Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Background#R##N#Massive gene expression changes in different cellular states measured by microarrays, in fact, reflect just an "echo" of real molecular processes in the cells. Transcription factors constitute a class of the regulatory molecules that typically require posttranscriptional modifications or ligand binding in order to exert their function. Therefore, such important functional changes of transcription factors are not directly visible in the microarray experiments.
['Alexander E. Kel', 'Nico Voss', 'Ruy Jáuregui', 'Olga V. Kel-Margoulis', 'Edgar Wingender']
I am writing a research paper on a idea Beyond microarrays: Finding key transcription factors controlling signal transduction pathways
[{"from": "human", "value": "I am writing a research paper on a idea Beyond microarrays: Finding key transcription factors controlling signal transduction pathways"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Background#R##N#Massive gene expression changes in different cellular states measured by microarrays, in fact, reflect just an \"echo\" of real molecular processes in the cells. Transcription factors constitute a class of the regulatory molecules that typically require posttranscriptional modifications or ligand binding in order to exert their function. Therefore, such important functional changes of transcription factors are not directly visible in the microarray experiments."}]