The Sarmiento Railway line served the Villa Epecuén station, while the Midland Railway and the Buenos Aires Great Southern Railway carried passengers to nearby Carhué station.
Villa Epecuén station blev betjent af Sarmiento-jernbanelinjen, mens Midland Jernbane og Buenos Aires Store Sydlige Jernbane medtog passagerer til Carhué station i nærheden.