Der er rapporteret om pure red cell- aplasi forårsaget af neutraliserende antistoffer mod erytropoietin i forbindelse med rekombinante erytropoietiske proteiner, herunder darbepoetin alfa.
Pure red cell aplasia caused by neutralising anti-erythropoietin antibodies has been reported in association with recombinant erythropoietic proteins, including darbepoetin alfa.