Data sets representing entire genomes' worth of DNA sequences, such as those produced by the Human Genome Project, are difficult to use without the annotations that identify the locations of genes and regulatory elements on each chromosome.
Datasæt, der repræsenterer hele genomers DNA-sekvenser, såsom de der er produceret af Human Genome Project, er svære at bruge uden de annoteringer, der identificerer generne og de regulerende elementers beliggenhed på hvert kromosom.