Efter mindst fire ugers behandling, og hvis denne dosis ifølge den behandlende læge tåles godt, bør dosis øges til 9, 5 mg/ 24 timer, som er den anbefalede virksomme dosis.
After a minimum of four weeks of treatment and if well tolerated according to the treating physician, this dose should be increased to 9.5 mg/ 24 h, which is the recommended effective dose.