Hos HIV- inficerede patienter, såvel som hos hæmodialyse- patienter og personer med nedsat immunforsvar, kan adækvate anti- HB antistoftitre muligvis ikke opnås efter det primære immuniseringsprogram, og sådanne patienter kan derfor behøve administration af yderligere doser af vaccinen.
In HIV infected patients, as also in haemodialysis patients and persons with an impaired immune system, adequate anti-HBs antibody titers may not be obtained after the primary immunisation course and such patients may therefore require administration of additional doses of vaccine.