According to the 2001 census, the region had 605,583 inhabitants, with Slovaks forming a relatively homogeneous majority (97.3%), with a small minority of Czechs (1%) and others.
Ifølge folketællingen fra 2001, havde regionen 605,583 indbyggere, hvoraf at slovakkere danner et relativt stort homogent flertal (97.3%), med et lille mindretal af tjekkere (1%) samt andre.