The most widely used diagnostic criteria for CFS are the 1994 research guidelines proposed by the "International Chronic Fatigue Syndrome Study Group", led by the Centers for Disease Control and Prevention.
Najviše korišteni dijagnostički kriteriji za SKU su crte vodilje istraživanja 1994 godine koje je predložila „Internacionalna grupa proučavanja sindroma kroničnog umora“ ("International Chronic Fatigue Syndrome Study Group"), koju predvodi Centar za kontrolu i prevenciju bolesti (Centers for Disease Control and Prevention).