<unk>  is a global health issue and is estimated to cause approximately 93.8 million cases of gastroenteritis each year. There are major limitations preventing assessment of the global burden of<unk> . Many regions of the world, especially those with a large proportion of the global population such as South/Southeast Asia and South America, do not have publicly available data regarding<unk>  surveillance. In the U.S., the incidence rate was approximately 2.8 cases per 100,000 persons in 2008. In Europe, the overall reported incidence rate was 39.01 per 100,000 persons in 2005. Children and the elderly have a higher rate of incidence.
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