In vivo aktivitet over for HCMV blev bekræftet i kontrollerede kliniske undersøgelser af cidofovir, hvor AIDS- patienter med CMV- retinitis blev behandlet.
In vivo activity against HCMV was confirmed with controlled clinical studies of cidofovir for the treatment of CMV retinitis in patients with AIDS, which demonstrated statistically significant delays in time to CMV retinitis progression for patients on cidofovir when compared to control patients.