Der er observeret en øget systemisk eksponering af darunavir ved samtidig brug af PREZISTA, co- administreret med 100 mg ritonavir sammen med rifabutin (150 mg x 1 hver anden dag).
An increase of systemic exposure to darunavir was observed when PREZISTA co-administered with 100 mg ritonavir was co-administered with rifabutin [150 mg q.o.d.