Nedsat leverfunktion Ved nedsat leverfunktion i forbindelse med levercirrose sås nedsat lisinopril absorption (omkring 30% bestemt ud fra urin udskillelsen) men en øget eksponering (omkring 50%) sammenlignet med raske individer på grund af nedsat clearance.
Hepatic impairment Impairment of hepatic function in cirrhotic patients resulted in a decrease in lisinopril absorption (about 30% as determined by urinary recovery) but an increase in exposure (approximately 50%) compared to healthy subjects due to decreased clearance.