The drug-minded protein interaction database (DrumPID) has been designed to provide fast, tailored information on drugs and their protein networks including indications, pro- tein targets and side-targets. Starting queries include compound, target and protein interactions and organism-specific protein families. Furthermore, drug name, chemical structures and their SMILES notation, affected proteins (potential drug targets), organ- isms as well as diseases can be queried including various combinations and refinement of searches. Drugs and protein interactions are analyzed in detail with reference to pro- tein structures and catalytic domains, related compound structures as well as potential targets in other organisms. DrumPID considers drug functionality, compound similarity, target structure, interactome analysis and organismic range for a compound, useful for drug development, predicting drug side-effects and structure-activity relationships. Database URL: http://drumpid.bioapps.biozentrum.uni-wuerzburg.de
['Meik Kunz', 'Chunguang Liang', 'Santosh Nilla', 'Alexander Cecil', 'Thomas Dandekar']
The drug-minded protein interaction database (DrumPID) for efficient target analysis and drug development