The immune epitope database analysis resource (IEDB-AR: http://tools.iedb.org) is a collection of tools for prediction and analysis of molecular targets of T- and B-cell immune responses (i.e. epitopes). Since its last publication in the NAR webserver issue in 2008, a new generation of peptide:MHC binding and T-cell epitope predictive tools have been added. As validated by different labs and in the first international competition for predicting peptide:MHC-I binding, their predictive performances have improved considerably. In addition, a new B-cell epitope prediction tool was added, and the homology mapping tool was updated to enable mapping of discontinuous epitopes onto 3D structures. Furthermore, to serve a wider range of users, the number of ways in which IEDB-AR can be accessed has been expanded. Specifically, the predictive tools can be programmatically accessed using a web interface and can also be downloaded as software packages.
['Yohan Kim', 'Julia V. Ponomarenko', 'Zhanyang Zhu', 'Dorjee G. Tamang', 'Peng Wang', 'Jason Greenbaum', 'Claus Lundegaard', 'Alessandro Sette', 'Ole Lund', 'Philip E. Bourne', 'Morten A. Nielsen', 'Bjoern Peters']
Immune epitope database analysis resource