Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Background#R##N#MicroRNAs (simply miRNAs) are derived from larger hairpin RNA precursors and play essential regular roles in both animals and plants. A number of computational methods for miRNA genes finding have been proposed in the past decade, yet the problem is far from being tackled, especially when considering the imbalance issue of known miRNAs and unidentified miRNAs, and the pre-miRNAs with multi-loops or higher minimum free energy (MFE).  presents a new computational approach, miRenSVM, for finding miRNA genes. Aiming at better prediction performance, an ensemble support vector machine (SVM) classifier is established to deal with the imbalance issue, and multi-loop features are included for identifying those pre-miRNAs with multi-loops.
['Jiandong Ding', 'Shuigeng Zhou', 'Jihong Guan']
I am writing a research paper on a idea MiRenSVM: towards better prediction of microRNA precursors using an ensemble SVM classifier with multi-loop features
[{"from": "human", "value": "I am writing a research paper on a idea MiRenSVM: towards better prediction of microRNA precursors using an ensemble SVM classifier with multi-loop features"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Background#R##N#MicroRNAs (simply miRNAs) are derived from larger hairpin RNA precursors and play essential regular roles in both animals and plants. A number of computational methods for miRNA genes finding have been proposed in the past decade, yet the problem is far from being tackled, especially when considering the imbalance issue of known miRNAs and unidentified miRNAs, and the pre-miRNAs with multi-loops or higher minimum free energy (MFE).  presents a new computational approach, miRenSVM, for finding miRNA genes. Aiming at better prediction performance, an ensemble support vector machine (SVM) classifier is established to deal with the imbalance issue, and multi-loop features are included for identifying those pre-miRNAs with multi-loops."}]