<unk> ’s disease is a rare condition characterised by rapid destruction of the kidneys and the lungs. It is a type type II hypersensitivity reaction in which autoantibodies are produced against glomerular basement membrane (GBM) and alveolar basement membrane. The term<unk>  is named after American physician Dr. Ernest William<unk> . There are no known direct causes for<unk> . However,<unk>  must be differentiated from other diseases that cause rapid progressive glomerulonephritis and pulmonary hemorrhage. The prevalence of<unk>  worldwide is an estimated 1 case per million individuals, with high prevalence in Caucasians. Common risk factors in the development of<unk>  may be occupational, environmental, genetic, and viral. Symptoms of<unk>  include, malaise, pyrexia and chills and arthralgia, fatigue, lethargy, pallor, and anorexia. Laboratory findings consistent with the diagnosis of<unk>  include presence of autoantibodies such as  anti-glomerular basement membrane antibodies. Other diagnostic studies for<unk>  include renal biopsy. The mainstay of therapy for<unk>  consist of corticosteroids, cyclophosphamide and plasmapheresis.
Goodpasture syndrome
IMAGE syndrome
Wegeners granulomatosis
Churg-Strauss syndrome
DRESS syndrome
MOMO syndrome
Hamman-Rich syndrome
Hypereosinophilic syndrome