Det er muligt, at der på grund af de alsidige behandlingsformer til disse patienter (diæt, medicin og understøttende behandling) er en overvurderet kliniske effekt af betainbehandlingen.
It is likely that due to the multiple nature of therapy (dietary, pharmaceutical, supportive) in these patients, there may be an element of overestimation in the clinical effects of betaine treatment.