Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: A fuzzy system with dynamically adapt the inertia ight of the particle swarm optimization (FAPSO) had been implemented to select a specific feasible primer pair for PCR experiments. Overall, fifty accession nucleotide sequences beten 1900 bps and 2100 bps re sampled for primer design with specific PCR product lengths of 150~300 bps and 500~800 bps. Total five hundred runs of the proposed primer design approaches re performed for each accession nucleotide sequence to calculate the optimum accuracy. The proposed approach is compared to standard PSO primer design method. The results generated in a dry dock experiment shod that the FAPSO primer design yielded approximately optimal primer sets and had a relatively short CPU-time than standard PSO. Related materials are available online at http://bio.kuas.edu.tw/fapso-pd/.
['Cheng-Hong Yang', 'Yu-Huei Cheng', 'Hsueh-Wei Chang', 'Li-Yeh Chuang']
I am writing a research paper on a idea Fuzzy adaptive particle swarm optimization for a specific primer design problem
[{"from": "human", "value": "I am writing a research paper on a idea Fuzzy adaptive particle swarm optimization for a specific primer design problem"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: A fuzzy system with dynamically adapt the inertia ight of the particle swarm optimization (FAPSO) had been implemented to select a specific feasible primer pair for PCR experiments. Overall, fifty accession nucleotide sequences beten 1900 bps and 2100 bps re sampled for primer design with specific PCR product lengths of 150~300 bps and 500~800 bps. Total five hundred runs of the proposed primer design approaches re performed for each accession nucleotide sequence to calculate the optimum accuracy. The proposed approach is compared to standard PSO primer design method. The results generated in a dry dock experiment shod that the FAPSO primer design yielded approximately optimal primer sets and had a relatively short CPU-time than standard PSO. Related materials are available online at http://bio.kuas.edu.tw/fapso-pd/."}]