Resistens over for efavirenz kan selekteres in vitro og resulterede i enkle eller multiple aminosyresubstitutioner i HIV- 1 RT, herunder L100I, V108I, V179D og Y181C.
25 Resistance: resistance to efavirenz can be selected in vitro and resulted in single or multiple amino acid substitutions in HIV-1 RT, including L100I, V108I, V179D, and Y181C.