Sikkerhedsfarmakologiske data i cynomolgus aber afslørede reduktion i blodtryk efterfulgt af forandringer af ECG, men disse fremkom ved eksponeringer der var langt højere end den kliniske eksponering.
Safety pharmacology data in cynomolgus monkeys revealed reduction of blood pressure followed by changes of ECG, but these occurred at exposures that were considerably higher than the clinical exposure.