Hos 35 patienter, der fik 600 mg efavirenz en gang dagligt, var den højeste steady- state- koncentration (Cmax) 12, 9 ± 3, 7 µM (29%) [middel ± standarddeviation (S. D.) (variationskoefficient (% CV))], steady- state Cmin var 5, 6 ± 3, 2 µM (57%) og AUC var 184 ± 73 µM· t (40%).
In 35 patients receiving efavirenz 600 mg once daily, steady-state peak concentration (Cmax) was 12.9 ± 3.7 µM (29%) [mean ± standard deviation (S. D.) (coefficient of variation (%CV))], steady-state Cmin was 5.6 ± 3.2 µM (57%), and AUC was 184 ± 73 µM• h (40%).