Lovastatin og simvastatin, som er meget afhængige af CYP3A4- metabolismen, forventes at have markant øgede plasmakoncentrationer, når de gives samtidig med darunavir, co- administreret med 100 mg ritonavir.
Lovastatin and simvastatin, which are highly dependent on CYP3A4 metabolism are expected to have markedly increased plasma concentrations when co-administered with darunavir co-administered with 100 mg ritonavir.