Cytochalasin D treatment of HGFs abolished the T. denticola OM-induced enhancement of bead uptake. HGFs were counted and exposed to CIM control (Cont) or T. denticola OM (0.192 ng of OM/HGF for 1 h). Cells were washed free of the extract, recounted, and then incubated in either α-MEM or 1 μM cytochalasin D (Cyt D) for 1 h. PI is expressed as mean ± SE (three independent samples of 10,000 cells each). ∗, P