Patienter med monofokal eller multifokal udløsning af sygdommen blev inkluderet (dvs. patienter med klinisk evidens for hhv. en enkelt eller mindst to læsioner i centralnervesystemet).
Patients with monofocal or multifocal onset of the disease were included (i. e. patients with clinical evidence for a single or at least two lesions, respectively, of the central nervous system).