2 Marita Teng, M .D. 2 Krzysztof Misiukiewicz, M.D. 2 At BCM: Vlad Sandulache, M.D. ,Ph.D1 Donald Donovan M.D .1 Andrew Huang, M.D.1 Nelson Liou, M. D. 1 Jun Zhang, M.D. 1 Scientific Collaborators: At ISMMS: Seunghee Kim -Schulze, PhD .2 Michael Donovan, M.D. 2 Nina Bhardwaj, M.D./PhD. 2 Sacha Gnjatic, PhD . 2 David Zhang, M.D.