Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: The central aortic blood pressure (cBP) waveform, which is different to that of peripheral locations, is a clinically important parameter for assessing cardiovascular function, hover the gold standard for measuring cBP involves invasive catheter-based techniques. The difficulties associated with invasive measurements have given rise to the development of a variety of noninvasive methods. An increasingly applied method for the noninvasive derivation of cBP involves the application of transfer function (TF) techniques to a non-invasively measured radial blood pressure (BP) waveform. The purpose of the current study was to investigate the development of a general parametric model for determination of cBP from tonometrically transduced radial BP waveforms. The study utilized simultaneously measured invasive central aortic and noninvasive radial BP waveform measurements. Data sets re available from 92 subjects, a large cohort for a study of this nature. The output error (OE) model was empirically identified as the most appropriate model structure. A generalized model was developed using a pre-specified derivation cohort and then applied to a validation data set to estimate the recognized features of the cBP waveform. While our results shod that many relevant BP parameters could be derived within acceptable limits, the estimated augmentation index (AI) displayed only a ak correlation compared to the invasively measured value, indicating that any clinical diagnosis or interpretation based on estimated AI should be undertaken with caution.
['Cagla Akalanli', 'David B. H. Tay', 'James D. Cameron']
I am writing a research paper on a idea Optimization of a generalized radial-aortic transfer function using parametric techniques.
[{"from": "human", "value": "I am writing a research paper on a idea Optimization of a generalized radial-aortic transfer function using parametric techniques."}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: The central aortic blood pressure (cBP) waveform, which is different to that of peripheral locations, is a clinically important parameter for assessing cardiovascular function, hover the gold standard for measuring cBP involves invasive catheter-based techniques. The difficulties associated with invasive measurements have given rise to the development of a variety of noninvasive methods. An increasingly applied method for the noninvasive derivation of cBP involves the application of transfer function (TF) techniques to a non-invasively measured radial blood pressure (BP) waveform. The purpose of the current study was to investigate the development of a general parametric model for determination of cBP from tonometrically transduced radial BP waveforms. The study utilized simultaneously measured invasive central aortic and noninvasive radial BP waveform measurements. Data sets re available from 92 subjects, a large cohort for a study of this nature. The output error (OE) model was empirically identified as the most appropriate model structure. A generalized model was developed using a pre-specified derivation cohort and then applied to a validation data set to estimate the recognized features of the cBP waveform. While our results shod that many relevant BP parameters could be derived within acceptable limits, the estimated augmentation index (AI) displayed only a ak correlation compared to the invasively measured value, indicating that any clinical diagnosis or interpretation based on estimated AI should be undertaken with caution."}]