I et 26- ugers gentagen dosis toksicitetsstudie i rhesusaber med intramuskulær administration én gang ugentlig, og givet i kombination med en anden immunmodulerende substans, et anti- CD40 ligand monoklonalt antistof, blev der ikke påvist noget immunrespons over for interferon- beta- 1a, og der var ingen tegn på toksicitet.
In a 26-week repeated dose toxicity study in rhesus monkeys by intramuscular route once per week, administered in combination with another immunomodulating agent, an anti CD40 ligand monoclonal antibody, no immune response toward interferon beta-1a and no signs of toxicity were demonstrated.