In Canada, 2C-B is classified under Controlled Drugs and Substances Act as Schedule III as "4-bromo-2,5-dimethoxybenzeneethanamine and any salt, isomer or salt of isomer thereof".
In Australien befindet sich 2C-B im Anhang B. In Kanada fällt es unter CDSA Schedule III als 4-Bromo-2,5-dimethoxybenzeneethanamine and any salt, isomer or salt of isomer thereof.