Hos patienter med reumatoid arthritis sås øjeblikkelig B- celle depletering i perifert blod efter to infusioner af 1000 mg MabThera med 14 dages interval.
In rheumatoid arthritis patients, immediate depletion of B cells in the peripheral blood was observed following two infusions of 1000 mg MabThera separated by a 14 day interval.