Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: The use of near infra red (NIR) photoacoustic spectroscopy (PAS) for continuous non-invasive glucose measurement is outlined in the paper. A photoacoustic (PA) measurement apparatus was constructed and PA measurements re made on glucose solutions at multiple NIR excitation wavelengths. A variety of time and frequency domain features, including amplitude and area based features, re extracted from the PA measurements. These features re observed to be proportional to the glucose concentration of the sample. PA measurements from samples of whole blood at different glucose concentrations shod similar results. Subsequently, in vivo PA measurements made on a cohort of 30 volunteers re calibrated using a quadratic fit, and the results re compared to reference glucose concentrations made using a regular blood glucose meter. A comparison of 196 measurement pairs of predicted and reference glucose concentrations using a Clarke Error Grid gave a point distribution of 87.24% and 12.76% over zones A and B of the grid, with no measurement pairs falling in unacceptable zones C-E of the error grid. The predicted measurements had a mean absolute difference (MAD) of 12.57 ± 13.90 mg/dl and a mean absolute relative difference (MARD) of 9.61% ± 10.55%. This is an improvement over previous results obtained using PAS and other non-invasive techniques, validating the potential of PAS for continuous noninvasive glucose monitoring.
['Praful P. Pai', 'Pradyut Kumar Sanki', 'A. B. De', 'Swapna Banerjee']
I am writing a research paper on a idea NIR photoacoustic spectroscopy for non-invasive glucose measurement
[{"from": "human", "value": "I am writing a research paper on a idea NIR photoacoustic spectroscopy for non-invasive glucose measurement"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: The use of near infra red (NIR) photoacoustic spectroscopy (PAS) for continuous non-invasive glucose measurement is outlined in the paper. A photoacoustic (PA) measurement apparatus was constructed and PA measurements re made on glucose solutions at multiple NIR excitation wavelengths. A variety of time and frequency domain features, including amplitude and area based features, re extracted from the PA measurements. These features re observed to be proportional to the glucose concentration of the sample. PA measurements from samples of whole blood at different glucose concentrations shod similar results. Subsequently, in vivo PA measurements made on a cohort of 30 volunteers re calibrated using a quadratic fit, and the results re compared to reference glucose concentrations made using a regular blood glucose meter. A comparison of 196 measurement pairs of predicted and reference glucose concentrations using a Clarke Error Grid gave a point distribution of 87.24% and 12.76% over zones A and B of the grid, with no measurement pairs falling in unacceptable zones C-E of the error grid. The predicted measurements had a mean absolute difference (MAD) of 12.57 \u00b1 13.90 mg/dl and a mean absolute relative difference (MARD) of 9.61% \u00b1 10.55%. This is an improvement over previous results obtained using PAS and other non-invasive techniques, validating the potential of PAS for continuous noninvasive glucose monitoring."}]