Selvom graden af nyreinsufficiens kun har lille indflydelse på histamins PK- disposition, bør der udvises forsigtighed ved anvendelse af histamin til patienter med svær nyreinsufficiens.
Although the degree of renal impairment has little effect on the PK disposition of histamine, caution should be used in the administration of histamine to patients with severe renal impairment.