Given the existence of the Russian-led Commonwealth of Independent States (CIS), GUAM is sometimes seen in Russia as a way of countering the Russian influence in the area and as part of a strategy backed by the United States.
S obzirom na rusko vodstvo Zajednice nezavisnih država, Rusi uglavnom gledaju na GUAM, kao način na borbu protiv ruskog utjecaja na tom području, a kao dio strategije potpomognute SAD-om.