Fordeling Den gennemsnitlige distributionsvolumen (Vd) for bortezomib var 1659- 3294 l efter indgift af enkeltdoser eller gentagne doser på 1, 0 mg/ m2 eller 1, 3 mg/ m2 til patienter med myelomatose.
Distribution The mean distribution volume (Vd) of bortezomib ranged from 1659 l to 3294 l following single- or repeated-dose administration of 1.0 mg/ m2 or 1.3 mg/ m2 to patients with multiple myeloma.