Three types of gene therapy: Monogenic gene therapy Provides genes to encode for the production of a specific protein Cystic fibrosis, Muscular dystrophy, Sickle cell disease, Haemophilia, SCID Suicide gene therapy Provide 'suicide' genes to target cancer cells for destruction Cancer Antisense gene therapy Provides a single stranded gene in an'antisense' (backward) orientation to block the production of harmful proteins AIDS/HIV