Botho Prinz zu Sayn-Wittgenstein-Hohenstein (His Serene Highness Prince Botho of Sayn-Wittgenstein-Hohenstein) (16 February 1927 in Eisenach – 27 January 2008 in Salzburg) was a German politician.
Botho Prinz zu Sayn-Wittgenstein-Hohenstein (hans højhed prins Botho til Sayn-Wittgenstein-Hohenstein) (16. februar 1927 i Eisenach - 27. januar 2008 i Salzburg) var en tysk konservativ politiker.