Andetvalgsbehandlingen med firedobbelt behandling med en protonpumpe- hæmmer kombineret med vismutsubcitrat (subsalicylat) og metronidazol, og tertacyclin i mindst 7 dage er blevet anbefalet.
Second-line therapy with quadruple therapy using proton pump inhibitor combined with bismuth subcitrate (subsalicylate) and metronidazole, and tertacycline for a minimum of 7 days has been recommended.