Lactic acidosis occurs when cells make lactic acid faster than it can be metabolized.   Both overproduction of lactate, or reduced metabolism, lead to acidosis. Normal lactate levels are less than 2 mmol/L, lactate levels between 2 mmol/L and 4 mmol/L are defined as hyperlactatemia. Severe hyperlactatemia is a level of 4 mmol/L or higher. Other definitions for lactic acidosis include: pH less than or equal to 7.35 and lactatemia greater than 2 mmol/L with a partial pressure of carbon dioxide (PaC02) less than or equal to 42 mmHg.
Lactic acidosis pathophysiology
Metabolic alkalosis pathophysiology
Diabetic ketoacidosis pathophysiology
Respiratory acidosis pathophysiology
Hypoglycemia pathophysiology
Lactic acidosis causes
Hypokalemia pathophysiology
Renal tubular acidosis risk factors