45 gange højere end den højeste tilsvarende dosis beregnet til indgift til psoriasispatienter og betød, at de højeste serumkoncentrationer hos aber var mere end 100 gange højere end dem, der blev observeret hos mennesker.
Dose levels in animal studies were up to approximately 45-fold higher than the highest equivalent dose intended to be administered to psoriasis patients and resulted in peak serum concentrations in monkeys that were more than 100-fold higher than observed in humans.