Patients with kidney failure or other kidney problems should notify their physician.  Nasopharyngo-laryngoscopy This procedure takes only a few minutes, is painless and does not require any sedation. It is a normal part of an ENT exam. 70 Abbreviated Title: Neoadjuvant IO for HNSCC Version Date: August 31, 2022 Risks due to Radiation The study will involve radiation from the following sources: Up to 3 CT scans (Neck and Chest) per year for disease assessment Subjects in this study may be exposed to approximately 0.99 rem. The CT scans exposes to 3.3 years of background radiation.