Dyreforsøg angående fordelingen i væv hat vist at daptomycin hovedsageligt fordeles i meget vaskulariseret væv og i mindre grad passerer blod- hjernebarrieren og placentabarrieren efter enkelt - og multiple doser.
Tissue distribution studies in animals have shown that daptomycin preferentially distributes into highly vascularised tissues and to a lesser degree penetrates the blood-brain barrier and the placental barrier following single and multiple doses.