Rifabutin: når rifabutin og Kaletra gives samtidig i 10 dage, stiger rifabutin (modersubstansen og den aktive 25- O- desacetyl metabolit) Cmax og AUC henholdsvis 3, 5 - gange og 5, 7 - gange.
Rifabutin: when rifabutin and Kaletra were co-administered for 10 days, rifabutin (parent substance and active 25-O-desacetyl metabolite) Cmax and AUC were increased by 3.5- and 5.7-fold, respectively.