I fastende raske forsøgspersoner gav en opdeling af den totale daglige dosis (800 mg) på 200 mg fire gange dagligt sammenlignet med 400 mg to gange dagligt en 58% øget eksponering for posaconazol over 48 timer.
13 daily dose (800 mg) into 200 mg four times daily compared to 400 mg twice daily, was shown to increase posaconazole exposure by 58% over 48 hours.