Thiazider, herunder hydrochlorthiazid, kan forårsage forstyrrelser i væske - eller elektrolytbalancen (bl. a. hypokaliæmi, hyponatriæmi og hypochloræmisk alkalose).
Thiazides, including hydrochlorothiazide, can cause fluid or electrolyte imbalance (including hypokalaemia, hyponatraemia, and hypochloraemic alkalosis).