Fluoxetin mangler enhver signifikant affinitet for neurotransmitterreceptorer, inklusive den muskarine kolinerge receptor, α- adrenerge receptorer, eller histaminerge H1- receptorer og har ikke nogen direkte virkning på hjertet.
Fluoxetine lacks any significant affinity for neurotransmitter receptors, including the muscarinic cholinergic receptor, α adrenergic receptors, or histaminergic H1 receptors, and does not have direct effects on the heart.