Съобщава се за панкреатит (фатален и не - фатален) и периферна невропатия При инфектирани с HIV пациенти, получаващи ставудин в комбинация с хидроксиурея и диданозин.
Hepatotoxicity and hepatic failure resulting in death were reported during postmarketing surveillance in HIV infected patients treated with antiretroviral agents and hydroxyurea; fatal hepatic events were reported most often in patients treated with stavudine, hydroxyurea and didanosine.