Anvendelse af etoricoxib 120 mg sammen med hormonsubstitutionsbehandling bestående af konjugerede østrogener (0, 625 mg PremarinTM), i 28 dage, øgede den gennemsnitlige steady- state AUC0- 24t af ukonjugeret estron (41%), equilin (76%) og 17- ß- østradiol (22%).
Administration of etoricoxib 120 mg with hormone replacement therapy consisting of conjugated estrogens (0.625 mg PREMARINTM) for 28 days, increased the mean steady state AUC0-24hr of unconjugated estrone (41%), equilin (76%), and 17-β -estradiol (22%).