Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely:  investigate a novel approach for studying protein folding that has evolved from robotics motion planning techniques called probabilistic roadmap methods (prms). Our focus is to study issues related to the folding process, such as the formation of secondary and tertiary structure, assuming  know the native fold. A feature of our prm-based framework is that the large sets of folding pathways in the roadmaps it produces, in a few hours on a desktop PC, provide global information about the protein’s energy landscape. This is an advantage over other simulation methods such as molecular dynamics or Monte Carlo methods which require more computation and produce only a single trajectory in each run. In our initial studies,  obtained encouraging results for several small proteins. ,  investigate more sophisticated techniques for analyzing the folding pathways in our roadmaps. In addition to more formally revalidating our previous results,  present a case study showing our technique captures known folding dierences beten the structurally similar proteins G and L.
['Guang Song', 'Shawna L. Thomas', 'Ken A. Dill', 'J. Martin Scholtz', 'Nancy M. Amato']
I am writing a research paper on a idea A PATH PLANNING-BASED STUDY OF PROTEIN FOLDING WITH A CASE STUDY OF HAIRPIN FORMATION IN PROTEIN G AND L
[{"from": "human", "value": "I am writing a research paper on a idea A PATH PLANNING-BASED STUDY OF PROTEIN FOLDING WITH A CASE STUDY OF HAIRPIN FORMATION IN PROTEIN G AND L"}, {"from": "gpt", "value": "Thats a unique idea.You should consider the following idea to enhance your idea so that it would impact uniquely:  investigate a novel approach for studying protein folding that has evolved from robotics motion planning techniques called probabilistic roadmap methods (prms). Our focus is to study issues related to the folding process, such as the formation of secondary and tertiary structure, assuming  know the native fold. A feature of our prm-based framework is that the large sets of folding pathways in the roadmaps it produces, in a few hours on a desktop PC, provide global information about the protein\u2019s energy landscape. This is an advantage over other simulation methods such as molecular dynamics or Monte Carlo methods which require more computation and produce only a single trajectory in each run. In our initial studies,  obtained encouraging results for several small proteins. ,  investigate more sophisticated techniques for analyzing the folding pathways in our roadmaps. In addition to more formally revalidating our previous results,  present a case study showing our technique captures known folding dierences beten the structurally similar proteins G and L."}]