Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Motivation: The computational prediction of protein--protein interactions is currently a major issue in bioinformatics. Recently, a variety of co-evolution-based methods have been investigated toward this goal. In this study,  introduced a partial correlation coefficient as a new measure for the degree of co-evolution beten proteins, and proposed its use to predict protein--protein interactions.#R##N##R##N#Results: The accuracy of the prediction by the proposed method was compared with those of the original mirror tree method and the projection method previously developed by our group.  found that the partial correlation coefficient effectively reduces the number of false positives, as compared with other methods, although the number of false negatives increased in the prediction by the partial correlation coefficient.#R##N##R##N#Availability: The R script for the prediction of protein--protein interactions reported in this manuscript is available at http://timpani.genome.ad.jp/~parco/#R##N##R##N#Contact: sato@kuicr.kyoto-u.ac.jp#R##N##R##N#Supplementary information: The information is also available at the same site as the R script.
['Tetsuya Sato', 'Yoshihiro Yamanishi', 'Katsuhisa Horimoto', 'Minoru Kanehisa', 'Hiroyuki Toh']
I am writing a research paper on a idea Partial correlation coefficient between distance matrices as a new indicator of protein--protein interactions
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