Since the tight control of enzyme activity is essential for homeostasis, any malfunction (mutation, overproduction, underproduction or deletion) of a single critical enzyme can lead to a genetic disease.
Eftersom en streng kontrol af enzymaktivitet er essentiel for homøostase, kan enhver funktionsfejl (mutation, overproduckion, underproduktion eller deletion) af et enkelt kritisk enzym føre til en genetisk sygdom.