След прилагане на пегфилграстим се съобщава за чести (≥ 1/ 100 до < 1/ 10), но като цяло йт
Common (≥ 1/ 100 to < 1/ 10) but generally asymptomatic cases of splenomegaly and very rare cases of splenic rupture, including some fatal cases, have been reported following administration of