The<unk>  <unk>  is the causative agent of hepatitis E.  It is a member of the genus Hepevirus that belongs to the Hepeviridae family.  It is a nonenveloped, single-stranded positive-sense RNA virus.  The genome of<unk>  contains 3 Open reading frames: ORF 1, ORF 2, and ORF 3.  The RNA genome acts as a template for viral replication, structural and nonstructural protein synthesis.  Five different genotypes have been identified, all belonging to the same serotype. Depending on the genotype, epidemiological and clinical manifestations will be different: genotypes 1 and 2 only cause disease in humans, and are transmitted through water and fecal-oral route, while genotypes 3 and 4 cause disease in animals, having humans as accidental hosts, and are transmitted through the consumption of undercook meat. The<unk>  replicates within the host cell's cytoplasm, however, its cellular receptor, and mechanism of entry remain unknown.
Hepatitis E Virus
Hepatitis D Virus
Hepatitis B virus
Hepatitis C virus
Hepatitis A virus
Epstein Barr virus
Rubella virus
HIV