Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Reconstruct and quantify the RNA molecules in a cell at a given moment is an important problem in molecular biology that allows one to know which genes are being expressed and at which intensity level. Such problem is known as transcriptome reconstruction and quantification problem TRQP. Although several approaches re already designed for the TRQP, none of them model it as a combinatorial optimisation problem over strings. In order to narrow this gap,  present here a new combinatorial optimisation problem called maximum similarity partitioning problem MSPP that models the TRQP. In addition,  prove that the MSPP is NP-complete in the strong sense and present a greedy heuristic for it and some experimental results.
['Alex Z. Zaccaron', 'Said Sadique Adi', 'Carlos H. A. Higa', 'Eloi Araujo']
I am writing a research paper on a idea The maximum similarity partitioning problem and its application in the transcriptome reconstruction and quantification problem
[{"from": "human", "value": "I am writing a research paper on a idea The maximum similarity partitioning problem and its application in the transcriptome reconstruction and quantification problem"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Reconstruct and quantify the RNA molecules in a cell at a given moment is an important problem in molecular biology that allows one to know which genes are being expressed and at which intensity level. Such problem is known as transcriptome reconstruction and quantification problem TRQP. Although several approaches re already designed for the TRQP, none of them model it as a combinatorial optimisation problem over strings. In order to narrow this gap,  present here a new combinatorial optimisation problem called maximum similarity partitioning problem MSPP that models the TRQP. In addition,  prove that the MSPP is NP-complete in the strong sense and present a greedy heuristic for it and some experimental results."}]