This is regardless of whether the AE start time shows the AE started before the dose that day. The only exception is for the first vaccination ; if ‘Did AE occur prior to first dose’ is checked then no vaccination number will be assigned. Duration of treatment : this is from the day of the first vaccination until the day of the final vaccination . Duration of treatment will be described using summary statistics. Completed vaccination : AST-VAC2 vaccinations are to be given once a week for 6 weeks. A patient is considered to have completed vaccination when vaccination data entered is for each of those expected weekly visits (despite dose modifications) . Treated patients: If the drug administration form in the eCRF has the ‘date of vaccination ’ completed, this constitutes a treated patient. 5.11 Decimal places When data are used in calculations it important that rounding is only conducted when the final test result is obtained (to avoid accumulation of errors).