Hos ikke- rygere versus rygere (mænd og kvinder) var den gennemsnitlige eliminations halveringstid forlænget (38, 6 versus 30, 4 timer) og clearance reduceret (18, 6 versus 27, 7 l/ time).
54 prolonged (38.6 versus 30.4 hr) and the clearance was reduced (18.6 versus 27.7 l/ hr).