Anakinra hæmmer de reaktioner som IL- 1 fremkalder in vitro, inklusiv induktionen af nitrit oxid samt prostaglandin E2 og/ eller kollagenase produktionen af synovial cellerne, fibroblaster og kondrocytter.
Anakinra inhibits responses elicited by IL-1 in vitro, including the induction of nitric oxide and prostaglandin E2 and/ or collagenase production by synovial cells, fibroblasts, and chondrocytes.