I et interaktionsstudie hos raske, frivillige forsøgspersoner ændrede entakapon imidlertid ikke plasmaniveauerne for S- warfarin, mens AUC for R- warfarin øgedes i gennemsnit med 18% [CI90 11 - 26%].
However, in an interaction study with healthy volunteers, entacapone did not change the plasma levels of S-warfarin, while the AUC for R-warfarin increased on average by 18% [CI90 11- 26%].