Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely:  introduces a novel molecular descriptiontopological (2D) fuzzy pharmacophore triplets, 2D-FPTusing the number of interposed bonds as the measure of separation beten the atoms representing pharmacophore types (hydrophobic, aromatic, hydrogen-bond donor and acceptor, cation, and anion). 2D-FPT features three key improvements with respect to the state-of-the-art pharmacophore fingerprints:  (1) The first key novelty is fuzzy mapping of molecular triplets onto the basis set of pharmacophore triplets: unlike in the binary scheme where an atom triplet is set to highlight the bit of a single, best-matching basis triplet, the herein-defined fuzzy approach allows for gradual mapping of each atom triplet onto several related basis triplets, thus minimizing binary classification artifacts. (2) The second innovation is proteolytic equilibrium dependence, by explicitly considering all of the conjugated acids and bases (microspecies). 2D-FPTs are concentration-ighted (as predicted at pH = 7.4) averages o...
['Fanny Bonachera', 'Benjamin Parent', 'Frédérique Barbosa', 'Nicolas Froloff', 'Dragos Horvath']
I am writing a research paper on a idea Fuzzy tricentric pharmacophore fingerprints. I am writing a research paper on a idea 1. I am writing a research paper on a idea Topological fuzzy pharmacophore triplets and adapted molecular similarity scoring schemes.
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