Samtidig behandling med APTIVUS givet sammen med lavdosis ritonavir og amprenavir/ ritonavir, lopinavir/ ritonavir eller saquinavir/ ritonavir anbefales derfor ikke, idet den kliniske relevans ved reduktionen i niveauerne ikke er fastlagt.
Therefore the concomitant administration of APTIVUS, co-administered with low dose ritonavir, with amprenavir/ ritonavir, lopinavir/ ritonavir or saquinavir/ ritonavir, is not recommended, as the clinical relevance of the reduction in their levels has not been established.