Thiazider kan reducere nyreudskillelsen af cytotoksiske stoffer (fx cyklofosfamid, methotrexat) og forstærke deres myelosuppresive effekt.
Thiazides may reduce the renal excretion of cytotoxic medicinal products (e. g. cyclophosphamide, methotrexate) and potentiate their myelosuppressive effects.