I et åbent forsøg afsluttet i 1998 med HIV- smittede, klinisk stabile børn ses en signifikant forskel (p = 0, 03) i de påviselige RNA- niveauer efter en 48 ugers triple- behandling (ritonavir + zidovudine + lamivudine).
In an open label trial completed in 1998 in HIV infected, clinically stable children there was a significant difference (p = 0.03) in the detectable RNA levels in favour of a triple regimen (ritonavir, zidovudine and lamivudine) following 48 weeks treatment.