Endvidere er det usandsynligt, at clofarabin skulle hæmme et af de 5 største humane CYP- isoformer (1A2, 2C9, 2C19, 2D6 og 3A4) eller inducere 2 af disse isoformer (1A2 og 3A4) ved de plasma- koncentrationer, der opnås efter en intravenøs infusion af 52 mg/ m2/ dag.
In addition, clofarabine is unlikely to inhibit any of the major 5 human CYP isoforms (1A2, 2C9, 2C19, 2D6 and 3A4) or to induce 2 of these isoforms (1A2 and 3A4) at the plasma concentrations achieved following intravenous infusion of 52 mg/ m2/ day.