Background#R##N#Detection of tandem duplication within coding exons, referred to as internal tandem duplication (ITD), remains challenging due to inefficiencies in alignment of ITD-containing reads to the reference genome. There is a critical need to develop efficient methods to recover these important mutational events.
['Navin Rustagi', 'Oliver A. Hampton', 'Jie Li', 'Liu Xi', 'Richard A. Gibbs', 'Sharon E. Plon', 'Marek Kimmel', 'David A. Wheeler']
ITD assembler: an algorithm for internal tandem duplication discovery from short-read sequencing data