Stavudin hæmmer ikke major cytokrom P450 isoformer CYP1A2, CYP2C9, CYP2C19, CYP2D6 og CYP3A4; det er derfor usandsynligt at klinisk signifikante lægemiddelinteraktioner vil optræde med stoffer, der metaboliseres via disse pathways.
Stavudine does not inhibit the major cytochrome P450 isoforms CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4; therefore, it is unlikely that clinically significant drug interactions will occur with drugs metabolised through these pathways.