Dosisjustering er kun nødvendig ved behandling af patienter med nedsat nyrefunktion, der får potente CYP3A4- hæmmere, såsom: • proteasehæmmere (undtagen tipranavir/ ritonavir) • ketokonazol, itraconazol, clarithromycin, telithromycin.
Renal impairment: dosage adjustment is only recommended in patients with renal impairment who are receiving potent CYP3A4 inhibitors such as: • protease inhibitors (except tipranavir/ ritonavir) • ketoconazole, itraconazole, clarithromycin, telithromycin.