Startende hurtigst muligt og inden for 24 timer efter behandling skal dosen gradvist reduceres til 5 ppm, forudsat at den arterielle iltmætning er tilstrækkelig ved denne lavere dosis.
Starting as soon as possible and within 4-24 hours of therapy, the dose should be weaned to 5 ppm provided that arterial oxygenation is adequate at this lower dose.