Lignende ændringer blev observeret for metformin (hæmoglobin 3- 4% og hæmatokrit 3, 6- 4, 1% relative reduktioner) og i mindre grad for sulfonylurinstof og insulin (hæmoglobin 1- 2% og hæmatokrit 1- 3, 2% relative reduktioner) hos patienter i kontrollerede sammenlignende undersøgelser med pioglitazon.
Similar changes were seen in metformin (haemoglobin 3 - 4% and haematocrit 3.6 – 4.1% relative reductions) and to a lesser extent sulphonylurea and insulin (haemoglobin 1 – 2% and haematocrit 1 – 3.2% relative reductions) treated patients in comparative controlled trials with pioglitazone.