In 1890, Hermann Sachse, a 28-year-old assistant in Berlin, published instructions for folding a piece of paper to represent two forms of cyclohexane he called symmetrical and unsymmetrical (what we would now call chair and boat).
I 1890 offentliggjorde den 28-årige assistent, Hermann Sachse, i Berlin instruktioner til at folde et stykke papir der repræsenterer to former for cyklohexan han kaldte symmetrisk og asymmetrisk (hvad vi nu ville kalde stolkonformation og bådkonformation).