Tenofovirdisoproxilfumarat var positivt i Ames testen (stamme TA 1535) i to ud af tre undersøgelser, en gang med S9 mix (stigning på 6, 2 til 6, 8 gange) en gang uden S9 mix.
Tenofovir disoproxil fumarate was positive in the Ames test (strain TA 1535) in two out of three studies, once in the presence of S9 mix (6.2- to 6.8-fold increase) and once without S9 mix.