Nedsat nyrefunktion: stavudin clearance falder på samme måde som kreatinin clearance falder; Det anbefales derfor, at Zerit dosen justeres hos patienter med nedsat nyrefunktion (se 4. 2 Dosering og indgivelsesmåde).
Renal impairment: the clearance of stavudine decreases as creatinine clearance decreases; therefore, it is recommended that the dosage of Zerit be adjusted in patients with reduced renal function (see section 4.2).