Hos raske forsøgspersoner ændrer peroral prednison (20 mg, 3 gange dagligt i 5 dage) ikke alendronats perorale biotilgængelighed i signifikant grad (gennemsnitlig stigning fra 20- 44%).
In healthy subjects, oral prednisone (20 mg three times daily for five days) did not produce a clinically meaningful change in oral bioavailability of alendronate (a mean increase ranging from 20% to 44%).