Dette kunne forklares ved følgende iagttagelser: i) Mitochondriemembranen gennemtrænges lettere af cargluminsyre end af N- acetylglutamat ii) Cargluminsyre er mere resistent end N- acetylglutamat overfor hydrolyse med aminoacylase tilstede i cytosolen.
This could be explained by the following observations: i) The mitochondrial membrane is more readily permeable for carglumic acid than for N- acetylglutamate ii) Carglumic acid is more resistant than N-acetylglutamate to hydrolysis by aminoacylase present in the cytosol.