<unk>  is usually discovered in childhood, occasionally in adulthood. The male-to-female ratio is usually 1:1. It can occur in a single limb, and the lower extremity is more commonly affected than the upper extremity. The epicenter is periosteal or endosteal. The appearance consists of cortical hyperostosis in one or multiple bones, often with intervening soft-tissue calcification or ossification. The limb involved with<unk>  often demonstrates joint pain, swelling, and limitation of motion in childhood. There is often associated growth disturbance, muscular contraction, and limb length discrepancy. There may be overlying skin changes. At pathologic analysis, thickened and enlarged osseous trabeculae are noted, associated with fibrous tissue replacement of the marrow space. There is controversy involving the distribution of<unk> . It has been suggested that the distribution mimics that of the sclerotomes (zones supplied by individual spinal sensory nerves), implying a neurogenic origin.
Melorheostosis
Acrodysostosis
Craniosynostosis
Erythroplasia of Queyrat
Sterculia
Thanatophoric dysplasia
Haff disease
Achondroplasia