Efter indgivelse af en enkelt dosis panitumumab som 1 times infusion øgedes area under the concentration- curve (AUC) mere end på en dosisproportionel måde, og clearancen (CL) af panitumumab faldt fra 30, 6 til 4, 6 ml/ dag/ kg, da dosis steg fra 0, 75 til 9 mg/ kg.
Following a single-dose administration of panitumumab as a 1-hour infusion, the area under the concentration-time curve (AUC) increased in a greater than dose-proportional manner and clearance (CL) of panitumumab decreased from 30.6 to 4.6 ml/ day/ kg as the dose increased from 0.75 to 9 mg/ kg.