Effect of V. atypica OM challenge on HGF phagocytosis phenotype. (A) HGFs were exposed to CIM (negative control), T. denticola OM (positive control), or V. atypica OM (0.192 ng [dry weight] of OM/HGF cell for 1 h). In contrast to T. denticola , V. atypica OM pretreatment induced a decrease in collagen (Col)-coated bead phagocytosis and no statistically significant change in BSA-coated bead uptake. For each condition, three independent samples of 10,000 cells each were assayed (mean ± SE). Data shown are expressed as percent difference from negative control HGFs. ∗, P = 0.001; ∗∗, P