For parts B1 and C1, Cycle 2 Day 2 only and Cycle 2 Day 8 o nly, assessments should take place on Cycle 4 Day 2 and Cycle 4 Day 8. CBC with Differential and PlateletsX X X X X X XXXShould also be collected at each time point where samples are collected For parts B1 and C1, Cycle 2 Day 2 only and Cycle 2 Day 8 only assessmen ts should take place on Cycle 4 Day 2 and Cycle 4 Day 8. Thyroid Function Tests XX (see notes)To include TSH with reflex testing (free T3 and free T4), if applicable. Results should be examined by th e investigator or appropriate designee within 48 hours of dose administration.