Behandling med nitisinon leder til normaliseret porfyrinmetabolisme med normal erythrocyt PBG - syntaseaktivitet og urin 5- ALA, nedsat udskillelse af succinylacetone i urinen, øget plasmakoncentration af tyrosin og øget udskillelse af fenolsyrer i urinen.
Nitisinone treatment leads to normalised porphyrin metabolism with normal erythrocyte PBG- synthase activity and urine 5-ALA, decreased urinary excretion of succinylacetone, increased plasma tyrosine concentration and increased urinary excretion of phenolic acids.