While 11-COOH-THC does not have any psychoactive effects in its own right, it may still have a role in the analgesic and anti-inflammatory effects of cannabis, and has also been shown to moderate the effects of THC itself which may help explain the difference in subjective effects seen between occasional and regular users of cannabis.
Mens THC-COOH ikke har nogen psykoaktive virkninger, kan det stadig have en rolle i analgetiske og anti-inflammatoriske virkninger af cannabis, og har også vist sig at moderere virkningerne af THC, en form kaldet antagonisme, hvilket kan hjælpe med at forklare forskellen i subjektive virkninger, der ses mellem lejlighedsvise og regelmæssige brugere af cannabis.