Ranexa 1. 000 mg to gange dagligt fik plasmakoncentrationen af simvastatinlakton, simvastatinsyre og HMG - CoA- reduktase- hæmmerens aktivitet til at stige 1, 4- 1, 6 gange.
Ranexa 1000 mg twice daily increased plasma concentrations of simvastatin lactone, simvastatin acid, and the HMG-CoA reductase inhibitor activity by 1.4- to 1.6-fold.