Rifabutin (300 mg 1 gang dagligt) nedsatte Cmax (maksimal plasmakoncentration) og AUC (arealet under plasmakoncentrationstidskurven) af posaconazol til henholdsvis 57% og 51%.
4 Rifabutin (300 mg once a day) decreased the Cmax (maximum plasma concentration) and AUC (area under the plasma concentration time curve) of posaconazole to 57% and 51%, respectively.