Prækliniske evalueringer, der støtter administrationen af hydrochlorthiazid til mennesker, omfattede in vitro - genotoksicitetsanalyser og reproduktionstoksicitets - og carcinogenicitetsstudier af gnavere.
Preclinical evaluations to support the administration of hydrochlorothiazide in humans included in vitro genotoxicity assays and reproductive toxicity and carcinogenicity studies in rodents.