Hos personer med mildt (kreatininclearance 50- 80 ml/ min.), moderat (kreatininclearance 30- 49 ml/ min.) og svært (kreatininclearance 15- 29 ml/ min.) nedsat nyrefunktion sås der en stigning i plasmakoncentrationerne af rivaroxaban (AUC) på henholdsvis 1, 4, 1, 5 og 1, 6 gange.
In individuals with mild (creatinine clearance 50 - 80 ml/ min), moderate (creatinine clearance 30 - 49 ml/ min) and severe (creatinine clearance 15 - 29 ml/ min) renal impairment, rivaroxaban plasma concentrations (AUC) were increased 1.4, 1.5 and 1.6 fold respectively.