Baseret på den offentliggjorte litteratur indikerer in vitro undersøgelser af binding til humane serumproteiner, som anvender paclitaxel ved koncentrationer, der strækker sig fra 0, 03 til 1, 2 µM, at omkring 87%
Based on the published literature, in vitro studies of binding to human serum proteins, using paclitaxel at concentrations ranging from 0.03 to 1.2 µM, indicate that about 87% of paclitaxel is bound; the presence of ranitidine, dexamethasone, or diphenhydramine did not affect protein binding of paclitaxel.