The epithelial cell lining the bile ducts are called cholangiocytes. The malignant transformsation of cholangiocytes leads to<unk> . Malignant transformation of cholangiocytes into<unk>  include hyperplasia, metaplasia and dysplasia. Biliary intraepithelial neoplasia is believed to be the initial lesion of<unk> , particularly in patients with hepatolithiasis in bile ducts. Gross pathologic features characteristic to intrahepatic<unk>  are divided in three subtypes and include mass forming type, periductal infiltrating type, and intraductal growth type.  On microscopic pathology, characteristic findings of<unk>  include cuboidal or columnar mucin producing cells and dense fibrous (desmoplastic) stroma.
Cholangiocarcinoma pathophysiology
Hepatocellular carcinoma pathophysiology
Gallbladder cancer pathophysiology
Cholangitis pathophysiology
Alcoholic hepatitis pathophysiology
Peliosis hepatis pathophysiology
Biliary cystadenoma and cystadenocarcinoma pathophysiology
Hepatocellular adenoma pathophysiology