• Active infection requiring treatment or an unexplained febrile (> 101.5o F) illness. Re-MATC H Protocol Page 24 of 106 Version: 20180628 • Known immunosuppressive disease , human immunodeficiency virus infection , or carriers of Hepatitis B or Hepatitis C virus . • Patients with active renal, cardiac (congestive cardiac failure, myocardial infarction, myocarditis), or pulmonary disease.