Selvom sammenlignende resultater mangler, indikerer begrænsede data hos patienter, der initialt responderede på 5 mg/ kg, men som mistede respons, at nogle patienter kan genvinde respons med dosisoptrapning (se pkt.
Although comparative data are lacking, limited data in patients who initially responded to 5 mg/ kg but who lost response indicate that some patients may regain response with dose escalation (see section 5.1).