In vitro - undersøgelser har ligeledes vist, at lægemidlet ikke hæmmer CYP2D6 og hverken er et substrat eller en hæmmer af P- glycoprotein.
Desloratadine does not inhibit CYP3A4 in vivo, and in vitro studies have shown that the medicinal product does not inhibit CYP2D6 and is neither a substrate nor an inhibitor of P-glycoprotein.