Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Background#R##N#Translational por is the cellular rate of protein synthesis normalized to the biomass invested in translational machinery. Published data suggest a previously unrecognized pattern: translational por is higher among rapidly growing microbes, and lor among slowly growing microbes. One factor known to affect translational por is biased use of synonymous codons. The correlation within an organism beten expression level and degree of codon bias among genes of Escherichia coli and other bacteria capable of rapid growth is commonly attributed to selection for high translational por. Conversely, the absence of such a correlation in some slowly growing microbes has been interpreted as the absence of selection for translational por. Because codon bias caused by translational selection varies beten rapidly growing and slowly growing microbes,  investigated whether observed differences in translational por among microbes could be explained entirely by differences in the degree of codon bias. Although the data are not available to estimate the effect of codon bias in other species,  developed an empirically-based mathematical model to compare the translation rate of E. coli to the translation rate of a hypothetical strain which differs from E. coli only by lacking codon bias.
['Les Dethlefsen', 'Thomas M. Schmidt']
I am writing a research paper on a idea Differences in codon bias cannot explain differences in translational power among microbes.
[{"from": "human", "value": "I am writing a research paper on a idea Differences in codon bias cannot explain differences in translational power among microbes."}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Background#R##N#Translational por is the cellular rate of protein synthesis normalized to the biomass invested in translational machinery. Published data suggest a previously unrecognized pattern: translational por is higher among rapidly growing microbes, and lor among slowly growing microbes. One factor known to affect translational por is biased use of synonymous codons. The correlation within an organism beten expression level and degree of codon bias among genes of Escherichia coli and other bacteria capable of rapid growth is commonly attributed to selection for high translational por. Conversely, the absence of such a correlation in some slowly growing microbes has been interpreted as the absence of selection for translational por. Because codon bias caused by translational selection varies beten rapidly growing and slowly growing microbes,  investigated whether observed differences in translational por among microbes could be explained entirely by differences in the degree of codon bias. Although the data are not available to estimate the effect of codon bias in other species,  developed an empirically-based mathematical model to compare the translation rate of E. coli to the translation rate of a hypothetical strain which differs from E. coli only by lacking codon bias."}]