Krydsresistens er hovedsagligt forbundet med effluxpumper, der giver resistens til β- lactamer, quinoloner og tetracycliner afhængigt af pumpens specificitet med ens substrat.
Cross-resistance is mainly linked with efflux pumps which confer resistance to β -lactams, quinolones and tetracyclines depending on the specificity of the pump with its substrate.