Patienter, der aldrig har røget havde en større effekt af erlotinib (overlevelse HR = 0, 42; konfidensinterval 0, 28- 0, 64) sammenlignet med rygere eller ex- rygere (HR = 0, 87; konfidensinterval 0, 71- 1, 05).
Patients who never smoked had a much greater benefit from erlotinib (survival HR = 0.42, CI 0.28-0.64) compared with current or ex-smokers (HR = 0.87, CI 0.71-1.05).