.................. 12 1.1 STUDY OBJECTIVES AND ENDPOINTS ................................ ................................ .................. 12 1.1.1 Primary Objectives ................................ ................................ ................................ .....12 1.1.2 Secondary Objectives ................................ ................................ ................................ .12 1.1.3 Exploratory Objectives ................................ ................................ ............................... 12 1.1.4 Primary Endpoints ................................ ................................ ................................ ......12 1.1.5 Secondary Endpoints ................................ ................................ ................................ ..12 1.1.6 Exploratory Endpoints ................................ ................................