Det aktive stof i ORENCIA, abatacept, er et protein, der er udformet, så det hæmmer aktiviteten af "T- celler", de særlige celler i immunsystemet, der er medvirkende til inflammation og ledskader ved leddegigt.
The active substance in ORENCIA, abatacept, is a protein that has been designed to suppress the activity of ‘ T-cells’, specific cells in the immune system (the body’ s defence system) that are involved in causing inflammation and joint damage in rheumatoid arthritis.