<unk>  is the association between familial adenomatous polyposis and brain tumors like medulloblastoma, malignant glioma. It was first reported by Canadian surgeon Jacques<unk>  (1914- ) et al in 1959 and hence carries the first author's name.
The genetic basis of<unk>  is uncertain.The gene most likely to be involved is APC gene in chromosome 5q.
However, the<unk>  has been claimed to be linked to various mutations in a number of genes. For example, the mismatch repair genes MLH1 (Online Mendelian Inheritance in Man (OMIM) 120436) or PMS2 (Online Mendelian Inheritance in Man (OMIM) 600259).
Turcot syndrome
Laron syndrome
Fox-Fordyce disease
Braun-Bayer syndrome
Jervell and Lange-Nielsen syndrome
Sturge-Weber syndrome
Treacher Collins syndrome
Cruveilhier-Baumgarten syndrome