I et stort, placebo- kontrolleret, klinisk forsøg opvejede de modsatte virkninger af aliskiren (150 mg eller 300 mg) og hydrochlorthiazid (12, 5 mg eller 25 mg) mht. serumkalium omtrent hinanden hos mange patienter.
In a large placebo-controlled clinical trial, the opposite effects of aliskiren (150 mg or 300 mg) and hydrochlorothiazide (12.5 mg or 25 mg) on serum potassium approximately balanced each other in many patients.