Det elimineres hovedsageligt gennem tyndtarmen, hvilket udgør en fordel i forhold til resten af tetracyclinerne, fordi det ikke akkumuleres i organismen, når nyrefunktionen er nedsat, eftersom det ikke er dets hovedeliminationsvej.
It is mainly eliminated through the small intestine that supposes an advantage in relation to the rest of tetracyclines provided that it is not accumulated in the organism when renal function is diminished since it is not its mainly route of elimination.