Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Summary: A standard systems-based approach to biomarker and drug target discovery consists of placing putative biomarkers in the context of a network of biological interactions, follod by different ‘guilt-by-association’ analyses. The latter is typically done based on network structural features. Here, an alternative analysis approach in which the networks are analyzed on a ‘semantic similarity’ space is reported. Such information is extracted from ontology-based functional annotations.  present SimTrek, a Cytoscape plugin for ontology-based similarity assessment in biological networks.#R##N##R##N#Availability: http://rosalind.infj.ulst.ac.uk/SimTrek.html #R##N##R##N#Contact: francisco.azuaje@crp-sante.lu#R##N##R##N#Supplementary information:Supplementary data are available at Bioinformatics online.
['Haiying Wang', 'Huiru Zheng', 'Francisco Azuaje']
I am writing a research paper on a idea Ontology-and graph-based similarity assessment in biological networks
[{"from": "human", "value": "I am writing a research paper on a idea Ontology-and graph-based similarity assessment in biological networks"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Summary: A standard systems-based approach to biomarker and drug target discovery consists of placing putative biomarkers in the context of a network of biological interactions, follod by different \u2018guilt-by-association\u2019 analyses. The latter is typically done based on network structural features. Here, an alternative analysis approach in which the networks are analyzed on a \u2018semantic similarity\u2019 space is reported. Such information is extracted from ontology-based functional annotations.  present SimTrek, a Cytoscape plugin for ontology-based similarity assessment in biological networks.#R##N##R##N#Availability: http://rosalind.infj.ulst.ac.uk/SimTrek.html #R##N##R##N#Contact: francisco.azuaje@crp-sante.lu#R##N##R##N#Supplementary information:Supplementary data are available at Bioinformatics online."}]