Leighton Meester and Blake Lively–who started auditioning in December 2006–were the first two actresses to be chosen in February for the lead roles of Blair Waldorf and Serena van der Woodsen, respectively.
Blake Lively i Leighton Meester - koje su s audicijama započele još u prosincu 2006. - bile su prve dvije glumice izabrane u veljači za glavne uloge Serene van der Woodsen i Blair Waldorf.