Der blev set stigninger af ALAT/ ASAT til > 5 gange øvre referencegrænse hos 0, 7% af de patienter, der fik på tocilizumab monoterapi, og hos 1, 4% af de patienter, der fik tocilizumab plus DMARD.
Elevations of ALT/ AST > 5 x ULN were observed in 0.7% of tocilizumab monotherapy patients and 1.4% of tocilizumab plus DMARD patients, the majority of whom were discontinued permanently from tocilizumab treatment.