Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Motivation: Currently, there are no ontologies capable of describing both the spatial organization of groups of cells and the behaviors of those cells. The lack of a formalized method for describing the spatiality and intrinsic biological behaviors of cells makes it difficult to adequately describe cells, tissues and organs as spatial objects in living tissues, in vitro assays and in computational models of tissues.#R##N##R##N#Results:  have developed an OWL-2 ontology to describe the intrinsic physical and biological characteristics of cells and tissues. The Cell Behavior Ontology (CBO) provides a basis for describing the spatial and observable behaviors of cells and extracellular components suitable for describing in vivo, in vitro and in silico multicell systems. Using the CBO, a modeler can create a meta-model of a simulation of a biological model and link that meta-model to experiment or simulation results. Annotation of a multicell model and its computational representation, using the CBO, makes the statement of the underlying biology explicit. The formal representation of such biological abstraction facilitates the validation, falsification, discovery, sharing and reuse of both models and experimental data.#R##N##R##N#Availability and implementation: The CBO, developed using Protege 4, is available at http://cbo.biocomplexity.indiana.edu/cbo/ and at BioPortal (http://bioportal.bioontology.org/ontologies/CBO).#R##N##R##N#Contact: ude.anaidni@akulsj or ude.anaidni@reizalG#R##N##R##N#Supplementary information: Supplementary data are available at Bioinformatics online.
['James P. Sluka', 'Abbas Shirinifard', 'Maciej Swat', 'Alin Cosmanescu', 'Randy Heiland', 'James A. Glazier']
I am writing a research paper on a idea The cell behavior ontology: describing the intrinsic biological behaviors of real and model cells seen as active agents
[{"from": "human", "value": "I am writing a research paper on a idea The cell behavior ontology: describing the intrinsic biological behaviors of real and model cells seen as active agents"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Motivation: Currently, there are no ontologies capable of describing both the spatial organization of groups of cells and the behaviors of those cells. The lack of a formalized method for describing the spatiality and intrinsic biological behaviors of cells makes it difficult to adequately describe cells, tissues and organs as spatial objects in living tissues, in vitro assays and in computational models of tissues.#R##N##R##N#Results:  have developed an OWL-2 ontology to describe the intrinsic physical and biological characteristics of cells and tissues. The Cell Behavior Ontology (CBO) provides a basis for describing the spatial and observable behaviors of cells and extracellular components suitable for describing in vivo, in vitro and in silico multicell systems. Using the CBO, a modeler can create a meta-model of a simulation of a biological model and link that meta-model to experiment or simulation results. Annotation of a multicell model and its computational representation, using the CBO, makes the statement of the underlying biology explicit. The formal representation of such biological abstraction facilitates the validation, falsification, discovery, sharing and reuse of both models and experimental data.#R##N##R##N#Availability and implementation: The CBO, developed using Protege 4, is available at http://cbo.biocomplexity.indiana.edu/cbo/ and at BioPortal (http://bioportal.bioontology.org/ontologies/CBO).#R##N##R##N#Contact: ude.anaidni@akulsj or ude.anaidni@reizalG#R##N##R##N#Supplementary information: Supplementary data are available at Bioinformatics online."}]