Laboratory Disease Evaluation:  Quantitative serum immunoglobulin levels.  Serum protein electrophoresis (SPEP).  24-hour urine collection to determine creatinine clearance and protein excretion, urine electrophoresis (UPEP) required for participants with +UPEP at baseline. Otherwise, random UPEP is permitted. If the random UPEP is positive, a 24-hour urine collection is required.  Immunofixation of urine and serum protein regardless of SPEP and UPEP results. 5.11.3 Toxicity Assessment Visit (+/- 7 days) Participants taken off treatment due to disease progression or to start alternative anti-myeloma therapy at MD discretion will be required to do a toxicity assessment visit 30 days after the last dose of study treatment. 1.