Overlevelse og tumorprogression er undersøgt i fem store kontrollerede forsøg med i alt 2833 patienter, hvoraf fire var dobbeltblinde placebokontrollerede forsøg og et var et åbent forsøg.
Survival and tumour progression have been examined in five large controlled studies involving a total of 2833 patients, of which four were double-blind placebo-controlled studies and one was an open- label study.