Samtidig administration af ranitidin (300 mg enkeltdosis) og fosam - prenavir (1400 mg enkeltdosis) nedsatte plasma AUC for amprenavir med 30% og Cmax med 51%.
Concurrent administration of ranitidine (300 mg single dose) with fosamprenavir (1400 mg single dose) decreased plasma amprenavir AUC by 30% and Cmax by 51%.