I løbet af de 4 års osteoporosebehandlingsforsøg (med 7705 patienter), reducerede EVISTA - behandling risikoen for brystcancer i forhold til placebo med 62% (relativ risiko 0, 38, konfidens - interval 0, 21- 0, 69), risikoen for invasiv brystcancer med 71% (relativ risiko 0, 29, konfidensinterval 0, 13- 0, 58) samt risikoen for invasiv østrogenreceptor- positiv brystcancer med 79% (relativ risiko 0, 21, konfidensinterval 0, 07- 0, 50).
Over the 4 years of the osteoporosis treatment trial (involving 7705 patients), EVISTA treatment compared to placebo reduced the risk of total breast cancer by 62% (RR 0.38; CI 0.21, 0.69), the risk of invasive breast cancer by 71% (RR 0.29, CI 0.13, 0.58) and the risk of invasive oestrogen receptor (ER) positive breast cancer by 79% (RR 0.21, CI 0.07, 0.50).