Lokale reaktioner inklusiv myositis og granulomatom ved injektionsstedet blev tilskrevet vehiklet, men sværhedsgraden af myositis hos kaniner steg i takt med fulvestrant i forhold til saltkontrollen.
Local reactions, including myositis and granulomatoma at the injection site were attributed to the vehicle but the severity of myositis in rabbits increased with fulvestrant, compared to the saline control.