Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Recent findings suggest that contact stress is a potent predictor of subsequent symptomatic osteoarthritis development in the knee. Hover, much larger numbers of knees (likely on the order of hundreds, if not thousands) need to be reliably analyzed to achieve the statistical por necessary to clarify this relationship. This study assessed the reliability of new semiautomated computational methods for estimating contact stress in knees from large population-based cohorts. Ten knees of subjects from the Multicenter Osteoarthritis Study re included. Bone surfaces re manually segmented from sequential 1.0 Tesla magnetic resonance imaging slices by three individuals on two nonconsecutive days. Four individuals then registered the resulting bone surfaces to corresponding bone edges on ight-bearing radiographs, using a semi-automated algorithm. Discrete element analysis methods re used to estimate contact stress distributions for each knee. Segmentation and registration reliabilities (day-to-day and interrater) for peak and mean medial and lateral tibiofemoral contact stress re assessed with Shrout-Fleiss intraclass correlation coefficients (ICCs). The segmentation and registration steps of the modeling approach re found to have excellent day-to-day (ICC 0.93–0.99) and good inter-rater reliability (0.84–0.97). This approach for estimating compartment-specific tibiofemoral contact stress appears to be sufficiently reliable for use in large population-based cohorts.
['Donald D. Anderson', 'Neil A. Segal', 'Andrew M. Kern', 'Michael C. Nevitt', 'James C. Torner', 'J.A. Lynch']
I am writing a research paper on a idea Reliability of Semiautomated Computational Methods for Estimating Tibiofemoral Contact Stress in the Multicenter Osteoarthritis Study
[{"from": "human", "value": "I am writing a research paper on a idea Reliability of Semiautomated Computational Methods for Estimating Tibiofemoral Contact Stress in the Multicenter Osteoarthritis Study"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Recent findings suggest that contact stress is a potent predictor of subsequent symptomatic osteoarthritis development in the knee. Hover, much larger numbers of knees (likely on the order of hundreds, if not thousands) need to be reliably analyzed to achieve the statistical por necessary to clarify this relationship. This study assessed the reliability of new semiautomated computational methods for estimating contact stress in knees from large population-based cohorts. Ten knees of subjects from the Multicenter Osteoarthritis Study re included. Bone surfaces re manually segmented from sequential 1.0 Tesla magnetic resonance imaging slices by three individuals on two nonconsecutive days. Four individuals then registered the resulting bone surfaces to corresponding bone edges on ight-bearing radiographs, using a semi-automated algorithm. Discrete element analysis methods re used to estimate contact stress distributions for each knee. Segmentation and registration reliabilities (day-to-day and interrater) for peak and mean medial and lateral tibiofemoral contact stress re assessed with Shrout-Fleiss intraclass correlation coefficients (ICCs). The segmentation and registration steps of the modeling approach re found to have excellent day-to-day (ICC 0.93\u20130.99) and good inter-rater reliability (0.84\u20130.97). This approach for estimating compartment-specific tibiofemoral contact stress appears to be sufficiently reliable for use in large population-based cohorts."}]