STUDY PROCEDURES AND FLOWCHART A detailed schedule of all study events can be found in Appendix 1 (Stage 1) and Appendix 2 (Stage 2). DocuSign Envelope ID: B3F56764-C440-4885-BA44-7578C4A73DB3 Stemline Therapeutics, Inc. Protocol: STML- 701-0114 Version 3.0, 10-JUL-2015 (Amendment 2) Statistical Analysis Plan Page 19 of 63 4.