Tests based on monoclonal antibodies and immunofluorescence, including treponema pallidum hemagglutination assay (TPHA) and fluorescent treponemal antibody absorption (FTA-ABS) are more specific and more expensive.
Following positive non-treponemal tests, FTA-ABS is commonly used to confirm the diagnosis. Sensitivity ranges from 84% for detection of primary infection to approximately 100% for the diagnosis of other stages with a specificity of 96%.
Unfortunately, false positives can still occur in related treponomal infections such as yaws and pinta.
Tests based on enzyme-linked<unk> s for immunoglobulin G (IgG) and immunoglobulin M (IgM) are also used to confirm the results of simpler screening tests for syphilis.
Syphilis/Immunoassay
Syphilis/Dark field microscopy
Syphilis/Serology
Syphilis/Laboratory tests
Mononucleosis/Laboratory tests
Nucleic acid test
Leprosy x ray
Tuberculosis/Laboratory Tests