Enkeltdoser cholestyramin eller colestipol binder hydrochlorthiaziden og reducerer absorptionen af denne fra mave- tarmkanalen med op til henholdsvis 85% og 43%.
Single doses of either cholestyramine or colestipol resins bind the hydrochlorothiazide and reduce its absorption from the gastrointestinal tract by up to 85 and 43 percent, respectively.