In 1705 Graupner left Leipzig to play the harpsichord in the orchestra of the Hamburg Opera under the direction of Reinhard Keiser, alongside George Frideric Handel, then a young violinist.
I 1705 forlod Graupner Leipzig for at spille cembalo i orkesteret ved Hamborg-operaen under ledelse af Reinhard Keizer, sammen med George Frideric Handel, den gang en ung violinist.