Behandlingen bør seponeres i tilfælde af symptomatisk hyperlaktatæmi og metabolisk/ lactacidosis, progressiv hepatomegali eller hurtigt stigende aminotransferaseniveauer.
Treatment with NRTIs should be discontinued if there is symptomatic hyperlactatemia and metabolic/ lactic acidosis, progressive hepatomegaly, or rapidly elevating aminotransferase levels.