Suppression of mTOR signaling abrogates DDX5-induced cell proliferation. ( A,B ) Western blot analysis of DDX5, p-mTOR(S2448), mTOR, p-S6K1(T389) and S6K1 in DDX5 or Vector transfected KATO III and NCI-N87 cells incubated with the indicated concentration of everolimus (EVE) or DMSO for 48 hr. β-actin was used as loading control. ( C,D ) CCK-8 analysis of gastric cancer cell proliferation in the presence or absence of everolimus for 48 hr (*p