<unk>  was first described by Sainton and Millot, in 1933. In 1928, the first<unk> ectomy operation was conducted by Isaac Y. Olch to treat<unk>  lesions. On gross pathology, stony-hard consistency, lobulation, and dense, fibrous, grayish-white capsule are characteristic findings of<unk> . On microscopic histopathological analysis,
dense fibrous trabeculae, mitoses, and capsular invasions are characteristic findings of<unk> . The etiology of<unk>  is unknown.<unk>  must be differentiated from renal disease, immobility, and thiazides adverse effect. The incidence of<unk>  is approximately 0.015 per 100,000 individuals in United States.<unk>  affects men and women equally. Common risk factors in the development of<unk>  are multiple endocrine neoplasia type 1, hyperparathyroidism, and familial isolated hyperparathyroidism. The hallmark of<unk>  is neck mass. A positive history of multiple endocrine neoplasiab type I, hyperparathyroidism, and previous radiation therapy to the head or neck is suggestive of<unk> . The most common symptoms of<unk>  include weight loss, muscle weakness, fractures, constipation, fatigue, and bone pain. Patients with<unk>  usually appear well. Physical examination of patients with<unk>  is usually remarkable for lymphadenopathy and a palpable lump in the neck. Neck CT scan may be diagnostic of<unk> . Laboratory findings consistent with the diagnosis of<unk>  include elevated serum calcium and serum<unk>  hormone. Findings on CT suggestive of<unk>  include metastasis and invasion of surrounding tissues. The predominant therapy for<unk>  is surgical resection. Adjunctive supportive therapy, chemotherapy, and radiation may be required. Supportive therapy for<unk>  includes IV fluids, diuretics, and calcimimetic agents. Surgery is the mainstay of treatment for<unk> . There are no primary preventive measures available for<unk> . Secondary prevention strategy recommended following<unk>  is germline DNA analysis for HRPT2/CDC73.
Parathyroid cancer
Parathyroid adenoma
Thyroid cancer
Papillary thyroid cancer
Follicular thyroid cancer
Medullary thyroid cancer
Thyroid adenoma
Parathyroid disease