Hos patienter med rheumatoid arthritis havde celecoxib ingen signifikant effekt på farmakokinetikken (plasma - eller renal clearence) af methotrexat (i reumatologiske doser).
In patients with rheumatoid arthritis celecoxib had no statistically significant effect on the pharmacokinetics (plasma or renal clearance) of methotrexate (in rheumatologic doses).