Det blev bekræftet gennem evalueringer af patienter, der formodes at have en større risiko for bivirkninger, hvis de behandles med andre lægemidler mod angina pectoris, f. eks. patienter med diabetes, klasse I - og II - hjertesvigt eller obstruktive luftvejslidelser, at disse lidelser ikke var forbundet med klinisk relevante stigninger i bivirkningsincidensen.
Evaluations in patients who may be considered at higher risk of adverse events when treated with other antianginal medicinal products, e. g. patients with diabetes, Class I and II heart failure, or obstructive airway disease, confirmed that these conditions were not associated with clinically meaningful increases in the incidence of adverse events.