Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: The EzCatDB (Enzyme Catalytic-mechanism Database) specifically includes catalytic mechanisms of enzymes in terms of sequences and tertiary structures of enzymes, and proposed catalytic mechanisms, along with ligand structures. The EzCatDB groups enzyme data in the Protein Data Bank (PDB) and the SWISS-PROT database with identical domain compositions, Enzyme Commission (EC) numbers and catalytic mechanisms. The EzCatDB can be queried by the type of catalytic residue, name and type of ligand molecule that interacts with an enzyme as a cofactor, substrate or product. It can provide literature information, other database codes and EC numbers. The EzCatDB provides ligand annotation for enzymes in the PDB as ll as literature information on structure and catalytic mechanisms. Furthermore, the EzCatDB also provides a hierarchic classification of catalytic mechanisms. This classification incorporates catalytic mechanisms and active-site structures of enzymes as ll as basic reactions and reactive parts of ligand molecules. The EzCatDB is available at http://mbs.cbrc.jp/EzCatDB/.
['Nozomi Nagano']
I am writing a research paper on a idea EzCatDB: the Enzyme Catalytic-mechanism Database
[{"from": "human", "value": "I am writing a research paper on a idea EzCatDB: the Enzyme Catalytic-mechanism Database"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: The EzCatDB (Enzyme Catalytic-mechanism Database) specifically includes catalytic mechanisms of enzymes in terms of sequences and tertiary structures of enzymes, and proposed catalytic mechanisms, along with ligand structures. The EzCatDB groups enzyme data in the Protein Data Bank (PDB) and the SWISS-PROT database with identical domain compositions, Enzyme Commission (EC) numbers and catalytic mechanisms. The EzCatDB can be queried by the type of catalytic residue, name and type of ligand molecule that interacts with an enzyme as a cofactor, substrate or product. It can provide literature information, other database codes and EC numbers. The EzCatDB provides ligand annotation for enzymes in the PDB as ll as literature information on structure and catalytic mechanisms. Furthermore, the EzCatDB also provides a hierarchic classification of catalytic mechanisms. This classification incorporates catalytic mechanisms and active-site structures of enzymes as ll as basic reactions and reactive parts of ligand molecules. The EzCatDB is available at http://mbs.cbrc.jp/EzCatDB/."}]