ID01 ID02 ID03 ID04 ID05 ID06 ID07 ID08 ID09 ID10 ID11 ID12 ID13 ID14 ID15 ID17 ID18 ID19 ID20 ID21 ID22 ID23 ID24 ID25 ID26 ID27 ID28 ID29 ID30 ID31 ID32 ID33Location Gender Meth. classWHOAge Therapy Location Location Location Female MaleGender 18–303 1–44 45–65Age 4 3WHOTMZc TMZ XRTTherapy High LowMeth. class NDSubtotal Complete BiopsyResectionResection Gender Meth. classWHOAge Therapy Resection Gender Meth. classWHOAge Therapy Resection Gender Meth. classWHOAge Therapy Resection Fig. 1 | Patient characteristics at baseline and SOC treatment. cTMZ, concomitant TMZ (75 mg m−2 body surface area (BSA)) daily during radiotherapy; TMZ, monotherapy with TMZ (three cycles); XRT, radiotherapy (30 × 2 Gy, if not specified otherwise in Supplementary Table 3); Low, low grade methylation (Meth.) class; High, high grade methylation class; ND, not determined; WHO, WHO grade of tumour. n = 32 patients.