En 12- ugers undersøgelse hos voksne viste signifikant reduktion i anstrengelsesudløst bronkokonstriktion (maksimalt fald i FEV1 22, 33% for montelukast versus 32, 40% for placebo; tid til restitution til inden for 5% af baseline FEV1 44, 22 min versus 60, 64 min).
Significant reduction of exercise-induced bronchoconstriction (EIB) was demonstrated in a 12-week study in adults (maximal fall in FEV1 22.33% for montelukast vs 32.40% for placebo; time to recovery to within 5% of baseline FEV1 44.22 min vs 60.64 min).