Sygdomme i hud og subkutane væv Lejlighedsvis ses der akut eksacerbation af acne i den initiale periode, men den forsvinder under fortsat behandling, normalt inden for 7- 10 dage, og kræver sædvanligvis ingen dosisjustering.
Skin and subcutaneous tissues disorders Acute exacerbation of acne is occasionally seen during the initial period but this subsides with continued treatment, usually within 7 - 10 days, and usually does not require dose adjustment.