Resistensmekanismer De bakterielle resistensmekanismer, der påvirker doripenem, omfatter inaktivering af det aktive stof forårsaget af carbapenemhydroliserende enzymer, muterede eller erhvervede PBP' er, reduceret ydre membranpermeabilitet og aktivt effluks.
Mechanisms of resistance Bacterial resistance mechanisms that effect doripenem include active substance inactivation by carbapenem-hydrolyzing enzymes, mutant or acquired PBP’s, decreased outer membrane permeability and active efflux.