I klinisk undersøgelse C/ I98- 580 blev 1. 530 naive patienter behandlet i et år med et af følgende kombinationsregimen: • Rebetol (800 mg/ dag) + peginterferon alfa- 2b (1, 5 mikrogram/ kg/ uge) (n = 511). • Rebetol (1. 000/ 1. 200 mg/ dag) + peginterferon alfa- 2b (1, 5 mikrogram/ kg/ uge i en måned efterfulgt af 0, 5 mikrogram/ kg/ uge i 11 måneder) (n = 514). • Rebetol (1. 000/ 1. 200 mg/ dag) + interferon alfa- 2b (3 MIE tre gange om ugen) (n = 505).
In clinical trial C/I98-580, 1,530 naïve patients were treated for one year with one of the following combination regimens: • Rebetol (800 mg/day) + peginterferon alfa-2b (1.5 micrograms/kg/week) (n = 511). • Rebetol (1,000/1,200 mg/day) + peginterferon alfa-2b (1.5 micrograms/kg/week for one month followed by 0.5 microgram/kg/week for 11 months) (n = 514). • Rebetol (1,000/1,200 mg/day) + interferon alfa-2b (3 MIU three times a week) (n = 505).