Physiologically, contraction of the myometrium occurs in response to oxytocin, therefore, mediates the<unk>  hemostasis by mechanically compressing the blood vessels supplying the placenta. The<unk>  is caused by inadequate contraction of the myometrium following the delivery.<unk>  must be differentiated from other diseases that cause postpartum hemorrhage, such as retained placental tissue, obstetric lacerations,  placenta accreta spectrum (placenta accreta, increta, and percreta),<unk>  inversion, maternal coagulation defects, and disseminated intravascular coagulation (DIC).<unk>  is responsible for up to 80% of cases of postpartum hemorrhage, and approximately 25% of maternal deaths are due to postpartum hemorrhage, which is the leading cause of maternal deaths. The presence of a large, soft and boggy uterus on physical examination is highly suggestive of<unk> . The mainstay of treatment for<unk>  is bimanual<unk>  massage with the administration of oxytocin (IV or IM) simultaneously. If oxytocin fails, second-line pharmacologic agents (methylergonovine or carboprost) should be considered. If medical therapy fails, surgical procedures such as<unk>  compression sutures (brace sutures) should be considered.
Uterine atony
Dysfunctional uterine bleeding
Uterine rupture
Hyperemesis gravidarum
Ovarian hyperstimulation syndrome
Endometrial hyperplasia
Abnormal uterine bleeding
Enlarged uterus