flu -like symptoms, fever, or allergic reactions. (Approximately 3 mL blood per draw). k: Pre -treatment biopsy (archival tissue may be submitted if collected le ss than 6 -months prior to C1D1 and the local pathologist confirms that an adequate amount of tissue/tumor cells exist to allow completion of all testing as outlined in the Specimen Collection Manual) and on -treatment biopsy collected within 5 -14 days after patient completes 2nd dose of HS -130/HS -110 for genomic and proteomic analysis of exploratory biomarkers (e.g. mIHC).