Apart from both titles being named after iconic Los Angeles streets, Mulholland Drive is "Lynch's unique account of what held Wilder's attention too: human putrefaction (a term Lynch used several times during his press conference at the New York Film Festival 2001) in a city of lethal illusions".
Uz to što oba naslova filma aludiraju na poznate ulice Los Angelesa, Mulholland Drive je "Lynchov jedinstveni pogled na ono što je i Wilderu privuklo pažnju: ljudsko truljenje (termin kojeg je Lynch nekoliko puta upotrijebio tijekom konferencije za novinare na filmskom festivalu u New Yorku 2001. godine) u gradu ubojitih iluzija".