Metabolisme Eksperimentelle data tyder på, at cytokrom P450- systemet er involveret i melatoninmetabolismen via isoenzymerne CYP1A1, CYP1A2 og muligvis CYP2C19.
Biotransformation Experimental data suggest that isoenzymes CYP1A1, CYP1A2 and possibly CYP2C19 of the cytochrome P450 system are involved in melatonin metabolism.