combination of these two findings on immunophenotyping of frozen section specimen cells and RT-PCR are confirmatory for<unk> <unk> /T cell lymphoma:Detection of CD56 and EBER1 on tumor cells and EBV DNA (RT-PCR).Pathological examination of frozen section specimen may misled the<unk> /T cell diagnosis.Circulating cell free EBV DNA levels by RT-PCR is a diagnostic factor for EBV associated malignancies, Like<unk> <unk> /T cell lymphoma. Measuring both BamHI W DNA and LMP1 DNA is more useful as a prognosis predictor, these DNAs will decrease with treatment and increase with relapse. Recently, determination of negative immune checkpoints are considered as a drug target,in the case of<unk> <unk> /T cell lymphoma, PD-L1 will be expressed in the tumor, and patients with higher concentration of soluble PD-L1 showed worse prognosis.
Extranodal NK-T-cell lymphoma diagnostic study of choice
Mantle cell lymphoma diagnostic study of choice
Angioimmunoblastic T-cell lymphoma diagnostic study of choice
B-cell lymphoma diagnostic study of choice
Diffuse large B cell lymphoma diagnostic study of choice
Follicular lymphoma diagnostic study of choice
Burkitt's lymphoma diagnostic study of choice
Anaplastic large cell lymphoma diagnostic study of choice