The Principal Investigator is responsible for ensuring this. 5.9.2 Laboratory safety measurements and variables 5.9.2.1 Methods of assessment Routine haematology, biochemistry and urinalysis assessments will be performed at the laboratory local to the trial centre. The following routine laboratory parameters will be investigated (see section 9.7 for the total volume of blood samples to be collected): Table 5: Summary of required laboratory assessments Chemistry Haematolog y Clotting Screen Urinalysis Alkaline Phosphate Red blood cell (RBC) count INR Blood ALT (SGPT) Haemoglobin Proteins AST (SGOT) Haematocrit Glucose Total Protein White blood cell (WBC) count White cells Albumin Neutrophils Bilirubin Lymphocytes Lactate dehydrogenase (LDH) Monocytes Blood urea nitrogen (BUN) or Uric Acid Eosinophils Creatinine Basophils Sodium Platelet count Potassium Creatinine kinase (CK) CT TG01 -01 Version v 10.0 27 June 2018 Confidential 68 / 87 5.9.2.2 Calculation or derivation of endpoint Section 7 provides details on how AEs based on laboratory tests will be recorded and reported. Laboratory test results will be graded according to NCI-CTC version 4.0.