For det andet hæmmer pravastatin produktionen af low- density lipoprotein (LDL) ved at hæmme den hepatiske syntese af very low- density lipoprotein (VLDL) - kolesterol, der er precursor til LDL - kolesterol.
Secondly, pravastatin inhibits the low-density lipoproteins (LDL) production by inhibiting the hepatic synthesis of very low-density lipoproteins (VLDL) cholesterol, the LDL-cholesterol precursor.