Patienter behandlet med rituximab havde en signifikant større reduktion i sygdomsaktivitetsscore (DAS28) end patienter behandlet med methotrexat alene (gennemsnitlig ændring i DAS28 fra baseline var henholdsvis - 1, 9 versus - 0, 4; p < 0, 0001).
23 Rituximab treated patients had a significantly greater reduction in disease activity score (DAS28) than patients treated with methotrexate alone (Mean change in DAS28 from baseline -1.9 vs. -0.4, p < 0.0001, respectively).