Evaluation of biological activity of multi cellular spheroids with label-free technique is quite important. Therefore, we focused on mechanical characterization of spheroids using force sensor probe using quartz crystal resonator (QCR). In this study, we measured the mechanical characteristics of HepG2 spheroid with different culture periods.
['Ayaka Sato', 'Shinya Sakuma', 'Nobuhiko Kojima', 'Fumiya Tao', 'Fumihito Arai']
Mechanical characterization of spheroids by force sensor probe using quartz crystal resonator