>  of the lung, includes:
Curative intent<unk>  therapy
Palliative<unk>  therapy
Indications for<unk>  therapy in large cell<unk>  of the lung, include:
Sufficient pulmonary reserve
Stage I
Stage II without fitness for surgery
Stage IIIA or IIIB squamous cell<unk>  of the lung and are not fit for chemoradiation
Common types of external beam<unk>  therapy for the treatment of large cell<unk>  of the lung, include:
Three-dimensional conformal<unk>  therapy
Intensity modulated<unk>  therapy
Stereotactic body<unk>  therapy
Stereotactic radiosurgery
Shown below is a list of the different regimens<unk>  therapy for patients with non-small cell lung cancers. The list of regimens has been adapted from the 2014 NCCN Non-Small Cell Lung Cancer guidelines.
Administer fractions of 2 Gy over a period of 6 to 7.5 weeks to a total dose of 60 to 74 Gy
Administer fractions of 1.8 to 2 Gy over a period of 5 weeks to a total dose of 45 to 50 Gy
Negative surgical piece margins: Administer fractions of 1.8 to 2 Gy over a period of 5 to 6 weeks to a total dose of 40 to 54 Gy
Positive surgical piece margins: Administer fractions of 1.8 to 2 Gy over a period of 6 weeks to a total dose of 54 to 60 Gy
Extracapsular nodal extension: Administer fractions of 1.8 to 2 Gy over a period of 6 weeks to a total dose of 60 to 70 Gy
Residual tumor: Administer fractions of 2 Gy over a period of 6 to 7 weeks to a total dose of 54 to 60 Gy
Peripheral small tumors: 25 to 34 Gy not fractioned.
Peripheral tumors and chest wall tumors larger than 1 cm: 45 to 60 Gy administered in 3 fractions
Central or peripheral tumors smaller than 5 cm:  48 to 60 Gy administered in 4 fractions
Central or peripheral tumors principally chest wall tumors smaller that 1 cm: 50 to 55 Gy administered in 5 fractions
Central tumors: 60 to 70 Gy administered in 8 to 10 fractions
Large cell carcinoma of the lung radiation therapy
Squamous cell carcinoma of the lung radiation therapy
Non small cell lung cancer radiation therapy
Large cell carcinoma of the lung medical therapy
Small cell carcinoma of the lung medical therapy
Squamous cell carcinoma of the lung medical therapy
Squamous cell carcinoma of the lung chemotherapy
Non small cell lung cancer chemotherapy