Absorption Efter oral administration af en 100 mg dosis til raske personer absorberedes sitagliptin hurtigt, med peak- plasmakoncentrationer (median Tmax) 1- 4 timer efter dosering, gennemsnitlig plasma- AUC for sitagliptin var 8, 52 µM• hr, Cmax var 950 nM.
Absorption Following oral administration of a 100-mg dose to healthy subjects, sitagliptin was rapidly absorbed, with peak plasma concentrations (median Tmax) occurring 1 to 4 hours post-dose, mean plasma AUC of sitagliptin was 8.52 μ M• hr, Cmax was 950 nM.