<unk><unk><unk>  <unk> , cachexin or cachectin and formally known as<unk>  is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction.<unk> auses apoptotic cell death, cellular proliferation, differentiation, inflammation,<unk> igenesis, and viral replication.<unk> 's primary role is in the regulation of immune cells.
Dysregulation and, in particular, overproduction of<unk> ave been implicated in a variety of human diseases, as well as cancer.
Tumor necrosis factor-alpha
Interferon-gamma
Thromboxane
Leukotriene
Interleukin 13
Nitric oxide
Interleukin 27
TGF beta