Patients can be both resistant and hypersensitive to<unk> s.
In<unk> , the target tissue is unable to respond to<unk> s. The lack of responsiveness can be
The presence of complete<unk>  is fatal.  Absence of functional<unk>  receptors (GRs) in GR -/- knockout mice is associated with death within hours.
Glucocorticoid resistance
Insulin resistance
Thyroid hormone resistance
Secondary adrenal insufficiency
Multiple endocrine neoplasia
21-hydroxylase deficiency
ACTH-secreting tumor
Critical illness-related corticosteroid insufficiency