If such adverse reactions occur, subsequent infusions should be administered over the shortest period, not less than 60 minutes, that is well tolerated. Subjects must be observed for at least 30 minutes after the infusion. No corticosteroids are to be used for the management of common infusion related AEs. Subjects shoul d receive full supportive care, including transfusions of blood and blood products, antibiotics, antiemetics, etc., when appropriate. 5.5 Additional Studies Please see Section 9.0 for the description of correlative studies 6.0 Dose Delays/Modifications for Adverse Events This study will use Common Terminology Criteria for Adverse Events v 4, which can be found at the CTEP, website: http://ctep.cancer.gov/reporting/ctc.html Management of Anticipated Toxicities: Missed doses of radiation therapy and Sipuleucel -T will not be made up. Treatment should be stopped for any protocol treatment related Grade 3 toxicity or greater that cannot be controlled with good medical practice intervention.