2010. HPV -induced oropharyngeal cancer, immune response and response to therapy. Cancer Lett 288, 149 -155. 48. Smeets SJ , Hesselink AT , Speel EJ , Haesevoets A, Snijders PJ , Pawlita M , Meijer CJ , Braakhuis BJ , Leemans CR , Brakenhoff RH . 2007. A novel algorithm for reliable detection of human papillomavirus in paraffin embedded head and neck cancer specimen. Int J Cancer. 121(11):2465 -72. 49. Kenter, et al. 2009 Vaccination against HPV -16 oncoproteins for vulvar intraepithelial neoplasia. NEJM 361:1838- 1847 50. Genden et al. 2011 Transoral robotic resection and reconstruction for head and neck cancer. Laryngoscope . 121(8): 1668 -74. 51. Eisenhauer et al. 2009 New response evaluation criteria in solid tumors: revised RECIST guideline (version1.1). Eur J Cancer. 45(2) 228- 47. 52. Maciag, P.C., S.