Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Wall Shear Stress is a key factor in the development of atherosclerosis. To assess the WSS in-vivo, velocity encoded MRI is combined with geometry measurements by 3D MR-Angiography (MRA) and with blood flow calculations using the Finite Element Method (FEM). The 3D geometry extracted from the MRA data was converted to a mesh suitable for FEM calculations. Aiming at in-vivo studies the goal of this study was to quantify the differences beten FEM calculations and MRI measurements. Two phantoms, a curved tube and a carotid bifurcation model re used. The geometry and the time-dependent flow-rate (measured by MRI) formed input for the FEM calculations. For good data quality, 2D velocity profiles re analyzed further by the Kolmogorov-Smirnov method. For the curved tube calculations and measurements matched ll (prob?S approximately above 0.20). The carotid needs further investigation in segmentation and simulation to obtain similar results. It can be concluded that the error-analysis performs reliably.
['Frieke M.A. Box', 'Marcel Rutten', 'Mark A. van Buchem', 'Joost Doornbos', 'Rob J. van der Geest', 'Patrick J.H. de Koning', 'J.A. Schaap', 'Frans N. van de Vosse', 'Johan H. C. Reiber']
I am writing a research paper on a idea Quantitative Methods for Comparisons between Velocity Encoded MR-Measurements and Finite Element Modeling in Phantom Models
[{"from": "human", "value": "I am writing a research paper on a idea Quantitative Methods for Comparisons between Velocity Encoded MR-Measurements and Finite Element Modeling in Phantom Models"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Wall Shear Stress is a key factor in the development of atherosclerosis. To assess the WSS in-vivo, velocity encoded MRI is combined with geometry measurements by 3D MR-Angiography (MRA) and with blood flow calculations using the Finite Element Method (FEM). The 3D geometry extracted from the MRA data was converted to a mesh suitable for FEM calculations. Aiming at in-vivo studies the goal of this study was to quantify the differences beten FEM calculations and MRI measurements. Two phantoms, a curved tube and a carotid bifurcation model re used. The geometry and the time-dependent flow-rate (measured by MRI) formed input for the FEM calculations. For good data quality, 2D velocity profiles re analyzed further by the Kolmogorov-Smirnov method. For the curved tube calculations and measurements matched ll (prob?S approximately above 0.20). The carotid needs further investigation in segmentation and simulation to obtain similar results. It can be concluded that the error-analysis performs reliably."}]