Mice altered genetically to make more protein S (hPS-TG) mice showed less apoptosis of islet ?-cells. As the insulin (green) stained area decreased, the area of glucagon (red) staining was significantly increased in the WT/ Streptozotocin (induces beta cell death) group compared with the WT/Saline Control group but remained unchanged in the hPS TG/ Streptozotocin compared with the saline-treated group / Credit: Diabetes