To mellemprodukter, dannet under nedbrydningen af caspofungin ved ringåbning, danner kovalente adduktorer til plasmaproteiner, resulterende i irreversibel binding til plasmaproteiner i mindre grad.
Two intermediate products, formed during the degradation of caspofungin to this open ring compound, form covalent adducts to plasma proteins resulting in a low-level, irreversible binding to plasma proteins.