53 Biotransformation Sunitinib metaboliseres hovedsageligt af CYP3A4, det cytochrom P450- enzym som producerer dets aktive hovedmetabolit, og som derefter metaboliseres yderligere af CYP3A4.
Biotransformation Sunitinib is metabolized primarily by CYP3A4, the cytochrome P450 enzyme, which produces its primary active metabolite, which is then further metabolized by CYP3A4.