Adrenal<unk>  is a condition in which the adrenal glands, located above the kidneys, do not produce adequate amounts of steroid hormones, primarily cortisol, but may also include impaired aldosterone production (a mineralocorticoid) which regulates electrolytes mainly sodium and potassium along side with water retention. Craving for salt or salty foods due to the urinary losses of sodium is common.
Adrenal<unk>  can also occur when the hypothalamus or the pituitary gland, both located at the base of the skull, does not make adequate amounts of the hormones that assist in regulating adrenal function. This is called<unk>  and is caused by lack of production of ACTH in the pituitary or lack of CRH in the hypothalamus. Accordingly, it is classified in to 2 types, primary adrenal<unk>  and<unk> . It must be differentiated from other diseases that may cause hypotension, fatigue, and skin pigmentation. The most potent risk factor in the development of<unk>  is infections, such as Tuberculosis. Its common complications include hypoglycemia, adrenal crisis,hypovolemic shock and cardiac arrest. Prognosis is generally good in patients with<unk>  as long as they are on life-time hormonal therapy. The most common symptoms of<unk>  include Chronic fatigue, weight loss, and visual field defects. The main stay of treatment for<unk>  is treating the underlying cause. For symptomatic cases, hydrocortisone should be administered. The long-term treatment goal is to maintain normal blood pressure, blood glucose, fluid volume, and a sense of well-being in the patient.
Secondary adrenal insufficiency
Congenital adrenal hyperplasia
Lipoid congenital adrenal hyperplasia
Autoimmune polyendocrine syndrome
Multiple endocrine neoplasia
Hypopituitarism
ACTH-secreting tumor
Syndrome of inappropriate antidiuretic hormone surgery