Not all clots are the same Thrombi in patients with AF are predominately fibrin-rich Thrombi in coronary artery disease (CAD) tend to be platelet-rich Anticoagulants reduce the conversion of fibrinogen to fibrin Aspirin, and other antiplatelets, inhibit aggregation of thrombi caused by CAD but do not impact upon fibrin production ridge.icu.ac.jp Lip GYH.