15 Engelhard VH, et al. J Immunother Cancer 2020;8:e000262. doi:10.1136/jitc-2019-000262Open access 17 Slingluff CL, Petroni GR, Chianese- Bullock KA, et al. Randomized multicenter trial of the effects of melanoma- associated helper peptides and cyclophosphamide on the immunogenicity of a multipeptide melanoma vaccine. J Clin Oncol 2011;29:2924–32. 18 Slingluff CL, Lee S, Zhao F , et al. A randomized phase II trial of multiepitope vaccination with melanoma peptides for cytotoxic T cells and helper T cells for patients with metastatic melanoma (E1602). Clin Cancer Res 2013;19:4228–38.