Ved gentagen indgift (10 dages behandling med 50 mg riluzole to gange dagligt) fordobles akkumulationen af uomdannet riluzole i plasma, og steady state nås på mindre end 5 dage.
With multiple dose administration (10 day-treatment at 50 mg riluzole bid), unchanged riluzole accumulates in plasma by about 2 fold and steady-state is reached in less than 5 days.