52 med 300 mg irbesartan alene, medførte yderligere placebo- korrigeret diastolisk blodtryksreduktion ved laveste måling (24 timer efter dosis) på 6, 1 mmHg.
The addition of 12.5 mg hydrochlorothiazide to 300 mg irbesartan once daily in patients not adequately controlled on 300 mg irbesartan alone resulted in further placebo-corrected diastolic blood pressure reductions at trough (24 hours post-dosing) of 6.1 mm Hg.