Der skal iagttages forsigtighed hos patienter med asymptomatisk venstre ventrikulær dysfunktion og hos patienter med hjerteinsufficiens NYHA- klasse II på grund af det begrænsede antal undersøgte patienter.
Caution is needed in patients with asymptomatic left ventricular dysfunction, as well as in heart failure patients with NYHA functional classification II due to a limited number of patients studied.