Halvdelen af de tilfælde, hvor stigningen oversteg 10 gange øvre referencegrænse, blev Pegasys- dosis reduceret eller seponeret, indtil transaminasestigningerne var forsvundet, hvorimod behandlingen fortsatte uændret i de resterende tilfælde.
In approximately half the case of flares exceeding 10 times the upper limit of normal, Pegasys dosing was reduced or withheld until the transaminase elevations subsided, while in the rest therapy was continued unchanged.