N- desethyl- brinzolamid RBC- koncentrationerne voksede, og total RBC CA aktivitet aftog med faldende cratinin clearance, mens brinzolamid RBC koncentrationerne og CA- II forblev uforandrede.
N-desethyl-brinzolamide RBC concentrations increased and total RBC CA activity decreased with decreasing creatinine clearance but brinzolamide RBC concentrations and CA-II activity remained unchanged.