Efter samtidig indgift af begge stoffer er set øget frekvens af omlagt navlearterie og ufuldstændig forbening af nakkebenet hos rotter ved doser, der typisk sættes i forbindelse med glukokortikoid- inducerede abnormiteter.
Following co-administration, increased incidences of transposed umbilical artery and incomplete ossification of occipital bone were found in rats at doses associated with known glucocorticoid-induced abnormalities.