Årsagen til denne forskel er, at de fem 2- årige studier inkluderede en 4 ugers diæt og placebo indkøringsperiode, hvor patienterne tabte i gennemsnit 2, 6 kg, inden behandlingen startede.
The reason for this difference is that the five 2-year studies included a 4-week diet and placebo lead-in period during which patients lost on average 2.6 kg prior to commencing treatment.