These receptors send a signal up to the brain stem, and from there, it forks off into many areas of the forebrain, one of which is the cerebral cortex.
Reseptor ini menghantar signal  kepada batang otak. Dari situ,  ia bergerak ke kawasan-kawasan lain  di otak depan, salah satu daripadanya ialah  korteks serebrum.