Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: A potentiometric electronic tongue was applied to study the release of valsartan from pharmaceutical formulations, i.e., minitablets uncoated and coated with Eudragit E. Special attention was paid to evaluate the influence of medium temperature and composition, as ll as to compare the performances of the sensor arrays working in various hydrodynamic conditions. The drug dissolution profiles registered with the ion-sensitive electrodes re compared with standard dissolution tests performed with USP Apparatus 2 (paddle). Moreover, the signal changes of all sensors re processed by principal component analysis to visualize the release modifications, related to the presence of the coating agent. Finally, the importance and influence of the experimental conditions on the results obtained using potentiometric sensor arrays re discussed.
['Małgorzata Wesoły', 'Anna Kluk', 'Malgorzata Sznitowska', 'Patrycja Ciosek', 'Wojciech Wroblewski']
I am writing a research paper on a idea Influence of Experimental Conditions on Electronic Tongue Results—Case of Valsartan Minitablets Dissolution
[{"from": "human", "value": "I am writing a research paper on a idea Influence of Experimental Conditions on Electronic Tongue Results\u2014Case of Valsartan Minitablets Dissolution"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: A potentiometric electronic tongue was applied to study the release of valsartan from pharmaceutical formulations, i.e., minitablets uncoated and coated with Eudragit E. Special attention was paid to evaluate the influence of medium temperature and composition, as ll as to compare the performances of the sensor arrays working in various hydrodynamic conditions. The drug dissolution profiles registered with the ion-sensitive electrodes re compared with standard dissolution tests performed with USP Apparatus 2 (paddle). Moreover, the signal changes of all sensors re processed by principal component analysis to visualize the release modifications, related to the presence of the coating agent. Finally, the importance and influence of the experimental conditions on the results obtained using potentiometric sensor arrays re discussed."}]