and Chen, H., 2008. Pr oper inference from Simon's two ‐stage designs. Statistics in Medi cine, 27(16), pp.3145-3154. 45. Brookmeyer, R., and Crowley, J. (1982), ‘‘ A Confidence Interval for the Median Survival Time,’’ Biometrics, 38, 29–41. Phase 2 Study of GVAX (with CY) and pembrolizum ab in MMR-p advanced colorectal cancer J16154/Version 5/ January 17, 2018 63APPENDIX A: Performance Status Criteria ECOG Performance Status Scale Karnofsky Performance Scale Grade Descriptions Percent Description 0 Normal activity. Fully active, able to carry on all pre-disease performance without restriction.