Clearance af total IGF- 1 er omvendt proportional med serum IGFBP- 3- niveauer, og total systemisk IGF- 1- clearance (CL/ F) anslås til at være 0, 04 l/ t/ kg ved 3 mg/ l IGFBP- 3 hos 12 patienter.
Clearance of total IGF-1 is inversely proportional to serum IGFBP-3 levels and total IGF-1 systemic clearance (CL/ F) is estimated to be 0.04 l/ hr/ kg at 3 mg/ l IGFBP-3 in 12 subjects.