Abacavir og lamivudin bliver ikke signifikant metaboliseret af cytokrom P450 enzymer (såsom CYP 3A4, CYP 2C9, CYP 2D6) og de hverken hæmmer eller inducerer dette enzymsystem.
Abacavir and lamivudine are not significantly metabolised by cytochrome P450 enzymes (such as CYP 3A4, CYP 2C9 or CYP 2D6) nor do they inhibit or induce this enzyme system.