Samtidig administration af multiple doser af sitagliptin (50 mg to gange dagligt) og metformin (1. 000 mg to gange dagligt) ændrede ikke hverken sitagliptins eller metformins farmakokinetik betydeligt hos patienter med type 2- diabetes.
Co-administration of multiple doses of sitagliptin (50 mg twice daily) and metformin (1,000 mg twice daily) did not meaningfully alter the pharmacokinetics of either sitagliptin or metformin in patients with type 2 diabetes.