Neurotoksicitet, hovedsagelig perifer neuropati, sunes af forekomme oftere og alvorligere med en 175 mg/ m2 3 timers infusion (85% neurotoksicitet, 15% alvorlig) end med en 135 mg/ m2 24 timers infusion (25% perifer neuropati, 3% alvorlig), når paclitaxel blev kombineret med cisplatin.
Neurotoxicity, mainly peripheral neuropathy, appeared to be more frequent and severe with a 175 mg/ m2 3 hour infusion (85% neurotoxicity, 15% severe) than with a 135 mg/ m2 24 hour infusion (25% peripheral neuropathy, 3% severe) when paclitaxel was combined with cisplatin.