<unk>  (also known as<unk> -Cass<unk> ") is defined as the triad of ascites, pleural effusion, and benign ovarian tumor.<unk>  was first discovered by Otto von Spiegelberg, a German gynecologist, in 1866. There is no classification system established for<unk> . Other variants of<unk>  include pseudo-meigs<unk> , and atypical<unk> .<unk>  may be caused by either ovarian fibroma, Brenner tumor, ovarian thecoma, or granulosa cell tumor. The pathogenesis of<unk>  is characterized by a transudative process. The prevalence of benign ovarian tumors is approximately 2-10%, and only 1-2% develop<unk> .<unk>  is more commonly observed among postmenopausal women. The median age at diagnosis is approximately 50 years. The majority of patients with<unk>  are asymptomatic.  Early clinical features include bloating, fatigue, and shortness of breath. Computed tomography is the imaging modality of choice for<unk> . On conventional radiography,<unk>  is characterized by blunting of the costophrenic angle or fluid within the horizontal or oblique fissures (250-600 ml of fluid is required before the pleural effusion becomes evident). Surgery is the mainstay of therapy for<unk> . Exploratory laparotomy with surgical staging is the most common approach to the treatment of<unk> . Once diagnosed and successfully treated, patients with<unk>  are followed-up every 6 months. Follow-up testing includes; serum cancer antigen 125, ultrasound, and basic metabolic profile.
Meigs syndrome
Storm syndrome
Lucey-Driscoll syndrome
Bloom syndrome
Galloway Mowat syndrome
Tietze's syndrome
Hartnup Disease
Zieve's syndrome