санн е тз пим ж т, а л рнъ е еу иа (18, 9 се 27, 3 l/ чс В п еитв, рвеи с ои р ъ ее киъ ст рдц рн п о и ъ нбзпсот а лнаи (5- 20 mg) е рв и м ж у
40 In smoking subjects with mild hepatic dysfunction, mean elimination half-life (39.3 hr) was prolonged and clearance (18.0 l/ hr) was reduced analogous to non-smoking healthy subjects (48.8 hr and 14.1 l/ hr, respectively).