Yderligere dosisjustering bør normalt foretages med dosisintervaller på 25 mikrogram i timen, idet der dog bør tages højde for patientens behov for yderligere analgesi og smertestatus.
Additional dose adjustment should normally be performed in 25 micrograms/ hour increments, although the supplementary analgesic requirements and pain status of the patient should be taken into account.