Their pain receptors, called nociceptors, trigger in response, cueing the brain to release a flood  of neuropeptides that inflame the cranial blood vessels, swelling and heating up the head.
Os receptores da dor,  chamados nociceptores, actívanse ante o estímulo liberando un fluxo de neuropéptidos que inflaman os vasos craniais, causando sensación de inchazón e febre.