Hyppig monitorering af bivirkninger og toksicitet i forbindelse med methadon, herunder QTc- forlængelse, anbefales ved samtidig administration af voriconazol, da methadonniveauer stiger efter samtidig administration af voriconazol.
Frequent monitoring for adverse events and toxicity related to methadone, including QTc prolongation, is recommended when coadministered with voriconazole since methadone levels increased following co-administration of voriconazole.