<unk>  accounts for about 5% of cancers of the female genital system in the United States. The<unk> is the area immediately external to the vagina, including the mons pubis, labia, clitoris, bartholin glands, and perineum. The labia majora are the most common site of<unk>  carcinoma involvement and account for about 50% of cases. The labia minora account for 15% to 20% of<unk>  carcinoma cases. The clitoris and Bartholin glands are less frequently involved. Lesions are multifocal in about 5% of cases. About 90% of<unk>  carcinomas are squamous cell cancers. The<unk>  intraepithelial neoplasias (VIN), may be precursors to invasive squamous cell cancers. Common risk factors in the development of<unk>  are human papilloma virus, human immunodeficiency virus,<unk>  intraepithelial neoplasia, and lichen sclerosus.<unk>  may be classified according to histology into 3 groups:<unk>  carcinoma,<unk>  sarcoma, and<unk>  malignant melanoma. If left untreated, patients with<unk>  may progress to develop ulcer on<unk> or wart-like patches on<unk>  and chronic pruritus of the<unk>  Common complications of<unk>  include fistula and metastasis. Prognosis is generally good, and the 5 year survival rate of patients with<unk>  is approximately 71.2%. Common physical examination findings of<unk>  include<unk>  ulcers, mass, and inguinal lymphadenopathy.<unk>  biopsy is the confirmatory test for the diagnosis of<unk>  or precancerous lesions.The optimal therapy for<unk>  depends on the stage at diagnosis.The feasibility of surgery depends on the stage of<unk>  at diagnosis.
Vulvar cancer
Genital ulcer
Anal cancer
Carcinoma of the penis
Genital ulcer disease
Genital warts
Anal fissure
Angina bullosa haemorrhagica