Targretin må desuden ikke anvendes i følgende situationer:  gravide eller ammende kvinder  kvinder, som kan blive gravide  enhver person, som har haft pankreatitis (betændelse i bugspytkirtlen)  ukontrolleret hyperkolesterolæmi (forhøjet kolesteroltal)  ukontrolleret hypertriglyceridæmi (forhøjede triglycerider (fedt) i blodet)  hypervitaminosis A (høje koncentrationer af A- vitamin)  ukontrolleret thyroidealidelse  leversygdom  infektion i kroppen.
Targretin should also not be used in the following situations:  women who are pregnant or breast-feeding  women who could become pregnant  anyone who has had pancreatitis (inflammation of the pancreas)  uncontrolled hypercholesterolaemia (high blood cholesterol).  uncontrolled hypertriglyceridaemia (high blood triglycerides [fat]).  hypervitaminosis A (high levels of vitamin A)  uncontrolled thyroid disease.  liver disease  where there is a body infection.