Systemisk absorption af hydrocortisonaceponat er negligerbar, derfor er det usandsynligt, at der forekommer teratogen, foetotoxisk, maternotoxisk effekt ved den anbefalede dosering hos hunde.
Systemic absorption of hydrocortisone aceponate being negligible, it is unlikely for teratogenic, foetotoxic, maternotoxic effects to happen at the recommended dosage in dogs.