Klinisk signifikante interaktioner forventedes ikke, da NRTIer metaboliseres via en anden vej end efavirenz, og det ville være usandsynligt, at de ville konkurrere om de samme metaboliske enzymer og eliminationsveje.
Clinically significant interactions would not be expected since the NRTIs are metabolised via a different route than efavirenz and would be unlikely to compete for the same metabolic enzymes and elimination pathways.