Selvom ændringerne i clarithromycin- parametre ikke anses for klinisk relevante, bør reduktionen af AUC for 14- OH- metabolitten tages med i overvejelserne ved behandling af infektioner forårsaget af Haemophilus influenzae, idet 14- OH- metabolitten den mest aktive.
Whilst the changes in clarithromycin parameters are not considered clinically relevant, the reduction in the 14-OH metabolite AUC should be considered for the treatment of infections caused by Haemophilus influenzae in which the 14-OH metabolite is most active.