<unk> es (PAD) are the most common type of primary immunodeficiency diseases (PID). PAD is a large group of diseases which may vary widely from having a complete absence of B cells and decrease in all immunoglobulins to having deficiency in specific immunoglobulins. Depending on the phenotype, agammaglobulinemia or CVID, patients can present either in infancy or adulthood.The main clinical characteristic of patients with PAD is recurrent bacterial infections, low levels of immunoglobulin (ranging from agammaglobulinemia to hypogammaglobulinemia), and impaired response to vaccines and antigens. Treatment is by intravenous or subcutaneous immunoglobulins and treatment of infections by antibiotics.
Predominantly antibody deficiency
Hypergammaglobulinemia pathophysiology
Autoimmune lymphoproliferative syndrome causes
Cryoglobulinemia causes
Diseases of immune dysregulation
Cryoglobulinemia risk factors
Phenocopies of primary immunodeficiency
Neutropenia causes