Hvis behandling med HMG- CoA- reduktasehæmmere er indiceret, anbefales behandling med pravastatin eller fluvastatin, fordi deres metabolisme ikke afhænger af CYP3A4 og der forventes ikke interaktioner med proteasehæmmere.
HMG-CoA reductase inhibitors: if treatment with a HMG-CoA reductase inhibitor is indicated, pravastatin or fluvastatin is recommended because their metabolism is not dependent on CYP 3A4 and interactions are not expected with protease inhibitors.