<unk>  (EC 1.4.99.1) is a bacterial enzyme that catalyses the oxidation of D-amino<unk> s into their corresponding oxoacids. It contains both flavin and nonheme iron as cofactors. The enzyme has a very broad specificity and can act on most D-amino<unk> s.
D-amino<unk>  + H2O + acceptor <=> a 2-oxo<unk>  + NH3 + reduced acceptor
This reaction is distinct from the oxidation reaction catalysed by D-amino<unk>  oxidase that uses oxygen as a second substrate, as the dehydrogenase can use many different compounds as electron acceptors, with the physiological substrate being coenzyme Q.
D-amino acid dehydrogenase
Glucose-6-phosphate dehydrogenase
Aldehyde dehydrogenase
Formate dehydrogenase
Oxoglutarate dehydrogenase
Succinate dehydrogenase
Phosphoglucomutase
Pyruvate decarboxylase