Der bør tages passende forholdsregler, og seponering af behandlingen med parecoxib bør overvejes, hvis der ses forværring af specifikke kliniske symptomer hos disse patienter (se pkt.
Appropriate measures should be taken and discontinuation of parecoxib therapy should be considered if there is clinical evidence of deterioration in the condition of specific clinical symptoms in these patients (see section 5.1).