En populationsanalyse af kombinerede data fra patienter og raske frivillige forsøgspersoner påviste, at hældningskoefficienten for plasmakoncentration/ QTc- forholdet vurderedes at være 2, 4 millisekund pr.
A population-based analysis of combined data from patients and healthy volunteers demonstrated that the slope of the plasma concentration-QTc relationship was estimated to be 2.4 msec per 1000 ng/ ml, which is approximately equal to a 2- to 7-msec increase over the plasma concentration range for ranolazine 500 to 1000 mg twice daily.