Остро влошаване на бъбречната функция може да доведе до неочаквано кумулиране на ротиготин (вж. точки 4. 2 и 5. 2).
If application site reactions occur which last for more than a few days or are persistent, if there is an increase in severity, or if the skin reaction spreads outside the application site, an assessment of the risk/ benefit balance for the individual patient should be conducted.