Cmax, ss 12, 2±6, 2 ng/ ml, tmax, ss 3, 01±2, 40h, AUCτ, ss 158±70 ng• h/ ml, CL/ F/ W 182±72 ml/ h/ kg (параметри, изчислени от резултатите от LC- MS/ MS хроматографския анализ).
Pharmacokinetic parameters for sirolimus obtained from 19 renal transplant patients receiving microemulsion ciclosporin (4 hours prior to Rapamune) and corticosteroids, following daily doses of 2 mg Rapamune solution in a phase III clinical trial, were; Cmax, ss 12.2 6.2 ng/ ml, tmax, ss 3.01  2.40h, AUC, ss 158  70 ng h/ ml, CL/ F/ W 182 72 ml/ h/ kg (parameters calculated from LC-MS/ MS assay results).