Metabolisme In vitro- forsøg har vist, at der kun er begrænset eller ingen mikrosomal- medieret levermetabolisme af daptomycin hos mennesker, og at CYP450- systemet kun er minimalt involveret i daptomycins metabolisme.
Metabolism In vitro studies have demonstrated that there is no or limited liver microsomal mediated metabolism of daptomycin in humans and that CYP450 involvement in daptomycin metabolism is minimal.