Der tilrådes forsigtighed, når bisfosfonater indgives sammen med aminoglykosider, da begge stoffer kan have en additiv effekt og give et lavere serumcalciumniveau i længere perioder end påkrævet.
Caution is advised when bisphosphonates are administered with aminoglycosides, since both agents may have an additive effect, resulting in a lower serum calcium level for longer periods than required.