Når angiotensin II- antagonister administreres samtidigt med NSAID (dvs. selektive COX- 2 hæmmere, acetylsalicylsyre i antiinflammatoriske doser og non- selektive NSAID) kan afsvækning af den antihypertensive virkning forekomme.
When angiotensin II antagonists are administered simultaneously with NSAIDs (i. e. selective COX-2 inhibitors, acetylsalicylic acid at anti-inflammatory doses and non-selective NSAIDs), attenuation of the antihypertensive effect may occur.