Samtidig administration af Tarceva med 300 mg ranitidin, en H2- receptor- antagonist, nedsatte erlotinibeksponeringen [AUC] og maksimumkoncentrationerne [Cmax] med henholdsvis 33% og 54%.
Concomitant administration of Tarceva with 300 mg ranitidine, an H2-receptor antagonist, decreased erlotinib exposure [AUC] and maximum concentrations [Cmax] by 33% and 54%, respectively.