For neurosyphilis, due to the poor penetration of benzathine penicillin into the central nervous system, those affected are given large doses of intravenous penicillin for a minimum of 10 days.
På grund af den begrænsede penetration af penicillin G i centralnervesystemet anbefales det for personer med neurosyfilis, at de gives store doser intravenøs penicillin i mindst 10 dage.