Arava må ikke anvendes til patienter med: • leversygdom • svær immundefekt, f. eks. erhvervet immundefektsyndrom (AIDS) • ringe knoglemarvsfunktion eller lavt antal blodlegemer (røde blodlegemer, hvide blodlegemer eller trombocytter) forårsaget af andre lidelser end rheumatoid arthritis eller arthritis psoriatica • alvorlige infektioner • moderat til alvorlig nyrelidelse • alvorlig hypoproteinæmi (lave blodproteinniveauer).
Arava should not be used in patients with: • liver disease, • severe immunodeficiency states, such as acquired immune deficiency syndrome (AIDS), • poor bone marrow function or low blood cell counts (red cells, white cells or platelets) caused by conditions other than rheumatoid or psoriatic arthritis, • serious infections, • moderate to severe kidney disease, • severe hypoproteinaemia (low blood protein levels).