Losartan er en oralt aktiv angiotensin II (Ang- II) receptor- antagonist, der virker på AT1- receptor- undertypen og dermed blokerer for virkning af Ang- II i renin- angiotensin- systemets (RAS) kaskade.
Losartan is an orally active angiotensin II (Ang- II) receptor antagonist acting on the AT1 receptor subtype, thus blocking the effect of Ang-II in the renin angiotensin system (RAS) cascade.