Ældre patienter Farmakokinetiske data fra fastende ældre patienter med ET (i alderen 65- 75 år) sammenlignet med fastende voksne patienter (i alderen 22- 50 år) viser, at Cmax og AUC for anagrelid var henholdsvis 36% og 61% højere hos ældre patienter, hvorimod Cmax og AUC for den aktive metabolit 2- amino - 5, 6- dichlor- 3, 4- dihydroquinazolin var henholdsvis 42% og 37% lavere hos ældre patienter.
Elderly Pharmacokinetic data from fasting elderly patients with ET (age range 65-75 years) compared to fasting adult patients (age range 22-50 years) indicate that the Cmax and AUC of anagrelide were 36% and 61% higher respectively in elderly patients, but that the Cmax and AUC of the active metabolite, 2- amino-5, 6-dichloro-3, 4-dihydroquinazoline, were 42% and 37% lower respectively in the elderly patients.