Der sås retinal degeneration ved transmissionsmikroskopi ved en dosis svarende til 2, 8 gange den maksimale anbefalede dosis for mennesker på en mg/ m2- basis i et 3- måneders forsøg med albinorotter.
Retinal degeneration was observed by transmission microscopy at a dose equivalent to 2.8 times the maximum recommended human dose on a mg/ m² basis in a 3-month study in albino rats.