<unk>  is a complication of long-standing and poorly controlled diabetes mellitus. Poor glycemic control, peripheral neuropathy, improper footwear, ischemia and possible foot deformities including charcot arthropathy are the main known causes of<unk> . A detailed history of the patient's diabetes status, foot care, deformities, foot hygiene, symptoms of ischemia, and history of smoking is necessary to classify the wound or ulcer and treat the underlying cause. Physical examination includes an assessment of the ulcer and tests to detect the severity of peripheral neuropathy (such as Semmes-Weinstein monofilament test) and ischemia (such as Ankle-Brachial Index (ABI)). Routine laboratory investigations are recommended, such as HbA1c. If an infection is suspected, a wound culture is necessary to guide antibiotic therapy. Mechanical offloading such as cast walkers, total contact casting or therapeutic shoes, and podiatric care are essential. Surgical interventions, such as revascularization surgery) may be considered for patient's with ischemia.  Antibiotic therapy is based on culture, risk of MRSA infection, risk of pseudomonas infection, presence or absence of complications, such as osteomyelitis and history of recent antibiotic use. Hyperbaric oxygen therapy is considered for a<unk>  that persists despite treatment for more than 30 days.
Diabetic foot
Raynaud's disease
Leg ulcer
Athlete's foot
Foot rot
Buerger's disease
Gangrene
Gangrene 