Den gennemsnitlige (% variationskoefficient) tenofovireksponering steg fra 2. 185 (12%) ng• t/ ml hos probander med normal nyrefunktion til 3. 064 (30%) ng• t/ ml, 6. 009 (42%) ng• t/ ml og 15. 985 (45%) ng• t/ ml hos patienter med henholdsvis let, moderat og svært nedsat nyrefunktion.
The mean (%CV) tenofovir drug exposure increased from 2,185 (12%) ng• h/ ml in patients with normal renal function, to 3,064 (30%) ng• h/ ml, 6,009 (42%) ng• h/ ml and 15,985 (45%) ng• h/ ml, in patients with mild, moderate and severe renal impairment, respectively.