Активността на основните метаболити е около 5- 6 и 3 пъти по- слаба отколкото на натеглинид, съответно.
The main metabolites found in humans result from hydroxylation of the isopropyl side-chain, either on the methine carbon, or one of the methyl groups; activity of the main metabolites is about 5– 6 and 3 times less potent than nateglinide, respectively.