In vitro - og in vivo - forsøg viser, at venlafaxin metaboliseres til en underordnet, mindre aktiv metabolit, N- desmethylvenlafaxin, af CYP3A4.
In vitro and in vivo studies indicate that venlafaxine is metabolised to a minor, less active metabolite, N-desmethylvenlafaxine, by CYP3A4.