Though the developers tried to make the "coolness" theme fit into the world of Resident Evil, Mikami felt it strayed too far from the series' survival horror roots and gradually convinced all of the staff members to make the game independent from it.
Iako su developeri pokušali napraviti "cool" temu u svijetu Resident Evila, Mikami je osjetio da je to previše odlutalo od korijena survival horror serijala i postepeno je uvjerio članove osoblja da stvore igru neovisnu o tome.