Hos mennesker stimulerer gemfibrozil den perifere lipolyse af triglyceridrige lipoproteiner såsom lipoproteiner med meget lav densitet (VLDL) og chylomikroner (ved at stimulere lipoproteinlipasen, LPL).
In man, gemfibrozil stimulates the peripheral lipolysis of triglyceride rich lipoproteins such as very low-density lipoproteins (VLDL) and chylomicrons (by stimulation of the lipoprotein lipase, LPL).