I så fald skal ciclosporindosen nedtrappes helt over fire til otte uger, og Rapamunedosen skal øges, indtil der opnås sirolimusniveauer i blodet på ca.
In these cases, the dose of ciclosporin should be gradually reduced to zero over four to eight weeks, and the dose of Rapamune increased to obtain blood levels of sirolimus of about 12 to 20 ng/ ml.