I en toårig carcinogenicitetsundersøgelse af rotter observeredes en øget forekomst af ovarietumorer af granulosa - / thecacelle oprindelse hos højdosis hunner (279 mg/ kg/ dag).
In a 2-year carcinogenicity study in rats, an increase in ovarian tumors of granulosa/ theca cell origin was observed in high-dose females (279 mg/ kg/ day).