Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Comparing protein structures in three dimensions is a computationally expensive process that makes a full scan of a protein against a library of known protein structures impractical. To reduce the cost,  can use an approximation of the three dimensional structure that allows protein comparison to be performed quickly to filter away dissimilar proteins.   present a new algorithm, called SCALE, for protein structure comparison. In SCALE, a protein is represented as a sequence of secondary structure elements (SSEs) augmented with 3D structural properties such as the distances and angles beten the SSEs. As such, the comparison beten two proteins is reduced to a sequence alignment problem beten their corresponding sequences of SSEs. The 3-D structural properties of the proteins contribute to the similarity score beten the two sequences.  have implemented SCALE, and compared its performance against existing schemes. Our performance study shows that SCALE outperforms existing methods in terms of both efficiency and effectiveness (measured in terms of precision and recall).
['Chern-Hooi Chionh', 'Zhiyong Huang', 'Kian-Lee Tan', 'Zhen Yao']
I am writing a research paper on a idea Augmenting SSEs with structural properties for rapid protein structure comparison
[{"from": "human", "value": "I am writing a research paper on a idea Augmenting SSEs with structural properties for rapid protein structure comparison"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely: Comparing protein structures in three dimensions is a computationally expensive process that makes a full scan of a protein against a library of known protein structures impractical. To reduce the cost,  can use an approximation of the three dimensional structure that allows protein comparison to be performed quickly to filter away dissimilar proteins.   present a new algorithm, called SCALE, for protein structure comparison. In SCALE, a protein is represented as a sequence of secondary structure elements (SSEs) augmented with 3D structural properties such as the distances and angles beten the SSEs. As such, the comparison beten two proteins is reduced to a sequence alignment problem beten their corresponding sequences of SSEs. The 3-D structural properties of the proteins contribute to the similarity score beten the two sequences.  have implemented SCALE, and compared its performance against existing schemes. Our performance study shows that SCALE outperforms existing methods in terms of both efficiency and effectiveness (measured in terms of precision and recall)."}]