Because new<unk>  variants of SQTS are still being identified, a negative<unk>  test for existing variants does not exclude the presence of SQTS.  A negative<unk>  test for existing variants could mean that a patient with a<unk> <unk>  interval does not have a heretofore unidentified variant of SQTS.
However, among family members of an affected patient,<unk>  testing may identify the syndrome in an asymptomatic patient, and may also rule out the presence of the syndrome in asymptomatic patients.
Mutations in the KCNH2, KCNJ2, and KCNQ1 genes cause<unk> <unk>  syndrome. These genes provide instructions for making proteins that act as channels across the cell membrane. These channels transport positively charged atoms (ions) of potassium into and out of cells. In cardiac muscle, these ion channels play critical roles in maintaining the heart's normal rhythm. Mutations in the KCNH2, KCNJ2, or KCNQ1 gene increase the activity of the channels, which changes the flow of potassium ions between cells. This disruption in ion transport alters the way the heart beats, leading to the abnormal heart rhythm characteristic of<unk> <unk>  syndrome.<unk> <unk>  syndrome appears to have an autosomal dominant pattern of inheritance.
Gene Tests:<unk> <unk>  Syndrome 1
Gene Tests:<unk> <unk>  Syndrome 2
Gene Tests:<unk> <unk>  Syndrome 3
Short QT syndrome genetic testing
Catecholaminergic polymorphic ventricular tachycardia genetic testing
Brugada syndrome genetic testing
Coronary artery calcium scoring
Noncompaction cardiomyopathy genetic testing
Catecholaminergic polymorphic ventricular tachycardia exercise stress testing
Dilated cardiomyopathy genetic testing
Cardiac electrophysiology