Representative photography of 5-MeC and DNMT1 immunohistochemistry. The 5-MeC photography in A – E ; The DNMT1 photos in F – J . ( A , F ) High-grade urothelial carcinoma showing high levels of both 5-MeC and DNMT1; ( B , G ) Low-grade urothelial carcinoma showing high levels of both 5-MeC and DNMT1; ( C , H ) High-grade urothelial carcinoma with glandular differentiation, showing high 5-MeC but low DNMT1 levels. ( D , I ) High-grade urothelial carcinoma with squamous differentiation, showing low levels of both 5-MeC and DNMT1; ( E , J ) High-grade urothelial carcinoma showing low levels of both 5-MeC and DNMT1. Bar = 200 µm.