Background#R##N#Imputation is a statistical process used to predict genotypes of loci not directly assayed in a sample of individuals. Our goal is to measure the performance of imputation in predicting the genotype of the best known gene polymorphisms involved in drug metabolism using a common SNP array genotyping platform generally exploited in genome wide association studies.
['Vladan Mijatovic', 'Ilaria Iacobucci', 'Marco Sazzini', 'L. Xumerle', 'Antonio Mori', 'Pier Franco Pignatti', 'Giovanni Martinelli', 'Giovanni Malerba']
Imputation reliability on DNA biallelic markers for drug metabolism studies