Severe infections should be treated with immediate antibiotics and ICU admission
May require aggressive surgical debridement
Doxycycline 100 mg IV or PO BID + ceftazidime 2g IV q8h
S susceptible/sensitive (usually)
I intermediate (variably susceptible/resistant)
R resistant (or not effective clinically)
S+ synergistic with cell wall antibiotics
U sensitive for UTI only (non systemic infection)
X1 no data
X2 active in vitro, but not used clinically
X3 active in vitro, but not clinically effective for Group A strep pharyngitis or infections due to E. faecalis
X4 active in vitro, but not clinically effective for strep pneumonia
Vibrio vulnificus
Cellulitis
Vibrio parahemolyticus
Hand cellulitis
Bacillus cereus
Facial cellulitis
Bacteroides fragilis
Orbital cellulitis