Soon after PubChem's creation, the American Chemical Society lobbied U.S. Congress to restrict the operation of PubChem, which they asserted competes with their Chemical Abstracts Service.
Malo poslije nego je stvoren PubChem, Američko kemijsko društvo lobiralo je u Kongresu SAD za ograničenje djelokruga PubChem, zbog toga što su dokazivali da konkurira njihovom Chemical Abstracts Serviceu.