39 да бъде намалена с 0, 4 mg/ m2 на ден до 1, 9 mg/ m2 на ден (която впоследствие да бъде намалена до 1, 5 mg/ m2 на ден при необходимост).
If dose reduction is chosen for patients who experience severe neutropenia (neutrophil count < 0.5 x 109/ l) for 7 days or more, or severe neutropenia associated with fever or infection, or who have had treatment delayed due to neutropenia, the dose should be reduced by 0.4 mg/ m2/ day to 36 1.9 mg/ m2/ day (or subsequently down to 1.5 mg/ m2/ day if necessary).