20. LABORATORY EVALUATIO NS 20.1 Baseline and Eligibility To be enrolled, patients must be scheduled for definitive resection, biopsy, and/or cytology collection of reMB/PNET or, in select cases, be at an outside institution and have had surgical resection and tumor tissue snap frozen and available for TTRNA. Clinical and laboratory evaluations will be obtained within 2 weeks of enrollment for the purposes of meeting Inclusion and Exclusion Criteria as outlined above . Final pathologic diagnosis of reMB/PNET will be made by the study pathologist, or by certified outside pathology report . Pathology slides consisting of 1 hematoxylin and eosin (H&E 44) and 19 unstained slides for immunohistochemistry prepared on Fischer Plus glass or Histostix coated slides when available will be delivered to: Duane Mitchell, M.D., Ph.D. Department of Neurosurgery 1149 Newell Drive , Room L1- 151 University of Florida Gainesville, Florida 32611 Blood will also be sent for the following tests: C BC ( Complete Blood Count) with manual differential. Initial clinical evaluations will also include a complete physical and neurologic examination . A baseline brain and spine MRI and study eligibility MRI (with and without gadolinium enhancement taken post -surgical resection of recurrent disease) of the brain using standard 5 mm slices with 2.5 mm spacing for comparison to subsequent MRI images will also be obtained. 20.2 Data and Spec imens to be Accessioned Before undergoing surgical resection Re-MATC H Protocol Page 80 of 106 Version: 20180628 - History and physical examination - CBC, PT, PTT, Comprehensive metabolic panel & Type and Screen if clinically indicated - Material in excess of that required for pathologic diagnosis will be transported to Dr.