Acute lymphoid leukemia arises from lymphoblasts, which are hematologic white cells that are normally involved in the hematopoiesis. Chromosomal translocations involved in the pathogenesis of acute lymphoid leukemia include translocations between the chromosomes 9 and 22, t(9;22) (q34;q11.2) BCR-ABL1, translocations between the chromosomes 12 and 21, t(12;21)(p13;q22) TEL-AML1, translocations between the chromosomes 5 and 14, t(5;14)(q31;q32)IL3-IGH and translocations between chromosomes 1 and 19 t(1;19)(q23;p13.3) TCF3-PBX1.
Acute lymphoblastic leukemia pathophysiology
Acute myeloid leukemia pathophysiology
Chronic myelogenous leukemia pathophysiology
Hairy cell leukemia risk factors
B-cell prolymphocytic leukemia risk factors
Acute lymphoblastic leukemia risk factors
Myelodysplastic syndrome pathophysiology
Myelodysplastic syndrome risk factors