<unk>  is rare lymphomas of CD4+ helper T cells.<unk>  was first described in 1806 by French dermatologist Jean-Louis-Marc Alibert. On microscopic histopathological analysis,  atypical lymphoid cells,  polymorphous inflammatory infiltrate in the dermis, and lymphocytes with cerebroid nuclei are characteristic findings of<unk> .<unk>  is caused by a mutation in the T cells.<unk>  must be differentiated from other diseases such as  eczema and psoriasis.<unk>  commonly affects  45 and 55  years. In the United States, males are more commonly affected with<unk>  than females. In the United States,<unk>  usually affects individuals of the African American race.The risk factors in the development of<unk>  is environmental, occupationalexposure to long term exposure to chemicals, virainfection. According to the the U.S. Preventive Service Task Force (USPSTF), there is insufficient evidence to recommend routine screening for cutaneous T cell lymphoma.The staging of<unk>  is based on skin and lymph node involvement.The most common symptoms of<unk>  include fever, weight loss, skin rash, night sweats, itching, chest pain, abdominal pain, and bone pain. Common physical examination findings of<unk>  include fever, rash, pruritus, ulcer, chest tenderness, abdominal tenderness, bone tenderness, peripheral lymphadenopathy, and central lymphadenopathy.Laboratory tests for<unk>  include complete blood count (CBC), blood chemistry studies, flow cytometry, immunohistochemistry,  and immunophenotyping. The definitive diagnosis of<unk>  is confirmed by either a skin biopsy or a lymph node biopsy. CT scanning in<unk>  patients evaluated information such as enlarged lymph node (LN) and metastatic involvement. MRI may be helpful in the diagnosis of<unk> . PET scan may be helpful in the diagnosis of<unk> .Other diagnostic studies for<unk>  include bone marrow aspiration and bone marrow biopsy.The predominant therapy for<unk>  is PUVA. Adjunctive chemotherapy, radiotherapy, biological therapy, retinoid therapy, and photophoresis may be required.
Mycosis fungoides
Sycosis vulgaris
Tinea versicolor
Actinic granuloma
Granuloma faciale
Granulosis rubra nasi
Lichen nitidus
Alopecia mucinosa