Lacosamid binder endvidere til 'collapsin response mediator protein- 2 (CRMP- 2)', et fosfoprotein, der primært udtrykkes i nervesystemet og er involveret i neuronal differentiering og kontrol af udvækst af aksoner.
Further, lacosamide binds to collapsin response mediator protein-2 (CRMP-2), a phosphoprotein which is mainly expressed in the nervous system and is involved in neuronal differentiation and control of axonal outgrowth.