<unk>  is a form of leukemia or cancer of the white<unk> lood cells. Prolymphocytic leukemia is classified in<unk>  and<unk> ,<unk>  is part of a subclassification of prolymphocytic leukemias. Arises from mature<unk> -cells, which are hematologic white cells that are normally involved in the in the humoral immunity component of the adaptive immune system<unk> y secreting antibodies.<unk>  must<unk> e differentiated from other diseases such as<unk> , chronic lymphocytic leukemia and hairy cell leukemia. The incidence of<unk>  is 1% of lymphocytic leukemias.<unk>  affects men and women equally. The prognosis is generally poor. Symptoms of<unk>  include generalised weakness and, anemia,massive splenomegaly, weight loss, loss of appetite, thrombocytopenia and peripheral lymphadenopathy. Common physical examination findings include tachycardia, pallor, splenomegaly and lymphadenopathy. Laboratory findings consistent with the diagnosis of<unk>  include anemia, lymphocytosis, abnormal<unk> lood chemistry studies and abnormal<unk> lood peripheral smear.<unk> <unk> one marrow<unk> iopsy is considered a definitive diagnosis. Other diagnostic studies include immunophenotyping.
B-cell prolymphocytic leukemia
T-cell prolymphocytic leukemia electrocardiogram
Aggressive NK-cell leukemia
T-cell prolymphocytic leukemia
Adult T-cell leukemia
T-cell large granular lymphocyte leukemia
Prolymphocytic leukemia
B-cell leukemia