Depending on your hardware, it can take some time to quantize a model from scratch. It can take ~5 minutes to quantize the facebook/opt-350m model on a free-tier Google Colab GPU, but it'll take ~4 hours to quantize a 175B parameter model on a NVIDIA A100. Before you quantize a model, it is a good idea to check the Hub if a GPTQ-quantized version of the model already exists.