Background#R##N#The identification of promoter regions that are regulated by a given transcription factor has traditionally relied upon the identification and distributions of binding sites recognized by the factor. In this study, we have developed a tandem machine learning approach for the identification of regulatory target genes based on these parameters and on the corresponding binding site information contents that measure the affinities of the factor for these cognate elements.
['Deendayal Dinakarpandian', 'Venetia Raheja', 'Saumil Mehta', 'Erin G. Schuetz', 'Peter K. Rogan']
Tandem machine learning for the identification of genes regulated by transcription factors