Ifølge Clinical og Laboratory Standard Institute (CLSI) forordningen anses andre organismer end streptococci med MIC værdier ≤ 4 µg/ ml for følsomme ved 8 µg/ ml gennemsnitligt og med MIC værdier ≥ 16 µg/ ml for resistente mod doxycyclin.
According to the Clinical and Laboratory Standard (CLSI) regulation, organisms other than streptococci with MIC values ≤ 4 µg/ ml are considered sensitive, at 8 µg/ ml intermediate and with MIC values ≥ 16 resistant to doxycycline.