Apart from not smoking, the American Cancer Society recommends keeping a healthy weight, and increasing consumption of fruits, vegetables, and whole grains, while decreasing consumption of red and processed meat, although there is no consistent evidence this will prevent or reduce pancreatic cancer specifically.
Bortset fra ikke at ryge anbefaler American Cancer Society også, at man holder en sund vægt, samt øger sit indtag af frugter, grøntsager og fuldkorn, samt spiser mindre rødt og forarbejdet kød, omend der ikke findes fast evidens for, at dette kan forhindre eller reducere bugspytkirtelkræft specifikt.