Background#R##N#Clostridium acetobutylicum is an anaerobic bacterium which is known for its solvent-producing capabilities, namely regarding the bulk chemicals acetone and butanol, the latter being a highly efficient biofuel. For butanol production by C. acetobutylicum to be optimized and exploited on an industrial scale, the effect of pH-induced gene regulation on solvent production by C. acetobutylicum in continuous culture must be understood as fully as possible.
['Sylvia Haus', 'Sara Jabbari', 'Thomas Millat', 'Holger Janssen', 'Ralf-Jörg Fischer', 'Hubert Bahl', 'John R. King', 'Olaf Wolkenhauer']
A systems biology approach to investigate the effect of pH-induced gene regulation on solvent production by Clostridium acetobutylicum in continuous culture.