Genomic Imprinting Normal Igf2 allele is expressed Paternal chromosome Maternal chromosome Normal Igf2 allele is not expressed Mutant Igf2 allele inherited from mother (a) Homozygote Wild-type mouse (normal size) Mutant Igf2 allele inherited from father Normal size mouse (wild type) Dwarf mouse (mutant) Normal Igf2 allele is expressed Mutant Igf2 allele is expressed Mutant Igf2 allele is not expressed Normal Igf2 allele is not expressed (b) Heterozygotes