Plasmaindholdet af lasofoxifen var omtrent det samme hos raske frivillige som hos frivillige med mild leverinsufficiens (Child- Pugh Class A) og moderat øget (38%) hos frivillige med moderat leverinsufficiens (Child- Pugh Class B) sammenlignet med raske frivillige.
Plasma lasofoxifene exposure was approximately the same in healthy subjects as in subjects with mild hepatic impairment (Child-Pugh Class A) and was modestly increased (38%) in subjects with moderate hepatic impairment (Child-Pugh Class B) compared to healthy subjects.