Derfor er en dosisjustering ikke nødvendig hos patienter med nedsat nyre - eller leverfunktion, selvom sikkerheden og virkningen af hydroxocobalamin ikke er blevet undersøgt hos disse patienter.
Renal and hepatic impairments Although the safety and efficacy of hydroxocobalamin have not been studied in renal and hepatic impairments, Cyanokit is administered as emergency therapy in an acute, life-threatening situation only and no dosage adjustment is required in these patients.