Alle patienter i studierne omhandlende kronisk hepatitis C fik foretaget en leverbiopsi før inklusion, men for specielle patienter (f. eks. patienter med genotype 2 eller 3) er behandling mulig uden histologisk bekræftelse.
All patients in the chronic hepatitis C studies had a liver biopsy before inclusion, but in certain cases (ie, patients with genotype 2 or 3), treatment may be possible without histological confirmation.