Background#R##N#The emergence of next-generation RNA sequencing (RNA-Seq) provides tremendous opportunities for researchers to analyze alternative splicing on a genome-wide scale. However, accurate detection of intron retention (IR) events from RNA-Seq data has remained an unresolved challenge in next-generation sequencing (NGS) studies.
['Yang Bai', 'Shufan Ji', 'Yadong Wang']
IRcall and IRclassifier: two methods for flexible detection of intron retention events from RNA-Seq data