Pravastatin metaboliseres ikke signifikant ved cytokrom P450, ej heller synes det at være et substrat eller en inhibitor af P- glycoprotein men snarere et substrat af andre transportproteiner.
Pravastatin is not significantly metabolised by cytochrome P450 nor does it appear to be a substrate or an inhibitor of P-glycoprotein but rather a substrate of other transport proteins.