2, 7 gange højere hos frivillige, med moderat nyreinsufficiens (CrCL mellem 30- 50 ml/ min) end hos dem uden nyreinsufficiens.
The exposure (AUC) of dabigatran after the oral administration of Pradaxa is approximately 2.7 fold higher in volunteers with moderate renal insufficiency (CrCL between 30 – 50 ml/ min) than in those without renal insufficiency.