I gentagne toksicitetsundersøgelser på rotter var symptomerne på levertoksicitet forhøjede niveauer af leverenzymer og degenerative forandringer af hepatocytter, som blev ledsaget af symptomer på kompenserende regenerering.
In repe ated dose toxicity studies in rat signs of hepatotoxicity consisted of increased liver enzymes and degenerative changes of hepatocytes which were accompanied by signs of compensatory regeneration.