Embryo- føtal- toksicitet (post- implantationstab, forsinket/ progressiv knogledannelse, hepatiske multiple svagt farvede pletter) og et øget antal tilfælde af almindelige misdannelser samt ændringer i placenta blev set ved klinisk relevante plasmakoncentrationer.
Embryo-foetal toxicity (post-implantation loss, retarded/ progressed ossification, hepatic multiple light coloured spots) and an increased incidence of common malformations as well as placental changes were observed at clinically relevant plasma concentrations.