Induktion Som moderat inducer af CYP2C9 og let inducer af CYP3A4 og glukuronidering kan aprepitant i op til 2 uger efter initiering af dosisregimet nedsætte plasmakoncentrationen af substrater, der elimineres af disse.
Induction As a moderate inducer of CYP2C9 and a mild inducer of CYP3A4 and glucuronidation, aprepitant can decrease plasma concentrations of substrates eliminated by these routes within two weeks following initiation of dosing regimen.