28 ud af de 39 voksne, i alderen 16 - 65 år (i gennemsnit 34 år), var recidiverede eller refraktære i mindst to tidligere induktionsregimer.
Twenty– eight of the 39 adults had relapsed or were refractory to at least two prior induction regimens and aged between 16 to 65 years of age (mean 34 years).