Patienter som har oplevet forsinket tidlig methotrexat elimination udvikler sandsynligvis reversibel nyresvigt og alle toksiciteter associeret med methotrexat (se venligst produktresumé for methotrexat).
Patients who experience delayed early methotrexate elimination are likely to develop reversible renal failure and all toxicities associated with methotrexate (please refer to the SPC for methotrexate).