PPGLs arise from chromaffin cells in the adrenal medulla or in extra-adrenal neural ganglia. PPGLs are related to several hereditary syndromes and many of the sporadic cases present germline mutations. Chromaffin cells are involved in the production of catecholamines, hence, these tumors can be biochemically active.
Paraganglioma pathophysiology
Ganglioglioma pathophysiology
Schwannoma pathophysiology
Meningioma pathophysiology
Myxoma pathophysiology
Glomus tumor pathophysiology
Glioma pathophysiology
Ameloblastoma pathophysiology