85 Abl- positive cellelinier såvel som i friske leukæmiceller fra Philadelphia- kromosompositiv (Ph+) CML og hos patienter med akut lymfoblastisk leukæmi (ALL).
The compound selectively inhibits proliferation and induces apoptosis in Bcr-Abl positive cell lines as well as fresh leukaemic cells from Philadelphia chromosome positive CML and acute lymphoblastic leukaemia (ALL) patients.