Hos patienter med stor metabolisme var AUC24 og Cmax for darifenacin 95% og 128% højere ved doseringen 30 mg 1 gang daglig, når erythromycin (moderat CYP3A4 hæmmer) blev co- administreret med darifenacin, end når darifenacin blev taget alene.
Darifenacin AUC24 and Cmax from 30 mg once daily dosing in subjects who are extensive metabolisers were 95% and 128% higher when erythromycin (moderate CYP3A4 inhibitor) was co-administered with darifenacin than when darifenacin was taken alone.