Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: The aim of this paper was to analyze the P-wave variability over time in patients suffering from Atrial Fibrillation (AF). Behind some time-domain and morphological features of the P-wave template, two novel indexes of P-wave variability have been estimated: one based on the cross-correlation coefficients among the P-waves (Correlation Index, CI), and one associated to variation of P-waves amplitude (Amplitude Index, AI). These indexes re estimated in two experimental models: patients suffering from persistent AF respect to control subjects and patients developing post-operative AF (POAF) after coronary artery bypass grafting respect to patients without POAF. The control group resulted to be characterized by shorter P-wave duration and by a less amount of fragmentation and variability, respect to AF patients (with a sensitivity and specificity of 98.4% and 95 % respectively). Also P-wave features resulted to be different for patients with POAF respect to patients without. In conclusion the quantification of the P-wave variability over time can add information in the understanding of the association beten the anatomical atrial substrate and atrial arrhythmias.
['Federica Censi', 'Giovanni Calcagnini', 'Eugenio Mattei', 'Alessandro Ricci', 'Ivan Corazza', 'Elisa Reggiani', 'Giuseppe Boriani']
I am writing a research paper on a idea Beat-to-beat variability of P-wave in patients suffering from atrial fibrillation
[{"from": "human", "value": "I am writing a research paper on a idea Beat-to-beat variability of P-wave in patients suffering from atrial fibrillation"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: The aim of this paper was to analyze the P-wave variability over time in patients suffering from Atrial Fibrillation (AF). Behind some time-domain and morphological features of the P-wave template, two novel indexes of P-wave variability have been estimated: one based on the cross-correlation coefficients among the P-waves (Correlation Index, CI), and one associated to variation of P-waves amplitude (Amplitude Index, AI). These indexes re estimated in two experimental models: patients suffering from persistent AF respect to control subjects and patients developing post-operative AF (POAF) after coronary artery bypass grafting respect to patients without POAF. The control group resulted to be characterized by shorter P-wave duration and by a less amount of fragmentation and variability, respect to AF patients (with a sensitivity and specificity of 98.4% and 95 % respectively). Also P-wave features resulted to be different for patients with POAF respect to patients without. In conclusion the quantification of the P-wave variability over time can add information in the understanding of the association beten the anatomical atrial substrate and atrial arrhythmias."}]