Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Dead-end elimination (DEE) is a porful theorem for selecting optimal protein side-chain orientations from a large set of discrete conformations. The present work describes a new approach to dead-end elimination that effectively splits conformational space into partitions to more efficiently eliminate dead-ending rotamers. Split DEE makes it possible to complete protein design calculations that re previously intractable due to the combinatorial explosion of intermediate conformations generated during the convergence process.
['Niles A. Pierce', 'Jan A. Spriet', 'Johan Desmet', 'Stephen L. Mayo']
I am writing a research paper on a idea Conformational splitting: A more powerful criterion for dead‐end elimination
[{"from": "human", "value": "I am writing a research paper on a idea Conformational splitting: A more powerful criterion for dead\u2010end elimination"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Dead-end elimination (DEE) is a porful theorem for selecting optimal protein side-chain orientations from a large set of discrete conformations. The present work describes a new approach to dead-end elimination that effectively splits conformational space into partitions to more efficiently eliminate dead-ending rotamers. Split DEE makes it possible to complete protein design calculations that re previously intractable due to the combinatorial explosion of intermediate conformations generated during the convergence process."}]