Disse stigninger forsvandt ved fortsat behandling og var i de fleste tilfælde associeret med en reduktion i virusmængden på ≥ 2 log10 kopier/ ml, som gik forud for eller faldt sammen med ALAT- stigningen.
Among tenofovir disoproxil fumarate-treated patients, on-treatment ALT elevations had a median time to onset of 8 weeks, resolved with continued treatment, and, in a majority of cases, were associated with a ≥ 2 log10 copies/ ml reduction in viral load that preceded or coincided with the ALT elevation.