Interaktioner forbundet med amlodipin Forsigtighed ved samtidig brug CYP3A4- hæmmere Et studie med ældre patienter har vist, at diltiazam hæmmer metabolismen af amlodipin, sandsynligvis via CYP3A4 (plasmakoncentration forhøjes med ca 50% og virkningen af amlodipin er øget).
Interactions linked to amlodipine Caution required with concomitant use CYP3A4 inhibitors A study in elderly patients has shown that diltiazem inhibits the metabolism of amlodipine, probably via CYP3A4 (plasma concentration increases by approximately 50% and the effect of amlodipine is increased).