Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: This work demonstrates a microfluidic platform to study and differentiate avian red blood cells infected to various degrees by the malaria parasite Plasmodium gallinaceum. The preliminary finding points to the feasibility of using the morphological changes on the surface of the malaria infected avian RBC (miaRBC) as biomarkers for diagnosis. By embedding a glass substrate with a controlled surface roughness in a polydimethylsiloxane (PDMS) microfluidic channels, the surface lesions and furrow-like structures on the miaRBC surfaces could interact with the substrate and be separated at 3.2%, 3.9%, 9.1%, 13.4%, and 20.1% infections. It was estimated that the miaRBCs could be selectively captured under a wall shear rate beten 2.1 to 3.2 s −1 , and could be improved by increasing the channel length and finer flow control.
['Yu-Hsiang Hsu', 'Peiran Lu', 'William C. Tang']
I am writing a research paper on a idea Microplatforms for avian malaria studies
[{"from": "human", "value": "I am writing a research paper on a idea Microplatforms for avian malaria studies"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: This work demonstrates a microfluidic platform to study and differentiate avian red blood cells infected to various degrees by the malaria parasite Plasmodium gallinaceum. The preliminary finding points to the feasibility of using the morphological changes on the surface of the malaria infected avian RBC (miaRBC) as biomarkers for diagnosis. By embedding a glass substrate with a controlled surface roughness in a polydimethylsiloxane (PDMS) microfluidic channels, the surface lesions and furrow-like structures on the miaRBC surfaces could interact with the substrate and be separated at 3.2%, 3.9%, 9.1%, 13.4%, and 20.1% infections. It was estimated that the miaRBCs could be selectively captured under a wall shear rate beten 2.1 to 3.2 s \u22121 , and could be improved by increasing the channel length and finer flow control."}]