Patienter med svært nedsat nyrefunktion (CLcr < 30 ml/ min) som fik 10 mg oral ibandronsyre dagligt i 21 dage, havde 2- 3 gange højere plasmakoncentrationer end personer med normal nyrefunktion og den totale ibandronsyre clearance var 44 ml/ min.
Subjects with severe renal failure (CLcr less than 30 ml/ min) receiving daily oral administration of 10 mg ibandronic acid for 21 days, had 2-3 fold higher plasma concentrations than subjects with normal renal function and total clearance of ibandronic acid was 44 ml/ min.