<unk> es are disorders in which part of the body's immune system is missing or does not function properly.  Immunodeficiency syndromes may be caused by disorders of the bone marrow (site of immunocyte production).  However, many<unk>  syndromes are caused by mutations that result in abnormalities in either the maturation of immunocytes or their function and are thus not considered bone marrow disorders per se.  To be considered a<unk> , the cause of the immune deficiency must not be secondary in nature (i.e., caused by other disease, drug treatment, or environmental exposure to toxins, e.g.).  In<unk> , there might be either cellular involvement (T-cells), humoral involvement (B-cells), or both cellular and humoral involvement.
Primary immunodeficiency
Combined immunodeficiency
Severe combined immunodeficiency
Selective immunoglobulin A deficiency
Common variable immunodeficiency
IgG deficiency
X-linked agammaglobulinemia
Immunoglobulin M deficiency