<unk>  is a homotetrameric enzyme (EC 4.1.1.1) that catalyses the decarboxylation of pyruvic acid to acetaldehyde and carbon dioxide. It is also called 2-oxo-acid carboxylase, alpha-ketoacid carboxylase, and pyruvic<unk>  .  In aerobic conditions, this enzyme is the first in a three enzyme complex known as the<unk>  dehydrogenase complex, which converts<unk>  (the product of glycolysis) into acetyl CoA.  In anaerobic conditions, this enzyme is part of the fermentation process that occurs in yeast to produce alcohol (this enzyme is not in animals).<unk>  starts this process by converting<unk>  into acetaldehyde and carbon dioxide.  To do this, two thiamine pyrophosphate (TPP) and two Magnesium ions are required as a cofactors.  File:1pvd with TPP.jpg<unk>  with TPP attached
Pyruvate decarboxylase
Phosphoglucomutase
Aldehyde dehydrogenase
Saruplase
D-amino acid dehydrogenase
Oxoglutarate dehydrogenase
Formate dehydrogenase
Glucose-6-phosphate dehydrogenase