That's because cytokines and prostaglandin can reach even higher structures  in your brain, disrupting the activity  of neurotransmitters, like glutamate, endorphins, serotonin, and dopamine.
Isso porque as citocinas e a prostaglandina podem atingir estruturas superiores do cérebro, prejudicando a atividade de neurotransmissores, como o glutamato, as endorfinas, a serotonina, e a dopamina.