Dog viste to individer med Child- Pugh score på 8 og 9 en stigning i systemisk eksponering som var mindst fordoblet sammenlignet med individer med lavere Child- Pugh score.
However, two subjects with Child-Pugh scores of 8 and 9 showed an increase in systemic exposure of at least 2-fold compared to subjects with lower Child-Pugh scores.