For at undgå protrombotisk effekt i begyndelsen af coumarinbehandlingen, bør parenteral antikoagulationsbehandling forsættes i 4- 5 dage (se indlægsseddel for oralt antikoagulerende middel).
To avoid prothrombotic effects when initiating coumarin, continue parenteral anticoagulation for 4 to 5 days (see oral anticoagulant package insert for information).