TIMI<unk> <unk>  flow is a term developed by Dr. C. Michael Gibson, M.S., M.D. to describe hyperemic flow on a coronary arteriogram. Hyperemic flow on a coronary arteriogram is defined qualitatitively as near instantaneous filling of the coronary artery with dye, and quantitatively as a corrected TIMI frame count < 14 frames. Hyperemic flow in a coronary artery may be due to either repayment of oxygen debt following ischemia due to a balloon inflation for instance, or distal embolization.  If it is due to distal embolization, and if impaired myocardial perfusion is present (TIMI myocardial perfusion<unk>  0 or TIMI myocardial perfusion<unk>  1), then the mortality associated with TIMI<unk> <unk>  flow is actually higher than that of TIMI<unk>  3 flow.  In this scenario, the hyperemic flow is a surrogate or marker of endogenous adenosine release due to distal embolization, rather than being causally related to adverse outcomes.
TIMI flow grade 4
TIMI flow grade 3
TIMI flow grade 0
TIMI flow grade 2
TIMI flow grade 1
TIMI thrombus grade 0
TIMI thrombus grade 5
TIMI thrombus grade 3