In 1722, at the direction of her mother, she was inoculated against smallpox by variolation, an early type of immunisation popularised by Lady Mary Wortley Montagu and Charles Maitland.
În 1722, la indicația mamei sale s-a imunizat de variolă prin variolizare, un tip de imunizare timpuriu popularizat de Lady Mary Wortley Montagu și Charles Maitland.