Den påviselige medianclearance af lamotrigin var 0, 31, 0, 24 og 0, 10 ml/ min. / kg hos patienter med nedsat leverfunktion i henholdsvis klasse A, B eller C (Child- Pugh- klassificering) i forhold til 0, 34 ml/ min. / kg hos den raske kontrolgruppe.
The median apparent clearance of lamotrigine was 0.31, 0.24 or 0.10 mL/ min/ kg in patients with Grade A, B, or C (Child-Pugh Classification) hepatic impairment, respectively, compared with 0.34 mL/ min/ kg in the healthy controls.