Det kan dog ikke udelukkes, at langtidsbrug af ORACEA kan føre til udvikling af resistente tarmbakterier såsom Enterobacteriaceae og Enterococci samt til opformering af resistensgener.
However, it can not be excluded that long-term use of Oracea can lead to emergence of resistant intestinal bacteria such as Enterobacteriaceae and enterococci, as well as to enrichment of resistance genes.