Sure
Sure may refer to:

Seemingly unrelated regressions
Series of Unsurprising Results in Economics (SURE), an economics academic journal
Sure, as probability, see certainty
Sure (brand), a brand of antiperspirant deodorant
Sure (company), a telecommunications company operating in British Crown Dependencies and Overseas Territories
Stein's unbiased risk estimate (SURE), in estimation theory
The river Sauer

In music
"Sure" (Every Little Thing song), from the album Eternity
"Sure" (Take That song), from the album Nobody Else

See also
Shure