Nedsat nyrefunktion Forhøjede plasmakoncentrationer af duloxetin forekommer hos patienter med svært nedsat nyre - funktion i hæmodialyse (kreatinin- clearance < 30 ml/ min.).
Renal impairment Increased plasma concentrations of duloxetine occur in patients with severe renal impairment on haemodialysis (creatinine clearance < 30 ml/ min).