Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Epigenetic variation represents a mechanism of regulation for genes expressed in different cancer histotypes.  considered breast cancer, and in- vestigated differential expression following treatment with the 5-Aza-2'- deoxycytidine or DAC, a demethylating agent. Several oncogenic signalling pathways altered upon DAC treatment re detected with significant enrich- ment, and a regulatory map integrating Transcription Factors and microRNAs was derived. The ultimate goal is deciphering the potential molecular mechan- isms induced by DAC therapy in MCF7 cells.
['Mariama El Baroudi', 'Dario La Sala', 'Caterina Cinti', 'Enrico Capobianco']
I am writing a research paper on a idea DAC-driven Integrative Network Regulation and Pathway Coordination in Breast Cancer.
[{"from": "human", "value": "I am writing a research paper on a idea DAC-driven Integrative Network Regulation and Pathway Coordination in Breast Cancer."}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Epigenetic variation represents a mechanism of regulation for genes expressed in different cancer histotypes.  considered breast cancer, and in- vestigated differential expression following treatment with the 5-Aza-2'- deoxycytidine or DAC, a demethylating agent. Several oncogenic signalling pathways altered upon DAC treatment re detected with significant enrich- ment, and a regulatory map integrating Transcription Factors and microRNAs was derived. The ultimate goal is deciphering the potential molecular mechan- isms induced by DAC therapy in MCF7 cells."}]