Artralgi, myalgi, rygsmerte (især unge patienter) Arthritis, calcinosis (kalcifikation af ligamenter og sener), tidlig lukning af epifyserne, eksostose, (hyperostose), nedsat knogletæthed, tendonitis
Arthralgia, Myalgia, Back pain (particularly adolescent patients) Arthritis, Calcinosis (calcification of ligaments and tendons), Epiphyses premature fusion, Exostosis, (hyperostosis), Reduced bone density, Tendonitis