Occurs 2 to 6 hours after treatment started; symptoms can last for 24 hours
Malaise
Fever
Rigors
Flushing (due to vasodilation)
Hypotension
Tachycardia
Tachycardia and hyperventilation are accompanied by hypertension, and then by a drop in blood pressure due to vasodilation and declining peripheral pulse.
Tachycardia and hyperventilation are accompanied by hypertension, and then by a drop in blood pressure due to vasodilation and declining peripheral pulse.
Jarisch-Herxheimer reaction
Sepsis
Drug rash with eosinophilia and systemic symptoms syndrome
Drug rash
Staphylococcal scalded skin syndrome
Sweet's syndrome
Stevens-Johnson syndrome and toxic epidermal necrolysis
Contact dermatitis