I begge studier var samtidig brug af konstante doser af folinsyre, orale kortikosteroider (≤ 10 mg/ dag) og/ eller nonsteroide anti- inflammatoriske stoffer (NSAIDs) tilladt.
In both studies concurrent use of stable doses of folic acid, oral corticosteroids (≤ 10 mg/ day) and/ or non-steroidal anti-inflammatory drugs (NSAIDs) was permitted.