<unk>  is an inherited disorder that causes ammonia to accumulate in the blood. Ammonia is toxic, especially to the nervous system, and<unk>  usually becomes evident in the first few days of life.
An infant with<unk>  may seem lethargic or be unwilling to eat, have poorly-controlled breathing rate or body temperature, experience seizures or unusual body movements, or go into a coma. Complications from<unk>  may include developmental delay and mental retardation. Progressive liver damage, skin lesions, and brittle hair may also be seen. Immediate treatment and lifelong management (following a strict diet and using appropriate supplements) may prevent many of these complications.
Occasionally, an individual may inherit a mild form of the disorder in which ammonia accumulates in the bloodstream only during periods of illness or other stress.
Argininosuccinic aciduria
Homocystinuria
Phenylketonuria
3-Methylglutaconic aciduria
Mevalonic aciduria
Alkaptonuria
Glutaric aciduria type 1
Familial hyperchylomicronemia