Kelation af jern især gennem en “ åben ring ” - metabolit reducerer oxidativt stress forårsaget af jernafhængige frie radikaler i forbindelse med antracyklin- induceret kardiotoksicitet.
Prevention of anthracycline cardiotoxicity: chelation of iron especially through its ring-opened metabolite reduces the iron-dependant free radical oxidative stress associated with anthracycline- induced cardiotoxicity.