Enkelte doser på 1500 mg/ kg (9000 mg/ m2) og 720 mg/ kg (14. 400 mg/ m2) tolereredes uden væsentlig toksicitet hos henholdsvis rotter og hunde.
Single doses of 1500 mg/ kg (9000 mg/ m2) and 720 mg/ kg (14,400 mg/ m2) were tolerated without significant toxicity in rats and dogs, respectively.