and K.S.; software, S.D. and K.S.; validation, K.S.; formal analysis, K.S.; investigation, K.S.; resources, S.D.; data curation, K.S.; writing—orig inal draft preparation, S.D. and K.S.; writing—review and editing, S.D. and K.S.; visu- alization, K.S.; supervision, S.D.; project administration, S.D.; funding acquisition, S.D. All authors have read and agreed to the published version of the manuscript. Funding: This research received no external funding. Institutional Review Board Statement: Not applicable. Informed Consent Statement: Not applicable. Data Availability Statement: All the data supporting reported results can be found in the Supplementary Materials. Acknowledgments: The author, S.D. (Sivanesan Dakshanamurthy), acknowledges partial support from the Georgetown University Lombardi Comprehensive Cancer Center (LCCC) Cancer Cell Biology Program Pilot Award. The author K.S. (Kush Savsani) participated in the Lombardi Compre- hensive Cancer Center, Summer Research Program. Diseases 2024 ,12, 149 13 of 14 Conflicts of Interest: The authors declare no conflict of interest. References 1. Shemesh, C.S.; Hsu, J.C.; Hosseini, I.; Shen, B.Q.; Rotte, A.; Twomey, P .; Girish, S.; Wu, B. Personalized Cancer Vaccines: Clinical Landscape, Challenges, and Opportunities. Mol. Ther. J. Am. Soc. Gene Tssher 2021 ,29, 555–570. [CrossRef] [PubMed] 2. Sahin, U.; Türeci, Ö. Personalized vaccines for cancer immunotherapy. Science 2018 ,359, 1355–1360. [CrossRef] [PubMed] 3. Rojas, L.A.; Sethna, Z.; Soares, K.C.; Olcese, C.; Pang, N.; Patterson, E.; Lihm, J.; Ceglia, N.; Guasp, P .; Chu, A.; et al. Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer. Nature 2023 ,618, 144–150.