Clomipramin og dets vigtigste metabolit, desmethylclomipramin, forhindrer en række neurotransmittere i at blive genoptaget i nerveceller i hjernen og rygmarven.
In the body, clomipramine and its major metabolite, desmethylclomipramine prevent some neurotransmitters from being taken back up into nerve cells in the brain and spinal cord.