............................... 50 7.2 NCI-IRB AND CLINICAL DIRECTOR (CD) REPORTING ................................ ....................... 50 7.2.1 NCI-IRB and CD Expedited Reporting of Unanticipated Problems and Deaths .......50 7.2.2 NCI-IRB Requirements for PI Reporting at Continuing Review ............................... 51 7.2.3 NCI-IRB Reporting of IND Safety Reports ................................ ............................... 51 7.3 IND SPONSOR REPORTING CRITERIA ................................ ................................ .................. 51 7.3.1 Reporting Pregnancy ................................ ................................ ................................ ..51 7.4 SAFETY REPORTING CRITERIA TO THE PHARMACEUTICAL COLLABORATORS ..................... 52 7.4.1 Etubics Corporation ................................ ................................