As per the Rome IV criteria, the diagnosis of<unk><unk><unk>  is made when at least two of clinical features such as change in stool consistency, pain related to defecation and absence of warning signs such as unintentional loss of weight, age ≥50 years, recent change in<unk>  habit, hematochezia or melena i.e. evidence of overt gastrointestinal bleeding are positive in association with abdominal pain for  ≥1 day per week, in the previous 3 months with an onset of ≥6 months. The definition of IBS according to Rome IV, is recurrent abdominal pain associated with a change in frequency and/or form of the stool. It considers IBS as a disorder of gut–brain interaction as opposed to being a functional disorder of the GI tract. The term “abdominal discomfort” mentioned in Rome  Ⅲ, has been removed in Rome IV to avoid ambiguity. In addition to this, the frequency of abdominal pain has been changed from at least 3 days a month in the preceding 3 months (Rome III) to at least one day per week in the preceding 3 months (Rome IV).  The phrase ‘improvement of abdominal pain with defecation’ in Rome III has been changed to“abdominal pain related to defecation” in the Rome  IV criteria, as some IBS patients may report worsening of pain following defecation. Experts state that physicians should limit evaluation to Rome criteria fulfillment, if no alarm symptoms are present.
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