Its use is endorsed by the American Heart Association and the American Academy of Neurology as the recommended treatment for acute stroke within three hours of onset of symptoms as long as there are no other contraindications (such as abnormal lab values, high blood pressure, or recent surgery).
Korist trobmolize potvrđena je od strane Američke udruge za srce (American Heart Association) i Američke neurološke akademije (American Academy of Neurology) kao preporučenog tretmana za akutni moždani udar unutar tri sata od nastupa simptoma ako nisu prisutne kontraindikacije (poput abnormalnih vrijednosti laboratorijskih testova, visoki krvni tlak ili nedavni kirurški zahvati).