<unk>  (MDM) or "mal de<unk> ", also called Mljet disease, keratosis palmoplantaris and transgradiens of siemens, (also known as "Acral keratoderma," "Mutilating palmoplantar keratoderma of the Gamborg-Nielsen type," "Palmoplantar ectodermal dysplasia type VIII",:508 and "Palmoplantar keratoderma of the Norrbotten type") is an extremely rare autosomal recessive congenital skin disorder in which dry, thick patches of skin develop on the soles of the hands and feet, a condition known as palmoplantar hyperkeratosis.:214
Meleda Disease
Borna disease
Guam disease
Haff disease
Chalicosis
Kimura disease
Tangier disease
Fuchs' dystrophy