Steady state plasma farmokokinetiske (PK) parametre for amprenavir blev ikke signifikant påvirket ved samtidig administration af dette orale præventionsmiddel, men ritonavir AUC( 0- τ) og Cmax var henholdsvis 45% og 63% højere sammenlignet med baggrundsdata for kvinder doseret med fosamprenavir/ ritonavir alene.
Steady state plasma amprenavir pharmacokinetic (PK) parameters were not significantly affected by co-administration with this oral contraceptive; however, ritonavir AUC(0- τ) and Cmax were 45% and 63% higher, respectively, compared to historical data in female subjects dosed with fosamprenavir / ritonavir alone.