The intent of his invasion was to capture Rome and "reunite the Roman Empire", and, at first, looked like he might be able to do it with the easy capture of Otranto in 1480 but Otranto was retaken by Papal forces in 1481 after the death of Mehmed.
Namjera mu je bila osvojiti Rim i da "ujedini Rimsku Imperiju", i, u početku je izgledalo kao da to može uraditi lakim zauzimanjem Otranta 1480. ali je Otranto preuzela papina vojska nakon Mehmedove smrti 1481. godine.