We think it takes at least 15 to 20 years of amyloid plaque accumulation before it reaches a tipping point, then triggering a molecular cascade that causes the clinical symptoms of the disease.
Pensamos que se tarda entre 15 e 20 anos en acumular placa amiloide antes de que alcance o punto crítico, logo desencadea un cadoiro molecular que provoca os síntomas da doenza.