<unk> (oral) is an analgesic opioid that is FDA approved for the {{{indicationType}}} of pain, when opioid analgesics are appropriate, pain (moderate to severe), opioid-tolerant, pain (severe), in opioid-tolerant patients requiring a long-term daily around-the-clock opioid analgesic.. There is a Black Box Warning for this drug as shown here.  Common adverse reactions include dermatologic: flushing (extended-release, less than 2% ), pruritus (extended-release, 1% to 8% ), sweating,gastrointestinal: constipation (extended-release, 7% to 31% ), nausea (extended-release, 9% to 28% .), vomiting (extended-release, 6% to 14% ), neurologic: asthenia (1% to 11% ), dizziness (1% to 11% ), headache (1% to 12% ), somnolence (less than 2% ).
Hydromorphone 
Oxymorphone 
Morphine 
Nalorphine
Normorphine
Ropivacaine
Butorphanol 
Meperidine 