Nogle få patienter, som har oplevet hypoglykæmiske reaktioner efter skift fra animalsk insulin, har rapporteret, at de tidlige advarselssymptomer på hypoglykæmi var mindre udtalte eller forskellige fra dem, som de havde oplevet med deres tidligere insulin.
17 A few patients who have experienced hypoglycaemic reactions after transfer from animal source insulin have reported that early warning symptoms of hypoglycaemia were less pronounced or different from those experienced with their previous insulin.