Dette fører til en afslapning af musklerne i svulmelegemet (corpora cavernosa), hvorved blodstrømningen til corpora øges, hvilket medfører erektion.
During normal sexual stimulation, cGMP is produced in the penis, where it causes the muscle in the spongy tissue of the penis (the corpora cavernosa) to relax, allowing the inflow of blood in the corpora that produces the erection.