Autoimmune reaction 2 4 2 . . Blood/Bone Marrow 8 16 7 1 . Hemoglobin 4 8 4 . . Hemoglobin 2 4 2 . . Lymphopenia 2 4 1 1 . Cardiovascular (General) 2 4 2 . . Edema 2 4 2 . . Constitutional Symptoms 43 84 27 12 4 Constitutional symptoms, other 1 2 1 . . Fatigue (lethargy, malaise, asthenia) 42 82 27 11 4 Fever (in the absence of neutropenia) 14 27 11 3 . Rigors, chills 27 53 25 2 . Sweating (diaphoresis) 16 31 16 . . Dermatology/Skin 51 100 3 35 13 Alopecia 1 2 1 . . Bruising 1 2 1 . . Dermatology/Skin, other 4 8 3 1 . Flushing 10 20 10 .