Sitagliptin adskiller sig i kemisk struktur og farmakologisk virkning fra GLP- 1- analoger, insulin, sulfonylurinstoffer eller meglitinider, biguanider, peroxisom- proliferatoraktiverede receptorgammaagonister (PPARγ), alfaglucosidasehæmmere og amylinanaloger.
Sitagliptin differs in chemical structure and pharmacological action from GLP-1 analogues, insulin, sulphonylureas or meglitinides, biguanides, peroxisome proliferator-activated receptor gamma (PPARγ) agonists, alpha- glucosidase inhibitors, and amylin analogues.