Den potentielle effekt af øgede plasmakoncentrationer af midazolam og andre benzodiazepiner, der metaboliseres via CYP3A4 (alprazolam, triazolam) bør tages i betragtning, når disse gives samtidigt med administration af et 3- dages (fos) aprepitantregime.
The potential effects of increased plasma concentrations of midazolam or other benzodiazepines metabolised via CYP3A4 (alprazolam, triazolam) should be considered when co-administering these agents with a 3-day regimen of fosaprepitant followed by aprepitant.