<unk>  patients represent a group of patients who have more comorbidities and who are both at risk for both CAD as well as for associated complications. However, they do derive equivalent or greater benefit from intervention when compared to younger patients. This group is likely to present with atypical symptoms like dyspnea and confusion rather than chest pain. 
On the other hand, presence of<unk> cardiac comorbidities such as chronic obstructive lung disease, gastroesophageal reflux disease, upper-body musculoskeletal symptoms, pulmonary embolism, and pneumonia is also higher, thus making the diagnosis of UA/NSTEMI challenging. 
Secondly, they are more likely to have altered or abnormal cardiovascular anatomy, increased cardiac afterload due to decreased arterial compliance and arterial hypertension, orthostatic hypotension, cardiac hypertrophy, and ventricular dysfunction, especially diastolic dysfunction. 
Thirdly,<unk>  patients generally have other cardiac comorbidities and risk factors, such as hypertension, prior MI, HF, cardiac conduction abnormalities, prior CABG, peripheral and cerebrovascular disease, diabetes mellitus, renal insufficiency, and stroke. 
As a result, they are on mulitple medications and hence at risk for drug interactions and polypharmacy. When considering revascularization procedures, general medical and cognitive status, bleeding risk and other risk of interventions, anticipated life expectancy, and patient or family preferences must be considered.
Unstable angina / non ST elevation myocardial infarction and the elderly
Unstable angina / non ST elevation myocardial infarction and women
Unstable angina / non ST elevation myocardial infarction and post CABG patients
Unstable angina / non ST elevation myocardial infarction risk stratification and prognosis
Sudden cardiac death echocardiography and ultrasound
Unstable angina / non ST elevation myocardial infarction long-term medical therapy and secondary prevention
Unstable angina / non ST elevation myocardial infarction aspirin therapy
Unstable angina / non ST elevation myocardial infarction nitrate therapy