The exact pathogenesis of<unk>  fissure is not fully understood but constipation or<unk>  trauma was supposed to instigate the fissure. It is understood that<unk>  fissure is the result of either<unk>  trauma (by constipation/diarrhea), perfusion defects with ischemia caused due to increased<unk>  pressures and decreased blood flow or increased<unk>  sphincter tone. In 90% of the patients,<unk>  fissures are found in posterior midline. A small tear is seen that extends from dentate line to<unk>  verge due to ischemia/poor perfusion of the area by inferior rectal artery (during increased sphincter tone).
Anal fissure pathophysiology
Anal fistula pathophysiology
Stomatitis pathophysiology
Anal fissure laboratory findings
Anal dysplasia
Anal fissure causes
Volvulus pathophysiology
Stomach cancer pathophysiology