The latter two disulfide bonds (40-95 and 65-72) are less essential for folding; either one can be reduced (but not both) without affecting the native structure under physiological conditions.
De sidste to svovlbroer (40-95 og 65-72) er mindre essentielle for foldningen; enten den ene eller den anden kan reduceres (blot ikke begge) uden at det påvirker den native struktur under fysiologiske betingelser.