Det gør det muligt for methylnaltrexon at fungere som en perifert virkende my- opioidantagonist i væv såsom mave - tarmkanalen uden at hæmme de opioid- medierede analgetiske effekter på det centrale nervesystem.
This allows methylnaltrexone to function as a peripherally acting mu-opioid antagonist in tissues such as the gastrointestinal tract, without impacting opioid-mediated analgesic effects on the central nervous system.