Hos mennesker metaboliseres nicotinamid desuden overvejende til N - methylnicotinamid (MNA) og til N- methyl- 2- pyridon- 5- carboxamid (2PY).
In humans, nicotinamide is further predominantly metabolised to N-methylnicotinamide (MNA) and to N-methyl-2-pyridone-5-carboxamide (2PY).