Som det sås i undersøgelser med losartan alene, forekom føtale og neonatale bivirkninger, herunder nyretoksicitet og fosterdød, når gravide rotter blev behandlet med losartan/ hydrochlorthiazidkombinationen sent i gestationen og/ eller diegivningen.
As observed in studies with losartan alone, adverse foetal and neonatal effects, including renal toxicity and foetal death, occurred when pregnant rate were treated with the losartan/ hydrochlorothiazide combination during late gestation and/ or lactation.