Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: The naive use of expression ratios in high-throughput biological studies can greatly limit analytical outcome especially when sample size is small. In the worst-case scenario, with only one reference and one test state each often due to the severe lack of study material; such limitations make it difficult to perform statistically meaningful analysis. Workarounds include the single sample Z-test or through network inference. Here,  describe a complementary plot-based approach for analysing such extremely small sized ratio ESSR data - a generalisation of the Bland-Altman plot, which  shall refer to as the Dodeca-Panels. Included in this paper is an R implementation of the Dodeca-Panels method.
['Piero Ricchiuto', 'Judy Chia Ghee Sng', 'Wilson Wen Bin Goh']
I am writing a research paper on a idea Analysing extremely small sized ratio datasets
[{"from": "human", "value": "I am writing a research paper on a idea Analysing extremely small sized ratio datasets"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: The naive use of expression ratios in high-throughput biological studies can greatly limit analytical outcome especially when sample size is small. In the worst-case scenario, with only one reference and one test state each often due to the severe lack of study material; such limitations make it difficult to perform statistically meaningful analysis. Workarounds include the single sample Z-test or through network inference. Here,  describe a complementary plot-based approach for analysing such extremely small sized ratio ESSR data - a generalisation of the Bland-Altman plot, which  shall refer to as the Dodeca-Panels. Included in this paper is an R implementation of the Dodeca-Panels method."}]