Fresh<unk>  (FWB) has been used extensively to resuscitate casualties in military conflicts since World War I.
FWB has been shown in retrospective studies to improve early and late survival as compared to stored component therapy.
FWB has also shown to have benefit over component therapy when used in resuscitation of bleeding patients who are anticipated to have need of massive transfusions
FWB is reemerging as important tool used in modern military medicine although military physicians and providers often do not have extensive training in its proper use.
FWB is not extensively used in civilian settings due to the availability of fractionated products which were developed to meet demand for a large-scale system needed to collect and distribute blood. Using fractionated products allows for prolonged storage and improved resource utilization of donated blood.
Whole blood
Packed red blood cells
Dextrose
Fresh frozen plasma
Blood products
Methylene blue
Glucagon
N-Acetylcysteine