In vitro- undersøgelser har påvist, at CYP2C8 og 3A4 er involveret i dannelsen af henholdsvis 6 alpha- hydroxypaclitaxel og 3 ’ - para- hydroxypaclitaxel.
In vitro studies have shown that CYP2C8 and 3A4 are involved in the formation of 6 alpha-hydroxypaclitaxel and 3’ -para-dihydroxypaclitaxel, respectively.