Hos patienter med atopisk dermatitis var bedringen af hudlæsioner under salvebehandling med tacrolimus ledsaget at reduceret Fc receptor expression på Langerhanske celler og en reduktion af deres hyperstimulerende effekt på T- celler.
In patients with atopic dermatitis, improvement of skin lesions during treatment with tacrolimus ointment was associated with reduced Fc receptor expression on Langerhans cells and a reduction of their hyperstimulatory activity towards T cells.