* - p ≤ 0, 0001, tocilizumab vs. placebo + MTX ** - p < 0, 005, tocilizumab vs. placebo + MTX
JSN - Joint Space Narrowing, restringimento dello spazio articolare * - p ≤ 0,0001; TCZ vs PBO + MTX ** - p < 0,005; TCZ vs PBO + MTX