2014;371(17):1609-18. Treos Bio ZRT OBERTO -101 Amendment 3 Product: PolyPEPI 1018 Colorectal Cancer Vaccine Page 77 of 81 CONFIDENTIAL Mansfield AS, Nevala WK, Lieser EAT, et al. The immunomodulatory effects of bevacizumab on systemic immunity in patients with metastatic melanoma. Oncoimmunology.