There can be damaging physiologic effects of ingestion, inhalation, or other exposure to a broad range of chemicals, including pesticides, heavy metals, gases/vapors, drugs, and a variety of common household substances, such as bleach and ammonia. The term drug<unk>  (or simply<unk>  describes the ingestion or application of a drug or other substance in quantities greater than are recommended, routinely prescribed, or have been researched. An<unk>  is generally considered harmful and dangerous as it can result in significant morbidity (permanent injury and/or disability) and mortality (death). Narcotic and stimulant use and misuse appear to be driving the increase in poisoning deaths. Alcohol and other drugs of abuse (methamphetamine, oxycodone, etc) are also important public health issues with enormous impacts on many types of injury and violence.
Overdose
Off-label use
Designer drug
Lethal dose
Envenomation
Complication 
Blast injury
Mixture