MPA er en potent, selektiv, ikke- kompetitiv og reversibel inhibitor af inosin- monophosfat- dehydrogenase og hæmmer derfor de novo vejen for en guanosin- nucleotid - syntese uden inkorporering i DNA.
Mycophenolate mofetil is the 2-morpholinoethyl ester of mycophenolic acid (MPA). MPA is a potent, selective, uncompetitive and reversible inhibitor of inosine monophosphate dehydrogenase, and therefore inhibits the de novo pathway of guanosine nucleotide synthesis without incorporation into DNA.