Hos patienter med moderat leverdysfunktion (Child- Pugh score 7- 9) bør dosis på 60 mg hver anden dag ikke overskrides uanset indikationen; administration af 30 mg én gang dagligt kan også overvejes.
In patients with moderate hepatic dysfunction (Child-Pugh score 7-9), regardless of indication, the dose of 60 mg every other day should not be exceeded; administration of 30 mg once daily can also be considered.