Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: The investigation of bone fragility diseases, as osteoporosis, is based on the analysis of the trabecular bone microarchitecture. The aim of this paper is to improve the in-vivo trabecular bone segmentation and quantification by increasing the resolution of bone micro-architecture images.  propose a semi-blind joint super-resolution/segmentation approach based on a Total Variation regularization with a convex constraint. A comparison with the bicubic interpolation method and the non-blind version of the proposed method is shown. The validation is performed on blurred, noisy and down-sampled 3D synchrotron micro-CT bone images. Good estimates of the blur and of the high resolution image are obtained with the semi-blind approach. Preliminary results are obtained with the semi-blind approach on real HR-pQCT images.
['Françoise Peyrin', 'Alina Toma', 'Bruno Sixou', 'Loïc Denis', 'Andrew J. Burghardt', 'Jean-Baptiste Pialat']
I am writing a research paper on a idea Semi-blind joint super-resolution/segmentation of 3D trabecular bone images by a TV box approach
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