De føtale misdannelser efter eksponering for isotretinoin omfatter abnormaliteter i centralnervesystemet (hydrocephalus, cerebellare misdannelser/ abnormaliteter, microcephali), deformitet af ansigtet, ganespalte, abnormaliteter af ydre øre (fravær af ydre øre, små eller fraværende eksterne auditive kanaler), øjeabnormaliteter (microphthalmia), kardiovaskulære abnormaliteter (conotruncale misdannelser som fx Steno- Fallot´s tetrade, ændringer af de store kar, septumdefekter), abnormaliteter af thymus og parathyroideae.
The foetal malformations associated with exposure to isotretinoin include central nervous system abnormalities (hydrocephalus, cerebellar malformation/ abnormalities, microcephaly), facial dysmorphia, cleft palate, external ear abnormalities (absence of external ear, small or absent external auditory canals), eye abnormalities (microphthalmia), cardiovascular abnormalities (conotruncal malformations such as tetralogy of Fallot, transposition of great vessels, septal defects), thymus gland abnormality and parathyroid gland abnormalities.