Some mutations and genetic factors are thought to play a role in the pathogenesis of B-cell prolymphocytic leukemia. Some known mutations are: p53 gene mutation, 11q23 and 13q14 deletions and deletions from chromosome 11 and chromosome 13.
Genetic mutations like mutation or loss of p53 is thought to play a role.
11q23 and 13q14 deletions are associated with B cell prolymphocytic leukemia.
t(11;14) translocation rembles the mutation of mantle cell lymphoma, which makes it harder for the clinicians to distinguish the two entities.
It can involve deletions from chromosome 11 and chromosome 13.
B-cell prolymphocytic leukemia causes
Hairy cell leukemia causes
Acute myeloid leukemia causes
B-cell lymphoma causes
Chronic myelogenous leukemia causes
B-cell prolymphocytic leukemia risk factors
Autoimmune lymphoproliferative syndrome causes
Myeloproliferative neoplasm causes