<unk>  is a condition that develops because of long-term partial or total obstruction of the large bile ducts outside of the liver (known as the common bile duct and its major branches). When the ducts are damaged, bile (which is a substance that helps digest fat) builds up in the liver and damages the liver tissue. Over time, the<unk>  can progress and even make the liver stop working.
Causes of<unk>  may include:
Narrowing (strictures) of the bile duct following gallbladder surgery
Gallstones
Chronic pancreatitis
Pericholangitis
Idiopathic sclerosing cholangitis
Congenital<unk>  atresia
Cystic fibrosis.
Secondary Biliary Cirrhosis
Alcoholic hepatitis
Ischemic hepatitis
Autoimmune hepatitis
Benign intrahepatic cholestasis
Alcoholic liver disease
Alcoholic hepatitis surgery
Primary biliary cirrhosis