<unk>  is an immunomodulatory drug that is FDA approved for the prophylaxis of organ rejection in renal transplantation. There is a Black Box Warning for this drug as shown here.  Common adverse reactions include lymphedema, pericardial effusion, hepatotoxicity, hypersensitivity, tuberculosis, interstitial lung disease, exfoliative dermatitis, nephrotic syndrome.
Sirolimus
Tacrolimus 
Temsirolimus
Pimecrolimus
Cyclosporine 
Rituximab
Tofacitinib
Adalimumab