Farmakokinetikken af topotecan ved oral administration er vurderet hos cancerpatienter efter administration af 1, 2 - 3, 1 mg/ m2/ dag og 4 mg/ m2/ dag dagligt i 5 dage.
The pharmacokinetics of topotecan after oral administration have been evaluated in cancer patients following doses of 1.2 to 3.1 mg/ m2/ day and 4 mg/ m2/ day administered daily for 5 days.