I fire af undersøgelserne blev virkningen af Humira sammenlignet med placebo (virkningsløs behandling), enten alene eller som tillægsbehandling til andre antiinflammatoriske lægemidler, herunder methotrexat, hos over 2000 patienter.
In four of these studies, the effectiveness of Humira, alone or as an as add-on to other anti-inflammatory medicines including methotrexate, was compared with that of placebo (a dummy treatment) in over 2,000 patients.