20. Formenti SC, Lee P, Adams S, Goldberg JD, Li X, Xie MW, Ratikan JA, Felix C, Hwang L, Faull KF et al : Focal Irradiation and Systemic TGFbeta Blockade in Metastatic Breast Cancer. Clin Cancer Res 2018, 24(11):2493-2504. 21. Ivanovic V, Melman A, Davis- Joseph B, Valcic M, Geliebter J: Elevated plasma levels of TGF -beta 1 in patients with invasive prostate cancer . Nat Med 1995, 1(4):282-284.