De mest almindeligt observerede bivirkninger forbundet med anvendelse af thalidomid kombineret med melphalan og prednison er: neutropeni, leukopeni, obstipation, somnolens, paræstesi, perifer neuropati, anæmi, lymfopeni, trombocytopeni, svimmelhed, dysæstesi, tremor og perifert ødem.
The most commonly observed adverse reactions associated with the use of thalidomide in combination with melphalan and prednisone are: neutropenia, leukopenia, constipation, somnolence, paraesthesia, peripheral neuropathy, anaemia, lymphopenia, thrombocytopenia, dizziness, dysaesthesia, tremor and peripheral oedema.