Gruppe 1 Normalt sunde kontrolpersoner med en glomerulær filtrationshastighed på > 80 ml/ min. / 1, 73 m2 Gruppe 2 Mild nyreinsufficiens med en glomerulær filtrationshastighed på 40- 79 ml/ min. / 1, 73 m2
Group 1 Normal healthy controls with a glomerular filtration rate (GFR) of > 80 ml/ min/ 1.73 m2 Group 2 Mild renal insufficiency with a GFR of 40-79 ml/ min/ 1.73 m2 Group 3 Moderate/ marked renal insufficiency with a GFR 10-39 ml/ min/ 1.73 m2 Group 4 Severe renal insufficiency with a GFR < 10 ml/ min/ 1.73 m2 In each subgroup 10 subjects were included.