In 1918 it was demonstrated in operations on dogs that total removal of the duodenum is compatible with life, but this was not reported in human surgery until 1935, when the American surgeon Allen Oldfather Whipple published the results of a series of three operations at Columbia Presbyterian Hospital in New York.
I 1918 blev det ved operationer på hunde demonstreret, at den fuldstændige fjernelse af tolvfingertarmen var kompatibel med fortsat liv, men dette blev ikke rapporteret ved kirurgi på mennesker før 1935, da den amerikanske kirurg Allen Oldfather Whipple udgav resultaterne af tre operationer på Columbia Presbyterian Hospital i New York.