Carey LA, Dees EC, Sawyer L, et al. The triple negative paradox: Pr imary tumor chemosensitivity of breast cancer subty pes. Clin Cancer Res. 2007; 13:2329 -2334. 11. Kassam F, Enright K, Dent R, et al: Survival outcomes for patients with metastatic triple -negative breast cancer: Implications for clinical practice and trial desi gn. Clin Breast Cancer. 2009; 9:29 -33. 12. Hodi FS, O’Day SJ, McDermott DF, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med. 2010;363(8):711 -23. 13.