De maksimale serumkoncentrationer (Cmax) nås cirka 2, 5 timer efter peroral indtagelse (gennemsnitligt 0, 3 µg/ ml ved gentagen dosering af 4 mg daglig), og der er lineær relation mellem dosis og såvel Cmax som AUC (areal under tid/ koncentration kurven).
Maximum serum concentrations (Cmax) are reached approximately 2.5 hours after oral intake (mean 0.3 µg/ ml during multiple dosing of 4 mg daily) and there is a linear relationship between dose and both Cmax and AUC (area under the time/ concentration curve).