Representative V TE recordings. The recordings obtained with the final protocol are shown for WT (A) and cftr -/- B6;129 mice (B). Three phases was observed: baseline V TE after Cl - solution perfusion, V TEAmil. after the addition of amiloride (Amil.) and V TELowCl - after the replacement of Cl - solution with a solution of low Cl - concentration (LowCl - ). The inhibitory effect on Cl - secretion of inhibitor-172 and inhibitor-172 plus DIDS was demonstrated in WT mice.