En metaanalyse af placebokontrollerede kliniske forsøg af antidepressive lægemidler til behandling af psykiske lidelser viste en forøget risiko for selvmordsadfærd med anti - depressiva sammenlignet med placebo hos patienter under 25 år.
A meta-analysis of placebo- controlled clinical trials of antidepressants medicinal products in psychiatric disorders showed an increased risk of suicidal behaviour with antidepressants compared to placebo in patients less than 25 years old Cases of suicidal thoughts and suicidal behaviours have been reported during duloxetine therapy or early after treatment discontinuation (see section 4.8).