Øget creatininfosfokinase (CPK), myalgia, myositis, og sjældent er rhabdomyolyse blevet rapporteret med proteasehæmmere og især i kombination med nukleosid revers transkriptasehæmmere.
Increased CPK, myalgia, myositis, and rarely, rhabdomyolysis have been reported with protease inhibitors, particularly in combination with nucleoside reverse transcriptase inhibitors.