Et klinisk interaktionsforsøg udført in vivo viste, at administration af aluminium og magnesiumhydroxid enten to timer før eller sammen med strontiumranelat gav en mindre nedsættelse i strontiumranelats absorption (AUC faldt med 20- 25%), mens absorptionen var næsten upåvirket, når antacida blev givet to timer efter strontiumranelat.
An in vivo clinical interaction study showed that the administration of aluminium and magnesium hydroxides either two hours before or together with strontium ranelate caused a slight decrease in the absorption of strontium ranelate (20-25% AUC decrease), while absorption was almost unaffected when the antacid was given two hours after strontium ranelate.