(2018). Philentropy: Information Theory and Distance Quanti- ﬁcation with R. J. Open Source Softw. 3, 765 . 37.Warnes, G.R., Bolker, B., Bonebakker, L., Gentleman, R., Liaw, W.H.A., Lumley, T., Maechler, M., Magnusson, A., Moeller, S., Schwartz, M.,et al. (2015). gplots: Various R Programming Tools for Plotting Data . 8Cell Reports Medicine 1, 100141, November 17, 2020Reportll OPEN ACCESS 38.R Core Team (2018). R: A Language and Environment for Statistical Computing (R Foundation for Statistical Computing) . 39.Therneau, T.M., and Grambsch, P.M.