<unk>  is a glucocorticoid for systemic use.
Substitution at position 16 also leads to more potent corticosteroids. The additional steric bulk introduced by such substituents adjacent to the dihydroxyacetone side chain also protects that moiety against metabolic degradation.
Prednylidene
Deanol
Avacopan
Diphenhydramine 
Dolastetron 
Dihydroergotamine 
Procyclidine hydrochloride
Crotamiton