30% af kalorierne stammer fra fedtstoffer (svarende til < 67 g fedt, hvis kosten indeholder 2000 kcal/ døgn).
While taking orlistat, the patient should be on a nutritionally balanced, mildly hypocaloric diet that contains approximately 30% of calories from fat (e. g. in a 2,000 kcal/ day diet, this equates to < 67 g of fat).