Aktive substanser der kan reducere plasmakoncentration af dasatinib Når dasatinib administreredes efter 8 daglige aften- administrationer af 600 mg rifampicin, der er en potent CYP3A4- induktor, faldt AUC af dasatinib med 82%.
Active substances that may decrease dasatinib plasma concentrations When dasatinib was administered following 8 daily evening administrations of 600 mg rifampicin, a potent CYP3A4 inducer, the AUC of dasatinib was decreased by 82%.