Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: In contrast-enhanced CE breast imaging, lesion contrast agent content may be diagnostic, relating to vascularization and tumour angiogenesis. Hover, factors in CE digital breast tomosynthesis DBT such as incomplete angular sampling, beam hardening and scatter can confound quantitative measurement.  propose system calibration to improve CEDBT quantitative potential. Fifteen projection images of an iodine calibration phantom, with various breast-equivalent compositions, thicknesses and lesion locations, re acquired over 40i¾?, and reconstructed using SART. A separate breast-equivalent phantom with iodinated spherical lesions was imaged to test quantification accuracy. Excellent linearity beten voxel signal and iodine concentration was achieved in the calibration data. In test phantom cases, lesion signal faithfully represented the true iodine concentration, but with wide confidence intervals for small lesions. While promising, it remains to be determined whether the iodine quantification accuracy is sufficient for lesion differentiation, and whether lesion shape, position, and non-uniform breast tissue would impair this estimation.
['Melissa L. Hill', 'James G. Mainprize', 'Martin J. Yaffe']
I am writing a research paper on a idea System Calibration for Quantitative Contrast-Enhanced Digital Breast Tomosynthesis CEDBT
[{"from": "human", "value": "I am writing a research paper on a idea System Calibration for Quantitative Contrast-Enhanced Digital Breast Tomosynthesis CEDBT"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: In contrast-enhanced CE breast imaging, lesion contrast agent content may be diagnostic, relating to vascularization and tumour angiogenesis. Hover, factors in CE digital breast tomosynthesis DBT such as incomplete angular sampling, beam hardening and scatter can confound quantitative measurement.  propose system calibration to improve CEDBT quantitative potential. Fifteen projection images of an iodine calibration phantom, with various breast-equivalent compositions, thicknesses and lesion locations, re acquired over 40i\u00be?, and reconstructed using SART. A separate breast-equivalent phantom with iodinated spherical lesions was imaged to test quantification accuracy. Excellent linearity beten voxel signal and iodine concentration was achieved in the calibration data. In test phantom cases, lesion signal faithfully represented the true iodine concentration, but with wide confidence intervals for small lesions. While promising, it remains to be determined whether the iodine quantification accuracy is sufficient for lesion differentiation, and whether lesion shape, position, and non-uniform breast tissue would impair this estimation."}]