Langvarig systemisk eksponering for intens immunosuppression hos transplanterede patienter efter systemisk administration af calcineurin- inhibitorer er blevet associeret med en øget risiko for udvikling af lymfomer og hudmaligniteter.
Prolonged systemic exposure to intense immunosuppression in transplant patients following systemic administration of calcineurin inhibitors has been associated with an increased risk of developing lymphomas and skin malignancies.