Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: The University of Minnesota pathway prediction sys- tem (UM-PPS, http://umbbd.msi.umn.edu/predict/) recognizes functional groups in organic compounds that are potential targets of microbial catabolic reac- tions, and predicts transformations of these groups based on biotransformation rules. Rules are based on the University of Minnesota biocatalysis/biode- gradation database (http://umbbd.msi.umn.edu/) and the scientific literature. As rules re added to the UM-PPS, more of them re triggered at each prediction step. The resulting combinatorial explo- sion is being addressed in four ways. Biodegradation experts give each rule an aerobic likelihood value of Very Likely, Likely, Neutral, Unlikely or Very Unli- kely. Users now can choose whether they view all, or only the more aerobically likely, predicted trans- formations. Relative reasoning, allowing triggering of some rules to inhibit triggering of others, was implemented. Rules re initially assigned to indivi- dual chemical reactions. In selected cases, these have been replaced by super rules, which include two or more contiguous reactions that form a small pathway of their own. Rules are continually modified to improve the prediction accuracy; increasing rule stringency can improve predictions and reduce extraneous choices. The UM-PPS is freely available to all without registration. Its value to the scientific community, for academic, industrial and government use, is good and will only increase.
['Lynda B. M. Ellis', 'Junfeng Gao', 'Kathrin Fenner', 'Lawrence P. Wackett']
I am writing a research paper on a idea The University of Minnesota pathway prediction system: predicting metabolic logic
[{"from": "human", "value": "I am writing a research paper on a idea The University of Minnesota pathway prediction system: predicting metabolic logic"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: The University of Minnesota pathway prediction sys- tem (UM-PPS, http://umbbd.msi.umn.edu/predict/) recognizes functional groups in organic compounds that are potential targets of microbial catabolic reac- tions, and predicts transformations of these groups based on biotransformation rules. Rules are based on the University of Minnesota biocatalysis/biode- gradation database (http://umbbd.msi.umn.edu/) and the scientific literature. As rules re added to the UM-PPS, more of them re triggered at each prediction step. The resulting combinatorial explo- sion is being addressed in four ways. Biodegradation experts give each rule an aerobic likelihood value of Very Likely, Likely, Neutral, Unlikely or Very Unli- kely. Users now can choose whether they view all, or only the more aerobically likely, predicted trans- formations. Relative reasoning, allowing triggering of some rules to inhibit triggering of others, was implemented. Rules re initially assigned to indivi- dual chemical reactions. In selected cases, these have been replaced by super rules, which include two or more contiguous reactions that form a small pathway of their own. Rules are continually modified to improve the prediction accuracy; increasing rule stringency can improve predictions and reduce extraneous choices. The UM-PPS is freely available to all without registration. Its value to the scientific community, for academic, industrial and government use, is good and will only increase."}]