After decreasing dramatically with the availability of penicillin in the 1940s, rates of infection have increased since the turn of the millennium in many countries, often in combination with human immunodeficiency virus (HIV).
Nakon što se dramatično smanjila proširenost bolesti, zbog široke dostupnosti penicilina nakon 1940. godine, u novom se mileniju u mnogim zemljama učestalost povećala, često udružena sa zarazom humanim virusom imunodeficijencije (HIV).