Den selektive antagonisme mod angiotensin- II (AT1) receptorerne resulterer i enforhøjelse af plasma- renin - og angiotensin- II - niveauerne og i nedsat aldosteron i plasma.
The selective antagonism of the angiotensin-II (AT1) receptors results in increases in plasma renin levels and angiotensin-II levels, and a decrease in plasma aldosterone concentration.