Duloxetins farmakokinetik viser stor variation mellem patienter (generelt 50- 60%), delvist på grund af køn, alder, ryger ikke - ryger status og CYP2D6 metaboliseringsstatus.
The pharmacokinetics of duloxetine demonstrate large intersubject variability (generally 50-60%), partly due to gender, age, smoking status and CYP2D6 metaboliser status.