Summary: Multiple templates can often be used to build more accurate homology models than models built from a single template. Here we introduce PconsM, an automated protocol that uses multiple templates to build protein models. PconsM has been among the top-performing methods in the recent CASP experiments and consistently perform better than the single template models used in Pcons.net. In particular for the easier targets with many alternative templates with a high degree of sequence identity, quality is readily improved with a few percentages over the highest ranked model built on a single template. PconsM is available as an additional pipeline within the Pcons.net protein structure prediction server.#R##N##R##N#Availability and implementation: PconsM is freely available from http://pcons.net/.#R##N##R##N#Contact: arne@bioinfo.se
['Per Larsson', 'Marcin J. Skwark', 'Björn Wallner', 'Arne Elofsson']
Improved predictions by Pcons.net using multiple templates