The prevalence of<unk>  is approximately 1 per 100,000 individuals worldwide.<unk>  is a disease that tends to affect the middle-aged and elderly population with a mean age of 60 years at diagnosis. Males are more commonly affected than females. The male to female ratio is approximately 1.5 to 1.<unk>  usually affects individuals of the Ashkenazi Jews race. African American, Latin American, and Asian individuals are less likely to develop<unk> .
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