Hos frivillige forsøgspersoner med alvorlig nyreinsufficiens (kreatinin clearance < 30 ml/ min) øgedes den gennemsnitlige AUC med 21% og den gennemsnitlige Cmax faldt med 23%
In volunteers with severe renal impairment (creatinine clearance < 30 ml/ min) the mean AUC was increased by 21% and the mean Cmax decreased by 23%, compared to volunteers with no renal impairment.