The OSF has branches in 37 countries, encompassing a group of country and regional foundations, such as the Open Society Initiative for West Africa, and the Open Society Initiative for Southern Africa; its headquarters are in New York City.
Az OSF-nek 37 országban van képviselete, beleértve olyan regionális alapítványokat mint az Open Society initiative for West Africa (Nyugat-Afrika), az Open Society initiative for Southern Africa (Dél-Afrika).