Hos nyretransplanterede patienter med svær, kronisk nyreinsufficiens (glomerulær filtrationsrate < 25 ml• min- 1• 1, 73 m- 2), bortset fra den umiddelbare post - transplantationsperiode, skal doser på mere end 1 g administreret to gange daglig undgås.
Use in renal impairment: in renal transplant patients with severe chronic renal impairment (glomerular filtration rate < 25 ml• min-1• 1.73 m-2), outside the immediate post-transplant period, doses greater than 1 g administered twice a day should be avoided.