<unk>  (activated) (Xigris, marketed by Eli Lilly and Company) is a recombinant form of human activated protein C that has anti-thrombotic, anti-inflammatory, and profibrinolytic properties.<unk>  alpha (activated) belongs to the class of serine proteases.<unk>  has not been found to improve outcomes in people with severe sepsis. The manufacturer's aggressive strategies in marketing its use in severe sepsis have been criticized.  On October 25, 2011, Eli Lilly & Co. withdrew Xigris from the market after a major study showed no efficacy for the treatment of sepsis.
Drotrecogin alfa
Etelcalcetide
Trenonacog alfa
Elosulfase alfa
Ceruletide
Desmopressin 
Metreleptin
Peginesatide