16 Figure 11. Lymphocyte counts of patients with newly -diagnosed GBM receiving standard dose adjuvant TMZ (200 mg/m2/5d) and dose- intensified TMZ (100 mg/m2/21d). ...................................................... 17 Figure 12. Antibody titers in patients during standard- dose TMZ (200 mg/m2/5d) and dose- intensified TMZ (100 mg/m2/21d). ..................................................................................................................................