Som forventet, udfra hormonets heterologe sammensætning, resulterede lutropin alfa i et antistof respons hos forsøgsdyr hvilket reducerede det målelige niveau af serum LH, men forhindrede ikke helt den biologiske aktivitet.
As expected from the heterologous protein nature of the hormone, lutropin alfa raised an antibody response in experimental animals after a period that reduced the measurable serum LH levels but did not fully prevent its biological action.