4500 patienter uden primært mavesår bekræftet ved øvre gastroskopi (celecoxibdoser på 50- 400 mg 2 gange daglig).
Five randomised double-blind controlled studies have been conducted including scheduled upper gastrointestinal endoscopy in approximately 4500 patients free from initial ulceration (celecoxib doses from 50 mg-400 mg BID).