EN
En or EN may refer to:

Businesses
Bouygues (stock symbol EN)
Island Rail Corridor, formerly known as the Esquimalt and Nanaimo Railway (reporting mark EN)
Euronews, a news television and internet channel

Language and writing
En or N, the 14th letter of the Roman alphabet
EN (cuneiform), the mark in Sumerian cuneiform script for a High Priest or Priestess meaning "lord" or "priest"
En (Cyrillic) (Н, н), a letter of the Cyrillic alphabet, equivalent to the Roman letter "n"
En (digraph), ‹en› used as a phoneme
En (typography), a unit of width in typography
en dash, a dash one en long
En language, a language spoken in northern Vietnam
English language (ISO 639-1 language code en)

Organisations
Eastern National, a US organization providing educational products to National Park visitors
English Nature, a former UK government conservation agency
Envirolink Northwest, an environmental organization in England

Religion
En (deity) in Albanian mythology

Science and technology
Engineer
En (Lie algebra), a family of En Lie algebras, unique for 70n=5..8
EN standards, European technical standards
Electroless nickel plating, a chemical technique
Electronegativity, chemical tendency to attract electrons
Engrailed (gene), a gene involved in early embryological development
Erythema nodosum, an inflammation of the fat cells under the skin
Ethylenediamine, C2H8N2, an organic compound
Exanewton (EN), an SI unit of force: 1018 newtons
Endangered species, a conservation status level

Other uses
EuroNight, the European night train designation
Yen, Japanese currency unit, pronounced en
Empty net goal in ice hockey
Enrolled Nurse, an Australian term for a licensed practical nurse
English Wikipedia
Air Dolomiti, IATA Code of Italian regional airline
En Esch (born 1968), stage name for German musician Nicklaus Schandelmaier
"EN", a song by Arca