Zappa died, after his long battle with prostate cancer, on December 4, 1993, 17 days before his 53rd birthday at his home with his wife and children by his side.
Zappa døde efter lang tids kamp mod prostatakræft den 4. december 1993, 18 dage før sin 53-års fødselsdag, i sit hjem med sin hustru og sine børn ved sin side.