Hos patienter, der behandles profylaktisk med protein C, kan højere forekomst af lave niveauer være berettiget i situationer med forøget risiko for trombose (som infektion, traume eller kirurgiske indgreb).
In patients receiving prophylactic administration of protein C, higher trough levels may be warranted in situations of an increased risk of thrombosis (such as infection, trauma, or surgical intervention).