Irbesartan Hydrochlorothiazide Winthrop må heller ikke gives til patienter, som har svære lever -, nyre - eller galdeproblemer, for lavt indhold af kalium i blodet eller for højt indhold af kalcium i blodet.
Irbesartan Hydrochlorothiazide Winthrop should also not be used in patients who have severe liver, kidney or bile problems, blood potassium levels that are too low or blood calcium levels that are too high.