Når APTIVUS givet sammen med lavdosis ritonavir blev givet sammen med 20 ml aluminium - og magnesium- baseret flydende antacida, blev tipranavirs AUC12t, Cmax og Cmin reduceret med 25 - 29%.
When APTIVUS, co-administered with low dose ritonavir, was co-administered with 20 ml of aluminium- and magnesium-based liquid antacid, tipranavir AUC12h, Cmax and Cmin were reduced by 25-29%.