<unk> s (EC 3.5.1.98,<unk>  are a class of enzymes that remove acetyl groups (O=C-CH3) from an ε-N-acetyl lysine amino acid on a<unk> , allowing the<unk> s to wrap the DNA more tightly. This is important because DNA is wrapped around<unk> s, and DNA expression is regulated by acetylation and de-acetylation. Its action is opposite to that of<unk>  acetyltransferase.<unk>  proteins are now also called lysine<unk> s (KDAC), to describe their function rather than their target, which also includes non-histone proteins.
Histone deacetylase
Caspase
Cyclin-dependent kinase
Phosphatase
Guanine nucleotide exchange factor
GTPase activating protein
DNA glycosylase
Adenylate cyclase