Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Correlated motif covering (CMC) is the problem of finding a set of motif pairs, i.e., pairs of patterns, in the sequences of proteins from a protein-protein interaction network (PPI-network) that describe the interactions in the network as concisely as possible. In other words, a perfect solution for CMC would be a minimal set of motif pairs that describes the interaction behavior perfectly in the sense that two proteins from the network interact if and only if their sequences match a motif pair in the minimal set. ,  introduce and formally define CMC and show that it is closely related to the red-blue set cover (RBSC) problem and its ighted version (WRBSC)—both ll-known NP-hard problems for that there exist several algorithms with known approximation factor guarantees.  prove the hardness of approximation of CMC by providing an approximation factor preserving reduction from RBSC to CMC.  show the existence of a theoretical approximation algorithm for CMC by providing an approximation factor preserving reduction from CMC to WRBSC.  adapt the latter algorithm into a functional heuristic for CMC, called CMC-approx, and experimentally assess its performance and biological relevance. The implementation in Java can be found at >http://bioinformatics.uhasselt.be.
['Peter Boyen', 'Frank Neven', 'Dries Van Dyck', 'Felipe Leal Valentim', 'Aalt D. J. van Dijk']
I am writing a research paper on a idea Mining Minimal Motif Pair Sets Maximally Covering Interactions in a Protein-Protein Interaction Network
[{"from": "human", "value": "I am writing a research paper on a idea Mining Minimal Motif Pair Sets Maximally Covering Interactions in a Protein-Protein Interaction Network"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Correlated motif covering (CMC) is the problem of finding a set of motif pairs, i.e., pairs of patterns, in the sequences of proteins from a protein-protein interaction network (PPI-network) that describe the interactions in the network as concisely as possible. In other words, a perfect solution for CMC would be a minimal set of motif pairs that describes the interaction behavior perfectly in the sense that two proteins from the network interact if and only if their sequences match a motif pair in the minimal set. ,  introduce and formally define CMC and show that it is closely related to the red-blue set cover (RBSC) problem and its ighted version (WRBSC)\u2014both ll-known NP-hard problems for that there exist several algorithms with known approximation factor guarantees.  prove the hardness of approximation of CMC by providing an approximation factor preserving reduction from RBSC to CMC.  show the existence of a theoretical approximation algorithm for CMC by providing an approximation factor preserving reduction from CMC to WRBSC.  adapt the latter algorithm into a functional heuristic for CMC, called CMC-approx, and experimentally assess its performance and biological relevance. The implementation in Java can be found at >http://bioinformatics.uhasselt.be."}]