Antigenet er produceret ved kultur af genteknologisk fremstillede gærceller (Saccharomyces cerevisiae), som bærer genet, der koder for det vigtigste overfladeantigen hos hepatitis B virus (HBV).
The antigen is produced by culture of genetically-engineered yeast cells (Saccharomyces cerevisiae) which carry the gene which codes for the major surface antigen of the hepatitis B virus (HBV).