Både clomipramin og desmethylclomipramin bidrager til effekten af Clomicalm: clomipramin er en potent og selektiv 5- HT reuptake- hæmmer, medens desmethylclopramin er en potent og selektiv noradrenalin reuptake- hæmmer.
Both clomipramine and desmethylclomipramine contribute to the effects of Clomicalm: clomipramine is a potent and selective 5-HT reuptake inhibitor while desmethylclomipramine is a potent and selective noradrenaline reuptake inhibitor.