Muligheden for hypotensive virkninger kan reduceres ved at seponere den diuretiske behandling og dermed øge volumen - eller saltindtaget før initiering af behandlingen med lave og gradvist større doser af perindopril.
After an assessment of the documentation provided by the MAH and an evaluation of the current EU- wide clinical practices relating to the use of COVERSYL, the following was considered to be the most suitable harmonised Section 4.1 indications text: