Ingen NOTEL (No Observed Toxic Effect Level) kunne bestemmes i de prækliniske studier med undtagelse af en 7 dages administration af 0, 1 µg/ kg i aber.
No NOTEL (No Observed Toxic Effect Level) could be established in the preclinical studies with the exception of a 7 day administration of 0.1 µg/ kg in monkeys.