Yes, we can do pair-wise, A and B, A and C, A and D, but what about A, B, C, D, E, F, G all together, being taken by the same patient, perhaps interacting with each other in ways that either makes them more effective or less effective or causes side effects that are unexpected?
Sim, podemos fazer com base em pares. "A" e "B", "A" e "C", "A" e "D". Mas e "A, B, C, D, E, F, G" todos juntos, tomados pelo mesmo paciente, talvez interagindo entre si de forma que talvez os deixem mais, ou menos, eficientes; ou causem efeitos colaterais inesperados?