På tidspunktet for en forudspecificeret interimanalyse var det primære effektmål, tid til progression, opnået, og patienterne i M+P- gruppen blev tilbudt Vc+M+P- behandling.
At the time of a pre-specified interim analysis, the primary endpoint, time to progression, was met and patients in the M+P arm were offered Vc+M+P treatment.