Neuromuscular weakness
Upper motor neuron:
CVA
Hemorrhagic stroke
Multiple sclerosis
Amyotrophic Lateral Sclerosis (ALS) (UMN & LMN)
Lower motor neuron:
Spinal and bulbar muscular atrophy (Kennedy's syndrome)
Spinal cord disease:
Infection (Epidural abscess)
Infarction/ischemia
Trauma (Spinal Cord Syndromes)
Inflammation (Transverse Myelitis)
Acute flaccid myelitis
Degenerative (Spinal muscular atrophy)
Tumor
Peripheral nerve disease:
Guillain-Barre syndrome
Toxins (Ciguatera)
Tick<unk> 
Diabetic peripheral neuropathy
NMJ disease:
Myasthenia gravis crisis
Botulism
Organophosphate toxicity
Lambert-Eaton myasthenic syndrome
Muscle disease:
Rhabdomyolysis
Dermatomyositis
Polymyositis
Alcoholic myopathy
Non-neuromuscular weakness
Can't miss diagnoses:
ACS
Arrhythmia/Syncope
Severe infection/Sepsis
Hypoglycemia
Periodic<unk>  (electrolyte disturbance, K, Mg, Ca)<unk> 
Thyrotoxic periodic<unk> 
Respiratory failure
Emergent Diagnoses:
Symptomatic Anemia
Severe dehydration
Hypothyroidism
Polypharmacy
Malignancy
Other causes of weakness and<unk> 
Acute intermittent porphyria (ascending weakness)
Upper motor neuron:
CVA
Hemorrhagic stroke
Multiple sclerosis
Amyotrophic Lateral Sclerosis (ALS) (UMN & LMN)
Lower motor neuron:
Spinal and bulbar muscular atrophy (Kennedy's syndrome)
Spinal cord disease:
Infection (Epidural abscess)
Infarction/ischemia
Trauma (Spinal Cord Syndromes)
Inflammation (Transverse Myelitis)
Acute flaccid myelitis
Degenerative (Spinal muscular atrophy)
Tumor
Peripheral nerve disease:
Guillain-Barre syndrome
Toxins (Ciguatera)
Tick<unk> 
Diabetic peripheral neuropathy
NMJ disease:
Myasthenia gravis crisis
Botulism
Organophosphate toxicity
Lambert-Eaton myasthenic syndrome
Muscle disease:
Rhabdomyolysis
Dermatomyositis
Polymyositis
Alcoholic myopathy
CVA
Hemorrhagic stroke
Multiple sclerosis
Amyotrophic Lateral Sclerosis (ALS) (UMN & LMN)
Spinal and bulbar muscular atrophy (Kennedy's syndrome)
Infection (Epidural abscess)
Infarction/ischemia
Trauma (Spinal Cord Syndromes)
Inflammation (Transverse Myelitis)
Acute flaccid myelitis
Degenerative (Spinal muscular atrophy)
Tumor
Acute flaccid myelitis
Guillain-Barre syndrome
Toxins (Ciguatera)
Tick<unk> 
Diabetic peripheral neuropathy
Myasthenia gravis crisis
Botulism
Organophosphate toxicity
Lambert-Eaton myasthenic syndrome
Rhabdomyolysis
Dermatomyositis
Polymyositis
Alcoholic myopathy
Can't miss diagnoses:
ACS
Arrhythmia/Syncope
Severe infection/Sepsis
Hypoglycemia
Periodic<unk>  (electrolyte disturbance, K, Mg, Ca)<unk> 
Thyrotoxic periodic<unk> 
Respiratory failure
Emergent Diagnoses:
Symptomatic Anemia
Severe dehydration
Hypothyroidism
Polypharmacy
Malignancy
Other causes of weakness and<unk> 
Acute intermittent porphyria (ascending weakness)
ACS
Arrhythmia/Syncope
Severe infection/Sepsis
Hypoglycemia
Periodic<unk>  (electrolyte disturbance, K, Mg, Ca)<unk> 
Thyrotoxic periodic<unk> 
Respiratory failure<unk> 
Thyrotoxic periodic<unk> 
Symptomatic Anemia
Severe dehydration
Hypothyroidism
Polypharmacy
Malignancy
Acute intermittent porphyria (ascending weakness)
Hypokalemic periodic paralysis
Neuromuscular weakness
Thyrotoxic periodic paralysis
Upper motor neuron:
Tianeptine toxicity
CVA
Yohimbine toxicity
Hemorrhagic stroke