Artralgier, myalgier, rygsmerter (særligt hos yngre patienter) Artritis, calcinosis (forkalkninger af ligamenter og sener), epifyse præmatur fusion, exostosis, (hyperostosis), nedsat knogletæthed,
Arthralgia, Myalgia, Back pain (particularly adolescent patients) Arthritis, Calcinosis (calcification of ligaments and tendons), Epiphyses premature fusion, Exostosis, (hyperostosis), Reduced bone density, Tendonitis