e15507 Publication Only A study on classifying tumor neoantigens to enhance the accuracy of liquid biopsy in CRC cancer. Fenghua Guo, Wenting Liao, Jun Li, Yaru Chen; HaploX Biotechnology, Shenzhen, China Background: Personalized neoantigen vaccines are a promising therapeutic approach in co- lorectal cancer (CRC). These vaccines are designed based on the identification of specific gene mutations, aiming to evoke an immune response.