13 CYP3A4- induktorer Efter induktion af CYP3A4 ved samtidig administration af rifampicin 600 mg 1 gang dagligt faldt Cmax og AUC for fesoterodins aktive metabolit med henholdsvis cirka 70% og 75% efter oral administration af 8 mg fesoterodin.
CYP3A4 Inducers Following induction of CYP3A4 by coadministration of rifampicin 600 mg once a day, Cmax and AUC of the active metabolite of fesoterodine decreased by approximately 70% and 75%, respectively, after oral administration of fesoterodine 8 mg.