Hos forsøgspersoner med svært nedsat nyrefunktion (kreatininclearance 10– 30 ml/ min) skønnedes det, at ranolazineksponeringen steg 1, 3– 1, 8 gange.
In subjects with severe renal impairment (creatinine clearance 10– 30 ml/ min), a 1.3- to 1.8-fold increase in ranolazine exposure was estimated.