Samtidig administration af aliskiren med enten valsartan (↓28%), metformin (↓28%), amlodipin (↑29%) eller cimetidin (↑19%) resulterede i en ændring af Cmax eller AUC for Enviage på mellem 20% og 30%.
Co-administration of aliskiren with either valsartan (↓ 28%), metformin (↓ 28%), amlodipine (↑ 29%) or cimetidine (↑ 19%) resulted in between 20% and 30% change in Cmax or AUC of Enviage.