Baseret på det undersøgte område for hver variabel forventes bosentans farmakokinetik ikke at blive påvirket af køn, legemsvægt, race eller alder i den voksne population i væsentlig grad.
Based on the investigated range of each variable, it is not expected that the pharmacokinetics of bosentan will be influenced by gender, body weight, race, or age in the adult population to any relevant extent.