Isotretinoin er desuden kontraindiceret til patienter • med nyreinsufficiens • med stærkt forhøjede blodlipidværdier • med hypervitaminose A
Isotretinoin is contraindicated in women of childbearing potential unless all of the conditions of the Pregnancy Prevention Programme are met (see section 4.4 “ Special warnings and special precautions for use”).