<unk>  pneumonia is a common pneumonia among patients with risk factors including neurologic diseases. Microaspiration and macroaspiration of different materials are the primary cause of<unk>  pneumonia. The mechanism behind damage of lung due to<unk>  depends on the content of aspirate and the response of lung tissue to the content. Host factors including mucociliary clearance, cough reflex, and immune system might be  impaired. Chemical pneumonitis usually occurs following<unk>  of materials that are toxic to pulmonary tissue. There might be no bacterial or viral organisms involved. It is mostly associated with<unk>  of gastric acid. In case of oropharyngeal secretions the damage is due to bacteria infecting and inducing inflammation in lung tissues. Foreign body<unk>  might present acutely with mechanical obstruction or chemical pneumonitis. Lipoid pneumonia is caused by<unk>  of mineral oil when used for constipation treatment. Following oil<unk>  there is an inflammatory response with regional edema, acute cough, fever, and dyspnea. Patients with genetic syndromes and paralysis of lower cranial nerves might be prone to<unk>  pneumonia. On gross pathology, different aspirated particles might be seen. On microscopic histopathological analysis, aspirated material fragments, inflammation, fibrosis, and skeletal muscle fibers might be seen.
Aspiration pneumonia pathophysiology
Community-acquired pneumonia pathophysiology
Lipoid pneumonia pathophysiology
Air embolism pathophysiology
Aspiration pneumonia risk factors
Lipoid pneumonia causes
Community-acquired pneumonia risk factors
Lung abscess risk factors