Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Motivation: Upgrade and integration of triplex software into the R/Bioconductor framework. Results:  combined a previously published implementation of a triplex DNA search algorithm with visualization to create a versatile R/Bioconductor package ‘triplex’. The new package provides functions that can be used to search Bioconductor genomes and other DNA sequence data for occurrence of nucleotide patterns capable of forming intramolecular triplexes (H-DNA). Functions producing 2D and 3D diagrams of the identified triplexes allow instant visualization of the search results. Leveraging the por of Biostrings and GRanges classes, the results get fully integrated into the existing Bioconductor framework, allowing their passage to other Genome visualization and annotation packages, such as GenomeGraphs, rtracklayer or Gviz. Availability: Rp ackage‘triplex’ is available from Bioconductor
['Jiří Hon', 'Tomáš Martínek', 'Kamil Rajdl', 'Matej Lexa']
I am writing a research paper on a idea Triplex: an R/Bioconductor package for identification and visualization of potential intramolecular triplex patterns in DNA sequences
[{"from": "human", "value": "I am writing a research paper on a idea Triplex: an R/Bioconductor package for identification and visualization of potential intramolecular triplex patterns in DNA sequences"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Motivation: Upgrade and integration of triplex software into the R/Bioconductor framework. Results:  combined a previously published implementation of a triplex DNA search algorithm with visualization to create a versatile R/Bioconductor package \u2018triplex\u2019. The new package provides functions that can be used to search Bioconductor genomes and other DNA sequence data for occurrence of nucleotide patterns capable of forming intramolecular triplexes (H-DNA). Functions producing 2D and 3D diagrams of the identified triplexes allow instant visualization of the search results. Leveraging the por of Biostrings and GRanges classes, the results get fully integrated into the existing Bioconductor framework, allowing their passage to other Genome visualization and annotation packages, such as GenomeGraphs, rtracklayer or Gviz. Availability: Rp ackage\u2018triplex\u2019 is available from Bioconductor"}]