Startdosen er 8, 8 mikrogram tre gange ugentligt de første to uger, efterfulgt af 22 mikrogram tre gange ugentligt de efterfølgende to uger.
When first starting treatment with Rebif, the dose should be slowly increased to avoid side effects, starting with 8.8 micrograms three times a week for the first two weeks, followed by 22 micrograms three times a week for the next two weeks.