If year < year of first dose, then set month and day to December 31. If year > year of first dose, then set month and day to January 1. If year and day are present and month is missing: If year = year of first dose, then set month to month of first dose. If year < year of first dose, then set month to December. If year > year of first dose, then set month to January. If month and year are present and day is missing: If year=year of first dose and if month = month of first dose, then set day to day of first dose if month < month of first dose, then set day to last day of month if month > month of first dose, then set day to first day of month if year < year of first dose, then set day to last day of month if year > year of first dose, then set day to first day of month F or all other cases, set onset date to date of first dose Concomitant Medications Start Date: If start date is completely missing and end date is not before first dose, then the medication will be classified as both prior and concomitant. Else if start date is completely missing and end date is before first dose, then the medication will be classified as prior. I f (year is present an d month and day are missing) or (year and day are present and month is missing), then set month and day to January 1. If year and month are present and day is missing, then set day to first day of month. E nd Date: If end date is completely missing and start date is not after first dose, then the medication will be classified as both prior and concomitant. Else if end date is completely missing and start date is after first dose, then the medication will be classified as concomitant. I f (year is present and month and day are missing) or (year and day are present and month is missing), then set month and day to December 31. If year and month are present and day is missing, then set day to last day of the month. N ote that if both start and end dates are mis sing, then the medication will be classified as prior and concomitant. Bavarian Nordic, Inc. Statistical Analysis Plan Amendment 1 Protocol: BNIT -PRV -301 Date Issued: 29 June 2015 C onfidential 33 Revised: June 2015 17.Appendix D: List of Tables, Listings, and Figures