Ni ud af de 74 bosentan- behandlede patienter, der havde forhøjede leveraminotransferaser (> 3 × ULN), havde også symptomer som mavesmerter, kvalme/ opkastning og feber.
Nine of the 74 bosentan-treated patients who had elevated liver aminotransferases (> 3 × ULN) also had symptoms such as abdominal pain, nausea/vomiting, and fever.