Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Protein structure homology modelling has become a routine technique to generate 3D models for proteins when experimental structures are not available. Fully automated servers such as SWISS-MODEL with user-friendly b interfaces generate reliable models without the need for complex software packages or downloading large databases. Here,  describe the latest version of the SWISS-MODEL expert system for protein structure modelling. The SWISS-MODEL template library provides annotation of quaternary structure and essential ligands and co-factors to allow for building of complete structural models, including their oligomeric structure. The improved SWISS-MODEL pipeline makes extensive use of model quality estimation for selection of the most suitable templates and provides estimates of the expected accuracy of the resulting models. The accuracy of the models generated by SWISS-MODEL is continuously evaluated by the CAMEO system. The new b site allows users to interactively search for templates, cluster them by sequence similarity, structurally compare alternative templates and select the ones to be used for model building. In cases where multiple alternative template structures are available for a protein of interest, a user-guided template selection step allows building models in different functional states. SWISS-MODEL is available at http://swissmodel.expasy.org/.
['Marco Biasini', 'Stefan Bienert', 'Andrew Waterhouse', 'Konstantin Arnold', 'Gabriel Studer', 'Tobias Schmidt', 'Florian Kiefer', 'Tiziano Gallo Cassarino', 'Martino Bertoni', 'Lorenza Bordoli', 'Torsten Schwede']
I am writing a research paper on a idea SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information
[{"from": "human", "value": "I am writing a research paper on a idea SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Protein structure homology modelling has become a routine technique to generate 3D models for proteins when experimental structures are not available. Fully automated servers such as SWISS-MODEL with user-friendly b interfaces generate reliable models without the need for complex software packages or downloading large databases. Here,  describe the latest version of the SWISS-MODEL expert system for protein structure modelling. The SWISS-MODEL template library provides annotation of quaternary structure and essential ligands and co-factors to allow for building of complete structural models, including their oligomeric structure. The improved SWISS-MODEL pipeline makes extensive use of model quality estimation for selection of the most suitable templates and provides estimates of the expected accuracy of the resulting models. The accuracy of the models generated by SWISS-MODEL is continuously evaluated by the CAMEO system. The new b site allows users to interactively search for templates, cluster them by sequence similarity, structurally compare alternative templates and select the ones to be used for model building. In cases where multiple alternative template structures are available for a protein of interest, a user-guided template selection step allows building models in different functional states. SWISS-MODEL is available at http://swissmodel.expasy.org/."}]