After the arrival of the second cholera pandemic in the United States (1832), Louisville in the 1830s and 40s gained the nickname "graveyard of the west", due to the polluted local water giving Louisville residents cholera and typhoid at epidemic levels.
Efter udbrudet af den anden kolerapandemi i USA (1832), fik Louisville i 1830'erne og 40'erne øgenavnet "graveyard of the west" (vestens kirkegård) grundet det forurenede lokale vand, der gav byens borgere kolera og tyfus på epidemisk niveau.