dosis ikke overstige 40 mg dagligt for patienter, der samtidig får diltiazem, med mindre den kliniske fordel kan opveje den forøgede risiko for myopati og rhabdomyolyse.
Therefore, the dose of simvastatin should not exceed 40 mg daily in patients receiving concomitant medication with diltiazem, unless the clinical benefit is likely to outweigh the increased risk of myopathy and rhabdomyolysis.