Ambrisentan bliver glukuronideret via adskillige UGT- isoenzymer (UGT1A9S, UGT2B7S og UGT1A3S), og derved dannes ambrisentan- glukuronid (13%).
Ambrisentan is glucuronidated via several UGT isoenzymes (UGT1A9S, UGT2B7S and UGT1A3S) to form ambrisentan glucuronide (13%).