Disse farmakologisk betingede bivirkninger, som er kendt fra prækliniske forsøg med både ACE- hæmmere og angiotensin II- receptorantagonister, kunne forhindres/ afhjælpes ved peroral salttilførsel.
These pharmacologically- mediated undesirable effects, known from preclinical studies with both angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists, were prevented by oral saline supplementation.