Selvom klinisk erfaring har vist, at epileptiske anfald sjældent optræder hos patienter i behandling med mirtazapin, ligesom for andre antidepressiva, bør behandling med Remeron startes med forsigtighed til patienter, der har epileptiske anfald i anamnesen.
Although clinical experience indicates that epileptic seizures are rare during mirtazapine treatment, as with other antidepressants, Remeron should be introduced cautiously in patients who have a history of seizures.