Patienter med kreatininclearence mellem 30 og 60 ml/ min bør kun behandles med lavest dosiskombination af ramipril og hydrochlorothiazid efter administration af ramipril alene.
Patients with creatinine clearance levels between 30 and 60 ml/ min should only be treated with the lowest fixed dose combination of ramipril and hydrochlorothiazide after administration of ramipril alone.