144 | Nature | Vol 618 | 1 June 2023 ArticlePersonalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer Luis A. Rojas1,2,18, Zachary Sethna1,2,18, Kevin C. Soares2,3, Cristina Olcese2, Nan Pang2, Erin Patterson2, Jayon Lihm4, Nicholas Ceglia4, Pablo Guasp1,2, Alexander Chu4, Rebecca Yu1,2, Adrienne Kaya Chandra1,2, Theresa Waters1,2, Jennifer Ruan1,2, Masataka Amisaki1,2, Abderezak Zebboudj1,2, Zagaa Odgerel1,2, George Payne1,2, Evelyna Derhovanessian5, Felicitas Müller5, Ina Rhee6, Mahesh Yadav6, Anton Dobrin7,8, Michel Sadelain7,8, Marta Łuksza9, Noah Cohen10, Laura Tang11, Olca Basturk11, Mithat Gönen12, Seth Katz13, Richard Kinh Do13, Andrew S. Epstein14, Parisa Momtaz14, Wungki Park3,14, Ryan Sugarman14, Anna M. Varghese14, Elizabeth Won14, Avni Desai14, Alice C. Wei2,3, Michael I. D’ Angelica2,3, T . Peter Kingham2,3, Ira Mellman6, Taha Merghoub15, Jedd D. Wolchok15, Ugur Sahin5, Özlem Türeci5,16, Benjamin D. Greenbaum4,17 ✉, William R. Jarnagin2,3, Jeffrey Drebin2,3, Eileen M.