Efter gentagen dosering af ritonavir til raske frivillige forsøgspersoner (500 mg to gange daglig) og forsøgspersoner med mild til moderat nedsat leverfunktion (Child- Pugh klasse A og B, 400 mg to gange daglig) var eksponeringen af ritonavir efter normalisering af dosis ikke signifikant forskellig for de to grupper.
Patients with impaired liver function: after multiple dosing of ritonavir to healthy volunteers (500 mg twice daily) and subjects with mild to moderate hepatic impairment (Child Pugh Class A and B, 400 mg twice daily) exposure to ritonavir after dose normalisation was not significantly different between the two groups.