Meget høje enkeltdoser af oseltamivirphosphat havde ingen effekt hos voksne rotter, men resulterede derimod i toxicitet, herunder dødsfald, hos (juvenile) 7 dage gamle rotteunger.
Whereas very high oral single doses of oseltamivir phosphate had no effect in adult rats, such doses resulted in toxicity in juvenile 7-day-old rat pups, including death.