Pregnancy Rating: B
Lactation risk: Infant risk cannot be ruled out
Renal dosing: No adjustment for DVT/PE treatment. Afib: 2.5mg BID if creatinine >1.5
Hepatic dosing: No adjustment for mild impairment. Not recommended if severe impairment.
Decrease dose if concomitant use of CYP3A4 and P-gp efflux dual inhibitors
Apixaban
Enoxaparin
Rivaroxaban
Ticlopidine
Eptifibatide
Ticagrelor
Clopidogrel
Warfarin