Europa- Kommissionen udstedte en markedsføringstilladelse med gyldighed i hele Den Europæiske Union for Advocate til Bayer HealthCare AG (tidligere navn Bayer AG) den 2. april 2003.
The European Commission granted a marketing authorisation valid throughout the European Union for Advocate to Bayer HealthCare AG (previously called Bayer AG) on 2 April 2003.