fuckyeahmolecularbiology:  Of the 100 billion neurons in your brain, Purkinje neurons are some of the largest. Among other things, these cells are the masters of motor coordination in the cerebellar cortex. Toxic exposure such as alcohol and lithium, autoimmune diseases, genetic mutations including autism and neurodegenerative diseases can negatively affect human Purkinje cells. Image Source: The Wellcome Trust.