Creatininclearance påvirkede den systemiske eksponering af 5 ’ - DFUR (35% stigning i AUC, når creatininclearance aftog med 50%) og FBAL (114% stigning i AUC, når creatininclearance aftog med 50%).
Creatinine clearance was found to influence the systemic exposure to 5’ -DFUR (35% increase in AUC when creatinine clearance decreases by 50%) and to FBAL (114% increase in AUC when creatinine clearance decreases by 50%).