Gentagen administration af Clomicalm forårsager moderate stigninger i plasmakoncentrationer, akkumuleringsratio efter oral administration to gange daglig var 1. 2 for clomipramin og 1. 6 for desmethylclomipramin, steady state blev nået indenfor 3 dage.
Repeated administration of Clomicalm causes moderate increases in plasma concentrations, accumulation ratios after oral administration twice daily were 1.2 for clomipramine and 1.6 for desmethylclomipramine, with steady state being reached within 3 days.