Background#R##N#Alternative sequence alignment algorithms yield different results. It is therefore useful to quantify the similarities and differences between alternative alignments of the same sequences. These measurements can identify regions of consensus that are likely to be most informative in downstream analysis. They can also highlight systematic differences between alignments that relate to differences in the alignment algorithms themselves.
['Thomas M. A. Shafee', 'Ira R. Cooke']
AlignStat: a web-tool and R package for statistical comparison of alternative multiple sequence alignments