41. Simon RM, Steinberg SM, Hamilton M, Hildesheim A, Khleif S, Kwak LW, Mackall CL, Schlom J, Topalian SL, Berzofsky JA: Clinical trial designs for the early clinical development of therapeutic cancer vaccines. J Clin Oncol 2001, 19(6):1848-1854. 82 Short Title: Enzalutamide Vaccine in mCRPC Version Date: 03/29/2022 15 APPENDIX A: PERFORMANCE STATUS CRITERIA ECOG Performance Status Scale Karnofsky Performance Scale Grade Descriptions Percent Description 100Normal, no complaints, no evidence of disease. 0Normal activity.