<unk>  (INN) or inamrinone (USAN, changed in 2000 to prevent confusion with amiodarone), trade name Inocor, is a pyridine phosphodiesterase 3 inhibitor.  It is a drug that may improve the prognosis in patients with congestive heart failure.<unk>  has been shown to increase the contractions initiated in the heart by high gain calcium induced calcium release (CICR). The positive inotropic effect of<unk>  is mediated by the selective enhancement of high gain CICR which contributes to the contraction of myocytes by phosphorylation through cAMP dependent protein kinase A (PKA) and Ca2+ calmodulin kinase pathways.
Amrinone
Adenosine
Propafenone
Etafenone
Boldenone
Nitroprusside
Verapamil
Bevantolol