An<unk>  is an altered<unk> , different from the<unk>  secreted by the human pancreas, but still available to the human body for performing the same action as human<unk> . Through genetic engineering of the underlying DNA, the amino acid sequence of<unk>  can be changed to alter its ADME (absorption, distribution, metabolism, and excretion) characteristics.
These modifications have been used to create two types of<unk> s: those that are more readily absorbed from the injection site and are therefore acting faster than natural<unk> , intended to supply the bolus level of<unk>  needed after a meal; and those that are released slowly over a period of between 8 and 24 hours, intended to supply the basal level of<unk>  for the day.
Insulin analog
Glucagon-like peptide-1 analog
Thiazolidinedione
Monoclonal antibodies
Immunoconjugate
Insulin aspart
Antiandrogen
Neuroactive steroid