Det anbefales, at behandlingen påbegyndes efter transfusion af omkring 20 enheder (cirka 100 ml/ kg) pakkede røde blodceller, eller når klinisk monitorering afdækker tegn på, at kronisk jernophobning er tilstede (f. eks. serum- ferritin > 1. 000 µg/ l).
It is recommended that treatment be started after the transfusion of approximately 20 units (about 100 ml/ kg) of packed red blood cells or when there is evidence from clinical monitoring that chronic iron overload is present (e. g. serum ferritin > 1,000 µg/ l).