<unk>  found in the intestine of a newborn, consisting of succus entericus (bile salts, bile acids, and debris from the intestinal mucosa)<unk>  is normally evacuated within 6 hours of birth or earlier.<unk>  occurs with<unk>  becomes inspissated and obstructs the distal<unk> . It is usually a manifestation of cystic fibrosis. It is usually understood as synonymous with cystic fibrosis until proven otherwise. Approximately 20% of infants with cystic fibrosis present with<unk>  at birth. It may also be seen with pancreatic atresia or stenosis of the pancreatic duct. It may rarely occur without cystic fibrosis or pancreatic abnormality in cases likely related to gut immaturity (more favorable outcome). Further complications include ileal atresia or stenosis, ileal perforation,<unk>  peritonitis, and volvulus with or without pseudocyst formation. It is more common in white populations. It affects both sexes almost equally.
Prenatal ultrasound findings associated with<unk>  include polyhydramnios, fetal ascites, peritoneal wall calcifications, and intraabdominal cysts.<unk>  is normally invisible radiographically.
Occassionally, has a mottled appearance on radiographs during the first 2 days of life.
Classically, a paucity or absence of air-fluid levels and a "bubbly" appearance of distended intestinal loops on radiographs.<unk> crocolon seen on barium enema.
Characteristic findings often not seen, and thus relatively unreliable.
Patient #1
Patient #2
Patient #3<unk>  must be differentiated from other diseases that cause a failure to pass<unk>  or abdominal distension in infants, including<unk>  plug syndrome, small left colon syndrome, and congenital hypothyroidism.
Transient intestinal obstruction for 1-2 days after birth.
Obstruction is functional due to dilated colon and delayed passage of feces.
Usually seen in premature infants.
Reduced caliber of the colon starting from splenic flexure and going down, causing intestinal obstruction.
Characterized by a sudden change of the colon diameter.
Usually associated with gestational diabetes.
Failure to pass<unk>  due to failure of intestine recanalization.
Proximal lesions have an earlier onset of symptoms than distal lesions.
Colonic atresia may affect normal children or may be associated with other abnormalities as Hirschsprung's disease or gastroschisis.
Intestinal obstruction due to inspissation of<unk>  in the distal<unk> .
Most cases of<unk>  are secondary to cystic fibrosis.
Typically presents with failure to pass<unk>  and abdominal distension with or without vomiting.<unk>  may first present with complications, including perforation and volvulus.
Most infants are born asymptomatic.
Symptoms, if present, may include, but not limited to:
Macroglossia
Hoarse cry
Umbilical hernia
Puffy facies
Increased head circumference
Hypothermia
Macroglossia
Hoarse cry
Umbilical hernia
Puffy facies
Increased head circumference
Hypothermia
Meconium ileus
Meconium plug syndrome
Meconium aspiration syndrome
Intestinal atresia
Intestinal malrotation
Necrotizing enterocolitis
Situs inversus
Duodenal atresia