Tipranavir givet sammen med lavdosis ritonavir (500 mg/ 200 mg to gange daglig) resulterede i en 29 gange øgning i den geometiske mean morgen steadystate ” trough ” plasmakoncentration sammenlignet med tipranavir 500 mg to gange daglig uden ritonavir
Tipranavir co-administered with low dose ritonavir (500 mg/ 200 mg twice daily) was associated with a 29-fold increase in the geometric mean morning steady-state trough plasma concentrations compared to tipranavir 500 mg twice daily without ritonavir.