Da montelukast metaboliseres via CYP3A4, bør der, især hos børn, udvises forsigtighed, når montelukast administreres samtidig med CYP3A4- induktorer, som phenytoin, phenobarbital og rifampicin.
Since montelukast is metabolised by CYP 3A4, caution should be exercised, particularly in children, when montelukast is coadministered with inducers of CYP 3A4, such as phenytoin, phenobarbital and rifampicin.