Selvom der ikke sås bivirkninger i reproduktionsundersøgelser, når hundyr blev udsat for 3, 5- 4 gange den terapeutiske eksponering til mennesker ved 40 mg, vides det ikke, om ændringer i neurokinin - regulationen kan påvirke selve forplantningen.
Although no adverse effects were noted in reproduction studies when female animals were exposed 3.5- to 4-fold above the therapeutic exposure in humans at 40 mg, the potential effects on reproduction of alterations in neurokinin regulation are unknown.