Brain MRI is helpful in the diagnosis of delayed puberty. Findings on MRI suggestive of delayed puberty include hypothalamo-pituitary lesions, aplasia of olfactory bulb and/or sulci (Kallmann syndrome), optic nerve compression (pituitary adenoma), and inner ear abnormalities (CHARGE syndrome). Aplasia of olfactory bulbs and/or sulci in MRI is the main differentiation of Kallmann syndrome from isolated hypogonadotropic hypogonadism, in the patient without smelling problems or hard to evaluate.
Delayed puberty MRI
Delayed puberty CT
Androgen insensitivity syndrome MRI
Delayed puberty physical examination
Hypogonadism MRI
Androgen insensitivity syndrome CT
21-hydroxylase deficiency physical examination
Growth hormone deficiency physical examination