For personer med nedsat immunforsvar (uanset om det skyldes immunsuppresiv behandling, en genetisk fejl, HIV- infektion eller andre årsager) vil et beskyttende immunrespons for Hib and MenC konjugater muligvis ikke blive opnået.
In individuals with impaired immune responsiveness (whether due to the use of immunosuppressive therapy, a genetic defect, human immunodeficiency virus (HIV) infection, or other causes) a protective immune response to Hib and MenC conjugate vaccines may not be obtained.