53 gange AUC hos mennesker) eller kaniner op til en dosis på 3 mg/ kg (under niveauet for systemisk eksponering hos mennesker).
Lasofoxifene was not teratogenic in rats up to a dose of 10mg/ kg (approximately 53 times the AUC in humans) or rabbits up to a dose of 3 mg/ kg (below the level of systemic exposure in humans).