In Spanish, "tú" is unisex informal singular, "usted" is unisex formal singular, "vosotros" is masculine informal plural, "vosotras" is feminine informal plural, and "ustedes" is the unisex formal plural.
En español, "tú" es unisex informal singular, "usted" es singular unisex, "vosotros" es plural masculino, "vosotras" es plural femenino, y "ustedes" es plural unisex.