Forsigtighed bør udvises, og dosen skal muligvis reduceres ved samtidig administration af mirtazapin og stærke CYP3A4- inhibitorer, HIV- proteaseinhibitorer, azol- svampemidler, erytromycin, cimetidin eller nefazodon.
Caution should be exercised and the dose may have to be decreased when co- administering mirtazapine with potent CYP3A4 inhibitors, HIV protease inhibitors, azole antifungals, erythromycin, cimetidine or nefazodone.