Paranoide idéer kan forstærkes. – Når den depressive fase ved bipolar lidelse behandles, kan den ændre sig til manisk fase.
Like with other antidepressants, the following should be taken into account: – Worsening of psychotic symptoms can occur when antidepressants are administered to patients with schizophrenia or other psychotic disturbances; paranoid thoughts can be intensified. – When the depressive phase of bipolar disorder is being treated, it can transform into the manic phase.