At the Battle of Antietam, Benning's brigade was a crucial part in the defense of the Confederate right flank, guarding "Burnside's Bridge" across Antietam Creek all morning against repeated Union assaults.
I slaget ved Antietam var Bennings brigade en vigtig del af forsvaret af den konfødererede højre flanke, hvor han bevogtede "Burnside's Bridge" over Antietam Creek hele morgenen mod gentagne Unionsangreb.