Efter en enkeltdosis rotigotin var der en tydelig binding til væv, som indeholder melanin (dvs. øjne), hos den pigmenterede rotte og abe, men den fortog sig langsomt i den 14- dages observationsperiode.
After a single dose of rotigotine, binding to melanin-containing tissues (i. e., eyes) in the pigmented rat and monkey was evident, but was slowly cleared over the 14-day observation period.