Overdosering med oxybutynin er blevet sat i forbindelse med antikolinergiske effekter, herunder CNS- excitation, hedeture, feber, dehydrering, hjertearytmier, opkastning og urinretention.
Overdosage with oxybutynin has been associated with anticholinergic effects including CNS excitation, flushing, fever, dehydration, cardiac arrhythmia, vomiting, and urinary retention.