14- fold stigning i den systemiske eksponering for darunavir ved administration af en peroral enkeltdosis darunavir på 600 mg i kombination med ritonavir 100 mg x 2 (se pkt.
The overall pharmacokinetic enhancement effect by ritonavir was an approximate 14-fold increase in the systemic exposure of darunavir when a single dose of 600 mg darunavir was given orally in combination with ritonavir at 100 mg b.i.d.