Binding of biotinylated Aβ42 to Amytrapper in (A) human serum spiked with bio-Aβ42 and (B) human plasma spiked with bio-Aβ42. Sepharose (–) act as a negative control. Values are expressed in absorbance units presented as Mean±SEM from triplicate measurements. A) Student's t-test was used to determine significance. *p < 0.05, **p < 0.01, ***p < 0.001. B) Student's t-test was used to determine significance. *p < 0.05, **p < 0.01, ***p < 0.001.