Derfor forventes ingen særlig interaktion, hvilket bekræftes af in vivo- studier, hvor der ikke blev fundet inhibition af metaboliseringen af følgende aktive substanser: tricykliske antidepressiva (hovedsageligt CYP2D6), warfarin (CYP2C9), theophyllin (CYP1A2) eller diazepam (CYP3A4 og 2C19).
Thus no particular interaction is expected as verified through in vivo studies where no inhibition of metabolism of the following active substances was found: tricyclic antidepressant (representing