Confocal microscopic pictures of laminin expression of EpH4 cells 7 days after incubation of EpH4 cells with MM, GM, and matrigel-coated GM or without microspheres. EpH4 cells were cultured by the conventional 3D and 2D monolayer methods. The number of EpH4 cells added initially was 1 × 10 4 /well while that of microspheres was 1 × 10 2 or 1 × 10 3 /well. Scale bar. 100 μm.