First-line therapies include bortezomib, lenalidomide, dexamethasone, melphalan, and cyclophosphamide. Second-line therapies (used for relapsed or refractory disease) include ixazomib, carfilzomib, daratumumab, elotuzumab, and pomalidomide. Autologous stem cell transplant is done after remission is achieved with chemotherapy. The choice of the treatment regimen partly depends on transplant eligibility. Supportive therapy is an important component of care while patients are receiving anti-cancer therapy.
Multiple myeloma medical therapy
POEMS syndrome medical therapy
Renal cell carcinoma medical therapy
Secondary amyloidosis medical therapy
Familial amyloidosis medical therapy
Primary amyloidosis medical therapy
Multiple myeloma surgery
Myelofibrosis medical therapy