Clopidogrel hæmmer selektivt at adenosindiphosphat (ADP) bindes til dets trombocytreceptor, og som følge deraf, at ADP aktiverer GBIIb- IIIa- komplekset, og derved hæmmer clopidogrel trombocytaggregationen.
Clopidogrel selectively inhibits the binding of adenosine diphosphate (ADP) to its platelet receptor, and the subsequent ADP-mediated activation of the GPIIb/IIIa complex, thereby inhibiting platelet aggregation.