Serumkoncentrationen, der var nødvendig for at opnå et fald på 50% i blodplader fra baseline hos voksne cynomolgusaber, var cirka 4 - til 20- gange højere end forventede maksimale kliniske serumkoncentrationer.
The serum concentration required to attain a 50% drop in platelets from baseline in adult cynomolgus monkeys was roughly 4 to 20-fold higher than anticipated maximum clinical serum concentrations.