De alvorlige bivirkninger, der kunne henføres til TRISENOX, inkluderede APL - differentieringssyndrom (3), leukocytose (3), forlænget QT- interval (4, 1 med torsade de pointes), atrieflimmer/ atrieflagren (1), hyperglykæmi (2) og en række forskellige alvorlige bivirkninger i relation til blødninger, infektioner, smerte, diarré, kvalme.
Those serious adverse reactions attributed to TRISENOX included APL differentiation syndrome (3), leukocytosis (3), prolonged QT interval (4, 1 with torsade de pointes), atrial fibrillation/ atrial flutter (1), hyperglycaemia (2) and a variety of serious adverse reactions related to haemorrhage, infections, pain, diarrhoea, nausea.