MI-specific miRNA and TF mediated regulatory network and its structure and functional features.(A). The MI-specific miRNA and TF mediated regulatory network was composed of MIgenes (circles), MImiRNAs (triangles) and TFs (diamonds). This network consists of 438 nodes and 1,780 links. (B). Degree distribution of all the nodes in the network, and degree distribution of genes, miRNAs and TFs in the network. (C). Significantly-enriched KEGG pathways for MIgenes in the network (cancer pathways removed). p-value was adjusted using the Benjamini-Hochberg multiple testing correction and a p-value of <0.05 was used as a threshold to select significant KEGG pathways. '*' indicated the pathways belonged to cardiovascular disease pathways in KEGG.