21 behandlede patienter og 1 vancomycin- behandlet patient, som udviklede tiltagende MICer på eller efter behandling (se ” Resistensmekanisme ” ovenfor).
Among these failures six patients treated with Cubicin and one patient treated with vancomycin were infected with Staphylococcus aureus that developed increasing MICs of daptomycin on or following therapy (see “ Mechanisms of resistance” above).