Background#R##N#Differential gene expression patterns in cells of the mammalian brain result in the morphological, connectional, and functional diversity of cells. A wide variety of studies have shown that certain genes are expressed only in specific cell-types. Analysis of cell-type-specific gene expression patterns can provide insights into the relationship between genes, connectivity, brain regions, and cell-types. However, automated methods for identifying cell-type-specific genes are lacking to date.
['Rongjian Li', 'Wenlu Zhang', 'Shuiwang Ji']
Automated identification of cell-type-specific genes in the mouse brain by image computing of expression patterns.