5 Metoprolol Når metoprolol (et CYP2D6 substrat) blev administrret samtidig med Ketek, var der en let stigning på ca 38% af Cmax og af AUC for metoprolol, der var imidlerid ingen effekt på metoprolols eliminationshalveringstid.
5 Metoprolol When metoprolol (a CYP2D6 substrate) was coadministered with Ketek, metropolol Cmax and AUC were increased by approximately 38%, however, there was no effect on the elimination half-life of metoprolol.