Virkningsmekanisme Rosuvastatin er en selektiv og kompetitiv inhibitor af HMG- CoA reduktase, det hastighedsbegrænsende enzym som omdanner 3- hydroxy- 3- methylglutaryl coenzym A til mevalonat, et forstadie til kolesterol.
Mechanism of action Rosuvastatin is a selective and competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme that converts 3-hydroxy-3-methylglutaryl coenzyme A to mevalonate, a precursor for cholesterol.