We present a general behavioral simulation method for the approximate solution of lumped, pressure-driven, static and time-dependent solute and solvent transport in large microfluidic chips. The method is based on a one-dimensional discretization of the convection-diffusion equation that tracks solvent and solute transport using four dual-branch nodal quantities. A comparison of static and transient behavior of microfluidic dilution networks and a PCM signal generator indicates that the simulation results are in good agreement with the model simulations.
['Yi Zeng', 'Farouk Azizi', 'Carlos H. Mastrangelo']
Behavioral modeling of solute tracking in microfluidics