IND NUMBER: IND SPONSOR/INVESTIGATOR PROGRAM DIRECTOR: BB-IND#14919 George E. Peoples, MD, FACS Cancer Insight, LLC 110 E. Houston Street, Floor 7 San Antonio, TX 78205 210-557-4291 georgepeoples2@hotmail.com MEDICAL MONITOR: Cancer Insight, LLC PROTOCOL VERSION/DATE: SPONSOR STUDY NUMBER: 3.1/ 05 March 2017 ML25749 CONFIDENTIAL Page 2 of 102 Protocol: HERCEPTIN® + E75/GM-CSF Version 3.1 ML25749 05 March 2017 TABLE OF CONTENTS Page 1. INTRODUCTION ............................................................................................