Nonsteroide antiinflammatoriske lægemidler (NSAID) inklusive aspirin ≥ 3 g/ dag Indgift af nonsteroide antiinflammatoriske lægemidler kan reducere ACE- hæmmeres antihypertensive effekt.
In patients with renal impairment dose adjustment should be based on creatinine clearance values but these are not identical in all Member States as well as the recommended dose.