4. 2) Metabolismen af ramipril til ramiprilat var forsinket hos patienter med nedsat leverfunktion, grundet formindsket aktivitet af leveresteraser, og således blev plasmakoncentrationen af ramipril hos disse patienter forøget.
In patients with impaired liver function, the metabolism of ramipril to ramiprilat was delayed due to diminished activity of hepatic esterases, and plasma ramipril levels in these patients were increased.