Det andet aktive stof i Irbesartan Hydrochlorothiazide BMS (hydrochlorthiazid) har i sjældne tilfælde været forbundet med mere alvorlige bivirkninger:
The other component of Irbesartan Hydrochlorothiazide BMS (hydrochlorothiazide) has been associated rarely with other more serious side effects mainly affecting the blood, the skin or the kidneys.