Forskellige neoplasier, omfattende brystcancer, keratoacanthom i huden og basalcelleadenom, fandtes i en undersøgelse omfattende 6- cycli på rotter, mens der ikke sås tumorer eller præneoplastiske forandringer i undersøgelser på hunde.
A variety of neoplasms, including mammary carcinomas, keratocanthoma of the skin and basal cell adenoma were observed in the 6-cycle rat study while no tumours or pre-neoplastic changes were evident in dog studies.