Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: ,  present a study on the relationships beten Chronic Lymphocytic Leukemia (CLL) related clinical attributes using network visualization and analysis techniques. This work is the first step of our long-term project to identify novel biomarkers for CLL, working in coordination with the NCI-funded CLL Research Consortium (cll.ucsd.edu).By computing Spearman correlation coefficients for 125 clinical attributes,  established an attribute network for CLL. Using network visualization techniques  identified a core network with peripheral nodes around it. An important observation is that many cytogenetic attributes are in the core network, indicating the connection beten karyotypes (e.g., abnormality in Chromosome 17) and other clinical attributes. Since these karyotypes are linked to CLL etiology in many ways, the corresponding clinical attributes may be further selected and tested as markers for disease screening.The correlation analysis results are also consistent with previous studies using a knowledge engineering based approach for establishing relationships beten such attributes.
['Abhisek Kundu', 'Hatice Gulcin Ozer', 'Tara Borlawsky', 'Kristin Circle', 'Kun Huang', 'Philip R. O. Payne']
I am writing a research paper on a idea Clinical Attribute Network for Chronic Lymphocytic Leukemia
[{"from": "human", "value": "I am writing a research paper on a idea Clinical Attribute Network for Chronic Lymphocytic Leukemia"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: ,  present a study on the relationships beten Chronic Lymphocytic Leukemia (CLL) related clinical attributes using network visualization and analysis techniques. This work is the first step of our long-term project to identify novel biomarkers for CLL, working in coordination with the NCI-funded CLL Research Consortium (cll.ucsd.edu).By computing Spearman correlation coefficients for 125 clinical attributes,  established an attribute network for CLL. Using network visualization techniques  identified a core network with peripheral nodes around it. An important observation is that many cytogenetic attributes are in the core network, indicating the connection beten karyotypes (e.g., abnormality in Chromosome 17) and other clinical attributes. Since these karyotypes are linked to CLL etiology in many ways, the corresponding clinical attributes may be further selected and tested as markers for disease screening.The correlation analysis results are also consistent with previous studies using a knowledge engineering based approach for establishing relationships beten such attributes."}]