Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Summary: Diffusion maps are a spectral method for non-linear dimension reduction and have recently been adapted for the visualization of single cell expression data. Here  present destiny, an efficient R implementation of the diffusion map algorithm. Our package includes a single-cell specific noise model allowing for missing and censored values. In contrast to previous implementations,  further present an efficient nearest-neighbour approximation that allows for the processing of hundreds of thousands of cells and a functionality for projecting new data on existing diffusion maps.  exemplarily apply destiny to a recent time-resolved mass cytometry dataset of cellular reprogramming. Availability and implementation: destiny is an open-source
['Philipp Angerer', 'Laleh Haghverdi', 'Maren Büttner', 'Fabian J. Theis', 'Carsten Marr', 'Florian Buettner']
I am writing a research paper on a idea destiny: diffusion maps for large-scale single-cell data in R
[{"from": "human", "value": "I am writing a research paper on a idea destiny: diffusion maps for large-scale single-cell data in R"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Summary: Diffusion maps are a spectral method for non-linear dimension reduction and have recently been adapted for the visualization of single cell expression data. Here  present destiny, an efficient R implementation of the diffusion map algorithm. Our package includes a single-cell specific noise model allowing for missing and censored values. In contrast to previous implementations,  further present an efficient nearest-neighbour approximation that allows for the processing of hundreds of thousands of cells and a functionality for projecting new data on existing diffusion maps.  exemplarily apply destiny to a recent time-resolved mass cytometry dataset of cellular reprogramming. Availability and implementation: destiny is an open-source"}]