Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: FLAN (short for FLu ANnotation), the NCBI b server for genome annotation of influenza virus (http://www.ncbi.nlm.nih.gov/genomes/FLU/ Database/annotation.cgi) is a tool for user-provided influenza A virus or influenza B virus sequences. It can validate and predict protein sequences encoded by an input flu sequence. The input sequence is BLASTed against a database containing influenza sequences to determine the virus type (A or B), segment (1 through 8) and subtype for the hemagglutinin and neuraminidase segments of influenza A virus. For each segment/subtype of the viruses, a set of sample protein sequences is maintained. The input sequence is then aligned against the corresponding protein set with a ‘Protein to nucleotide alignment tool’ (ProSplign). The translated product from the best alignment to the sample protein sequence is used as the predicted protein encoded by the input sequence. The output can be a feature table that can be used for sequence submission to GenBank (by Sequin or tbl2asn), a GenBank flat file, or the predicted protein sequences in FASTA format. A message showing the length of the input sequence, the predicted virus type, segment and subtype for the hemagglutinin and neuraminidase segments of Influenza A virus will also be displayed.
['Yiming Bao', 'Pavel Bolotov', 'Dmitry Dernovoy', 'Boris Kiryutin', 'Tatiana Tatusova']
I am writing a research paper on a idea FLAN: a web server for influenza virus genome annotation.
[{"from": "human", "value": "I am writing a research paper on a idea FLAN: a web server for influenza virus genome annotation."}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: FLAN (short for FLu ANnotation), the NCBI b server for genome annotation of influenza virus (http://www.ncbi.nlm.nih.gov/genomes/FLU/ Database/annotation.cgi) is a tool for user-provided influenza A virus or influenza B virus sequences. It can validate and predict protein sequences encoded by an input flu sequence. The input sequence is BLASTed against a database containing influenza sequences to determine the virus type (A or B), segment (1 through 8) and subtype for the hemagglutinin and neuraminidase segments of influenza A virus. For each segment/subtype of the viruses, a set of sample protein sequences is maintained. The input sequence is then aligned against the corresponding protein set with a \u2018Protein to nucleotide alignment tool\u2019 (ProSplign). The translated product from the best alignment to the sample protein sequence is used as the predicted protein encoded by the input sequence. The output can be a feature table that can be used for sequence submission to GenBank (by Sequin or tbl2asn), a GenBank flat file, or the predicted protein sequences in FASTA format. A message showing the length of the input sequence, the predicted virus type, segment and subtype for the hemagglutinin and neuraminidase segments of Influenza A virus will also be displayed."}]