Body temperatures above 40°C (104 °F) are life-threatening. This compares to normal body temperature of 36-37°C (97-98°F). At 41°C (106 °F), brain death begins, and at 45°C (113°F) death is nearly certain. Internal temperatures above 50°C (122°F) will cause rigidity in the muscles and certain, immediate death.
Heat stroke may come on suddenly, but usually follows a less-threatening condition commonly referred to as heat exhaustion or heat prostration.
Hyperthermia pathophysiology
Hyperthermia causes
Sepsis risk factors
Diabetic ketoacidosis pathophysiology
Hyperthermia risk factors
Sepsis pathophysiology
Cardiogenic shock causes
Heat stroke risk factors