I humane in vitro mikrosomale og hepatocyt - studier, resulterer hydrolyse af amidgruppen i den C- terminale aminosyre, phenylalanin, i en deamineret metabolit, og dannelsen af denne metabolit er ikke NADPH- afhængig.
In in vitro human microsomal and hepatocyte studies, hydrolysis of the amide group of the C-terminus amino acid, phenylalanine results in a deamidated metabolite and the formation of this metabolite is not NADPH dependent.