Effekten og bivirkninger af tricykliske antidepressiva bør overvåges omhyggeligt, når disse (f. eks. desipramin og nortriptylin) anvendes samtidig med Agenerase (se afsnit 4. 4).
Tricyclic antidepressants: careful monitoring of the therapeutic and adverse reactions of tricyclic antidepressants is recommended when they (for example desipramine and nortriptyline) are concomitantly administered with Agenerase (see section 4.4).