I et 5- årigt studie med postmenopausale kvinder (PROOF- studiet), medførte administration af 200 IE intranasalt lakse calcitonin en reduktion på 33% i den relative risiko for at udvikle vertebrale frakturer.
23/ 30 In a 5-year trial in postmenopausal women (PROOF study), administration of 200 IU intranasal salmon calcitonin resulted in a reduction of 33% in the relative risk of developing vertebral fractures.