Selvom brækreflexen kan forsvinde hos dybt komatøse patienter, kan selv bevidstløse patienter modarbejde intubation, og hurtig sekvens induktion (uden brug af sedativa) bør overvejes.
Although gag reflex may be absent in deeply comatose patients, even unconscious patients may become combative to intubation, and rapid sequence induction (without the use of sedative) should be considered.