Der er indkommet case- rapporter om maligne lidelser i forbindelse med brug af Protopic (bestående i hudkræft, kutant T- celle lymfom (CTCL), non- Hodgkin lymfom (NHL) og systemiske maligne sygdomme) under den kliniske udvikling og efter markedsføring.
Case reports of malignancies (including skin cancer, cutaneous T-Cell lymphoma (CTCL), Non- Hodking lymphoma (NHL) and systemic malignancies) have been received during the clinical development and post-marketing experience in association with the use of Protopic.