Behandlingen skal derfor indledes med forsigtighed hos disse patienter, og der skal udvises særlig forsigtighed hvis dosis øges til 10 mg.
There is limited experience with Volibris in individuals with severe renal impairment (creatinine clearance < 30 ml/ min); initiate therapy cautiously in this subgroup and take particular care if the dose is increased to 10 mg Volibris.