Tilstedeværelse af krydsresistens mod andre protease- hæmmere blev analyseret i 18 rebound- isolater, som havde vist udvikling af resistens mod lopinavir under 3 fase II - og et fase III - forsøg med Kaletra i protease - hæmmer- erfarne- patienter.
The presence of cross resistance to other protease inhibitors was analysed in 18 rebound isolates that had demonstrated evolution of resistance to lopinavir during 3 Phase II and one Phase III studies of Kaletra in protease inhibitor-experienced patients.