Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: The use of potential biasing and biphasic, asymmetric current pulse waveforms to maximize the charge-injection capacity of activated iridium oxide (AIROF) microelectrodes used for neural stimulation is described. The waveforms retain overall zero net charge for the biphasic pulse, but employ an asymmetry in the current and pulse widths of each phase, with the second phase delivered at a lor current density for a longer period of time than the leading phase. This strategy minimizes polarization of the AIROF by the charge-balancing second phase and permits the use of a more positive anodic bias for cathodal-first pulsing or a more negative cathodic bias for anodal-first pulsing to maximize charge injection. Using 0.4-ms cathodal-first pulses, a maximum charge-injection capacity of 3.3 mC/cm/sup 2/ was obtained with an 0.6-V bias (versus Ag|AgCl) and a pulse asymmetry of 1:8 in the cathodal and anodal pulse widths. For anodal-first pulsing, a maximum charge capacity of 9.6 mC/cm/sup 2/ was obtained with an asymmetry of 1:3 at an 0.1-V bias. These measurements re made in vitro in carbonate-buffered saline using microelectrodes with a 2000 /spl mu/m/sup 2/ surface area.
['Stuart F. Cogan', 'Philip R. Troyk', 'Julia Ehrlich', 'Timothy D. Plante', 'D.E.A. Detlefsen']
I am writing a research paper on a idea Potential-biased, asymmetric waveforms for charge-injection with activated iridium oxide (AIROF) neural stimulation electrodes
[{"from": "human", "value": "I am writing a research paper on a idea Potential-biased, asymmetric waveforms for charge-injection with activated iridium oxide (AIROF) neural stimulation electrodes"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: The use of potential biasing and biphasic, asymmetric current pulse waveforms to maximize the charge-injection capacity of activated iridium oxide (AIROF) microelectrodes used for neural stimulation is described. The waveforms retain overall zero net charge for the biphasic pulse, but employ an asymmetry in the current and pulse widths of each phase, with the second phase delivered at a lor current density for a longer period of time than the leading phase. This strategy minimizes polarization of the AIROF by the charge-balancing second phase and permits the use of a more positive anodic bias for cathodal-first pulsing or a more negative cathodic bias for anodal-first pulsing to maximize charge injection. Using 0.4-ms cathodal-first pulses, a maximum charge-injection capacity of 3.3 mC/cm/sup 2/ was obtained with an 0.6-V bias (versus Ag|AgCl) and a pulse asymmetry of 1:8 in the cathodal and anodal pulse widths. For anodal-first pulsing, a maximum charge capacity of 9.6 mC/cm/sup 2/ was obtained with an asymmetry of 1:3 at an 0.1-V bias. These measurements re made in vitro in carbonate-buffered saline using microelectrodes with a 2000 /spl mu/m/sup 2/ surface area."}]