<unk><unk>  (ds)<unk><unk>  are a diverse group of<unk>  that vary widely in host range (humans, animals, plants, fungi, and bacteria), genome segment number (one to twelve), and virion organization (T-number, capsid layers, or turrets). Members of this group include the rotaviruses, renowned globally as the commonest cause of gastroenteritis in young children, and bluetongue virus, an economically important pathogen of cattle and sheep.<unk>  with dsRNA genomes are currently grouped into six families: Reoviridae, Birnaviridae, Totiviridae, Partitiviridae, Hypoviridae, and Cystoviridae. Of these six families, the Reoviridae is the largest and most diverse in terms of host range.
In recent years, remarkable progress has been made in determining, at atomic and subnanometric levels, the structures of a number of key viral proteins and of the virion capsids of several dsRNA<unk> , highlighting the significant parallels in the structure and replicative processes of many of these<unk> . By providing unique insights into fundamental aspects of structure-function relationships in virus particles, virus particle assembly, virus-cell interactions, and viral pathogenesis, approaches for the development of novel antiviral strategies and/or agents can be designed.
Double-stranded RNA viruses
Aerobic organism
Gram-negative bacteria
Viral vector
Vector
Vector 
Helper dependent virus
Gram-negative