I tilfælde af klinisk forværring (f. eks. mindst 10% reduktion i 6- minutters gangtest i sammenligning med målinger inden behandlingens start) på trods af Tracleer behandling i mindst 8 uger (måldosis i mindst 4 uger), bør alternativ behandling overvejes.
In the case of clinical deterioration (e. g., decrease in 6-minute walk test distance by at least 10% compared with pre-treatment measurement) despite Tracleer treatment for at least 8 weeks (target dose for at least 4 weeks), alternative therapies should be considered.