Many people who present with secondary syphilis (40–85% of women, 20–65% of men) do not report previously having had the classical chancre of primary syphilis.
Mnogi bolesnici koji imaju simptome sekundarnog sifilisa (40–85 % žena, 20–65 % muškaraca) ne opisuju prethodnu pojavu klasičnog tvrdog vrijeda primarnog sifilisa.