and every 12 weeks ther eafter until off the study Page 34 of 50 IRB Protocol No. 12367 Version Date: 10/24/2017 Version: 09 c. after week 12 radiologic evaluation and tumor measurement will be done at the discretion of treating physician d. after week 12 Immune Assays will be performed at following time intervals : week 24, 36, 48, 60 e. Off study visit laboratory tests will b performed at the discretion of treating physician f. this protocol allows for flexibility of suggested timing of visits and tests : +/ - 1 week during first 8 weeks of study and +/ - 2 weeks thereafter g. Chest CT is optional.