Det kan ikke anbefales at benytte Protopy salve til patienter med genetisk epidermale barrieredefekter som Netherton' s syndrome på grund af potentialet for permanent øget systemisk absorption af tacrolimus.
The use of Protopy ointment in patients with genetic epidermal barrier defects such as Netherton’ s syndrome is not recommended due to the potential for permanently increased systemic absorption of tacrolimus.