Background#R##N#Methods for inferring signaling networks using single gene knockdown RNAi experiments and reference networks have been proposed in recent years. These methods assume that RNAi information is available for all the genes in the signal transduction pathway, i.e., complete. This assumption does not always hold up since RNAi experiments are often incomplete and information for some genes is missing.
['Yuanfang Ren', 'Qiyao Wang', 'Mahmudul Hasan', 'Ahmet Ay', 'Tamer Kahveci']
Identifying the topology of signaling networks from partial RNAi data