Efter multipel dosering med 750 mg hver 8. time i 28 dage (steady- state), var gennemsnittet for peak- plasmakoncentrationer (Cmax) 3- 4 µg/ ml og plasmakoncentrationerne inden næste dosis (trough) var 1- 3 µg/ ml.
After multiple dosing with 750 mg every 8 hours for 28 days (steady-state), peak plasma concentrations (Cmax) averaged 3-4 µg/ml and plasma concentrations prior to the next dose (trough) were 1-3 µg/ml.