Patienter, som får krampestillende medicin, der primært metaboliseres i leveren, som f. eks. phenytoin, carbamazepin og phenobarbital, kan have brug for periodisk monitorering af plasmakoncentrationerne.
Patients who are receiving concomitant anticonvulsant medicinal products primarily metabolised by the liver, such as phenytoin, carbamazepine and phenobarbital, may require periodic monitoring of plasma levels.