Toksisk påvirkning af rotters udvikling (fosterdødelighed, nedsat fostervægt, forsinket knogledannelse og ændringer i de indre organer, herunder forsinket testis retention) fandtes hovedsaglig ved en maternelt toksisk dosis.
Developmental toxicity observed in rats (embryolethality, decreased foetal body weight and ossification delays and visceral changes, including delayed testicular descent) occurred mainly at a maternally toxic dosage.