In vitro- test med humane mikrosomer viste, at samtidig behandling med stoffer, som metaboliseres ved CYP450- isoformer, kan resultere i højere eller lavere plasmaniveauer af enten masitinib eller disse stoffer.
In vitro tests with human microsomes demonstrate that concomitant treatment with substances which are metabolised by CYP450 isoforms may result in higher or lower plasma levels of either masitinib or those substances.