Certain diseases, growths in the thryoid or chemical imbalances in the body can confuse the organ and make it deaf  to the pituitary's guiding commands.
Hin nexweşî, wek mezinbûna tiroîd, û bê ahengîyên kîmyevî, tiroîd şaş dikin, û tiroîd ji qontrala hîpofîz derdikeve.