Hvis kreatininclearance er < 30 ml/ minut/ 1, 73 m2 eller kreatininkoncentrationen > 175 µmol/ l, er maksimal daglig intravenøs dosis 400 mg.
If creatinine clearance is ≤ 30 ml/ minute/ 1.73 m2 or the serum creatinine concentration is ≥ 175 µmol/ l, the maximum daily intravenous dose is 400 mg.