D'Hoore signed with the Wiggle–Honda team for the 2015 season, winning 13 races in her first year with the team to become the most prolific winner in the women's peloton in 2015.
D'Hoore underskrev kontrakt med Wiggle-Honda holdet for 2015 sæsonen, hun vandt 13 løb i sit første år for holdet, hvor hendes hold blev det mest vindende i 2015.